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Volumn 22, Issue 10-12, 2007, Pages 1129-1147

Bone morphogenetic proteins and their receptor signaling in prostate cancer

Author keywords

Bone metastasis; Bone morphogenetic protein; Cancer biology; Prostate cancer

Indexed keywords

AURORA A KINASE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 10; BONE MORPHOGENETIC PROTEIN 12; BONE MORPHOGENETIC PROTEIN 15; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 5; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN 8A; BONE MORPHOGENETIC PROTEIN 8B; BONE MORPHOGENETIC PROTEIN 9; BONE MORPHOGENETIC PROTEIN RECEPTOR; CYTOKINE; GROWTH DIFFERENTIATION FACTOR 1; GROWTH DIFFERENTIATION FACTOR 10; GROWTH DIFFERENTIATION FACTOR 11; GROWTH DIFFERENTIATION FACTOR 15; GROWTH DIFFERENTIATION FACTOR 3; GROWTH DIFFERENTIATION FACTOR 4; GROWTH DIFFERENTIATION FACTOR 5; GROWTH DIFFERENTIATION FACTOR 6; GROWTH DIFFERENTIATION FACTOR 9; GROWTH FACTOR; MYOSTATIN; NOGGIN; OSTEOGENIC PROTEIN 1; OSTEOGENIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; TUMOR MARKER;

EID: 34547580553     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (86)

References (203)
  • 1
    • 0034990212 scopus 로고    scopus 로고
    • Effect of bone morphogenetic protein-6 on haemopoietic stem cells and cytokine production in normal human bone marrow stroma
    • Ahmed N., Sammons J., Carson R.J., Khokher M.A. and Hassan H.T. (2001). Effect of bone morphogenetic protein-6 on haemopoietic stem cells and cytokine production in normal human bone marrow stroma. Cell Biol. Int. 25, 429-435.
    • (2001) Cell Biol. Int , vol.25 , pp. 429-435
    • Ahmed, N.1    Sammons, J.2    Carson, R.J.3    Khokher, M.A.4    Hassan, H.T.5
  • 2
    • 33747762981 scopus 로고    scopus 로고
    • Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis
    • 7, 831-837
    • Andersson O., Reissmann E. and Ibanez C.F. (2006). Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis. EMBO Rep. 7, 831-837.
    • (2006) EMBO Rep
    • Andersson, O.1    Reissmann, E.2    Ibanez, C.F.3
  • 3
    • 0035012642 scopus 로고    scopus 로고
    • Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction
    • Aoki H., Fujii M., Imamura T., Yagi K., Takehara K., Kato M. and Miyazono K. (2001). Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction. J. Cell Sci. 114, 1483-1489.
    • (2001) J. Cell Sci , vol.114 , pp. 1483-1489
    • Aoki, H.1    Fujii, M.2    Imamura, T.3    Yagi, K.4    Takehara, K.5    Kato, M.6    Miyazono, K.7
  • 5
    • 0040968520 scopus 로고    scopus 로고
    • A new Smurf in the village
    • Arora K. and Warrior R. (2001). A new Smurf in the village. Dev. Cell 1, 441-442.
    • (2001) Dev. Cell , vol.1 , pp. 441-442
    • Arora, K.1    Warrior, R.2
  • 7
    • 0031723689 scopus 로고    scopus 로고
    • Bone morphogenetic protein 6 in skeletal metastases from prostate cancer and other common human malignancies
    • Autzen P., Robson C.N., Bjartell A., Malcolm A.J., Johnson M.I., Neal D.E. and Hamdy F.C. (1998). Bone morphogenetic protein 6 in skeletal metastases from prostate cancer and other common human malignancies. Br. J. Cancer 78, 1219-1223.
    • (1998) Br. J. Cancer , vol.78 , pp. 1219-1223
    • Autzen, P.1    Robson, C.N.2    Bjartell, A.3    Malcolm, A.J.4    Johnson, M.I.5    Neal, D.E.6    Hamdy, F.C.7
  • 9
    • 0036399170 scopus 로고    scopus 로고
    • Extracellular regulation of BMP signaling in vertebrates: A cocktail of modulators
    • Balemans W. and Van Hul W. (2002). Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. Dev. Biol. 250, 231-250.
    • (2002) Dev. Biol , vol.250 , pp. 231-250
    • Balemans, W.1    Van Hul, W.2
  • 10
    • 0029422455 scopus 로고
    • Bone morphogenetic protein-6 expression in normal and malignant prostate
    • Barnes J., Anthony C.T., Wall N. and Steiner M.S. (1995). Bone morphogenetic protein-6 expression in normal and malignant prostate. World J. Urol. 13, 337-343.
    • (1995) World J. Urol , vol.13 , pp. 337-343
    • Barnes, J.1    Anthony, C.T.2    Wall, N.3    Steiner, M.S.4
  • 11
    • 0035789468 scopus 로고    scopus 로고
    • Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons
    • Beck H.N., Drahushuk K., Jacoby D.B., Higgins D. and Lein P.J. (2001). Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons. BMC Neurosci. 2, 12.
    • (2001) BMC Neurosci , vol.2 , pp. 12
    • Beck, H.N.1    Drahushuk, K.2    Jacoby, D.B.3    Higgins, D.4    Lein, P.J.5
  • 12
    • 0027052350 scopus 로고
    • Expression of bone morphogenetic proteins in human prostatic adenocarcinoma and benign prostatic hyperplasia
    • Bentley H., Hamdy F.C., Hart K.A., Seid J.M., Williams J.L., Johnstone O. and Russell R.G. (1992). Expression of bone morphogenetic proteins in human prostatic adenocarcinoma and benign prostatic hyperplasia. Br. J. Cancer 66, 1159-1163.
    • (1992) Br. J. Cancer , vol.66 , pp. 1159-1163
    • Bentley, H.1    Hamdy, F.C.2    Hart, K.A.3    Seid, J.M.4    Williams, J.L.5    Johnstone, O.6    Russell, R.G.7
  • 14
    • 3242808359 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling in prostate cancer cell lines
    • Brubaker K.D., Corey E., Brown L.G. and Vessella R.L. (2004). Bone morphogenetic protein signaling in prostate cancer cell lines. J. Cell Biochem. 91, 151-160.
    • (2004) J. Cell Biochem , vol.91 , pp. 151-160
    • Brubaker, K.D.1    Corey, E.2    Brown, L.G.3    Vessella, R.L.4
  • 17
    • 0038242149 scopus 로고    scopus 로고
    • A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons
    • Butler S.J. and Dodd J. (2003). A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons. Neuron 38, 389-401.
    • (2003) Neuron , vol.38 , pp. 389-401
    • Butler, S.J.1    Dodd, J.2
  • 18
    • 0242668869 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, their antagonists, and the skeleton
    • Canalis E., Economides A.N. and Gazzerro E. (2003). Bone morphogenetic proteins, their antagonists, and the skeleton. Endocr. Rev. 24, 218-235.
    • (2003) Endocr. Rev , vol.24 , pp. 218-235
    • Canalis, E.1    Economides, A.N.2    Gazzerro, E.3
  • 20
    • 0025672641 scopus 로고
    • Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone
    • Celeste A.J., Iannazzi J.A., Taylor R.C., Hewick R.M., Rosen V., Wang E.A. and Wozney J.M. (1990). Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone. Proc. Natl. Acad. Sci. USA 87, 9843-9847.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9843-9847
    • Celeste, A.J.1    Iannazzi, J.A.2    Taylor, R.C.3    Hewick, R.M.4    Rosen, V.5    Wang, E.A.6    Wozney, J.M.7
  • 21
    • 0000304260 scopus 로고
    • Bone morphogenetic protein-9, a new member of the TGF-beta superfamily
    • Celeste A.J., Song J.J., Cox K., Rosen V. and Wozney J.M. (1994). Bone morphogenetic protein-9, a new member of the TGF-beta superfamily. J. Bone Min. Res. Suppl 1, S136.
    • (1994) J. Bone Min. Res , Issue.SUPPL. 1
    • Celeste, A.J.1    Song, J.J.2    Cox, K.3    Rosen, V.4    Wozney, J.M.5
  • 22
    • 0032856523 scopus 로고    scopus 로고
    • Xenopus GDF6, a new antagonist of noggin and a partner of BMPs
    • Chang C. and Hemmati-Brivanlou A. (1999). Xenopus GDF6, a new antagonist of noggin and a partner of BMPs. Development 126, 3347-3357.
    • (1999) Development , vol.126 , pp. 3347-3357
    • Chang, C.1    Hemmati-Brivanlou, A.2
  • 24
    • 0032504194 scopus 로고    scopus 로고
    • Isolation and characterization of PAGE-1 and GAGE-7. New genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens
    • Chen M.E., Lin S.H., Chung L.W. and Sikes R.A. (1998). Isolation and characterization of PAGE-1 and GAGE-7. New genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens. J. Biol. Chem. 273, 17618-17625.
    • (1998) J. Biol. Chem , vol.273 , pp. 17618-17625
    • Chen, M.E.1    Lin, S.H.2    Chung, L.W.3    Sikes, R.A.4
  • 25
    • 33745388028 scopus 로고    scopus 로고
    • Upregulation of ID protein by growth and differentiation factor 5 (GDF5) through a smad-dependent and MAPK-independent pathway in HUVSMC
    • Chen X., Zankl A., Niroomand F., Liu Z., Katus H.A., Jahn L. and Tiefenbacher C. (2006). Upregulation of ID protein by growth and differentiation factor 5 (GDF5) through a smad-dependent and MAPK-independent pathway in HUVSMC. J. Mol. Cell Cardiol. 41, 26-33.
    • (2006) J. Mol. Cell Cardiol , vol.41 , pp. 26-33
    • Chen, X.1    Zankl, A.2    Niroomand, F.3    Liu, Z.4    Katus, H.A.5    Jahn, L.6    Tiefenbacher, C.7
  • 26
    • 0033524945 scopus 로고    scopus 로고
    • Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors
    • Chen Y.G. and Massague J. (1999). Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors. J. Biol. Chem. 274, 3672-3677.
    • (1999) J. Biol. Chem , vol.274 , pp. 3672-3677
    • Chen, Y.G.1    Massague, J.2
  • 27
    • 0037229696 scopus 로고    scopus 로고
    • EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1
    • Cheng S.K., Olale F., Bennett J.T., Brivanlou A.H. and Schier A.F. (2003). EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. Genes Dev. 17, 31-36.
    • (2003) Genes Dev , vol.17 , pp. 31-36
    • Cheng, S.K.1    Olale, F.2    Bennett, J.T.3    Brivanlou, A.H.4    Schier, A.F.5
  • 30
    • 0033579799 scopus 로고    scopus 로고
    • Expression of bone morphogenetic protein 6 in normal mammary tissue and breast cancer cell lines and its regulation by epidermal growth factor
    • Clement J.H., Sanger J. and Hoffken K. (1999). Expression of bone morphogenetic protein 6 in normal mammary tissue and breast cancer cell lines and its regulation by epidermal growth factor. Int. J. Cancer 80, 250-256.
    • (1999) Int. J. Cancer , vol.80 , pp. 250-256
    • Clement, J.H.1    Sanger, J.2    Hoffken, K.3
  • 31
    • 0033545215 scopus 로고    scopus 로고
    • Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases
    • Constam D.B. and Robertson E.J. (1999). Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases. J. Cell Biol. 144, 139-149.
    • (1999) J. Cell Biol , vol.144 , pp. 139-149
    • Constam, D.B.1    Robertson, E.J.2
  • 32
    • 0032541405 scopus 로고    scopus 로고
    • BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development
    • Cui Y., Jean F., Thomas G. and Christian J.L. (1998). BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development. EMBO J. 17, 4735-4743.
    • (1998) EMBO J , vol.17 , pp. 4735-4743
    • Cui, Y.1    Jean, F.2    Thomas, G.3    Christian, J.L.4
  • 33
    • 0029119066 scopus 로고
    • Growth/differentiation factor-10: A new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3
    • Cunningham N.S., Jenkins N.A., Gilbert D.J., Copeland N.G., Reddi A.H. and Lee S.J. (1995). Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3. Growth Factors 12, 99-109.
    • (1995) Growth Factors , vol.12 , pp. 99-109
    • Cunningham, N.S.1    Jenkins, N.A.2    Gilbert, D.J.3    Copeland, N.G.4    Reddi, A.H.5    Lee, S.J.6
  • 34
    • 24944480253 scopus 로고    scopus 로고
    • Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism
    • Dai J., Keller J., Zhang J., Lu Y., Yao Z. and Keller E.T. (2005). Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res. 65, 8274-8285.
    • (2005) Cancer Res , vol.65 , pp. 8274-8285
    • Dai, J.1    Keller, J.2    Zhang, J.3    Lu, Y.4    Yao, Z.5    Keller, E.T.6
  • 35
    • 10744225879 scopus 로고    scopus 로고
    • Vascular endothelial growth factor contributes to the prostate cancer-induced osteoblast differentiation mediated by bone morphogenetic protein
    • Dai J., Kitagawa Y., Zhang J., Yao Z., Mizokami A., Cheng S., Nor J., McCauley L.K., Taichman R.S. and Keller E.T. (2004). Vascular endothelial growth factor contributes to the prostate cancer-induced osteoblast differentiation mediated by bone morphogenetic protein. Cancer Res. 64, 994-999.
    • (2004) Cancer Res , vol.64 , pp. 994-999
    • Dai, J.1    Kitagawa, Y.2    Zhang, J.3    Yao, Z.4    Mizokami, A.5    Cheng, S.6    Nor, J.7    McCauley, L.K.8    Taichman, R.S.9    Keller, E.T.10
  • 36
    • 0032963512 scopus 로고    scopus 로고
    • Differential patterning of ventral midline cells by axial mesoderm is regulated by BMP7 and chordin
    • Dale K., Sattar N., Heemskerk J., Clarke J.D., Placzek M. and Dodd J. (1999). Differential patterning of ventral midline cells by axial mesoderm is regulated by BMP7 and chordin. Development 126, 397-408.
    • (1999) Development , vol.126 , pp. 397-408
    • Dale, K.1    Sattar, N.2    Heemskerk, J.3    Clarke, J.D.4    Placzek, M.5    Dodd, J.6
  • 38
    • 0033015205 scopus 로고    scopus 로고
    • Isolation of zebrafish gdf7 and comparative genetic mapping of genes belonging to the growth/differentiation tactor 5, 6, 7 subgroup of the TGF-beta superfamily
    • Davidson A.J., Postlethwait J.H., Yan Y.L., Beier D.R., van Doren C., Foernzler D., Celeste A.J., Crosier K.E. and Crosier P.S. (1999). Isolation of zebrafish gdf7 and comparative genetic mapping of genes belonging to the growth/differentiation tactor 5, 6, 7 subgroup of the TGF-beta superfamily. Genome Res. 9, 121-129.
    • (1999) Genome Res , vol.9 , pp. 121-129
    • Davidson, A.J.1    Postlethwait, J.H.2    Yan, Y.L.3    Beier, D.R.4    van Doren, C.5    Foernzler, D.6    Celeste, A.J.7    Crosier, K.E.8    Crosier, P.S.9
  • 39
    • 0034789717 scopus 로고    scopus 로고
    • Bone sialoprotein, bone morphogenetic protein 6 and thymidine phosphorylase expression in localized human prostatic adenocarcinoma as predictors of clinical outcome: A clinicopathological and immunohistochemical study of 43 cases
    • De Pinieux G., Flam T., Zerbib M., Taupin P., Bellahcene A., Waltregny D., Vieillefond A. and Poupon M.F. (2001). Bone sialoprotein, bone morphogenetic protein 6 and thymidine phosphorylase expression in localized human prostatic adenocarcinoma as predictors of clinical outcome: a clinicopathological and immunohistochemical study of 43 cases. J. Urol. 166, 1924-1930.
    • (2001) J. Urol , vol.166 , pp. 1924-1930
    • De Pinieux, G.1    Flam, T.2    Zerbib, M.3    Taupin, P.4    Bellahcene, A.5    Waltregny, D.6    Vieillefond, A.7    Poupon, M.F.8
  • 41
    • 0028800047 scopus 로고
    • Biochemical markers of bone turnover in patients with metastatic bone disease
    • Demers L.M., Costa L., Chinchilli V.M., Gaydos L., Curley E. and Lipton A. (1995). Biochemical markers of bone turnover in patients with metastatic bone disease. Clin. Chem. 41, 1489-1494.
    • (1995) Clin. Chem , vol.41 , pp. 1489-1494
    • Demers, L.M.1    Costa, L.2    Chinchilli, V.M.3    Gaydos, L.4    Curley, E.5    Lipton, A.6
  • 42
    • 0142250328 scopus 로고    scopus 로고
    • Biochemical markers and skeletal metastases
    • Demers L.M., Costa L. and Lipton A. (2003). Biochemical markers and skeletal metastases. Clin. Orthop. Relat. Res. Suppl, 138-147.
    • (2003) Clin. Orthop. Relat. Res , Issue.SUPPL. , pp. 138-147
    • Demers, L.M.1    Costa, L.2    Lipton, A.3
  • 43
    • 0035167441 scopus 로고    scopus 로고
    • Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor beta antagonists
    • Dionne M.S., Skarnes W.C. and Harland R.M. (2001). Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor beta antagonists. Mol. Cell Biol. 21, 636-643.
    • (2001) Mol. Cell Biol , vol.21 , pp. 636-643
    • Dionne, M.S.1    Skarnes, W.C.2    Harland, R.M.3
  • 44
    • 0031786855 scopus 로고    scopus 로고
    • The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes
    • Dube J.L., Wang P., Elvin J., Lyons K.M., Celeste A.J. and Matzuk M.M. (1998). The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes. Mol. Endocrinol. 12, 1809-1817.
    • (1998) Mol. Endocrinol , vol.12 , pp. 1809-1817
    • Dube, J.L.1    Wang, P.2    Elvin, J.3    Lyons, K.M.4    Celeste, A.J.5    Matzuk, M.M.6
  • 49
    • 0033120212 scopus 로고    scopus 로고
    • A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos
    • Gamer L.W., Wolfman N.M., Celeste A.J., Hattersley G., Hewick R. and Rosen V. (1999). A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos. Dev. Biol. 208, 222-232.
    • (1999) Dev. Biol , vol.208 , pp. 222-232
    • Gamer, L.W.1    Wolfman, N.M.2    Celeste, A.J.3    Hattersley, G.4    Hewick, R.5    Rosen, V.6
  • 50
    • 0033962103 scopus 로고    scopus 로고
    • Markers of bone turnover for the management of patients with bone metastases from prostate cancer
    • Garnero P., Buchs N., Zekri J., Rizzoli R., Coleman R.E. and Delmas P.D. (2000). Markers of bone turnover for the management of patients with bone metastases from prostate cancer. Br. J. Cancer 82, 858-864.
    • (2000) Br. J. Cancer , vol.82 , pp. 858-864
    • Garnero, P.1    Buchs, N.2    Zekri, J.3    Rizzoli, R.4    Coleman, R.E.5    Delmas, P.D.6
  • 51
    • 0032535785 scopus 로고    scopus 로고
    • Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts
    • Gazzerro E., Gangji V. and Canalis E. (1998). Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts. J. Clin. Invest. 102, 2106-2114.
    • (1998) J. Clin. Invest , vol.102 , pp. 2106-2114
    • Gazzerro, E.1    Gangji, V.2    Canalis, E.3
  • 52
    • 0942298179 scopus 로고    scopus 로고
    • DAN directs endolymphatic sac and duct outgrowth in the avian inner ear
    • Gerlach-Bank L.M., Cleveland A.R. and Barald K.F. (2004). DAN directs endolymphatic sac and duct outgrowth in the avian inner ear. Dev. Dyn. 229, 219-230.
    • (2004) Dev. Dyn , vol.229 , pp. 219-230
    • Gerlach-Bank, L.M.1    Cleveland, A.R.2    Barald, K.F.3
  • 54
    • 0032899751 scopus 로고    scopus 로고
    • Three-finger toxin fold for the extracellular ligand-binding domain of the type II activin receptor serine kinase
    • Greenwald J., Fischer W.H., Vale W.W. and Choe S. (1999). Three-finger toxin fold for the extracellular ligand-binding domain of the type II activin receptor serine kinase. Nat. Struct. Biol. 6, 18-22.
    • (1999) Nat. Struct. Biol , vol.6 , pp. 18-22
    • Greenwald, J.1    Fischer, W.H.2    Vale, W.W.3    Choe, S.4
  • 55
    • 0035141917 scopus 로고    scopus 로고
    • Bambi is coexpressed with Bmp-4 during mouse embryogenesis
    • Grotewold L., Plum M., Dildrop R., Peters T. and Ruther U. (2001). Bambi is coexpressed with Bmp-4 during mouse embryogenesis. Mech. Dev. 100, 327-330.
    • (2001) Mech. Dev , vol.100 , pp. 327-330
    • Grotewold, L.1    Plum, M.2    Dildrop, R.3    Peters, T.4    Ruther, U.5
  • 59
    • 0030845818 scopus 로고    scopus 로고
    • Immunolocalization and messenger RNA expression of bone morphogenetic protein-6 in human benign and malignant prostatic tissue
    • Hamdy F.C., Autzen P., Robinson M.C., Horne C.H., Neal D.E. and Robson C.N. (1997). Immunolocalization and messenger RNA expression of bone morphogenetic protein-6 in human benign and malignant prostatic tissue. Cancer Res. 57, 4427-4431.
    • (1997) Cancer Res , vol.57 , pp. 4427-4431
    • Hamdy, F.C.1    Autzen, P.2    Robinson, M.C.3    Horne, C.H.4    Neal, D.E.5    Robson, C.N.6
  • 61
    • 0028349054 scopus 로고
    • Expression of bone morphogenetic protein messenger RNAs by normal rat and human prostate and prostate cancer cells
    • Harris S.E., Harris M.A., Mahy P., Wozney J., Feng J.Q. and Mundy G.R. (1994). Expression of bone morphogenetic protein messenger RNAs by normal rat and human prostate and prostate cancer cells. Prostate 24, 204-211.
    • (1994) Prostate , vol.24 , pp. 204-211
    • Harris, S.E.1    Harris, M.A.2    Mahy, P.3    Wozney, J.4    Feng, J.Q.5    Mundy, G.R.6
  • 62
    • 17244374844 scopus 로고    scopus 로고
    • Posttranslational processing of mouse and human BMP-15: Potential implication in the determination of ovulation quota
    • Hashimoto O., Moore R.K. and Shimasaki S. (2005). Posttranslational processing of mouse and human BMP-15: potential implication in the determination of ovulation quota. Proc Natl. Acad. Sci. USA 102, 5426-5431.
    • (2005) Proc Natl. Acad. Sci. USA , vol.102 , pp. 5426-5431
    • Hashimoto, O.1    Moore, R.K.2    Shimasaki, S.3
  • 63
    • 8544275320 scopus 로고    scopus 로고
    • Bone morphogenetic protein (BMP)-6 signaling and BMP antagonist noggin in prostate cancer
    • Haudenschild D.R., Palmer S.M., Moseley T.A., You Z. and Reddi A.H. (2004). Bone morphogenetic protein (BMP)-6 signaling and BMP antagonist noggin in prostate cancer. Cancer Res. 64, 8276-8284.
    • (2004) Cancer Res , vol.64 , pp. 8276-8284
    • Haudenschild, D.R.1    Palmer, S.M.2    Moseley, T.A.3    You, Z.4    Reddi, A.H.5
  • 65
    • 0035863916 scopus 로고    scopus 로고
    • Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells
    • Hjertner O., Hjorth-Hansen H., Borset M., Seidel C., Waage A. and Sundan A. (2001). Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells. Blood 97, 516-522.
    • (2001) Blood , vol.97 , pp. 516-522
    • Hjertner, O.1    Hjorth-Hansen, H.2    Borset, M.3    Seidel, C.4    Waage, A.5    Sundan, A.6
  • 67
    • 0028043978 scopus 로고
    • Cloning and expression of recombinant human growth/differentiation factor 5
    • Hotten G., Neidhardt H., Jacobowsky B. and Pohl J. (1994). Cloning and expression of recombinant human growth/differentiation factor 5. Biochem. Biophys. Res. Commun. 204, 646-652.
    • (1994) Biochem. Biophys. Res. Commun , vol.204 , pp. 646-652
    • Hotten, G.1    Neidhardt, H.2    Jacobowsky, B.3    Pohl, J.4
  • 68
    • 0027287757 scopus 로고
    • Autocrine regulation of prostate-specific antigen gene expression in a human prostatic cancer (LNCaP) subline
    • Hsieh J.T., Wu H.C., Gleave M.E., von Eschenbach A.C. and Chung L.W. (1993). Autocrine regulation of prostate-specific antigen gene expression in a human prostatic cancer (LNCaP) subline. Cancer Res. 53, 2852-2857.
    • (1993) Cancer Res , vol.53 , pp. 2852-2857
    • Hsieh, J.T.1    Wu, H.C.2    Gleave, M.E.3    von Eschenbach, A.C.4    Chung, L.W.5
  • 69
    • 0032039482 scopus 로고    scopus 로고
    • The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities
    • Hsu D.R., Economides A.N., Wang X., Eimon P.M. and Harland R.M. (1998). The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol. Cell 1, 673-683.
    • (1998) Mol. Cell , vol.1 , pp. 673-683
    • Hsu, D.R.1    Economides, A.N.2    Wang, X.3    Eimon, P.M.4    Harland, R.M.5
  • 70
    • 0030716244 scopus 로고    scopus 로고
    • Growth regulation of human prostate cancer cells by bone morphogenetic protein-2
    • Ide H., Yoshida T., Matsumoto N., Aoki K., Osada Y., Sugimura T. and Terada M. (1997). Growth regulation of human prostate cancer cells by bone morphogenetic protein-2. Cancer Res. 57, 5022-5027.
    • (1997) Cancer Res , vol.57 , pp. 5022-5027
    • Ide, H.1    Yoshida, T.2    Matsumoto, N.3    Aoki, K.4    Osada, Y.5    Sugimura, T.6    Terada, M.7
  • 71
    • 0032482928 scopus 로고    scopus 로고
    • Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo
    • Iemura S., Yamamoto T.S., Takagi C., Uchiyama H., Natsume T., Shimasaki S., Sugino H. and Ueno N. (1998). Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo. Proc. Natl. Acad. Sci. USA 95, 9337-9342.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9337-9342
    • Iemura, S.1    Yamamoto, T.S.2    Takagi, C.3    Uchiyama, H.4    Natsume, T.5    Shimasaki, S.6    Sugino, H.7    Ueno, N.8
  • 73
    • 0033531948 scopus 로고    scopus 로고
    • Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells
    • Ishisaki A., Yamato K., Hashimoto S., Nakao A., Tamaki K., Nonaka K., ten Dijke P., Sugino H. and Nishihara T. (1999). Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells. J. Biol. Chem. 274, 13637-13642.
    • (1999) J. Biol. Chem , vol.274 , pp. 13637-13642
    • Ishisaki, A.1    Yamato, K.2    Hashimoto, S.3    Nakao, A.4    Tamaki, K.5    Nonaka, K.6    ten Dijke, P.7    Sugino, H.8    Nishihara, T.9
  • 76
    • 0035422199 scopus 로고    scopus 로고
    • Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads
    • Itoh F., Asao H., Sugamura K., Heldin C.H., ten Dijke P. and Itoh S. (2001). Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads. EMBO J. 20, 4132-4142.
    • (2001) EMBO J , vol.20 , pp. 4132-4142
    • Itoh, F.1    Asao, H.2    Sugamura, K.3    Heldin, C.H.4    ten Dijke, P.5    Itoh, S.6
  • 77
    • 0035895912 scopus 로고    scopus 로고
    • The orphan receptor serine/threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line
    • Jornvall H., Blokzijl A., ten Dijke P. and Ibanez C.F. (2001). The orphan receptor serine/threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line. J. Biol. Chem. 276, 5140-5146.
    • (2001) J. Biol. Chem , vol.276 , pp. 5140-5146
    • Jornvall, H.1    Blokzijl, A.2    ten Dijke, P.3    Ibanez, C.F.4
  • 78
    • 2442443317 scopus 로고    scopus 로고
    • Down-regulation of macrophage inhibitory cytokine-1/prostate derived factor in benign prostatic hyperplasia
    • Kakehi Y., Segawa T., Wu X.X., Kulkarni P., Dhir R. and Getzenberg R.H. (2004). Down-regulation of macrophage inhibitory cytokine-1/prostate derived factor in benign prostatic hyperplasia. Prostate 59, 351-356.
    • (2004) Prostate , vol.59 , pp. 351-356
    • Kakehi, Y.1    Segawa, T.2    Wu, X.X.3    Kulkarni, P.4    Dhir, R.5    Getzenberg, R.H.6
  • 79
    • 33645226966 scopus 로고    scopus 로고
    • Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts
    • Kaneki H., Guo R., Chen D., Yao Z., Schwarz E.M., Zhang Y.E., Boyce B.F. and Xing L. (2006). Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts. J. Biol. Chem. 281, 4326-4333.
