메뉴 건너뛰기




Volumn 5, Issue 6, 2007, Pages 464-475

Targeted Ablation of Osteocytes Induces Osteoporosis with Defective Mechanotransduction

Author keywords

HUMDISEASE

Indexed keywords

DIPHTHERIA TOXIN; RECEPTOR;

EID: 34249657953     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2007.05.001     Document Type: Article
Times cited : (701)

References (47)
  • 2
    • 0344450755 scopus 로고    scopus 로고
    • Vitamin D3 differentially regulates parathyroid hormone/parathyroid hormone-related peptide receptor expression in bone and cartilage
    • Amizuka N., Kwan M.Y., Goltzman D., Ozawa H., and White J.H. Vitamin D3 differentially regulates parathyroid hormone/parathyroid hormone-related peptide receptor expression in bone and cartilage. J. Clin. Invest. 103 (1999) 373-381
    • (1999) J. Clin. Invest. , vol.103 , pp. 373-381
    • Amizuka, N.1    Kwan, M.Y.2    Goltzman, D.3    Ozawa, H.4    White, J.H.5
  • 4
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle W.J., Simonet W.S., and Lacey D.L. Osteoclast differentiation and activation. Nature 423 (2003) 337-342
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 5
    • 0033233166 scopus 로고    scopus 로고
    • Growing C57Bl/6 mice increase whole bone mechanical properties by increasing geometric and material properties
    • Brodt M.D., Ellis C.B., and Silva M.J. Growing C57Bl/6 mice increase whole bone mechanical properties by increasing geometric and material properties. J. Bone Miner. Res. 14 (1999) 2159-2166
    • (1999) J. Bone Miner. Res. , vol.14 , pp. 2159-2166
    • Brodt, M.D.1    Ellis, C.B.2    Silva, M.J.3
  • 6
    • 0032895922 scopus 로고    scopus 로고
    • Mechanotransduction in bone--role of the lacuno-canalicular network
    • Burger E.H., and Klein-Nulend J. Mechanotransduction in bone--role of the lacuno-canalicular network. FASEB J. 13 Suppl (1999) S101-S112
    • (1999) FASEB J. , vol.13 , Issue.SUPPL
    • Burger, E.H.1    Klein-Nulend, J.2
  • 7
    • 0034285013 scopus 로고    scopus 로고
    • The osteoblast: a sophisticated fibroblast under central surveillance
    • Ducy P., Schinke T., and Karsenty G. The osteoblast: a sophisticated fibroblast under central surveillance. Science 289 (2000) 1501-1504
    • (2000) Science , vol.289 , pp. 1501-1504
    • Ducy, P.1    Schinke, T.2    Karsenty, G.3
  • 8
    • 0036712047 scopus 로고    scopus 로고
    • Mechanical strain and bone cell function: a review
    • Ehrlich P.J., and Lanyon L.E. Mechanical strain and bone cell function: a review. Osteoporos. Int. 13 (2002) 688-700
    • (2002) Osteoporos. Int. , vol.13 , pp. 688-700
    • Ehrlich, P.J.1    Lanyon, L.E.2
  • 9
    • 33750454816 scopus 로고    scopus 로고
    • Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism
    • Feng J.Q., Ward L.M., Liu S., Lu Y., Xie Y., Yuan B., Yu X., Rauch F., Davis S.I., Zhang S., et al. Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat. Genet. 38 (2006) 1310-1315
    • (2006) Nat. Genet. , vol.38 , pp. 1310-1315
    • Feng, J.Q.1    Ward, L.M.2    Liu, S.3    Lu, Y.4    Xie, Y.5    Yuan, B.6    Yu, X.7    Rauch, F.8    Davis, S.I.9    Zhang, S.10
  • 10
    • 33644975844 scopus 로고    scopus 로고
    • Buried alive: how osteoblasts become osteocytes
    • Franz-Odendaal T.A., Hall B.K., and Witten P.E. Buried alive: how osteoblasts become osteocytes. Dev. Dyn. 235 (2006) 176-190
    • (2006) Dev. Dyn. , vol.235 , pp. 176-190
    • Franz-Odendaal, T.A.1    Hall, B.K.2    Witten, P.E.3
  • 11
    • 0027302406 scopus 로고
    • Characterization of a novel dentin matrix acidic phosphoprotein. Implications for induction of biomineralization
    • George A., Sabsay B., Simonian P.A., and Veis A. Characterization of a novel dentin matrix acidic phosphoprotein. Implications for induction of biomineralization. J. Biol. Chem. 268 (1993) 12624-12630
    • (1993) J. Biol. Chem. , vol.268 , pp. 12624-12630
    • George, A.1    Sabsay, B.2    Simonian, P.A.3    Veis, A.4
  • 12
    • 0021267476 scopus 로고
    • Effects of simulated weightlessness on bone mineral metabolism
    • Globus R.K., Bikle D.D., and Morey-Holton E. Effects of simulated weightlessness on bone mineral metabolism. Endocrinology 114 (1984) 2264-2270
