Single minimally invasive surgical technique with an enamel matrix derivative to treat multiple adjacent intra-bony defects: Clinical outcomes and patient morbidity

Journal of Clinical Periodontology

Volumn 35, Issue 7, 2008, Pages 605-613

  Cortellini, Pierpaolo ^a,b,d   Nieri, Michele ^c   Pini Prato, Giovanpaolo ^c   Tonetti, Maurizio S ^b  

^a Accademia Toscana di Ricerca Odontostomatologica   (Italy)

^b European Research Group on Periodontology ERGOPerio   (Switzerland)

^c UNIVERSITY OF FLORENCE   (Italy)

^d NONE   (Italy)

Author keywords

Clinical trial; Microsurgery; Osseous defects; Periodontal diseases; Periodontal regeneration

Indexed keywords

ENAMEL MATRIX PROTEINS; ENAMEL PROTEIN;

ADULT; ARTICLE; BONE PROSTHESIS; CLINICAL TRIAL; COHORT ANALYSIS; FEMALE; FOLLOW UP; HOSPITALIZATION; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; MINIMALLY INVASIVE SURGERY; NONPARAMETRIC TEST; OSTEOLYSIS; PATIENT SATISFACTION; PERIODONTAL DISEASE; PERIODONTICS; POSTOPERATIVE PAIN; SUTURING METHOD; TREATMENT OUTCOME;

ADULT; ALVEOLAR BONE LOSS; BONE SUBSTITUTES; COHORT STUDIES; DENTAL ENAMEL PROTEINS; FEMALE; FOLLOW-UP STUDIES; GUIDED TISSUE REGENERATION, PERIODONTAL; HUMANS; MALE; MIDDLE AGED; PAIN, POSTOPERATIVE; PATIENT SATISFACTION; PERIODONTAL ATTACHMENT LOSS; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC; SURGICAL PROCEDURES, MINIMALLY INVASIVE; SUTURE TECHNIQUES; TREATMENT OUTCOME;

EID: 44849136948     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2008.01242.x     Document Type: Article

References (30)

