메뉴 건너뛰기




Volumn 69, Issue 2-3, 2001, Pages 135-144

Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis

Author keywords

Arterial endothelium; Cancer; Embryonic development; Vasculature

Indexed keywords

DLL4 PROTEIN, HUMAN; DROSOPHILA PROTEIN; GROWTH PROMOTOR; MEMBRANE PROTEIN; NOTCH PROTEIN, DROSOPHILA; NOTCH RECEPTOR; PLASMA PROTEIN; SIGNAL PEPTIDE;

EID: 0035753241     PISSN: 03014681     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-0436.2001.690207.x     Document Type: Article
Times cited : (267)

References (58)
  • 2
    • 0032807866 scopus 로고    scopus 로고
    • Expression of the mouse Delta1 gene during organogenesis and fetal development
    • Beckers, J., Clark, A., Wunsch, K., Hrabe De Angelis, M. and Gossler, A. (1999) Expression of the mouse Delta1 gene during organogenesis and fetal development. Mech Dev 84:165-168.
    • (1999) Mech Dev , vol.84 , pp. 165-168
    • Beckers, J.1    Clark, A.2    Wunsch, K.3    Hrabe De Angelis, M.4    Gossler, A.5
  • 3
    • 0029023204 scopus 로고
    • Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta
    • Bettenhausen, B., Hrabe de Angelis, M., Simon, D., Guenet, J.L. and Gossler, A. (1995) Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta. Development 121:2407-2418.
    • (1995) Development , vol.121 , pp. 2407-2418
    • Bettenhausen, B.1    Hrabe De Angelis, M.2    Simon, D.3    Guenet, J.L.4    Gossler, A.5
  • 4
    • 0032241789 scopus 로고    scopus 로고
    • Notch signalling in Drosophila: Three ways to use a pathway
    • Bray, S. (1998) Notch signalling in Drosophila: three ways to use a pathway. Semin Cell Dev Biol 9:591-597.
    • (1998) Semin Cell Dev Biol , vol.9 , pp. 591-597
    • Bray, S.1
  • 5
    • 0034011914 scopus 로고    scopus 로고
    • Notch signaling in T cell development
    • Deftos, M.L. and Bevan, M.J. (2000) Notch signaling in T cell development. Curr Opin Immunol 12:166-172.
    • (2000) Curr Opin Immunol , vol.12 , pp. 166-172
    • Deftos, M.L.1    Bevan, M.J.2
  • 6
    • 0026670590 scopus 로고
    • Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development
    • Del Amo, F.F., Smith, D.E., Swiatek, P.J., Gendron-Maguire, M., Greenspan, R.J., McMahon, A.P. and Gridley, T. (1992) Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development 115:737-744.
    • (1992) Development , vol.115 , pp. 737-744
    • Del Amo, F.F.1    Smith, D.E.2    Swiatek, P.J.3    Gendron-Maguire, M.4    Greenspan, R.J.5    McMahon, A.P.6    Gridley, T.7
  • 7
    • 0032890051 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Molecular and biological aspects
    • Ferrara, N. (1999) Vascular endothelial growth factor: molecular and biological aspects. Curr Top Microbiol Immunol 237:1-30.
    • (1999) Curr Top Microbiol Immunol , vol.237 , pp. 1-30
    • Ferrara, N.1
  • 8
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman, J. (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285:1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 9
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong, G.H., Rossant, J., Gertsenstein, M. and Breitman, M.L. (1995) Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376:66-70.
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 11
    • 0035865227 scopus 로고    scopus 로고
    • Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells
    • Gale, N.W., Baluk, P., Pan, L., Kwan, M., Holash, J., DeChiara, T.M., McDonald, D.M. and Yancopoulos, G.D. (2001) Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells. Dev Biol 230:151-160.
    • (2001) Dev Biol , vol.230 , pp. 151-160
    • Gale, N.W.1    Baluk, P.2    Pan, L.3    Kwan, M.4    Holash, J.5    DeChiara, T.M.6    McDonald, D.M.7    Yancopoulos, G.D.8
  • 12
    • 0033135876 scopus 로고    scopus 로고
    • Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development
    • Gale, N.W. and Yancopoulos, G.D. (1999) Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev 13:1055-1066.
    • (1999) Genes Dev , vol.13 , pp. 1055-1066
    • Gale, N.W.1    Yancopoulos, G.D.2
  • 13
