-
1
-
-
0031685620
-
TGF-beta signal transduction
-
Massague J (1998) TGF-beta signal transduction. Annu Rev Biochem 67, 753 791.
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
2
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
Heldin CH, Miyazono K ten Dijke P (1997) TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465 471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
3
-
-
0036910425
-
Two major Smad pathways in TGF-beta superfamily signalling
-
Miyazawa K, Shinozaki M, Hara T, Furuya T Miyazono K (2002) Two major Smad pathways in TGF-beta superfamily signalling. Genes Cells 7, 1191 1204.
-
(2002)
Genes Cells
, vol.7
, pp. 1191-1204
-
-
Miyazawa, K.1
Shinozaki, M.2
Hara, T.3
Furuya, T.4
Miyazono, K.5
-
4
-
-
0842346190
-
Transforming growth factor-beta-related proteins: An ancestral and widespread superfamily of cytokines in metazoans
-
Herpin A, Lelong C Favrel P (2004) Transforming growth factor-beta-related proteins: an ancestral and widespread superfamily of cytokines in metazoans. Dev Comp Immunol 28, 461 485.
-
(2004)
Dev Comp Immunol
, vol.28
, pp. 461-485
-
-
Herpin, A.1
Lelong, C.2
Favrel, P.3
-
6
-
-
0024256133
-
Novel regulators of bone formation: Molecular clones and activities
-
Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ, Kriz RW, Hewick RM Wang EA (1988) Novel regulators of bone formation: molecular clones and activities. Science 242, 1528 1534.
-
(1988)
Science
, vol.242
, pp. 1528-1534
-
-
Wozney, J.M.1
Rosen, V.2
Celeste, A.J.3
Mitsock, L.M.4
Whitters, M.J.5
Kriz, R.W.6
Hewick, R.M.7
Wang, E.A.8
-
7
-
-
34250019537
-
Bone: Formation by autoinduction
-
Urist MR (1965) Bone: formation by autoinduction. Science 150, 893 899.
-
(1965)
Science
, vol.150
, pp. 893-899
-
-
Urist, M.R.1
-
8
-
-
0034128748
-
The family of bone morphogenetic proteins
-
Ducy P Karsenty G (2000) The family of bone morphogenetic proteins. Kidney Int 57, 2207 2214.
-
(2000)
Kidney Int
, vol.57
, pp. 2207-2214
-
-
Ducy, P.1
Karsenty, G.2
-
9
-
-
0036399170
-
Extracellular regulation of BMP signaling in vertebrates: A cocktail of modulators
-
Balemans W Van Hul W (2002) Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. Dev Biol 250, 231 250.
-
(2002)
Dev Biol
, vol.250
, pp. 231-250
-
-
Balemans, W.1
Van Hul, W.2
-
10
-
-
0029944441
-
Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors
-
ten Dijke P, Miyazono K Heldin CH (1996) Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Curr Opin Cell Biol 8, 139 145.
-
(1996)
Curr Opin Cell Biol
, vol.8
, pp. 139-145
-
-
Ten Dijke, P.1
Miyazono, K.2
Heldin, C.H.3
-
12
-
-
4544286802
-
Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction
-
Sebald W, Nickel J, Zhang JL Mueller TD (2004) Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction. Biol Chem 385, 697 710.
-
(2004)
Biol Chem
, vol.385
, pp. 697-710
-
-
Sebald, W.1
Nickel, J.2
Zhang, J.L.3
Mueller, T.D.4
-
13
-
-
0029985652
-
Formation and activation by phosphorylation of activin receptor complexes
-
Willis SA, Zimmerman CM, Li LI Mathews LS (1996) Formation and activation by phosphorylation of activin receptor complexes. Mol Endocrinol 10, 367 379.
-
(1996)
Mol Endocrinol
, vol.10
, pp. 367-379
-
-
Willis, S.A.1
Zimmerman, C.M.2
Li, L.I.3
Mathews, L.S.4
-
14
-
-
0029008597
-
Human type II receptor for bone morphogenic proteins (BMPs): Extension of the two-kinase receptor model to the BMPs
-
Liu F, Ventura F, Doody J Massague J (1995) Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs. Mol Cell Biol 15, 3479 3486.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3479-3486
-
-
Liu, F.1
Ventura, F.2
Doody, J.3
Massague, J.4
-
15
-
-
20344385511
-
A single residue of GDF-5 defines binding specificity to BMP receptor IB
-
Nickel J, Kotzsch A, Sebald W Mueller TD (2005) A single residue of GDF-5 defines binding specificity to BMP receptor IB. J Mol Biol 349, 933 947.