    • (1984) Endocrinology , vol.114 , pp. 2264-2270
    • Globus, R.K.1    Bikle, D.D.2    Morey-Holton, E.3
  • 13
    • 0037673933 scopus 로고    scopus 로고
    • Control of osteoblast function and regulation of bone mass
    • Harada S., and Rodan G.A. Control of osteoblast function and regulation of bone mass. Nature 423 (2003) 349-355
    • (2003) Nature , vol.423 , pp. 349-355
    • Harada, S.1    Rodan, G.A.2
  • 14
    • 25444529444 scopus 로고    scopus 로고
    • Multi-detector row CT imaging of vertebral microstructure for evaluation of fracture risk
    • Ito M., Ikeda K., Nishiguchi M., Shindo H., Uetani M., Hosoi T., and Orimo H. Multi-detector row CT imaging of vertebral microstructure for evaluation of fracture risk. J. Bone Miner. Res. 20 (2005) 1828-1836
    • (2005) J. Bone Miner. Res. , vol.20 , pp. 1828-1836
    • Ito, M.1    Ikeda, K.2    Nishiguchi, M.3    Shindo, H.4    Uetani, M.5    Hosoi, T.6    Orimo, H.7
  • 15
    • 2942750269 scopus 로고    scopus 로고
    • Dentin matrix protein 1 expression during osteoblastic differentiation, generation of an osteocyte GFP-transgene
    • Kalajzic I., Braut A., Guo D., Jiang X., Kronenberg M.S., Mina M., Harris M.A., Harris S.E., and Rowe D.W. Dentin matrix protein 1 expression during osteoblastic differentiation, generation of an osteocyte GFP-transgene. Bone 35 (2004) 74-82
    • (2004) Bone , vol.35 , pp. 74-82
    • Kalajzic, I.1    Braut, A.2    Guo, D.3    Jiang, X.4    Kronenberg, M.S.5    Mina, M.6    Harris, M.A.7    Harris, S.E.8    Rowe, D.W.9
  • 16
    • 0035130601 scopus 로고    scopus 로고
    • A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy
    • Kamioka H., Honjo T., and Takano-Yamamoto T. A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy. Bone 28 (2001) 145-149
    • (2001) Bone , vol.28 , pp. 145-149
    • Kamioka, H.1    Honjo, T.2    Takano-Yamamoto, T.3
  • 17
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • Karsenty G., and Wagner E.F. Reaching a genetic and molecular understanding of skeletal development. Dev. Cell 2 (2002) 389-406
    • (2002) Dev. Cell , vol.2 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 20
    • 28144464147 scopus 로고    scopus 로고
    • DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis
    • Ling Y., Rios H.F., Myers E.R., Lu Y., Feng J.Q., and Boskey A.L. DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis. J. Bone Miner. Res. 20 (2005) 2169-2177
    • (2005) J. Bone Miner. Res. , vol.20 , pp. 2169-2177
    • Ling, Y.1    Rios, H.F.2    Myers, E.R.3    Lu, Y.4    Feng, J.Q.5    Boskey, A.L.6
  • 22
    • 0028925088 scopus 로고
    • Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis
    • Manolagas S.C., and Jilka R.L. Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis. N. Engl. J. Med. 332 (1995) 305-311
    • (1995) N. Engl. J. Med. , vol.332 , pp. 305-311
    • Manolagas, S.C.1    Jilka, R.L.2
  • 23
    • 13244267455 scopus 로고    scopus 로고
    • Osteoclast-derived activity in the coupling of bone formation to resorption
    • Martin T.J., and Sims N.A. Osteoclast-derived activity in the coupling of bone formation to resorption. Trends Mol. Med. 11 (2005) 76-81
    • (2005) Trends Mol. Med. , vol.11 , pp. 76-81
    • Martin, T.J.1    Sims, N.A.2
  • 24
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
    • Nakashima K., Zhou X., Kunkel G., Zhang Z., Deng J.M., Behringer R.R., and de Crombrugghe B. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108 (2002) 17-29
    • (2002) Cell , vol.108 , pp. 17-29
    • Nakashima, K.1    Zhou, X.2    Kunkel, G.3    Zhang, Z.4    Deng, J.M.5    Behringer, R.R.6    de Crombrugghe, B.7
  • 25
    • 0029783770 scopus 로고    scopus 로고
    • Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis
    • Pacifici R. Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis. J. Bone Miner. Res. 11 (1996) 1043-1051
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 1043-1051
    • Pacifici, R.1
  • 26
    • 0028362416 scopus 로고
    • Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone
    • Parfitt A.M. Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. J. Cell. Biochem. 55 (1994) 273-286
    • (1994) J. Cell. Biochem. , vol.55 , pp. 273-286
    • Parfitt, A.M.1
  • 27
    • 0036140080 scopus 로고    scopus 로고
    • Targeted and nontargeted bone remodeling: relationship to basic multicellular unit origination and progression
    • Parfitt A.M. Targeted and nontargeted bone remodeling: relationship to basic multicellular unit origination and progression. Bone 30 (2002) 5-7
    • (2002) Bone , vol.30 , pp. 5-7
    • Parfitt, A.M.1
  • 29
    • 0036020416 scopus 로고    scopus 로고
    • Age and distance from the surface but not menopause reduce osteocyte density in human cancellous bone
    • Qiu S., Rao D.S., Palnitkar S., and Parfitt A.M. Age and distance from the surface but not menopause reduce osteocyte density in human cancellous bone. Bone 31 (2002) 313-318
    • (2002) Bone , vol.31 , pp. 313-318
    • Qiu, S.1    Rao, D.S.2    Palnitkar, S.3    Parfitt, A.M.4
  • 30
    • 31044432767 scopus 로고    scopus 로고
    • Pathogenesis of osteoporosis: concepts, conflicts, and prospects
    • Raisz L.G. Pathogenesis of osteoporosis: concepts, conflicts, and prospects. J. Clin. Invest. 115 (2005) 3318-3325
    • (2005) J. Clin. Invest. , vol.115 , pp. 3318-3325
    • Raisz, L.G.1
  • 33
    • 33744992495 scopus 로고    scopus 로고
    • Osteoporosis
    • Sambrook P., and Cooper C. Osteoporosis. Lancet 367 (2006) 2010-2018
    • (2006) Lancet , vol.367 , pp. 2010-2018
    • Sambrook, P.1    Cooper, C.2
  • 34
    • 0037172407 scopus 로고    scopus 로고
    • Pathogenesis of bone fragility in women and men
    • Seeman E. Pathogenesis of bone fragility in women and men. Lancet 359 (2002) 1841-1850
    • (2002) Lancet , vol.359 , pp. 1841-1850
    • Seeman, E.1
  • 35
    • 33646889773 scopus 로고    scopus 로고
    • Bone quality--the material and structural basis of bone strength and fragility
    • Seeman E., and Delmas P.D. Bone quality--the material and structural basis of bone strength and fragility. N. Engl. J. Med. 354 (2006) 2250-2261
    • (2006) N. Engl. J. Med. , vol.354 , pp. 2250-2261
    • Seeman, E.1    Delmas, P.D.2
  • 40
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • Teitelbaum S.L., and Ross F.P. Genetic regulation of osteoclast development and function. Nat. Rev. Genet. 4 (2003) 638-649
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 41
    • 0030884639 scopus 로고    scopus 로고
    • The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone
    • Tomkinson A., Reeve J., Shaw R.W., and Noble B.S. The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone. J. Clin. Endocrinol. Metab. 82 (1997) 3128-3135
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 3128-3135
    • Tomkinson, A.1    Reeve, J.2    Shaw, R.W.3    Noble, B.S.4
  • 42
    • 0034773406 scopus 로고    scopus 로고
    • Dentin matrix protein 1 is predominantly expressed in chicken and rat osteocytes but not in osteoblasts
    • Toyosawa S., Shintani S., Fujiwara T., Ooshima T., Sato A., Ijuhin N., and Komori T. Dentin matrix protein 1 is predominantly expressed in chicken and rat osteocytes but not in osteoblasts. J. Bone Miner. Res. 16 (2001) 2017-2026
    • (2001) J. Bone Miner. Res. , vol.16 , pp. 2017-2026
    • Toyosawa, S.1    Shintani, S.2    Fujiwara, T.3    Ooshima, T.4    Sato, A.5    Ijuhin, N.6    Komori, T.7
  • 44
    • 0034456539 scopus 로고    scopus 로고
    • Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hip
    • Weinstein R.S., Nicholas R.W., and Manolagas S.C. Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hip. J. Clin. Endocrinol. Metab. 85 (2000) 2907-2912
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 2907-2912
    • Weinstein, R.S.1    Nicholas, R.W.2    Manolagas, S.C.3
  • 46
    • 20144378532 scopus 로고    scopus 로고
    • Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo
    • Yang W., Lu Y., Kalajzic I., Guo D., Harris M.A., Gluhak-Heinrich J., Kotha S., Bonewald L.F., Feng J.Q., Rowe D.W., et al. Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo. J. Biol. Chem. 280 (2005) 20680-20690
    • (2005) J. Biol. Chem. , vol.280 , pp. 20680-20690
    • Yang, W.1    Lu, Y.2    Kalajzic, I.3    Guo, D.4    Harris, M.A.5    Gluhak-Heinrich, J.6    Kotha, S.7    Bonewald, L.F.8    Feng, J.Q.9    Rowe, D.W.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.