The relation of femoral osteon geometry to age, sex, height and weight

Bone

Volumn 45, Issue 1, 2009, Pages 77-83

  Britz, Hayley M ^a   Thomas, C David L ^b   Clement, John G ^b   Cooper, David M L ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Cortical bone; Haversian system; Histomorphometry; Osteon; Remodeling

Indexed keywords

ADOLESCENT; ADULT; AGE; AGED; ARTICLE; BODY HEIGHT; BODY WEIGHT; BONE REMODELING; BONE STRUCTURE; CADAVER; CONTROLLED STUDY; CORTICAL BONE; FEMALE; FEMUR; HAVERSIAN CANAL; HUMAN; MALE; OSTEOMETRY; SEX DIFFERENCE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; ANTHROPOMETRY; BODY HEIGHT; BODY WEIGHT; FEMALE; FEMUR; HAVERSIAN SYSTEM; HUMANS; MALE; MIDDLE AGED; REGRESSION ANALYSIS; SEX CHARACTERISTICS;

EID: 67349265175     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.03.654     Document Type: Article

References (68)

1. Skedros J.G., Mason M.W., and Bloebaum R.D. Differences in osteonal micromorphology between tensile and compressive cortices of a bending skeletal system: indications of potential strain-specific differences in bone microstructure. Anat. Rec. 239 (1994) 405-413
2. Pfeiffer S. Variability in osteon size in recent human populations. Am. J. Phys. Anthropol. 106 (1998) 219-227
3. Currey J.D. Some effects of ageing in human Haversian systems. J. Anat. 98 (1964) 69-75
4. Baca V., Kachlik D., Horak Z., and Stingl J. The course of osteons in the compact bone of the human proximal femur with clinical and biomechanical significance. Surg. Radiol. Anat. 29 (2007) 201-207
5. Hert J., Fiala P., and Petrtyl M. Osteon orientation of the diaphysis of the long bones in man. Bone 15 (1994) 269-277
6. Petrtyl M., Hert J., and Fiala P. Spatial organization of the Haversian bone in man. J. Biomech. 29 (1996) 161-169
7. Burger E.H., Klein-Nulend J., and Smit T.H. Strain-derived canalicular fluid flow regulates osteoclast activity in a remodelling osteon-a proposal. J. Biomech. 36 (2003) 1453-1459
8. Smit T.H., and Burger E.H. Is BMU-coupling a strain-regulated phenomenon? A finite element analysis. J. Bone Miner. Res. 15 (2000) 301-307
9. Smit T.H., Burger E.H., and Huyghe J.M. A case for strain-induced fluid flow as a regulator of BMU-coupling and osteonal alignment. J. Bone Miner. Res. 17 (2002) 2021-2029
10. van Oers R.F., Ruimerman R., Tanck E., Hilbers P.A., and Huiskes R. A unified theory for osteonal and hemi-osteonal remodeling. Bone 42 (2008) 250-259
11. van Oers R.F., Ruimerman R., van Rietbergen B., Hilbers P.A., and Huiskes R. Relating osteon diameter to strain. Bone 43 (2008) 476-482
12. Skedros J.G., Mason M.W., and Bloebaum R.D. Modeling and remodeling in a developing artiodactyl calcaneus: a model for evaluating Frost's Mechanostat hypothesis and its corollaries. Anat. Rec. 263 (2001) 167-185
13. Skedros J.G., Su S.C., and Bloebaum R.D. Biomechanical implications of mineral content and microstructural variations in cortical bone of horse, elk, and sheep calcanei. Anat. Rec. 249 (1997) 297-316
14. Young D.R., Niklowitz W.J., Brown R.J., and Jee W.S. Immobilization-associated osteoporosis in primates. Bone 7 (1986) 109-117
15. Watanabe Y., Konishi M., Shimada M., Ohara H., and Iwamoto S. Estimation of age from the femur of Japanese cadavers. Forensic Sci. Int. 98 (1998) 55-65
16. Evans F.G. Mechanical properties and histology of cortical bone from younger and older men. Anat. Rec. 185 (1976) 1-11
17. Burr D.B., Ruff C.B., and Thompson D.D. Patterns of skeletal histologic change through time: comparison of an archaic native American population with modern populations. Anat. Rec. 226 (1990) 307-313
18. Ericksen M.F. Histologic estimation of age at death using the anterior cortex of the femur. Am. J. Phys. Anthropol. 84 (1991) 171-179
19. Iwamoto S., Oonuki E., and Konishi M. Study on the age-related changes of the compact bone and the age estimation: 2. On the humerus. Acta med. Kinki Univ. 3 (1978) 203-208
20. Jowsey J. Age and species differences in bone. Cornell Vet. 58 (1968) 74-94
