Bone morphogenetic proteins: An unconventional approach to isolation of first mammalian morphogens

Cytokine and Growth Factor Reviews

Volumn 8, Issue 1, 1997, Pages 11-20

  Reddi, A Hari ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cartilage; Chemotaxis; Norphogenesis; Pleiotropy

Indexed keywords

BMP RECEPTOR; BONE MORPHOGENETIC PROTEIN; CELL SURFACE RECEPTOR; MORPHOGEN;

ADULT; ANIMAL; BIOLOGICAL MODEL; BONE; BONE DEVELOPMENT; CARTILAGE; CELL INTERACTION; CHONDROGENESIS; EMBRYO DEVELOPMENT; EPITHELIUM CELL; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MAMMAL; MESENCHYME; MOUSE; NONHUMAN; PHENOTYPE; PHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN ISOLATION; SHORT SURVEY; SIGNAL TRANSDUCTION;

ADULT; ANIMALS; BONE AND BONES; BONE DEVELOPMENT; BONE MORPHOGENETIC PROTEIN RECEPTORS; BONE MORPHOGENETIC PROTEINS; CARTILAGE; HUMANS; MICE; MODELS, BIOLOGICAL; PHENOTYPE; RECEPTORS, CELL SURFACE; RECEPTORS, GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 0031105160     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6101(96)00049-4     Document Type: Short Survey

References (84)

