메뉴 건너뛰기




Volumn 253, Issue 1, 2003, Pages 1-17

Runnin' with the Dvl: Proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction

Author keywords

Arm; Armadillo; Convergent extension; Dishevelled; Dsh; Dvl; Frizzled; Fz; Planar cell polarity; Tissue polarity; Wg; Wingless; Wnt; catenin

Indexed keywords

BETA ARRESTIN; BETA CATENIN; CASEIN KINASE I; CASEIN KINASE II; DISHEVELLED PROTEIN; NOTCH RECEPTOR; P21 ACTIVATED KINASE 1; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2C; PROTEIN DAAM1; PROTEIN DAPPER; PROTEIN DERIVATIVE; PROTEIN EPS8; PROTEIN FRAT; PROTEIN FRODO; PROTEIN GBP; PROTEIN IDAX; PROTEIN KINASE; PROTEIN MUSK; PROTEIN NKD; PROTEIN PAR 1; PROTEIN PK; PROTEIN PKM; PROTEIN SPLE; PROTEIN STBM; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 0037229938     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2002.0869     Document Type: Review
Times cited : (273)

References (183)
  • 1
    • 0030978351 scopus 로고    scopus 로고
    • β-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle, H., et al. (1997). β-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16, 3797-3804.
    • (1997) EMBO J. , vol.16 , pp. 3797-3804
    • Aberle, H.1
  • 2
    • 0036111153 scopus 로고    scopus 로고
    • Planar signaling and morphogenesis in Drosophila
    • Adler, P. N. (2002). Planar signaling and morphogenesis in Drosophila. Dev. Cell 2, 525-535.
    • (2002) Dev. Cell , vol.2 , pp. 525-535
    • Adler, P.N.1
  • 3
    • 0034705992 scopus 로고    scopus 로고
    • The domineering non-autonomy of frizzled and van Gogh clones in the Drosophila wing is a consequence of a disruption in local signaling
    • Adler, P. N., et al. (2000). The domineering non-autonomy of frizzled and van Gogh clones in the Drosophila wing is a consequence of a disruption in local signaling. Mech. Dev. 96, 197-207.
    • (2000) Mech. Dev. , vol.96 , pp. 197-207
    • Adler, P.N.1
  • 4
    • 0035839036 scopus 로고    scopus 로고
    • Gibberellins signal nuclear import of PHOR1, a photoperiod-responsive protein with homology to Drosophila armadillo
    • Amador, V., et al. (2001). Gibberellins signal nuclear import of PHOR1, a photoperiod-responsive protein with homology to Drosophila armadillo. Cell 106, 343-354.
    • (2001) Cell , vol.106 , pp. 343-354
    • Amador, V.1
  • 5
    • 0036571011 scopus 로고    scopus 로고
    • Axin-mediated CKI phosphorylation of β-catenin at Ser 45: A molecular switch for the Wnt pathway
    • Amit, S., et al. (2002). Axin-mediated CKI phosphorylation of β-catenin at Ser 45: A molecular switch for the Wnt pathway. Genes Dev. 16, 1066-1076.
    • (2002) Genes Dev. , vol.16 , pp. 1066-1076
    • Amit, S.1
  • 6
    • 0035873390 scopus 로고    scopus 로고
    • Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling
    • Axelrod, J. D. (2001). Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling. Genes Dev. 15, 1182-1187.
    • (2001) Genes Dev. , vol.15 , pp. 1182-1187
    • Axelrod, J.D.1
  • 7
    • 0036141409 scopus 로고    scopus 로고
    • Strabismus comes into focus
    • Axelrod, J. D. (2002). Strabismus comes into focus. Nat. Cell Biol. 4, E6-E8.
    • (2002) Nat. Cell Biol. , vol.4
    • Axelrod, J.D.1
  • 8
    • 0029670476 scopus 로고    scopus 로고
    • Interaction between Wingless and Notch signaling pathways mediated by dishevelled
    • Axelrod, J. D., et al. (1996). Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science 271, 1826-1832.
    • (1996) Science , vol.271 , pp. 1826-1832
    • Axelrod, J.D.1
  • 9
    • 0032529161 scopus 로고    scopus 로고
    • Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
    • Axelrod, J. D., et al. (1998). Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev. 12, 2610-2622.
    • (1998) Genes Dev. , vol.12 , pp. 2610-2622
    • Axelrod, J.D.1
  • 10
    • 0035839952 scopus 로고    scopus 로고
    • Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins
    • Ayton, P. M., and Cleary, M. L. (2001). Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins. Oncogene 20, 5695-5707.
    • (2001) Oncogene , vol.20 , pp. 5695-5707
    • Ayton, P.M.1    Cleary, M.L.2
  • 11
    • 0034933057 scopus 로고    scopus 로고
    • Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow
    • Bafico, A., et al. (2001). Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat. Cell Biol. 3, 683-686.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 683-686
    • Bafico, A.1
  • 12
    • 0035665719 scopus 로고    scopus 로고
    • The structure of phosphorylated GSK-3β complexed with a peptide. FRATtide, that inhibits β-catenin phosphorylation
    • Bax, B., et al. (2001). The structure of phosphorylated GSK-3β complexed with a peptide, FRATtide, that inhibits β-catenin phosphorylation. Structure (Camb.) 9, 1143-1152.
    • (2001) Structure (Camb.) , vol.9 , pp. 1143-1152
    • Bax, B.1
  • 13
    • 0032562603 scopus 로고    scopus 로고
    • Functional interaction of an axin homolog, conductin, with β-catenin. APC, and GSK3β
    • Behrens, J., et al. (1998). Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β. Science 280, 596-599.
    • (1998) Science , vol.280 , pp. 596-599
    • Behrens, J.1
  • 14
    • 0027386246 scopus 로고
    • Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos
    • Bejsovec, A., and Wieschaus, E. (1993). Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. Development 119, 501-517.
    • (1993) Development , vol.119 , pp. 501-517
    • Bejsovec, A.1    Wieschaus, E.2
  • 15
    • 0029994517 scopus 로고    scopus 로고
    • A new member of the frizzled family from Drosophila functions as a Wingless receptor
    • Bhanot, P., et al. (1996). A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382, 225-230.
    • (1996) Nature , vol.382 , pp. 225-230
    • Bhanot, P.1
  • 16
    • 0032967755 scopus 로고    scopus 로고
    • Dishevelled: At the crossroads of divergent intracellular signaling pathways
    • Boutros, M., and Mlodzik, M. (1999). Dishevelled: At the crossroads of divergent intracellular signaling pathways. Mech. Dev. 83, 27-37.
    • (1999) Mech. Dev. , vol.83 , pp. 27-37
    • Boutros, M.1    Mlodzik, M.2
  • 17
    • 0032504052 scopus 로고    scopus 로고
    • Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
    • Boutros, M., et al. (1998). Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell 94, 109-118.
    • (1998) Cell , vol.94 , pp. 109-118
    • Boutros, M.1
  • 18
    • 0036124896 scopus 로고    scopus 로고
    • TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling
    • Brantjes, H., et al. (2002). TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling. Biol. Chem. 383, 255-261.
    • (2002) Biol. Chem. , vol.383 , pp. 255-261
    • Brantjes, H.1
  • 19
    • 0029793383 scopus 로고    scopus 로고
    • Wingless signaling in the Drosophila eye and embryonic epidermis
    • Cadigan, K. M., and Nusse, R. (1996). Wingless signaling in the Drosophila eye and embryonic epidermis. Development 122, 2801-2812.
    • (1996) Development , vol.122 , pp. 2801-2812
    • Cadigan, K.M.1    Nusse, R.2
  • 20
    • 0035909783 scopus 로고    scopus 로고
    • β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
    • Chen, W., et al. (2001). β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins. Proc. Natl. Acad. Sci. USA 98, 14889-14894.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14889-14894
    • Chen, W.1
  • 21
    • 0036225314 scopus 로고    scopus 로고
    • Dapper, a Dishevelled-associated antagonist of β-catenin and JNK signaling, is required for notochord formation
    • Cheyette, B. N., et al. (2002). Dapper, a Dishevelled-associated antagonist of β-catenin and JNK signaling, is required for notochord formation. Dev. Cell 2, 449-461.
    • (2002) Dev. Cell , vol.2 , pp. 449-461
    • Cheyette, B.N.1
  • 22
    • 0028345607 scopus 로고
    • The wingless signalling pathway and the patterning of the wing margin in Drosophila
    • Couso, J. P., et al. (1994). The wingless signalling pathway and the patterning of the wing margin in Drosophila. Development 120, 621-636.
    • (1994) Development , vol.120 , pp. 621-636
    • Couso, J.P.1
  • 23
    • 0027996069 scopus 로고
    • Notch is required for wingless signaling in the epidermis of Drosophila
    • Couso, J. P., and Martinez Arias, A. (1994). Notch is required for wingless signaling in the epidermis of Drosophila. Cell 79, 259-272.
    • (1994) Cell , vol.79 , pp. 259-272
    • Couso, J.P.1    Martinez Arias, A.2
  • 24
    • 0035936575 scopus 로고    scopus 로고
    • Drosophila par-1 is required for oocyte differentiation and microtubule organization
    • Cox, D. N., et al. (2001). Drosophila par-1 is required for oocyte differentiation and microtubule organization. Curr. Biol. 11, 75-87.
    • (2001) Curr. Biol. , vol.11 , pp. 75-87
    • Cox, D.N.1
  • 25
    • 0036499966 scopus 로고    scopus 로고
    • The planar polarity gene strabismus regulates convergent extension movements in Xenopus
    • Darken, R. S., et al. (2002). The planar polarity gene strabismus regulates convergent extension movements in Xenopus. EMBO J. 21, 976-985.
    • (2002) EMBO J. , vol.21 , pp. 976-985
    • Darken, R.S.1
  • 26
    • 0036111640 scopus 로고    scopus 로고
    • The atypical cadherin Flamingo links Frizzled and Notch signaling in planar polarity establishment in the Drosophila eye
    • Das, G., et al. (2002). The atypical cadherin Flamingo links Frizzled and Notch signaling in planar polarity establishment in the Drosophila eye. Dev. Cell 2, 655-666.
    • (2002) Dev. Cell , vol.2 , pp. 655-666
    • Das, G.1
  • 27
    • 0028131313 scopus 로고
    • The making of a maggot: Patterning the Drosophila embryonic epidermis
    • DiNardo, S., et al. (1994). The making of a maggot: Patterning the Drosophila embryonic epidermis. Curr. Opin. Genet. Dev. 4, 529-534.
    • (1994) Curr. Opin. Genet. Dev. , vol.4 , pp. 529-534
    • DiNardo, S.1
  • 28
    • 0033621616 scopus 로고    scopus 로고
    • Dorsal downregulation of GSK3β by a non-Wnt-like mechanism is an early molecular consequence of cortical rotation in early Xenopus embryos
    • Dominguez, I., and Green, J. B. (2000). Dorsal downregulation of GSK33 by a non-Wnt-like mechanism is an early molecular consequence of cortical rotation in early Xenopus embryos. Development 127, 861-868.
    • (2000) Development , vol.127 , pp. 861-868
    • Dominguez, I.1    Green, J.B.2
  • 29
    • 0026676858 scopus 로고
    • Drosophila wingless generates cell type diversity among engrailed expressing cells
    • Dougan, S., and DiNardo, S. (1992). Drosophila wingless generates cell type diversity among engrailed expressing cells. Nature 360, 347-350.
    • (1992) Nature , vol.360 , pp. 347-350
    • Dougan, S.1    DiNardo, S.2
  • 30
    • 0030604722 scopus 로고    scopus 로고
    • Crystal structures of a complexed and peptide-free membrane protein- binding domain: Molecular basis of peptide recognition by PDZ
    • Doyle, D. A., et al. (1996). Crystal structures of a complexed and peptide-free membrane protein- binding domain: Molecular basis of peptide recognition by PDZ. Cell 85, 1067-1076.
    • (1996) Cell , vol.85 , pp. 1067-1076
    • Doyle, D.A.1
  • 31
    • 0035368514 scopus 로고    scopus 로고
    • Regulated endocytic routing modulates wingless signaling in Drosophila embryos
    • Dubois, L., et al. (2001). Regulated endocytic routing modulates wingless signaling in Drosophila embryos. Cell 105, 613-624.
    • (2001) Cell , vol.105 , pp. 613-624
    • Dubois, L.1
  • 32
    • 0034632672 scopus 로고    scopus 로고
    • The Adenomatous Polyposis Coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain
    • Erdmann, K. S., et al. (2000). The Adenomatous Polyposis Coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain. Oncogene 19, 3894-3901.
    • (2000) Oncogene , vol.19 , pp. 3894-3901
    • Erdmann, K.S.1
  • 33
    • 0033577808 scopus 로고    scopus 로고
    • Domains of axin involved in protein-protein interactions. Wnt pathway inhibition, and intracellular localization
    • Fagotto, F., et al. (1999). Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization. J. Cell Biol. 145, 741-756.
    • (1999) J. Cell Biol. , vol.145 , pp. 741-756
    • Fagotto, F.1
  • 35
    • 0027179703 scopus 로고
    • Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals
    • Fazioli, F., et al. (1993). Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals. EMBO J. 12, 3799-3808.
    • (1993) EMBO J. , vol.12 , pp. 3799-3808
    • Fazioli, F.1
  • 36
    • 0037013313 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β mutagenesis identifies a common binding domain for GBP and Axin
    • Ferkey, D. M., and Kimelman, D. (2002). Glycogen synthase kinase-33 mutagenesis identifies a common binding domain for GBP and Axin. J. Biol. Chem. 277, 16147-16152.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16147-16152
    • Ferkey, D.M.1    Kimelman, D.2
  • 37
    • 0012478261 scopus 로고    scopus 로고
    • The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP
    • Franca-Koh, J., et al. (2002). The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP. J. Biol. Chem. 9, 9.
    • (2002) J. Biol. Chem. , vol.9 , pp. 9
    • Franca-Koh, J.1
  • 38
    • 0037127255 scopus 로고    scopus 로고
    • Identification of the Axin and Frat binding region of glycogen synthase kinase-3
    • Fraser, E., et al. (2002). Identification of the Axin and Frat binding region of glycogen synthase kinase-3. J. Biol. Chem. 277, 2176-2185.
    • (2002) J. Biol. Chem. , vol.277 , pp. 2176-2185
    • Fraser, E.1
  • 39
    • 0033785098 scopus 로고    scopus 로고
    • Effects of rat Axin domains on axis formation in Xenopus embryos
    • Fukui, A., et al. (2000). Effects of rat Axin domains on axis formation in Xenopus embryos. Dev. Growth Differ. 42, 489-498.
    • (2000) Dev. Growth Differ. , vol.42 , pp. 489-498
    • Fukui, A.1
  • 40
    • 0037022275 scopus 로고    scopus 로고
    • Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex
    • Gao, Z. H., et al. (2002). Casein kinase I phosphorylates and destabilizes the 3-catenin degradation complex. Proc. Natl. Acad. Sci. USA 99, 1182-1187.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 1182-1187
    • Gao, Z.H.1
  • 41
    • 0037093441 scopus 로고    scopus 로고
    • Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction
    • Gleason, J. E., et al. (2002). Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction. Genes Dev. 16, 1281-1290.
    • (2002) Genes Dev. , vol.16 , pp. 1281-1290
    • Gleason, J.E.1
  • 42
    • 0012395463 scopus 로고    scopus 로고
    • Frodo interacts with Dishevelled to transduce Wnt signals
    • Gloy, J., et al. (2002). Frodo interacts with Dishevelled to transduce Wnt signals. Nat. Cell Biol. 9, 9.
