Regulation and mode of action of the second small RNA activator of RpoS translation, RprA

Molecular Microbiology

Volumn 46, Issue 3, 2002, Pages 813-826

  Majdalani, Nadim ^a   Hernandez, David ^a,b   Gottesman, Susan ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NONE   (Puerto Rico)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL RNA; DOUBLE STRANDED RNA; MESSENGER RNA; RPOS REGULATORY RNA A; SIGMA FACTOR; SIGMA FACTOR RPOS; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; GENE ACTIVATION; GENE CONTROL; GENE INTERACTION; GENE MUTATION; GENE STRUCTURE; GENE TARGETING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RNA TRANSLATION; SYNTHESIS;

BACTERIAL PROTEINS; BASE SEQUENCE; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN BIOSYNTHESIS; RNA, BACTERIAL; RNA, UNTRANSLATED; SEQUENCE ANALYSIS, DNA; SIGMA FACTOR; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0036437019     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2002.03203.x     Document Type: Article

References (44)

1. Altschul, S.F., Gish, W., Miller, W., Myers, E.W., and Lipman, D. (1990) A basic local alignment search tool. J Mol Biol 215: 403-410.
2. Argaman, L., Hershberg, R., Vogel, J., Bejerano, G., Wagner, E.G.H., Margalit, H., and Altuvia, S. (2001) Novel small RNA-encoding genes in the intergenic region of Escherichia coli. Current Biol 11: 941-950.
3. Brill, J.A., Quinlan-Walshe, C., and Gottesman, S. (1988) Fine-structure mapping and identification of two regulators of capsule synthesis in Escherichia coli K-12. J Bacteriol 170: 2599-2611.
4. Brown, L., and Elliott, T. (1996) Efficient translation of the RpoS sigma factor in Salmonella typhimurium requires Host Factor I, an RNA-binding protein encoded by thehfq gene. J Bacteriol 178: 3763-3770.
5. Brown, L., and Elliott, T. (1997) Mutations that increase expression of the rpoS gene and decrease its dependence on hfq function in Salmonella typhimurium. J Bacteriol 179: 656-662.
6. Carballes, F., Bertrand, C., Bouche, J.P., and Cam, K. (1999) Regulation ofEscherichia coli cell division genes ftsA and ftsZ by the two-component system rcsC-rcsB. Mol Microbiol 34: 442-450.
7. Chen, M.H., Takeda, S., Yamada, H., Ishii, Y., Yamashino, T., and Mizuno, T. (2001) Characterization of the RcsC→YojN→RcsB phosphorelay signaling pathway involved in capsular synthesis in Escherichia coli. Biosci Biotechnol Biochem 65: 2364-2367.
8. Chung, C.T., Niemela, S.L., and Miller, R.H. (1989) One-step preparation of competent Escherichia coli: Transformation and storage of bacterial cells in the same solution. Proc Natl Acad Sci USA 86: 2172-2175.
9. Clarke, D.J., Holland, I.B., and Jacq, A. (1997) Point mutations in the transmembrane domain of DjlA, a membrane-linked DnaJ-like protein, abolish its function in promoting colanic acid production via the Rcs signal transduction pathway. Mol Microbiol 25: 933-944.
10. Conter, A.S., Turmy, R., Gutierrez, C., and Cam, K. (2002) The RcsCB His-Asp phosphorelay system is essential to overcome chlorpromazine-induced stress in Escherichia coli. J Bacteriol 184: 2850-2853.
11. Davalos-Garcia, M., Conter, A., Toesca, I., Gutierrez, C., and Cam, K. (2001) Regulation of osmC gene expression by the two-component system rcsB-rcsC in Escherichia coli. J Bacteriol 183: 5870-5876.
12. Ebel, W., Vaughn, G.J., Peters, H.K.I., and Trempy, J.E. (1997) Inactivation ofmdoH leads to increased expression of colanic acid capsular polysaccharide in Escherichia coli. J Bacteriol 179: 6858-6861.
13. Genevaux, P., Wawrzynow, A., Zylicz, M., Georgopoulos, C., and Kelley, W.L. (2001) DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction. J Biol Chem 276: 7906-7912.
14. Gervais, F.G., and Drapeau, G.R. (1992) Identification, cloning, and characterization of rcsF, a new regulator gene for exopolysaccharide synthesis that suppresses the division mutation ftsZ84 in Escherichia coli K-12. J Bacteriol 174: 8016-8022.
15. Gervais, F.G., Phoenix, P., and Drapeau, G.R. (1992) The rcsB gene, a positive regulator of colanic acid biosynthesis in Escherichia coli, is also an activator of ftsZ expression. J Bacteriol 174: 3964-3971.
16. Gottesman, S. (1995) Regulation of capsule synthesis: Modification of the two component paradigm by an accessory unstable regulator. In Two-Component Signal Transduction. Hoch, J.A. and Silhavy, T.J. (eds). Washington, DC: American Society for Microbiology, pp. 253-262.
17. Gottesman, S., and Stout, V. (1991) Regulation of capsular polysaccharide synthesis in Escherichia coli K12. Mol Microbiol 5: 1599-1606.
18. BAD promoter. J Bacteriol 177: 4121-4130.
19. Hengge-Aronis, R. (2000) The general stress response in Escherichia coli. In Bacterial Stress Responses. Storz, G. and Hengge-Aronis, R. (eds). Washington: D.C. American Society for Microbiology Press, pp. 161-178.