1. Reddi AH. Bone and cartilage differentiation. Curr Opin Genet Dev 1994, 4, 737-744.
2. Nüsslein-Volhard C, Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature 1980, 287, 795-801.
3. Ingham PW, Arias AM. Boundaries and fields in early embryos. Cell 1992, 68, 221-235.
4. Lee JJ, von Kessler DP, Parks, S, Beachy PA. Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog. Cell 1992, 71, 33-50.
5. Riddle RD, Johnson RL, Laufer E, Tabin C. Sonic hedgehog mediates the polarizing activity of ZPA. Cell 1993, 75, 1401-1416.
6. Senn N. On the healing of aseptic bone cavities by implantation of antiseptic decalcified bone. Am J Med Sci 1989, 98, 219-243.
7. Lacroix P. Recent investigation on the growth of bone. Nature 1945, 156, 576.
8. Urist MR. Bone: Formation by autoinduction. Science 1965, 150, 893-899.
9. Reddi AH, Huggins CB. Biochemical sequences in the transformation of normal fibroblasts in adolescent rat. Proc Natl Acad Sci USA 1972, 69, 1601-1605.
10. Reddi AH. Cell biology and biochemistry of endochondral bone development. Coll Rel Res 1981, 1, 209-226.
11. Reddi AH. Extracellular matrix and development. In Extracellular Matrix Biochemistry, KA Piez, Reddi AH, eds. New York, Elsevier, 1984, 375-412.
12. Rath NC, Reddi AH. Collagenous bone matrix is a local mitogen. Nature 1979, 278, 855-857.
13. Sampath TK, Reddi AH. Dissociative extraction and reconstitution of bone matrix components involved in local bone differentiation. Proc Natl Acad Sci USA 1981, 78, 7599-7603.
14. Sampath TK, Reddi AH. Homology of bone-inductive proteins from human, monkey, bovine, and rat extracellular matrix. Proc Natl Acad Sci USA 1983, 80, 6591-6595.
15. Luyten FP, Cunningham NS, Ma S, et al. Purification and partial amino acid sequence of osteogenin, a protein initiating bone differentiation. J Biol Chem 1989, 264, 13,377-13,380.
16. Sporn MB, Roberts AD. Peptide growth factors and their receptors. In Handbook of Experimental Pharmacology. Heidelberg, Springer, 1990.
17. Wozney JM, Rosen V, Celeste AJ, et al. Novel regulators of bone formation: Molecular clones and activities. Science 1988, 242, 1528-1534.
18. Özkaynak E, Schnegelsberg PNJ, Jin DF, et al. Osteogenic Protein-2. J Biol Chem 1992, 267, 25,220-25,227.
19. Zhou XI, Sasaki H, Lowe L, et al. Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation. Nature 1993, 361, 543-547.
20. Lowe L, Supp DM, Sampath K, et al. Conserved left-right asymmetry of nodal expression and alterations in murine situs inverus. Nature 1996, 381, 158-161.
21. Collignon J, Varlet I, Robertson EJ. Relationship between asymmetric nodal expression and the direction of embryonic turning. Nature 1996, 381, 155-158.
22. Meno C, Saijoh Y, Fujii H. Left-right asymmetric expression of the TGF-β family member lefty in mouse embyros. Nature 1996, 381, 151-155.
23. Griffith D, Keck PC, Sampath TK, Rueger DC, Carlson WD. Three dimensional structure of recombinant human osteogenic protein-1: Structural paradigm for the transforming growth factor-β superfamily. Proc Natl Acad Sci USA 1996, 93, 878-883.
24. 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors. Structures 1993, 1, 153-159.
25. Shulnegger MP, Grütter MG. Refined structure of human transforming growth factor β2 at 1.95 A resolution. J Molec Biol 1993, 231, 445-4458.
26. Chang SC, Hoang B, Thomas JT, et al. Cartilage-derived morphogenetic proteins. J Biol Chem 1994, 269, 28,227-28,234.
27. Lyons KM, Pelton RW, Hogan BLM. Organogenesis and pattern formation in the mouse: RNA distribution patterns support a role for BMP-2. Development 1990, 109, 833-844.
28. Lyons KM, Hogan BLM, Robertson EJ. Colocalization of BMP-2 and BMP-7 RNA suggest that these factors cooperatively act in tissue interactions during murine development. Mechanisms Dev 1995, 50, 71-83.
29. Carrington JL, Chen P, Yanagishita M, Reddi AH. Osteogenin (BMP-3) stimulates cartilage formation by chick limb bud cells in vitro. Dev Biol 1991, 146, 406-415.
30. 2. Exp Cell Res 1991, 195, 509-515.
31. Duprez D, Bell EJ, Richardson MK, et al. Overexpression of BMP-2 and BMP-4 alters the size and shape of developing skeletal elements in the chick limb. Mechanisms Dev 1996, 57, 145-157.
32. Duprez DM, Coltey M, Amthor H, Brickell PM, Tickle C. Bone morphogenetic protein-2 (BMP-2) inhibits muscle development and promotes cartilage formation in chick limb bud cultures. Dev Biol 1996, 174, 448-452.
33. Krumluf, R. Hox genes in vertebrate development. Cell 1994, 78, 191-201.
34. Ladher R, Mohun TJ, Smith JC, Snape AM. Xom: a Xenopus homeobox gene that mediates the early effects of BMP-4. Development 1996, 122, 2385-2394.
35. Luyten FP, Yu YM, Yanagishita M, Vukicevic S, Hammonds RG, Reddi AH. Natural bovine osteogenin and recombinant BMP-2B are equipotent in the maintenance of proteoglycans in bovine articular cartilage explant cultures. J Biol Chem 1992, 267, 3685-3691.
36. Lietman SA, Yanagishita M, Sampath K, Reddi AH. Stimulation of proteoglycan synthesis in porcine cartilage explants by recombinant osteogenic protein-1 (Bone morphogenetic protein-7). J Bone Joint Surg 1997, (in press).
37. 1 mRNA expression. Proc Natl Acad Sci USA 1992, 89, 11,740-11,744.
38. Paralkar VM, Nandedkar AKW, Pointer RH, Kleinman HK, Reddi AH. Interaction of osteogenin, a heparin binding bone morphogenetic protein with type IV collagen. J Biol Chem 1990, 265, 17,281-17,284.
39. Paralkar VM, Vukicevic S, Reddi AH. Transforming growth factor-β type I binds to collagen IV of basement membrane matrix: Implications for development. Dev Biol 1991, 143, 303-308.
40. Green JBA, New HV, Smith JC. Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm. Cell 1992, 71, 731-739.
41. St Johnston D, Nüsslein-Volhard C. The origin of pattern formation and polarity in the Drosophila embryo. Cell 1992, 68, 201-219.
42. Paralkar VM, Weeks BS, Yu YM, Kleinman HK, Reddi AH. Recombinant human bone morphogenetic protein 2B stimulates PC12 cell differentiation: Potentiation and binding to type IV collagen. J Cell Biol 1992, 119, 1721-1728.
43. Vukicevic S, Luyten FP, Kleinman HK, Reddi AH. Differentiation of canalicular cell processes in bone cells by basement membrane matrix components: Regulation by discrete domains of laminin. Cell 1990, 63, 437-445.
44. Hemmati-Brivanlou A, Melton DA. Inhibition of activin receptor signaling promotes neuralization in Xenopus. Cell 1994, 77, 273-281.
45. Michel U, Farnworth P, Findlay JK. Follistatins: more than follicle-stimulating hormone suppressing proteins. Molec Cell Endocr 1993, 91, 1-11.
46. Hemmati-Brivanlou A, Kelly OG, Melton DA. Follistatin, an antagonist of activin is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 1994, 77, 283-295.
47. Piccolo S, Sasai Y, Lu B, De Robertis EM. Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 1996, 86, 589-598.
48. Zimmerman LB, Jesus-Escobar JM, Harland RM. The Spemann organizer signal Noggin binds and inactivates bone morphogenetic protein-4. Cell 1996, 86, 599-606.
49. Holley SA, Jackson PD, Sasai Y, et al. A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin. Nature 1995, 376, 249-253.
50. Grobstein C. Mechanisms of organogenetic tissue interaction. Natl Cancer Inst Monograph 1967, 26, 279-299.
51. Vaahtokari A, Aberg T, Jernvall J, Keraten S, Thesleff I. The enamel knot as a signaling center in the developing mouse tooth. Mechanisms Dev 1996, 54, 39-43.
52. Nakashima M, Nagasawa H, Yamada Y, Reddi AH. Regulatory role of TGF-β, BMP-2 and BMP-4 on gene expression of extracellular matrix protein and differentiation of dental pulp cells. Dev Biol 1994, 162, 18-28.
53. Phippard DJ, Weber-Hall SJ, Sharpe PT, et al. Regulation of Msx-1, Msx-2, BMP-2 and BMP-4 during foetal and postnatal mammary gland development. Development 1996, 122, 2729-2737.
54. Winnier G, Blessing M, Labosky PA, Hogan BLM. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev 1996, 9, 2105-2116.
55. Bellusci S, Henderson R, Winnier G, Oikawa T, Hogan BLM. Evidence from novel expression and targeted misexpression that BMP-4 plays a role in mouse embryonic lung morphogenesis. Development 1976, 122, 1693-1702.
56. Gitelman SE, Kirk M, Ye JQ, Filvaroff EH, Kahn AJ, Derynck R. Vgr-1/BMP-6 induces osteoblastic differentiation of pluripotential mesenchymal cells. Cell Growth Diff 1995, 6, 827-836.
57. Blessing M, Schirmacher P, Kaiser S. Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on pattern of transgenic expression and formation of psoriatic lesions. J Cell Biol 1996, 135, 227-239.
