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Volumn 2, Issue 1, 2009, Pages 12-27

Mitochondria, cellular stress resistance, somatic cell depletion and lifespan

Author keywords

Base excision repair; Glutathione peroxidase; Lifespan; Mitochondria; mtDNA; Mutation; Reactive oxygen species; Superoxide dismutase

Indexed keywords

GLUTATHIONE PEROXIDASE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN C; SUPEROXIDE DISMUTASE;

EID: 77949320611     PISSN: 18746098     EISSN: 18746128     Source Type: Journal    
DOI: 10.2174/1874609810902010012     Document Type: Article
Times cited : (19)

References (186)
  • 1
    • 0029093725 scopus 로고
    • Cellular oxygen consumption depends on body mass
    • Porter RK and Brand MD. Cellular oxygen consumption depends on body mass. Am J Physiol 269: R226-R228 (1995).
    • (1995) Am J Physiol , vol.269
    • Porter, R.K.1    Brand, M.D.2
  • 3
    • 0025801813 scopus 로고
    • Cardiomyopathy of the aging human heart: Myocyte loss and reactive cellular hypertrophy
    • Olivetti G, Melissari M, Capasso JM and Anversa P. Cardiomyopathy of the aging human heart: myocyte loss and reactive cellular hypertrophy. Circ Res 68: 1560-1568 (1991).
    • (1991) Circ Res , vol.68 , pp. 1560-1568
    • Olivetti, G.1    Melissari, M.2    Capasso, J.M.3    Anversa, P.4
  • 5
    • 0345714629 scopus 로고    scopus 로고
    • Quantitative analysis of retinal ganglion cell (RGC) loss in aging DBA/2NNia glaucomatous mice: Comparison with RGC loss in aging C57/BL6 mice
    • Danias J, Lee KC, Zamora M-F, Chen B, Shen F, Filippopoulos T, et al. Quantitative analysis of retinal ganglion cell (RGC) loss in aging DBA/2NNia glaucomatous mice: comparison with RGC loss in aging C57/BL6 mice. Invest Ophthalmol Visual Sci 44: 5151-5162 (2003).
    • (2003) Invest Ophthalmol Visual Sci , vol.44 , pp. 5151-5162
    • Danias, J.1    Lee, K.C.2    Zamora, M.-F.3    Chen, B.4    Shen, F.5    Filippopoulos, T.6
  • 6
    • 0036238915 scopus 로고    scopus 로고
    • The role of apoptosis in the normal aging brain, skeletal muscle and heart
    • Pollack M, Phaneuf S, Dirks A and Leeuwenburgh C. The role of apoptosis in the normal aging brain, skeletal muscle and heart. Ann NY Acad Sci 959: 93-107 (2006).
    • (2006) Ann NY Acad Sci , vol.959 , pp. 93-107
    • Pollack, M.1    Phaneuf, S.2    Dirks, A.3    Leeuwenburgh, C.4
  • 7
    • 29144506279 scopus 로고    scopus 로고
    • The naked mole-rat: A new long-living model for human aging research
    • Buffenstein R. The naked mole-rat: a new long-living model for human aging research. J Gerontol A Biol Sci Med Sci 60: 1369-1377 (2005).
    • (2005) J Gerontol a Biol Sci Med Sci , vol.60 , pp. 1369-1377
    • Buffenstein, R.1
  • 8
    • 0347359103 scopus 로고    scopus 로고
    • Reduced free-radical production and extreme longevity in the little brown bat (Myotis lucifugus) versus two nonflying mammals
    • Brunet-Rossinni AK. Reduced free-radical production and extreme longevity in the little brown bat (Myotis lucifugus) versus two nonflying mammals. Mech Ageing Dev 125: 11-20 (2004).
    • (2004) Mech Ageing Dev , vol.125 , pp. 11-20
    • Brunet-Rossinni, A.K.1
  • 9
    • 33751402849 scopus 로고    scopus 로고
    • Stress resistance in long-lived mouse models
    • Murakami S. Stress resistance in long-lived mouse models. Exp Gerontol 10: 1014-1019 (2006).
    • (2006) Exp Gerontol , vol.10 , pp. 1014-1019
    • Murakami, S.1
  • 10
    • 0026684532 scopus 로고
    • Selection on stress resistance increases longevity in Drosophila melanogaster
    • Rose MR, Vu LN, Park SU and Graves JL Jr. Selection on stress resistance increases longevity in Drosophila melanogaster. Exp Gerontol 27: 241-250 (1992).
    • (1992) Exp Gerontol , vol.27 , pp. 241-250
    • Rose, M.R.1    Vu, L.N.2    Park, S.U.3    Graves Jr., J.L.4
  • 11
    • 0037274713 scopus 로고    scopus 로고
    • Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity
    • Munoz MJ and Riddle DL. Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity. Genetics 163: 171-180 (2003).
    • (2003) Genetics , vol.163 , pp. 171-180
    • Munoz, M.J.1    Riddle, D.L.2
  • 12
    • 4644293695 scopus 로고    scopus 로고
    • The GH/IGF-axis and longevity
    • Holzenberger M. The GH/IGF-axis and longevity. Eur J Endocrinol 151: s23-s27 (2004).
    • (2004) Eur J Endocrinol , vol.151
    • Holzenberger, M.1
  • 13
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • Kenyon C, Chang J, Gensch E, Rudner A and Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 366: 461-464 (1993).
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 14
    • 0023831256 scopus 로고
    • A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility
    • Friedman DB and Johnson TE. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 118: 75-86 (1988).
    • (1988) Genetics , vol.118 , pp. 75-86
    • Friedman, D.B.1    Johnson, T.E.2
  • 15
    • 0027515616 scopus 로고
    • Aging and resistance to oxidative damage in Caenorhabditis elegans
    • Larsen, PL. Aging and resistance to oxidative damage in Caenorhabditis elegans. Proc Natl Acad Sci USA 90: 8905-8909 (1993).
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8905-8909
    • Larsen, P.L.1
  • 16
    • 0027197284 scopus 로고
    • Oxidative stress and ageing in Caenorhabditis elegans
    • Vanfleteren JR. Oxidative stress and ageing in Caenorhabditis elegans. Biochem J 292: 605-608 (1993).
    • (1993) Biochem J , vol.292 , pp. 605-608
    • Vanfleteren, J.R.1
  • 17
    • 0027945612 scopus 로고
    • Thermotolerance of a long-lived mutant of Caenorhabditis elegans
    • Lithgow GJ, White TM, Hinerfeld DA, Johnson TE. Thermotolerance of a long-lived mutant of Caenorhabditis elegans. J Gerontol 49: 270-276 (1994).
    • (1994) J Gerontol , vol.49 , pp. 270-276
    • Lithgow, G.J.1    White, T.M.2    Hinerfeld, D.A.3    Johnson, T.E.4
  • 18
    • 0035082093 scopus 로고    scopus 로고
    • Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans
    • Barsyte D, Lovejoy DA and Lithgow GJ. Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans. FASEB J 15: 627-634 (2001).
    • (2001) FASEB J , vol.15 , pp. 627-634
    • Barsyte, D.1    Lovejoy, D.A.2    Lithgow, G.J.3
  • 19
    • 0035815445 scopus 로고    scopus 로고
    • A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
    • Tatar M, Kopelman A, Epstein D, Tu MP, Yin CM and Garofalo RS. A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 292: 107-110 (2001).
    • (2001) Science , vol.292 , pp. 107-110
    • Tatar, M.1    Kopelman, A.2    Epstein, D.3    Tu, M.P.4    Yin, C.M.5    Garofalo, R.S.6
  • 20
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor 1 (Igf-1) and type 1 IGF receptor (igf1r)
    • Liu P, Baker J, Perkins AS, Robertson EJ and Efstratiadis A. Mice carrying null mutations of the genes encoding insulin-like growth factor 1 (Igf-1) and type 1 IGF receptor (igf1r). Cell 75: 59-72 (1993).
    • (1993) Cell , vol.75 , pp. 59-72
    • Liu, P.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 21
    • 0347664057 scopus 로고    scopus 로고
    • IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
    • Holzenberger M, Dupont J, Ducos B, Leneuve P, Géloën A, Even PC, et al. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 421: 182-187 (2003).
    • (2003) Nature , vol.421 , pp. 182-187
    • Holzenberger, M.1    Dupont, J.2    Ducos, B.3    Leneuve, P.4    Géloën, A.5    Even, P.C.6
  • 22
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • Blüher M, Kahn B and Kahn CR. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299: 572-574 (2003).
    • (2003) Science , vol.299 , pp. 572-574
    • Blüher, M.1    Kahn, B.2    Kahn, C.R.3
  • 23
    • 0033581704 scopus 로고    scopus 로고
    • The p66shc adaptor protein controls oxidative stress response and life span in mammals
    • Migliaccio E, Giorgio M, Mele S, Pelicci G, Reboldi T, Pandolfi PP, et al. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402: 309-313 (1999).
    • (1999) Nature , vol.402 , pp. 309-313
    • Migliaccio, E.1    Giorgio, M.2    Mele, S.3    Pelicci, G.4    Reboldi, T.5    Pandolfi, P.P.6
  • 24
    • 33846817351 scopus 로고    scopus 로고
    • Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc
    • Pinton P, Rimessi A, Marchi S, Orsini F, Migliaccio E, Giorgio M, et al. Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc. Science 315: 659-663 (2007).
    • (2007) Science , vol.315 , pp. 659-663
    • Pinton, P.1    Rimessi, A.2    Marchi, S.3    Orsini, F.4    Migliaccio, E.5    Giorgio, M.6
  • 25
    • 35348972430 scopus 로고    scopus 로고
    • Genetic links between diet and lifespan: Shared mechanisms from yeast to humans
    • Bishop NA and Guarente L. Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nat Rev Genet 8: 835-844 (2007).
    • (2007) Nat Rev Genet , vol.8 , pp. 835-844
    • Bishop, N.A.1    Guarente, L.2
  • 26
    • 33751246228 scopus 로고    scopus 로고
    • Does caloric restriction extend life in wild mice?
    • Harper JM, Leathers CW and Austad SN. Does caloric restriction extend life in wild mice? Aging Cell 5: 441-449 (2006).
    • (2006) Aging Cell , vol.5 , pp. 441-449
    • Harper, J.M.1    Leathers, C.W.2    Austad, S.N.3
  • 28
    • 33751407431 scopus 로고    scopus 로고
    • The longevity effect of dietary restriction in Caenorhabditis elegans
    • Houthoofd K and Vanfleteren JR. The longevity effect of dietary restriction in Caenorhabditis elegans. Exp Gerontol 41: 1026-1031 (2006).
    • (2006) Exp Gerontol , vol.41 , pp. 1026-1031
    • Houthoofd, K.1    Vanfleteren, J.R.2
  • 30
    • 33846445263 scopus 로고    scopus 로고
    • The functional costs and benefits of dietary restriction in Drosophila
    • