Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 24, 2006, Pages 9262-9267

  Klinakis, Apostolos ^a   Szaboks, Matthias ^a   Politi, Katerina ^a,c   Kiaris, Hippokratis ^b,d   Artavanis Tsakonas, Spyros ^b   Efstratiadis, Argiris ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Breast cancer; Mouse model

Indexed keywords

NOTCH1 RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CBF1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST ADENOCARCINOMA; BREAST CANCER; BREAST CARCINOGENESIS; BREAST CARCINOMA; BREAST EPITHELIUM; CANCER GROWTH; CANCER INCIDENCE; CANCER MODEL; CANCER REGRESSION; CONTROLLED STUDY; FEMALE; GENE INDUCTION; GENE TARGETING; GENETIC TRANSCRIPTION; IMMUNOHISTOCHEMISTRY; INVASIVE CARCINOMA; INVOLUTION; LACTATION; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; ONCOGENE MYC; PATHOGENESIS; PREGNANCY; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; BASE SEQUENCE; BREAST NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOPHENOTYPING; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PREGNANCY; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-MYC; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; SURVIVAL RATE; TRANSCRIPTION, GENETIC;

ANIMALIA; MOUSE MAMMARY TUMOR VIRUS; MUS MUSCULUS;

EID: 33745131039     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0603371103     Document Type: Article

References (33)

1. Artavanis-Tsakonas, S., Rand, M. D. & Lake, R. J. (1999) Science 284, 770-776.
2. Lai, E. C. (2004) Development (Cambridge, U.K.) 131, 965-973.
3. Honjo, T. (1996) Genes Cells 1, 1-9.
4. Radtke, F. & Raj, K. (2003) Nat. Rev. Cancer 3, 756-767.
5. Politi, K., Feirt, N. & Kitajewski, J. (2004) Semin. Cancer Biol. 14, 341-347.
6. Pear, W. S. & Aster, J. C. (2004) Curr. Opin. Hematol. 11, 426-433.
7. Weijzen, S., Rizzo, P., Braid, M., Vaishnav, R., Jonkheer, S. M., Zlobin, A., Osborne, B. A., Gottipati, S., Aster, J. C., Hahn, W. C., et al. (2002) Nat. Med. 8, 979-986.
8. Reedijk, M., Odorcic, S., Chang, L., Zhang, H., Miller, N., McCready, D. R., Lockwood, G. & Egan, S. E. (2005) Cancer Res. 65, 8530-8537.
9. Pece, S., Serresi, M., Santolini, E., Capra, M., Hulleman, E., Galimberti, V., Zurrida, S., Maisonneuve, P., Viale, G. & Di Fiore, P. P. (2004) J. Cell Biol. 167, 215-221.
10. Dievart, A., Beaulieu, N. & Jolicoeur, P. (1999) Oncogene 18, 5973-5981.
11. Callahan, R. & Egan, S. E. (2004) J. Mammary Gland Biol. Neoplasia 9, 145-163.
12. Kiaris, H., Politi, K., Grimm, L. M., Szabolcs, M., Fisher, P., Efstratiadis, A. & Artavanis-Tsakonas, S. (2004) Am. J. Pathol. 165, 695-705.
13. Guy, C. T., Cardiff, R. D. & Muller, W. J. (1992) Mol. Cell. Biol. 12, 954-961.
14. Stewart, T. A., Pattengale, P. K. & Leder, P. (1984) Cell 38, 627-637.
15. Sinn, E., Muller, W., Pattengale, P., Tepler, I., Wallace, R. & Leder, P. (1987) Cell 49, 465-475.
16. Muller, W. J., Sinn, E., Pattengale, P. K., Wallace, R. & Leder, P. (1988) Cell 54, 105-115.
17. Ludwig, T., Fisher, P., Murty, V. & Efstratiadis, A. (2001) Oncogene 20, 3937-3948.
18. Iso, T., Kedes, L. & Hamamori, Y. (2003) J. Cell. Physiol. 194, 237-255.
19. de Alboran, I. M., O'Hagan, R. C., Gartner, F., Malynn, B., Davidson, L, Rickert, R., Rajewsky, K., DePinho, R. A. & Alt, F. W. (2001) Immunity 14, 45-55.
20. Robinson, G. W., McKnight, R. A., Smith, G. H. & Hennighausen, L. (1995) Development (Cambridge, U.K.) 121, 2079-2090.
21. Ahmed, F., Wyckoff, J., Lin, E. Y., Wang, W., Wang, Y., Hennighausen, L., Miyazaki, J., Jones, J., Pollard, J. W., Condeelis, J. S. & Segall, J. E. (2002) Cancer Res. 62, 7166-7169.
22. Xu, X., Wagner, K. U., Larson, D., Weaver, Z., Li, C., Ried, T., Hennighausen, L., Wynshaw-Boris, A. & Deng, C. X. (1999) Nat. Genet. 22, 37-43.
23. Walton, K. D., Wagner, K. U., Rucker, E. B., III, Shillingford, J. M., Miyoshi, K. & Hennighausen, L. (2001) Mech. Dev. 109, 281-293.
24. Asselin, C., Nepveu, A. & Marcu, K. B. (1989) Oncogene 4, 549-558.
25. Kovall, R. A. & Hendrickson, W. A. (2004) EMBO J. 23, 3441-3451.
26. Waltzer, L., Bourillot, P. Y., Sergeant, A. & Manet, E. (1995) Nucleic Acids Res. 23, 4939-4945.
27. Nakae, K., Nakajirna, K., Inazawa, J., Kitaoka, T. & Hirano, T. (1995) J. Biol. Chem. 270, 23795-23800.
28. Rao, P. & Kadesch, T. (2003) Mol. Cell. Biol. 23, 6694-6701.
29. Satoh, Y., Matsumura, I., Tanaka, H., Ezoe, S., Sugahara, H., Mizuki, M., Shibayama, H., Ishiko, E., Ishiko, J., Nakajima, K. & Kanakura, Y. (2004) J. Biol. Chem. 279, 24986-24993.
30. Smith, G. H., Gallahan, D., Diella, F., Jhappan, C, Merlino, G. & Callahan, R. (1995) Cell Growth Differ. 6, 563-577.
31. Dietrich, P., Dragatsis, I., Xuan, S., Zeitlin, S. & Efstratiadis, A. (2000) Mamm. Genome 11, 196-205.
32. Parekh, B. S. & Maniatis, T. (1999) Mol. Cell 3, 125-129.
33. Politi, K., Szabolcs, M., Fisher, P., Kljuic, A., Ludwig, T. & Efstratiadis, A. (2004) Am. J. Pathol. 164, 325-336.