-
1
-
-
0034976149
-
TGF-β induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation
-
Bonni, S., Wang, H.R., Causing, C.G., Kavsak, P., Stroschein, S.L., Luo, K., and Wrana, J.L. (2001). TGF-β induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation. Nat. Cell Biol. 3, 587-595.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 587-595
-
-
Bonni, S.1
Wang, H.R.2
Causing, C.G.3
Kavsak, P.4
Stroschein, S.L.5
Luo, K.6
Wrana, J.L.7
-
2
-
-
0026342562
-
Molecular nature of Spemann's organizer: The role of the Xenopus homeobox gene goosecoid
-
Cho, K.W., Blumberg, B., Steinbeisser, H., and De Robertis, E.M. (1991). Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell 67, 1111-1120.
-
(1991)
Cell
, vol.67
, pp. 1111-1120
-
-
Cho, K.W.1
Blumberg, B.2
Steinbeisser, H.3
De Robertis, E.M.4
-
3
-
-
0034994419
-
Müllerian inhibiting substance signaling uses a bone morphogenetic protein (BMP)-like pathway mediated by ALK2 and induces SMAD6 expression
-
Clarke, T.R., Hoshiya, Y., Yi, S.E., Liu, X., Lyons, K.M., and Donahoe, P.K. (2001). Müllerian inhibiting substance signaling uses a bone morphogenetic protein (BMP)-like pathway mediated by ALK2 and induces SMAD6 expression. Mol. Endocrinol. 15, 946-599.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 946-599
-
-
Clarke, T.R.1
Hoshiya, Y.2
Yi, S.E.3
Liu, X.4
Lyons, K.M.5
Donahoe, P.K.6
-
4
-
-
0035918274
-
Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation
-
Ebisawa, T., Fukuchi, M., Murakami, G., Chiba, T., Tanaka, K., Imamura, T., and Miyazono, K. (2001). Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation. J. Biol. Chem. 276, 12477-12480.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12477-12480
-
-
Ebisawa, T.1
Fukuchi, M.2
Murakami, G.3
Chiba, T.4
Tanaka, K.5
Imamura, T.6
Miyazono, K.7
-
5
-
-
0034767430
-
Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins
-
Fukuchi, M., Imamura, T., Chiba, T., Ebisawa, T., Kawabata, M., Tanaka, K., and Miyazono, K. (2001). Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins. Mol. Biol. Cell 12, 1431-1443.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1431-1443
-
-
Fukuchi, M.1
Imamura, T.2
Chiba, T.3
Ebisawa, T.4
Kawabata, M.5
Tanaka, K.6
Miyazono, K.7
-
6
-
-
0034623238
-
Engagement of bone morphogenetic protein type IB receptor and Smad1 signaling by anti-Müllerian hormone and its type II receptor
-
Gouedard, L., Chen, Y.G., Thevenet, L., Racine, C., Borie, S., Lamarre, I., Josso, N., Massagué, J., and di Clemente, N. (2000). Engagement of bone morphogenetic protein type IB receptor and Smad1 signaling by anti-Müllerian hormone and its type II receptor. J. Biol. Chem. 275, 27973-27978.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27973-27978
-
-
Gouedard, L.1
Chen, Y.G.2
Thevenet, L.3
Racine, C.4
Borie, S.5
Lamarre, I.6
Josso, N.7
Massagué, J.8
Di Clemente, N.9
-
7
-
-
0035842885
-
The N domain of Smad7 is essential for specific inhibition of transforming growth factor-β signaling
-
Hanyu, A., Ishidou, Y., Ebisawa, T., Shimanuki, T., Imamura, T., and Miyazono, K. (2001). The N domain of Smad7 is essential for specific inhibition of transforming growth factor-β signaling. J. Cell Biol. 155, 1017-1027.
-
(2001)
J. Cell Biol.
, vol.155
, pp. 1017-1027
-
-
Hanyu, A.1
Ishidou, Y.2
Ebisawa, T.3
Shimanuki, T.4
Imamura, T.5
Miyazono, K.6
-
8
-
-
0031964859
-
Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
-
Hata, A., Lagna, G., Massagué, J., and Hemmati-Brivanlou, A. (1998). Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor. Genes Dev. 12, 186-197.
-
(1998)
Genes Dev.