1. Cortellini, P., Pini-Prato, G. P. Tonetti, M. S. (1993a) Periodontal regeneration of human infrabony defects. I. clinical measures. Journal of Periodontology 64, 254 260.
2. Cortellini, P., Pini-Prato, G. P. Tonetti, M. S. (1993b) Periodontal regeneration of human infrabony defects. II. Re-entry procedures and bone measures. Journal of Periodontology 64, 261 268.
3. Cortellini, P., Pini Prato, G. Tonetti, M. S. (1995) The modified papilla preservation technique. A new surgical approach for interproximal regenerative procedures. Journal of Periodontology 66, 261 266.
4. Cortellini, P., Pini Prato, G. Tonetti, M. S. (1999) The simplified papilla preservation flap. A novel surgical approach for the management of soft tissues in regenerative procedures. International Journal of Periodontics & Restorative Dentistry 19, 589 599.
5. Cortellini, P. Tonetti, M. S. (2000) Focus on intrabony defects: guided tissue regeneration. Periodontology 2000 22, 104 132.
6. Cortellini, P. Tonetti, M. S. (2001) Microsurgical approach to periodontal regeneration. Initial evaluation in a case cohort. Journal of Periodontology 72, 559 569.
7. Cortellini, P. Tonetti, M. S. (2005) Clinical performance of a regenerative strategy for intrabony defects. Scientific evidence and clinical experience. Journal of Periodontology 76, 341 350.
8. Cortellini, P. Tonetti, M. S. (2007a) A minimally invasive surgical technique (MIST) with enamel matrix derivate in the regenerative treatment of intrabony defects: a novel approach to limit morbidity. Journal of Clinical Periodontology 34, 87 93.
9. Cortellini, P. Tonetti, M. S. (2007b) Minimally invasive surgical technique (MIST) and enamel matrix derivative (EMD) in intrabony defects. (I) Clinical outcomes and morbidity. Journal of Clinical Periodontology 34, 1082 1088.
10. Cortellini, P., Tonetti, M. S., Lang, N. P., Suvan, J. E., Zucchelli, G., Vangsted, T., Silvestri, M., Rossi, R., McClain, P., Fonzar, A., Dubravec, D. Adriaens, P. (2001) The simplified papilla preservation flap in the regenerative treatment of deep intrabony defects: clinical outcomes and postoperative morbidity. Journal of Periodontology 72, 1702 1712.
11. Ellegaard, B. Loe, H. (1971) New attachment of periodontal tissues after treatment of intrabony lesions. Journal of Periodontology 42, 648 652.
12. Esposito, M., Grusovin, M. G., Coulthard, P. Worthington, H. V. Enamel matrix derivative (Emdogain) for periodontal tissue regeneration in intrabony defects. Cochrane Database Systematic Reviews, 19 October 2005 (4): CD003875 (review).
13. Gelman, A. Hill, J. (2007) Data Analysis Using Regression and Multilevel/Hierarchical Models, pp. 473 477. Cambridge : Cambridge University press.
14. Haney, J. M., Nilveus, R. E., McMillan, P. J. Wikesjo, U. M. (1993) Periodontal repair in dogs: expanded polytetrafluorethylene barrier membrane support wound stabilisation and enhance bone regeneration. Journal of Periodontology 64, 883 890.
15. Harrel, S. K. Nunn, M. E. (2001) Longitudinal comparison of the periodontal status of patients with moderate to severe periodontal disease receiving no treatment, non-surgical treatment, and surgical treatment utilizing individual sites for analysis. Journal of Periodontology 72, 1509 1519.
16. Harrel, S. K. Rees, T. D. (1995) Granulation tissue removal in routine and minimally invasive surgical procedures. Compendium of Continuing Education Dentistry 16, 960 967.
17. Harrel, S. K., Wilson, T. G, Jr. Nunn, M. E. (2005) Prospective assessment of the use of enamel matrix proteins with minimally invasive surgery. Journal of Periodontology 76, 380 384.
18. Hiatt, W. H., Stallard, R. E., Butler, E. D. Badget, B. (1968) Repair following mucoperiosteal flap surgery with full gingival retention. Journal of Periodontology 39, 11 16.
19. Murphy, K. G. Gunsolley, J. C. (2003) Guided tissue regeneration for the treatment of periodontal intrabony and furcation defects. A systematic review. Annals of Periodontology 8, 266 302.
20. Needleman, I., Tucker, R., Giedrys-Leeper, E. Worthington, H. (2002) A systematic review of guided tissue regeneration for periodontal infrabony defects. Journal of Periodontal Research 37, 380 388.
21. Needleman, I. G., Worthington, H. V., Giedrys-Leeper, E. Tucker, R. J. Guided tissue regeneration for periodontal infra-bony defects. Cochrane Database Systematic Reviews, 19 April 2006 (2): CD001724 (review).
22. O'Leary, T. J., Drake, R. B. Naylor, J. E. (1972) The plaque control record. Journal of Periodontology 43, 38.
23. Palmer, R. M. Cortellini, P. (2008) Periodontal tissue engineering and regeneration. Journal of Clinical Periodontology (in press).
24. Tonetti, M., Pini-Prato, G. Cortellini, P. (1993b) Periodontal regeneration of human infrabony defects. IV. Determinants of the healing response. Journal of Periodontology 64, 934 940.
25. Tonetti, M., Pini-Prato, G. Cortellini, P. (1995) Effect of cigarette smoking on periodontal healing following GTR in infrabony defects. A preliminary retrospective study. Journal of Clinical Periodontology 22, 229 234.
26. Tonetti, M., Pini-Prato, G. Cortellini, P. (1996) Factors affecting the healing response of intrabony defects following guided tissue regeneration and access flap surgery. Journal of Clinical Periodontology 23, 548 556.
27. Tonetti, M. S., Fourmousis, I., Suvan, J., Cortellini, P., Bragger, U. Lang, N. P. (2004) Healing, post-operative morbidity and patient perception of outcomes following regenerative therapy of deep intrabony defects. Journal of Clinical Periodontology 31, 1092 1098.
28. Tonetti, M. S., Lang, N. P., Cortellini, P., Suvan, J. E., Adriaens, P., Dubravec, D., Fonzar, A., Fourmousis, J., Mayfield, L., Rossi, R., Silvestri, M., Tiedemann, C., Topoll, H., Vangsted, T. Walkamm, B. (2002) Enamel matrix proteins I the regenerative therapy of deep intrabony defects. A multicentre randomized controlled clinical trial. Journal of Clinical Periodontology 29, 317 325.
29. Tonetti, M. S., Pini-Prato, G. P., Williams, R. C. Cortellini, P. (1993a) Periodontal regeneration of human infrabony defects. III. Diagnostic strategies to detect bone gain. Journal of Periodontology 64, 269 277.
30. Wikesjo, U. M. Nilveus, R. (1990) Periodontal repair in dogs: effect of wound stabilisation on healing. Journal of Periodontology 61, 719 724.