    • (2006) J. Biol. Chem , vol.281 , pp. 4326-4333
    • Kaneki, H.1    Guo, R.2    Chen, D.3    Yao, Z.4    Schwarz, E.M.5    Zhang, Y.E.6    Boyce, B.F.7    Xing, L.8
  • 80
    • 0342657717 scopus 로고    scopus 로고
    • Expression of bone marphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues
    • Kim I.Y., Lee D.H., Ahn H.J., Takunaga H., Song W., Devereaux L.M., Jin D., Sampath T.K. and Morton R.A. (2000). Expression of bone marphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues. Cancer Res. 60, 2840-2844.
    • (2000) Cancer Res , vol.60 , pp. 2840-2844
    • Kim, I.Y.1    Lee, D.H.2    Ahn, H.J.3    Takunaga, H.4    Song, W.5    Devereaux, L.M.6    Jin, D.7    Sampath, T.K.8    Morton, R.A.9
  • 81
    • 7044221776 scopus 로고    scopus 로고
    • Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells
    • Kim I.Y., Lee D.H., Lee D.K., Ahn H.J., Kim M.M., Kim S.J. and Morton R.A. (2004). Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells. Oncogene 23, 7651-7659.
    • (2004) Oncogene , vol.23 , pp. 7651-7659
    • Kim, I.Y.1    Lee, D.H.2    Lee, D.K.3    Ahn, H.J.4    Kim, M.M.5    Kim, S.J.6    Morton, R.A.7
  • 82
    • 0034625342 scopus 로고    scopus 로고
    • BMP2-induced apoptosis is mediated by activation at the TAK1-p38 kinase pathway that is negatively regulated by Smad6
    • Kimura N., Matsuo R., Shibuya H., Nakashima K. and Taga T. (2000). BMP2-induced apoptosis is mediated by activation at the TAK1-p38 kinase pathway that is negatively regulated by Smad6. J. Biol. Chem. 275, 17647-17652.
    • (2000) J. Biol. Chem , vol.275 , pp. 17647-17652
    • Kimura, N.1    Matsuo, R.2    Shibuya, H.3    Nakashima, K.4    Taga, T.5
  • 83
    • 0034043106 scopus 로고    scopus 로고
    • Crystal structure of the BMP-2-BRIA ectodomain complex
    • Kirsch T., Sebald W. and Dreyer M.K. (2000). Crystal structure of the BMP-2-BRIA ectodomain complex. Nat. Struct. Biol. 7, 492-496.
    • (2000) Nat. Struct. Biol , vol.7 , pp. 492-496
    • Kirsch, T.1    Sebald, W.2    Dreyer, M.K.3
  • 84
    • 22744449315 scopus 로고    scopus 로고
    • Desmoid tumor with ossification in chest wall: Possible involvement of BAMBI promoter hypermethylation in metaplastic bone formation
    • Kitazawa S., Kitazawa R., Obayashi C. and Yamamoto T. (2005). Desmoid tumor with ossification in chest wall: possible involvement of BAMBI promoter hypermethylation in metaplastic bone formation. J. Bone Miner. Res. 20, 1472-1477.
    • (2005) J. Bone Miner. Res , vol.20 , pp. 1472-1477
    • Kitazawa, S.1    Kitazawa, R.2    Obayashi, C.3    Yamamoto, T.4
  • 85
    • 0034659787 scopus 로고    scopus 로고
    • Hormone therapy for patients with prostate carcinoma
    • Klotz L. (2000). Hormone therapy for patients with prostate carcinoma. Cancer 88, 3009-3014.
    • (2000) Cancer , vol.88 , pp. 3009-3014
    • Klotz, L.1
  • 87
    • 0142091251 scopus 로고    scopus 로고
    • Gene array analysis of bone morphogenetic protein type I receptor-induced osteoblast differentiation
    • Korchynskyi O., Dechering K.J., Sijbers A.M., Olijve W. and ten Dijke P. (2003). Gene array analysis of bone morphogenetic protein type I receptor-induced osteoblast differentiation. J. Bone Miner. Res. 18, 1177-1185.
    • (2003) J. Bone Miner. Res , vol.18 , pp. 1177-1185
    • Korchynskyi, O.1    Dechering, K.J.2    Sijbers, A.M.3    Olijve, W.4    ten Dijke, P.5
  • 88
    • 2942536704 scopus 로고    scopus 로고
    • Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein
    • Kowanetz M., Valcourt U., Bergstrom R., Heldin C.H. and Moustakas A. (2004). Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein. Mol. Cell Biol. 24, 4241-4254.
    • (2004) Mol. Cell Biol , vol.24 , pp. 4241-4254
    • Kowanetz, M.1    Valcourt, U.2    Bergstrom, R.3    Heldin, C.H.4    Moustakas, A.5
  • 89
    • 27144460581 scopus 로고    scopus 로고
    • Interaction between the bone morphogenetic proteins and Ras/MAP-kinase signalling pathways in lung cancer
    • Kraunz K.S., Nelson H.H., Liu M., Wiencke J.K. and Kelsey K.T. (2005). Interaction between the bone morphogenetic proteins and Ras/MAP-kinase signalling pathways in lung cancer. Br. J. Cancer 93, 949-952.
    • (2005) Br. J. Cancer , vol.93 , pp. 949-952
    • Kraunz, K.S.1    Nelson, H.H.2    Liu, M.3    Wiencke, J.K.4    Kelsey, K.T.5
  • 90
    • 0031911356 scopus 로고    scopus 로고
    • SMADs: Mediators and regulators of TGF-beta signaling
    • Kretzschmar M. and Massague J. (1998). SMADs: mediators and regulators of TGF-beta signaling. Curr. Opin. Genet. Dev. 8, 103-111.
    • (1998) Curr. Opin. Genet. Dev , vol.8 , pp. 103-111
    • Kretzschmar, M.1    Massague, J.2
  • 91
    • 15944370597 scopus 로고    scopus 로고
    • NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor
    • Kuratomi G., Komuro A., Goto K., Shinozaki M., Miyazawa K., Miyazono K. and Imamura T. (2005). NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor. Biochem. J. 386, 461-470.
    • (2005) Biochem. J , vol.386 , pp. 461-470
    • Kuratomi, G.1    Komuro, A.2    Goto, K.3    Shinozaki, M.4    Miyazawa, K.5    Miyazono, K.6    Imamura, T.7
  • 92
    • 0038267120 scopus 로고    scopus 로고
    • Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity
    • Kusu N., Laurikkala J., Imanishi M., Usui H., Konishi M., Miyake A., Thesleff I. and Itoh N. (2003). Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity. J. Biol. Chem. 278, 24113-24117.
    • (2003) J. Biol. Chem , vol.278 , pp. 24113-24117
    • Kusu, N.1    Laurikkala, J.2    Imanishi, M.3    Usui, H.4    Konishi, M.5    Miyake, A.6    Thesleff, I.7    Itoh, N.8
  • 93
    • 1942437975 scopus 로고    scopus 로고
    • Medical castration with LHRH agonists: 25 years later with major benefits achieved on survival in prostate cancer
    • Labrie F. (2004). Medical castration with LHRH agonists: 25 years later with major benefits achieved on survival in prostate cancer. J. Androl. 25, 305-313.
    • (2004) J. Androl , vol.25 , pp. 305-313
    • Labrie, F.1
  • 94
    • 0141814613 scopus 로고    scopus 로고
    • The mature bone morphogenetic protein-2 is aberrantly expressed in non-small cell lung carcinomas and stimulates tumor growth of A549 cells
    • Langenfeld E.M., Calvano S.E., Abou-Nukta F., Lowry S.F., Amenta P. and Langenfeld J. (2003). The mature bone morphogenetic protein-2 is aberrantly expressed in non-small cell lung carcinomas and stimulates tumor growth of A549 cells. Carcinogenesis 24, 1445-1454.
    • (2003) Carcinogenesis , vol.24 , pp. 1445-1454
    • Langenfeld, E.M.1    Calvano, S.E.2    Abou-Nukta, F.3    Lowry, S.F.4    Amenta, P.5    Langenfeld, J.6
  • 95
    • 29944440746 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2-induced transformation involves the activation of mammalian target of rapamycin
    • Langenfeld E.M., Kong Y. and Langenfeld J. (2005). Bone morphogenetic protein-2-induced transformation involves the activation of mammalian target of rapamycin. Mol. Cancer Res. 3, 679-684.
    • (2005) Mol. Cancer Res , vol.3 , pp. 679-684
    • Langenfeld, E.M.1    Kong, Y.2    Langenfeld, J.3
  • 96
    • 0032213969 scopus 로고    scopus 로고
    • Neuronal patterning by BMPs: A requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord
    • Lee K.J., Mendelsohn M. and Jessell T.M. (1998). Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord. Genes Dev. 12, 3394-3407.
    • (1998) Genes Dev , vol.12 , pp. 3394-3407
    • Lee, K.J.1    Mendelsohn, M.2    Jessell, T.M.3
  • 97
    • 0025167701 scopus 로고
    • Identification of a novel member (GDF-1) of the transforming growth factor-beta superfamily
    • Lee S.J. (1990). Identification of a novel member (GDF-1) of the transforming growth factor-beta superfamily. Mol. Endocrinol. 4, 1034-1040.
    • (1990) Mol. Endocrinol , vol.4 , pp. 1034-1040
    • Lee, S.J.1
  • 98
    • 0035979253 scopus 로고    scopus 로고
    • Regulation of myostatin activity and muscle growth
    • Lee S.J. and McPherron A.C. (2001). Regulation of myostatin activity and muscle growth. Proc. Natl. Acad. Sci. USA 98, 9306-9311.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9306-9311
    • Lee, S.J.1    McPherron, A.C.2
  • 99
    • 0036023042 scopus 로고    scopus 로고
    • TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB
    • Lee S.W., Han S.I., Kim H.H. and Lee Z.H. (2002). TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB. J. Biochem. Mol. Biol. 35, 371-376.