, vol.12
, pp. 186-197
-
-
Hata, A.1
Lagna, G.2
Massagué, J.3
Hemmati-Brivanlou, A.4
-
9
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through SMAD proteins
-
Heldin, C.-H., Miyazono, K., and ten Dijke, P. (1997). TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.-H.1
Miyazono, K.2
Ten Dijke, P.3
-
11
-
-
0029737070
-
Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
-
Hogan, B.L. (1996). Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev. 10, 1580-1594.
-
(1996)
Genes Dev.
, vol.10
, pp. 1580-1594
-
-
Hogan, B.L.1
-
12
-
-
0030765945
-
Smad6 inhibits signalling by the TGF-β superfamily
-
Imamura, T., Takase, M., Nishihara, A., Oeda, E., Hanai, J., Kawabata, M., and Miyazono, K. (1997). Smad6 inhibits signalling by the TGF-β superfamily. Nature 389, 622-62.
-
(1997)
Nature
, vol.389
, pp. 622-662
-
-
Imamura, T.1
Takase, M.2
Nishihara, A.3
Oeda, E.4
Hanai, J.5
Kawabata, M.6
Miyazono, K.7
-
13
-
-
0034093738
-
Smad6 is a Smad1/5-induced Smad inhibitor: Characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter
-
Ishida, W., Hamamoto, K., Kusanagi, K., Yagi, K., Kawabata, M., Takehara, K., Sampath, T.K., Kato, M., and Miyazono, K. (2000). Smad6 is a Smad1/5-induced Smad inhibitor: characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter. J. Biol. Chem. 275, 6075-6079.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6075-6079
-
-
Ishida, W.1
Hamamoto, K.2
Kusanagi, K.3
Yagi, K.4
Kawabata, M.5
Takehara, K.6
Sampath, T.K.7
Kato, M.8
Miyazono, K.9
-
14
-
-
0032029606
-
Signal transduction by bone morphogenetic proteins
-
Kawabata, M., Imamura, T., and Miyazono, K. (1998a). Signal transduction by bone morphogenetic proteins. Cytokine Growth Factor Rev. 9, 49-61.
-
(1998)
Cytokine Growth Factor Rev.
, vol.9
, pp. 49-61
-
-
Kawabata, M.1
Imamura, T.2
Miyazono, K.3
-
15
-
-
0032528041
-
Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors
-
Kawabata, M., Inoue, H., Hanyu, A., Imamura, T., and Miyazono, K. (1998b). Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors. EMBO J. 17, 4056-4065.
-
(1998)
EMBO J.
, vol.17
, pp. 4056-4065
-
-
Kawabata, M.1
Inoue, H.2
Hanyu, A.3
Imamura, T.4
Miyazono, K.5
-
16
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-β receptor for degradation
-
Kavsak, P., Rasmussen, R.K., Causing, C.G., Bonni, S., Zhu, H., Thomsen, G.H., and Wrana, J.L. (2000). Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-β receptor for degradation. Mol. Cell 6, 1365-1375.
-
(2000)
Mol. Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
Wrana, J.L.7
-
17
-
-
0034711290
-
Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-β signaling
-
Lin, X., Liang, M., and Feng, X.H. (2001). Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-β signaling. J. Biol. Chem. 275, 36818-36822.
-
(2001)
J. Biol. Chem.
, vol.275
, pp. 36818-36822
-
-
Lin, X.1
Liang, M.2
Feng, X.H.3
-
18
-
-
0032475884
-
Specific activation of Smad1 signaling pathways by the BMP7 type I receptor
-
Macías-Silva, M., Hoodless, P.A., Tang, S.J., Buchwald, M., and Wrana, J.L. (1998). Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. J. Biol. Chem. 273, 25628-25636.
-
(1998)
ALK2. J. Biol. Chem.
, vol.273
, pp. 25628-25636
-
-
Macías-Silva, M.1
Hoodless, P.A.2
Tang, S.J.3
Buchwald, M.4
Wrana, J.L.5
-
19
-
-
0035032914
-
Divergence and convergence of TGF-β/BMP signaling
-
Miyazono, K., Kusanagi, K., and Inoue, H. (2001). Divergence and convergence of TGF-β/BMP signaling. J. Cell. Physiol. 187, 265-276.
-
(2001)
J. Cell. Physiol.
, vol.187
, pp. 265-276
-
-
Miyazono, K.1
Kusanagi, K.2
Inoue, H.3
-
20
-
-
0030611757
-
Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signalling
-
Nakao, A., et al. (1997). Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signalling. Nature 389, 631-635.