    • (2002) Nat. Cell Biol. , vol.9 , pp. 9
    • Gloy, J.1
  • 43
    • 0036079896 scopus 로고    scopus 로고
    • The planar cell polarity gene strabismus regulates convergence and extension and neural fold closure in Xenopus
    • Goto, T., and Keller, R. (2002). The planar cell polarity gene strabismus regulates convergence and extension and neural fold closure in Xenopus. Dev. Biol. 247, 165-181.
    • (2002) Dev. Biol. , vol.247 , pp. 165-181
    • Goto, T.1    Keller, R.2
  • 44
    • 0033200334 scopus 로고    scopus 로고
    • The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs
    • Gubb, D., et al. (1999). The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs. Genes Dev. 13, 2315-2327.
    • (1999) Genes Dev. , vol.13 , pp. 2315-2327
    • Gubb, D.1
  • 45
    • 0033018831 scopus 로고    scopus 로고
    • Protein kinase CK2 and its role in cellular proliferation, development and pathology
    • Guerra, B., and Issinger, O. G. (1999). Protein kinase CK2 and its role in cellular proliferation, development and pathology. Electrophoresis 20, 391-408.
    • (1999) Electrophoresis , vol.20 , pp. 391-408
    • Guerra, B.1    Issinger, O.G.2
  • 46
    • 0029024475 scopus 로고
    • par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • Guo, S., and Kemphues, K. J. (1995). par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81, 611-620.
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 47
    • 0035966322 scopus 로고    scopus 로고
    • Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1
    • Habas, R., et al. (2001). Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell 107, 843-854.
    • (2001) Cell , vol.107 , pp. 843-854
    • Habas, R.1
  • 48
    • 0033548495 scopus 로고    scopus 로고
    • Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin
    • Hamada, F., et al. (1999). Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin. Science 283, 1739-1742.
    • (1999) Science , vol.283 , pp. 1739-1742
    • Hamada, F.1
  • 49
    • 0036638049 scopus 로고    scopus 로고
    • Planar cell polarization requires Wilder-borst, a B' regulatory subunit of protein phosphatase 2A
    • Hannus, M., et al. (2002). Planar cell polarization requires Wilder-borst, a B' regulatory subunit of protein phosphatase 2A. Development 129, 3493-3503.
    • (2002) Development , vol.129 , pp. 3493-3503
    • Hannus, M.1
  • 50
    • 0032492954 scopus 로고    scopus 로고
    • Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β
    • Hart, M. J., et al. (1998). Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β. Curr. Biol. 8, 573-581.
    • (1998) Curr. Biol. , vol.8 , pp. 573-581
    • Hart, M.J.1
  • 51
    • 0035479021 scopus 로고    scopus 로고
    • Divide and conquer: Pattern formation in Drosophila embryonic epidermis
    • Hatini, V., and DiNardo, S. (2001). Divide and conquer: Pattern formation in Drosophila embryonic epidermis. Trends Genet. 17, 574-579.
    • (2001) Trends Genet. , vol.17 , pp. 574-579
    • Hatini, V.1    DiNardo, S.2
  • 52
    • 0034604096 scopus 로고    scopus 로고
    • Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation
    • Heisenberg, C. P., et al. (2000). Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature 405, 76-81.
    • (2000) Nature , vol.405 , pp. 76-81
    • Heisenberg, C.P.1
  • 53
    • 0034749352 scopus 로고    scopus 로고
    • Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein
    • Hino, S., et al. (2001). Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein. Mol. Cell. Biol. 21, 330-342.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 330-342
    • Hino, S.1
  • 54
    • 0033524929 scopus 로고    scopus 로고
    • Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain
    • Hsu, W., et al. (1999). Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain. J. Biol. Chem. 274, 3439-3445.
    • (1999) J. Biol. Chem. , vol.274 , pp. 3439-3445
    • Hsu, W.1
  • 55
    • 0037155199 scopus 로고    scopus 로고
    • PDZ domains: Structural modules for protein complex assembly
    • Hung, A. Y., and Sheng, M. (2002). PDZ domains: Structural modules for protein complex assembly. J. Biol. Chem. 277, 5699-5702.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5699-5702
    • Hung, A.Y.1    Sheng, M.2
  • 56
    • 0032473355 scopus 로고    scopus 로고
    • Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β- dependent phosphorylation of β-catenin
    • Ikeda, S., et al. (1998). Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β- dependent phosphorylation of β-catenin. EMBO J. 17, 1371-1384.
    • (1998) EMBO J. , vol.17 , pp. 1371-1384
    • Ikeda, S.1
  • 57
    • 0025815911 scopus 로고
    • Role of the Drosophila patched gene in positional signalling
    • Ingham, P. W., et al. (1991). Role of the Drosophila patched gene in positional signalling. Nature 353, 184-187.
    • (1991) Nature , vol.353 , pp. 184-187
    • Ingham, P.W.1
  • 58
    • 0033539898 scopus 로고    scopus 로고
    • Identification of EPS8 as a Dvl1-associated molecule
    • Inobe, M., et al. (1999). Identification of EPS8 as a Dvl1-associated molecule. Biochem. Biophys. Res. Commun. 266, 216-221.
    • (1999) Biochem. Biophys. Res. Commun. , vol.266 , pp. 216-221
    • Inobe, M.1
  • 59
    • 0033993931 scopus 로고    scopus 로고
    • Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction
    • Itoh, K., et al. (2000). Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction. Mol. Cell. Biol. 20, 2228-2238.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2228-2238
    • Itoh, K.1
  • 60
    • 0032493042 scopus 로고    scopus 로고
    • Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin
    • Itoh, K., et al. (1998). Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin. Curr. Biol. 8, 591-594.
    • (1998) Curr. Biol. , vol.8 , pp. 591-594
    • Itoh, K.1
  • 61
    • 0036047390 scopus 로고    scopus 로고
    • Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements
    • Jessen, J. R., et al. (2002). Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nat. Cell Biol. 8, 8.
    • (2002) Nat. Cell Biol. , vol.8 , pp. 8
    • Jessen, J.R.1
  • 62
    • 0031024689 scopus 로고    scopus 로고
    • Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas
    • Jonkers, J., et al. (1997). Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas. EMBO J. 16, 441-450.
    • (1997) EMBO J. , vol.16 , pp. 441-450
    • Jonkers, J.1
  • 63
    • 0032882253 scopus 로고    scopus 로고
    • In vivo analysis of Frat1 deficiency suggests compensatory activity of
    • Jonkers, J., et al. (1999). In vivo analysis of Frat1 deficiency suggests compensatory activity of. Frat3. Mech. Dev. 88, 183-194.
    • (1999) Frat3. Mech. Dev. , vol.88 , pp. 183-194
    • Jonkers, J.1
  • 64
    • 0034610063 scopus 로고    scopus 로고
    • Domains of axin and disheveled required for interaction and function in wnt signaling
    • Julius, M. A., et al. (2000). Domains of axin and disheveled required for interaction and function in wnt signaling. Biochem. Biophys. Res. Commun. 276, 1162-1169.
    • (2000) Biochem. Biophys. Res. Commun. , vol.276 , pp. 1162-1169
    • Julius, M.A.1
  • 65
    • 34250134008 scopus 로고
    • Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. II. Zygotic loci on the third chromosome
    • Jürgens, G., et al. (1984). Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. II. Zygotic loci on the third chromosome. Roux's Arch. Dev. Biol. 193, 283-295.
    • (1984) Roux's Arch. Dev. Biol. , vol.193 , pp. 283-295
    • Jürgens, G.1
  • 66
    • 0034729910 scopus 로고    scopus 로고
    • Mechanisms of convergence and extension by cell intercalation
    • Keller, R., et al. (2000). Mechanisms of convergence and extension by cell intercalation. Philos. Trans. R. Soc. Lond. B Biol. Sci. 355, 897-922.
