Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 5, 2005, Pages 1454-1459

  Javed, Amjad ^a   Barnes, George L ^b   Pratap, Jitesh ^a   Antkowiak, Tomasz ^a   Gerstenfeld, Louis C ^b   Van Wijnen, Andre J ^a   Stein, Janet L ^a   Lian, Jane B ^a   Stein, Gary S ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Gene expression; Intranuclear organization; Nuclear matrix

Indexed keywords

COLLAGENASE 3; TRANSCRIPTION FACTOR RUNX2; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL CULTURE; CELL NUCLEUS MATRIX; COCULTURE; CONTROLLED STUDY; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; OSTEOLYSIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACTIVE TRANSPORT, CELL NUCLEUS; BASE SEQUENCE; BINDING SITES; BONE NEOPLASMS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; COLLAGENASES; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CORE BINDING FACTOR ALPHA SUBUNITS; DNA PRIMERS; DNA, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; MATRIX METALLOPROTEINASE 13; NEOPLASM METASTASIS; NEOPLASM PROTEINS; OSTEOGENESIS; OSTEOLYSIS; POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS;

EID: 13444306168     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0409121102     Document Type: Article

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