-
1
-
-
0025856717
-
TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
-
Ellisen, L.W. et al. TAN 1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66, 649-661 (1991). (Pubitemid 121001701)
-
(1991)
Cell
, vol.66
, Issue.4
, pp. 649-661
-
-
Ellisen, L.W.1
Bird, J.2
West, D.C.3
Soreng, A.L.4
Reynolds, T.C.5
Smith, S.D.6
Sklar, J.7
-
2
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
DOI 10.1126/science.1102160
-
Weng, A.P. et al. Activating mutations of NOTCH1 in human Tcell acute lymphoblastic leukemia. Science 306, 269-271 (2004). (Pubitemid 39336870)
-
(2004)
Science
, vol.306
, Issue.5694
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris IV, J.P.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
Blacklow, S.C.7
Look, A.T.8
Aster, J.C.9
-
3
-
-
33745045658
-
Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes
-
DOI 10.1128/MCB.01655-05
-
Malecki, M.J. et al. Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes. Mol. Cell. Biol. 26, 4642-4651 (2006). (Pubitemid 43877581)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.12
, pp. 4642-4651
-
-
Malecki, M.J.1
Sanchez-Irizarry, C.2
Mitchell, J.L.3
Histen, G.4
Xu, M.L.5
Aster, J.C.6
Blacklow, S.C.7
-
4
-
-
38549148417
-
Notch and cancer: A double-edged sword
-
DOI 10.1007/s00018-007-7164-1
-
Koch, U. & Radtke, F. Notch and cancer: a double-edged sword. Cell. Mol. Life Sci. 64, 2746-2762 (2007). (Pubitemid 351152259)
-
(2007)
Cellular and Molecular Life Sciences
, vol.64
, Issue.21
, pp. 2746-2762
-
-
Koch, U.1
Radtke, F.2
-
5
-
-
77953158971
-
Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma
-
Hanlon, L. et al. Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma. Cancer Res. 70, 4280-4286 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 4280-4286
-
-
Hanlon, L.1
-
6
-
-
65249125270
-
Inhibition of γsecretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma
-
e1746
-
Plentz, R. et al. Inhibition of γsecretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma. Gastroenterology 136, 1741-1749 e1746 (2009).
-
(2009)
Gastroenterology
, vol.136
, pp. 1741-1749
-
-
Plentz, R.1
-
7
-
-
4944241544
-
JAGGED1 expression is associated with prostate cancer metastasis and recurrence
-
DOI 10.1158/0008-5472.CAN-04-2500
-
Santagata, S. et al. JAGGED1 expression is associated with prostate cancer metastasis and recurrence. Cancer Res. 64, 6854-6857 (2004). (Pubitemid 39330990)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 6854-6857
-
-
Santagata, S.1
Demichelis, F.2
Riva, A.3
Varambally, S.4
Hofer, M.D.5
Kutok, J.L.6
Kim, R.7
Tang, J.8
Montie, J.E.9
Chinnaiyan, A.M.10
Rubin, M.A.11
Aster, J.C.12
-
8
-
-
10744223624
-
Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis
-
DOI 10.1016/S1535-6108(03)00140-5
-
Miyamoto, Y. et al. Notch mediates TGF αinduced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell 3, 565-576 (2003). (Pubitemid 36808651)
-
(2003)
Cancer Cell
, vol.3
, Issue.6
, pp. 565-576
-
-
Miyamoto, Y.1
Maitra, A.2
Ghosh, B.3
Zechner, U.4
Argani, P.5
Iacobuzio-Donahue, C.A.6
Sriuranpong, V.7
Iso, T.8
Meszoely, I.M.9
Wolfe, M.S.10
Hruban, R.H.11
Ball, D.W.12
Schmid, R.M.13
Leach, S.D.14
-
9
-
-
70849122697
-
Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations
-
Brennan, C. et al. Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS ONE 4, e7752 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Brennan, C.1
-
10
-
-
24944506696
-
High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
-
DOI 10.1158/0008-5472.CAN-05-1069
-
Reedijk, M. et al. High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res. 65, 8530-8537 (2005). (Pubitemid 41330622)
-
(2005)
Cancer Research
, vol.65
, Issue.18
, pp. 8530-8537
-
-
Reedijk, M.1
Odorcic, S.2
Chang, L.3
Zhang, H.4
Miller, N.5
McCready, D.R.6
Lockwood, G.7
Sean, E.8
-
11
-
-
41749118698
-
Notch signaling in leukemia
-
DOI 10.1146/annurev.pathmechdis.3.121806.154300
-
Aster, J.C., Pear, W.S. & Blacklow, S.C. Notch signaling in leukemia. Annu. Rev. Pathol. 3, 587-613 (2008). (Pubitemid 351488294)
-
(2008)
Annual Review of Pathology: Mechanisms of Disease
, vol.3
, pp. 587-613
-
-
Aster, J.C.1
Pear, W.S.2
Blacklow, S.C.3
-
12
-
-
55449135598
-
The molecular logic of Notch signaling-A structural and biochemical perspective
-
Gordon, W.R., Arnett, K.L. & Blacklow, S.C. The molecular logic of Notch signaling-a structural and biochemical perspective. J.Cell Sci. 121, 3109-3119 (2008).
-
(2008)
J. Cell Sci.
, vol.121
, pp. 3109-3119
-
-
Gordon, W.R.1
Arnett, K.L.2
Blacklow, S.C.3
-
13
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
DOI 10.1038/nrm2009, PII NRM2009
-
Bray, S.J. Notch signalling: a simple pathway becomes complex. Nature Rev. Mol. Cell Biol. 7, 678-689 (2006). (Pubitemid 44268213)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.9
, pp. 678-689
-
-
Bray, S.J.1
-
14
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
Kopan, R. & Ilagan, M.X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137, 216-233 (2009).
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
15
-
-
50849125368
-
More complicated than it looks: Assembly of Notch pathway transcription complexes
-
Kovall, R.A. More complicated than it looks: assembly of Notch pathway transcription complexes. Oncogene 27, 5099-5109 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 5099-5109
-
-
Kovall, R.A.1
-
16
-
-
65549121943
-
Notch signaling: The core pathway and its posttranslational regulation
-
Fortini, M.E. Notch signaling: the core pathway and its posttranslational regulation. Dev. Cell 16, 633-647 (2009).
-
(2009)
Dev. Cell
, vol.16
, pp. 633-647
-
-
Fortini, M.E.1
-
17
-
-
0141817915
-
The Notch Ligands, Jagged and Delta, Are Sequentially Processed by α-Secretase and Presenilin/γ-Secretase and Release Signaling Fragments
-
DOI 10.1074/jbc.M302659200
-
LaVoie, M.J. & Selkoe, D.J. The Notch ligands, Jagged and Delta, are sequentially processed by αsecretase and presenilin/γsecretase and release signaling fragments. J.Biol. Chem. 278, 34427-34437 (2003). (Pubitemid 37553289)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.36
, pp. 34427-34437
-
-
LaVoie, M.J.1
Selkoe, D.J.2
-
18
-
-
0038610845
-
The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and γ-secretase
-
DOI 10.1073/pnas.1230693100
-
Six, E. et al. The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and γsecretase. Proc. Natl Acad. Sci. USA 100, 7638-7643 (2003). (Pubitemid 36760022)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.13
, pp. 7638-7643
-
-
Six, E.1
Ndiaye, D.2
Laabi, Y.3
Brou, C.4
Gupta-Rossi, N.5
Israel, A.6
Logeat, F.7
-
19
-
-
0037648484
-
Notch-induced proteolysis and nuclear localization of the delta ligand
-
DOI 10.1074/jbc.C300016200
-
Bland, C.E., Kimberly, P. & Rand, M.D. Notch-induced proteolysis and nuclear localization of the Delta ligand. J.Biol. Chem. 278, 13607-13610 (2003). (Pubitemid 36799892)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.16
, pp. 13607-13610
-
-
Bland, C.E.1
Kimberly, P.2
Rand, M.D.3
-
20
-
-
0031846155
-
Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development
-
Klueg, K.M., Parody, T.R. & Muskavitch, M.A. Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development. Mol. Biol. Cell 9, 1709-1723 (1998). (Pubitemid 28337518)
-
(1998)
Molecular Biology of the Cell
, vol.9
, Issue.7
, pp. 1709-1723
-
-
Klueg, K.M.1
Parody, T.R.2
Muskavitch, M.A.T.3
-
21
-
-
77956298525
-
Canonical and non-canonical Notch ligands
-
D'Souza, B., Meloty-Kapella, L. & Weinmaster, G. Canonical and non-canonical Notch ligands. Curr. Top. Dev. Biol. 92, 73-129 (2010).
-
(2010)
Curr. Top. Dev. Biol.
, vol.92
, pp. 73-129
-
-
D'Souza, B.1
Meloty-Kapella, L.2
Weinmaster, G.3
-
22
-
-
0037424259
-
The C-terminal PDZ-ligand of JAGGED1 is essential for cellular transformation
-
DOI 10.1074/jbc.M211427200
-
Ascano, J.M., Beverly, L.J. & Capobianco, A.J. The Cterminal PDZ-ligand of JAGGED1 is essential for cellular transformation. J.Biol. Chem. 278, 8771-8779 (2003). (Pubitemid 36800634)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.10
, pp. 8771-8779
-
-
Ascano, J.M.1
Beverly, L.J.2
Capobianco, A.J.3
-
23
-
-
26844491357
-
The intracellular domain of Notch ligand Delta1 induces cell growth arrest
-
DOI 10.1016/j.febslet.2005.09.042, PII S0014579305011622
-
Kolev, V. et al. The intracellular domain of Notch ligand Delta1 induces cell growth arrest. FEBS Lett. 579, 5798-5802 (2005). (Pubitemid 41455666)
-
(2005)
FEBS Letters
, vol.579
, Issue.25
, pp. 5798-5802
-
-
Kolev, V.1
Kacer, D.2
Trifonova, R.3
Small, D.4
Duarte, M.5
Soldi, R.6
Graziani, I.7
Sideleva, O.8
Larman, B.9
Maciag, T.10
Prudovsky, I.11
-
24
-
-
0023226698
-
A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17
-
Gallahan, D., Kozak, C. & Callahan, R. A new common integration region (int?3) for mouse mammary tumor virus on mouse chromosome 17. J.Virol. 61, 218-220 (1987). (Pubitemid 17212466)
-
(1987)
Journal of Virology
, vol.61
, Issue.1
, pp. 218-220
-
-
Gallahan, D.1
Kozak, C.2
Callahan, R.3
-
25
-
-
0030920376
-
The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4)
-
Gallahan, D. & Callahan, R. The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4). Oncogene 14, 1883-1890 (1997). (Pubitemid 27217801)
-
(1997)
Oncogene
, vol.14
, Issue.16
, pp. 1883-1890
-
-
Gallahan, D.1
Callahan, R.2
-
26
-
-
0029871104
-
Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis
-
Gallahan, D. et al. Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis. Cancer Res. 56, 1775-1785 (1996). (Pubitemid 26118213)
-
(1996)
Cancer Research
, vol.56
, Issue.8
, pp. 1775-1785
-
-
Gallahan, D.1
Jhappan, C.2
Robinson, G.3
Hennighausen, L.4
Sharp, R.5
Kordon, E.6
Callahan, R.7
Merlino, G.8
Smith, G.H.9
-
27
-
-
0030820930
-
Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2
-
Capobianco, A.J., Zagouras, P., Blaumueller, C.M., Artavanis-Tsakonas, S. & Bishop, J.M. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Mol. Cell. Biol. 17, 6265-6273 (1997). (Pubitemid 27451170)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.11
, pp. 6265-6273
-
-
Capobianco, A.J.1
Zagouras, P.2
Blaumueller, C.M.3
Artavanis-Tsakonas, S.4
Bishop, J.M.5
-
28
-
-
50849085425
-
It's T-ALL about notch
-
Demarest, R.M., Ratti, F. & Capobianco, A.J. It's T-ALL about Notch. Oncogene 27, 5082-5091 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 5082-5091
-
-
Demarest, R.M.1
Ratti, F.2
Capobianco, A.J.3
-
29
-
-
0034902568
-
ic
-
DOI 10.1128/MCB.21.17.5925-5934.2001
-
Ronchini, C. & Capobianco, A.J. Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic). Mol. Cell. Biol. 21, 5925-5934 (2001). (Pubitemid 32737809)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.17
, pp. 5925-5934
-
-
Ronchini, C.1
Capobianco, A.J.2
-
30
-
-
77955657847
-
Notch1 induced mammary tumor development is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors
-
Ling, H., Sylvestre, J.R. & Jolicoeur, P. Notch1 induced mammary tumor development is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors. Oncogene 29, 4543-4554 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 4543-4554
-
-
Ling, H.1
Sylvestre, J.R.2
Jolicoeur, P.3
-
31
-
-
77955768470
-
Cyclin D1 is a direct target of JAG1 imediated Notch signaling in breast cancer
-
Cohen, B. et al. Cyclin D1 is a direct target of JAG1 imediated Notch signaling in breast cancer. Breast Cancer Res. Treat. 123, 113-124 (2010).
-
(2010)
Breast Cancer Res. Treat.
, vol.123
, pp. 113-124
-
-
Cohen, B.1
-
32
-
-
9144229104
-
Requirement for cyclin D3 in lymphocyte development and T cell leukemias
-
DOI 10.1016/S1535-6108(03)00301-5
-
Sicinska, E. et al. Requirement for cyclin D3 in lymphocyte development and Tcell leukemias. Cancer Cell 4, 451-461 (2003). (Pubitemid 38050042)
-
(2003)
Cancer Cell
, vol.4
, Issue.6
, pp. 451-461
-
-
Sicinska, E.1
Aifantis, I.2
Le Cam, L.3
Swat, W.4
Borowski, C.5
Yu, Q.6
Ferrando, A.A.7
Levin, S.D.8
Geng, Y.9
Von Boehmer, H.10
Sicinski, P.11
-
33
-
-
33750317437
-
Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc
-
DOI 10.1128/MCB.01091-06
-
Sharma, V.M. et al. Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c imyc. Mol. Cell. Biol. 26, 8022-8031 (2006). (Pubitemid 44631001)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.21
, pp. 8022-8031
-
-
Sharma, V.M.1
Calvo, J.A.2
Draheim, K.M.3
Cunningham, L.A.4
Hermance, N.5
Beverly, L.6
Krishnamoorthy, V.7
Bhasin, M.8
Capobianco, A.J.9
Kelliher, M.A.10
-
34
-
-
33746546368
-
C-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
-
DOI 10.1101/gad.1450406
-
Weng, A.P. et al. Cimyc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. Genes Dev. 20, 2096-2109 (2006). (Pubitemid 44157460)
-
(2006)
Genes and Development
, vol.20
, Issue.15
, pp. 2096-2109
-
-
Weng, A.P.1
Millholland, J.M.2
Yashiro-Ohtani, Y.3
Arcangeli, M.L.4
Lau, A.5
Wai, C.6
Del Bianco, C.7
Rodriguez, C.G.8
Sai, H.9
Tobias, J.10
Li, Y.11
Wolfe, M.S.12
Shachaf, C.13
Felsher, D.14
Blacklow, S.C.15
Pear, W.S.16
Aster, J.C.17
-
35
-
-
33745131039
-
Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice
-
DOI 10.1073/pnas.0603371103
-
Klinakis, A. et al. Myc is a Notch1 transcriptional target and a requisite for Notch1 induced mammary tumorigenesis in mice. Proc. Natl Acad. Sci. USA 103, 9262-9267 (2006). (Pubitemid 43902566)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.24
, pp. 9262-9267
-
-
Klinakis, A.1
Szaboks, M.2
Politi, K.3
Kiaris, H.4
Artavanis-Tsakonas, S.5
Efstratiadis, A.6
-
36
-
-
33845306813
-
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
-
DOI 10.1073/pnas.0606108103
-
Palomero, T. et al. NOTCH1 directly regulates c imYC and activates a feed?forward?loop transcriptional network promoting leukemic cell growth. Proc. Natl Acad. Sci. USA 103, 18261-18266 (2006). (Pubitemid 44871646)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.48
, pp. 18261-18266
-
-
Palomero, T.1
Wei, K.L.2
Odom, D.T.3
Sulis, M.L.4
Real, P.J.5
Margolin, A.6
Barnes, K.C.7
O'Neil, J.8
Neuberg, D.9
Weng, A.P.10
Aster, J.C.11
Sigaux, F.12
Soulier, J.13
Look, A.T.14
Young, R.A.15
Califano, A.16
Ferrando, A.A.17
-
37
-
-
71249134033
-
Notch Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1
-
Murata, J. et al. Notch Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1. J.Neurosci. Res. 87, 3521-3534 (2009).
-
(2009)
J. Neurosci. Res.
, vol.87
, pp. 3521-3534
-
-
Murata, J.1
-
38
-
-
69249156978
-
The notch target gene HES1 regulates cell cycle inhibitor expression in the developing pituitary
-
Monahan, P., Rybak, S. & Raetzman, L.T. The notch target gene HES1 regulates cell cycle inhibitor expression in the developing pituitary. Endocrinology 150, 4386-4394 (2009).
-
(2009)
Endocrinology
, vol.150
, pp. 4386-4394
-
-
Monahan, P.1
Rybak, S.2
Raetzman, L.T.3
-
39
-
-
48749089743
-
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2
-
Riccio, O. et al. Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. EMBO Rep. 9, 377-383 (2008).
-
(2008)
EMBO Rep.
, vol.9
, pp. 377-383
-
-
Riccio, O.1
-
40
-
-
34547484864
-
Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines
-
DOI 10.1016/j.yexcr.2007.04.027, PII S0014482707001814
-
Dohda, T. et al. Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines. Exp. Cell Res. 313, 3141-3152 (2007). (Pubitemid 47161022)
-
(2007)
Experimental Cell Research
, vol.313
, Issue.14
, pp. 3141-3152
-
-
Dohda, T.1
Maljukova, A.2
Liu, L.3
Heyman, M.4
Grander, D.5
Brodin, D.6
Sangfelt, O.7
Lendahl, U.8
-
41
-
-
74549133972
-
Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis
-
Mittal, S., Subramanyam, D., Dey, D., Kumar, R. & Rangarajan, A. Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis. Mol. Cancer 8, 128 (2009).
-
(2009)
Mol. Cancer
, vol.8
, pp. 128
-
-
Mittal, S.1
Subramanyam, D.2
Dey, D.3
Kumar, R.4
Rangarajan, A.5
-
42
-
-
77949261572
-
The oncogenic roles of Notch1 in astrocytic gliomas invitro and invivo
-
Xu, P. et al. The oncogenic roles of Notch1 in astrocytic gliomas invitro and invivo. J.Neurooncol. 97, 41-51 (2010).
-
(2010)
J. Neurooncol.
, vol.97
, pp. 41-51
-
-
Xu, P.1
-
43
-
-
77950455135
-
JAK-STAT is restrained by Notch to control cell proliferation of the Drosophila intestinal stem cells
-
Liu, W., Singh, S.R. & Hou, S.X. JAK-STAT is restrained by Notch to control cell proliferation of the Drosophila intestinal stem cells. J.Cell. Biochem. 109, 992-999 (2010).
-
(2010)
J. Cell. Biochem.
, vol.109
, pp. 992-999
-
-
Liu, W.1
Singh, S.R.2
Hou, S.X.3
-
44
-
-
36148993580
-
Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of γ-secretase
-
DOI 10.1074/jbc.M703649200
-
Li, T. et al. Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of γ-secretase. J.Biol. Chem. 282, 32264-32273 (2007). (Pubitemid 350106457)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.44
, pp. 32264-32273
-
-
Li, T.1
Wen, H.2
Brayton, C.3
Das, P.4
Smithson, L.A.5
Fauq, A.6
Fan, X.7
Crain, B.J.8
Price, D.L.9
Golde, T.E.10
Eberhart, C.G.11
Wong, P.C.12
-
45
-
-
33947166199
-
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKα kinases
-
DOI 10.1101/gad.1484707
-
Lefort, K. et al. Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKα kinases. Genes Dev. 21, 562-577 (2007). (Pubitemid 46409471)
-
(2007)
Genes and Development
, vol.21
, Issue.5
, pp. 562-577
-
-
Lefort, K.1
Mandinova, A.2
Ostano, P.3
Kolev, V.4
Calpini, V.5
Kolfschoten, I.6
Devgan, V.7
Lieb, J.8
Raffoul, W.9
Hohl, D.10
Neel, V.11
Garlick, J.12
Chiorino, G.13
Dotto, G.P.14
-
46
-
-
67650236862
-
Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2 imediated p53 degradation and up-regulating p53-dependent DR5 expression
-
Wang, C. et al. Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2 imediated p53 degradation and up-regulating p53-dependent DR5 expression. J.Biol. Chem. 284, 16183-16190 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 16183-16190
-
-
Wang, C.1
-
47
-
-
35948943021
-
Overexpressed active Notch1 induces cell growth arrest of HeLa cervical carcinoma cells
-
DOI 10.1111/j.1525-1438.2007.00927.x
-
Wang, L. et al. Overexpressed active Notch1 induces cell growth arrest of HeLa cervical carcinoma cells. Int. J.Gynecol. Cancer 17, 1283-1292 (2007). (Pubitemid 350077350)
-
(2007)
International Journal of Gynecological Cancer
, vol.17
, Issue.6
, pp. 1283-1292
-
-
Wang, L.1
Qin, H.2
Chen, B.3
Xin, X.4
Li, J.5
Han, H.6
-
48
-
-
16244418366
-
Constitutively active Notch1 induces growth arrest of HPV-positive cervical cancer cells via separate signaling pathways
-
DOI 10.1016/j.yexcr.2005.01.015
-
Talora, C. et al. Constitutively active Notch1 induces growth arrest of HPV-positive cervical cancer cells via separate signaling pathways. Exp. Cell Res. 305, 343-354 (2005). (Pubitemid 40462545)
-
(2005)
Experimental Cell Research
, vol.305
, Issue.2
, pp. 343-354
-
-
Talora, C.1
Cialfi, S.2
Segatto, O.3
Morrone, S.4
Kim Choi, J.5
Frati, L.6
Dotto, G.P.7
Gulino, A.8
Screpanti, I.9
-
49
-
-
67749093259
-
Crosstalk of Notch with p53 and p63 in cancer growth control
-
Dotto, G.P. Crosstalk of Notch with p53 and p63 in cancer growth control. Nature Rev. Cancer 9, 587-595 (2009).
-
(2009)
Nature Rev. Cancer
, vol.9
, pp. 587-595
-
-
Dotto, G.P.1
-
50
-
-
0035476048
-
Dynamics of Notch expression during murine prostate development and tumorigenesis
-
Shou, J., Ross, S., Koeppen, H., de Sauvage, F.J. & Gao, W.Q. Dynamics of notch expression during murine prostate development and tumorigenesis. Cancer Res. 61, 7291-7297 (2001). (Pubitemid 32951774)
-
(2001)
Cancer Research
, vol.61
, Issue.19
, pp. 7291-7297
-
-
Shou, J.1
Ross, S.2
Koeppen, H.3
De Sauvage, F.J.4
Gao, W.-Q.5
-
51
-
-
67749135444
-
Notch-1 signaling is lost in prostate adenocarcinoma and promotes PTEN gene expression
-
Whelan, J.T., Kellogg, A., Shewchuk, B.M., Hewan-Lowe, K. & Bertrand, F.E. Notch-1 signaling is lost in prostate adenocarcinoma and promotes PTEN gene expression. J.Cell. Biochem. 107, 992-1001 (2009).
-
(2009)
J. Cell. Biochem.
, vol.107
, pp. 992-1001
-
-
Whelan, J.T.1
Kellogg, A.2
Shewchuk, B.M.3
Hewan-Lowe, K.4
Bertrand, F.E.5
-
52
-
-
59449107891
-
Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase?9 and urokinase plasminogen activator
-
Bin Hafeez, B. et al. Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase?9 and urokinase plasminogen activator. Clin. Cancer Res. 15, 452-459 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 452-459
-
-
Bin Hafeez, B.1
-
53
-
-
33847403486
-
Notch signaling is necessary for epithelial growth arrest by TGF-β
-
DOI 10.1083/jcb.200612129
-
Niimi, H., Pardali, K., Vanlandewijck, M., Heldin, C.H. & Moustakas, A. Notch signaling is necessary for epithelial growth arrest by TGF-β. J.Cell Biol. 176, 695-707 (2007). (Pubitemid 46333983)
-
(2007)
Journal of Cell Biology
, vol.176
, Issue.5
, pp. 695-707
-
-
Niimi, H.1
Pardali, K.2
Vanlandewijck, M.3
Heldin, C.-H.4
Moustakas, A.5
-
54
-
-
24044513994
-
Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta; signaling
-
DOI 10.1038/sj.onc.1208528, PII 1208528
-
Sun, Y. et al. Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-β signaling. Oncogene 24, 5365-5374 (2005). (Pubitemid 43080106)
-
(2005)
Oncogene
, vol.24
, Issue.34
, pp. 5365-5374
-
-
Sun, Y.1
Lowther, W.2
Kato, K.3
Bianco, C.4
Kenney, N.5
Strizzi, L.6
Raafat, D.7
Hirota, M.8
Khan, N.I.9
Bargo, S.10
Jones, B.11
Salomon, D.12
Callahan, R.13
-
55
-
-
21244489623
-
Notch 1 oncoprotein antagonizes TGF-β/Smad-mediated cell growth suppression via sequestration of coactivator p300
-
DOI 10.1111/j.1349-7006.2005.00048.x
-
Masuda, S. et al. Notch1 oncoprotein antagonizes TGF-β/Smad-mediated cell growth suppression via sequestration of coactivator p300. Cancer Sci. 96, 274-282 (2005). (Pubitemid 40895075)
-
(2005)
Cancer Science
, vol.96
, Issue.5
, pp. 274-282
-
-
Masuda, S.1
Kumano, K.2
Shimizu, K.3
Imai, Y.4
Kurokawa, M.5
Ogawa, S.6
Miyagishi, M.7
Taira, K.8
Hirai, H.9
Chiba, S.10
-
56
-
-
67649304460
-
Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment
-
Demehri, S., Turkoz, A. & Kopan, R. Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment. Cancer Cell 16, 55-66 (2009).
-
(2009)
Cancer Cell
, vol.16
, pp. 55-66
-
-
Demehri, S.1
Turkoz, A.2
Kopan, R.3
-
57
-
-
77949534538
-
Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin
-
Dumortier, A. et al. Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin. PLoS ONE 5, e9258 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Dumortier, A.1
-
58
-
-
45149117788
-
Notch-deficient skin induces a lethal systemic B?lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity
-
Demehri, S. et al. Notch-deficient skin induces a lethal systemic B?lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity. PLoS Biol. 6, e123 (2008).
-
(2008)
PLoS Biol.
, vol.6
-
-
Demehri, S.1
-
59
-
-
43549123531
-
The role of the PTEN/AKT pathway in NOTCH1-induced leukemia
-
Palomero, T., Dominguez, M. & Ferrando, A.A. The role of the PTEN/AKT Pathway in NOTCH1 induced leukemia. Cell Cycle 7, 965-970 (2008). (Pubitemid 351679827)
-
(2008)
Cell Cycle
, vol.7
, Issue.8
, pp. 965-970
-
-
Palomero, T.1
Dominguez, M.2
Ferrando, A.A.3
-
60
-
-
0037941645
-
Activated Notch1 inhibits p53-induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway
-
DOI 10.1128/JVI.77.12.7106-7112.2003
-
Nair, P., Somasundaram, K. & Krishna, S. Activated Notch1 inhibits p53 induced apoptosis and sustains transformation by human papillomavirus type16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway. J.Virol. 77, 7106-7112 (2003). (Pubitemid 36666904)
-
(2003)
Journal of Virology
, vol.77
, Issue.12
, pp. 7106-7112
-
-
Nair, P.1
Somasundaram, K.2
Krishna, S.3
-
61
-
-
67449116604
-
Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells
-
Meurette, O. et al. Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells. Cancer Res. 69, 5015-5022 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 5015-5022
-
-
Meurette, O.1
-
62
-
-
78649363017
-
Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation
-
Wendorff, A.A. et al. Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation. Immunity 33, 671-684 (2010).
-
(2010)
Immunity
, vol.33
, pp. 671-684
-
-
Wendorff, A.A.1
-
63
-
-
33646415906
-
Survival signaling by Notch1: Mammalian target of rapamycin (mTOR)-dependent inhibition of p53
-
Mungamuri, S., Yang, X., Thor, A. & Somasundaram, K. Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53. Cancer Res. 66, 4715-4724 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 4715-4724
-
-
Mungamuri, S.1
Yang, X.2
Thor, A.3
Somasundaram, K.4
-
64
-
-
23844446044
-
Suppression of p53 by Notch in lymphomagenesis: Implications for initiation and regression
-
DOI 10.1158/0008-5472.CAN-05-1664
-
Beverly, L., Felsher, D. & Capobianco, A. Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression. Cancer Res. 65, 7159-7168 (2005). (Pubitemid 41161246)
-
(2005)
Cancer Research
, vol.65
, Issue.16
, pp. 7159-7168
-
-
Beverly, L.J.1
Felsher, D.W.2
Capobianco, A.J.3
-
65
-
-
53249103473
-
Notch-1 associates with IKKα and regulates IKK activity in cervical cancer cells
-
Song, L.L. et al. Notch-1 associates with IKKα and regulates IKK activity in cervical cancer cells. Oncogene 27, 5833-5844 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 5833-5844
-
-
Song, L.L.1
-
66
-
-
33846392694
-
Coexpression of Notch1 and NF-κB signaling pathway components in human cervical cancer progression
-
DOI 10.1016/j.ygyno.2006.08.054, PII S0090825806006901
-
Ramdass, B. et al. Coexpression of Notch1 and NF-κB signaling pathway components in human cervical cancer progression. Gynecol. Oncol. 104, 352-361 (2007). (Pubitemid 46135657)
-
(2007)
Gynecologic Oncology
, vol.104
, Issue.2
, pp. 352-361
-
-
Ramdass, B.1
Maliekal, T.T.2
Lakshmi, S.3
Rehman, M.4
Rema, P.5
Nair, P.6
Mukherjee, G.7
Reddy, B.K.M.8
Krishna, S.9
Radhakrishna Pillai, M.10
-
67
-
-
37549037911
-
Off the beaten pathway: The complex cross talk between Notch and NF-κB
-
Osipo, C., Golde, T.E., Osborne, B.A. & Miele, L.A. Off the beaten pathway: the complex cross talk between Notch and NF-κB. Lab. Invest. 88, 11-17 (2008).
-
(2008)
Lab. Invest.
, vol.88
, pp. 11-17
-
-
Osipo, C.1
Golde, T.E.2
Osborne, B.A.3
Miele, L.A.4
-
68
-
-
34648814084
-
Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision
-
DOI 10.1007/s00535-007-2087-z
-
Nakamura, T., Tsuchiya, K. & Watanabe, M. Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision. J.Gastroenterol. 42, 705-710 (2007). (Pubitemid 47456757)
-
(2007)
Journal of Gastroenterology
, vol.42
, Issue.9
, pp. 705-710
-
-
Nakamura, T.1
Tsuchiya, K.2
Watanabe, M.3
-
69
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
Bienz, M. & Clevers, H. Linking colorectal cancer to Wnt signaling. Cell 103, 311-320 (2000).
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
70
-
-
0029920515
-
Alteration of β-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients
-
Inomata, M., Ochiai, A., Akimoto, S., Kitano, S. & Hirohashi, S. Alteration of β-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients. Cancer Res. 56, 2213-2217 (1996). (Pubitemid 26119927)
-
(1996)
Cancer Research
, vol.56
, Issue.9
, pp. 2213-2217
-
-
Inomata, M.1
Ochiai, A.2
Akimoto, S.3
Kitano, S.4
Hirohashi, S.5
-
71
-
-
0034088858
-
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
-
DOI 10.1038/73448
-
Satoh, S. et al. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nature Genet. 24, 245-250 (2000). (Pubitemid 30132191)
-
(2000)
Nature Genetics
, vol.24
, Issue.3
, pp. 245-250
-
-
Satoh, S.1
Daigo, Y.2
Furukawa, Y.3
Kato, T.4
Miwa, N.5
Nishiwaki, T.6
Kawasoe, T.7
Ishiguro, H.8
Fujita, M.9
Tokino, T.10
Sasaki, Y.11
Imaoka, S.12
Murata, M.13
Shimano, T.14
Yamaoka, Y.15
Nakamura, Y.16
-
72
-
-
0030975671
-
Constitutive transcriptional activation by a β-catenin-Tcf complex in APC(-/-) colon carcinoma
-
DOI 10.1126/science.275.5307.1784
-
Korinek, V. et al. Constitutive transcriptional activation by a βcatenintcf complex in APC?/- colon carcinoma. Science 275, 1784-1787 (1997). (Pubitemid 27136714)
-
(1997)
Science
, vol.275
, Issue.5307
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
Van Wichen, D.4
De Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
73
-
-
10744229341
-
The Wnt Antagonist sFRP1 in Colorectal Tumorigenesis
-
DOI 10.1158/0008-5472.CAN-03-1346
-
Caldwell, G. et al. The Wnt antagonist sFRP1 in colorectal tumorigenesis. Cancer Res. 64, 883-888 (2004). (Pubitemid 38176888)
-
(2004)
Cancer Research
, vol.64
, Issue.3
, pp. 883-888
-
-
Caldwell, G.M.1
Jones, C.2
Gensberg, K.3
Jan, S.4
Hardy, R.G.5
Byrd, P.6
Chughtai, S.7
Wallis, Y.8
Matthews, G.M.9
Morton, D.G.10
-
74
-
-
12144291274
-
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
-
DOI 10.1038/ng1330
-
Suzuki, H. et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nature Genet. 36, 417-422 (2004). (Pubitemid 38437267)
-
(2004)
Nature Genetics
, vol.36
, Issue.4
, pp. 417-422
-
-
Suzuki, H.1
Watkins, D.N.2
Jair, K.-W.3
Schuebel, K.E.4
Markowitz, S.D.5
Chen, W.D.6
Pretlow, T.P.7
Yang, B.8
Akiyama, Y.9
Van Engeland, M.10
Toyota, M.11
Tokino, T.12
Hinoda, Y.13
Imai, K.14
Herman, J.G.15
Baylin, S.B.16
-
75
-
-
0035930967
-
WNT2B2 mRNA, up-regulated in primary gastric cancer, is a positive regulator of the WNT-β-catenin-TCF signaling pathway
-
DOI 10.1006/bbrc.2001.6076
-
Katoh, M., Kirikoshi, H., Terasaki, H. & Shiokawa, K. WNT2B2 mRNA, up-regulated in primary gastric cancer, is a positive regulator of the WNT- βcatenintCF signaling pathway. Biochem. Biophys. Res. Commun. 289, 1093-1098 (2001). (Pubitemid 34076303)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.289
, Issue.5
, pp. 1093-1098
-
-
Katoh, M.1
Kirikoshi, H.2
Terasaki, H.3
Shiokawa, K.4
-
76
-
-
0035656179
-
Expression of WNT14 and WNT14B mRNAs in human cancer, up-regulation of WNT14 by IFNγ and up-regulation of WNT14B by β-estradiol
-
Kirikoshi, H., Sekihara, H. & Katoh, M. Expression of WNT14 and WNT14B mRNAs in human cancer, up-regulation of WNT14 by IFNγ and up-regulation of WNT14B by β-estradiol. Int. J.Oncol. 19, 1221-1225 (2001).
-
(2001)
Int. J.Oncol.
, vol.19
, pp. 1221-1225
-
-
Kirikoshi, H.1
Sekihara, H.2
Katoh, M.3
-
77
-
-
2142746966
-
Up-regulation and overproduction of DVL-1, the human counterpart of the Drosophila dishevelled gene, in cervical squamous cell carcinoma
-
Okino, K. et al. Up-regulation and overproduction of DVL-1, the human counterpart of the Drosophila dishevelled gene, in cervical squamous cell carcinoma. Oncol. Rep. 10, 1219-1223 (2003).
-
(2003)
Oncol. Rep.
, vol.10
, pp. 1219-1223
-
-
Okino, K.1
-
78
-
-
0036483577
-
Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT - β-catenin TCF signaling pathway
-
Terasaki, H., Saitoh, T., Shiokawa, K. & Katoh, M. Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT - β-catenin TCF signaling pathway. Int. J.Mol. Med. 9, 107-112 (2002).
-
(2002)
Int. J.Mol. Med.
, vol.9
, pp. 107-112
-
-
Terasaki, H.1
Saitoh, T.2
Shiokawa, K.3
Katoh, M.4
-
79
-
-
36849014861
-
An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/β-catenin signaling
-
Bjorklund, P., Akerstrom, G. & Westin, G. An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/β-catenin signaling. PLoS Med. 4, e328 (2007).
-
(2007)
PLoS Med.
, vol.4
-
-
Bjorklund, P.1
Akerstrom, G.2
Westin, G.3
-
80
-
-
20544460148
-
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
DOI 10.1038/nature03659
-
van Es, J. et al. Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435, 959-963 (2005). (Pubitemid 40896322)
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 959-963
-
-
Van Es, J.H.1
Van Gijn, M.E.2
Riccio, O.3
Van Den Born, M.4
Vooijs, M.5
Begthel, H.6
Cozijnsen, M.7
Robine, S.8
Winton, D.J.9
Radtke, F.10
Clevers, H.11
-
81
-
-
0029670476
-
Interaction between Wingless and Notch signaling pathways mediated by dishevelled
-
Axelrod, J., Matsuno, K., Artavanis-Tsakonas, S. & Perrimon, N. Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science 271, 1826-1832 (1996).
-
(1996)
Science
, vol.271
, pp. 1826-1832
-
-
Axelrod, J.1
Matsuno, K.2
Artavanis-Tsakonas, S.3
Perrimon, N.4
-
82
-
-
0027996069
-
Notch is required for wingless signaling in the epidermis of Drosophila
-
DOI 10.1016/0092-8674(94)90195-3
-
Couso, J. & Martinez Arias, A. Notch is required for wingless signaling in the epidermis of Drosophila. Cell 79, 259-272 (1994). (Pubitemid 24324916)
-
(1994)
Cell
, vol.79
, Issue.2
, pp. 259-272
-
-
Couso, J.P.1
Arias, A.M.2
-
83
-
-
0347765662
-
Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development
-
DOI 10.1242/dev.00904
-
Giraldez, A. & Cohen, S. Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development. Development 130, 6533-6543 (2003). (Pubitemid 38088853)
-
(2003)
Development
, vol.130
, Issue.26
, pp. 6533-6543
-
-
Giraldez, A.J.1
Cohen, S.M.2
-
84
-
-
58549108259
-
β-catenin modulates the level and transcriptional activity of Notch1/NICD through its direct interaction
-
Jin, Y. et al. β-catenin modulates the level and transcriptional activity of Notch1/NICD through its direct interaction. Biochim. Biophys. Acta 1793, 290-299 (2009).
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, pp. 290-299
-
-
Jin, Y.1
-
85
-
-
34548708035
-
Mastermind-like 1 is a specific coactivator of β-catenin transcription activation and is essential for colon carcinoma cell survival
-
DOI 10.1158/0008-5472.CAN-07-1720
-
Alves-Guerra, M., Ronchini, C. & Capobianco, A. Mastermind-like 1 is a specific coactivator of β-catenin transcription activation and is essential for colon carcinoma cell survival. Cancer Res. 67, 8690-8698 (2007). (Pubitemid 47437444)
-
(2007)
Cancer Research
, vol.67
, Issue.18
, pp. 8690-8698
-
-
Alves-Guerra, M.-C.1
Ronchini, C.2
Capobianco, A.J.3
-
86
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
DOI 10.1038/ng1099
-
Nicolas, M. et al. Notch1 functions as a tumor suppressor in mouse skin. Nature Genet. 33, 416-421 (2003). (Pubitemid 36278861)
-
(2003)
Nature Genetics
, vol.33
, Issue.3
, pp. 416-421
-
-
Nicolas, M.1
Wolfer, A.2
Raj, K.3
Kummer, J.A.4
Mill, P.5
Van Noort, M.6
Hui, C.-C.7
Clevers, H.8
Dotto, G.P.9
Radtke, F.10
-
87
-
-
22344436360
-
WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
-
DOI 10.1101/gad.341405
-
Devgan, V., Mammucari, C., Millar, S.E., Brisken, C. & Dotto, G.P. p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev. 19, 1485-1495 (2005). (Pubitemid 41003015)
-
(2005)
Genes and Development
, vol.19
, Issue.12
, pp. 1485-1495
-
-
Devgan, V.1
Mammucari, C.2
Millar, S.E.3
Brisken, C.4
Dotto, G.P.5
-
88
-
-
57749116315
-
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia
-
De La, O.J. et al. Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia. Proc. Natl Acad. Sci. USA 105, 18907-18912 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 18907-18912
-
-
De La, O.J.1
-
89
-
-
67649313759
-
Notch and Kras in pancreatic cancer: At the crossroads of mutation, differentiation and signaling
-
De La, O.J. & Murtaugh, L.C. Notch and Kras in pancreatic cancer: at the crossroads of mutation, differentiation and signaling. Cell Cycle 8, 1860-1864 (2009).
-
(2009)
Cell Cycle
, vol.8
, pp. 1860-1864
-
-
De La, O.J.1
Murtaugh, L.C.2
-
90
-
-
0036734148
-
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells
-
DOI 10.1038/nm754
-
Weijzen, S. et al. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nature Med. 8, 979-986 (2002). (Pubitemid 35033702)
-
(2002)
Nature Medicine
, vol.8
, Issue.9
, pp. 979-986
-
-
Weijzen, S.1
Rizzo, P.2
Braid, M.3
Vaishnav, R.4
Jonkheer, S.M.5
Zlobin, A.6
Osborne, B.A.7
Gottipati, S.8
Aster, J.C.9
Hahn, W.C.10
Rudolf, M.11
Siziopikou, K.12
Martin Kast, W.13
Miele, L.14
-
91
-
-
8844262579
-
Periodic Delta-like 4 expression in developing retinal arteries
-
DOI 10.1016/j.modgep.2004.05.004, PII S1567133X04000821
-
Claxton, S. & Fruttiger, M. Periodic Delta-like 4 expression in developing retinal arteries. Gene Expr. Patterns 5, 123-127 (2004). (Pubitemid 39529808)
-
(2004)
Gene Expression Patterns
, vol.5
, Issue.1
, pp. 123-127
-
-
Claxton, S.1
Fruttiger, M.2
-
92
-
-
33847046849
-
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
-
DOI 10.1038/nature05571, PII NATURE05571
-
Hellstrom, M. et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 445, 776-780 (2007). (Pubitemid 46279716)
-
(2007)
Nature
, vol.445
, Issue.7129
, pp. 776-780
-
-
Hellstrom, M.1
Phng, L.-K.2
Hofmann, J.J.3
Wallgard, E.4
Coultas, L.5
Lindblom, P.6
Alva, J.7
Nilsson, A.-K.8
Karlsson, L.9
Gaiano, N.10
Yoon, K.11
Rossant, J.12
Iruela-Arispe, M.L.13
Kalen, M.14
Gerhardt, H.15
Betsholtz, C.16
-
93
-
-
33847607880
-
The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching
-
DOI 10.1073/pnas.0611177104
-
Suchting, S. et al. The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching. Proc. Natl Acad. Sci. USA 104, 3225-3230 (2007). (Pubitemid 46364141)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.9
, pp. 3225-3230
-
-
Suchting, S.1
Freitas, C.2
Le Noble, F.3
Benedito, R.4
Breant, C.5
Duarte, A.6
Eichmann, A.7
-
94
-
-
0035753241
-
Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis
-
Mailhos, C. et al. Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation 69, 135-144 (2001). (Pubitemid 33755062)
-
(2001)
Differentiation
, vol.69
, Issue.2-3
, pp. 135-144
-
-
Mailhos, C.1
Modlich, U.2
Lewis, J.3
Harris, A.4
Bicknell, R.5
Ish-Horowicz, D.6
-
95
-
-
33748359703
-
Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer
-
DOI 10.1158/1078-0432.CCR-06-0285
-
Patel, N. et al. Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer. Clin. Cancer Res. 12, 4836-4844 (2006). (Pubitemid 44338568)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.16
, pp. 4836-4844
-
-
Patel, N.S.1
Dobbie, M.S.2
Rochester, M.3
Steers, G.4
Poulsom, R.5
Le Monnier, K.6
Cranston, D.W.7
Li, J.-L.8
Harris, A.L.9
-
96
-
-
34247539127
-
The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth
-
DOI 10.1038/nrc2130, PII NRC2130
-
Thurston, G., Noguera-Troise, I. & Yancopoulos, G. The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth. Nature Rev. Cancer 7, 327-331 (2007). (Pubitemid 46652486)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.5
, pp. 327-331
-
-
Thurston, G.1
Noguera-Troise, I.2
Yancopoulos, G.D.3
-
97
-
-
25444506836
-
Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
-
DOI 10.1158/0008-5472.CAN-05-1208
-
Patel, N. et al. Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function. Cancer Res. 65, 8690-8697 (2005). (Pubitemid 41377356)
-
(2005)
Cancer Research
, vol.65
, Issue.19
, pp. 8690-8697
-
-
Patel, N.S.1
Li, J.-L.2
Generali, D.3
Poulsom, R.4
Cranston, D.W.5
Harris, A.L.6
-
98
-
-
33845877157
-
Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
-
DOI 10.1038/nature05355, PII NATURE05355
-
Noguera-Troise, I. et al. Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis. Nature 444, 1032-1037 (2006). (Pubitemid 46018516)
-
(2006)
Nature
, vol.444
, Issue.7122
, pp. 1032-1037
-
-
Noguera-Troise, I.1
Daly, C.2
Papadopoulos, N.J.3
Coetzee, S.4
Boland, P.5
Gale, N.W.6
Chieh Lin, H.7
Yancopoulos, G.D.8
Thurston, G.9
-
99
-
-
66449123068
-
The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis
-
Benedito, R. et al. The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell 137, 1124-1135 (2009).
-
(2009)
Cell
, vol.137
, pp. 1124-1135
-
-
Benedito, R.1
-
100
-
-
0030756962
-
Fringe modulates Notch-ligand interactions
-
DOI 10.1038/43191
-
Panin, V.M., Papayannopoulos, V., Wilson, R. & Irvine, K.D. Fringe modulates Notch-ligand interactions. Nature 387, 908-912 (1997). (Pubitemid 27289592)
-
(1997)
Nature
, vol.387
, Issue.6636
, pp. 908-912
-
-
Panin, V.M.1
Papayannopoulos, V.2
Wilson, R.3
Irvine, K.D.4
-
101
-
-
67749104045
-
Differential regulation of transforming growth factor β signaling pathways by Notch in human endothelial cells
-
Fu, Y. et al. Differential regulation of transforming growth factor β signaling pathways by Notch in human endothelial cells. J.Biol. Chem. 284, 19452-19462 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 19452-19462
-
-
Fu, Y.1
-
102
-
-
10744231139
-
Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells
-
DOI 10.1038/sj.emboj.7600065
-
Itoh, F. et al. Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells. EMBO J. 23, 541-551 (2004). (Pubitemid 38282386)
-
(2004)
EMBO Journal
, vol.23
, Issue.3
, pp. 541-551
-
-
Itoh, F.1
Itoh, S.2
Goumans, M.J.3
Valdimarsdottir, G.4
Iso, T.5
Dotto, G.P.6
Hamamori, Y.7
Kedes, L.8
Kato, M.9
Ten Dijke, P.10
-
103
-
-
0344845003
-
Epithelial-mesenchymal transitions in development and pathologies
-
DOI 10.1016/j.ceb.2003.10.006
-
Thiery, J.P. Epithelial-mesenchymal transitions in development and pathologies. Curr. Opin. Cell Biol. 15, 740-746 (2003). (Pubitemid 37487967)
-
(2003)
Current Opinion in Cell Biology
, vol.15
, Issue.6
, pp. 740-746
-
-
Thiery, J.P.1
-
104
-
-
36549010842
-
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
-
DOI 10.1084/jem.20071082
-
Leong, K. et al. Jagged1 imediated Notch activation induces epithelialto imesenchymal transition through Slug-induced repression of E-cadherin. J.Exp. Med. 204, 2935-2948 (2007). (Pubitemid 350179562)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.12
, pp. 2935-2948
-
-
Leong, K.G.1
Niessen, K.2
Kulic, I.3
Raouf, A.4
Eaves, C.5
Pollet, I.6
Karsan, A.7
-
105
-
-
75549083984
-
Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion
-
Chen, J., Imanaka, N. & Griffin, J.D. Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion. Br. J.Cancer 102, 351-360 (2010).
-
(2010)
Br. J.Cancer
, vol.102
, pp. 351-360
-
-
Chen, J.1
Imanaka, N.2
Griffin, J.D.3
-
106
-
-
44049090235
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
-
DOI 10.1073/pnas.0802047105
-
Sahlgren, C., Gustafsson, M.V., Jin, S., Poellinger, L. & Lendahl, U. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc. Natl Acad. Sci. USA 105, 6392-6397 (2008). (Pubitemid 351758356)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.17
, pp. 6392-6397
-
-
Sahlgren, C.1
Gustafsson, M.V.2
Jin, S.3
Poellinger, L.4
Lendahl, U.5
-
107
-
-
1842524153
-
Integration of TGF-β/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition
-
DOI 10.1038/sj.emboj.7600069
-
Zavadil, J., Cermak, L., Soto-Nieves, N. & Bottinger, E.P. Integration of TGF-β/Smad and Jagged1/Notch signalling in epithelialto imesenchymal transition. EMBO J. 23, 1155-1165 (2004). (Pubitemid 38436879)
-
(2004)
EMBO Journal
, vol.23
, Issue.5
, pp. 1155-1165
-
-
Zavadil, J.1
Cermak, L.2
Soto-Nieves, N.3
Bottinger, E.P.4
-
108
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
DOI 10.1016/j.cell.2008.03.027, PII S0092867408004443
-
Mani, S. et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133, 704-715 (2008). (Pubitemid 351636299)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.-J.3
Eaton, E.Ng.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
109
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
DOI 10.1038/367645a0
-
Lapidot, T. et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367, 645-648 (1994). (Pubitemid 24067706)
-
(1994)
Nature
, vol.367
, Issue.6464
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
Minden, M.7
Paterson, B.8
Caligiuri, M.A.9
Dick, J.E.10
-
110
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
DOI 10.1038/nm0797-730
-
Bonnet, D. & Dick, J. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nature Med. 3, 730-737 (1997). (Pubitemid 27298715)
-
(1997)
Nature Medicine
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
111
-
-
70349123829
-
The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells
-
Cicalese, A. et al. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. Cell 138, 1083-1095 (2009).
-
(2009)
Cell
, vol.138
, pp. 1083-1095
-
-
Cicalese, A.1
-
112
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
DOI 10.1073/pnas.0530291100
-
Al-Hajj, M., Wicha, M., Benito-Hernandez, A., Morrison, S. & Clarke, M. Prospective identification of tumorigenic breast cancer cells. Proc. Natl Acad. Sci. USA 100, 3983-3988 (2003). (Pubitemid 36418143)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
113
-
-
77954238710
-
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
-
Boiko, A.D. et al. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature 466, 133-137 (2010).
-
(2010)
Nature
, vol.466
, pp. 133-137
-
-
Boiko, A.D.1
-
114
-
-
45549100014
-
Pancreatic cancer stem cells
-
Lee, C., Dosch, J. & Simeone, D. Pancreatic cancer stem cells. J.Clin. Oncol. 26, 2806-2812 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2806-2812
-
-
Lee, C.1
Dosch, J.2
Simeone, D.3
-
115
-
-
45549091414
-
Prostate cancer stem cells: A new target for therapy
-
Maitland, N. & Collins, A. Prostate cancer stem cells: a new target for therapy. J.Clin. Oncol. 26, 2862-2870 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2862-2870
-
-
Maitland, N.1
Collins, A.2
-
116
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
DOI 10.1038/nature05372, PII NATURE05372
-
O'Brien, C., Pollett, A., Gallinger, S. & Dick, J. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445, 106-110 (2007). (Pubitemid 46067310)
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
117
-
-
45549097925
-
Cancer stem cells and the ontogeny of lung cancer
-
Peacock, C. & Watkins, D. Cancer stem cells and the ontogeny of lung cancer. J.Clin. Oncol. 26, 2883-2889 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2883-2889
-
-
Peacock, C.1
Watkins, D.2
-
118
-
-
45549096553
-
Cancer stem cells in head and neck squamous cell cancer
-
Prince, M. & Ailles, L. Cancer stem cells in head and neck squamous cell cancer. J.Clin. Oncol. 26, 2871-2875 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2871-2875
-
-
Prince, M.1
Ailles, L.2
-
119
-
-
45549084904
-
Liver cancer stem cells
-
Sell, S. & Leffert, H. Liver cancer stem cells. J.Clin. Oncol. 26, 2800-2805 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2800-2805
-
-
Sell, S.1
Leffert, H.2
-
120
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh, S. et al. Identification of a cancer stem cell in human brain tumors. Cancer Res. 63, 5821-5828 (2003). (Pubitemid 37187480)
-
(2003)
Cancer Research
, vol.63
, Issue.18
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
Dirks, P.B.7
-
121
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
DOI 10.1038/nature05236, PII NATURE05236
-
Bao, S. et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444, 756-760 (2006). (Pubitemid 44949604)
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
122
-
-
16844368698
-
Tumour stem cells and drug resistance
-
DOI 10.1038/nrc1590
-
Dean, M., Fojo, T. & Bates, S. Tumour stem cells and drug resistance. Nature Rev. Cancer 5, 275-284 (2005). (Pubitemid 40488633)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.4
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
123
-
-
33748051406
-
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
-
DOI 10.1158/0008-5472.CAN-06-1010
-
Bao, S. et al. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res. 66, 7843-7848 (2006). (Pubitemid 44299144)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 7843-7848
-
-
Bao, S.1
Wu, Q.2
Sathornsumetee, S.3
Hao, Y.4
Li, Z.5
Hjelmeland, A.B.6
Shi, Q.7
McLendon, R.E.8
Bigner, D.D.9
Rich, J.N.10
-
124
-
-
78649845933
-
Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate
-
Pistollato, F. et al. Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate. Stem Cells 28, 1918-1929 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 1918-1929
-
-
Pistollato, F.1
-
125
-
-
0033694305
-
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
-
Varnum-Finney, B. et al. Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling. Nature Med. 6, 1278-1281 (2000).
-
(2000)
Nature Med.
, vol.6
, pp. 1278-1281
-
-
Varnum-Finney, B.1
-
126
-
-
18944375734
-
Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells
-
Dontu, G. et al. Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells. Breast Cancer Res. 6, R605-R615 (2004).
-
(2004)
Breast Cancer Res.
, vol.6
-
-
Dontu, G.1
-
127
-
-
36248953716
-
Mammary stem cells and breast cancer - Role of notch signalling
-
DOI 10.1007/s12015-007-0023-5, PII SCR32169
-
Farnie, G. & Clarke, R. Mammary stem cells and breast cancer-role of Notch signalling. Stem Cell Rev. 3, 169-175 (2007). (Pubitemid 350129719)
-
(2007)
Stem Cell Reviews
, vol.3
, Issue.2
, pp. 169-175
-
-
Farnie, G.1
Clarke, R.B.2
-
128
-
-
34247581697
-
Novel cell culture technique for primary ductal carcinoma in situ: Role of notch and epidermal growth Factor Receptor Signaling Pathways
-
DOI 10.1093/jnci/djk133
-
Farnie, G. et al. Novel cell culture technique for primary ductal carcinoma insitu: role of Notch and epidermal growth factor receptor signaling pathways. J.Natl Cancer Inst. 99, 616-627 (2007). (Pubitemid 47073543)
-
(2007)
Journal of the National Cancer Institute
, vol.99
, Issue.8
, pp. 616-627
-
-
Farnie, G.1
Clarke, R.B.2
Spence, K.3
Pinnock, N.4
Brennan, K.5
Anderson, N.G.6
Bundred, N.J.7
-
129
-
-
36949031706
-
Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells
-
DOI 10.1007/s11010-007-9589-0
-
Zhang, X. et al. Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells. Mol. Cell. Biochem. 307, 101-108 (2008). (Pubitemid 350238652)
-
(2008)
Molecular and Cellular Biochemistry
, vol.307
, Issue.1-2
, pp. 101-108
-
-
Zhang, X.-P.1
Zheng, G.2
Zou, L.3
Liu, H.-L.4
Hou, L.-H.5
Zhou, P.6
Yin, D.-D.7
Zheng, Q.-J.8
Liang, L.9
Zhang, S.-Z.10
Feng, L.11
Yao, L.-B.12
Yang, A.-P.13
Han, H.14
Chen, J.-Y.15
-
130
-
-
0036205049
-
Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells
-
DOI 10.1101/gad.975202
-
Hitoshi, S. et al. Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes Dev. 16, 846-858 (2002). (Pubitemid 34280108)
-
(2002)
Genes and Development
, vol.16
, Issue.7
, pp. 846-858
-
-
Hitoshi, S.1
Alexson, T.2
Tropepe, V.3
Donoviel, D.4
Elia, A.J.5
Nye, J.S.6
Conlon, R.A.7
Mak, T.W.8
Bernstein, A.9
Van Der Kooy, D.10
-
131
-
-
3543086157
-
Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling
-
DOI 10.1101/gad.1208404
-
Hitoshi, S. et al. Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling. Genes Dev. 18, 1806-1811 (2004). (Pubitemid 39025091)
-
(2004)
Genes and Development
, vol.18
, Issue.15
, pp. 1806-1811
-
-
Hitoshi, S.1
Seaberg, R.M.2
Koscik, C.3
Alexson, T.4
Kusunoki, S.5
Kanazawa, I.6
Tsuji, S.7
Van Der Kooy, D.8
-
132
-
-
0033993524
-
The bHLH gene Hes1 as a repressor of the neuronal commitment of CNS stem cells
-
Nakamura, Y. et al. The bHLH gene hes1 as a repressor of the neuronal commitment of CNS stem cells. J.Neurosci. 20, 283-293 (2000). (Pubitemid 30220516)
-
(2000)
Journal of Neuroscience
, vol.20
, Issue.1
, pp. 283-293
-
-
Nakamura, Y.1
Sakakibara, S.-I.2
Miyata, T.3
Ogawa, M.4
Shimazaki, T.5
Weiss, S.6
Kageyama, R.7
Okano, H.8
-
133
-
-
75349105363
-
Notch pathway blockade depletes CD133?positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
-
Fan, X. et al. Notch pathway blockade depletes CD133?positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells 28, 5-16 (2009).
-
(2009)
Stem Cells
, vol.28
, pp. 5-16
-
-
Fan, X.1
-
134
-
-
58349091690
-
γ-secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity
-
Meng, R.D. et al. γ-secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity. Cancer Res. 69, 573-582 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 573-582
-
-
Meng, R.D.1
-
135
-
-
38149142478
-
Expression of nuclear Notch3 in pancreatic adenocarcinomas is associated with adverse clinical features, and correlates with the expression of STAT3 and phosphorylated Akt
-
Doucas, H. et al. Expression of nuclear Notch3 in pancreatic adenocarcinomas is associated with adverse clinical features, and correlates with the expression of STAT3 and phosphorylated Akt. J.Surg. Oncol. 97, 63-68 (2008).
-
(2008)
J. Surg. Oncol.
, vol.97
, pp. 63-68
-
-
Doucas, H.1
-
136
-
-
37349088615
-
γ-Secretase inhibitors enhance taxane-induced mitotic arrest and apoptosis in colon cancer cells
-
DOI 10.1053/j.gastro.2007.10.008, PII S0016508507018070
-
Akiyoshi, T. et al. γ-secretase inhibitors enhance taxane-induced mitotic arrest and apoptosis in colon cancer cells. Gastroenterology 134, 131-144 (2008). (Pubitemid 350309314)
-
(2008)
Gastroenterology
, vol.134
, Issue.1
, pp. 131-144
-
-
Akiyoshi, T.1
Nakamura, M.2
Yanai, K.3
Nagai, S.4
Wada, J.5
Koga, K.6
Nakashima, H.7
Sato, N.8
Tanaka, M.9
Katano, M.10
-
137
-
-
67650066781
-
Essential role of Notch signaling in apoptosis of human pancreatic tumoral cells mediated by exosomal nanoparticles
-
Ristorcelli, E., Beraud, E., Mathieu, S., Lombardo, D. & Verine, A. Essential role of Notch signaling in apoptosis of human pancreatic tumoral cells mediated by exosomal nanoparticles. Int. J.Cancer 125, 1016-1026 (2009).
-
(2009)
Int. J.Cancer
, vol.125
, pp. 1016-1026
-
-
Ristorcelli, E.1
Beraud, E.2
Mathieu, S.3
Lombardo, D.4
Verine, A.5
-
138
-
-
77749321234
-
Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways
-
Wang, Z. et al. Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways. J.Cell. Biochem. 109, 726-736 (2010).
-
(2010)
J. Cell. Biochem.
, vol.109
, pp. 726-736
-
-
Wang, Z.1
-
139
-
-
50649125794
-
ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor
-
Osipo, C. et al. ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor. Oncogene 27, 5019-5032 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 5019-5032
-
-
Osipo, C.1
-
140
-
-
74449091897
-
Notch-1 activates estrogen receptor-αdependent transcription via IKKα in breast cancer cells
-
Hao, L. et al. Notch-1 activates estrogen receptor-αdependent transcription via IKKα in breast cancer cells. Oncogene 29, 201-213 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 201-213
-
-
Hao, L.1
-
141
-
-
63849329353
-
A functional Notch-survivin gene signature in basal breast cancer
-
Lee, C.W. et al. A functional Notch-survivin gene signature in basal breast cancer. Breast Cancer Res. 10, R97 (2008).
-
(2008)
Breast Cancer Res.
, vol.10
-
-
Lee, C.W.1
-
142
-
-
48549085976
-
Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis
-
Lee, C.W., Raskett, C.M., Prudovsky, I. & Altieri, D.C. Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis. Cancer Res. 68, 5273-5281 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 5273-5281
-
-
Lee, C.W.1
Raskett, C.M.2
Prudovsky, I.3
Altieri, D.C.4
-
143
-
-
75349108271
-
Notch promotes radioresistance of glioma stem cells
-
Wang, J. et al. Notch promotes radioresistance of glioma stem cells. Stem Cells 28, 17-28 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 17-28
-
-
Wang, J.1
-
144
-
-
77956294442
-
γ-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence
-
Gilbert, C.A., Daou, M.C., Moser, R.P. & Ross, A.H. γ-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence. Cancer Res. 70, 6870-6879 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 6870-6879
-
-
Gilbert, C.A.1
Daou, M.C.2
Moser, R.P.3
Ross, A.H.4
-
145
-
-
77952736684
-
Notch: Implications of endogenous inhibitors for therapy
-
Dikic, I. & Schmidt, M.H. Notch: implications of endogenous inhibitors for therapy. Bioessays 32, 481-487 (2010).
-
(2010)
Bioessays
, vol.32
, pp. 481-487
-
-
Dikic, I.1
Schmidt, M.H.2
-
146
-
-
77951139188
-
Therapeutic antibody targeting of individual Notch receptors
-
Wu, Y. et al. Therapeutic antibody targeting of individual Notch receptors. Nature 464, 1052-1057 (2010).
-
(2010)
Nature
, vol.464
, pp. 1052-1057
-
-
Wu, Y.1
-
147
-
-
77954215506
-
Notch signaling: Emerging molecular targets for cancer therapy
-
Yin, L., Velazquez, O.C. & Liu, Z.J. Notch signaling: emerging molecular targets for cancer therapy. Biochem. Pharmacol. 80, 690-701 (2010).
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 690-701
-
-
Yin, L.1
Velazquez, O.C.2
Liu, Z.J.3
-
148
-
-
76549084826
-
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor
-
Harrison, H. et al. Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor. Cancer Res. 70, 709-718 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 709-718
-
-
Harrison, H.1
-
149
-
-
77955827414
-
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma
-
Mazur, P.K. et al. Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma. Proc. Natl Acad. Sci. USA 107, 13438-13443 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 13438-13443
-
-
Mazur, P.K.1
-
150
-
-
0037313331
-
T(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
-
DOI 10.1038/ng1083
-
Tonon, G. et al. t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway. Nature Genet. 33, 208-213 (2003). (Pubitemid 36177076)
-
(2003)
Nature Genetics
, vol.33
, Issue.2
, pp. 208-213
-
-
Tonon, G.1
Modi, S.2
Wu, L.3
Kubo, A.4
Coxon, A.B.5
Komiya, T.6
O'Neil, K.7
Stover, K.8
El-Naggar, A.9
Griffin, J.D.10
Kirsch, I.R.11
Kaye, F.J.12
-
151
-
-
0346725846
-
Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors
-
DOI 10.1016/j.yexcr.2003.09.007
-
Enlund, F. et al. Altered Notch signaling resulting from expression of a WAMTP1 imAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors. Exp. Cell Res. 292, 21-28 (2004). (Pubitemid 38058260)
-
(2004)
Experimental Cell Research
, vol.292
, Issue.1
, pp. 21-28
-
-
Enlund, F.1
Behboudi, A.2
Andren, Y.3
Oberg, C.4
Lendahl, U.5
Mark, J.6
Stenman, G.7
-
152
-
-
67549102534
-
Mucoepidermoid carcinoma of the cervix: Another tumor with the t(11;19)-associated CRTC1 imAML2 gene fusion
-
Lennerz, J.K., Perry, A., Mills, J.C., Huettner, P.C. & Pfeifer, J.D. Mucoepidermoid carcinoma of the cervix: another tumor with the t(11;19)-associated CRTC1 imAML2 gene fusion. Am. J.Surg. Pathol. 33, 835-843 (2009).
-
(2009)
Am. J.Surg. Pathol.
, vol.33
, pp. 835-843
-
-
Lennerz, J.K.1
Perry, A.2
Mills, J.C.3
Huettner, P.C.4
Pfeifer, J.D.5
-
153
-
-
17044384692
-
Clear cell hidradenoma of the skin - A third tumor type with a t(11;19)-associated TORCI-MAML2 gene fusion
-
DOI 10.1002/gcc.20168
-
Behboudi, A. et al. Clear cell hidradenoma of the skin-A third tumor type with a t(11;19)-associated TORC1 imAML2 gene fusion. Genes Chromosomes Cancer 43, 202-205 (2005). (Pubitemid 40570740)
-
(2005)
Genes Chromosomes and Cancer
, vol.43
, Issue.2
, pp. 202-205
-
-
Behboudi, A.1
Winnes, M.2
Gorunova, L.3
Van Den Oord, J.J.4
Mertens, F.5
Enlund, F.6
Stenman, G.7
-
154
-
-
70349527902
-
Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling
-
Martinez, A.M. et al. Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling. Nature Genet. 41, 1076-1082 (2009).
-
(2009)
Nature Genet.
, vol.41
, pp. 1076-1082
-
-
Martinez, A.M.1
-
155
-
-
31444452060
-
Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing
-
DOI 10.1038/nature04376, PII NATURE04376
-
Ferres-Marco, D. et al. Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing. Nature 439, 430-436 (2006). (Pubitemid 43152828)
-
(2006)
Nature
, vol.439
, Issue.7075
, pp. 430-436
-
-
Ferres-Marco, D.1
Gutierrez-Garcia, I.2
Vallejo, D.M.3
Bolivar, J.4
Gutierrez-Avino, F.J.5
Dominguez, M.6
-
156
-
-
70349183714
-
Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing
-
Moshkin, Y.M. et al. Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing. Mol. Cell 35, 782-793 (2009).
-
(2009)
Mol. Cell
, vol.35
, pp. 782-793
-
-
Moshkin, Y.M.1
-
157
-
-
34848825012
-
Gene-specific targeting of the histone chaperone Asf1 to mediate silencing
-
DOI 10.1016/j.devcel.2007.08.021, PII S1534580707003401
-
Goodfellow, H. et al. Gene-specific targeting of the histone chaperone Asf1 to mediate silencing. Dev. Cell 13, 593-600 (2007). (Pubitemid 47500809)
-
(2007)
Developmental Cell
, vol.13
, Issue.4
, pp. 593-600
-
-
Goodfellow, H.1
Krejci, A.2
Moshkin, Y.3
Verrijzer, C.P.4
Karch, F.5
Bray, S.J.6
-
158
-
-
18544373198
-
Skeletrophin, a novel ubiquitin ligase to the intracellular region of Jagged-2, is aberrantly expressed in multiple myeloma
-
Takeuchi, T., Adachi, Y. & Ohtsuki, Y. Skeletrophin, a novel ubiquitin ligase to the intracellular region of Jagged?2, is aberrantly expressed in multiple myeloma. Am. J.Pathol. 166, 1817-1826 (2005). (Pubitemid 40734404)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.6
, pp. 1817-1826
-
-
Takeuchi, T.1
Adachi, Y.2
Ohtsuki, Y.3
-
159
-
-
33750869288
-
A ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasion
-
DOI 10.1038/sj.onc.1209688, PII 1209688
-
Takeuchi, T., Adachi, Y., Sonobe, H., Furihata, M. & Ohtsuki, Y. A ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasion. Oncogene 25, 7059-7069 (2006). (Pubitemid 44722073)
-
(2006)
Oncogene
, vol.25
, Issue.53
, pp. 7059-7069
-
-
Takeuchi, T.1
Adachi, Y.2
Sonobe, H.3
Furihata, M.4
Ohtsuki, Y.5
-
160
-
-
0034791336
-
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation
-
DOI 10.1128/MCB.21.21.7403-7415.2001
-
Wu, G. et al. SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation. Mol. Cell. Biol. 21, 7403-7415 (2001). (Pubitemid 32953491)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.21
, pp. 7403-7415
-
-
Wu, G.1
Lyapina, S.2
Das, I.3
Li, J.4
Gurney, M.5
Pauley, A.6
Chui, I.7
Deshaies, R.J.8
Kitajewski, J.9
-
161
-
-
35148842479
-
FBXW7/hCDC4 is a general tumor suppressor in human cancer
-
DOI 10.1158/0008-5472.CAN-07-1320
-
Akhoondi, S. et al. FBXW7/hCDC4 is a general tumor suppressor in human cancer. Cancer Res. 67, 9006-9012 (2007). (Pubitemid 47535882)
-
(2007)
Cancer Research
, vol.67
, Issue.19
, pp. 9006-9012
-
-
Akhoondi, S.1
Sun, D.2
Von Der Lehr, N.3
Apostolidou, S.4
Klotz, K.5
Maljukova, A.6
Cepeda, D.7
Fiegl, H.8
Dofou, D.9
Marth, C.10
Mueller-Holzner, E.11
Corcoran, M.12
Dagnell, M.13
Nejad, S.Z.14
Nayer, B.N.15
Zali, M.R.16
Hansson, J.17
Egyhazi, S.18
Petersson, F.19
Sangfelt, P.20
Nordgren, H.21
Grander, D.22
Reed, S.I.23
Widschwendter, M.24
Sangfelt, O.25
Spruck, C.26
more..
-
162
-
-
65449128132
-
Somatic mutations of the CDC4 (FBXW7) gene in hereditary colorectal tumors
-
Miyaki, M. et al. Somatic mutations of the CDC4 (FBXW7) gene in hereditary colorectal tumors. Oncology 76, 430-434 (2009).
-
(2009)
Oncology
, vol.76
, pp. 430-434
-
-
Miyaki, M.1
-
163
-
-
36049019691
-
Kaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sel10 protein
-
DOI 10.1073/pnas.0703508104
-
Lan, K. et al. Kaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sel10 protein. Proc. Natl Acad. Sci. USA 104, 16287-16292 (2007). (Pubitemid 350099398)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.41
, pp. 16287-16292
-
-
Lan, K.1
Verma, S.C.2
Murakami, M.3
Bajaj, B.4
Kaul, R.5
Robertson, E.S.6
-
164
-
-
0037663379
-
Mammalian Numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain
-
DOI 10.1074/jbc.M302827200
-
McGill, M.A. & McGlade, C.J. Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain. J.Biol. Chem. 278, 23196-23203 (2003). (Pubitemid 36830386)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.25
, pp. 23196-23203
-
-
McGill, M.A.1
McGlade, C.J.2
-
165
-
-
7244250027
-
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
-
DOI 10.1083/jcb.200406140
-
Pece, S. et al. Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J.Cell Biol. 167, 215-221 (2004). (Pubitemid 39435065)
-
(2004)
Journal of Cell Biology
, vol.167
, Issue.2
, pp. 215-221
-
-
Pece, S.1
Serresi, M.2
Santolini, E.3
Capra, M.4
Hulleman, E.5
Galimberti, V.6
Zurrida, S.7
Maisonneuve, P.8
Viale, G.9
Di Fiore, P.P.10
-
166
-
-
38049046724
-
NUMB controls p53 tumour suppressor activity
-
Colaluca, I.N. et al. NUMB controls p53 tumour suppressor activity. Nature 451, 76-80 (2008).
-
(2008)
Nature
, vol.451
, pp. 76-80
-
-
Colaluca, I.N.1
-
167
-
-
0029047609
-
Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats
-
Matsuno, K., Diederich, R.J., Go, M.J., Blaumueller, C.M. & Artavanis-Tsakonas, S. Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development 121, 2633-2644 (1995).
-
(1995)
Development
, vol.121
, pp. 2633-2644
-
-
Matsuno, K.1
Diederich, R.J.2
Go, M.J.3
Blaumueller, C.M.4
Artavanis-Tsakonas, S.5
-
168
-
-
0031776415
-
Human deltex is a conserved regulator of Notch signalling
-
DOI 10.1038/ng0598-74
-
Matsuno, K. et al. Human deltex is a conserved regulator of Notch signalling. Nature Genet. 19, 74-78 (1998). (Pubitemid 28242028)
-
(1998)
Nature Genetics
, vol.19
, Issue.1
, pp. 74-78
-
-
Matsuno, K.1
Eastman, D.2
Mitsiades, T.3
Quinn, A.M.4
Carcanciu, M.L.5
Ordentlich, P.6
Kadesch, T.7
Artavanis-Tsakonas, S.8
-
169
-
-
18344388633
-
Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1
-
DOI 10.1016/S1074-7613(02)00271-6
-
Izon, D.J. et al. Deltex1 redirects lymphoid progenitors to the Bcell lineage by antagonizing Notch1. Immunity 16, 231-243 (2002). (Pubitemid 34211963)
-
(2002)
Immunity
, vol.16
, Issue.2
, pp. 231-243
-
-
Izon, D.J.1
Aster, J.C.2
He, Y.3
Weng, A.4
Karnell, F.G.5
Patriub, V.6
Xu, L.7
Bakkour, S.8
Rodriguez, C.9
Allman, D.10
Pear, W.S.11
-
170
-
-
0035977003
-
Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor
-
Yamamoto, N. et al. Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor. J.Biol. Chem. 276, 45031-45040 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45031-45040
-
-
Yamamoto, N.1
|