메뉴 건너뛰기




Volumn 89, Issue 4, 2010, Pages 331-343

Critical reviews in oral biology & medicine: Osteocytes and WNT: The mechanical control of bone formation

Author keywords

Beta catenin; Bone; Mechanotransduction; Osteocytes; Sclerostin; Sost.; WNT

Indexed keywords

BETA CATENIN; BONE MORPHOGENETIC PROTEIN; WNT PROTEIN;

EID: 77949603251     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034510363963     Document Type: Article
Times cited : (100)

References (238)
  • 1
    • 0032892448 scopus 로고    scopus 로고
    • Site-specific effects of strength training on bone structure and geometry of ultradistal radius in postmenopausal women
    • Adami S., Gatti D., Braga V., Bianchini D., Rossini M. (1999). Site-specific effects of strength training on bone structure and geometry of ultradistal radius in postmenopausal women. J Bone Miner Res 14: 120-124.
    • (1999) J Bone Miner Res , vol.14 , pp. 120-124
    • Adami, S.1    Gatti, D.2    Braga, V.3    Bianchini, D.4    Rossini, M.5
  • 3
    • 0014483772 scopus 로고
    • The time sequence of tissue regeneration in human extraction wounds
    • Amler MH (1969). The time sequence of tissue regeneration in human extraction wounds. Oral Surg Oral Med Oral Pathol 27: 309-318.
    • (1969) Oral Surg Oral Med Oral Pathol , vol.27 , pp. 309-318
    • Amler, M.H.1
  • 5
    • 0036113510 scopus 로고    scopus 로고
    • WNT signals are required for the initiation of hair follicle development
    • Andl T., Reddy ST, Gaddapara T., Millar SE (2002). WNT signals are required for the initiation of hair follicle development. Dev Cell 2: 643-653.
    • (2002) Dev Cell , vol.2 , pp. 643-653
    • Andl, T.1    Reddy, S.T.2    Gaddapara, T.3    Millar, S.E.4
  • 6
    • 67649470380 scopus 로고    scopus 로고
    • Proximal events in Wnt signal transduction
    • Angers S., Moon RT (2009). Proximal events in Wnt signal transduction Nat Rev Mol Cell Biol 10: 468-477.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 468-477
    • Angers, S.1    Moon, R.T.2
  • 7
    • 33845355511 scopus 로고    scopus 로고
    • Diversity of LEF/TCF action in development and disease
    • Arce L., Yokoyama NN, Waterman ML (2006). Diversity of LEF/TCF action in development and disease. Oncogene 25: 7492-7504.
    • (2006) Oncogene , vol.25 , pp. 7492-7504
    • Arce, L.1    Yokoyama, N.N.2    Waterman, M.L.3
  • 8
    • 64849094619 scopus 로고    scopus 로고
    • Jacobs CR (2009). Mechanically induced osteogenic differentiation-the role of RhoA, ROCKII and cytoskeletal dynamics
    • Arnsdorf EJ, Tummala P., Kwon RY, Jacobs CR (2009). Mechanically induced osteogenic differentiation-the role of RhoA, ROCKII and cytoskeletal dynamics. J Cell Sci 122 (Pt 4). 546-553.
    • J Cell Sci , vol.122 , Issue.4 , pp. 546-553
    • Arnsdorf, E.J.1    Tummala, P.2    Kwon, R.Y.3
  • 9
    • 0032529161 scopus 로고    scopus 로고
    • Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
    • Axelrod JD, Miller JR, Shulman JM, Moon RT, Perrimon N. (1998). Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev 12: 2610-2622.
    • (1998) Genes Dev , vol.12 , pp. 2610-2622
    • Axelrod, J.D.1    Miller, J.R.2    Shulman, J.M.3    Moon, R.T.4    Perrimon, N.5
  • 11
    • 55249101949 scopus 로고    scopus 로고
    • The binding between sclerostin and LRP5 is altered by DKK1 and by high-bone mass LRP5 mutations
    • Balemans W., Piters E., Cleiren E., Ai M., Van Wesenbeeck L., Warman ML, et al. (2008). The binding between sclerostin and LRP5 is altered by DKK1 and by high-bone mass LRP5 mutations. Calcif Tissue Int 82: 445-453.
    • (2008) Calcif Tissue Int , vol.82 , pp. 445-453
    • Balemans, W.1    Piters, E.2    Cleiren, E.3    Ai, M.4    Van Wesenbeeck, L.5    Warman, M.L.6
  • 12
    • 34250823973 scopus 로고    scopus 로고
    • Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton
    • Baron R., Rawadi G. (2007). Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton. Endocrinology 148: 2635-2643.
    • (2007) Endocrinology , vol.148 , pp. 2635-2643
    • Baron, R.1    Rawadi, G.2
  • 13
    • 26844521277 scopus 로고    scopus 로고
    • Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: A novel mechanism for hormonal control of osteoblastogenesis
    • Bellido T., Ali AA, Gubrij I., Plotkin LI, Fu Q., OBrien CA, et al. (2005). Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. Endocrinology 146: 4577-4583.
    • (2005) Endocrinology , vol.146 , pp. 4577-4583
    • Bellido, T.1    Ali, A.A.2    Gubrij, I.3    Plotkin, L.I.4    Fu, Q.5    Obrien, C.A.6
  • 14
    • 38749086157 scopus 로고    scopus 로고
    • Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation
    • Bennett CN, Ouyang H., Ma YL, Zeng Q., Gerin I., Sousa KM, et al. (2007). Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation. J Bone Miner Res 22: 1924-1932.
    • (2007) J Bone Miner Res , vol.22 , pp. 1924-1932
    • Bennett, C.N.1    Ouyang, H.2    Ma, Y.L.3    Zeng, Q.4    Gerin, I.5    Sousa, K.M.6
  • 15
    • 0023515309 scopus 로고
    • Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: Potential role of an analog of the retinal protein arrestin (48-kDa protein)
    • Benovic JL, Kuhn H., Weyand I., Codina J., Caron MG, Lefkowitz RJ (1987). Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein). Proc Natl Acad Sci USA 84: 8879-8882.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8879-8882
    • Benovic, J.L.1    Kuhn, H.2    Weyand, I.3    Codina, J.4    Caron, M.G.5    Lefkowitz, R.J.6
  • 16
  • 18
    • 0033817339 scopus 로고    scopus 로고
    • Beta-catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator
    • Billin AN, Thirlwell H., Ayer DE (2000). Beta-catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator. Mol Cell Biol 20: 6882-6890.
    • (2000) Mol Cell Biol , vol.20 , pp. 6882-6890
    • Billin, A.N.1    Thirlwell, H.2    Ayer, D.E.3
  • 19
    • 11144296595 scopus 로고    scopus 로고
    • Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells
    • Boland GM, Perkins G., Hall DJ, Tuan RS (2004). Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells. J Cell Biochem 93: 1210-1230.
    • (2004) J Cell Biochem , vol.93 , pp. 1210-1230
    • Boland, G.M.1    Perkins, G.2    Hall, D.J.3    Tuan, R.S.4
  • 20
    • 34247495109 scopus 로고    scopus 로고
    • Mechanosensation and transduction in osteocytes
    • Bonewald LF (2006). Mechanosensation and transduction in osteocytes. Bonekey Osteovision 3: 7-15.
    • (2006) Bonekey Osteovision , vol.3 , pp. 7-15
    • Bonewald, L.F.1
  • 21
    • 40849106249 scopus 로고    scopus 로고
    • Osteocytes, mechanosensing and Wnt signaling
    • Bonewald LF, Johnson ML (2008). Osteocytes, mechanosensing and Wnt signaling. Bone 42: 606-615.
    • (2008) Bone , vol.42 , pp. 606-615
    • Bonewald, L.F.1    Johnson, M.L.2
  • 22
    • 0032967755 scopus 로고    scopus 로고
    • Dishevelled: At the crossroads of divergent intracellular signaling pathways
    • Boutros M., Mlodzik M. (1999). Dishevelled: at the crossroads of divergent intracellular signaling pathways. Mech Dev 83: 27-37.
    • (1999) Mech Dev , vol.83 , pp. 27-37
    • Boutros, M.1    Mlodzik, M.2
  • 23
    • 0034243850 scopus 로고    scopus 로고
    • Porcine fetal enamel matrix derivative enhances bone formation induced by demineralized freeze dried bone allograft in vivo
    • Boyan BD, Weesner TC, Lohmann CH, Andreacchio D., Carnes DL, Dean DD, et al. (2000). Porcine fetal enamel matrix derivative enhances bone formation induced by demineralized freeze dried bone allograft in vivo. J Periodontol 71: 1278-1286.
    • (2000) J Periodontol , vol.71 , pp. 1278-1286
    • Boyan, B.D.1    Weesner, T.C.2    Lohmann, C.H.3    Andreacchio, D.4    Carnes, D.L.5    Dean, D.D.6
  • 24
    • 0037118285 scopus 로고    scopus 로고
    • High bone density due to a mutation in LDL-receptor-related protein 5
    • Boyden LM, Mao J., Belsky J., Mitzner L., Farhi A., Mitnick MA, et al. (2002). High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med 346: 1513-1521.
    • (2002) N Engl J Med , vol.346 , pp. 1513-1521
    • Boyden, L.M.1    Mao, J.2    Belsky, J.3    Mitzner, L.4    Farhi, A.5    Mitnick, M.A.6
  • 25
    • 67650882778 scopus 로고    scopus 로고
    • A rough surface implant neck with microthreads reduces the amount of marginal bone loss: A prospective clinical study
    • Bratu EA, Tandlich M., Shapira L. (2009). A rough surface implant neck with microthreads reduces the amount of marginal bone loss: a prospective clinical study. Clin Oral Implants Res 20: 827-832 ; erratum in Clin Oral Implants Res 20: 1185, 2009.
    • (2009) Clin Oral Implants Res , vol.20 , pp. 827-832
    • Bratu, E.A.1    Tandlich, M.2    Shapira, L.3
  • 26
    • 67349265175 scopus 로고    scopus 로고
    • The relation of femoral osteon geometry to age, sex, height and weight
    • Britz HM, Thomas CD, Clement JG, Cooper DM (2009). The relation of femoral osteon geometry to age, sex, height and weight. Bone 45: 77-83.
    • (2009) Bone , vol.45 , pp. 77-83
    • Britz, H.M.1    Thomas, C.D.2    Clement, J.G.3    Cooper, D.M.4
  • 27
    • 0141565397 scopus 로고    scopus 로고
    • Strain-derived canalicular fluid flow regulates osteoclast activity in a remodelling osteon-a proposal
    • Burger EH, Klein-Nulend J., Smit TH (2003). Strain-derived canalicular fluid flow regulates osteoclast activity in a remodelling osteon-a proposal. J Biomech 36: 1453-1459.
    • (2003) J Biomech , vol.36 , pp. 1453-1459
    • Burger, E.H.1    Klein-Nulend, J.2    Smit, T.H.3
  • 28
    • 77949616096 scopus 로고    scopus 로고
    • Jiang JX (2009). Connexin 43 hemichannel opening associated with Prostaglandin E(2) release is adaptively regulated by mechanical stimulation
    • Burra S., Jiang JX (2009). Connexin 43 hemichannel opening associated with Prostaglandin E(2) release is adaptively regulated by mechanical stimulation. Commun Integr Biol 2: 239-240.
    • Commun Integr Biol , vol.2 , pp. 239-240
    • Burra, S.1
  • 30
    • 0344410096 scopus 로고    scopus 로고
    • Dynamics of bone tissue formation in tooth extraction sites. An experimental study in dogs
    • Cardaropoli G., Araujo M., Lindhe J. (2003). Dynamics of bone tissue formation in tooth extraction sites. An experimental study in dogs. J Clin Periodontol 30: 809-818.
