-
1
-
-
21344443319
-
Bone morphogenetic proteins in development and homeostasis of kidney
-
Simic P, Vukicevic S. Bone morphogenetic proteins in development and homeostasis of kidney. Cytokine Growth Factor Rev 2005;16:299-308.
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 299-308
-
-
Simic, P.1
Vukicevic, S.2
-
2
-
-
0030218004
-
Bone morphogenetic proteins in development
-
Hogan BL. Bone morphogenetic proteins in development. Curr Opin Genet Dev 1996;6:432-8.
-
(1996)
Curr Opin Genet Dev
, vol.6
, pp. 432-438
-
-
Hogan, B.L.1
-
3
-
-
0031687841
-
Intracellular signaling of osteogenic protein-1 through Smad5 activation
-
Tamaki K, Souchelnytskyi S, Itoh S, et al. Intracellular signaling of osteogenic protein-1 through Smad5 activation. J Cell Physiol 1998;177:355-63.
-
(1998)
J Cell Physiol
, vol.177
, pp. 355-363
-
-
Tamaki, K.1
Souchelnytskyi, S.2
Itoh, S.3
-
4
-
-
0037862003
-
New intracellular components of bone morphogenetic protein/Smad signaling cascades
-
Zwijsen A, Verschueren K, Huylebroeck D. New intracellular components of bone morphogenetic protein/Smad signaling cascades. FEBS Lett 2003;546:133-9.
-
(2003)
FEBS Lett
, vol.546
, pp. 133-139
-
-
Zwijsen, A.1
Verschueren, K.2
Huylebroeck, D.3
-
5
-
-
21344455768
-
BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling cross-talk
-
Miyazono K, Maeda S, Imamura T. BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine Growth Factor Rev 2005;16:251-63.
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 251-263
-
-
Miyazono, K.1
Maeda, S.2
Imamura, T.3
-
6
-
-
0028574322
-
Osteogenic protein-1 (BMP-7)inhibits cell proliferation and stimulates the expression of markers characteristic of osteoblast phenotype in rat osteosarcoma (17/2.8) cells
-
Maliakal JC, Asahina I, Hauschka PV, Sampath TK. Osteogenic protein-1 (BMP-7)inhibits cell proliferation and stimulates the expression of markers characteristic of osteoblast phenotype in rat osteosarcoma (17/2.8) cells. Growth Factors 1994;11:227-34.
-
(1994)
Growth Factors
, vol.11
, pp. 227-234
-
-
Maliakal, J.C.1
Asahina, I.2
Hauschka, P.V.3
Sampath, T.K.4
-
7
-
-
0030885311
-
Osteogenic protein-1 and insulin-like growth factor I synergistically stimulate rat osteoblastic cell differentiation and proliferation
-
Yeh LC, Adamo ML, Olson MS, Lee JC. Osteogenic protein-1 and insulin-like growth factor I synergistically stimulate rat osteoblastic cell differentiation and proliferation. Endocrinology 1997;138:4181-90.
-
(1997)
Endocrinology
, vol.138
, pp. 4181-4190
-
-
Yeh, L.C.1
Adamo, M.L.2
Olson, M.S.3
Lee, J.C.4
-
8
-
-
11244256523
-
BMP signals inhibit proliferation and in vivo tumor growth of androgen-insensitive prostate carcinoma cells
-
Miyazaki H, Watabe T, Kitamura T, Miyazono K. BMP signals inhibit proliferation and in vivo tumor growth of androgen-insensitive prostate carcinoma cells. Oncogene 2004;23:9326-35.
-
(2004)
Oncogene
, vol.23
, pp. 9326-9335
-
-
Miyazaki, H.1
Watabe, T.2
Kitamura, T.3
Miyazono, K.4
-
9
-
-
0034810710
-
BMP-7-induced cell cycle arrest of anaplastic thyroid carcinoma cells via p21(CIP1)and p27(KIP1)
-
Franzen A, Heldin NE. BMP-7-induced cell cycle arrest of anaplastic thyroid carcinoma cells via p21(CIP1)and p27(KIP1). Biochem Biophys Res Commun 2001;285:773-81.
-
(2001)
Biochem Biophys Res Commun
, vol.285
, pp. 773-781
-
-
Franzen, A.1
Heldin, N.E.2
-
10
-
-
33646271828
-
Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathways
-
Yang S, Lim M, Pham LK, et al. Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathways. Cancer Res 2006;66:4285-90.
-
(2006)
Cancer Res
, vol.66
, pp. 4285-4290
-
-
Yang, S.1
Lim, M.2
Pham, L.K.3
-
11
-
-
33644748121
-
Bone morphogenetic protein 7 is widely overexpressed in primary breast cancer
-
Alarmo EL, Rauta J, Kauraniemi P, Karhu R, Kuukasjarvi T, Kallioniemi A. Bone morphogenetic protein 7 is widely overexpressed in primary breast cancer. Genes Chromosomes Cancer 2006;45:411-9.
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 411-419
-
-
Alarmo, E.L.1
Rauta, J.2
Kauraniemi, P.3
Karhu, R.4
Kuukasjarvi, T.5
Kallioniemi, A.6
-
12
-
-
0037439923
-
Overexpression of a dominant negative type II bone morphogenetic protein receptor inhibits the growth of human breast cancer cells
-
Pouliot F, Blais A, Labrie C. Overexpression of a dominant negative type II bone morphogenetic protein receptor inhibits the growth of human breast cancer cells. Cancer Res 2003;63:277-81.
-
(2003)
Cancer Res
, vol.63
, pp. 277-281
-
-
Pouliot, F.1
Blais, A.2
Labrie, C.3
-
13
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-25.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
el-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
-
14
-
-
0027459198
-
mdm2 expression is induced by wild type p53 activity
-
Barak Y, Juven T, Haffner R, Oren M. mdm2 expression is induced by wild type p53 activity. EMBO J 1993;12:461-8.
-
(1993)
EMBO J
, vol.12
, pp. 461-468
-
-
Barak, Y.1
Juven, T.2
Haffner, R.3
Oren, M.4
-
15
-
-
14044251523
-
The C terminus of p53 family proteins is a cell fate determinant
-
Harms KL, Chen X. The C terminus of p53 family proteins is a cell fate determinant. Mol Cell Biol 2005;25:2014-30.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2014-2030
-
-
Harms, K.L.1
Chen, X.2
-
16
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
Wu GS, Burns TF, McDonald ER III, et al. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 1997;17:141-3.
-
(1997)
Nat Genet
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald III, E.R.3
-
17
-
-
0037075898
-
Activation of the p53 tumor suppressor protein
-
Vousden KH. Activation of the p53 tumor suppressor protein. Biochim Biophys Acta 2002;1602:47-59.
-
(2002)
Biochim Biophys Acta
, vol.1602
, pp. 47-59
-
-
Vousden, K.H.1
-
18
-
-
0029814061
-
Anti-apoptotic activity of low levels of wild-type p53
-
Lassus P, Ferlin M, Piette J, Hibner U. Anti-apoptotic activity of low levels of wild-type p53. EMBO J 1996;15:4566-73.
-
(1996)
EMBO J
, vol.15
, pp. 4566-4573
-
-
Lassus, P.1
Ferlin, M.2
Piette, J.3
Hibner, U.4
-
19
-
-
13944283783
-
p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway
-
Park WR, Nakamura Y. p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway. Cancer Res 2005;65:1197-206.
-
(2005)
Cancer Res
, vol.65
, pp. 1197-1206
-
-
Park, W.R.1
Nakamura, Y.2
-
20
-
-
28644447272
-
The antioxidant function of the p53 tumor suppressor
-
Sablina AA, Budanov AV, Ilyinskaya GV, Agapova LS, Kravchenko JE, Chumakov PM. The antioxidant function of the p53 tumor suppressor. Nat Med 2005;11:1306-13.
-
(2005)
Nat Med
, vol.11
, pp. 1306-1313
-
-
Sablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
Agapova, L.S.4
Kravchenko, J.E.5
Chumakov, P.M.6
-
21
-
-
33644752095
-
Myosin VI is a mediator of the p53-dependent cell survival pathway
-
Jung EJ, Liu G, Zhou W, Chen X. Myosin VI is a mediator of the p53-dependent cell survival pathway. Mol Cell Biol 2006;26:2175-86.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2175-2186
-
-
Jung, E.J.1
Liu, G.2
Zhou, W.3
Chen, X.4
-
22
-
-
0033594491
-
p63 is a p53 homologue required for limb and epidermal morphogenesis
-
Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 1999;398:708-13.
-
(1999)
Nature
, vol.398
, pp. 708-713
-
-
Mills, A.A.1
Zheng, B.2
Wang, X.J.3
Vogel, H.4
Roop, D.R.5
Bradley, A.6
-
23
-
-
17544363909
-
p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
-
Yang A, Walker N, Bronson R, et al. p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature 2000;404:99-103.
-
(2000)
Nature
, vol.404
, pp. 99-103
-
-
Yang, A.1
Walker, N.2
Bronson, R.3
-
24
-
-
0346725958
-
ΔNp73β is active in transactivation and growth suppression
-
Liu G, Nozell S, Xiao H, Chen X. ΔNp73β is active in transactivation and growth suppression. Mol Cell Biol 2004;24:487-501.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 487-501
-
-
Liu, G.1
Nozell, S.2
Xiao, H.3
Chen, X.4
-
25
-
-
0041302159
-
Characterization of p73 functional domains necessary for transactivation and growth suppression
-
Nozell S, Wu Y, McNaughton K, et al. Characterization of p73 functional domains necessary for transactivation and growth suppression. Oncogene 2003;22:4333-47.
-
(2003)
Oncogene
, vol.22
, pp. 4333-4347
-
-
Nozell, S.1
Wu, Y.2
McNaughton, K.3
-
26
-
-
0034704151
-
Definition of the p53 functional domains necessary for inducing apoptosis
-
Zhu J, Zhang S, Jiang J, Chen X. Definition of the p53 functional domains necessary for inducing apoptosis. J Biol Chem 2000;275:39927-34.
-
(2000)
J Biol Chem
, vol.275
, pp. 39927-39934
-
-
Zhu, J.1
Zhang, S.2
Jiang, J.3
Chen, X.4
-
27
-
-
33646371246
-
GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner
-
Yan W, Chen X. GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner. J Biol Chem 2006;281:7856-62.
-
(2006)
J Biol Chem
, vol.281
, pp. 7856-7862
-
-
Yan, W.1
Chen, X.2
-
29
-
-
10744219596
-
Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector
-
van de Wetering M, Oving I, Muncan V, et al. Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector. EMBO Rep 2003;4:609-15.
-
(2003)
EMBO Rep
, vol.4
, pp. 609-615
-
-
van de Wetering, M.1
Oving, I.2
Muncan, V.3
-
30
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002;296:550-3.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
31
-
-
0038269028
-
The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein
-
Liu G, Xia T, Chen X. The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein. J Biol Chem 2003;278:17557-65.
-
(2003)
J Biol Chem
, vol.278
, pp. 17557-17565
-
-
Liu, G.1
Xia, T.2
Chen, X.3
-
32
-
-
0037075228
-
p21B, a variant of p21(Waf1/Cip1), is induced by the p53 family
-
Nozell S, Chen X. p21B, a variant of p21(Waf1/Cip1), is induced by the p53 family. Oncogene 2002;21:1285-94.
-
(2002)
Oncogene
, vol.21
, pp. 1285-1294
-
-
Nozell, S.1
Chen, X.2
-
33
-
-
32044449228
-
DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation
-
Liu G, Chen X. DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation. Mol Cell Biol 2006;26:1398-413.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 1398-1413
-
-
Liu, G.1
Chen, X.2
-
34
-
-
0029033333
-
p53, through p21 (WAF1/CIP1), induces cyclin D1 synthesis
-
Chen X, Bargonetti J, Prives C. p53, through p21 (WAF1/CIP1), induces cyclin D1 synthesis. Cancer Res 1995;55:4257-63.
-
(1995)
Cancer Res
, vol.55
, pp. 4257-4263
-
-
Chen, X.1
Bargonetti, J.2
Prives, C.3
-
35
-
-
0032557649
-
Identification of a novel p53 functional domain that is necessary for mediating apoptosis
-
Zhu J, Zhou W, Jiang J, Chen X. Identification of a novel p53 functional domain that is necessary for mediating apoptosis. J Biol Chem 1998;273:13030-6.
-
(1998)
J Biol Chem
, vol.273
, pp. 13030-13036
-
-
Zhu, J.1
Zhou, W.2
Jiang, J.3
Chen, X.4
-
36
-
-
0028048773
-
Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor
-
Johansen FE, Prywes R. Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor. Mol Cell Biol 1994;14:5920-8.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5920-5928
-
-
Johansen, F.E.1
Prywes, R.2
-
37
-
-
21344467705
-
Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells
-
Yang S, Zhong C, Frenkel B, Reddi AH, Roy-Burman P. Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells. Cancer Res 2005;65:5769-77.
-
(2005)
Cancer Res
, vol.65
, pp. 5769-5777
-
-
Yang, S.1
Zhong, C.2
Frenkel, B.3
Reddi, A.H.4
Roy-Burman, P.5
-
38
-
-
34249036783
-
A comprehensive expression survey of bone morphogenetic proteins in breast cancer highlights the importance of BMP4 and BMP7
-
Alarmo EL, Kuukasjarvi T, Karhu R, Kallioniemi A. A comprehensive expression survey of bone morphogenetic proteins in breast cancer highlights the importance of BMP4 and BMP7. Breast Cancer Res Treat 2007;103:239-46.
-
(2007)
Breast Cancer Res Treat
, vol.103
, pp. 239-246
-
-
Alarmo, E.L.1
Kuukasjarvi, T.2
Karhu, R.3
Kallioniemi, A.4
-
39
-
-
34249043939
-
Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: Implications of p53 mutation or isoform expression on breast cancer cell invasion
-
Mehta SA, Christopherson KW, Bhat-Nakshatri P, et al. Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion. Oncogene 2006;26:3319-37.
-
(2006)
Oncogene
, vol.26
, pp. 3319-3337
-
-
Mehta, S.A.1
Christopherson, K.W.2
Bhat-Nakshatri, P.3
-
41
-
-
0035651187
-
Fate alteration of neuroepithelial cells from neurogenesis to astrocytogenesis by bone morphogenetic proteins
-
Yanagisawa M, Takizawa T, Ochiai W, Uemura A, Nakashima K, Taga T. Fate alteration of neuroepithelial cells from neurogenesis to astrocytogenesis by bone morphogenetic proteins. Neurosci Res 2001;41:391-6.
-
(2001)
Neurosci Res
, vol.41
, pp. 391-396
-
-
Yanagisawa, M.1
Takizawa, T.2
Ochiai, W.3
Uemura, A.4
Nakashima, K.5
Taga, T.6
-
42
-
-
0037085441
-
Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
-
Korchynskyi O, ten Dijke P. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J Biol Chem 2002;277:4883-91.
-
(2002)
J Biol Chem
, vol.277
, pp. 4883-4891
-
-
Korchynskyi, O.1
ten Dijke, P.2
-
43
-
-
33644813656
-
BMP-7 opposes TGF-β1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2
-
Izumi N, Mizuguchi S, Inagaki Y, et al. BMP-7 opposes TGF-β1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2. Am J Physiol Lung Cell Mol Physiol 2006;290:L120-6.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
-
-
Izumi, N.1
Mizuguchi, S.2
Inagaki, Y.3
-
44
-
-
33746437215
-
Transcriptional profiling of MCF7 breast cancer cells in response to 5-fluorouracil: Relationship with cell cycle changes and apoptosis, and identification of novel targets of p53
-
Hernandez-Vargas H, Ballestar E, Carmona-Saez P, et al. Transcriptional profiling of MCF7 breast cancer cells in response to 5-fluorouracil: relationship with cell cycle changes and apoptosis, and identification of novel targets of p53. Int J Cancer 2006;119:1164-75.
-
(2006)
Int J Cancer
, vol.119
, pp. 1164-1175
-
-
Hernandez-Vargas, H.1
Ballestar, E.2
Carmona-Saez, P.3
-
45
-
-
33646711244
-
p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation
-
Laurikkala J, Mikkola ML, James M, Tummers M, Mills AA, Thesleff I. p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development 2006;133:1553-63.
-
(2006)
Development
, vol.133
, pp. 1553-1563
-
-
Laurikkala, J.1
Mikkola, M.L.2
James, M.3
Tummers, M.4
Mills, A.A.5
Thesleff, I.6
-
46
-
-
1642523489
-
Helix-loop-helix proteins in mammary gland development and breast cancer
-
Desprez PY, Sumida T, Coppe JP. Helix-loop-helix proteins in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia 2003;8:225-39.
-
(2003)
J Mammary Gland Biol Neoplasia
, vol.8
, pp. 225-239
-
-
Desprez, P.Y.1
Sumida, T.2
Coppe, J.P.3
-
48
-
-
7644235254
-
A role for Id proteins in mammary gland physiology and tumorigenesis
-
de Candia P, Benera R, Solit DB. A role for Id proteins in mammary gland physiology and tumorigenesis. Adv Cancer Res 2004;92:81-94.
-
(2004)
Adv Cancer Res
, vol.92
, pp. 81-94
-
-
de Candia, P.1
Benera, R.2
Solit, D.B.3
-
49
-
-
0034332415
-
Lactation defect in mice lacking the helix-loop-helix inhibitor Id2
-
Mori S, Nishikawa SI, Yokota Y. Lactation defect in mice lacking the helix-loop-helix inhibitor Id2. EMBO J 2000;19:5772-81.
-
(2000)
EMBO J
, vol.19
, pp. 5772-5781
-
-
Mori, S.1
Nishikawa, S.I.2
Yokota, Y.3
-
50
-
-
0242526142
-
Role of Id-2 in the maintenance of a differentiated and noninvasive phenotype in breast cancer cells
-
Itahana Y, Singh J, Sumida T, et al. Role of Id-2 in the maintenance of a differentiated and noninvasive phenotype in breast cancer cells. Cancer Res 2003;63:7098-105.
-
(2003)
Cancer Res
, vol.63
, pp. 7098-7105
-
-
Itahana, Y.1
Singh, J.2
Sumida, T.3
|