-
2
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
DOI 10.1056/NEJMoa032158
-
Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004;350:2645-2653. (Pubitemid 38787999)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.26
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
Woods, R.4
Elliott, W.M.5
Buzatu, L.6
Cherniack, R.M.7
Rogers, R.M.8
Sciurba, F.C.9
Coxson, H.O.10
Pare, P.D.11
-
3
-
-
0141928029
-
Chronic obstructive pulmonary disease: Molecular and cellular mechanisms
-
Barnes PJ, Shapiro SD, Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J 2003;22:672-688. (Pubitemid 37258549)
-
(2003)
European Respiratory Journal
, vol.22
, Issue.4
, pp. 672-688
-
-
Barnes, P.J.1
Shapiro, S.D.2
Pauwels, R.A.3
-
4
-
-
33646554531
-
Inflammatory cells in the airways in COPD
-
DOI 10.1136/thx.2004.024463
-
O'Donnell R, Breen D, Wilson S, Djukanovic R. Inflammatory cells in the airways in COPD. Thorax 2006;61:448-454. (Pubitemid 43723331)
-
(2006)
Thorax
, vol.61
, Issue.5
, pp. 448-454
-
-
O'Donnell, R.1
Breen, D.2
Wilson, S.3
Djukanovic, R.4
-
5
-
-
4344675455
-
Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
-
DOI 10.1016/S0140-6736(04)16900-6, PII S0140673604169006
-
Hogg JC. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 2004;364:709-721. (Pubitemid 39140629)
-
(2004)
Lancet
, vol.364
, Issue.9435
, pp. 709-721
-
-
Hogg, J.C.1
-
6
-
-
33749261659
-
Adenosine 59-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
-
DOI 10.1016/j.pharmthera.2005.04.013, PII S0163725806000660
-
Bours MJ, Swennen EL, Di Virgilio F, Cronstein BN, Dagnelie PC. Adenosine 59-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther 2006;112:358-404. (Pubitemid 44486409)
-
(2006)
Pharmacology and Therapeutics
, vol.112
, Issue.2
, pp. 358-404
-
-
Bours, M.J.L.1
Swennen, E.L.R.2
Di, V.F.3
Cronstein, B.N.4
Dagnelie, P.C.5
-
7
-
-
33644607461
-
Pathophysiology and therapeutic potential of purinergic signaling
-
Burnstock G. Pathophysiology and therapeutic potential of purinergic signaling. Pharmacol Rev 2006;58:58-86.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 58-86
-
-
Burnstock, G.1
-
8
-
-
0141457730
-
Mechanisms of release of nucleotides and integration of their action as P2X- And P2Y-receptor activating molecules
-
DOI 10.1124/mol.64.4.785
-
Lazarowski ER, Boucher RC, Harden TK. Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y-receptor activating molecules. Mol Pharmacol 2003;64:785-795. (Pubitemid 37153046)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.4
, pp. 785-795
-
-
Lazarowski, E.R.1
Boucher, R.C.2
Harden, T.K.3
-
9
-
-
0031016802
-
Loss of ATP diphosphohydrolase activity with endothelial cell activation
-
DOI 10.1084/jem.185.1.153
-
Robson SC, Kaczmarek E, Siegel JB, Candinas D, Koziak K, Millan M, Hancock WW, Bach FH. Loss of ATP diphosphohydrolase activity with endothelial cell activation. J Exp Med 1997;185:153-163. (Pubitemid 27039449)
-
(1997)
Journal of Experimental Medicine
, vol.185
, Issue.1
, pp. 153-163
-
-
Robson, S.C.1
Kaczmarek, E.2
Siegel, J.B.3
Candinas, D.4
Koziak, K.5
Millan, M.6
Hancock, W.W.7
Bach, F.H.8
-
10
-
-
33646826840
-
Adenosine signaling in asthma and chronic obstructive pulmonary disease
-
DOI 10.1097/01.mcp.0000199002.46038.cb, PII 0006319820060100000011
-
Mohsenin A, Blackburn MR. Adenosine signaling in asthma and chronic obstructive pulmonary disease. Curr Opin Pulm Med 2006;12:54-59. (Pubitemid 44378579)
-
(2006)
Current Opinion in Pulmonary Medicine
, vol.12
, Issue.1
, pp. 54-59
-
-
Mohsenin, A.1
Blackburn, M.R.2
-
11
-
-
55849114101
-
A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
-
Eckle T, Grenz A, Laucher S, Eltzschig HK. A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice. J Clin Invest 2008;118:3301-3315.
-
(2008)
J Clin Invest
, vol.118
, pp. 3301-3315
-
-
Eckle, T.1
Grenz, A.2
Laucher, S.3
Eltzschig, H.K.4
-
12
-
-
69749111918
-
ATP in the pathogenesis of lung emphysema
-
Mortaz E, Braber S, Nazary M, Givi ME, Nijkamp FP, Folkerts G. ATP in the pathogenesis of lung emphysema. Eur J Pharmacol 2009;619:92-96.
-
(2009)
Eur J Pharmacol
, vol.619
, pp. 92-96
-
-
Mortaz, E.1
Braber, S.2
Nazary, M.3
Givi, M.E.4
Nijkamp, F.P.5
Folkerts, G.6
-
13
-
-
77952305210
-
Extracellular adenosine triphosphate and chronic obstructive pulmonary disease
-
Lommatzsch M, Cicko S, Müller T, Lucattelli M, Bratke K, Stoll P, Grimm M, Dürk T, Zissel G, Ferrari D, et al. Extracellular adenosine triphosphate and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2010;181:928-934.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 928-934
-
-
Lommatzsch, M.1
Cicko, S.2
Müller, T.3
Lucattelli, M.4
Bratke, K.5
Stoll, P.6
Grimm, M.7
Dürk, T.8
Zissel, G.9
Ferrari, D.10
-
14
-
-
3042781027
-
A putative osmoreceptor system that controls neutrophil function through the release of ATP, its conversion to adenosine, and activation of A2 adenosine and P2 receptors
-
DOI 10.1189/jlb.0204066
-
Chen Y, Shukla A, Namiki S, Insel PA, Junger WG. A putative osmoreceptor system that controls neutrophil function through the release of ATP, its conversion to adenosine, and activation of A2 adenosine and P2 receptors. J Leukoc Biol 2004;76:245-253. (Pubitemid 38857193)
-
(2004)
Journal of Leukocyte Biology
, vol.76
, Issue.1
, pp. 245-253
-
-
Chen, Y.1
Shukla, A.2
Namiki, S.3
Insel, P.A.4
Junger, W.G.5
-
15
-
-
0742323132
-
2 receptor
-
Meshki J, Tuluc F, Bredetean O, Ding Z, Kunapuli SP. Molecular mechanism of nucleotide-induced primary granule release in human neutrophils: role for the P2Y2 receptor. Am J Physiol 2004;286:C264-C271. (Pubitemid 38146350)
-
(2004)
American Journal of Physiology - Cell Physiology
, vol.286
, Issue.2
-
-
Meshki, J.1
Tuluc, F.2
Bredetean, O.3
Ding, Z.4
Kunapuli, S.P.5
-
16
-
-
0029666263
-
P(2U) agonists induce chemotaxis and actin polymerization in human neutrophils and differentiated HL60 cells
-
DOI 10.1074/jbc.271.26.15597
-
Verghese MW, Kneisler TB, Boucheron JA. P2U agonists induce chemotaxis and actin polymerization in human neutrophils and differentiated HL60 cells. J Biol Chem 1996;271:15597-15601. (Pubitemid 26225333)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.26
, pp. 15597-15601
-
-
Verghese, M.W.1
Kneisler, T.B.2
Boucheron, J.A.3
-
17
-
-
33845708770
-
ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors
-
DOI 10.1126/science.1132559
-
Chen Y, Corriden R, Inoue Y, Yip L, Hashiguchi N, Zinkernagel A, Nizet V, Insel PA, Junger WG. ATPrelease guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science 2006;314:1792-1795. (Pubitemid 44969094)
-
(2006)
Science
, vol.314
, Issue.5806
, pp. 1792-1795
-
-
Chen, Y.1
Corriden, R.2
Inoue, Y.3
Yip, L.4
Hashiguchi, N.5
Zinkernagel, A.6
Nizet, V.7
Insel, P.A.8
Junger, W.G.9
-
18
-
-
52149098412
-
A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis
-
Inoue Y, Chen Y, Hirsh MI, Yip L, Junger WG. A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis. Shock 2008;30:173-177.
