BMP7/ActRIIB regulates estrogen-dependent apoptosis: New biomarkers for environmental estrogens

Journal of Biochemical and Molecular Toxicology

Volumn 18, Issue 1, 2004, Pages 1-11

  Kusumegi, Takahiro ^a,b   Tanaka, Junko ^a   Kawano, Michihiro ^a   Yonemoto, Junzo ^a,b   Tohyama, Chiharu ^a,b   Sone, Hideko ^a,b,c  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Environmental estrogen; Estradiol; Gene regulation; Steroid hormone

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ACTIVIN RECEPTOR 2; ANTIESTROGEN; BIOLOGICAL MARKER; DNA FRAGMENT; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; LIGAND; MESSENGER RNA; OSTEOGENIC PROTEIN 1; RECEPTOR ANTIBODY; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL STRAIN MCF 7; CHROMATIN; CONTROLLED STUDY; DIESTRUS; DOWN REGULATION; ENDOMETRIUM CELL; ENVIRONMENTAL FACTOR; EPITHELIUM CELL; FEMALE; FEMALE GENITAL SYSTEM; HORMONE INHIBITION; HORMONE RESPONSE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARIECTOMY; PROESTRUS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UTERUS;

ACTIVIN RECEPTORS, TYPE II; AIR POLLUTANTS, OCCUPATIONAL; ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; BONE MORPHOGENETIC PROTEINS; CELL LINE, TUMOR; CHROMATIN; DOWN-REGULATION; EPITHELIAL CELLS; ESTRADIOL; ESTROGENS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HAZARDOUS SUBSTANCES; HUMANS; MICE; OVARIECTOMY; PROMOTER REGIONS (GENETICS); PROTEINS; RECEPTORS, ESTROGEN; RNA, MESSENGER; SIGNAL TRANSDUCTION; UTERUS;

MINK CELL FOCUS-FORMING VIRUS;

EID: 1542360679     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbt.20004     Document Type: Article

References (34)

1. Harvey PW, Johnson I. Approaches to the assessment of toxicity data with endpoints related to endocrine disruption. J Appl Toxicol 2002;22:241-247.
2. Markey CM, Michaelson CL, Veson EC, Sonnenschein C, Soto AM. The mouse uterotrophic assay: A reevaluation of its validity in assessing the estrogenicity of bisphenol A. Environ Health Perspect 2001;109:55-60.
3. Kuang WW, Thompson DA, Hoch RV, Weigel RJ. Differential screening and suppression subtractive hybridization identified genes differentially expressed in an estrogen receptor-positive breast carcinoma cell line. Nucleic Acids Res 1998;26:1116-1123.
4. Ghosh MG, Thompson DA, Weigel RJ. PDZK1 and GREB1 are estrogen-regulated genes expressed in hormone-responsive breast cancer. Cancer Res 2000;60:6367-6375.
5. Inadera H, Hashimoto S, Dong HY, Suzuki T, Nagai S, Yamashita T, Toyoda N, Matsushima K. WISP-2 as a novel estrogen-responsive gene in human breast cancer cells. Biochem Biophys Res Commun 2000;275:108-114.
6. Gould AP, Brockman JJ, Strutt DI, White RA. Targets of homeotic gene control in Drosophila. Nature 1990;348:308-312.
7. Bigler J, Eisenman RN. Isolation of a thyroid hormone-responsive gene by immunoprecipitation of thyroid hormone receptor-DNA complexes. Mol Cell Biol 1994;14:7621-7632.
8. Agarwal S, Avni O, Rao A. Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo. Immunity 2000;12:643-652.
9. Ikeda K, Orimo A, Higashi Y, Muramatsu M, Inoue S. Efp as a primary estrogen-responsive gene in human breast cancer. FEBS Lett 2000;472:9-13.
10. von Bubnoff A, Cho KW. Intracellular BMP signaling regulation in vertebrates: Pathway or network? Dev Biol 2001;239:1-14.
11. Yamashita H, Miyazono K. Bone morphogenetic protein (BMP) receptors and signal transduction. Nippon Rinsho 1999;57:220-226.
12. Massagué, J. TGF-beta signal transduction. Annu Rev Biochem 1998;67:753-791.
13. Attisano L, Wrana JL, Montalvo E, Massagué J. Activation of signalling by the activin receptor complex. Mol Cell Biol 1996;16:1066-1073.
14. Lebrun JJ, Vale WW. Activin and inhibin have antagonistic effects on ligand-dependent heteromerization of the type I and type II activin receptors and human erythroid differentiation. Mol Cell Biol 1997;17:1682-1691.
15. Aloi JA, Marshall JC, Yasin M, Gilrain JT, Haisenleder DJ, Dalkin AC. Ovarian activin receptor subtype and follistatin gene expression in rats: Reciprocal regulation by gonadotropins. Biol Reprod 1997;56:1565-1569.
16. Jia G, Tohyama C, Sone H. DNA damage triggers imbalance of proliferation and apoptosis during development of preneoplastic foci in the liver of Long-Evans Cinnamon rats. Int J Oncol 2002;21:755-761.
17. Jana NR, Sarkar S, Ishizuka M, Yonemoto J, Tohyama C, Sone H. Role of estradiol receptor-alpha in differential expression of 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible genes in the RL95-2 and KLE human endometrial cancer cell lines. Arch Biochem Biophys 1999;368:31-39.
18. Cavailles V, Augereau P, Rochefort H. Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cells. Proc Natl Acad Sci USA 1993;90:203-207.
19. Di Simone N, Schneyer AL, Caliandro D, Castellani R, Caruso A. Regulation of endometrial adenocarcinoma cell proliferation by Activin-A and its modulation by 17beta-estradiol. Mol Cell Endocrinol 2002;192:187-195.
20. Monroe DG, Jin DF, Sanders MM. Estrogen opposes the apoptotic effects of bone morphogenetic protein 7 on tissue remodeling. Mol Cell Biol 2000;20:4626-4634.
21. Ozkaynak E, Jin DF, Jelic M, Vakicevic S, Oppermann H. Osteogenic protein-1 mRNA in the uterine endometrium. Biochem Biophys Res Commun 1997;234:242-246.
22. Klein-Hitpass L, Schorpp M, Wagner U, Ryffel GU. An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells. Cell 1986;46:1053-1061.
23. Porter W, Saville B, Hoivik D, Safe S. Functional synergy between the transcription factor Sp1 and the estrogen receptor. Mol Endocrinol 1997;11:1569-1580.
24. Vyhlidal C, Samudio I, Kladde MP, Safe S. Transcriptional activation of transforming growth factor alpha by estradiol: Requirement for both a GC-rich site and an estrogen response element half-site. J Mol Endocrinol 2000;24:329-338.
25. Kato S, Sasaki H, Suzawa M, Masushige S, Tora L, Chambon P, Gronemeyer H. Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors. Mol Cell Biol 1995;15:5858-5867.
26. Furuta Y, Piston DW, Hogan BL. Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. Development 1997;124:2203-2212.
27. Ying Y, Zhao GQ. Detection of multiple bone morphogenetic protein messenger ribonucleic acids and their signal transducer, Smad1, during mouse decidualization. Biol Reprod 2000;63:1781-1786.
28. Rodriguez-Leon J, Merino R, Macias D, Ganan Y, Santesteban E, Hurle JM. Retinoic acid regulates programmed cell death through BMP signalling. Nat Cell Biol 1999;1:125-126.
29. Jiang R, Lan Y, Chapman HD, Shawber C, Norton CR, Serreze DV, Weinmaster G, Gridley T. Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. Genes Dev 1998;12:1046-1057.
30. Mendoza-Rodriguez CA, Merchant-Larios H, Segura-Valdez Md Mde L, Moreno-Mendoza N, Cruz ME, Arteaga-Lopez P, Camacho-Arroyo I, Dominguez R, Cerbon M. Expression of p53 in luminal and glandular epithelium during the growth and regression of rat uterus during the estrous cycle. Mol Reprod Dev 2002;61:445-452.
31. Lai MD, Lee LR, Cheng KS, Wing LY. Expression of pro-liferating cell nuclear antigen in luminal epithelium during the growth and regression of rat uterus. J Endocrinol 2000;166:87-93.
32. Yoon K, Pellaroni L, Ramamoorthy K, Gaido K, Safe S. Ligand structure-dependent differences in activation of estrogen receptor alpha in human HepG2 liver and U2 osteogenic cancer cell lines. Mol Cell Endocrinol 2000;162:211-220.
33. Hiroi H, Tsutsumi O, Momoeda M, Takai Y, Osuga Y, Taketani Y. Differential interactions of bisphenol A and 17beta-estradiol with estrogen receptor alpha (ERalpha) and ERbeta. Endocr J 1999;46:773-778.
34. Ethier JF, Findlay JK. Roles of activin and its signal transduction mechanisms in reproductive tissues. Reproduction 2001;121:667-675.