21. Kerley E.R. The microscopic determination of age in human bone. Am. J. Phys. Anthropol. 23 (1965) 149-163
22. Ortner D.J. Aging effects on osteon remodeling. Calcif. Tissue Res. 18 (1975) 27-36
23. Singh I.J., and Gunberg D.L. Estimation of age at death in human males from quantitative histology of bone fragments. Am. J. Phys. Anthropol. 33 (1970) 373-381
24. Thompson D.D., and Galvin C.A. Estimation of age at death by tibial osteon remodeling in an autopsy series. Forensic Sci. Int. 22 (1983) 203-211
25. Ural A., and Vashishth D. Interactions between microstructural and geometrical adaptation in human cortical bone. J. Orthop. Res. 24 (2006) 1489-1498
26. Wegmann A. Die alters-und geschlechtsunterschiede des knochenanbaus in rippenkortikalis und beckenkammaspongiosa. Acta Anat. 84 (1973) 572-583
27. Yoshino M., Imaizumi K., Miyasaka S., and Seta S. Histological estimation of age at death using microradiographs of humeral compact bone. Forensic Sci. Int. 64 (1994) 191-198
28. Hattner R., Landeros O., and Frost H.M. Are there cell behavioral modes that are unaffected by aging?. Gerontology 4 (1964)
29. Martin R.B., Pickett J.C., and Zinaich S. Studies of skeletal remodeling in aging men. Clin. Orthop. Relat. Res. (1980) 268-282
30. Havill L.M. Osteon remodeling dynamics in Macaca mulatta: normal variation with regard to age, sex, and skeletal maturity. Calcif. Tissue Int. 74 (2004) 95-102
31. Burr D.B. Estimated intracortical bone turnover in the femur of growing macaques: implications for their use as models in skeletal pathology. Anat. Rec. 232 (1992) 180-189
32. Singh I.J., and Gunberg D.L. Quantitative histology of changes with age in rat bone cortex. J. Morphol. 133 (1971) 241-251
33. Pearson O.M., Lieberman D.E., and The aging o.f. Wolff's "law": ontogeny and responses to mechanical loading in cortical bone. Am. J. Phys. Anthropol. Suppl 39 (2004) 63-99
34. Kohrt W.M. Aging and the osteogenic response to mechanical loading. Int. J. Sport Nutr. Exerc. Metab. 11 Suppl (2001) S137-S142
35. Moyle D.D., Welborn III J.W., and Cooke F.W. Work to fracture of canine femoral bone. J. Biomech. 11 (1978) 435-440
36. Moyle D.D., and Bowden R.W. Fracture of human femoral bone. J. Biomech. 17 (1984) 203-213
37. Takahashi H., Epker B., and Frost H.M. Relation between age and size of osteons in man. Henry Ford Hosp. Med. Bull. 13 (1965) 25-31
38. Bell K.L., Loveridge N., Reeve J., Thomas C.D., Feik S.A., and Clement J.G. Super-osteons (remodeling clusters) in the cortex of the femoral shaft: influence of age and gender. Anat. Rec. 264 (2001) 378-386
39. Black J., Mattson R., and Korostoff E. Haversian osteons: size, distribution, internal structure, and orientation. J. Biomed. Mater. Res. 8 (1974) 299-319
40. Jowsey J. Studies of Haversian systems in man and some animals. J. Anat. 100 (1966) 857-864
41. Mulhern D.M., and Van Gerven D.P. Patterns of femoral bone remodeling dynamics in a Medieval Nubian population. Am. J. Phys. Anthropol. 104 (1997) 133-146
42. Pfeiffer S., Crowder C., Harrington L., and Brown M. Secondary osteon and Haversian canal dimensions as behavioral indicators. Am. J. Phys. Anthropol. 131 (2006) 460-468
43. Cooper D.M., Thomas C.D., Clement J.G., Turinsky A.L., Sensen C.W., and Hallgrimsson B. Age-dependent change in the 3D structure of cortical porosity at the human femoral midshaft. Bone 40 (2007) 957-965
44. Clement J.G. The Melbourne Femur Collection: the gift of tissue underpins important medical and forensic research. VIFM Review 3 (2005) 7-11
45. Thomas C.D., Feik S.A., and Clement J.G. Regional variation of intracortical porosity in the midshaft of the human femur: age and sex differences. J. Anat. 206 (2005) 115-125
46. Robling A.G., and Stout S.D. Histomorphometry of human cortical bone. In: Katzenberg M.A., and Saunders S.A. (Eds). Biological Anthropology of the Human Skeleton (2000), John Wiley and Sons, Inc., Toronto 187-213
47. Szivek J.A., Benjamin J.B., and Anderson P.L. An experimental method for the application of lateral muscle loading and its effect on femoral strain distributions. Med. Eng. Phys. 22 (2000) 109-116
48. Rubin C.T., and Lanyon L.E. Limb mechanics as a function of speed and gait: a study of functional strains in the radius and tibia of horse and dog. J. Exp. Biol. 101 (1982) 187-211
49. Gibson V.A., Stover S.M., Gibeling J.C., Hazelwood S.J., and Martin R.B. Osteonal effects on elastic modulus and fatigue life in equine bone. J. Biomech. 39 (2006) 217-225
50. Goulet G.C., Cooper D.M., Coombe D., and Zernicke R.F. Influence of cortical canal architecture on lacunocanalicular pore pressure and fluid flow. Comput. Methods Biomech. Biomed. Engin. 11 (2008) 379-387
51. Abbott S., Trinkaus E., and Burr D.B. Dynamic bone remodeling in later Pleistocene fossil hominids. Am. J. Phys. Anthropol. 99 (1996) 585-601
52. Martin R.K., Albright J.P., Clarke W.R., and Niffenegger J.A. Load-carrying effects on the adult beagle tibia. Med. Sci. Sports Exerc. 13 (1981) 343-349
53. van der Wiel H.E., Lips P., Graafmans W.C., Danielsen C.C., Nauta J., van Lingen A., et al. Additional weight-bearing during exercise is more important than duration of exercise for anabolic stimulus of bone: a study of running exercise in female rats. Bone 16 (1995) 73-80
54. Tromp A.M., Bravenboer N., Tanck E., Oostlander A., Holzmann P.J., Kostense P.J., et al. Additional weight bearing during exercise and estrogen in the rat: the effect on bone mass, turnover, and structure. Calcif. Tissue Int. 79 (2006) 404-415
55. Gomez-Ambrosi J., Rodriguez A., Catalan V., and Fruhbeck G. The bone-adipose axis in obesity and weight loss. Obes. Surg. 18 (2008) 1134-1143
56. Reid I.R. Relationships among body mass, its components, and bone. Bone 31 (2002) 547-555
57. Tappen N.C. Three-dimensional studies on resorption spaces and developing osteons. Am. J. Anat. 149 (1977) 301-317
58. Hiller L.P., Stover S.M., Gibson V.A., Gibeling J.C., Prater C.S., Hazelwood S.J., et al. Osteon pullout in the equine third metacarpal bone: effects of ex vivo fatigue. J. Orthop. Res. 21 (2003) 481-488
59. Martin R.B., Gibson V.A., Stover S.M., Gibeling J.C., and Griffin L.V. Osteonal structure in the equine third metacarpus. Bone 19 (1996) 165-171
60. Yeni Y.N., Brown C.U., Wang Z., and Norman T.L. The influence of bone morphology on fracture toughness of the human femur and tibia. Bone 21 (1997) 453-459
61. O'Brien F.J., Taylor D., and Clive Lee T. The effect of bone microstructure on the initiation and growth of microcracks. J. Orthop. Res. 23 (2005) 475-480
62. Villareal D.T., Shah K., Banks M.R., Sinacore D.R., and Klein S. Effect of weight loss and exercise therapy on bone metabolism and mass in obese older adults: a one-year randomized controlled trial. J. Clin. Endocrinol. Metab. 93 (2008) 2181-2187
63. Papaioannou A., Kennedy C.C., Cranney A., Hawker G., Brown J.P., Kaiser S.M., et al. Risk factors for low BMD in healthy men age 50 years or older: a systematic review. Osteoporos. Int. (2008)
64. Power J., Loveridge N., Lyon A., Rushton N., Parker M., and Reeve J. Osteoclastic cortical erosion as a determinant of subperiosteal osteoblastic bone formation in the femoral neck's response to BMU imbalance. Effects of stance-related loading and hip fracture. Osteoporos. Int. 16 (2005) 1049-1056
65. Kaptoge S., Dalzell N., Loveridge N., Beck T.J., Khaw K.T., and Reeve J. Effects of gender, anthropometric variables, and aging on the evolution of hip strength in men and women aged over 65. Bone 32 (2003) 561-570
66. Russo C.R., Lauretani F., Seeman E., Bartali B., Bandinelli S., Di Iorio A., et al. Structural adaptations to bone loss in aging men and women. Bone 38 (2006) 112-118
67. Cooper D.M., Thomas C.D., Clement J.G., and Hallgrimsson B. Three-dimensional microcomputed tomography imaging of basic multicellular unit-related resorption spaces in human cortical bone. Anat. Rec. A. Discov. Mol. Cell. Evol. Biol. 288 (2006) 806-816
68. Thomas C.D., Cooper D.M., Clement J.G., Peele A.G., and Hanah K. Intra-osteon distribution of osteocyte lacunae in human cortical bone assessed by synchrotron radiation micro-CT. Aust. Phys. Eng. Sci. Med. 30 (2007) 433