-
(2008)
Shock
, vol.30
, pp. 173-177
-
-
Inoue, Y.1
Chen, Y.2
Hirsh, M.I.3
Yip, L.4
Junger, W.G.5
-
19
-
-
0035253835
-
Nucleotide receptors: An emerging family of regulatory molecules in blood cells
-
DOI 10.1182/blood.V97.3.587
-
Di Virgilio F, Chiozzi P, Ferrari D, Falzoni S, Sanz JM, Morelli A, Torboli M, Bolognesi G, Baricordi OR. Nucleotide receptors: an emerging family of regulatory molecules in blood cells. Blood 2001;97:587-600. (Pubitemid 32113390)
-
(2001)
Blood
, vol.97
, Issue.3
, pp. 587-600
-
-
Di, V.F.1
Chiozzi, P.2
Ferrari, D.3
Falzoni, S.4
Sanz, J.M.5
Morelli, A.6
Torboli, M.7
Bolognesi, G.8
Baricordi, O.R.9
-
20
-
-
49649084960
-
2+ increases and cytokine secretion
-
2+ increases and cytokine secretion. J Immunol 2008;181:2181-2188.
-
(2008)
J Immunol
, vol.181
, pp. 2181-2188
-
-
Myrtek, D.1
Müller, T.2
Geyer, V.3
Derr, N.4
Ferrari, D.5
Zissel, G.6
Dürk, T.7
Sorichter, S.8
Luttmann, W.9
Kuepper, M.10
-
21
-
-
33745088086
-
7 receptor
-
DOI 10.1182/blood-2005-07-2994
-
Gu BJ, Wiley JS. Rapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X7 receptor. Blood 2006;107:4946-4953. (Pubitemid 43882649)
-
(2006)
Blood
, vol.107
, Issue.12
, pp. 4946-4953
-
-
Gu, B.J.1
Wiley, J.S.2
-
22
-
-
0027689975
-
Stimulation of the rat alveolar macrophage respiratory burst by extracellular adenine nucleotides
-
Murphy JK, Livingston FR, Gozal E, Torres M, Forman HJ. Stimulation of the rat alveolar macrophage respiratory burst by extracellular adenine nucleotides. Am J Respir Cell Mol Biol 1993;9:505-510. (Pubitemid 2007510)
-
(1993)
AM.J.RESPIR.CELL MOL.BIOL.
, vol.9
, Issue.5
, pp. 505-510
-
-
Murphy, J.K.1
Livingston, F.R.2
Gozal, E.3
Torres, M.4
Forman, H.J.5
-
23
-
-
20144375454
-
7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain
-
DOI 10.1016/j.pain.2005.01.002
-
Chessell IP, Hatcher JP, Bountra C, Michel AD, Hughes JP, Green P, Egerton J, Murfin M, Richardson J, Peck WL, et al. Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain. Pain 2005;114:386-396. (Pubitemid 40385877)
-
(2005)
Pain
, vol.114
, Issue.3
, pp. 386-396
-
-
Chessell, I.P.1
Hatcher, J.P.2
Bountra, C.3
Michel, A.D.4
Hughes, J.P.5
Green, P.6
Egerton, J.7
Murfin, M.8
Richardson, J.9
Peck, W.L.10
Grahames, C.B.A.11
Casula, M.A.12
Yiangou, Y.13
Birch, R.14
Anand, P.15
Buell, G.N.16
-
24
-
-
0034885782
-
Human SLPI inactivation after cigarette smoke exposure in a new in vivo model of pulmonary oxidative stress
-
Cavarra E, Lucattelli M, Gambelli F, Bartalesi B, Fineschi S, Szarka A, Giannerini F, Martorana PA, Lungarella G. Human SLPI inactivation after cigarette smoke exposure in a new in vivo model of pulmonary oxidative stress. Am J Physiol 2001;281:L412-L417.
-
(2001)
Am J Physiol
, vol.281
-
-
Cavarra, E.1
Lucattelli, M.2
Gambelli, F.3
Bartalesi, B.4
Fineschi, S.5
Szarka, A.6
Giannerini, F.7
Martorana, P.A.8
Lungarella, G.9
-
25
-
-
34547655975
-
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells
-
DOI 10.1038/nm1617, PII NM1617
-
Idzko M, Hammad H, van Nimwegen M, Kool M, Willart MA, Muskens F, Hoogsteden HC, Luttmann W, Ferrari D, Di Virgilio F, et al. Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nat Med 2007;13:913-919. (Pubitemid 47222044)
-
(2007)
Nature Medicine
, vol.13
, Issue.8
, pp. 913-919
-
-
Idzko, M.1
Hammad, H.2
Van, N.M.3
Kool, M.4
Willart, M.A.M.5
Muskens, F.6
Hoogsteden, H.C.7
Luttmann, W.8
Ferrari, D.9
Di Jr., V.F.10
Virchow, J.C.11
Lambrecht, B.N.12
-
27
-
-
25444476938
-
Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke
-
DOI 10.1164/rccm.200411-1549OC
-
Martorana PA, Beume R, Lucattelli M, Wollin L, Lungarella G. Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke. Am J Respir Crit Care Med 2005;172:848-853. (Pubitemid 41369068)
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.172
, Issue.7
, pp. 848-853
-
-
Martorana, P.A.1
Beume, R.2
Lucattelli, M.3
Wollin, L.4
Lungarella, G.5
-
28
-
-
66449110381
-
Self-regulation of inflammatory cell trafficking in mice by the leukocyte surface apyrase CD39
-
Hyman MC, Petrovic-Djergovic D, Visovatti SH, Liao H, Yanamadala S, Bouis D, et al. Self-regulation of inflammatory cell trafficking in mice by the leukocyte surface apyrase CD39. J Clin Invest 2009;119:1136-1149.