-
(2005)
J Mol Biol
, vol.349
, pp. 933-947
-
-
Nickel, J.1
Kotzsch, A.2
Sebald, W.3
Mueller, T.D.4
-
16
-
-
0031027637
-
A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis
-
Chang C, Wilson PA, Mathews LS Hemmati-Brivanlou A (1997) A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis. Development 124, 827 837.
-
(1997)
Development
, vol.124
, pp. 827-837
-
-
Chang, C.1
Wilson, P.A.2
Mathews, L.S.3
Hemmati-Brivanlou, A.4
-
17
-
-
1542357571
-
Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5
-
Mazerbourg S, Klein C, Roh J, Kaivo-Oja N, Mottershead DG, Korchynskyi O, Ritvos O Hsueh AJ (2004) Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5. Mol Endocrinol 18, 653 665.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 653-665
-
-
Mazerbourg, S.1
Klein, C.2
Roh, J.3
Kaivo-Oja, N.4
Mottershead, D.G.5
Korchynskyi, O.6
Ritvos, O.7
Hsueh, A.J.8
-
18
-
-
0032589736
-
Specificity of TGFbeta signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans
-
Krishna S, Maduzia LL Padgett RW (1999) Specificity of TGFbeta signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans. Development 126, 251 260.
-
(1999)
Development
, vol.126
, pp. 251-260
-
-
Krishna, S.1
Maduzia, L.L.2
Padgett, R.W.3
-
19
-
-
0028923022
-
An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo
-
Ruberte E, Marty T, Nellen D, Affolter M Basler K (1995) An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. Cell 80, 889 897.
-
(1995)
Cell
, vol.80
, pp. 889-897
-
-
Ruberte, E.1
Marty, T.2
Nellen, D.3
Affolter, M.4
Basler, K.5
-
20
-
-
0028907069
-
Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGF beta receptor family
-
Letsou A, Arora K, Wrana JL, Simin K, Twombly V, Jamal J, Staehling-Hampton K, Hoffmann FM, Gelbart WM, Massague J et al. (1995) Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF beta receptor family. Cell 80, 899 908.
-
(1995)
Cell
, vol.80
, pp. 899-908
-
-
Letsou, A.1
Arora, K.2
Wrana, J.L.3
Simin, K.4
Twombly, V.5
Jamal, J.6
Staehling-Hampton, K.7
Hoffmann, F.M.8
Gelbart, W.M.9
Massague, J.10
-
21
-
-
17644394929
-
Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo
-
Shimmi O, Umulis D, Othmer H O'Connor MB (2005) Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo. Cell 120, 873 886.
-
(2005)
Cell
, vol.120
, pp. 873-886
-
-
Shimmi, O.1
Umulis, D.2
Othmer, H.3
O'Connor, M.B.4
-
22
-
-
0032900499
-
The Drosophila activin receptor baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development
-
Brummel T, Abdollah S, Haerry TE, Shimell MJ, Merriam J, Raftery L, Wrana JL O'Connor MB (1999) The Drosophila activin receptor baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development. Genes Dev 13, 98 111.
-
(1999)
Genes Dev
, vol.13
, pp. 98-111
-
-
Brummel, T.1
Abdollah, S.2
Haerry, T.E.3
Shimell, M.J.4
Merriam, J.5
Raftery, L.6
Wrana, J.L.7
O'Connor, M.B.8
-
23
-
-
0037423389
-
TGF-beta signaling activates steroid hormone receptor expression during neuronal remodeling in the Drosophila brain
-
Zheng X, Wang J, Haerry TE, Wu AY, Martin J, O'Connor MB, Lee CH Lee T (2003) TGF-beta signaling activates steroid hormone receptor expression during neuronal remodeling in the Drosophila brain. Cell 112, 303 315.
-
(2003)
Cell
, vol.112
, pp. 303-315
-
-
Zheng, X.1
Wang, J.2
Haerry, T.E.3
Wu, A.Y.4
Martin, J.5
O'Connor, M.B.6
Lee, C.H.7
Lee, T.8
-
24
-
-
0034021776
-
Bone morphogenetic protein receptor complexes on the surface of live cells: A new oligomerization mode for serine/threonine kinase receptors
-
Gilboa L, Nohe A, Geissendorfer T, Sebald W, Henis YI Knaus P (2000) Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. Mol Biol Cell 11, 1023 1035.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 1023-1035
-
-
Gilboa, L.1
Nohe, A.2
Geissendorfer, T.3
Sebald, W.4
Henis, Y.I.5
Knaus, P.6
-
25
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas S, Rand MD Lake RJ (1999) Notch signaling: cell fate control and signal integration in development. Science 284, 770 776.
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
26
-
-
0141656297
-
Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1
-
Foletta VC, Lim MA, Soosairajah J, Kelly AP, Stanley EG, Shannon M, He W, Das S, Massague J Bernard O (2003) Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1. J Cell Biol 162, 1089 1098.
-
(2003)
J Cell Biol
, vol.162
, pp. 1089-1098
-
-
Foletta, V.C.1
Lim, M.A.2
Soosairajah, J.3
Kelly, A.P.4
Stanley, E.G.5
Shannon, M.6
He, W.7
Das, S.8
Massague, J.9
Bernard, O.10
-
27
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray SJ (2006) Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 7, 678 689.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
-
28
-
-
0026317981
-
The Drosophila RBP-J kappa gene encodes the binding protein for the immunoglobulin J kappa recombination signal sequence
-
Furukawa T, Kawaichi M, Matsunami N, Ryo H, Nishida Y Honjo T (1991) The Drosophila RBP-J kappa gene encodes the binding protein for the immunoglobulin J kappa recombination signal sequence. J Biol Chem 266, 23334 23340.
-
(1991)
J Biol Chem
, vol.266
, pp. 23334-23340
-
-
Furukawa, T.1
Kawaichi, M.2
Matsunami, N.3
Ryo, H.4
Nishida, Y.5
Honjo, T.6
-
29
-
-
0034633964
-
Notch signaling: A dance of proteins changing partners
-
Kadesch T (2000) Notch signaling: a dance of proteins changing partners. Exp Cell Res 260, 1 8.
-
(2000)
Exp Cell Res
, vol.260
, pp. 1-8
-
-
Kadesch, T.1
-
30
-
-
10744231139
-
Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells
-
Itoh F, Itoh S, Goumans MJ, Valdimarsdottir G, Iso T, Dotto GP, Hamamori Y, Kedes L, Kato M ten Dijke Part P (2004) Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells. Embo J 23, 541 551.
-
(2004)
Embo J
, vol.23
, pp. 541-551
-
-
Itoh, F.1
Itoh, S.2
Goumans, M.J.3
Valdimarsdottir, G.4
Iso, T.5
Dotto, G.P.6
Hamamori, Y.7
Kedes, L.8
Kato, M.9
Ten Dijke Part, P.10
-
31
-
-
0345166971
-
Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3
-
Blokzijl A, Dahlqvist C, Reissmann E, Falk A, Moliner A, Lendahl U Ibanez CF (2003) Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3. J Cell Biol 163, 723 728.
-
(2003)
J Cell Biol
, vol.163
, pp. 723-728
-
-
Blokzijl, A.1
Dahlqvist, C.2
Reissmann, E.3
Falk, A.4
Moliner, A.5
Lendahl, U.6
Ibanez, C.F.7
-
32
-
-
0037085287
-
The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways
-
Nohe A, Hassel S, Ehrlich M, Neubauer F, Sebald W, Henis YI Knaus P (2002) The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways. J Biol Chem 277, 5330 5338.
-
(2002)
J Biol Chem
, vol.277
, pp. 5330-5338
-
-
Nohe, A.1
Hassel, S.2
Ehrlich, M.3
Neubauer, F.4
Sebald, W.5
Henis, Y.I.6
Knaus, P.7
-
33
-
-
0033521529
-
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway
-
Yamaguchi K, Nagai S, Ninomiya-Tsuji J, Nishita M, Tamai K, Irie K, Ueno N, Nishida E, Shibuya H Matsumoto K (1999) XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. Embo J 18, 179 187.
-
(1999)
Embo J
, vol.18
, pp. 179-187
-
-
Yamaguchi, K.1
Nagai, S.2
Ninomiya-Tsuji, J.3
Nishita, M.4
Tamai, K.5
Irie, K.6
Ueno, N.7
Nishida, E.8
Shibuya, H.9
Matsumoto, K.10
-
34
-
-
23844455632
-
NRAGE mediates p38 activation and neural progenitor apoptosis via the bone morphogenetic protein signaling cascade
-
Kendall SE, Battelli C, Irwin S, Mitchell JG, Glackin CA Verdi JM (2005) NRAGE mediates p38 activation and neural progenitor apoptosis via the bone morphogenetic protein signaling cascade. Mol Cell Biol 25, 7711 7724.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 7711-7724
-
-
Kendall, S.E.1
Battelli, C.2
Irwin, S.3
Mitchell, J.G.4
Glackin, C.A.5
Verdi, J.M.6
-
35
-
-
0035955631
-
Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death
-
Jordan BW, Dinev D, LeMellay V, Troppmair J, Gotz R, Wixler L, Sendtner M, Ludwig S Rapp UR (2001) Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death. J Biol Chem 276, 39985 39989.