    • (2002) J. Biochem. Mol. Biol , vol.35 , pp. 371-376
    • Lee, S.W.1    Han, S.I.2    Kim, H.H.3    Lee, Z.H.4
  • 100
    • 0345831221 scopus 로고    scopus 로고
    • Differences in the cytokine profiles associated with prostate cancer cell induced osteoblastic and osteolytic lesions in bone
    • Lee Y., Schwarz E., Davies M., Jo M., Gates J., Wu J., Zhang X. and Lieberman J.R. (2003). Differences in the cytokine profiles associated with prostate cancer cell induced osteoblastic and osteolytic lesions in bone. J. Orthop. Res. 21, 62-72.
    • (2003) J. Orthop. Res , vol.21 , pp. 62-72
    • Lee, Y.1    Schwarz, E.2    Davies, M.3    Jo, M.4    Gates, J.5    Wu, J.6    Zhang, X.7    Lieberman, J.R.8
  • 102
    • 0029008597 scopus 로고
    • Human type II receptor for bone morphogenic proteins (BMPs): Extension of the two-kinase receptor model to the BMPs
    • Liu F., Ventura F., Doody J. and Massague J. (1995). Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs. Mol. Cell Biol. 15, 3479-3486.
    • (1995) Mol. Cell Biol , vol.15 , pp. 3479-3486
    • Liu, F.1    Ventura, F.2    Doody, J.3    Massague, J.4
  • 103
    • 33646566834 scopus 로고    scopus 로고
    • Developmental pattern of expression of BMP receptors and Smads and activation of Smad1 and Smad5 by BMP9 in mouse basal forebrain
    • Lopez-Coviella I., Mellott T.M., Kovacheva V.P., Berse B., Slack B.E., Zemelko V., Schnitzler A. and Blusztajn J.K. (2006). Developmental pattern of expression of BMP receptors and Smads and activation of Smad1 and Smad5 by BMP9 in mouse basal forebrain. Brain Res. 1088, 49-56.
    • (2006) Brain Res , vol.1088 , pp. 49-56
    • Lopez-Coviella, I.1    Mellott, T.M.2    Kovacheva, V.P.3    Berse, B.4    Slack, B.E.5    Zemelko, V.6    Schnitzler, A.7    Blusztajn, J.K.8
  • 104
    • 0033200361 scopus 로고    scopus 로고
    • The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling
    • Luo K., Stroschein S.L., Wang W., Chen D., Martens E., Zhou S. and Zhou Q. (1999). The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling. Genes Dev. 13, 2196-2206.
    • (1999) Genes Dev , vol.13 , pp. 2196-2206
    • Luo, K.1    Stroschein, S.L.2    Wang, W.3    Chen, D.4    Martens, E.5    Zhou, S.6    Zhou, Q.7
  • 105
    • 4644289915 scopus 로고    scopus 로고
    • The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis
    • Marques S., Borges A.C., Silva A.C., Freitas S., Cordenonsi M. and Belo J.A. (2004). The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis. Genes Dev. 18, 2342-2347.
    • (2004) Genes Dev , vol.18 , pp. 2342-2347
    • Marques, S.1    Borges, A.C.2    Silva, A.C.3    Freitas, S.4    Cordenonsi, M.5    Belo, J.A.6
  • 106
    • 1642402864 scopus 로고    scopus 로고
    • Expression of bone morphogenetic protein-7 (BMP-7) in human prostate
    • Masuda H., Fukabori Y., Nakano K., Shimizu N. and Yamanaka H. (2004). Expression of bone morphogenetic protein-7 (BMP-7) in human prostate. Prostate 59, 101-106.
    • (2004) Prostate , vol.59 , pp. 101-106
    • Masuda, H.1    Fukabori, Y.2    Nakano, K.3    Shimizu, N.4    Yamanaka, H.5
  • 107
    • 0037369118 scopus 로고    scopus 로고
    • Increased expression of bone morphogenetic protein-7 in bone metastatic prostate cancer
    • Masuda H., Fukabori Y., Nakano K., Takezawa Y., T C.S. and Yamanaka H. (2003). Increased expression of bone morphogenetic protein-7 in bone metastatic prostate cancer. Prostate 54, 268-274.
    • (2003) Prostate , vol.54 , pp. 268-274
    • Masuda, H.1    Fukabori, Y.2    Nakano, K.3    Takezawa, Y.T.C.S.4    Yamanaka, H.5
  • 108
    • 33745272290 scopus 로고    scopus 로고
    • Genomic analyses facilitate identification of receptors and signalling pathways for growth differentiation factor 9 and related orphan bone morphogenetic protein/ growth differentiation factor ligands
    • Mazerbourg S. and Hsueh A.J. (2006). Genomic analyses facilitate identification of receptors and signalling pathways for growth differentiation factor 9 and related orphan bone morphogenetic protein/ growth differentiation factor ligands. Hum. Reprod. Update 12, 373-383.
    • (2006) Hum. Reprod. Update , vol.12 , pp. 373-383
    • Mazerbourg, S.1    Hsueh, A.J.2
  • 109
    • 25444529969 scopus 로고    scopus 로고
    • Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses
    • Mazerbourg S., Sangkuhl K., Luo C. W., Sudo S., Klein C. and Hsueh A. J. (2005). Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses. J. Biol. Chem. 280, 32122-32132.
    • (2005) J. Biol. Chem , vol.280 , pp. 32122-32132
    • Mazerbourg, S.1    Sangkuhl, K.2    Luo, C.W.3    Sudo, S.4    Klein, C.5    Hsueh, A.J.6
  • 110
    • 0027401489 scopus 로고
    • GDF-3 and GDF-9: Two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines
    • McPherron A.C. and Lee S.J. (1993). GDF-3 and GDF-9: two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines. J. Biol. Chem. 268, 3444-3449.
    • (1993) J. Biol. Chem , vol.268 , pp. 3444-3449
    • McPherron, A.C.1    Lee, S.J.2
  • 111
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron A.C., Lawler A.M. and Lee S.J. (1997). Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387, 83-90.
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 112
    • 0033052036 scopus 로고    scopus 로고
    • Regulation of anterior/ posterior patterning of the axial skeleton by growth/differentiation factor 11
    • McPherron A.C., Lawler A.M. and Lee S.J. (1999). Regulation of anterior/ posterior patterning of the axial skeleton by growth/differentiation factor 11. Nat. Genet. 22, 260-264.
    • (1999) Nat. Genet , vol.22 , pp. 260-264
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 113
    • 0033402727 scopus 로고    scopus 로고
    • The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb
    • Merino R., Rodriguez-Leon J., Macias D., Ganan Y., Economides A.N. and Hurle J.M. (1999). The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb. Development 126, 5515-5522.
    • (1999) Development , vol.126 , pp. 5515-5522
    • Merino, R.1    Rodriguez-Leon, J.2    Macias, D.3    Ganan, Y.4    Economides, A.N.5    Hurle, J.M.6
  • 114
    • 11244256523 scopus 로고    scopus 로고
    • BMP signals inhibit proliferation and in vivo tumor growth of androgen-insensitive prostate carcinoma cells
    • Miyazaki H., Watabe T., Kitamura T. and Miyazono K. (2004). BMP signals inhibit proliferation and in vivo tumor growth of androgen-insensitive prostate carcinoma cells. Oncogene 23, 9326-9335.
    • (2004) Oncogene , vol.23 , pp. 9326-9335
    • Miyazaki, H.1    Watabe, T.2    Kitamura, T.3    Miyazono, K.4
  • 115
    • 0037414773 scopus 로고    scopus 로고
    • Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells
    • Moore R.K., Otsuka F. and Shimasaki S. (2003). Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells. J. Biol. Chem. 278, 304-310.
    • (2003) J. Biol. Chem , vol.278 , pp. 304-310
    • Moore, R.K.1    Otsuka, F.2    Shimasaki, S.3
  • 116
    • 0031964376 scopus 로고    scopus 로고
    • Antiangiogenic agent (TNP-470) inhibition of ectopic bone formation induced by bone morphogenetic protein-2
    • Mori S., Yoshikawa H., Hashimoto J., Ueda T., Funai H., Kato M. and Takaoka K. (1998). Antiangiogenic agent (TNP-470) inhibition of ectopic bone formation induced by bone morphogenetic protein-2. Bone 22, 99-105.
    • (1998) Bone , vol.22 , pp. 99-105
    • Mori, S.1    Yoshikawa, H.2    Hashimoto, J.3    Ueda, T.4    Funai, H.5    Kato, M.6    Takaoka, K.7
  • 118
    • 0036682542 scopus 로고    scopus 로고
    • From mono- to oligo-Smads: The heart of the matter in TGF-beta signal transduction
    • Moustakas A. and Heldin C.H. (2002). From mono- to oligo-Smads: the heart of the matter in TGF-beta signal transduction. Genes Dev. 16, 1867-1871.
    • (2002) Genes Dev , vol.16 , pp. 1867-1871
    • Moustakas, A.1    Heldin, C.H.2
  • 119
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • Mundy G.R. (2002). Metastasis to bone: causes, consequences and therapeutic opportunities. Nat. Rev. Cancer 2, 584-593.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 584-593
    • Mundy, G.R.1
  • 120
    • 0038107486 scopus 로고    scopus 로고
    • Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads
    • Murakami G., Watabe T., Takaoka K., Miyazono K. and Imamura T. (2003). Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads. Mol. Biol. Cell 14, 2809-2817.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 2809-2817
    • Murakami, G.1    Watabe, T.2    Takaoka, K.3    Miyazono, K.4    Imamura, T.5
  • 122
    • 0037290578 scopus 로고    scopus 로고
    • Growth/differentiation factor-5 induces growth arrest and apoptosis in mouse B lineage cells with modulation by Smad
    • Nakahara T., Tominaga K., Koseki T., Yamamoto M., Yamato K., Fukuda J. and Nishihara T. (2003). Growth/differentiation factor-5 induces growth arrest and apoptosis in mouse B lineage cells with modulation by Smad. Cell Signal 15, 181-187.
    • (2003) Cell Signal , vol.15 , pp. 181-187
    • Nakahara, T.1    Tominaga, K.2    Koseki, T.3    Yamamoto, M.4    Yamato, K.5    Fukuda, J.6    Nishihara, T.7
  • 123
    • 0034141204 scopus 로고    scopus 로고
    • Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: Roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP)
    • Nakajima Y., Yamagishi T., Hokari S. and Nakamura H. (2000). Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP). Anat. Rec. 258, 119-127.
    • (2000) Anat. Rec , vol.258 , pp. 119-127
    • Nakajima, Y.1    Yamagishi, T.2    Hokari, S.3    Nakamura, H.4
  • 125
    • 0030826702 scopus 로고    scopus 로고
    • A kinase domain-truncated type I receptor blocks bone morphogenetic protein-2-induced signal transduction in C2C12 myoblasts
    • Namiki M., Akiyama S., Katagiri T., Suzuki A., Ueno N., Yamaji N., Rosen V., Wozney J.M. and Suda T. (1997). A kinase domain-truncated type I receptor blocks bone morphogenetic protein-2-induced signal transduction in C2C12 myoblasts. J. Biol. Chem. 272, 22046-22052.
    • (1997) J. Biol. Chem , vol.272 , pp. 22046-22052
    • Namiki, M.1    Akiyama, S.2    Katagiri, T.3    Suzuki, A.4    Ueno, N.5    Yamaji, N.6    Rosen, V.7    Wozney, J.M.8    Suda, T.9
  • 126
    • 0032980052 scopus 로고    scopus 로고
    • Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily
    • Neuhaus H., Rosen V. and Thies R.S. (1999). Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily. Mech. Dev. 80, 181-184.
    • (1999) Mech. Dev , vol.80 , pp. 181-184
    • Neuhaus, H.1    Rosen, V.2    Thies, R.S.3
  • 128
    • 0037085287 scopus 로고    scopus 로고
    • The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways
    • Nohe A., Hassel S., Ehrlich M., Neubauer F., Sebald W., Henis Y.I. and Knaus P. (2002). The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways. J. Biol. Chem. 277, 5330-5338.
    • (2002) J. Biol. Chem , vol.277 , pp. 5330-5338
    • Nohe, A.1    Hassel, S.2    Ehrlich, M.3    Neubauer, F.4    Sebald, W.5    Henis, Y.I.6    Knaus, P.7
  • 129
    • 0346996450 scopus 로고    scopus 로고
    • Signal transduction of bone morphogenetic protein receptors
    • Nohe A., Keating E., Knaus P. and Petersen N.O. (2004). Signal transduction of bone morphogenetic protein receptors. Cell Signal. 16, 291-299.
    • (2004) Cell Signal , vol.16 , pp. 291-299
    • Nohe, A.1    Keating, E.2    Knaus, P.3    Petersen, N.O.4
  • 130
    • 0029153741 scopus 로고
    • Identification of a human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with bone morphogenetic protein type I receptors
    • Nohno T., Ishikawa T., Saito T., Hosokawa K., Noji S., Wolsing D.H. and Rosenbaum J.S. (1995). Identification of a human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with bone morphogenetic protein type I receptors. J. Biol. Chem. 270, 22522-22526.
    • (1995) J. Biol. Chem , vol.270 , pp. 22522-22526
    • Nohno, T.1    Ishikawa, T.2    Saito, T.3    Hosokawa, K.4    Noji, S.5    Wolsing, D.H.6    Rosenbaum, J.S.7
  • 131
    • 0027496995 scopus 로고
    • Bone morphogenetic protein 2 transiently enhances expression of a gene, Id (inhibitor of differentiation), encoding a helix-loop-helix molecule in osteoblast-like cells
    • Ogata T., Wozney J.M., Benezra R. and Noda M. (1993). Bone morphogenetic protein 2 transiently enhances expression of a gene, Id (inhibitor of differentiation), encoding a helix-loop-helix molecule in osteoblast-like cells. Proc. Natl. Acad. Sci. USA 90, 9219-9222.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9219-9222
    • Ogata, T.1    Wozney, J.M.2    Benezra, R.3    Noda, M.4
  • 132
    • 0036830490 scopus 로고    scopus 로고
    • Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
    • Oh S.P., Yeo C.Y., Lee Y., Schrewe H., Whitman M. and Li E. (2002). Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning. Genes Dev. 16, 2749-2754.
    • (2002) Genes Dev , vol.16 , pp. 2749-2754
    • Oh, S.P.1    Yeo, C.Y.2    Lee, Y.3    Schrewe, H.4    Whitman, M.5    Li, E.6
  • 136
    • 0026459795 scopus 로고
    • Osteogenic protein-2. A new member of the transforming growth factor-beta superfamily expressed early in embryogenesis
    • Ozkaynak E., Schnegelsberg P.N., Jin D.F., Clifford G.M., Warren F.D., Drier E.A. and Oppermann H. (1992). Osteogenic protein-2. A new member of the transforming growth factor-beta superfamily expressed early in embryogenesis. J. Biol. Chem. 267, 25220-25227.
    • (1992) J. Biol. Chem , vol.267 , pp. 25220-25227
    • Ozkaynak, E.1    Schnegelsberg, P.N.2    Jin, D.F.3    Clifford, G.M.4    Warren, F.D.5    Drier, E.A.6    Oppermann, H.7
  • 139
    • 0030598867 scopus 로고    scopus 로고
    • Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4
    • Piccolo S., Sasai Y., Lu B. and De Robertis E.M. (1996). Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 86, 589-598.
    • (1996) Cell , vol.86 , pp. 589-598
    • Piccolo, S.1    Sasai, Y.2    Lu, B.3    De Robertis, E.M.4
  • 140
    • 23744516720 scopus 로고    scopus 로고
    • Testing the antagonistic effect of follistatin on BMP family members in ovine granulosa cells
    • Pierre A., Pisselet C., Monget P., Monniaux D. and Fabre S. (2005). Testing the antagonistic effect of follistatin on BMP family members in ovine granulosa cells. Reprod. Nutr. Dev. 45, 419-425.
    • (2005) Reprod. Nutr. Dev , vol.45 , pp. 419-425
    • Pierre, A.1    Pisselet, C.2    Monget, P.3    Monniaux, D.4    Fabre, S.5
  • 141
    • 15544381570 scopus 로고    scopus 로고
    • Self-renewal and cancer of the gut: Two sides of a coin
    • Radtke F. and Clevers H. (2005). Self-renewal and cancer of the gut: two sides of a coin. Science 307, 1904-1909.
    • (2005) Science , vol.307 , pp. 1904-1909
    • Radtke, F.1    Clevers, H.2
  • 142
    • 22344442622 scopus 로고    scopus 로고
    • Expression of bone morphogenetic protein 2 in breast cancer cells inhibits hypoxic cell death
    • Raida M., Clement J.H., Ameri K., Han C., Leek R.D. and Harris A.L. (2005). Expression of bone morphogenetic protein 2 in breast cancer cells inhibits hypoxic cell death. Int. J. Oncol. 26, 1465-1470.
    • (2005) Int. J. Oncol , vol.26 , pp. 1465-1470
    • Raida, M.1    Clement, J.H.2    Ameri, K.3    Han, C.4    Leek, R.D.5    Harris, A.L.6
  • 143
    • 0034193208 scopus 로고    scopus 로고
    • Osteogenic protein-1, a bone morphogenetic protein, induces angiogenesis in the chick chorioallantoic membrane and synergizes with basic fibroblast growth factor and transforming growth factor-beta1
    • Ramoshebi L.N. and Ripamonti U. (2000). Osteogenic protein-1, a bone morphogenetic protein, induces angiogenesis in the chick chorioallantoic membrane and synergizes with basic fibroblast growth factor and transforming growth factor-beta1. Anat. Rec. 259, 97-107.
    • (2000) Anat. Rec , vol.259 , pp. 97-107
    • Ramoshebi, L.N.1    Ripamonti, U.2
  • 144
    • 0029616567 scopus 로고
    • Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development
    • Re'em-Kalma Y., Lamb T. and Frank D. (1995). Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development. Proc. Natl. Acad. Sci. USA 92, 12141-12145.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12141-12145
    • Re'em-Kalma, Y.1    Lamb, T.2    Frank, D.3
  • 145
    • 0141864365 scopus 로고    scopus 로고
    • Myostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesis
    • Rebbapragada A., Benchabane H., Wrana J.L., Celeste A.J. and Attisano L. (2003). Myostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesis. Mol. Cell Biol. 23, 7230-7242.
    • (2003) Mol. Cell Biol , vol.23 , pp. 7230-7242
    • Rebbapragada, A.1    Benchabane, H.2    Wrana, J.L.3    Celeste, A.J.4    Attisano, L.5
  • 146
  • 147
    • 0034235433 scopus 로고    scopus 로고
    • Slug is an essential target of TGFbeta2 signaling in the developing chicken heart
    • Romano L.A. and Runyan R.B. (2000). Slug is an essential target of TGFbeta2 signaling in the developing chicken heart. Dev. Biol. 223, 91-102.
    • (2000) Dev. Biol , vol.223 , pp. 91-102
    • Romano, L.A.1    Runyan, R.B.2
  • 150
    • 12544259720 scopus 로고    scopus 로고
    • Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration
    • Rothhammer T., Poser I., Soncin F., Bataille F., Moser M. and Bosserhoff A.K. (2005). Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration. Cancer Res. 65, 448-456.
    • (2005) Cancer Res , vol.65 , pp. 448-456
    • Rothhammer, T.1    Poser, I.2    Soncin, F.3    Bataille, F.4    Moser, M.5    Bosserhoff, A.K.6
  • 154
    • 0028856777 scopus 로고
    • Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus
    • Sasal Y., Lu B., Steinbelsser H. and De Robertis E.M. (1995). Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 378, 419.
    • (1995) Nature , vol.378 , pp. 419
    • Sasal, Y.1    Lu, B.2    Steinbelsser, H.3    De Robertis, E.M.4
  • 155
    • 14944345010 scopus 로고    scopus 로고
    • Tenascin-W is found in malignant mammary tumors, promotes alpha8 integrin-dependent motility and requires p38MAPK activity for BMP-2 and TNF-alpha induced expression in vitro
    • Scherberich A., Tucker R.P., Degen M., Brown-Luedi M., Andres A.C. and Chiquet-Ehrismann R. (2005). Tenascin-W is found in malignant mammary tumors, promotes alpha8 integrin-dependent motility and requires p38MAPK activity for BMP-2 and TNF-alpha induced expression in vitro. Oncogene 24, 1525-1532.
    • (2005) Oncogene , vol.24 , pp. 1525-1532
    • Scherberich, A.1    Tucker, R.P.2    Degen, M.3    Brown-Luedi, M.4    Andres, A.C.5    Chiquet-Ehrismann, R.6
  • 156
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y. and Massague J. (2003). Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113, 685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 159
    • 0037168586 scopus 로고    scopus 로고
    • Strausberg R.L, Feingold E.A, Grouse L.H, Derge J.G, Klausner R.D, Collins F.S, Wagner L, Shenmen C.M, Schuler G.D, Altschul S.F, Zeeberg B, Buetow K.H, Schaefer C.F, Bhat N.K, Hopkins R.F, Jordan H, Moore T, Max S.I, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer A.A, Rubin G.M, Hong L, Stapleton M, Soares M.B, Bonaldo M.F, Casavant T.L, Scheetz T.E, Brownstein M.J, Usdin T.B, Toshiyuki S, Caminci P, Prange C, Raha S.S, Loquellano N.A, Peters G.J, Abramson R.D, Mullahy S.J, Bosak S.A, McEwan P.J, McKernan K.J, Malek J.A, Gunaratne P.H, Richards S, Wonley K.C, Hale S, Garcia A.M, Gay L.J, Hulyk S.W, Villalon D.K, Muzny D.M, Sodergren E.J, Lu X, Gibbs R.A, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Young A.C, Shevchenko Y, Bouffard G.G, Blakesley R.W, Touchman J.W, Green E.D, Dickson M.C, Rodriguez A.C, Grimwood J, Schmutz J, Myers R.M, Butterfield Y.S, Krzywinski M.I, Skalska
    • Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S., Caminci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., Richards S., Wonley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Young A.C., Shevchenko Y., Bouffard G.G., Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I., Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J. and Marra M.A. (2002). Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. USA 99, 16899-16903.
  • 160
    • 0033595704 scopus 로고    scopus 로고
    • Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
    • Stroschein S.L., Wang W., Zhou S., Zhou Q. and Luo K. (1999). Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein. Science 286, 771-774.
    • (1999) Science , vol.286 , pp. 771-774
    • Stroschein, S.L.1    Wang, W.2    Zhou, S.3    Zhou, Q.4    Luo, K.5
  • 161
    • 2542430192 scopus 로고    scopus 로고
    • Protein related to DAN and cerberus is a bone morphogenetic protein antagonist that participates in ovarian paracrine regulation
    • Sudo S., Avsian-Kretchmer O., Wang L.S. and Hsueh A.J. (2004). Protein related to DAN and cerberus is a bone morphogenetic protein antagonist that participates in ovarian paracrine regulation. J. Biol. Chem. 279, 23134-23141.
    • (2004) J. Biol. Chem , vol.279 , pp. 23134-23141
    • Sudo, S.1    Avsian-Kretchmer, O.2    Wang, L.S.3    Hsueh, A.J.4
  • 164
    • 0035108784 scopus 로고    scopus 로고
    • Epigenetic regulation of human bone morphogenetic protein 6 gene expression in prostate cancer
    • Tamada H., Kitazawa R., Gohji K. and Kitazawa S. (2001). Epigenetic regulation of human bone morphogenetic protein 6 gene expression in prostate cancer. J. Bone Miner. Res. 16, 487-496.
    • (2001) J. Bone Miner. Res , vol.16 , pp. 487-496
    • Tamada, H.1    Kitazawa, R.2    Gohji, K.3    Kitazawa, S.4
  • 166
    • 0031757317 scopus 로고    scopus 로고
    • Androgen-dependent gene expression of bone morphogenetic protein 7 in mouse prostate
    • Thomas R., Anderson W.A., Raman V. and Reddi A.H. (1998). Androgen-dependent gene expression of bone morphogenetic protein 7 in mouse prostate. Prostate 37, 236-245.
    • (1998) Prostate , vol.37 , pp. 236-245
    • Thomas, R.1    Anderson, W.A.2    Raman, V.3    Reddi, A.H.4
  • 167
    • 0035399926 scopus 로고    scopus 로고
    • Placental bone morphogenetic protein (PLAB) gene expression in normal, premalignant and malignant human prostate: Relation to tumor development and progression
    • Thomas R., True L.D., Lange P.H. and Vessella R.L. (2001). Placental bone morphogenetic protein (PLAB) gene expression in normal, premalignant and malignant human prostate: relation to tumor development and progression. Int. J. Cancer 93, 47-52.
    • (2001) Int. J. Cancer , vol.93 , pp. 47-52
    • Thomas, R.1    True, L.D.2    Lange, P.H.3    Vessella, R.L.4
  • 168
    • 23044461884 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 induces hypophosphorylation of Rb protein and repression of E2F in androgen-treated LNCaP human prostate cancer cells
    • Tomari K., Kumagai T., Shimizu T. and Takeda K. (2005). Bone morphogenetic protein-2 induces hypophosphorylation of Rb protein and repression of E2F in androgen-treated LNCaP human prostate cancer cells. Int. J. Mol. Med. 15, 253-258.
    • (2005) Int. J. Mol. Med , vol.15 , pp. 253-258
    • Tomari, K.1    Kumagai, T.2    Shimizu, T.3    Takeda, K.4
  • 169
    • 0034731508 scopus 로고    scopus 로고
    • Identification and characterization of a novel follistatin-like protein as a binding protein for the TGF-beta family
    • Tsuchida K., Arai K.Y., Kuramoto Y., Yamakawa N., Hasegawa Y. and Sugino H. (2000). Identification and characterization of a novel follistatin-like protein as a binding protein for the TGF-beta family. J. Biol. Chem. 275, 40788-40796.
    • (2000) J. Biol. Chem , vol.275 , pp. 40788-40796
    • Tsuchida, K.1    Arai, K.Y.2    Kuramoto, Y.3    Yamakawa, N.4    Hasegawa, Y.5    Sugino, H.6
  • 170
    • 0032865255 scopus 로고    scopus 로고
    • Inactivation of proprotein convertase, PACE4, by alpha1-antitrypsin Portland (alpha1 -PDX), a blocker of proteolytic activation of bone morphogenetic protein during embryogenesis: Evidence that PACE4 is able to form an SDS-stable acyl intermediate with alpha1-PDX
    • Tsuji A., Hashimoto E., Ikoma T., Taniguchi T., Mori K., Nagahama M. and Matsuda Y. (1999). Inactivation of proprotein convertase, PACE4, by alpha1-antitrypsin Portland (alpha1 -PDX), a blocker of proteolytic activation of bone morphogenetic protein during embryogenesis: evidence that PACE4 is able to form an SDS-stable acyl intermediate with alpha1-PDX. J. Biochem. (Tokyo) 126, 591-603.
    • (1999) J. Biochem. (Tokyo) , vol.126 , pp. 591-603
    • Tsuji, A.1    Hashimoto, E.2    Ikoma, T.3    Taniguchi, T.4    Mori, K.5    Nagahama, M.6    Matsuda, Y.7
  • 171
    • 34250019537 scopus 로고
    • Bone: Formation by autoinduction
    • Urist M.R. (1965). Bone: formation by autoinduction. Science 150, 893-899.
    • (1965) Science , vol.150 , pp. 893-899
    • Urist, M.R.1
  • 172
    • 0037293657 scopus 로고    scopus 로고
    • Rapamycin induces Smad activity in prostate cancer cell lines
    • van der Poel H.G., Hanrahan C., Zhong H. and Simons J.W. (2003). Rapamycin induces Smad activity in prostate cancer cell lines. Urol. Res. 30, 380-386.
    • (2003) Urol. Res , vol.30 , pp. 380-386
    • van der Poel, H.G.1    Hanrahan, C.2    Zhong, H.3    Simons, J.W.4
  • 173
    • 0034028329 scopus 로고    scopus 로고
    • Ski and SnoN: Antagonistic proteins of TGFbeta signaling
    • Vignais M.L. (2000). Ski and SnoN: antagonistic proteins of TGFbeta signaling. Bull. Cancer 87, 135-137.
    • (2000) Bull. Cancer , vol.87 , pp. 135-137
    • Vignais, M.L.1
  • 174
    • 0034687731 scopus 로고    scopus 로고
    • Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells
    • Wang W., Mariani F.V., Harland R.M. and Luo K. (2000). Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells. Proc. Natl. Acad. Sci. USA 97, 14394-14399.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14394-14399
    • Wang, W.1    Mariani, F.V.2    Harland, R.M.3    Luo, K.4
  • 175
    • 33646362788 scopus 로고    scopus 로고
    • Frequent epigenetic silencing of the bone morphogenetic protein 2 gene through methylation in gastric carcinomas
    • Wen X.Z., Akiyama Y., Baylin S.B. and Yuasa Y. (2006). Frequent epigenetic silencing of the bone morphogenetic protein 2 gene through methylation in gastric carcinomas. Oncogene 25, 2666-2673.
    • (2006) Oncogene , vol.25 , pp. 2666-2673
    • Wen, X.Z.1    Akiyama, Y.2    Baylin, S.B.3    Yuasa, Y.4
  • 176
    • 27944498719 scopus 로고    scopus 로고
    • The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling
    • Wicks S.J., Haros K., Maillard M., Song L., Cohen R.E., Dijke P.T. and Chantry A. (2005). The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling. Oncogene 24, 8080-8084.
    • (2005) Oncogene , vol.24 , pp. 8080-8084
    • Wicks, S.J.1    Haros, K.2    Maillard, M.3    Song, L.4    Cohen, R.E.5    Dijke, P.T.6    Chantry, A.7
  • 179
    • 0028014395 scopus 로고
    • Two distinct transmembrane serine/threonine kinases from Drosophila melanogaster form an activin receptor complex
    • Wrana J.L., Tran H., Attisano L., Arora K., Childs S.R., Massague J. and O'Connor M.B. (1994). Two distinct transmembrane serine/threonine kinases from Drosophila melanogaster form an activin receptor complex. Mol. Cell. Biol. 14, 944-950.
    • (1994) Mol. Cell. Biol , vol.14 , pp. 944-950
    • Wrana, J.L.1    Tran, H.2    Attisano, L.3    Arora, K.4    Childs, S.R.5    Massague, J.6    O'Connor, M.B.7
  • 180
    • 0028321891 scopus 로고
    • Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: Role of bone stromal cells
    • Wu H.C., Hsieh J.T., Gleave M.E., Brown N.M., Pathak S. and Chung L.W. (1994). Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells. Int. J. Cancer 57, 406-412.
    • (1994) Int. J. Cancer , vol.57 , pp. 406-412
    • Wu, H.C.1    Hsieh, J.T.2    Gleave, M.E.3    Brown, N.M.4    Pathak, S.5    Chung, L.W.6
  • 181
    • 33646076196 scopus 로고    scopus 로고
    • GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation
    • Xu J., Kimball T.R., Lorenz J.N., Brown D.A., Bauskin A.R., Klevitsky R., Hewett T.E., Breit S.N. and Molkentin J.D. (2006). GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circ. Res. 98, 342-350.
    • (2006) Circ. Res , vol.98 , pp. 342-350
    • Xu, J.1    Kimball, T.R.2    Lorenz, J.N.3    Brown, D.A.4    Bauskin, A.R.5    Klevitsky, R.6    Hewett, T.E.7    Breit, S.N.8    Molkentin, J.D.9
  • 183
  • 187
    • 21344467705 scopus 로고    scopus 로고
    • Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells
    • Yang S., Zhong C., Frenkel B., Reddi A.H. and Roy-Burman P. (2005). Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells. Cancer Res. 65, 5769-5777.
    • (2005) Cancer Res , vol.65 , pp. 5769-5777
    • Yang, S.1    Zhong, C.2    Frenkel, B.3    Reddi, A.H.4    Roy-Burman, P.5
  • 188
    • 33646271828 scopus 로고    scopus 로고
    • Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathways
    • Yang S., Lim M., Pham L.K., Kendali S.E., Reddi A.H., Altieri D.C. and Roy-Burman P. (2006). Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathways. Cancer Res. 66, 4285-4290.
    • (2006) Cancer Res , vol.66 , pp. 4285-4290
    • Yang, S.1    Lim, M.2    Pham, L.K.3    Kendali, S.E.4    Reddi, A.H.5    Altieri, D.C.6    Roy-Burman, P.7
  • 189
    • 0033587653 scopus 로고    scopus 로고
    • Osteogenic protein-1 increases gene expression of vascular endothelial growth factor in primary cultures of fetal rat calvaria cells
    • Yeh L.C. and Lee J.C. (1999). Osteogenic protein-1 increases gene expression of vascular endothelial growth factor in primary cultures of fetal rat calvaria cells. Mol. Cell Endocrinol. 153, 113-124.
    • (1999) Mol. Cell Endocrinol , vol.153 , pp. 113-124
    • Yeh, L.C.1    Lee, J.C.2
  • 190
    • 19644378914 scopus 로고    scopus 로고
    • Mechanisms of cancer metastasis to the bone
    • Yin J.J., Pollock C.B. and Kelly K. (2005). Mechanisms of cancer metastasis to the bone. Cell Res. 15, 57-62.
    • (2005) Cell Res , vol.15 , pp. 57-62
    • Yin, J.J.1    Pollock, C.B.2    Kelly, K.3
  • 191
    • 0033520394 scopus 로고    scopus 로고
    • Antagonistic signaling by Caronte, a novel Cerberus-related gene, establishes left-right asymmetric gene expression
    • Yokouchi Y., Vogan K.J., Pearse R.V., 2nd and Tabin C.J. (1999). Antagonistic signaling by Caronte, a novel Cerberus-related gene, establishes left-right asymmetric gene expression. Cell 98, 573-583.
    • (1999) Cell , vol.98 , pp. 573-583
    • Yokouchi, Y.1    Vogan, K.J.2    Pearse 2nd, R.V.3    Tabin, C.J.4
  • 192
    • 0030795033 scopus 로고    scopus 로고
    • Human cDNA encoding a novel TGF-beta superfamily protein highly expressed in placenta
    • Yokoyama-Kobayashi M., Saeki M., Sekine S. and Kato S. (1997). Human cDNA encoding a novel TGF-beta superfamily protein highly expressed in placenta. J. Biochem. (Tokyo) 122, 622-626.
    • (1997) J. Biochem. (Tokyo) , vol.122 , pp. 622-626
    • Yokoyama-Kobayashi, M.1    Saeki, M.2    Sekine, S.3    Kato, S.4
  • 193
    • 13444306377 scopus 로고    scopus 로고
    • Crosstalk between cancer cells and bone microenvironment in bone metastasis
    • Yoneda T. and Hiraga T. (2005). Crosstalk between cancer cells and bone microenvironment in bone metastasis. Biochem. Biophys. Res. Commun. 328, 679-687.
    • (2005) Biochem. Biophys. Res. Commun , vol.328 , pp. 679-687
    • Yoneda, T.1    Hiraga, T.2
  • 197
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • Zeisberg M., Hanai J., Sugimoto H., Mammoto T., Charytan D., Strutz F. and Kalluri R. (2003). BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat. Med. 9, 964-968.
    • (2003) Nat. Med , vol.9 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3    Mammoto, T.4    Charytan, D.5    Strutz, F.6    Kalluri, R.7
  • 198
    • 14844290237 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney
    • Zeisberg M., Shah A.A. and Kalluri R. (2005). Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J. Biol. Chem. 280, 8094-8100.
    • (2005) J. Biol. Chem , vol.280 , pp. 8094-8100
    • Zeisberg, M.1    Shah, A.A.2    Kalluri, R.3
  • 199
    • 0037169574 scopus 로고    scopus 로고
    • Effects of recombinant human bone morphogenic protein-2 and hyaluronic acid on invasion of brain glioma in vivo
    • Zhang X., Wu J., Li X., Fu L, Gao D., Bai H. and Liu X. (2002). Effects of recombinant human bone morphogenic protein-2 and hyaluronic acid on invasion of brain glioma in vivo. Zhonghua Yi Xue Za Zhi 82, 90-93.
    • (2002) Zhonghua Yi Xue Za Zhi , vol.82 , pp. 90-93
    • Zhang, X.1    Wu, J.2    Li, X.3    Fu, L.4    Gao, D.5    Bai, H.6    Liu, X.7
  • 200
    • 0033549789 scopus 로고    scopus 로고
    • A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation
    • Zhu H., Kavsak P., Abdollah S., Wrana J.L. and Thomsen G.H. (1999). A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. Nature 400, 687-693.
    • (1999) Nature , vol.400 , pp. 687-693
    • Zhu, H.1    Kavsak, P.2    Abdollah, S.3    Wrana, J.L.4    Thomsen, G.H.5
  • 201
    • 33744785946 scopus 로고    scopus 로고
    • Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer activity in vitro
    • Zhu W., Kim J., Cheng C., Rawlins B.A., Boachie-Adjei O., Crystal R.G. and Hidaka C. (2006). Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer activity in vitro. Bone 39, 61-71.
    • (2006) Bone , vol.39 , pp. 61-71
    • Zhu, W.1    Kim, J.2    Cheng, C.3    Rawlins, B.A.4    Boachie-Adjei, O.5    Crystal, R.G.6    Hidaka, C.7
  • 202
    • 0029876835 scopus 로고    scopus 로고
    • Requirement for BMP signaling in interdigital apoptosis and scale formation
    • Zou H. and Niswander L. (1996). Requirement for BMP signaling in interdigital apoptosis and scale formation. Science 272, 738-741.
    • (1996) Science , vol.272 , pp. 738-741
    • Zou, H.1    Niswander, L.2
  • 203
    • 3042778695 scopus 로고    scopus 로고
    • A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways
    • Zuzarte-Luis V., Montero J.A., Rodriguez-Leon J., Merino R., Rodriguez-Rey J.C. and Hurle J.M. (2004). A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways. Dev. Biol. 272, 39-52.
    • (2004) Dev. Biol , vol.272 , pp. 39-52
    • Zuzarte-Luis, V.1    Montero, J.A.2    Rodriguez-Leon, J.3    Merino, R.4    Rodriguez-Rey, J.C.5    Hurle, J.M.6


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