    • (2000) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.355 , pp. 897-922
    • Keller, R.1
  • 67
    • 0029374716 scopus 로고
    • Origin of PDZ (DHR, GLGF) domains
    • Kennedy, M. B. (1995). Origin of PDZ (DHR, GLGF) domains. Trends Biochem. Sci. 20, 350.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 350
    • Kennedy, M.B.1
  • 68
    • 0034931874 scopus 로고    scopus 로고
    • Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail
    • Kibar, Z., et al. (2001). Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. Nat. Genet. 28, 251-255.
    • (2001) Nat. Genet. , vol.28 , pp. 251-255
    • Kibar, Z.1
  • 69
    • 0012432518 scopus 로고    scopus 로고
    • Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iε
    • Kishida, M., et al. (2001). Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iε. J. Biol. Chem. 25, 25.
    • (2001) J. Biol. Chem. , vol.25 , pp. 25
    • Kishida, M.1
  • 70
    • 0033011602 scopus 로고    scopus 로고
    • DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate β-catenin stability
    • Kishida, S., et al. (1999). DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate β-catenin stability. Mol. Cell. Biol. 19, 4414-4422.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4414-4422
    • Kishida, S.1
  • 71
    • 0032079884 scopus 로고    scopus 로고
    • Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin
    • Kishida, S., et al. (1998). Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin. J. Biol. Chem. 273, 10823-10826.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10823-10826
    • Kishida, S.1
  • 72
    • 0027954477 scopus 로고
    • The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal
    • Klingensmith, J., et al. (1994). The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. Genes Dev. 8, 118-130.
    • (1994) Genes Dev. , vol.8 , pp. 118-130
    • Klingensmith, J.1
  • 73
    • 0035448902 scopus 로고    scopus 로고
    • The role of maternal axin in patterning the Xenopus embryo
    • Kofron, M., et al. (2001). The role of maternal axin in patterning the Xenopus embryo. Dev. Biol. 237, 183-201.
    • (2001) Dev. Biol. , vol.237 , pp. 183-201
    • Kofron, M.1
  • 74
    • 0037093399 scopus 로고    scopus 로고
    • The Axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans
    • Korswagen, H. C., et al. (2002). The Axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans. Genes Dev. 16, 1291-1302.
    • (2002) Genes Dev. , vol.16 , pp. 1291-1302
    • Korswagen, H.C.1
  • 75
    • 0029417002 scopus 로고
    • Dishevelled is a component of the frizzled signaling pathway in Drosophila
    • Krasnow, R. E., et al. (1995). Dishevelled is a component of the frizzled signaling pathway in Drosophila. Development 121, 4095-4102.
    • (1995) Development , vol.121 , pp. 4095-4102
    • Krasnow, R.E.1
  • 76
    • 0343293801 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus
    • 2+/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus. J. Biol. Chem. 275, 12701-12711.
    • (2000) J. Biol. Chem. , vol.275 , pp. 12701-12711
    • Kuhl, M.1
  • 77
    • 0034214847 scopus 로고    scopus 로고
    • 2+ pathway: A new vertebrate Wnt signaling pathway takes shape
    • 2+ pathway: A new vertebrate Wnt signaling pathway takes shape. Trends Genet. 16, 279-283.
    • (2000) Trends Genet. , vol.16 , pp. 279-283
    • Kuhl, M.1
  • 78
    • 0035669740 scopus 로고    scopus 로고
    • Protein kinase CK2: Signaling and tumorigenesis in the mammary gland
    • Landesman-Bollag, E., et al. (2001). Protein kinase CK2: Signaling and tumorigenesis in the mammary gland. Mol. Cell Biochem. 227, 153-165.
    • (2001) Mol. Cell Biochem. , vol.227 , pp. 153-165
    • Landesman-Bollag, E.1
  • 79
    • 0034676451 scopus 로고    scopus 로고
    • The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5
    • Lanzetti, L., et al. (2000). The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5. Nature 408, 374-377.
    • (2000) Nature , vol.408 , pp. 374-377
    • Lanzetti, L.1
  • 80
    • 0035802116 scopus 로고    scopus 로고
    • Physiological regulation of β-catenin stability by Tcf3 and CK1epsilon
    • Lee, E., et al. (2001). Physiological regulation of β-catenin stability by Tcf3 and CK1epsilon. J. Cell Biol. 154, 983-993.
    • (2001) J. Cell Biol. , vol.154 , pp. 983-993
    • Lee, E.1
  • 81
    • 0033597886 scopus 로고    scopus 로고
    • Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway
    • Lee, J. S., et al. (1999). Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway. J. Biol. Chem. 274, 21464-21470.
    • (1999) J. Biol. Chem. , vol.274 , pp. 21464-21470
    • Lee, J.S.1
  • 82
    • 0037155185 scopus 로고    scopus 로고
    • Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled
    • Li, L., et al. (2002). Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled. J. Biol. Chem. 277, 5977-5981.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5977-5981
    • Li, L.1
  • 83
    • 0033517102 scopus 로고    scopus 로고
    • Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt- mediated regulation of LEF-1
    • Li, L., et al. (1999a). Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt- mediated regulation of LEF-1. EMBO J. 18, 4233-4240.
    • (1999) EMBO J. , vol.18 , pp. 4233-4240
    • Li, L.1
  • 84
    • 0032898364 scopus 로고    scopus 로고
    • Dishevelled proteins lead to two signaling pathways. Regulation of LEF- 1 and c-Jun N-terminal kinase in mammalian cells
    • Li, L., et al. (1999b). Dishevelled proteins lead to two signaling pathways. Regulation of LEF- 1 and c-Jun N-terminal kinase in mammalian cells. J. Biol. Chem. 274, 129-134.
    • (1999) J. Biol. Chem. , vol.274 , pp. 129-134
    • Li, L.1
  • 85
    • 0035423033 scopus 로고    scopus 로고
    • Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus
    • Li, X., et al. (2001). Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus. EMBO J. 20, 4122-4131.
    • (2001) EMBO J. , vol.20 , pp. 4122-4131
    • Li, X.1
  • 86
    • 0034696336 scopus 로고    scopus 로고
    • Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer
    • Li, Y., et al. (2000). Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer. Oncogene 19, 1002-1009.
    • (2000) Oncogene , vol.19 , pp. 1002-1009
    • Li, Y.1
  • 87
    • 0030866899 scopus 로고    scopus 로고
    • Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1
    • Lijam, N., et al. (1997). Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1. Cell 90, 895-905.
    • (1997) Cell , vol.90 , pp. 895-905
    • Lijam, N.1
  • 88
    • 0037155691 scopus 로고    scopus 로고
    • Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism
    • Liu, C., et al. (2002). Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 108, 837-847.
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1
  • 89
    • 0035368394 scopus 로고    scopus 로고
    • G protein signaling from activated rat frizzled-1 to the β-catenin- Lef-Tcf pathway
    • Liu, T., et al. (2001). G protein signaling from activated rat frizzled-1 to the β-catenin- Lef-Tcf pathway. Science 292, 1718-1722.
    • (2001) Science , vol.292 , pp. 1718-1722
    • Liu, T.1
  • 90
    • 18544390789 scopus 로고    scopus 로고
    • Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1
    • Luo, Z. G., et al. (2002). Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1. Neuron 35, 489-505.
    • (2002) Neuron , vol.35 , pp. 489-505
    • Luo, Z.G.1
  • 91
    • 18244427021 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein-5 binds to axin and regulates the canonical wnt signaling pathway
    • Mao, J., et al. (2001). Low-density lipoprotein receptor-related protein-5 binds to axin and regulates the canonical wnt signaling pathway. Mol. Cell 7, 801-809.
    • (2001) Mol. Cell , vol.7 , pp. 801-809
    • Mao, J.1
  • 92
    • 0023895153 scopus 로고
    • Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo
    • Martinez Arias, A., et al. (1988). Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo. Development 103, 157-170.
    • (1988) Development , vol.103 , pp. 157-170
    • Martinez Arias, A.1
  • 93
    • 0033588939 scopus 로고    scopus 로고
    • Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis
    • McCartney, B. M., et al. (1999). Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis. J. Cell Biol. 146, 1303-1318.
    • (1999) J. Cell Biol. , vol.146 , pp. 1303-1318
    • McCartney, B.M.1
  • 94
    • 0034862452 scopus 로고    scopus 로고
    • β-Arrestins: New roles in regulating heptahelical receptors' functions
    • McDonald, P. H., and Lefkowitz, R. J. (2001). β-Arrestins: New roles in regulating heptahelical receptors' functions. Cell. Signal. 13, 683-689.
    • (2001) Cell. Signal. , vol.13 , pp. 683-689
    • McDonald, P.H.1    Lefkowitz, R.J.2
  • 95
    • 0035838385 scopus 로고    scopus 로고
    • Wnt signaling: The Naked truth?
    • McEwen, D. G., and Peifer, M. (2001). Wnt signaling: The Naked truth? Curr. Biol. 11, R524-R526.
    • (2001) Curr. Biol. , vol.11
    • McEwen, D.G.1    Peifer, M.2
  • 96
    • 0035879301 scopus 로고    scopus 로고
    • The casein kinase I family in Wnt signaling
    • McKay, R. M., et al. (2001a). The casein kinase I family in Wnt signaling. Dev. Biol. 235, 388-396.
    • (2001) Dev. Biol. , vol.235 , pp. 388-396
    • McKay, R.M.1
  • 97
    • 0035879317 scopus 로고    scopus 로고
    • The casein kinase I family: Roles in morphogenesis
    • McKay, R. M., et al. (2001b). The casein kinase I family: Roles in morphogenesis. Dev. Biol. 235, 378-387.
    • (2001) Dev. Biol. , vol.235 , pp. 378-387
    • McKay, R.M.1
  • 98
    • 0032759039 scopus 로고    scopus 로고
    • Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo
    • Moline, M. M., et al. (1999). Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo. Development 126, 4375-4384.
    • (1999) Development , vol.126 , pp. 4375-4384
    • Moline, M.M.1
  • 99
    • 0032128173 scopus 로고    scopus 로고
    • From cortical rotation to organizer gene expression: Toward a molecular explanation of axis specification in Xenopus
    • Moon, R. T., and Kimelman, D. (1998). From cortical rotation to organizer gene expression: Toward a molecular explanation of axis specification in Xenopus. Bioessays 20, 536-545.
    • (1998) Bioessays , vol.20 , pp. 536-545
    • Moon, R.T.1    Kimelman, D.2
  • 100
    • 0032695975 scopus 로고    scopus 로고
    • Distinct domains of mouse dishevelled are responsible for the c-Jun N- terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates
    • Moriguchi, T., et al. (1999). Distinct domains of mouse dishevelled are responsible for the c-Jun N- terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates. J. Biol. Chem. 274, 30957-30962.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30957-30962
    • Moriguchi, T.1
  • 101
    • 0033486152 scopus 로고    scopus 로고
    • β-catenin signaling and cancer
    • Morin, P. J. (1999). β-catenin signaling and cancer. Bioessays 21, 1021-1030.
    • (1999) Bioessays , vol.21 , pp. 1021-1030
    • Morin, P.J.1
  • 102
    • 0030949463 scopus 로고    scopus 로고
    • Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
    • Morin, P. J., et al. (1997). Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science 275, 1787-1790.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1
  • 103
    • 0028987249 scopus 로고
    • Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
    • Munemitsu, S., et al. (1995). Regulation of intracellular 3-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc. Natl. Acad. Sci. USA 92, 3046-3050.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3046-3050
    • Munemitsu, S.1
  • 104
    • 0035888642 scopus 로고    scopus 로고
    • Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification
    • Murdoch, J. N., et al. (2001). Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification. Hum. Mol. Genet. 10, 2593-2601.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2593-2601
    • Murdoch, J.N.1
  • 105
    • 0031813650 scopus 로고    scopus 로고
    • Axin, an inhibitor of the Wnt signalling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level
    • Nakamura, T., et al. (1998). Axin, an inhibitor of the Wnt signalling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level. Genes Cells 3, 395-403.
    • (1998) Genes Cells , vol.3 , pp. 395-403
    • Nakamura, T.1
  • 106
    • 0035070912 scopus 로고    scopus 로고
    • Dickkopf1 and the Spemann-Mangold head organizer
    • Niehrs, C., et al. (2001). Dickkopf1 and the Spemann-Mangold head organizer. Int. J. Dev. Biol. 45, 237-240.
    • (2001) Int. J. Dev. Biol. , vol.45 , pp. 237-240
    • Niehrs, C.1
  • 107
    • 0026490172 scopus 로고
    • The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo
    • Noordermeer, J., et al. (1992). The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo. Development 116, 711-719.
    • (1992) Development , vol.116 , pp. 711-719
    • Noordermeer, J.1
  • 108
    • 0028176875 scopus 로고
    • Dishevelled and armadillo act in the wingless signalling pathway in Drosophila
    • Noordermeer, J., et al. (1994). dishevelled and armadillo act in the wingless signalling pathway in Drosophila. Nature 367, 80-83.
    • (1994) Nature , vol.367 , pp. 80-83
    • Noordermeer, J.1
  • 109
    • 0030844356 scopus 로고    scopus 로고
    • Negative regulation of Armadillo, a Wingless effector in Drosophila
    • Pai, L. M., et al. (1997). Negative regulation of Armadillo, a Wingless effector in Drosophila. Development 124, 2255-2266.
    • (1997) Development , vol.124 , pp. 2255-2266
    • Pai, L.M.1
  • 110
    • 0001083966 scopus 로고    scopus 로고
    • The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos
    • Park, M., and Moon, R. T. (2001). The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos. Nat. Cell Biol. 19, 19.
    • (2001) Nat. Cell Biol. , vol.19 , pp. 19
    • Park, M.1    Moon, R.T.2
  • 111
    • 0034053069 scopus 로고    scopus 로고
    • Wnt signaling in oncogenesis and embryogenesis: A look outside the nucleus
    • Peifer, M., and Polakis, P. (2000). Wnt signaling in oncogenesis and embryogenesis: A look outside the nucleus. Science 287, 1606-1609.
    • (2000) Science , vol.287 , pp. 1606-1609
    • Peifer, M.1    Polakis, P.2
  • 112
    • 0028047389 scopus 로고
    • Wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo
    • Peifer, M., et al. (1994). wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo. Development 120, 369-380.
    • (1994) Development , vol.120 , pp. 369-380
    • Peifer, M.1
  • 113
    • 0034535304 scopus 로고    scopus 로고
    • Regulation of G protein-coupled receptor kinases
    • Penn, R. B., et al. (2000). Regulation of G protein-coupled receptor kinases. Trends Cardiovasc. Med. 10, 81-89.
    • (2000) Trends Cardiovasc. Med. , vol.10 , pp. 81-89
    • Penn, R.B.1
  • 114
    • 0035989413 scopus 로고    scopus 로고
    • A mutational analysis of dishevelled in Drosophila defines novel domains in the Dishevelled protein as well as suppressing alleles of axin
    • Penton, A., et al. (2002). A mutational analysis of dishevelled in Drosophila defines novel domains in the Dishevelled protein as well as suppressing alleles of axin. Genetics 161, 747-762.
    • (2002) Genetics , vol.161 , pp. 747-762
    • Penton, A.1
  • 115
    • 0023117211 scopus 로고
    • Multiple functions of segment polarity genes in Drosophila
    • Perrimon, N., and Mahowald, A. P. (1987). Multiple functions of segment polarity genes in Drosophila. Dev. Biol. 119, 587-600.
    • (1987) Dev. Biol. , vol.119 , pp. 587-600
    • Perrimon, N.1    Mahowald, A.P.2
  • 116
    • 0033598401 scopus 로고    scopus 로고
    • Casein kinase I transduces Wnt signals
    • Peters, J. M., et al. (1999). Casein kinase I transduces Wnt signals. Nature 401, 345-350.
    • (1999) Nature , vol.401 , pp. 345-350
    • Peters, J.M.1
  • 117
    • 0037107552 scopus 로고    scopus 로고
    • Protein kinase CK2: A challenge to canons
    • Pinna, L. A. (2002). Protein kinase CK2: A challenge to canons. J. Cell Sci. 115, 3873-3878.
    • (2002) J. Cell Sci. , vol.115 , pp. 3873-3878
    • Pinna, L.A.1
  • 118
    • 0034727078 scopus 로고    scopus 로고
    • An LDL-receptor-related protein mediates Wnt signalling in mice
    • Pinson, K. I., et al. (2000). An LDL-receptor-related protein mediates Wnt signalling in mice. Nature 407, 535-538.
    • (2000) Nature , vol.407 , pp. 535-538
    • Pinson, K.I.1
  • 119
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis, P. (2000). Wnt signaling and cancer. Genes Dev. 14, 1837-1851.
    • (2000) Genes Dev. , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 120
    • 0033083490 scopus 로고    scopus 로고
    • Using GFP in FRET-based applications
    • Pollok, B. A., and Heim, R. (1999). Using GFP in FRET-based applications. Trends Cell Biol. 9, 57-60.
    • (1999) Trends Cell Biol. , vol.9 , pp. 57-60
    • Pollok, B.A.1    Heim, R.2
  • 121
    • 0030200001 scopus 로고    scopus 로고
    • Pleckstrin's repeat performance: A novel domain in G-protein signaling?
    • Ponting, C. P., and Bork, P. (1996). Pleckstrin's repeat performance: A novel domain in G-protein signaling? Trends Biochem. Sci. 21, 245-246.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 245-246
    • Ponting, C.P.1    Bork, P.2
  • 122
    • 0034680788 scopus 로고    scopus 로고
    • A positive role for the PP2A catalytic subunit in Wnt signal transduction
    • Ratcliffe, M. J., et al. (2000). A positive role for the PP2A catalytic subunit in Wnt signal transduction. J. Biol. Chem. 275, 35680-35683.
    • (2000) J. Biol. Chem. , vol.275 , pp. 35680-35683
    • Ratcliffe, M.J.1
  • 123
    • 0036094925 scopus 로고    scopus 로고
    • Par-1 regulates stability of the posterior determinant Oskar by phosphorylation
    • Riechmann, V., et al. (2002). Par-1 regulates stability of the posterior determinant Oskar by phosphorylation. Nat. Cell Biol. 4, 337-342.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 337-342
    • Riechmann, V.1
  • 124
    • 0033783132 scopus 로고    scopus 로고
    • GTPase-activating proteins for heterotrimeric G proteins: Regulators of G protein signaling (RGS) and RGS-like proteins
    • Ross, E. M., and Wilkie, T. M. (2000). GTPase-activating proteins for heterotrimeric G proteins: Regulators of G protein signaling (RGS) and RGS-like proteins. Annu. Rev. Biochem. 69, 795-827.
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 795-827
    • Ross, E.M.1    Wilkie, T.M.2
  • 125
    • 0242690871 scopus 로고    scopus 로고
    • Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis
    • Rothbacher, U., et al. (2000). Dishevelled phosphorylation, subcel-lular localization and multimerization regulate its role in early embryogenesis. EMBO J. 19, 1010-1022.
    • (2000) EMBO J. , vol.19 , pp. 1010-1022
    • Rothbacher, U.1
  • 126
    • 0035869002 scopus 로고    scopus 로고
    • Naked cuticle targets dishevelled to antagonize Wnt signal transduction
    • Rousset, R., et al. (2001). Naked cuticle targets dishevelled to antagonize Wnt signal transduction. Genes Dev. 15, 658-671.
    • (2001) Genes Dev. , vol.15 , pp. 658-671
    • Rousset, R.1
  • 127
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly
    • Rubinfeld, B., et al. (1996). Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly. Science 272, 1023-1026.
    • (1996) Science , vol.272 , pp. 1023-1026
    • Rubinfeld, B.1
  • 128
    • 0029904837 scopus 로고    scopus 로고
    • Wingless refines its own expression domain on the Drosophila wing margin
    • Rulifson, E. J., et al. (1996). Wingless refines its own expression domain on the Drosophila wing margin. Nature 384, 72-74.
    • (1996) Nature , vol.384 , pp. 72-74
    • Rulifson, E.J.1
  • 129
    • 0034815118 scopus 로고    scopus 로고
    • Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway
    • Saitoh, T., et al. (2001). Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway. Biochem. Biophys. Res. Commun. 281, 815-820.
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , pp. 815-820
    • Saitoh, T.1
  • 130
    • 0033607057 scopus 로고    scopus 로고
    • Casein kinase iε in the wnt pathway: Regulation of β-catenin function
    • Sakanaka, C., et al. (1999). Casein kinase iε in the wnt pathway: Regulation of β-catenin function. Proc. Natl. Acad. Sci. USA 96, 12548-12552.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 12548-12552
    • Sakanaka, C.1
  • 131
    • 0032539945 scopus 로고    scopus 로고
    • Bridging of β-catenin and glycogen synthase kinase-3β by axin and inhibition of β-catenin-mediated transcription
    • Sakanaka, C., et al. (1998). Bridging of β-catenin and glycogen synthase kinase-3β by axin and inhibition of β-catenin-mediated transcription. Proc. Natl. Acad. Sci. USA 95, 3020-3023.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3020-3023
    • Sakanaka, C.1
  • 132
    • 0033553491 scopus 로고    scopus 로고
    • Functional domains of axin. Importance of the C terminus as an oligomerization domain
    • Sakanaka, C., and Williams, L. T. (1999). Functional domains of axin. Importance of the C terminus as an oligomerization domain. J. Biol. Chem. 274, 14090-14093.
    • (1999) J. Biol. Chem. , vol.274 , pp. 14090-14093
    • Sakanaka, C.1    Williams, L.T.2
  • 133
    • 0035511932 scopus 로고    scopus 로고
    • Induction, assembly, maturation and maintenance of a postsynaptic apparatus
    • Sanes, J. R., and Lichtman, J. W. (2001). Induction, assembly, maturation and maintenance of a postsynaptic apparatus. Nat. Rev. Neurosci. 2, 791-805.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 791-805
    • Sanes, J.R.1    Lichtman, J.W.2
  • 134
    • 0037118064 scopus 로고    scopus 로고
    • The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos
    • Saneyoshi, T., et al. (2002). The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos. Nature 417, 295-299.
    • (2002) Nature , vol.417 , pp. 295-299
    • Saneyoshi, T.1
  • 135
    • 0034088858 scopus 로고    scopus 로고
    • AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
    • Satoh, S., et al. (2000). AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat. Genet. 24, 245-250.
    • (2000) Nat. Genet. , vol.24 , pp. 245-250
    • Satoh, S.1
  • 136
    • 0033575885 scopus 로고    scopus 로고
    • EPS8 and E3B1 transduce signals from Ras to Rac
    • Scita, G., et al. (1999). EPS8 and E3B1 transduce signals from Ras to Rac. Nature 401, 290-293.
    • (1999) Nature , vol.401 , pp. 290-293
    • Scita, G.1
  • 137
    • 0033605639 scopus 로고    scopus 로고
    • Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A
    • Seeling, J. M., et al. (1999). Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A. Science 283, 2089-2091.
    • (1999) Science , vol.283 , pp. 2089-2091
    • Seeling, J.M.1
  • 138
    • 0031172433 scopus 로고    scopus 로고
    • Human dishevelled genes constitute a DHR-containing multigene family
    • Semenov, M. V., and Snyder, M. (1997). Human dishevelled genes constitute a DHR-containing multigene family. Genomics 42, 302-310.
    • (1997) Genomics , vol.42 , pp. 302-310
    • Semenov, M.V.1    Snyder, M.2
  • 139
    • 0027948042 scopus 로고
    • Components of wingless signalling in Drosophila
    • Siegfried, E., et al. (1994). Components of wingless signalling in Drosophila. Nature 367, 76-80.
    • (1994) Nature , vol.367 , pp. 76-80
    • Siegfried, E.1
  • 140
    • 0033577732 scopus 로고    scopus 로고
    • Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF- dependent transcription
    • Smalley, M. J., et al. (1999). Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF- dependent transcription. EMBO J. 18, 2823-2835.
    • (1999) EMBO J. , vol.18 , pp. 2823-2835
    • Smalley, M.J.1
  • 141
    • 0030293782 scopus 로고    scopus 로고
    • Analysis of Dishevelled signalling pathways during Xenopus development
    • Sokol, S. Y. (1996). Analysis of Dishevelled signalling pathways during Xenopus development. Curr. Biol. 6, 1456-1467.
    • (1996) Curr. Biol. , vol.6 , pp. 1456-1467
    • Sokol, S.Y.1
  • 142
    • 0029393740 scopus 로고
    • Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled
    • Sokol, S. Y., et al. (1995). Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled. Development 121, 3487.
    • (1995) Development , vol.121 , pp. 3487
    • Sokol, S.Y.1
  • 143
    • 0034604726 scopus 로고    scopus 로고
    • Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells
    • Song, D. H., et al. (2000). Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells. J. Biol. Chem. 275, 23790-23797.
    • (2000) J. Biol. Chem. , vol.275 , pp. 23790-23797
    • Song, D.H.1
  • 144
    • 0034657187 scopus 로고    scopus 로고
    • Structural basis of the Axin-adenomatous polyposis coli interaction
    • Spink, K. E., et al. (2000). Structural basis of the Axin-adenomatous polyposis coli interaction. EMBO J. 19, 2270-2279.
    • (2000) EMBO J. , vol.19 , pp. 2270-2279
    • Spink, K.E.1
  • 145
    • 0034723073 scopus 로고    scopus 로고
    • Protein phosphatase 2Cα dephosphorylates axin and activates LEF-1- dependent transcription
    • Strovel, E. T., et al. (2000). Protein phosphatase 2Cα dephosphorylates axin and activates LEF-1- dependent transcription. J. Biol. Chem. 275, 2399-2403.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2399-2403
    • Strovel, E.T.1
  • 146
    • 0037076213 scopus 로고    scopus 로고
    • Asymmetric localization of frizzled and the determination of notch-dependent cell fate in the Drosophila eye
    • Strutt, D., et al. (2002). Asymmetric localization of frizzled and the determination of notch-dependent cell fate in the Drosophila eye. Curr. Biol. 12, 813-824.
    • (2002) Curr. Biol. , vol.12 , pp. 813-824
    • Strutt, D.1
  • 147
    • 0035108427 scopus 로고    scopus 로고
    • Asymmetric localization of frizzled and the establishment of cell polarity in the Drosophila wing
    • Strutt, D. I. (2001). Asymmetric localization of frizzled and the establishment of cell polarity in the Drosophila wing. Mol. Cell 7, 367-375.
    • (2001) Mol. Cell , vol.7 , pp. 367-375
    • Strutt, D.I.1
  • 148
    • 0030917227 scopus 로고    scopus 로고
    • The role of RhoA in tissue polarity and Frizzled signalling
    • Strutt, D. I., et al. (1997). The role of RhoA in tissue polarity and Frizzled signalling. Nature 387, 292-295.
    • (1997) Nature , vol.387 , pp. 292-295
    • Strutt, D.I.1
  • 149
    • 0034943604 scopus 로고    scopus 로고
    • PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling
    • Sun, T. Q., et al. (2001). PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling. Nat. Cell Biol. 3, 628-636.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 628-636
    • Sun, T.Q.1
  • 150
    • 0034727104 scopus 로고    scopus 로고
    • LDL-receptor-related proteins in Wnt signal transduction
    • Tamai, K., et al. (2000). LDL-receptor-related proteins in Wnt signal transduction. Nature 407, 530-535.
    • (2000) Nature , vol.407 , pp. 530-535
    • Tamai, K.1
  • 151
    • 0034772624 scopus 로고    scopus 로고
    • Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development
    • Tan, C., et al. (2001). Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development. Development 128, 3665-3674.
    • (2001) Development , vol.128 , pp. 3665-3674
    • Tan, C.1
  • 152
    • 0031688426 scopus 로고    scopus 로고
    • Van Gogh: A new Drosophila tissue polarity gene
    • Taylor, J., et al. (1998). Van Gogh: A new Drosophila tissue polarity gene. Genetics 150, 199-210.
    • (1998) Genetics , vol.150 , pp. 199-210
    • Taylor, J.1
  • 153
    • 0028178391 scopus 로고
    • Dishevelled is required during wingless signaling to establish both cell polarity and cell identity
    • Theisen, H., et al. (1994). Dishevelled is required during wingless signaling to establish both cell polarity and cell identity. Development 120, 347-360.
    • (1994) Development , vol.120 , pp. 347-360
    • Theisen, H.1
  • 154
    • 0034717582 scopus 로고    scopus 로고
    • Colocalization and redistribution of dishevelled and actin during Wnt- induced mesenchymal morphogenesis
    • Torres, M. A., and Nelson, W. J. (2000). Colocalization and redistribution of dishevelled and actin during Wnt- induced mesenchymal morphogenesis. J. Cell Biol. 149, 1433-1442.
    • (2000) J. Cell Biol. , vol.149 , pp. 1433-1442
    • Torres, M.A.1    Nelson, W.J.2
  • 155
    • 0037013168 scopus 로고    scopus 로고
    • Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling
    • Tree, D. R., et al. (2002). Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell 109, 371-381.
    • (2002) Cell , vol.109 , pp. 371-381
    • Tree, D.R.1
  • 156
    • 0033520466 scopus 로고    scopus 로고
    • Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled
    • Usui, T., et al. (1999). Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. Cell 98, 585-595.
    • (1999) Cell , vol.98 , pp. 585-595
    • Usui, T.1
  • 157
    • 0036570588 scopus 로고    scopus 로고
    • Role of Rho family GTPases in epithelial morphogenesis
    • Van Aelst, L., and Symons, M. (2002). Role of Rho family GTPases in epithelial morphogenesis. Genes Dev. 16, 1032-1054.
    • (2002) Genes Dev. , vol.16 , pp. 1032-1054
    • Van Aelst, L.1    Symons, M.2
  • 158
    • 0034933482 scopus 로고    scopus 로고
    • Casein kinase I: From obscurity to center stage
    • Vielhaber, E., and Virshup, D. M. (2001). Casein kinase I: From obscurity to center stage. IUBMB Life 51, 73-78.
    • (2001) IUBMB Life , vol.51 , pp. 73-78
    • Vielhaber, E.1    Virshup, D.M.2
  • 159
    • 0024972122 scopus 로고
    • A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains
    • Vinson, C. R., et al. (1989). A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains. Nature 338, 263-264.
    • (1989) Nature , vol.338 , pp. 263-264
    • Vinson, C.R.1
  • 160
    • 84876167876 scopus 로고
    • Penguin Putnam, Inc., New York, NY
    • Voltaire, F.-M. A. Translated by John Butt. (1990). "Candide." Penguin Putnam, Inc., New York, NY.