58. Dudley AT, Lyons KM, Robertson EJ. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev 1996, 9, 2795-2807.
59. Luo G, Hofmann C, Broncker ALJI, Sohucki M, Bradley A, Karsenty G. BMP-7 is an inducer of nephrogenesis and is also required for eye development and skeletal patterning. Genes Dev 1995, 9, 28,028-2820.
60. Vukicevic S, Kopp JB, Luyten FP, Sampath K. Induction of nephrogenic mesenchyme by osteogenic protein-1 (bone morphogenetic protein-7). Proc Natl Acad Sci USA 1996, 92, 9021-9026.
61. Solursh M, Langille RM, Wood J, Sampath TK. Osteogenic protein-1 is required for mammalian eye development. Biochem Biophys Res Commun 1996, 218, 438-443.
62. Song JJ, Celeste AJ, Kong FM, Jirtle RL, Rosen V, Thies RS. Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation. Endocrinology 1995, 136, 4293-4297.
63. Kessler E, Takahara K, Biniaminor L, Brusel M, Greenspan DS. Bone morphogenetic protein-1: the type I procollagen C-proteinase. Science 1996, 271, 360-362.
64. Li SW, Sieron AL, Fertala A, Hojima Y, Arnold WV, Prockop DJ. The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified as bone morphogenetic protein-1. Proc Natl Acad Sci USA 1996, 93, 5127-5130.
65. Reddi AH. BMP-1: resurrection as procollagen C-proteinase. Science 1996, 271, 463.
66. Yamashita H, ten Dijke P, Heldin CH, Miyazono K. Bone morphogenetic protein receptors. Bone 1996, 19, 569-574.
67. ten Dijke P, Yamashita H, Sampath TK, et al. Identification of type I receptor for OP-1 and BMP-4. J Biol Chem 1994, 269, 16,986-16,988.
68. Koenig BB, Cook JS, Wolsing DH. Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells. Molec Cell Biol 1994, 14, 5961-5974.
69. Yamashita H, ten Dijke P, Huylebrock D, et al. Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects. J Cell Biol 1995, 130, 217-226.
70. Nishitoh H, Ichijo H, Kimura M, et al. Identification of types 1 and II serine/threonine kinase receptors for growth differentiation factor-5. J Biol Chem 1996, 271, 21,345-21,352.
71. Liu F, Ventura F, Doody J, Massague J. Human type II receptors for bone morphogenetic proteins (BMPs): extension of the two-kinase receptors to the BMPs. Molec Cell Biol 1995, 15, 3479-3486.
72. Rosenzweig BL, Imamura T, Okadome T, et al. Cloning and characterization of human type II receptors for bone morphogenetic proteins. Proc Natl Acad Sci USA 1995, 92, 7632-7636.
73. Nohno T, Ishikawa T, Saito T, et al. Identification of human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with BMP-type 1 receptors. J Biol Chem 1995, 270, 22,522-22,526.
74. Sekelsky JJ, Newfield SJ, Raftery LA, Chartoff EH, Gelbart WM. Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 1995, 139, 1347-1358.
75. Savage C, Das P, Finelli AL, et al. Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor-β pathway components. Proc Natl Acad Sci USA 1996, 93, 790-794.
76. Derynck R, Gelbart WM, Harland RM, et al. Nomenclature: Vertebrate mediators of TGF-β family signals. Cell 1996, 87, 173.
77. Graff JM, Bansal A, Melton DA. Xenopus mad proteins transduce distinct subsets of signals for the TGF-β superfamily. Cell 1996, 85, 479-487.
78. Hoodless PA, Haerry T, Abdollah S, et al. MADR 1, a MAD related protein that functions in BMP-2 signaling pathways. Cell 1996, 85, 489-500.
79. Chen X, Rubock MJ, Whitman M. A transcriptional partner for MAD proteins in TGF-β signalling. Nature 1996, 383, 691-696.
80. Hahn SA, Schutte M, Hogue ATMS, et al. DPC 4, a candidate tumor suppressor gene at human chromosome 18q 21.1 Science 1996, 271, 350-353.
81. Lagna G, Hata A, Hemmati-Brivanlou A, Massague J. Partnership between DPC 4 and Smad proteins in TGF-β signalling pathways. Nature 1996, 383, 832-836.
82. Yamaguchi K, Shirakabe K, Shibuya H, et al. Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 1995, 270, 2008-2011.
83. Shibuya H, Tamaguchi K, Shirakabe K, et al. TAB 1: An activator of the TAK 1 MAPKKK in TGF-β signal transduction. Science 1996, 272, 1179-1182.
84. Moriguchi T, Kuroyamagi N, Yamaguchi K, et al. A novel kinase cascade mediated by mitogen-activated protein kinase Kinase 6 and MKK 3. J Biol Chem 1996, 271, 13,675-13.679.