    • (2003) J Clin Periodontol , vol.30 , pp. 809-818
    • Cardaropoli, G.1    Araujo, M.2    Lindhe, J.3
  • 32
    • 35648990464 scopus 로고    scopus 로고
    • Noncanonical Wnt-4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK
    • Chang J., Sonoyama W., Wang Z., Jin Q., Zhang C., Krebsbach PH, et al. (2007). Noncanonical Wnt-4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK. J Biol Chem 282: 30938-30948.
    • (2007) J Biol Chem , vol.282 , pp. 30938-30948
    • Chang, J.1    Sonoyama, W.2    Wang, Z.3    Jin, Q.4    Zhang, C.5    Krebsbach, P.H.6
  • 33
    • 74349084953 scopus 로고    scopus 로고
    • PDGF-B gene therapy accelerates bone engineering and oral implant osseointegration
    • Chang PC, Seol YJ, Cirelli JA, Pellegrini G., Jin Q., Franco LM, et al. (2009). PDGF-B gene therapy accelerates bone engineering and oral implant osseointegration. Gene Ther 17: 95-104.
    • (2009) Gene Ther , vol.17 , pp. 95-104
    • Chang, P.C.1    Seol, Y.J.2    Cirelli, J.A.3    Pellegrini, G.4    Jin, Q.5    Franco, L.M.6
  • 35
    • 69949186302 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development
    • Chen J., Lan Y., Baek JA, Gao Y., Jiang R. (2009). Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development Dev Biol 334: 174-185.
    • (2009) Dev Biol , vol.334 , pp. 174-185
    • Chen, J.1    Lan, Y.2    Baek, J.A.3    Gao, Y.4    Jiang, R.5
  • 36
    • 21844442343 scopus 로고    scopus 로고
    • Mechanical strain opens connexin 43 hemichannels in osteocytes: A novel mechanism for the release of prostaglandin
    • Cherian PP, Siller-Jackson AJ, Gu S., Wang X., Bonewald LF, Sprague E., et al. (2005). Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin. Mol Biol Cell 16: 3100-3106.
    • (2005) Mol Biol Cell , vol.16 , pp. 3100-3106
    • Cherian, P.P.1    Siller-Jackson, A.J.2    Gu, S.3    Wang, X.4    Bonewald, L.F.5    Sprague, E.6
  • 37
    • 18944388680 scopus 로고    scopus 로고
    • Mouse axin and axin2/conductin proteins are functionally equivalent in vivo
    • Chia IV, Costantini F. (2005). Mouse axin and axin2/conductin proteins are functionally equivalent in vivo. Mol Cell Biol 25: 4371-4376.
    • (2005) Mol Cell Biol , vol.25 , pp. 4371-4376
    • Chia, I.V.1    Costantini, F.2
  • 38
    • 67349101267 scopus 로고    scopus 로고
    • Wnt inhibitory factor (WIF)-1 inhibits osteoblastic differentiation in mouse embryonic mesenchymal cells
    • Cho SW, Yang JY, Sun HJ, Jung JY, Her SJ, Cho HY, et al. (2009). Wnt inhibitory factor (WIF)-1 inhibits osteoblastic differentiation in mouse embryonic mesenchymal cells. Bone 44: 1069-1077.
    • (2009) Bone , vol.44 , pp. 1069-1077
    • Cho, S.W.1    Yang, J.Y.2    Sun, H.J.3    Jung, J.Y.4    Her, S.J.5    Cho, H.Y.6
  • 40
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. (2006). Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 41
    • 44849136948 scopus 로고    scopus 로고
    • Single minimally invasive surgical technique with an enamel matrix derivative to treat multiple adjacent intra-bony defects: Clinical outcomes and patient morbidity
    • Cortellini P., Nieri M., Prato GP, Tonetti MS (2008). Single minimally invasive surgical technique with an enamel matrix derivative to treat multiple adjacent intra-bony defects: clinical outcomes and patient morbidity. J Clin Periodontol 35: 605-613.
    • (2008) J Clin Periodontol , vol.35 , pp. 605-613
    • Cortellini, P.1    Nieri, M.2    Prato, G.P.3    Tonetti, M.S.4
  • 42
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross DA, Alessi DR, Cohen P., Andjelkovich M., Hemmings BA (1995). Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378: 785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 44
    • 0032531880 scopus 로고    scopus 로고
    • Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth
    • Dassule HR, McMahon AP (1998). Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev Biol 202: 215-227.
    • (1998) Dev Biol , vol.202 , pp. 215-227
    • Dassule, H.R.1    McMahon, A.P.2
  • 45
    • 2342642106 scopus 로고    scopus 로고
    • Effects of Wnt signaling on proliferation and differentiation of human mesenchymal stem cells
    • De Boer J., Wang HJ, Van Blitterswijk C. (2004). Effects of Wnt signaling on proliferation and differentiation of human mesenchymal stem cells. Tissue Eng 10: 393-401.
    • (2004) Tissue Eng , vol.10 , pp. 393-401
    • De Boer, J.1    Wang, H.J.2    Van Blitterswijk, C.3
  • 46
    • 28844442933 scopus 로고    scopus 로고
    • Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: A new model to study cortical and cancellous compartments in a single loaded element
    • De Souza RL, Matsuura M., Eckstein F., Rawlinson SC, Lanyon LE, Pitsillides AA (2005). Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: a new model to study cortical and cancellous compartments in a single loaded element. Bone 37: 810-818.
    • (2005) Bone , vol.37 , pp. 810-818
    • De Souza, R.L.1    Matsuura, M.2    Eckstein, F.3    Rawlinson, S.C.4    Lanyon, L.E.5    Pitsillides, A.A.6
  • 47
    • 58049204438 scopus 로고    scopus 로고
    • Potential new drug targets for osteoporosis
    • Deal C. (2009). Potential new drug targets for osteoporosis. Nat Clin Pract Rheumatol 5: 20-27 ; erratum in Nat Clin Pract Rheumatol 5: 174, 2009.
    • (2009) Nat Clin Pract Rheumatol , vol.5 , pp. 20-27
    • Deal, C.1
  • 48
    • 34249311572 scopus 로고    scopus 로고
    • Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines
    • Doble BW, Patel S., Wood GA, Kockeritz LK, Woodgett JR (2007). Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines. Dev Cell 12: 957-971.
    • (2007) Dev Cell , vol.12 , pp. 957-971
    • Doble, B.W.1    Patel, S.2    Wood, G.A.3    Kockeritz, L.K.4    Woodgett, J.R.5
  • 49
    • 18044403181 scopus 로고    scopus 로고
    • The influence of static and dynamic loading on marginal bone reactions around osseointegrated implants: An animal experimental study
    • Duyck J., Ronold HJ, Van Oosterwyck H., Naert I., Vander Sloten J., Ellingsen JE (2001). The influence of static and dynamic loading on marginal bone reactions around osseointegrated implants: an animal experimental study. Clin Oral Implants Res 12: 207-218.
    • (2001) Clin Oral Implants Res , vol.12 , pp. 207-218
    • Duyck, J.1    Ronold, H.J.2    Van Oosterwyck, H.3    Naert, I.4    Vander Sloten, J.5    Ellingsen, J.E.6
  • 50
    • 70349920691 scopus 로고    scopus 로고
    • A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis
    • Eddleston A., Marenzana M., Moore AR, Stephens P., Muzylak M., Marshall D., et al. (2009). A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis. J Bone Miner Res 24: 1662-1671.
    • (2009) J Bone Miner Res , vol.24 , pp. 1662-1671
    • Eddleston, A.1    Marenzana, M.2    Moore, A.R.3    Stephens, P.4    Muzylak, M.5    Marshall, D.6
  • 51
    • 77954863109 scopus 로고    scopus 로고
    • The effect of thread design on stress distribution in a solid screw implant: A 3D finite element analysis
    • Eraslan O., Inan O. (2009). The effect of thread design on stress distribution in a solid screw implant: a 3D finite element analysis. Clin Oral Investig [Epub ahead of print] June 20, 2009 (in press).
    • (2009) Clin Oral Investig
    • Eraslan, O.1    Inan, O.2
  • 54
    • 33750454816 scopus 로고    scopus 로고
    • Loss of DMP1I causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism
    • Feng JQ, Ward LM, Liu S., Lu Y., Xie Y., Yuan B., et al. (2006). Loss of DMP1I causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet 38: 1310-1315.
    • (2006) Nat Genet , vol.38 , pp. 1310-1315
    • Feng, J.Q.1    Ward, L.M.2    Liu, S.3    Lu, Y.4    Xie, Y.5    Yuan, B.6
  • 55
    • 65649100104 scopus 로고    scopus 로고
    • Unique and overlapping functions of GSK-3 isoforms in cell differentiation and proliferation and cardiovascular development
    • Force T., Woodgett JR (2009). Unique and overlapping functions of GSK-3 isoforms in cell differentiation and proliferation and cardiovascular development J Biol Chem 284: 9643-9647.
    • (2009) J Biol Chem , vol.284 , pp. 9643-9647
    • Force, T.1    Woodgett, J.R.2
  • 56
    • 0029998565 scopus 로고    scopus 로고
    • Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo
    • Forwood MR (1996). Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo. J Bone Miner Res 11: 1688-1693.
    • (1996) J Bone Miner Res , vol.11 , pp. 1688-1693
    • Forwood, M.R.1
  • 57
    • 0028800124 scopus 로고
    • Skeletal adaptations to mechanical usage: Results from tibial loading studies in rats
    • Forwood MR, Turner CH (1995). Skeletal adaptations to mechanical usage: results from tibial loading studies in rats. Bone 17 (4 Suppl). 197S - 205S.
    • (1995) Bone , vol.17 , Issue.4
    • Forwood, M.R.1    Turner, C.H.2
  • 58
    • 33644975844 scopus 로고    scopus 로고
    • Buried alive: How osteoblasts become osteocytes
    • Franz-Odendaal TA, Hall BK, Witten PE (2006). Buried alive: how osteoblasts become osteocytes. Dev Dyn 235: 176-190.
    • (2006) Dev Dyn , vol.235 , pp. 176-190
    • Franz-Odendaal, T.A.1    Hall, B.K.2    Witten, P.E.3
  • 59
    • 0034947962 scopus 로고    scopus 로고
    • Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway
    • Furuhashi M., Yagi K., Yamamoto H., Furukawa Y., Shimada S., Nakamura Y., et al. (2001). Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway. Mol Cell Biol 21: 5132-5141.
    • (2001) Mol Cell Biol , vol.21 , pp. 5132-5141
    • Furuhashi, M.1    Yagi, K.2    Yamamoto, H.3    Furukawa, Y.4    Shimada, S.5    Nakamura, Y.6
  • 61
    • 0036008477 scopus 로고    scopus 로고
    • Alveolar bone remodelling pattern of the rat incisor under different functional conditions as shown by minocycline administration
    • Gerlach RF, Toledo DB, Fonseca RB, Novaes PD, Line SR, Merzel J. (2002). Alveolar bone remodelling pattern of the rat incisor under different functional conditions as shown by minocycline administration. Arch Oral Biol 47: 203-209.
    • (2002) Arch Oral Biol , vol.47 , pp. 203-209
    • Gerlach, R.F.1    Toledo, D.B.2    Fonseca, R.B.3    Novaes, P.D.4    Line, S.R.5    Merzel, J.6
  • 62
    • 0031227586 scopus 로고    scopus 로고
    • In vitro studies on periodontal ligament cells and enamel matrix derivative
    • Gestrelius S., Andersson C., Lidstrom D., Hammarstrm L., Somerman M. (1997). In vitro studies on periodontal ligament cells and enamel matrix derivative. J Clin Periodontol 24 (9 Pt 2). 685-692.
