β-Catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator

Molecular and Cellular Biology

Volumn 20, Issue 18, 2000, Pages 6882-6890

  Billin, A N ^a   Thirlwell, H ^a   Ayer, D E ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; HISTONE DEACETYLASE;

ARTICLE; GENE EXPRESSION REGULATION; GENE TARGETING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REPORTER GENE; TRANSCRIPTION REGULATION;

BETA CATENIN; CELL LINE; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; HELA CELLS; HISTONE DEACETYLASES; HUMANS; LYMPHOID ENHANCER-BINDING FACTOR 1; REPRESSOR PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0033817339     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.18.6882-6890.2000     Document Type: Article

References (58)

1. Histone deacetylases: Transcriptional repression with SINers and NuRDs
2. A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation
3. Functional interaction of beta-catenin with the transcription factor LEF-1
4. TCF: Transcriptional activator or repressor?
5. Regulation of activity of the transcription factor GATA-1 by acetylation
6. XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development
7. A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus
8. Wnt signaling: A common theme in animal development
9. HDA1 and HDA3 are components of a yeast histone deacetylase (HDA) complex
10. Armadillo and dTCF: A marriage made in the nucleus
11. Drosophila Tcf and Groucho interact to repress Wingless signalling activity
12. A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity
13. A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development
14. TCF/LEF factor earn their wings
15. Net, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylation
16. Covalent modifications of histones: Expression from chromatin templates
17. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
18. Carcinogenesis: A balance between beta-catenin and APC
19. Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A
20. Histone deacetylase activity is required for full transcriptional repression by mSin3A
21. Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs
22. Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro
23. Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin
24. Nuclear localization of beta-catenin by interaction with transcription factor LEF-1
25. Acetylation of general transcription factors by histone acetyltransferases
26. Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters
27. A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators
28. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
29. Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
30. Roles of histone acetyltransferases and deacetylases in gene regulation
31. SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors
32. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression
33. Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II
34. Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors
35. Xenopus NF-Y pre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the xenopus hsp70 promoter in vivo
36. p300 stimulates transcription instigated by ligand-bound thyroid hormone receptor at a step subsequent to chromatin disruption
37. A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor
38. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
39. Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome
40. The Groucho/transducin-like enhancer of split transcriptional repressors interact with the genetically defined amino-terminal silencing domain of histone H3
41. Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins
42. What's up and down with histone deacetylation and transcription?
43. Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin
44. LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic
45. Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos
46. The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
47. Stabilization of beta-catenin by genetic defects in melanoma cell lines
48. DNA damage activates p53 through a phosphorylation-acetylation cascade
49. The carboxy-terminal region of adenovirus E1A activates transcription through targeting of a C-terminal binding protein-histone deacetylase complex
50. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
51. Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm
52. Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex
53. Co-activators and co-repressors in the integration of transcriptional responses
54. Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF
55. A multiple subunit Mi-2 histone deacetylase from Xenopus laevis cofractionates with an associated Snf2 superfamily ATPase
56. NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities
57. Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex
58. The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities