Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta; signaling

Oncogene

Volumn 24, Issue 34, 2005, Pages 5365-5374

  Sun, Youping ^a   Lowther, William ^a   Kato, Katsuaki ^a   Bianco, Caterina ^a   Kenney, Nicholas ^a   Strizzi, Luigi ^a   Raafat, Dina ^a   Hirota, Morihisa ^a   Khan, Nadia I ^a   Bargo, Sharon ^a   Jones, Brenda ^a   Salomon, David ^a   Callahan, Robert ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Notch4ICD; Smad3; TGF

Indexed keywords

ACTIVIN; GAMMA SECRETASE INHIBITOR; LUCIFERASE; NOTCH4 RECEPTOR; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; CELL SURFACE RECEPTOR; DNA BINDING PROTEIN; NOTCH RECEPTOR; NOTCH4 PROTEIN, HUMAN; NOTCH4 PROTEIN, MOUSE; ONCOPROTEIN; SMAD3 PROTEIN, HUMAN; SMAD3 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ARTICLE; BINDING AFFINITY; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; ENZYME ASSAY; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; BREAST TUMOR; CELL CULTURE; DRUG ANTAGONISM; FEMALE; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE;

MINK CELL FOCUS-FORMING VIRUS;

AMINO ACID MOTIFS; ANIMALS; BLOTTING, WESTERN; BREAST NEOPLASMS; DNA-BINDING PROTEINS; FEMALE; HUMANS; MICE; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 24044513994     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1208528     Document Type: Article

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