    • (1997) J Clin Periodontol , vol.24 , Issue.9 PART 2 , pp. 685-692
    • Gestrelius, S.1    Andersson, C.2    Lidstrom, D.3    Hammarstrm, L.4    Somerman, M.5
  • 64
    • 20244373613 scopus 로고    scopus 로고
    • Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation
    • Glass DA 2nd, Bialek P., Ahn JD, Starbuck M., Patel MS, Clevers H., et al. (2005). Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell 8: 751-764.
    • (2005) Dev Cell , vol.8 , pp. 751-764
    • Bialek, P.1    Ahn, J.D.2    Starbuck, M.3    Patel, M.S.4    Clevers, H.5
  • 65
    • 33644523762 scopus 로고    scopus 로고
    • Wnt signals can function as positional cues in establishing cell polarity
    • Goldstein B., Takeshita H., Mizumoto K., Sawa H. (2006). Wnt signals can function as positional cues in establishing cell polarity. Dev Cell 10: 391-396.
    • (2006) Dev Cell , vol.10 , pp. 391-396
    • Goldstein, B.1    Takeshita, H.2    Mizumoto, K.3    Sawa, H.4
  • 66
    • 18044386744 scopus 로고    scopus 로고
    • LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
    • Gong Y., Slee RB, Fukai N., Rawadi G., Roman-Roman S., Reginato AM, et al. (2001). LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 107: 513-523.
    • (2001) Cell , vol.107 , pp. 513-523
    • Gong, Y.1    Slee, R.B.2    Fukai, N.3    Rawadi, G.4    Roman-Roman, S.5    Reginato, A.M.6
  • 67
    • 0029770657 scopus 로고    scopus 로고
    • Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor
    • Goodman OB Jr, Krupnick JG, Santini F., Gurevich VV, Penn RB, Gagnon AW, et al. (1996). Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature 383: 447-450.
    • (1996) Nature , vol.383 , pp. 447-450
    • Krupnick, J.G.1    Santini, F.2    Gurevich, V.V.3    Penn, R.B.4    Gagnon, A.W.5
  • 68
    • 33747339465 scopus 로고    scopus 로고
    • Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors
    • Gordon MD, Nusse R. (2006). Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem 281: 22429-22433.
    • (2006) J Biol Chem , vol.281 , pp. 22429-22433
    • Gordon, M.D.1    Nusse, R.2
  • 70
    • 0037439138 scopus 로고    scopus 로고
    • Coactivation of Rac and Rho by Wnt/ Frizzled signaling is required for vertebrate gastrulation
    • Habas R., Dawid IB, He X. (2003). Coactivation of Rac and Rho by Wnt/ Frizzled signaling is required for vertebrate gastrulation. Genes Dev 17: 295-309.
    • (2003) Genes Dev , vol.17 , pp. 295-309
    • Habas, R.1    Dawid, I.B.2    He, X.3
  • 71
    • 33745498231 scopus 로고    scopus 로고
    • Bone height measurements around a dental implant after a 6-month space flight: A case report
    • Haignere C., Jonas P., Khayat P., Girot G. (2006). Bone height measurements around a dental implant after a 6-month space flight: a case report. Int J Oral Maxillofac Implants 21: 450-454.
    • (2006) Int J Oral Maxillofac Implants , vol.21 , pp. 450-454
    • Haignere, C.1    Jonas, P.2    Khayat, P.3    Girot, G.4
  • 72
    • 55549113911 scopus 로고    scopus 로고
    • FHL2 mediates dexamethasone-induced mesenchymal cell differentiation into osteoblasts by activating Wnt/beta-catenin signaling-dependent Runx2 expression
    • Hamidouche Z., Hay E., Vaudin P., Charbord P., Schule R., Marie PJ, et al. (2008). FHL2 mediates dexamethasone-induced mesenchymal cell differentiation into osteoblasts by activating Wnt/beta-catenin signaling-dependent Runx2 expression. FASEB J 22: 3813-3822.
    • (2008) FASEB J , vol.22 , pp. 3813-3822
    • Hamidouche, Z.1    Hay, E.2    Vaudin, P.3    Charbord, P.4    Schule, R.5    Marie, P.J.6
  • 73
    • 72449168917 scopus 로고    scopus 로고
    • The effects of exercise and physical activity participation on bone mass and geometry in postmenopausal women: A systematic review of pQCT studies
    • Hamilton CJ, Swan VJ, Jamal SA (2009). The effects of exercise and physical activity participation on bone mass and geometry in postmenopausal women: a systematic review of pQCT studies. Osteoporos Int 21: 11-23.
    • (2009) Osteoporos Int , vol.21 , pp. 11-23
    • Hamilton, C.J.1    Swan, V.J.2    Jamal, S.A.3
  • 74
    • 0031230219 scopus 로고    scopus 로고
    • Periodontal regeneration in a buccal dehiscence model in monkeys after application of enamel matrix proteins
    • Hammarstrm L., Heijl L., Gestrelius S. (1997). Periodontal regeneration in a buccal dehiscence model in monkeys after application of enamel matrix proteins. J Clin Periodontol 24 (9 Pt 2). 669-677.
    • (1997) J Clin Periodontol , vol.24 , Issue.9 PART 2 , pp. 669-677
    • Hammarstrm, L.1    Heijl, L.2    Gestrelius, S.3
  • 75
    • 33644828002 scopus 로고    scopus 로고
    • A Wnt canon orchestrating osteoblastogenesis
    • Hartmann C. (2006). A Wnt canon orchestrating osteoblastogenesis. Trends Cell Biol 16: 151-158.
    • (2006) Trends Cell Biol , vol.16 , pp. 151-158
    • Hartmann, C.1
  • 76
    • 59449095748 scopus 로고    scopus 로고
    • N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/ beta-catenin signaling, osteoblast function, and bone formation
    • Hay E., Laplantine E., Geoffroy V., Frain M., Kohler T., Muller R., et al. (2009). N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/ beta-catenin signaling, osteoblast function, and bone formation. Mol Cell Biol 29: 953-964.
    • (2009) Mol Cell Biol , vol.29 , pp. 953-964
    • Hay, E.1    Laplantine, E.2    Geoffroy, V.3    Frain, M.4    Kohler, T.5    Muller, R.6
  • 77
    • 61849137831 scopus 로고    scopus 로고
    • Inhibiting Dickkopf-1 (Dkk1) removes suppression of bone formation and prevents the development of osteolytic bone disease in multiple myeloma
    • Heath DJ, Chantry AD, Buckle CH, Coulton L., Shaughnessy JD Jr, Evans HR, et al. (2009). Inhibiting Dickkopf-1 (Dkk1) removes suppression of bone formation and prevents the development of osteolytic bone disease in multiple myeloma. J Bone Miner Res 24: 425-436.
    • (2009) J Bone Miner Res , vol.24 , pp. 425-436
    • Heath, D.J.1    Chantry, A.D.2    Buckle, C.H.3    Coulton, L.4    Evans, H.R.5
  • 78
    • 0031227926 scopus 로고    scopus 로고
    • Enamel matrix derivative (EMDOGAIN) in the treatment of intrabony periodontal defects
    • Heijl L., Heden G., Svardstrom G., Ostgren A. (1997). Enamel matrix derivative (EMDOGAIN) in the treatment of intrabony periodontal defects. J Clin Periodontol 24 (9 Pt 2). 705-714.
    • (1997) J Clin Periodontol , vol.24 , Issue.9 PART 2 , pp. 705-714
    • Heijl, L.1    Heden, G.2    Svardstrom, G.3    Ostgren, A.4
  • 79
    • 47749102180 scopus 로고    scopus 로고
    • Differentiation of osteoblasts and osteocytes from mesenchymal stem cells
    • Heino TJ, Hentunen TA (2008). Differentiation of osteoblasts and osteocytes from mesenchymal stem cells. Curr Stem Cell Res Ther 3: 131-145.
    • (2008) Curr Stem Cell Res Ther , vol.3 , pp. 131-145
    • Heino, T.J.1    Hentunen, T.A.2
  • 80
    • 67149133212 scopus 로고    scopus 로고
    • Evidence for the role of osteocytes in the initiation of targeted remodeling
    • Heino TJ, Kurata K., Higaki H., Vaananen HK (2009). Evidence for the role of osteocytes in the initiation of targeted remodeling Technol Health Care 17: 49-56.
    • (2009) Technol Health Care , vol.17 , pp. 49-56
    • Heino, T.J.1    Kurata, K.2    Higaki, H.3    Vaananen, H.K.4
  • 81
    • 34548016053 scopus 로고    scopus 로고
    • Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes
    • Hirao M., Hashimoto J., Yamasaki N., Ando W., Tsuboi H., Myoui A., et al. (2007). Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes. J Bone Miner Metab 25: 266-276.
    • (2007) J Bone Miner Metab , vol.25 , pp. 266-276
    • Hirao, M.1    Hashimoto, J.2    Yamasaki, N.3    Ando, W.4    Tsuboi, H.5    Myoui, A.6
  • 82
    • 0031750465 scopus 로고    scopus 로고
    • Expression pattern of two Frizzled-related genes, Frzb-1 and Sfrp-1, during mouse embryogenesis suggests a role for modulating action of Wnt family members
    • Hoang BH, Thomas JT, Abdul-Karim FW, Correia KM, Conlon RA, Luyten FP, et al. (1998). Expression pattern of two Frizzled-related genes, Frzb-1 and Sfrp-1, during mouse embryogenesis suggests a role for modulating action of Wnt family members. Dev Dyn 212: 364-372.
    • (1998) Dev Dyn , vol.212 , pp. 364-372
    • Hoang, B.H.1    Thomas, J.T.2    Abdul-Karim, F.W.3    Correia, K.M.4    Conlon, R.A.5    Luyten, F.P.6
  • 83
    • 70149125015 scopus 로고    scopus 로고
    • Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation
    • Hoeppner LH, Secreto F., Jensen ED, Li X., Kahler RA, Westendorf JJ (2009 a). Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation J Cell Physiol 221: 480-489.
    • (2009) J Cell Physiol , vol.221 , pp. 480-489
    • Hoeppner, L.H.1    Secreto, F.2    Jensen, E.D.3    Li, X.4    Kahler, R.A.5    Westendorf, J.J.6
  • 85
    • 0034192176 scopus 로고    scopus 로고
    • The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing
    • Hovanes K., Li TW, Waterman ML (2000). The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing. Nucleic Acids Res 28: 1994-2003.
    • (2000) Nucleic Acids Res , vol.28 , pp. 1994-2003
    • Hovanes, K.1    Li, T.W.2    Waterman, M.L.3
  • 86
    • 33748849466 scopus 로고    scopus 로고
    • Control of stress propagation in the cytoplasm by prestress and loading frequency
    • Hu S., Wang N. (2006). Control of stress propagation in the cytoplasm by prestress and loading frequency. Mol Cell Biomech 3: 49-60.
    • (2006) Mol Cell Biomech , vol.3 , pp. 49-60
    • Hu, S.1    Wang, N.2
  • 87
    • 0142084723 scopus 로고    scopus 로고
    • Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells
    • Hu S., Chen J., Fabry B., Numaguchi Y., Gouldstone A., Ingber DE, et al. (2003). Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. Am J Physiol Cell Physiol 285: 1082-1090.
