Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

EMBO Journal

Volumn 22, Issue 23, 2003, Pages 6267-6276

  Winkler, David G ^a   Sutherland, May Kung ^a   Geoghegan, James C ^a   Yu, Changpu ^a   Hayes, Trenton ^a   Skonier, John E ^a   Shpektor, Diana ^a   Jonas, Mechtild ^a   Kovacevich, Brian R ^a   Staehling Hampton, Karen ^a   Appleby, Mark ^a   Brunkow, Mary E ^a   Latham, John A ^a  

^a Celltech R and D Inc   (United States)

Author keywords

BMP; Mineralization; Osteocyte; Osteoporosis; SOST

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; GENE PRODUCT; PROCOLLAGEN C PROTEINASE; PROTEIN; SCLEROSTIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE DISEASE; BONE MASS; BONE MINERALIZATION; CONTROLLED STUDY; EMBRYO; GENE; GENE EXPRESSION; HOMEOSTASIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; OSTEOBLAST; OSTEOCYTE; OSTEOSCLEROSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; SOST GENE;

ALKALINE PHOSPHATASE; ANIMALS; BASE SEQUENCE; BONE DENSITY; BONE DEVELOPMENT; BONE DISEASES, METABOLIC; BONE MORPHOGENETIC PROTEINS; CELL LINE; CLONING, MOLECULAR; DNA PRIMERS; GENETIC MARKERS; HUMANS; KINETICS; MESODERM; MICE; MICE, INBRED C3H; MICE, TRANSGENIC; OSTEOCYTES; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA; MUS MUSCULUS;

EID: 10744221383     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg599     Document Type: Article

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