    • (1990) "Candide"
    • Voltaire, F.-M.A.1    Butt, J.2
  • 161
    • 0034915909 scopus 로고    scopus 로고
    • Xenopus Dishevelled signaling regulates both neural and mesodermal convergent extension: Parallel forces elongating the body axis
    • Wallingford, J. B., and Harland, R. M. (2001). Xenopus Dishevelled signaling regulates both neural and mesodermal convergent extension: Parallel forces elongating the body axis. Development 128, 2581-2592.
    • (2001) Development , vol.128 , pp. 2581-2592
    • Wallingford, J.B.1    Harland, R.M.2
  • 162
    • 0034604076 scopus 로고    scopus 로고
    • Dishevelled controls cell polarity during Xenopus gastrulation
    • Wallingford, J. B., et al. (2000). Dishevelled controls cell polarity during Xenopus gastrulation. Nature 405, 81-85.
    • (2000) Nature , vol.405 , pp. 81-85
    • Wallingford, J.B.1
  • 163
    • 0032031388 scopus 로고    scopus 로고
    • FH proteins as cytoskeletal organizers
    • Wasserman, S. (1998). FH proteins as cytoskeletal organizers. Trends Cell Biol. 8, 111-115.
    • (1998) Trends Cell Biol. , vol.8 , pp. 111-115
    • Wasserman, S.1
  • 164
    • 0034727099 scopus 로고    scopus 로고
    • Arrow encodes an LDL-receptor-related protein essential for Wingless signalling
    • Wehrli, M., et al. (2000). Arrow encodes an LDL-receptor-related protein essential for Wingless signalling. Nature 407, 527-530.
    • (2000) Nature , vol.407 , pp. 527-530
    • Wehrli, M.1
  • 165
    • 0035370984 scopus 로고    scopus 로고
    • Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling
    • Wharton, K. A., Jr., et al. (2001). Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling. Dev. Biol. 234, 93-106.
    • (2001) Dev. Biol. , vol.234 , pp. 93-106
    • Wharton K.A., Jr.1
  • 166
    • 0030973456 scopus 로고    scopus 로고
    • Casein kinase 2 associates with and phosphorylates dishevelled
    • Willert, K., et al. (1997). Casein kinase 2 associates with and phosphorylates dishevelled. EMBO J. 16, 3089-3096.
    • (1997) EMBO J. , vol.16 , pp. 3089-3096
    • Willert, K.1
  • 167
    • 0032841989 scopus 로고    scopus 로고
    • A Drosophila Axin homolog, Daxin, inhibits Wnt signaling
    • Willert, K., et al. (1999a). A Drosophila Axin homolog, Daxin, inhibits Wnt signaling. Development 126, 4165-4173.
    • (1999) Development , vol.126 , pp. 4165-4173
    • Willert, K.1
  • 168
    • 0033565533 scopus 로고    scopus 로고
    • Wnt-induced dephosphorylation of axin releases β-catenin from the axin complex
    • Willert, K., et al. (1999b). Wnt-induced dephosphorylation of axin releases β-catenin from the axin complex. Genes Dev. 13, 1768-1773.
    • (1999) Genes Dev. , vol.13 , pp. 1768-1773
    • Willert, K.1
  • 169
    • 0035950183 scopus 로고    scopus 로고
    • Frizzled-7 signalling controls tissue separation during Xenopus gastrulation
    • Winklbauer, R., et al. (2001). Frizzled-7 signalling controls tissue separation during Xenopus gastrulation. Nature 413, 856-860.
    • (2001) Nature , vol.413 , pp. 856-860
    • Winklbauer, R.1
  • 170
    • 0035815280 scopus 로고    scopus 로고
    • Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton
    • Winter, C. G., et al. (2001). Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton. Cell 105, 81-91.
    • (2001) Cell , vol.105 , pp. 81-91
    • Winter, C.G.1
  • 171
    • 0031918915 scopus 로고    scopus 로고
    • Strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila
    • Wolff, T., and Rubin, G. M. (1998). Strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila. Development 125, 1149-1159.
    • (1998) Development , vol.125 , pp. 1149-1159
    • Wolff, T.1    Rubin, G.M.2
  • 172
    • 0033669627 scopus 로고    scopus 로고
    • Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway
    • Wong, H. C., et al. (2000). Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway. Nat. Struct. Biol. 7, 1178-1184.
    • (2000) Nat. Struct. Biol. , vol.7 , pp. 1178-1184
    • Wong, H.C.1
  • 173
    • 0012465590 scopus 로고    scopus 로고
    • Inhibition of the Wnt signaling pathway by the PR61 subunit of protein phosphatase 2A
    • Yamamoto, H., et al. (2001). Inhibition of the Wnt signaling pathway by the PR61 subunit of protein phosphatase 2A. J. Biol. Chem. 10, 10.
    • (2001) J. Biol. Chem. , vol.10 , pp. 10
    • Yamamoto, H.1
  • 174
    • 0033574527 scopus 로고    scopus 로고
    • Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability
    • Yamamoto, H., et al. (1999). Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability. J. Biol. Chem. 274, 10681-10684.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10681-10684
    • Yamamoto, H.1
  • 175
    • 0035957382 scopus 로고    scopus 로고
    • Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
    • Yan, D., et al. (2001a). Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd. Proc. Natl. Acad. Sci. USA 98, 3802-3807.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 3802-3807
    • Yan, D.1
  • 176
    • 18244389736 scopus 로고    scopus 로고
    • Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/β-catenin signaling is activated in human colon tumors
    • Yan, D., et al. (2001b). Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/β-catenin signaling is activated in human colon tumors. Proc. Natl. Acad. Sci. USA 98, 14973-14978.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14973-14978
    • Yan, D.1
  • 177
    • 0037007231 scopus 로고    scopus 로고
    • Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila
    • Yanagawa, S., et al. (2002). Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila. EMBO J. 21, 1733-1742.
    • (2002) EMBO J. , vol.21 , pp. 1733-1742
    • Yanagawa, S.1
  • 178
    • 0028989112 scopus 로고
    • The dishevelled protein is modified by wingless signaling in Drosophila
    • Yanagawa, S., et al. (1995). The dishevelled protein is modified by wingless signaling in Drosophila. Genes Dev. 9, 1087-1097.
    • (1995) Genes Dev. , vol.9 , pp. 1087-1097
    • Yanagawa, S.1
  • 179
    • 0032511194 scopus 로고    scopus 로고
    • GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis
    • Yost, C., et al. (1998). GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis. Cell 93, 1031-1041.
    • (1998) Cell , vol.93 , pp. 1031-1041
    • Yost, C.1
  • 180
    • 0031457978 scopus 로고    scopus 로고
    • The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation
    • Zeng, L., et al. (1997). The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell 90, 181-192.
    • (1997) Cell , vol.90 , pp. 181-192
    • Zeng, L.1
  • 181
    • 0034677490 scopus 로고    scopus 로고
    • Naked cuticle encodes an inducible antagonist of Wnt signalling
    • Zeng, W., et al. (2000). naked cuticle encodes an inducible antagonist of Wnt signalling. Nature 403, 789-795.
    • (2000) Nature , vol.403 , pp. 789-795
    • Zeng, W.1
  • 182
    • 0012388369 scopus 로고    scopus 로고
    • Differential molecular assemblies underlie dual function of axin in modulating the Wnt and JNK pathways
    • Zhang, Y., et al.. (2001). Differential molecular assemblies underlie dual function of axin in modulating the Wnt and JNK pathways. J. Biol. Chem. 14, 14.
    • (2001) J. Biol. Chem. , vol.14 , pp. 14
    • Zhang, Y.1
  • 183
    • 0029145518 scopus 로고
    • Frizzled regulates mirror-symmetric pattern formation in the Drosophila eye
    • Zheng, L., et al.. (1995). Frizzled regulates mirror-symmetric pattern formation in the Drosophila eye. Development 121, 3045-3055.
    • (1995) Development , vol.121 , pp. 3045-3055
    • Zheng, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.