    • (2003) Am J Physiol Cell Physiol , vol.285 , pp. 1082-1090
    • Hu, S.1    Chen, J.2    Fabry, B.3    Numaguchi, Y.4    Gouldstone, A.5    Ingber, D.E.6
  • 88
    • 67649651479 scopus 로고    scopus 로고
    • The -9247 T/C polymorphism in the SOST upstream regulatory region that potentially affects C/EBPalpha and FOXA1 binding is associated with osteoporosis
    • Huang QY, Li GH, Kung AW (2009). The -9247 T/C polymorphism in the SOST upstream regulatory region that potentially affects C/EBPalpha and FOXA1 binding is associated with osteoporosis Bone 45: 289-294.
    • (2009) Bone , vol.45 , pp. 289-294
    • Huang, Q.Y.1    Li, G.H.2    Kung, A.W.3
  • 90
    • 0026545248 scopus 로고
    • Alveolar bone remodeling after tooth extraction in normal and osteopetrotic (ia) rats
    • Iizuka T., Miller SC, Marks SC Jr (1992). Alveolar bone remodeling after tooth extraction in normal and osteopetrotic (ia) rats. J Oral Pathol Med 21: 150-155.
    • (1992) J Oral Pathol Med , vol.21 , pp. 150-155
    • Iizuka, T.1    Miller, S.C.2    Marks Jr., S.C.3
  • 91
    • 0037383404 scopus 로고    scopus 로고
    • Tensegrity I. Cell structure and hierarchical systems biology
    • Ingber DE (2003). Tensegrity I. Cell structure and hierarchical systems biology. J Cell Sci 116 (Pt 7). 1157-1173.
    • (2003) J Cell Sci , vol.116 , Issue.7 , pp. 1157-1173
    • Ingber, D.E.1
  • 92
    • 45249093434 scopus 로고    scopus 로고
    • Tensegrity-based mechanosensing from macro to micro
    • Ingber DE (2008). Tensegrity-based mechanosensing from macro to micro. Prog Biophys Mol Biol 97: 163-179.
    • (2008) Prog Biophys Mol Biol , vol.97 , pp. 163-179
    • Ingber, D.E.1
  • 93
    • 65249165926 scopus 로고    scopus 로고
    • Remodeling of fracture callus in mice is consistent with mechanical loading and bone remodeling theory
    • Isaksson H., Grongroft I., Wilson W., van Donkelaar CC, van Rietbergen B., Tami A., et al. (2009). Remodeling of fracture callus in mice is consistent with mechanical loading and bone remodeling theory. J Orthop Res 27: 664-672.
    • (2009) J Orthop Res , vol.27 , pp. 664-672
    • Isaksson, H.1    Grongroft, I.2    Wilson, W.3    Van Donkelaar, C.C.4    Van Rietbergen, B.5    Tami, A.6
  • 94
    • 33748290174 scopus 로고    scopus 로고
    • Influence of forces on peri-implant bone
    • Isidor F. (2006). Influence of forces on peri-implant bone. Clin Oral Implants Res 17 (Suppl 2). 8-18.
    • (2006) Clin Oral Implants Res , vol.17 , Issue.2 , pp. 8-18
    • Isidor, F.1
  • 96
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/ beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho EH, Zhang T., Domon C., Joo CK, Freund JN, Costantini F. (2002). Wnt/ beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 22: 1172-1183.
    • (2002) Mol Cell Biol , vol.22 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5    Costantini, F.6
  • 97
    • 0038485600 scopus 로고    scopus 로고
    • Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter
    • Kahler RA, Westendorf JJ (2003). Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter. J Biol Chem 278: 11937-11944.
    • (2003) J Biol Chem , vol.278 , pp. 11937-11944
    • Kahler, R.A.1    Westendorf, J.J.2
  • 99
    • 33748654584 scopus 로고    scopus 로고
    • Growth factor delivery for oral and periodontal tissue engineering
    • Kaigler D., Cirelli JA, Giannobile WV (2006). Growth factor delivery for oral and periodontal tissue engineering. Expert Opin Drug Deliv 3: 647-662.
    • (2006) Expert Opin Drug Deliv , vol.3 , pp. 647-662
    • Kaigler, D.1    Cirelli, J.A.2    Giannobile, W.V.3
  • 100
    • 0033604585 scopus 로고    scopus 로고
    • The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB
    • Kandel ES, Hay N. (1999). The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp Cell Res 253: 210-229.
    • (1999) Exp Cell Res , vol.253 , pp. 210-229
    • Kandel, E.S.1    Hay, N.2
  • 101
    • 0036841293 scopus 로고    scopus 로고
    • Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage
    • Kandel ES, Skeen J., Majewski N., Di Cristofano A., Pandolfi PP, Feliciano CS, et al. (2002). Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage. Mol Cell Biol 22: 7831-7841.
    • (2002) Mol Cell Biol , vol.22 , pp. 7831-7841
    • Kandel, E.S.1    Skeen, J.2    Majewski, N.3    Di Cristofano, A.4    Pandolfi, P.P.5    Feliciano, C.S.6
  • 102
    • 67650514306 scopus 로고    scopus 로고
    • Bili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6
    • Kategaya LS, Changkakoty B., Biechele T., Conrad WH, Kaykas A., Dasgupta R., et al. (2009). Bili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6. PLoS One 4 (7). e6129.
    • (2009) PLoS One , vol.4 , Issue.7 , pp. 6129
    • Kategaya, L.S.1    Changkakoty, B.2    Biechele, T.3    Conrad, W.H.4    Kaykas, A.5    Dasgupta, R.6
  • 103
    • 21844467220 scopus 로고    scopus 로고
    • SOST is a target gene for PTH in bone
    • Keller H., Kneissel M. (2005). SOST is a target gene for PTH in bone. Bone 37: 148-158.
    • (2005) Bone , vol.37 , pp. 148-158
    • Keller, H.1    Kneissel, M.2
  • 104
    • 34748861187 scopus 로고    scopus 로고
    • Regulation of Wnt signalling by receptor-mediated endocytosis
    • Kikuchi A., Yamamoto H. (2007). Regulation of Wnt signalling by receptor-mediated endocytosis. J Biochem 141: 443-451.
    • (2007) J Biochem , vol.141 , pp. 443-451
    • Kikuchi, A.1    Yamamoto, H.2
  • 106
    • 4644291445 scopus 로고    scopus 로고
    • Biomechanical aspects of marginal bone resorption around osseointegrated implants: Considerations based on a three-dimensional finite element analysis
    • Kitamura E., Stegaroiu R., Nomura S., Miyakawa O. (2004). Biomechanical aspects of marginal bone resorption around osseointegrated implants: considerations based on a three-dimensional finite element analysis. Clin Oral Implants Res 15: 401-412.
    • (2004) Clin Oral Implants Res , vol.15 , pp. 401-412
    • Kitamura, E.1    Stegaroiu, R.2    Nomura, S.3    Miyakawa, O.4
  • 107
    • 40849083718 scopus 로고    scopus 로고
    • Evaluation of the cylinder implant thread height and width: A 3-dimensional finite element analysis
    • Kong L., Hu K., Li D., Song Y., Yang J., Wu Z., et al. (2008). Evaluation of the cylinder implant thread height and width: a 3-dimensional finite element analysis. Int J Oral Maxillofac Implants 23: 65-74.
    • (2008) Int J Oral Maxillofac Implants , vol.23 , pp. 65-74
    • Kong, L.1    Hu, K.2    Li, D.3    Song, Y.4    Yang, J.5    Wu, Z.6
  • 108
    • 0029741097 scopus 로고    scopus 로고
    • Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development
    • Kratochwil K., Dull M., Farinas I., Galceran J., Grosschedl R. (1996). Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development. Genes Dev 10: 1382-1394.
    • (1996) Genes Dev , vol.10 , pp. 1382-1394
    • Kratochwil, K.1    Dull, M.2    Farinas, I.3    Galceran, J.4    Grosschedl, R.5
  • 111
    • 0034845958 scopus 로고    scopus 로고
    • PKB/Akt: A key mediator of cell proliferation, survival and insulin responses
    • Lawlor MA, Alessi DR (2001). PKB/Akt: a key mediator of cell proliferation, survival and insulin responses ? J Cell Sci 114 (Pt 16). 2903-2910.
    • (2001) J Cell Sci , vol.114 , Issue.16 , pp. 2903-2910
    • Lawlor, M.A.1    Alessi, D.R.2
  • 112
    • 4243067196 scopus 로고    scopus 로고
    • The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway
    • Lee E., Salic A., Kruger R., Heinrich R., Kirschner MW (2003). The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS Biol 1 (1). E10.
    • (2003) PLoS Biol , vol.1 , Issue.1 , pp. 10
    • Lee, E.1    Salic, A.2    Kruger, R.3    Heinrich, R.4    Kirschner, M.W.5
  • 113
    • 0042265549 scopus 로고    scopus 로고
    • Endocrinology: Bone adaptation requires oestrogen receptor-alpha
    • Lee K., Jessop H., Suswillo R., Zaman G., Lanyon L. (2003). Endocrinology: bone adaptation requires oestrogen receptor-alpha. Nature 424: 389.
    • (2003) Nature , vol.424 , pp. 389
    • Lee, K.1    Jessop, H.2    Suswillo, R.3    Zaman, G.4    Lanyon, L.5
  • 114
    • 4444314796 scopus 로고    scopus 로고
    • The adaptive response of bone to mechanical loading in female transgenic mice is deficient in the absence of oestrogen receptor-alpha and -beta
    • Lee KC, Jessop H., Suswillo R., Zaman G., Lanyon LE (2004). The adaptive response of bone to mechanical loading in female transgenic mice is deficient in the absence of oestrogen receptor-alpha and -beta. J Endocrinol 182: 193-201.
    • (2004) J Endocrinol , vol.182 , pp. 193-201
    • Lee, K.C.1    Jessop, H.2    Suswillo, R.3    Zaman, G.4    Lanyon, L.E.5
  • 115
    • 0037077266 scopus 로고    scopus 로고
    • Activation of AXIN2 expression by beta-catenin-T cell factor.A feedback repressor pathway regulating Wnt signaling
    • Leung JY, Kolligs FT, Wu R., Zhai Y., Kuick R., Hanash S., et al. (2002). Activation of AXIN2 expression by beta-catenin-T cell factor.A feedback repressor pathway regulating Wnt signaling. J Biol Chem 277: 21657-21665.
    • (2002) J Biol Chem , vol.277 , pp. 21657-21665
    • Leung, J.Y.1    Kolligs, F.T.2    Wu, R.3    Zhai, Y.4    Kuick, R.5    Hanash, S.6
  • 118
    • 34250201079 scopus 로고    scopus 로고
    • Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling
    • Li FQ, Singh AM, Mofunanya A., Love D., Terada N., Moon RT, et al. (2007). Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling. Mol Cell Biol 27: 4347-4354.
    • (2007) Mol Cell Biol , vol.27 , pp. 4347-4354
    • Li, F.Q.1    Singh, A.M.2    Mofunanya, A.3    Love, D.4    Terada, N.5    Moon, R.T.6
  • 119
    • 46449112475 scopus 로고    scopus 로고
    • Chibby cooperates with 14-3-3 to regulate beta-catenin subcellular distribution and signaling activity
    • Li FQ, Mofunanya A., Harris K., Takemaru K. (2008). Chibby cooperates with 14-3-3 to regulate beta-catenin subcellular distribution and signaling activity. J Cell Biol 181: 1141-1154.
    • (2008) J Cell Biol , vol.181 , pp. 1141-1154
    • Li, F.Q.1    Mofunanya, A.2    Harris, K.3    Takemaru, K.4
  • 120
    • 25144448701 scopus 로고    scopus 로고
    • Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation
    • Li X., Liu P., Liu W., Maye P., Zhang J., Zhang Y., et al. (2005 a). Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation. Nat Genet 37: 945-952.
    • (2005) Nat Genet , vol.37 , pp. 945-952
    • Li, X.1    Liu, P.2    Liu, W.3    Maye, P.4    Zhang, J.5    Zhang, Y.6
  • 121
    • 21244480924 scopus 로고    scopus 로고
    • Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
    • Li X., Zhang Y., Kang H., Liu W., Liu P., Zhang J., et al. (2005 b). Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. J Biol Chem 280: 19883-19887.
    • (2005) J Biol Chem , vol.280 , pp. 19883-19887
    • Li, X.1    Zhang, Y.2    Kang, H.3    Liu, W.4    Liu, P.5    Zhang, J.6
  • 122
    • 44449099165 scopus 로고    scopus 로고
    • Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
    • Li X., Ominsky MS, Niu QT, Sun N., Daugherty B., DAgostin D., et al. (2008). Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength. J Bone Miner Res 23: 860-869.
    • (2008) J Bone Miner Res , vol.23 , pp. 860-869
    • Li, X.1    Ominsky, M.S.2    Niu, Q.T.3    Sun, N.4    Daugherty, B.5    Dagostin, D.6
  • 123
    • 65549152230 scopus 로고    scopus 로고
    • Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis
    • Li X., Ominsky MS, Warmington KS, Morony S., Gong J., Cao J., et al. (2009). Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis. J Bone Miner Res 24: 578-588.
    • (2009) J Bone Miner Res , vol.24 , pp. 578-588
    • Li, X.1    Ominsky, M.S.2    Warmington, K.S.3    Morony, S.4    Gong, J.5    Cao, J.6
  • 124
    • 70349934212 scopus 로고    scopus 로고
    • Sclerostin mediates bone response to mechanical unloading via antagonizing Wnt/ beta-catenin signaling
    • Lin C., Jiang X., Dai Z., Guo X., Weng T., Wang J., et al. (2009). Sclerostin mediates bone response to mechanical unloading via antagonizing Wnt/ beta-catenin signaling. J Bone Miner Res 24: 1651-1661.
    • (2009) J Bone Miner Res , vol.24 , pp. 1651-1661
    • Lin, C.1    Jiang, X.2    Dai, Z.3    Guo, X.4    Weng, T.5    Wang, J.6
  • 125
    • 33845625248 scopus 로고    scopus 로고
    • Craniosynostosis caused by Axin2 deficiency is mediated through distinct functions of beta-catenin in proliferation and differentiation
    • Liu B., Yu HM, Hsu W. (2007). Craniosynostosis caused by Axin2 deficiency is mediated through distinct functions of beta-catenin in proliferation and differentiation. Dev Biol 301: 298-308.
    • (2007) Dev Biol , vol.301 , pp. 298-308
    • Liu, B.1    Yu, H.M.2    Hsu, W.3
  • 126
    • 37349092090 scopus 로고    scopus 로고
    • Wnt/ beta-catenin signaling directs multiple stages of tooth morphogenesis
    • Liu F., Chu EY, Watt B., Zhang Y., Gallant NM, Andl T., et al. (2008). Wnt/ beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol 313: 210-224.
    • (2008) Dev Biol , vol.313 , pp. 210-224
    • Liu, F.1    Chu, E.Y.2    Watt, B.3    Zhang, Y.4    Gallant, N.M.5    Andl, T.6
  • 127
    • 58149260269 scopus 로고    scopus 로고
    • Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
    • Lo Celso C., Fleming HE, Wu JW, Zhao CX, Miake-Lye S., Fujisaki J., et al. (2009). Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature 457: 92-96.
    • (2009) Nature , vol.457 , pp. 92-96
    • Lo Celso, C.1    Fleming, H.E.2    Wu, J.W.3    Zhao, C.X.4    Miake-Lye, S.5    Fujisaki, J.6
  • 128
    • 0025352299 scopus 로고
    • Arrestin: A protein that regulates beta-adrenergic receptor function
    • Lohse MJ, Benovic JL, Codina J., Caron MG, Lefkowitz RJ (1990). Arrestin: a protein that regulates beta-adrenergic receptor function. Science 248: 1547-1550.
    • (1990) Science , vol.248 , pp. 1547-1550
    • Lohse, M.J.1    Benovic, J.L.2    Codina, J.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 129
    • 34250340986 scopus 로고    scopus 로고
    • A new era in periodontal and periimplant regeneration: Use of growth-factor enhanced matrices incorporating rhPDGF
    • Lynch SE, Wisner-Lynch L., Nevins M., Nevins ML (2006). A new era in periodontal and periimplant regeneration: use of growth-factor enhanced matrices incorporating rhPDGF. Compend Contin Educ Dent 27: 672-678.
    • (2006) Compend Contin Educ Dent , vol.27 , pp. 672-678
    • Lynch, S.E.1    Wisner-Lynch, L.2    Nevins, M.3    Nevins, M.L.4
  • 130
    • 47049121052 scopus 로고    scopus 로고
    • Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6
    • MacDonald BT, Yokota C., Tamai K., Zeng X., He X. (2008). Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6. J Biol Chem 283: 16115-16123.
    • (2008) J Biol Chem , vol.283 , pp. 16115-16123
    • MacDonald, B.T.1    Yokota, C.2    Tamai, K.3    Zeng, X.4    He, X.5
  • 131
    • 0034120134 scopus 로고    scopus 로고
    • High intensity resistance training: Effects on bone in older men and women
    • Maddalozzo GF, Snow CM (2000). High intensity resistance training: effects on bone in older men and women. Calcif Tissue Int 66: 399-404.
    • (2000) Calcif Tissue Int , vol.66 , pp. 399-404
    • Maddalozzo, G.F.1    Snow, C.M.2
  • 132
    • 0029147728 scopus 로고
    • Quantitative evaluation on osteocyte canalicular density in human secondary osteons
    • Marotti G., Ferretti M., Remaggi F., Palumbo C. (1995). Quantitative evaluation on osteocyte canalicular density in human secondary osteons. Bone 16: 125-128.
    • (1995) Bone , vol.16 , pp. 125-128
    • Marotti, G.1    Ferretti, M.2    Remaggi, F.3    Palumbo, C.4
  • 133
    • 61449210874 scopus 로고    scopus 로고
    • Wnt signaling and the evolution of embryonic posterior development
    • Martin BL, Kimelman D. (2009). Wnt signaling and the evolution of embryonic posterior development Curr Biol 19: 215-219.
    • (2009) Curr Biol , vol.19 , pp. 215-219
    • Martin, B.L.1    Kimelman, D.2
  • 134
    • 56349142989 scopus 로고    scopus 로고
    • Bone remodelling: Its local regulation and the emergence of bone fragility
    • Martin TJ, Seeman E. (2008). Bone remodelling: its local regulation and the emergence of bone fragility. Best Pract Res Clin Endocrinol Metab 22: 701-722.
    • (2008) Best Pract Res Clin Endocrinol Metab , vol.22 , pp. 701-722
    • Martin, T.J.1    Seeman, E.2
  • 135
    • 67849084531 scopus 로고    scopus 로고
    • Cross-talk among bone cells
    • Matsuo K. (2009). Cross-talk among bone cells. Curr Opin Nephrol Hypertens 18: 292-297.
    • (2009) Curr Opin Nephrol Hypertens , vol.18 , pp. 292-297
    • Matsuo, K.1
  • 136
    • 42749088910 scopus 로고    scopus 로고
    • Osteoclast-osteoblast communication
    • Matsuo K., Irie N. (2008). Osteoclast-osteoblast communication. Arch Biochem Biophys 473: 201-209.
    • (2008) Arch Biochem Biophys , vol.473 , pp. 201-209
    • Matsuo, K.1    Irie, N.2
  • 137
    • 65349089448 scopus 로고    scopus 로고
    • Putative signaling action of amelogenin utilizes the Wnt/beta-catenin pathway
    • Matsuzawa M., Sheu TJ, Lee YJ, Chen M., Li TF, Huang CT, et al. (2009). Putative signaling action of amelogenin utilizes the Wnt/beta-catenin pathway. J Periodontal Res 44: 289-296.
    • (2009) J Periodontal Res , vol.44 , pp. 289-296
    • Matsuzawa, M.1    Sheu, T.J.2    Lee, Y.J.3    Chen, M.4    Li, T.F.5    Huang, C.T.6
  • 138
    • 2942635731 scopus 로고    scopus 로고
    • Stimulating effect of implant loading on surrounding bone. Comparison of three numerical models and validation by in vivo data
    • Mellal A., Wiskott HW, Botsis J., Scherrer SS, Belser UC (2004). Stimulating effect of implant loading on surrounding bone. Comparison of three numerical models and validation by in vivo data. Clin Oral Implants Res 15: 239-248.
    • (2004) Clin Oral Implants Res , vol.15 , pp. 239-248
    • Mellal, A.1    Wiskott, H.W.2    Botsis, J.3    Scherrer, S.S.4    Belser, U.C.5
  • 139
    • 47249145235 scopus 로고    scopus 로고
    • Growth and the modeling/remodeling of the alveolar bone of the rat incisor
    • Hoboken )
    • Merzel J., Salmon CR (2008). Growth and the modeling/remodeling of the alveolar bone of the rat incisor. Anat Rec (Hoboken) 291: 827-834.
    • (2008) Anat Rec , vol.291 , pp. 827-834
    • Merzel, J.1    Salmon, C.R.2
  • 140
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
    • Mikels AJ, Nusse R. (2006). Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol 4 (4). e115.
    • (2006) PLoS Biol , vol.4 , Issue.4 , pp. 115
    • Mikels, A.J.1    Nusse, R.2
  • 141
    • 69249214000 scopus 로고    scopus 로고
    • Is Wnt-signalling the final common pathway leading to bone formation?
    • Milat F., Ng KW (2009). Is Wnt-signalling the final common pathway leading to bone formation? Mol Cell Endocrinol 310: 52-62.
    • (2009) Mol Cell Endocrinol , vol.310 , pp. 52-62
    • Milat, F.1    Ng, K.W.2
  • 142
  • 143
    • 0030893352 scopus 로고    scopus 로고
    • Structurally related receptors and antagonists compete for secreted Wnt ligands
    • Moon RT, Brown JD, Yang-Snyder JA, Miller JR (1997). Structurally related receptors and antagonists compete for secreted Wnt ligands. Cell 88: 725-728.
    • (1997) Cell , vol.88 , pp. 725-728
    • Moon, R.T.1    Brown, J.D.2    Yang-Snyder, J.A.3    Miller, J.R.4
  • 144
    • 62849106337 scopus 로고    scopus 로고
    • Beta-catenin hits chromatin: Regulation of Wnt target gene activation
    • Mosimann C., Hausmann G., Basler K. (2009). Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat Rev Mol Cell Biol 10: 276-786.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 276-786
    • Mosimann, C.1    Hausmann, G.2    Basler, K.3
  • 145
    • 63449096161 scopus 로고    scopus 로고
    • The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading
    • Moustafa A., Sugiyama T., Saxon LK, Zaman G., Sunters A., Armstrong VJ, et al. (2009). The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading. Bone 44: 930-935.
    • (2009) Bone , vol.44 , pp. 930-935
    • Moustafa, A.1    Sugiyama, T.2    Saxon, L.K.3    Zaman, G.4    Sunters, A.5    Armstrong, V.J.6
  • 146
    • 63449121771 scopus 로고    scopus 로고
    • Wnt signaling inhibits cementoblast differentiation and promotes proliferation
    • Nemoto E., Koshikawa Y., Kanaya S., Tsuchiya M., Tamura M., Somerman MJ, et al. (2009). Wnt signaling inhibits cementoblast differentiation and promotes proliferation. Bone 44: 805-812.
    • (2009) Bone , vol.44 , pp. 805-812
    • Nemoto, E.1    Koshikawa, Y.2    Kanaya, S.3    Tsuchiya, M.4    Tamura, M.5    Somerman, M.J.6
  • 147
    • 0242320424 scopus 로고    scopus 로고
    • Periodontal regeneration in humans using recombinant human platelet-derived growth factor-BB (rhPDGF-BB) and allogenic bone
    • Nevins M., Camelo M., Nevins ML, Schenk RK, Lynch SE (2003). Periodontal regeneration in humans using recombinant human platelet-derived growth factor-BB (rhPDGF-BB) and allogenic bone. J Periodontol 74: 1282-1292.
    • (2003) J Periodontol , vol.74 , pp. 1282-1292
    • Nevins, M.1    Camelo, M.2    Nevins, M.L.3    Schenk, R.K.4    Lynch, S.E.5
  • 148
    • 68549135137 scopus 로고    scopus 로고
    • Clinical outcomes of sinus floor augmentation for implant placement using autogenous bone or bone substitutes: A systematic review
    • Nkenke E., Stelzle F. (2009). Clinical outcomes of sinus floor augmentation for implant placement using autogenous bone or bone substitutes: a systematic review. Clin Oral Implants Res 20 (Suppl 4). 124-133.
    • (2009) Clin Oral Implants Res , vol.20 , Issue.4 , pp. 124-133
    • Nkenke, E.1    Stelzle, F.2
  • 149
    • 56849118516 scopus 로고    scopus 로고
    • Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis
    • Nogueira V., Park Y., Chen CC, Xu PZ, Chen ML, Tonic I., et al. (2008). Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis. Cancer Cell 14: 458-470.
    • (2008) Cancer Cell , vol.14 , pp. 458-470
    • Nogueira, V.1    Park, Y.2    Chen, C.C.3    Xu, P.Z.4    Chen, M.L.5    Tonic, I.6
  • 150
    • 43049144313 scopus 로고    scopus 로고
    • Wnt signaling and stem cell control
    • Nusse R. (2008). Wnt signaling and stem cell control. Cell Res 18: 523-527.
    • (2008) Cell Res , vol.18 , pp. 523-527
    • Nusse, R.1
  • 151
    • 1642546419 scopus 로고    scopus 로고
    • Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength
    • OBrien CA, Jia D., Plotkin LI, Bellido T., Powers CC, Stewart SA, et al. (2004). Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength. Endocrinology 145: 1835-1841.
    • (2004) Endocrinology , vol.145 , pp. 1835-1841
    • Obrien, C.A.1    Jia, D.2    Plotkin, L.I.3    Bellido, T.4    Powers, C.C.5    Stewart, S.A.6
  • 153
    • 27744470619 scopus 로고    scopus 로고
    • Modern analysis of bone loss mechanisms in microgravity
    • Oganov VS (2004). Modern analysis of bone loss mechanisms in microgravity. J Gravit Physiol 11 :P 143 - P146.
    • (2004) J Gravit Physiol , vol.11
    • Oganov, V.S.1
  • 154
    • 10744219743 scopus 로고    scopus 로고
    • The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/ JNK signalling pathway
    • Oishi I., Suzuki H., Onishi N., Takada R., Kani S., Ohkawara B., et al. (2003). The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/ JNK signalling pathway. Genes Cells 8: 645-654.
    • (2003) Genes Cells , vol.8 , pp. 645-654
    • Oishi, I.1    Suzuki, H.2    Onishi, N.3    Takada, R.4    Kani, S.5    Ohkawara, B.6
  • 155
    • 0036024503 scopus 로고    scopus 로고
    • The canalicular structure of compact bone in the rat at different ages
    • Okada S., Yoshida S., Ashrafi SH, Schraufnagel DE (2002). The canalicular structure of compact bone in the rat at different ages. Microsc Microanal 8: 104-115.
    • (2002) Microsc Microanal , vol.8 , pp. 104-115
    • Okada, S.1    Yoshida, S.2    Ashrafi, S.H.3    Schraufnagel, D.E.4
  • 156
    • 70350447498 scopus 로고    scopus 로고
    • Histomorphometric evaluation of implant design as a key factor in periimplant bone response: A preliminary study in a dog model
    • Orsini E., Salgarello S., Bubalo M., Lazic Z., Trire A., Martini D., et al. (2009). Histomorphometric evaluation of implant design as a key factor in periimplant bone response: a preliminary study in a dog model. Minerva Stomatol 58: 263-275.
    • (2009) Minerva Stomatol , vol.58 , pp. 263-275
    • Orsini, E.1    Salgarello, S.2    Bubalo, M.3    Lazic, Z.4    Trire, A.5    Martini, D.6
  • 157
    • 68849117424 scopus 로고    scopus 로고
    • Identification of differentially expressed genes between osteoblasts and osteocytes
    • Paic F., Igwe J., Nori R., Kronenberg M., Franceschetti T., Harrington P., et al. (2009). Identification of differentially expressed genes between osteoblasts and osteocytes. Bone 45: 682-692.
    • (2009) Bone , vol.45 , pp. 682-692
    • Paic, F.1    Igwe, J.2    Nori, R.3    Kronenberg, M.4    Franceschetti, T.5    Harrington, P.6
  • 159
    • 0032493729 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway
    • Pap M., Cooper GM (1998). Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway. J Biol Chem 273 (32). 19929-19932.
    • (1998) J Biol Chem , vol.273 , Issue.32 , pp. 19929-19932
    • Pap, M.1    Cooper, G.M.2
  • 160
    • 0036140080 scopus 로고    scopus 로고
    • Targeted and nontargeted bone remodeling: Relationship to basic multicellular unit origination and progression
    • Parfitt AM (2002). Targeted and nontargeted bone remodeling: relationship to basic multicellular unit origination and progression. Bone 30: 5-7.
    • (2002) Bone , vol.30 , pp. 5-7
    • Parfitt, A.M.1
  • 162
    • 34548204415 scopus 로고    scopus 로고
    • Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis
    • Plotkin LI, Manolagas SC, Bellido T. (2007). Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis. J Biol Chem 282: 24120-24130.
    • (2007) J Biol Chem , vol.282 , pp. 24120-24130
    • Plotkin, L.I.1    Manolagas, S.C.2    Bellido, T.3
  • 163
    • 54249141694 scopus 로고    scopus 로고
    • Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo
    • Plotkin LI, Lezcano V., Thostenson J., Weinstein RS, Manolagas SC, Bellido T. (2008). Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo. J Bone Miner Res 23: 1712-1721.
    • (2008) J Bone Miner Res , vol.23 , pp. 1712-1721
    • Plotkin, L.I.1    Lezcano, V.2    Thostenson, J.3    Weinstein, R.S.4    Manolagas, S.C.5    Bellido, T.6
  • 165
    • 47249140444 scopus 로고    scopus 로고
    • Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: A potential mechanism underlying osteolytic bone lesions in multiple myeloma
    • Qiang YW, Chen Y., Stephens O., Brown N., Chen B., Epstein J., et al. (2008). Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma. Blood 112: 196-207.
    • (2008) Blood , vol.112 , pp. 196-207
    • Qiang, Y.W.1    Chen, Y.2    Stephens, O.3    Brown, N.4    Chen, B.5    Epstein, J.6
  • 166
    • 27144458524 scopus 로고    scopus 로고
    • Wnt signalling pathway: A new target for the treatment of osteoporosis
    • Rawadi G., Roman-Roman S. (2005). Wnt signalling pathway: a new target for the treatment of osteoporosis. Expert Opin Ther Targets 9: 1063-1077.
    • (2005) Expert Opin Ther Targets , vol.9 , pp. 1063-1077
    • Rawadi, G.1    Roman-Roman, S.2
  • 167
    • 41949089764 scopus 로고    scopus 로고
    • Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin
    • Robling AG, Niziolek PJ, Baldridge LA, Condon KW, Allen MR, Alam I., et al. (2008). Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. J Biol Chem 283: 5866-5875.
    • (2008) J Biol Chem , vol.283 , pp. 5866-5875
    • Robling, A.G.1    Niziolek, P.J.2    Baldridge, L.A.3    Condon, K.W.4    Allen, M.R.5    Alam, I.6
  • 168
    • 33748768971 scopus 로고    scopus 로고
    • Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors
    • Rodda SJ, McMahon AP (2006). Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development 133: 3231-3244.
    • (2006) Development , vol.133 , pp. 3231-3244
    • Rodda, S.J.1    McMahon, A.P.2
  • 169
    • 73949151579 scopus 로고    scopus 로고
    • Role of Wnt signaling in the biology of the periodontium
    • Rooker SM, Liu B., Helms JA (2009). Role of Wnt signaling in the biology of the periodontium Dev Dyn 239: 140-147.
    • (2009) Dev Dyn , vol.239 , pp. 140-147
    • Rooker, S.M.1    Liu, B.2    Helms, J.A.3
  • 171
    • 0033167366 scopus 로고    scopus 로고
    • Expression of Wnt signalling pathway genes during tooth development
    • Sarkar L., Sharpe PT (1999). Expression of Wnt signalling pathway genes during tooth development. Mech Dev 85: 197-200.
    • (1999) Mech Dev , vol.85 , pp. 197-200
    • Sarkar, L.1    Sharpe, P.T.2
  • 172
    • 0034438335 scopus 로고    scopus 로고
    • Inhibition of Wnt signaling by exogenous Mfrzb1 protein affects molar tooth size
    • Sarkar L., Sharpe PT (2000). Inhibition of Wnt signaling by exogenous Mfrzb1 protein affects molar tooth size. J Dent Res 79: 920-925.
    • (2000) J Dent Res , vol.79 , pp. 920-925
    • Sarkar, L.1    Sharpe, P.T.2
  • 173
    • 33747674263 scopus 로고    scopus 로고
    • The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment
    • Sawakami K., Robling AG, Ai M., Pitner ND, Liu D., Warden SJ, et al. (2006). The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment. J Biol Chem 281: 23698-23711.
    • (2006) J Biol Chem , vol.281 , pp. 23698-23711
    • Sawakami, K.1    Robling, A.G.2    Ai, M.3    Pitner, N.D.4    Liu, D.5    Warden, S.J.6
  • 174
    • 39149133149 scopus 로고    scopus 로고
    • Wnt/beta-catenin inhibits dental pulp stem cell differentiation
    • Scheller EL, Chang J., Wang CY (2008). Wnt/beta-catenin inhibits dental pulp stem cell differentiation. J Dent Res 87: 126-130.
    • (2008) J Dent Res , vol.87 , pp. 126-130
    • Scheller, E.L.1    Chang, J.2    Wang, C.Y.3
  • 175
    • 0028943780 scopus 로고
    • A constitutively active mutant PTHPTHrP receptor in Jansen-type metaphyseal chondrodysplasia
    • Schipani E., Kruse K., Juppner H. (1995). A constitutively active mutant PTHPTHrP receptor in Jansen-type metaphyseal chondrodysplasia. Science 268: 98-100.
    • (1995) Science , vol.268 , pp. 98-100
    • Schipani, E.1    Kruse, K.2    Juppner, H.3
  • 176
    • 59949090255 scopus 로고    scopus 로고
    • Wnt signaling pathways meet Rho GTPases
    • Schlessinger K., Hall A., Tolwinski N. (2009). Wnt signaling pathways meet Rho GTPases Genes Dev 23: 265-277.