20. Kelley, W.L., and Georgopoulos, C. (1997) Positive control of the two-component RcsC/B signal transduction network by DjlA: A member of the DnaJ family of molecular chaperones in Escherichia coli. Mol Microbiol 25: 913-931.
21. Kelm, O., Kiecker, C., Geider, K., and Bernhard, F. (1997) Interaction of the regulator proteins RcsA and RcsB with the promoter of the operon for amylovoran biosynthesis in Erwinia amylovora. Mol Gen Genet 256: 72-83.
22. Lease, R.A., and Belfort, M. (2000) A transacting RNA as a control switch in Escherichia coli: DsrA modulates function by forming alternative structures. Proc Natl Acad Sci USA 97: 9919-9924.
23. Lease, R.A., Cusick, M., and Belfort, M. (1998) Riboregulation in Escherichia coli: DsrA RNA acts by RNA: RNA interactions at multiple loci. Proc Natl Acad Sci USA 95: 12456-12461.
24. Majdalani, N., Cunning, C., Sledjeski, D., Elliott, T., and Gottesman, S. (1998) DsrA RNA regulates translation of RpoS message by an anti-antisense mechanism, independent of its action as an antisilencer of transcription. Proc Natl Acad Sci USA 95: 12462-12467.
25. Majdalani, N., Chen, S., Murrow, J., St. John, K., and Gottesman, S. (2001) Regulation of RpoS by a novel small RNA: The characterization of RprA. Mol Microbiol 39: 1382-1394.
26. Moller, T., Franch, T., Hojrup, P., Keene, D.R., Bachinger, H.P., Brennan, R., and Valentin-Hansen, P. (2002) Hfq: A bacterial Sm-like protein that mediates RNA-RNA interaction. Molec Cell 9: 23-30.
27. Parker, C.T., Kloser, A.W., Schnaitman, C.A., Stein, M.A., Gottesman, S., and Gibson, B.W. (1992) Role of therfaG and rfaP genes in determining the lipopolysaccharide core structure and cell surface properties of Escherichia coli K-12. J Bacteriol 174: 2525-2538.
28. Powell, B.S., Rivas, M.P., Court, D.L., Nakamura, Y., Rivas, M.P., and Turnbough, C.L.J. (1994) Rapid confirmation of single copy lambda prophage integration by PCR. Nucleic Acids Res 22: 5765-5766.
29. Repoila, F., and Gottesman, S. (2001) Signal transduction cascade for regulation of RpoS: Temperature regulation of DsrA. J Bacteriol 183: 4012-4023.
30. Simons, R.W., Houman, F., and Kleckner, N. (1987) Improved single and multicopy lac-based cloning vectors for protein and operon fusions. Gene 53: 85-96.
31. Sledjeski, D.D., and Gottesman, S. (1996) Osmotic shock induction of capsule synthesis in Escherichia coli K-12. J Bacteriol 178: 1204-1206.
32. Sledjeski, D.D., Gupta, A., and Gottesman, S. (1996) The small RNA, DsrA, is essential for the low temperature expression of RpoS during exponential growth in Escherichia coli. EMBO J 15: 3993-4000.
33. Sledjeski, D.D., Whitman, C., and Zhang, A. (2001) Hfq is necessary for regulation by the untranslated RNA DsrA. J Bacteriol 183: 1997-2005.
34. Stout, V., and Gottesman, S. (1991) Regulation of capsular polysaccharide synthesis in Escherichia coli K12. Mol Microbiol 5: 1599-1606.
35. Takeda, S., Fujisawa, Y., Matsubara, M., Aiba, H., and Mizuno, T. (2001) A novel feature of the multistep phosphorelay in Escherichia coli: A revised model of the RcsC→YojN→RcsB signalling pathway implicated in capsular synthesis and swarming behavior. Mol Microbiol 40: 440-450.
36. Torres-Cabassa, A.S., and Gottesman, S. (1987) Capsule synthesis in Escherichia coli K-12 is regulated by proteolysis. J Bacteriol 169: 981-989.
37. Tsui, H.-C.T., Leung, H.-C.E., and Winkler, M.E. (1994) Characterization of broadly pleiotropic phenotypes caused by an hfq insertion mutation in Escherichia coli K-12. Mol Microbiol 13: 35-49.
38. Ulbrandt, N.D., Newitt, J.A., and Bernstein, H.D. (1997) The E. coli signal recognition particle is required for the insertion of a subset of inner membrane proteins. Cell 88: 187-196.
39. Wassarman, K.M. (2002) Small RNAs in bacteria: Diverse regulators of gene expression in response to environmental changes. Cell 109: 141-144.
40. Wassarman, K.M., Repoila, F., Rosenow, C., Storz, G., and Gottesman, S. (2001) Identification of novel small RNAs using comparative genomics and microarrays. Genes Dev 15: 1637-1651.
41. Wehland, M., and Bernhard, F. (2000) The RcsAB box. J Biol Chem 275: 7013-7020.
42. Wehland, M., Kiecker, C., Coplin, D.L., Kelm, O., Saenger, W., and Bernhard, F. (1999) Identification of an RcsA/RcsB recognition motif in the promoters of expopolysaccharide biosynthetic operons from Erwinia amylovora and Pantoea stewartii subspecies Stewartii. J Biol Chem 274: 3300-3307.
43. Yu, D.G., Ellis, H.M., Lee, E.C., Jenkins, N.A., Copeland, N.G., and Court, D.L. (2000) An efficient recombination system for chromosome engineering in Escherichia coli. Proc Natl Acad Sci USA 97: 5978-5983.
44. Zhang, A., Wassarman, K.M., Ortega, J., Steven, A.C., and Storz, G. (2002) The Sm-like Hfq protein increases OxyS RNA interaction with target mRNAs. Molec Cell 9: 11-22.