Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate

Stem Cells

Volumn 28, Issue 11, 2010, Pages 1918-1929

  Pistollato, Francesca ^a   Rampazzo, Elena ^a   Persano, Luca ^a   Abbadi, Sara ^a   Frasson, Chiara ^a   Denaro, Luca ^a   D'Avella, Domenico ^a   Panchision, David M ^b   Puppa, Alessandro Della ^a   Scienza, Renato ^a   Basso, Giuseppe ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Cancer stem cells; Hypoxia; Hypoxia inducible factor 1 ; Medulloblastoma; Notch1

Indexed keywords

CD133 ANTIGEN; GAMMA SECRETASE INHIBITOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NESTIN; NOTCH RECEPTOR;

ARTICLE; CANCER STEM CELL; CELL EXPANSION; CELL FATE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; HYPOXIA; IN VITRO STUDY; MEDULLOBLASTOMA; NERVE CELL DIFFERENTIATION; OXYGEN TENSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANTIGENS, CD; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BRAIN NEOPLASMS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; GLYCOPROTEINS; HOMEODOMAIN PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; MEDULLOBLASTOMA; NEOPLASTIC STEM CELLS; NERVE TISSUE PROTEINS; PEPTIDES; POLYMERASE CHAIN REACTION; RECEPTOR, NOTCH1; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 78649845933     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.518     Document Type: Article

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