    • (2009) Genes Dev , vol.23 , pp. 265-277
    • Schlessinger, K.1    Hall, A.2    Tolwinski, N.3
  • 177
    • 50249102241 scopus 로고    scopus 로고
    • Regeneration of periodontal tissues: Combinations of barrier membranes and grafting materials- biological foundation and preclinical evidence: A systematic review
    • Sculean A., Nikolidakis D., Schwarz F. (2008 a). Regeneration of periodontal tissues: combinations of barrier membranes and grafting materials- biological foundation and preclinical evidence: a systematic review. J Clin Periodontol 35 (8 Suppl). 106S - 116S.
    • (2008) J Clin Periodontol , vol.35 , Issue.8
    • Sculean, A.1    Nikolidakis, D.2    Schwarz, F.3
  • 178
    • 49749108573 scopus 로고    scopus 로고
    • Ten-year results following treatment of intra-bony defects with enamel matrix proteins and guided tissue regeneration
    • Sculean A., Kiss A., Miliauskaite A., Schwarz F., Arweiler NB, Hannig M. (2008 b). Ten-year results following treatment of intra-bony defects with enamel matrix proteins and guided tissue regeneration. J Clin Periodontol 35: 817-824.
    • (2008) J Clin Periodontol , vol.35 , pp. 817-824
    • Sculean, A.1    Kiss, A.2    Miliauskaite, A.3    Schwarz, F.4    Arweiler, N.B.5    Hannig, M.6
  • 180
    • 55549123031 scopus 로고    scopus 로고
    • Adaptation of connexin 43-hemichannel prostaglandin release to mechanical loading
    • Siller-Jackson AJ, Burra S., Gu S., Xia X., Bonewald LF, Sprague E., et al. (2008). Adaptation of connexin 43-hemichannel prostaglandin release to mechanical loading. J Biol Chem 283: 26374-26382.
    • (2008) J Biol Chem , vol.283 , pp. 26374-26382
    • Siller-Jackson, A.J.1    Burra, S.2    Gu, S.3    Xia, X.4    Bonewald, L.F.5    Sprague, E.6
  • 181
    • 0041843897 scopus 로고    scopus 로고
    • Mechanical strain increases cell stiffness through cytoskeletal filament reorganization
    • Smith PG, Deng L., Fredberg JJ, Maksym GN (2003). Mechanical strain increases cell stiffness through cytoskeletal filament reorganization. Am J Physiol Lung Cell Mol Physiol 285: 456-463.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285 , pp. 456-463
    • Smith, P.G.1    Deng, L.2    Fredberg, J.J.3    Maksym, G.N.4
  • 182
    • 12544258956 scopus 로고    scopus 로고
    • Bone markers, calcium metabolism, and calcium kinetics during extended-duration space flight on the Mir space station
    • Smith SM, Wastney ME, OBrien KO, Morukov BV, Larina IM, Abrams SA, et al. (2005). Bone markers, calcium metabolism, and calcium kinetics during extended-duration space flight on the Mir space station. J Bone Miner Res 20: 208-218.
    • (2005) J Bone Miner Res , vol.20 , pp. 208-218
    • Smith, S.M.1    Wastney, M.E.2    Obrien, K.O.3    Morukov, B.V.4    Larina, I.M.5    Abrams, S.A.6
  • 183
    • 58849090069 scopus 로고    scopus 로고
    • Signaling networks that control the lineage commitment and differentiation of bone cells
    • Soltanoff CS, Yang S., Chen W., Li YP (2009). Signaling networks that control the lineage commitment and differentiation of bone cells Crit Rev Eukaryot Gene Expr 19: 1-46.
    • (2009) Crit Rev Eukaryot Gene Expr , vol.19 , pp. 1-46
    • Soltanoff, C.S.1    Yang, S.2    Chen, W.3    Li, Y.P.4
  • 184
    • 0033533978 scopus 로고    scopus 로고
    • The role of prestress and architecture of the cytoskeleton and deformability of cytoskeletal filaments in mechanics of adherent cells: A quantitative analysis
    • Stamenovic D., Coughlin MF (1999). The role of prestress and architecture of the cytoskeleton and deformability of cytoskeletal filaments in mechanics of adherent cells: a quantitative analysis. J Theor Biol 201: 63-74.
    • (1999) J Theor Biol , vol.201 , pp. 63-74
    • Stamenovic, D.1    Coughlin, M.F.2
  • 186
    • 34247154612 scopus 로고    scopus 로고
    • Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells
    • Storm MP, Bone HK, Beck CG, Bourillot PY, Schreiber V., Damiano T., et al. (2007). Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells. J Biol Chem 282: 6265-6273.
    • (2007) J Biol Chem , vol.282 , pp. 6265-6273
    • Storm, M.P.1    Bone, H.K.2    Beck, C.G.3    Bourillot, P.Y.4    Schreiber, V.5    Damiano, T.6
  • 188
    • 0242515751 scopus 로고    scopus 로고
    • Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway
    • Takemaru K., Yamaguchi S., Lee YS, Zhang Y., Carthew RW, Moon RT (2003). Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway. Nature 422: 905-909.
    • (2003) Nature , vol.422 , pp. 905-909
    • Takemaru, K.1    Yamaguchi, S.2    Lee, Y.S.3    Zhang, Y.4    Carthew, R.W.5    Moon, R.T.6
  • 189
    • 0034727104 scopus 로고    scopus 로고
    • LDL-receptor-related proteins in Wnt signal transduction
    • Tamai K., Semenov M., Kato Y., Spokony R., Liu C., Katsuyama Y., et al. (2000). LDL-receptor-related proteins in Wnt signal transduction. Nature 407: 530-535.
    • (2000) Nature , vol.407 , pp. 530-535
    • Tamai, K.1    Semenov, M.2    Kato, Y.3    Spokony, R.4    Liu, C.5    Katsuyama, Y.6
  • 191
    • 72949110602 scopus 로고    scopus 로고
    • BMP9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signaling
    • Tang N., Song WX, Luo J., Luo X., Chen J., Sharff KA, et al. (2009). BMP9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signaling. J Cell Mol Med 13 (8b). 2448-2464.
    • (2009) J Cell Mol Med , vol.13 , Issue.8 B , pp. 2448-2464
    • Tang, N.1    Song, W.X.2    Luo, J.3    Luo, X.4    Chen, J.5    Sharff, K.A.6
  • 192
    • 34249657953 scopus 로고    scopus 로고
    • Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction
    • Tatsumi S., Ishii K., Amizuka N., Li M., Kobayashi T., Kohno K., et al. (2007). Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction. Cell Metab 5: 464-475.
    • (2007) Cell Metab , vol.5 , pp. 464-475
    • Tatsumi, S.1    Ishii, K.2    Amizuka, N.3    Li, M.4    Kobayashi, T.5    Kohno, K.6
  • 193
    • 57449116758 scopus 로고    scopus 로고
    • Do osteocytes contribute to bone mineral homeostasis? Osteocytic osteolysis revisited
    • Teti A., Zallone A. (2009). Do osteocytes contribute to bone mineral homeostasis? Osteocytic osteolysis revisited Bone 44: 11-16.
    • (2009) Bone , vol.44 , pp. 11-16
    • Teti, A.1    Zallone, A.2
  • 194
    • 50249088828 scopus 로고    scopus 로고
    • Clinical outcomes with bioactive agents alone or in combination with grafting or guided tissue regeneration
    • Trombelli L., Farina R. (2008). Clinical outcomes with bioactive agents alone or in combination with grafting or guided tissue regeneration. J Clin Periodontol 35 (8 Suppl). 117S - 135S.
    • (2008) J Clin Periodontol , vol.35 , Issue.8
    • Trombelli, L.1    Farina, R.2
  • 196
    • 0035893281 scopus 로고    scopus 로고
    • Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro
    • Tutter AV, Fryer CJ, Jones KA (2001). Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro. Genes Dev 15: 3342-3354.
    • (2001) Genes Dev , vol.15 , pp. 3342-3354
    • Tutter, A.V.1    Fryer, C.J.2    Jones, K.A.3
  • 198
    • 55749102279 scopus 로고    scopus 로고
    • Alternative wnt signaling is initiated by distinct receptors
    • van Amerongen R., Mikels A., Nusse R. (2008). Alternative wnt signaling is initiated by distinct receptors. Sci Signal 1 (35). re9.
    • (2008) Sci Signal , vol.1 , Issue.35 , pp. 9
    • Van Amerongen, R.1    Mikels, A.2    Nusse, R.3
  • 199
    • 12144286871 scopus 로고    scopus 로고
    • Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist
    • van Bezooijen RL, Roelen BA, Visser A., van der Wee-Pals L., de Wilt E., Karperien M., et al. (2004). Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist. J Exp Med 199: 805-814.
    • (2004) J Exp Med , vol.199 , pp. 805-814
    • Van Bezooijen, R.L.1    Roelen, B.A.2    Visser, A.3    Van Der Wee-Pals, L.4    De Wilt, E.5    Karperien, M.6
  • 202
    • 25444433584 scopus 로고    scopus 로고
    • Downregulation of Wnt signaling by increased expression of Dickkopf-1 and -2 is a prerequisite for late-stage osteoblast differentiation of KS483 cells
    • van der Horst G., van der Werf SM, Farih-Sips H., van Bezooijen RL, Lowik CW, Karperien M. (2005). Downregulation of Wnt signaling by increased expression of Dickkopf-1 and -2 is a prerequisite for late-stage osteoblast differentiation of KS483 cells. J Bone Miner Res 20: 1867-1877.
    • (2005) J Bone Miner Res , vol.20 , pp. 1867-1877
    • Van Der Horst, G.1    Van Der Werf, S.M.2    Farih-Sips, H.3    Van Bezooijen, R.L.4    Lowik, C.W.5    Karperien, M.6
  • 203
    • 0027945654 scopus 로고
    • Development of several organs that require inductive epithelial- mesenchymal interactions is impaired in LEF-1-deficient mice
    • van Genderen C., Okamura RM, Farinas I., Quo RG, Parslow TG, Bruhn L., et al. (1994). Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev 8: 2691-2703.
    • (1994) Genes Dev , vol.8 , pp. 2691-2703
    • Van Genderen, C.1    Okamura, R.M.2    Farinas, I.3    Quo, R.G.4    Parslow, T.G.5    Bruhn, L.6
  • 204
    • 67649441082 scopus 로고    scopus 로고
    • Osteocyte morphology in human tibiae of different bone pathologies with different bone mineral density-is there a role for mechanosensing?
    • van Hove RP, Nolte PA, Vatsa A., Semeins CM, Salmon PL, Smit TH, et al. (2009). Osteocyte morphology in human tibiae of different bone pathologies with different bone mineral density-is there a role for mechanosensing? Bone 45: 321-329.
    • (2009) Bone , vol.45 , pp. 321-329
    • Van Hove, R.P.1    Nolte, P.A.2    Vatsa, A.3    Semeins, C.M.4    Salmon, P.L.5    Smit, T.H.6
  • 205
  • 206
    • 73949093736 scopus 로고    scopus 로고
    • Regulation of Wnt/beta-catenin signaling by protein kinases
    • Verheyen EM, Gottardi CJ (2009). Regulation of Wnt/beta-catenin signaling by protein kinases Dev Dyn 239: 34-44.
    • (2009) Dev Dyn , vol.239 , pp. 34-44
    • Verheyen, E.M.1    Gottardi, C.J.2
  • 207
    • 67449092566 scopus 로고    scopus 로고
    • Characterization of the structural features and interactions of sclerostin: Molecular insight into a key regulator of Wnt-mediated bone formation
    • Veverka V., Henry AJ, Slocombe PM, Ventom A., Mulloy B., Muskett FW, et al. (2009). Characterization of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation. J Biol Chem 284: 10890-10900.
    • (2009) J Biol Chem , vol.284 , pp. 10890-10900
    • Veverka, V.1    Henry, A.J.2    Slocombe, P.M.3    Ventom, A.4    Mulloy, B.5    Muskett, F.W.6
  • 208
    • 0028342810 scopus 로고
    • Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension
    • Wang N., Ingber DE (1994). Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension. Biophys J 66: 2181-2189.
    • (1994) Biophys J , vol.66 , pp. 2181-2189
    • Wang, N.1    Ingber, D.E.2
  • 209
    • 0027172919 scopus 로고
    • Mechanotransduction across the cell surface and through the cytoskeleton
    • Wang N., Butler JP, Ingber DE (1993). Mechanotransduction across the cell surface and through the cytoskeleton. Science 260: 1124-1127.
    • (1993) Science , vol.260 , pp. 1124-1127
    • Wang, N.1    Butler, J.P.2    Ingber, D.E.3
  • 211
    • 58049211966 scopus 로고    scopus 로고
    • Mechanotransduction at a distance: Mechanically coupling the extracellular matrix with the nucleus
    • Wang N., Tytell JD, Ingber DE (2009). Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol 10: 75-82.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 75-82
    • Wang, N.1    Tytell, J.D.2    Ingber, D.E.3
  • 213
    • 0027697096 scopus 로고
    • Ectopic bone induction by human fetal enamel proteins
    • Wang W. (1993). Ectopic bone induction by human fetal enamel proteins. Zhonghua Kou Qiang Yi Xue Za Zhi 28: 362-364, 384.
    • (1993) Zhonghua Kou Qiang Yi Xue Za Zhi , vol.28 , pp. 362-364
    • Wang, W.1
  • 214
    • 69549134095 scopus 로고    scopus 로고
    • Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood
    • Wang XP, OConnell DJ, Lund JJ, Saadi I., Kuraguchi M., Turbe-Doan A., et al. (2009). Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood. Development 136: 1939-1949.
    • (2009) Development , vol.136 , pp. 1939-1949
    • Wang, X.P.1    Oconnell, D.J.2    Lund, J.J.3    Saadi, I.4    Kuraguchi, M.5    Turbe-Doan, A.6
  • 215
    • 34249913494 scopus 로고    scopus 로고
    • The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development
    • Wang Y., Wan C., Deng L., Liu X., Cao X., Gilbert SR, et al. (2007). The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest 117: 1616-1626.
    • (2007) J Clin Invest , vol.117 , pp. 1616-1626
    • Wang, Y.1    Wan, C.2    Deng, L.3    Liu, X.4    Cao, X.5    Gilbert, S.R.6
  • 216
    • 33646549601 scopus 로고    scopus 로고
    • Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells
    • Watanabe S., Umehara H., Murayama K., Okabe M., Kimura T., Nakano T. (2006). Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells. Oncogene 25: 2697-2707.
    • (2006) Oncogene , vol.25 , pp. 2697-2707
    • Watanabe, S.1    Umehara, H.2    Murayama, K.3    Okabe, M.4    Kimura, T.5    Nakano, T.6
  • 218
    • 77949587011 scopus 로고    scopus 로고
    • Glucocorticoids, osteocytes, and skeletal fragility: The role of bone vascularity
    • Weinstein RS (2009). Glucocorticoids, osteocytes, and skeletal fragility: the role of bone vascularity. Bone [Epub ahead of print] June 9, 2009 (in press).
    • (2009) Bone
    • Weinstein, R.S.1
  • 219
    • 0034456539 scopus 로고    scopus 로고
    • Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hip
    • Weinstein RS, Nicholas RW, Manolagas SC (2000). Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hip. J Clin Endocrinol Metab 85: 2907-2912.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2907-2912
    • Weinstein, R.S.1    Nicholas, R.W.2    Manolagas, S.C.3
  • 220
    • 0036365939 scopus 로고    scopus 로고
    • Some effects of enamel matrix proteins on wound healing in the dento-gingival region
    • Wennstrm JL, Lindhe J. (2002). Some effects of enamel matrix proteins on wound healing in the dento-gingival region. J Clin Periodontol 29: 9-14.
    • (2002) J Clin Periodontol , vol.29 , pp. 9-14
    • Wennstrm, J.L.1    Lindhe, J.2
  • 221
    • 0037229938 scopus 로고    scopus 로고
    • Runnin with the Dvl: Proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction
    • Wharton KA Jr (2003). Runnin with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction. Dev Biol 253: 1-17.
    • (2003) Dev Biol , vol.253 , pp. 1-17
    • Wharton Jr., K.A.1
  • 222
    • 0038034405 scopus 로고    scopus 로고
    • Primary cilium-is it an osteocytes strain-sensing flowmeter
    • Whitfield JF (2003). Primary cilium-is it an osteocytes strain-sensing flowmeter ? J Cell Biochem 89: 233-237.
    • (2003) J Cell Biochem , vol.89 , pp. 233-237
    • Whitfield, J.F.1
  • 223
    • 70350337082 scopus 로고    scopus 로고
    • Bone morphogenetic proteins for periodontal and alveolar indications; Biological observations-clinical implications
    • Wikesj UM, Qahash M., Huang YH, Xiropaidis A., Polimeni G., Susin C. (2009). Bone morphogenetic proteins for periodontal and alveolar indications; biological observations-clinical implications Orthod Craniofac Res 12: 263-270.
    • (2009) Orthod Craniofac Res , vol.12 , pp. 263-270
    • Wikesj, U.M.1    Qahash, M.2    Huang, Y.H.3    Xiropaidis, A.4    Polimeni, G.5    Susin, C.6
  • 225
    • 0033251930 scopus 로고    scopus 로고
    • Lack of integration of smooth titanium surfaces: A working hypothesis based on strains generated in the surrounding bone
    • Wiskott HW, Belser UC (1999). Lack of integration of smooth titanium surfaces: a working hypothesis based on strains generated in the surrounding bone. Clin Oral Implants Res 10: 429-444.
    • (1999) Clin Oral Implants Res , vol.10 , pp. 429-444
    • Wiskott, H.W.1    Belser, U.C.2
  • 226
    • 58049220350 scopus 로고    scopus 로고
    • Mechanotransduction in development: A growing role for contractility
    • Wozniak MA, Chen CS (2009). Mechanotransduction in development: a growing role for contractility. Nat Rev Mol Cell Biol 10: 34-43.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 34-43
    • Wozniak, M.A.1    Chen, C.S.2
  • 227
    • 35648965654 scopus 로고    scopus 로고
    • Mechanistic insights from structural studies of beta-catenin and its binding partners
    • Xu W., Kimelman D. (2007). Mechanistic insights from structural studies of beta-catenin and its binding partners. J Cell Sci 120 (Pt 19). 3337-3344.
    • (2007) J Cell Sci , vol.120 , Issue.19 , pp. 3337-3344
    • Xu, W.1    Kimelman, D.2
  • 228
    • 33746482870 scopus 로고    scopus 로고
    • Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin
    • Yamamoto H., Komekado H., Kikuchi A. (2006). Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. Dev Cell 11: 213-223.
    • (2006) Dev Cell , vol.11 , pp. 213-223
    • Yamamoto, H.1    Komekado, H.2    Kikuchi, A.3
  • 229
    • 46049089076 scopus 로고    scopus 로고
    • Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling
    • Yamamoto H., Sakane H., Michiue T., Kikuchi A. (2008). Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling. Dev Cell 15: 37-48.
    • (2008) Dev Cell , vol.15 , pp. 37-48
    • Yamamoto, H.1    Sakane, H.2    Michiue, T.3    Kikuchi, A.4
  • 230
    • 70350379620 scopus 로고    scopus 로고
    • Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice
    • Yan Y., Tang D., Chen M., Huang J., Xie R., Jonason JH, et al. (2009). Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice. J Cell Sci 122 (Pt 19). 3566-3578.
    • (2009) J Cell Sci , vol.122 , Issue.19 , pp. 3566-3578
    • Yan, Y.1    Tang, D.2    Chen, M.3    Huang, J.4    Xie, R.5    Jonason, J.H.6
  • 231
    • 0030265570 scopus 로고    scopus 로고
    • A frizzled homolog functions in a vertebrate Wnt signaling pathway
    • Yang-Snyder J., Miller JR, Brown JD, Lai CJ, Moon RT (1996). A frizzled homolog functions in a vertebrate Wnt signaling pathway. Curr Biol 6: 1302-1306.
    • (1996) Curr Biol , vol.6 , pp. 1302-1306
    • Yang-Snyder, J.1    Miller, J.R.2    Brown, J.D.3    Lai, C.J.4    Moon, R.T.5
  • 232
  • 233
    • 0038782306 scopus 로고    scopus 로고
    • Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth
    • Yu K., Xu J., Liu Z., Sosic D., Shao J., Olson EN, et al. (2003). Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development 130: 3063-3074.
    • (2003) Development , vol.130 , pp. 3063-3074
    • Yu, K.1    Xu, J.2    Liu, Z.3    Sosic, D.4    Shao, J.5    Olson, E.N.6
  • 234
    • 67649528327 scopus 로고    scopus 로고
    • Interaction between PGE2 and EGF receptor through MAPKs in mouse embryonic stem cell proliferation
    • Yun SP, Lee MY, Ryu JM, Han HJ (2009). Interaction between PGE2 and EGF receptor through MAPKs in mouse embryonic stem cell proliferation. Cell Mol Life Sci 66: 1603-1616.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 1603-1616
    • Yun, S.P.1    Lee, M.Y.2    Ryu, J.M.3
  • 235
    • 38949194936 scopus 로고    scopus 로고
    • Initiation of Wnt signaling: Control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
    • Zeng X., Huang H., Tamai K., Zhang X., Harada Y., Yokota C., et al. (2008). Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development 135: 367-375.
    • (2008) Development , vol.135 , pp. 367-375
    • Zeng, X.1    Huang, H.2    Tamai, K.3    Zhang, X.4    Harada, Y.5    Yokota, C.6
  • 236
    • 44349125905 scopus 로고    scopus 로고
    • Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix
    • Zhang C., Cho K., Huang Y., Lyons JP, Zhou X., Sinha K., et al. (2008). Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix. Proc Natl Acad Sci USA 105: 6936-6941.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6936-6941
    • Zhang, C.1    Cho, K.2    Huang, Y.3    Lyons, J.P.4    Zhou, X.5    Sinha, K.6
  • 237
    • 43149106504 scopus 로고    scopus 로고
    • Wdr5 is essential for osteoblast differentiation
    • Zhu ED, Demay MB, Gori F. (2008). Wdr5 is essential for osteoblast differentiation. J Biol Chem 283: 7361-7367.
    • (2008) J Biol Chem , vol.283 , pp. 7361-7367
    • Zhu, E.D.1    Demay, M.B.2    Gori, F.3
  • 238
    • 33846327243 scopus 로고    scopus 로고
    • Differential requirement of MKK4 and MKK7 in JNK activation by distinct scaffold proteins
    • Zou H., Li Q., Lin SC, Wu Z., Han J., Ye Z. (2007). Differential requirement of MKK4 and MKK7 in JNK activation by distinct scaffold proteins. FEBS Lett 581: 196-202.
    • (2007) FEBS Lett , vol.581 , pp. 196-202
    • Zou, H.1    Li, Q.2    Lin, S.C.3    Wu, Z.4    Han, J.5    Ye, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.