-
(2001)
J Biol Chem
, vol.276
, pp. 39985-39989
-
-
Jordan, B.W.1
Dinev, D.2
Lemellay, V.3
Troppmair, J.4
Gotz, R.5
Wixler, L.6
Sendtner, M.7
Ludwig, S.8
Rapp, U.R.9
-
36
-
-
0030968634
-
TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase
-
Shirakabe K, Yamaguchi K, Shibuya H, Irie K, Matsuda S, Moriguchi T, Gotoh Y, Matsumoto K Nishida E (1997) TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase. J Biol Chem 272, 8141 8144.
-
(1997)
J Biol Chem
, vol.272
, pp. 8141-8144
-
-
Shirakabe, K.1
Yamaguchi, K.2
Shibuya, H.3
Irie, K.4
Matsuda, S.5
Moriguchi, T.6
Gotoh, Y.7
Matsumoto, K.8
Nishida, E.9
-
37
-
-
4644369736
-
Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cells
-
Kuwajima T, Taniura H, Nishimura I Yoshikawa K (2004) Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cells. J Biol Chem 279, 40484 40493.
-
(2004)
J Biol Chem
, vol.279
, pp. 40484-40493
-
-
Kuwajima, T.1
Taniura, H.2
Nishimura, I.3
Yoshikawa, K.4
-
38
-
-
11244313831
-
Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis
-
Lee-Hoeflich ST, Causing CG, Podkowa M, Zhao X, Wrana JL Attisano L (2004) Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis. Embo J 23, 4792 4801.
-
(2004)
Embo J
, vol.23
, pp. 4792-4801
-
-
Lee-Hoeflich, S.T.1
Causing, C.G.2
Podkowa, M.3
Zhao, X.4
Wrana, J.L.5
Attisano, L.6
-
39
-
-
0348014691
-
Ecsit-ement on the crossroads of Toll and BMP signal transduction
-
Moustakas A Heldin CH (2003) Ecsit-ement on the crossroads of Toll and BMP signal transduction. Genes Dev 17, 2855 2859.
-
(2003)
Genes Dev
, vol.17
, pp. 2855-2859
-
-
Moustakas, A.1
Heldin, C.H.2
-
40
-
-
0027189976
-
The interplay between multiple enhancer and silencer elements defines the pattern of decapentaplegic expression
-
Huang JD, Schwyter DH, Shirokawa JM Courey AJ (1993) The interplay between multiple enhancer and silencer elements defines the pattern of decapentaplegic expression. Genes Dev 7, 694 704.
-
(1993)
Genes Dev
, vol.7
, pp. 694-704
-
-
Huang, J.D.1
Schwyter, D.H.2
Shirokawa, J.M.3
Courey, A.J.4
-
41
-
-
0029952226
-
Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse
-
Vodovotz Y, Geiser AG, Chesler L, Letterio JJ, Campbell A, Lucia MS, Sporn MB Roberts AB (1996) Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse. J Exp Med 183, 2337 2342.
-
(1996)
J Exp Med
, vol.183
, pp. 2337-2342
-
-
Vodovotz, Y.1
Geiser, A.G.2
Chesler, L.3
Letterio, J.J.4
Campbell, A.5
Lucia, M.S.6
Sporn, M.B.7
Roberts, A.B.8
-
42
-
-
0034680145
-
Toll-like receptors in the induction of the innate immune response
-
Aderem A Ulevitch RJ (2000) Toll-like receptors in the induction of the innate immune response. Nature 406, 782 787.
-
(2000)
Nature
, vol.406
, pp. 782-787
-
-
Aderem, A.1
Ulevitch, R.J.2
-
43
-
-
10744224961
-
Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis
-
Xiao C, Shim JH, Kluppel M, Zhang SS, Dong C, Flavell RA, Fu XY, Wrana JL, Hogan BL Ghosh S (2003) Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. Genes Dev 17, 2933 2949.
-
(2003)
Genes Dev
, vol.17
, pp. 2933-2949
-
-
Xiao, C.1
Shim, J.H.2
Kluppel, M.3
Zhang, S.S.4
Dong, C.5
Flavell, R.A.6
Fu, X.Y.7
Wrana, J.L.8
Hogan, B.L.9
Ghosh, S.10
-
44
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordon-Cardo C, Guise TA Massague J (2003) A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3, 537 549.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordon-Cardo, C.6
Guise, T.A.7
Massague, J.8
|