Mistranslation of Membrane Proteins and Two-Component System Activation Trigger Antibiotic-Mediated Cell Death

Cell

Volumn 135, Issue 4, 2008, Pages 679-690

  Kohanski, Michael A ^b,c   Dwyer, Daniel J ^b,d   Wierzbowski, Jamey ^b   Cottarel, Guillaume ^b   Collins, James J ^a,b,c  

^a BOSTON UNIVERSITY   (United States)

^b Center for Advanced Biotechnology   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d USA   (United States)

Author keywords

MICROBIO; SIGNALING

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; GENTAMICIN; HYDROXYL RADICAL; KANAMYCIN; MEMBRANE PROTEIN; SPECTINOMYCIN;

ARTICLE; BACTERICIDAL ACTIVITY; CELL DEATH; CONTROLLED STUDY; DRUG MECHANISM; ESCHERICHIA COLI; NONHUMAN; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 55449126342     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2008.09.038     Document Type: Article

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