    • 0033197535 scopus 로고    scopus 로고
    • Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development
    • Gerety, S.S., Wang, H.U., Chen, Z.F. and Anderson, D.J. (1999) Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol Cell 4:403-414.
    • (1999) Mol Cell , vol.4 , pp. 403-414
    • Gerety, S.S.1    Wang, H.U.2    Chen, Z.F.3    Anderson, D.J.4
  • 14
    • 0032055258 scopus 로고    scopus 로고
    • A role for Abl in Notch signaling
    • Giniger, E (1998) A role for Abl in Notch signaling. Neuron 20:667-681.
    • (1998) Neuron , vol.20 , pp. 667-681
    • Giniger, E.1
  • 15
    • 0032525964 scopus 로고    scopus 로고
    • LIN-12/Notch signaling: Lessons from worms and flies
    • Greenwald, I. (1998) LIN-12/Notch signaling: lessons from worms and flies. Genes Dev 12:1751-1762.
    • (1998) Genes Dev , vol.12 , pp. 1751-1762
    • Greenwald, I.1
  • 16
    • 0029062934 scopus 로고
    • Expression of a Delta homologue in prospective neurons in the chick
    • Henrique, D., Adam, J., Myat, A., Chitnis, A., Lewis, J. and Ish-Horowicz, D. (1995) Expression of a Delta homologue in prospective neurons in the chick. Nature 375:787-790.
    • (1995) Nature , vol.375 , pp. 787-790
    • Henrique, D.1    Adam, J.2    Myat, A.3    Chitnis, A.4    Lewis, J.5    Ish-Horowicz, D.6
  • 17
    • 0031240003 scopus 로고    scopus 로고
    • Maintenance of neuroepithelial progenitor cells by Delta-Notch signalling in the embryonic chick retina
    • Henrique, D., Hirsinger, E., Adam, J., Le Roux, I., Pourquie, O., Ish-Horowicz, D. and Lewis, J. (1997) Maintenance of neuroepithelial progenitor cells by Delta-Notch signalling in the embryonic chick retina. Curr Biol 7:661-670.
    • (1997) Curr Biol , vol.7 , pp. 661-670
    • Henrique, D.1    Hirsinger, E.2    Adam, J.3    Le Roux, I.4    Pourquie, O.5    Ish-Horowicz, D.6    Lewis, J.7
  • 18
    • 0021239705 scopus 로고
    • Endothelial proliferation in tumours and normal tissues: Continuous labelling studies
    • Hobson, B. and Denekamp, J. (1984) Endothelial proliferation in tumours and normal tissues: continuous labelling studies. Br J Cancer 49:405-413.
    • (1984) Br J Cancer , vol.49 , pp. 405-413
    • Hobson, B.1    Denekamp, J.2
  • 19
    • 0031747280 scopus 로고    scopus 로고
    • The next frontier of molecular medicine: Delivery of therapeutics
    • Jain, R.K. (1998) The next frontier of molecular medicine: delivery of therapeutics. Nat Med 4:655-657.
    • (1998) Nat Med , vol.4 , pp. 655-657
    • Jain, R.K.1
  • 23
    • 0033454716 scopus 로고    scopus 로고
    • Anticancer drug targets: Approaching angiogenesis
    • Keshet, E. and Ben-Sasson, S.A. (1999) Anticancer drug targets: approaching angiogenesis. J Clin Invest 104:1497-1501.
    • (1999) J Clin Invest , vol.104 , pp. 1497-1501
    • Keshet, E.1    Ben-Sasson, S.A.2
  • 25
    • 0032242705 scopus 로고    scopus 로고
    • Notch signalling and the control of cell fate choices in vertebrates
    • Lewis, J. (1998) Notch signalling and the control of cell fate choices in vertebrates. Semin Cell Dev Biol 9:583-589.
    • (1998) Semin Cell Dev Biol , vol.9 , pp. 583-589
    • Lewis, J.1
  • 27
    • 0033065890 scopus 로고    scopus 로고
    • The Notch pathway helps to pattern the tips of the Drosophila tracheal branches by selecting cell fates
    • Llimargas, M. (1999) The Notch pathway helps to pattern the tips of the Drosophila tracheal branches by selecting cell fates. Development 126:2355-2364.
    • (1999) Development , vol.126 , pp. 2355-2364
    • Llimargas, M.1
  • 32
    • 0029925224 scopus 로고    scopus 로고
    • A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis
    • Myat, A., Henrique, D., Ish-Horowicz, D. and Lewis, J. (1996) A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis. Dev Biol 174:233-247.
    • (1996) Dev Biol , vol.174 , pp. 233-247
    • Myat, A.1    Henrique, D.2    Ish-Horowicz, D.3    Lewis, J.4
  • 33
    • 0028807490 scopus 로고
    • Improved RNase protection assay for quantifying LDL-receptor mRNA; estimation of analytical imprecision and biological variance in peripheral blood mononuclear cells
    • Petersen, N.B., Larsen, L.K., Nissen, H., Jensen, L.G., Jensen, A., Hyltoft Petersen, P., Horder, M., Gregersen, N. and Kristiansen, K. (1995) Improved RNase protection assay for quantifying LDL-receptor mRNA; estimation of analytical imprecision and biological variance in peripheral blood mononuclear cells. Clin Chem 41:1605-1613.
    • (1995) Clin Chem , vol.41 , pp. 1605-1613
    • Petersen, N.B.1    Larsen, L.K.2    Nissen, H.3    Jensen, L.G.4    Jensen, A.5    Hyltoft Petersen, P.6    Horder, M.7    Gregersen, N.8    Kristiansen, K.9
  • 34
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    • Plate, K.H., Breier, G., Weich, H.A. and Risau, W. (1992) Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359:845-848.
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Risau, W.4
  • 35
    • 0034302945 scopus 로고    scopus 로고
    • Angiogenesis and vascular regression in the ovary
    • Plendl, J. (2000) Angiogenesis and vascular regression in the ovary. Anat Histol Embryol 29:257-266.
    • (2000) Anat Histol Embryol , vol.29 , pp. 257-266
    • Plendl, J.1
  • 36
    • 0033988735 scopus 로고    scopus 로고
    • Segmentation of the paraxial mesoderm and vertebrate somitogenesis
    • Pourquie, O. (2000) Segmentation of the paraxial mesoderm and vertebrate somitogenesis. Curr Top Dev Biol 47:81-105.
    • (2000) Curr Top Dev Biol , vol.47 , pp. 81-105
    • Pourquie, O.1
  • 39
    • 0033595679 scopus 로고    scopus 로고
    • Contact-dependent inhibition of cortical neurite growth mediated by notch signaling
    • Sestan, N., Artavanis-Tsakonas, S. and Rakic, P. (1999) Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science 286:741-6.
    • (1999) Science , vol.286 , pp. 741-746
    • Sestan, N.1    Artavanis-Tsakonas, S.2    Rakic, P.3
  • 40
    • 0033852168 scopus 로고    scopus 로고
    • Vascular developmental biology: Getting nervous
    • Shima, D.T. and Mailhos, C. (2000) Vascular developmental biology: getting nervous. Curr Opin Genet Dev 10:536-542.
    • (2000) Curr Opin Genet Dev , vol.10 , pp. 536-542
    • Shima, D.T.1    Mailhos, C.2
  • 41
    • 0035865049 scopus 로고    scopus 로고
    • Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization
    • Shin, D., Garcia-Cardena, G., Hayashi, S., Gerety, S., Asahara, T., Stavrakis, G., Isner, J., Folkman, J., Gimbrone, M.A. Jr. and Anderson, D.J. (2001) Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. Dev Biol 230:139-150.
    • (2001) Dev Biol , vol.230 , pp. 139-150
    • Shin, D.1    Garcia-Cardena, G.2    Hayashi, S.3    Gerety, S.4    Asahara, T.5    Stavrakis, G.6    Isner, J.7    Folkman, J.8    Gimbrone Jr., M.A.9    Anderson, D.J.10
  • 43
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki, D., Itin, A., Soffer, D. and Keshet, E. (1992) Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359:843-845.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 44
    • 0028329705 scopus 로고
    • A simple and efficient procedure for non-isotopic in situ hybridization to sectioned material
    • Strähle, U., Blader, P., Adam, J. and Ingham, P.W. (1994) A simple and efficient procedure for non-isotopic in situ hybridization to sectioned material. Trends Genet 10:75-76.
    • (1994) Trends Genet , vol.10 , pp. 75-76
    • Strähle, U.1    Blader, P.2    Adam, J.3    Ingham, P.W.4
  • 45
    • 0029206164 scopus 로고
    • Quantitative measurement of mRNA using the RNase protection assay
    • Tymms, M.J. (1995) Quantitative measurement of mRNA using the RNase protection assay. Methods Mol Biol 37:31-46.
    • (1995) Methods Mol Biol , vol.37 , pp. 31-46
    • Tymms, M.J.1
  • 46
    • 0035826844 scopus 로고    scopus 로고
    • Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium
    • Uyttendaele, H., Ho, J., Rossant, J. and Kitajewski, J. (2001) Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc Natl Acad Sci USA 98:5643-5648.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5643-5648
    • Uyttendaele, H.1    Ho, J.2    Rossant, J.3    Kitajewski, J.4
  • 47
    • 0030054646 scopus 로고    scopus 로고
    • Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene
    • Uyttendaele, H., Marazzi, G., Wu, G., Yan, Q., Sassoon, D. and Kitajewski, J. (1996) Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development 122:2251-2259.
    • (1996) Development , vol.122 , pp. 2251-2259
    • Uyttendaele, H.1    Marazzi, G.2    Wu, G.3    Yan, Q.4    Sassoon, D.5    Kitajewski, J.6
  • 49
    • 0025590174 scopus 로고
    • Blood flow, oxygen consumption and tissue oxygenation of human tumors
    • Vaupel, P., Kallinowski, F. and Okunieff, P. (1990) Blood flow, oxygen consumption and tissue oxygenation of human tumors. Adv Exp Med Biol 277:895-905.
    • (1990) Adv Exp Med Biol , vol.277 , pp. 895-905
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 50
    • 0032577446 scopus 로고    scopus 로고
    • Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
    • Wang, H.U., Chen, Z.F. and Anderson, D.J. (1998) Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93:741-753.
    • (1998) Cell , vol.93 , pp. 741-753
    • Wang, H.U.1    Chen, Z.F.2    Anderson, D.J.3
  • 51
    • 0028803128 scopus 로고
    • Gridlock, a localized heritable vascular patterning defect in the zebrafish
    • Weinstein, B.M., Stemple, D.L., Driever, W. and Fishman, M.C. (1995) Gridlock, a localized heritable vascular patterning defect in the zebrafish. Nat Med 1:1143-1147.
    • (1995) Nat Med , vol.1 , pp. 1143-1147
    • Weinstein, B.M.1    Stemple, D.L.2    Driever, W.3    Fishman, M.C.4
  • 52
    • 0034537599 scopus 로고    scopus 로고
    • The nuclear receptor co-repressor nrip1 (RIP140) is essential for female fertility
    • White, R., Leonardsson, G., Rosewell, I., Ann Jacobs, M., Milligan, S. and Parker, M. (2000) The nuclear receptor co-repressor nrip1 (RIP140) is essential for female fertility. Nat Med 6:1368-1374.
    • (2000) Nat Med , vol.6 , pp. 1368-1374
    • White, R.1    Leonardsson, G.2    Rosewell, I.3    Ann Jacobs, M.4    Milligan, S.5    Parker, M.6
  • 55
    • 0033832686 scopus 로고    scopus 로고
    • Inherited epithelial tumors of the kidney: Old and new diseases
    • Zbar, B. (2000) Inherited epithelial tumors of the kidney: old and new diseases. Semin Cancer Biol 10:313-318.
    • (2000) Semin Cancer Biol , vol.10 , pp. 313-318
    • Zbar, B.1
  • 56
    • 0028954492 scopus 로고
    • Enhancement of tumor growth and vascular density by transaction of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells
    • Zhang, H.T., Craft, P., Scott, P.A., Ziche, M., Weich, H.A., Harris, A.L. and Bicknell, R. (1995) Enhancement of tumor growth and vascular density by transaction of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells. J Natl Cancer Inst 87:213-219.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 213-219
    • Zhang, H.T.1    Craft, P.2    Scott, P.A.3    Ziche, M.4    Weich, H.A.5    Harris, A.L.6    Bicknell, R.7
  • 57
    • 0034629325 scopus 로고    scopus 로고
    • Gridlock, an HLH gene required for assembly of the aorta in zebrafish
    • Zhong, T.P., Rosenberg, M., Mohideen, M.A., Weinstein, B. and Fishman, M.C. (2000) gridlock, an HLH gene required for assembly of the aorta in zebrafish. Science 287:1820-1824.
    • (2000) Science , vol.287 , pp. 1820-1824
    • Zhong, T.P.1    Rosenberg, M.2    Mohideen, M.A.3    Weinstein, B.4    Fishman, M.C.5
  • 58
    • 0343661701 scopus 로고    scopus 로고
    • An antisense oligonucleotide to the notch ligand jagged enhances fibroblast growth factor-induced angiogenesis in vitro
    • Zimrin, A.B., Pepper, M.S., McMahon, G.A., Nguyen, F., Montesano, R. and Maciag, T. (1996) An antisense oligonucleotide to the notch ligand jagged enhances fibroblast growth factor-induced angiogenesis in vitro. J Biol Chem 271:32499-32502.
    • (1996) J Biol Chem , vol.271 , pp. 32499-32502
    • Zimrin, A.B.1    Pepper, M.S.2    McMahon, G.A.3    Nguyen, F.4    Montesano, R.5    Maciag, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.