-
(2009)
J Clin Invest
, vol.119
, pp. 1136-1149
-
-
Hyman, M.C.1
Petrovic-Djergovic, D.2
Visovatti, S.H.3
Liao, H.4
Yanamadala, S.5
Bouis, D.6
-
29
-
-
4444322565
-
Tumor necrosis factor-a drives 70% of cigarette smoke-induced emphysema in the mouse
-
DOI 10.1164/rccm.200404-511OC
-
Churg A, Wang RD, Tai H, Wang X, Xie C, Wright JL. Tumor necrosis factor-a drives 70% of cigarette smoke-induced emphysema in the mouse. Am J Respir Crit Care Med 2004;170:492-498. (Pubitemid 39209129)
-
(2004)
American Journal of Respiratory and Critical Care Medicine
, vol.170
, Issue.5
, pp. 492-498
-
-
Churg, A.1
Wang, R.D.2
Tai, H.3
Wang, X.4
Xie, C.5
Wright, J.L.6
-
30
-
-
13644267621
-
Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect
-
DOI 10.1152/ajplung.00317.2004
-
Stevenson CS, Coote K, Webster R, Johnston H, Atherton HC, Nicholls A, Giddings J, Sugar R, Jackson A, Press NJ, et al. Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect. Am J Physiol 2005;288:L514-L522. (Pubitemid 40229517)
-
(2005)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.288
, Issue.3
-
-
Stevenson, C.S.1
Coote, K.2
Webster, R.3
Johnston, H.4
Atherton, H.C.5
Nicholls, A.6
Giddings, J.7
Sugar, R.8
Jackson, A.9
Press, N.J.10
Brown, Z.11
Butler, K.12
Danahay, H.13
-
31
-
-
47049114203
-
Denufosol: A review of studies with inhaled P2Y(2) agonists that led to phase 3
-
Kellerman D, Rossi Mospan A, Engels J, Schaberg A, Gorden J, Smiley L. Denufosol: a review of studies with inhaled P2Y(2) agonists that led to phase 3. Pulm Pharmacol Ther 2008;21:600-607.
-
(2008)
Pulm Pharmacol Ther
, vol.21
, pp. 600-607
-
-
Kellerman, D.1
Rossi Mospan, A.2
Engels, J.3
Schaberg, A.4
Gorden, J.5
Smiley, L.6
-
32
-
-
0035338445
-
7 nucleotide receptor mediation of membrane pore formation and superoxide generation in human promyelocytes and neutrophils
-
7 nucleotide receptor mediation of membrane pore formation and superoxide generation in human promyelocytes and neutrophils. J Immunol 2001;166:6754-6763.
-
(2001)
J Immunol
, vol.166
, pp. 6754-6763
-
-
Suh, B.C.1
Kim, J.S.2
Namgung, U.3
Ha, H.4
Kim, K.T.5
-
33
-
-
29644433257
-
The priming effect of extracellular UTP on human neutrophils: Role of calcium released from thapsigargin-sensitive intracellular stores
-
DOI 10.1007/s11302-005-0039-8
-
Tuluc F, Bredetean O, Brailoiu E, Meshki J, Garcia A, Dun NJ, Kunapuli SP. The priming effect of extracellular UTP on human neutrophils: role of calcium released from thapsigargin-sensitive intracellular stores. Purinergic Signal 2005;1:359-368. (Pubitemid 43019534)
-
(2005)
Purinergic Signalling
, vol.1
, Issue.4
, pp. 359-368
-
-
Tuluc, F.1
Bredetean, O.2
Brailoiu, E.3
Meshki, J.4
Garcia, A.5
Dun, N.J.6
Kunapuli, S.P.7
|