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
-
21
-
-
0031939483
-
Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning
-
Nakayama, T., Snyder, M.A., Grewal, S.S., Tsuneizumi, K., Tabata, T., and Christian, J.L. (1998). Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning. Development 125, 857-867.
-
(1998)
Development
, vol.125
, pp. 857-867
-
-
Nakayama, T.1
Snyder, M.A.2
Grewal, S.S.3
Tsuneizumi, K.4
Tabata, T.5
Christian, J.L.6
-
22
-
-
0035489160
-
The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis
-
Podos, S.D., Hanson, K.K., Wang, Y.C., and Ferguson, E.L. (2001). The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis. Dev. Cell 1, 567-578.
-
(2001)
Dev. Cell
, vol.1
, pp. 567-578
-
-
Podos, S.D.1
Hanson, K.K.2
Wang, Y.C.3
Ferguson, E.L.4
-
23
-
-
0028097108
-
Bone and cartilage differentiation
-
Reddi, A.H. (1994). Bone and cartilage differentiation. Curr. Opin. Genet. Dev. 4, 737-744.
-
(1994)
Curr. Opin. Genet. Dev.
, vol.4
, pp. 737-744
-
-
Reddi, A.H.1
-
24
-
-
0032489280
-
Induction of Smad6 mRNA by bone morphogenetic proteins
-
Takase, M., Imamura, T., Sampath, T.K., Takeda, K., Ichijo, H., Miyazono, K., and Kawabata, M. (1998). Induction of Smad6 mRNA by bone morphogenetic proteins. Biochem. Biophys. Res. Commun. 244, 26-29.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.244
, pp. 26-29
-
-
Takase, M.1
Imamura, T.2
Sampath, T.K.3
Takeda, K.4
Ichijo, H.5
Miyazono, K.6
Kawabata, M.7
-
25
-
-
0028332818
-
Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4
-
ten Dijke, P., Yamashita, H., Sampath, T.K., Reddi, A.H., Estevez, M., Riddle, D.L., Ichijo, H., Heldin, C.-H., and Miyazono, K. (1994). Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. J. Biol. Chem. 269, 16985-16988.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16985-16988
-
-
Ten Dijke, P.1
Yamashita, H.2
Sampath, T.K.3
Reddi, A.H.4
Estevez, M.5
Riddle, D.L.6
Ichijo, H.7
Heldin, C.-H.8
Miyazono, K.9
-
26
-
-
0030863365
-
Daughters against dpp modulates dpp organizing activity in Drosophila wing development
-
Tsuneizumi, K., Nakayama, T., Kamoshida, Y., Kornberg, T.B., Christian, J.L., and Tabata, T. (1997). Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 389, 627-631.
-
(1997)
Nature
, vol.389
, pp. 627-631
-
-
Tsuneizumi, K.1
Nakayama, T.2
Kamoshida, Y.3
Kornberg, T.B.4
Christian, J.L.5
Tabata, T.6
-
27
-
-
0034982133
-
The serine/threonine transmembrane receptor ALK2 mediates Müllerian inhibiting substance signaling
-
Visser, J.A., Olaso, R., Verhoef-Post, M., Kramer, P., Themmen, A.P., and Ingraham, H.A. (2001). The serine/threonine transmembrane receptor ALK2 mediates Müllerian inhibiting substance signaling. Mol. Endocrinol. 15, 936-945.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 936-945
-
-
Visser, J.A.1
Olaso, R.2
Verhoef-Post, M.3
Kramer, P.4
Themmen, A.P.5
Ingraham, H.A.6
-
28
-
-
0035970096
-
Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase
-
Zhang, Y., Chang, C., Gehling, D.J., Hemmati-Brivanlou, A., and Derynck, R. (2001). Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. Proc. Natl. Acad. Sci. USA 98, 974-979.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 974-979
-
-
Zhang, Y.1
Chang, C.2
Gehling, D.J.3
Hemmati-Brivanlou, A.4
Derynck, R.5
-
29
-
-
0033549789
-
A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation
-
Zhu, H., Kavsak, P., Abdollah, S., Wrana, J.L., and Thomsen, G.H. (1999). A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. Nature 400, 687-693.
-
(1999)
Nature
, vol.400
, pp. 687-693
-
-
Zhu, H.1
Kavsak, P.2
Abdollah, S.3
Wrana, J.L.4
Thomsen, G.H.5
|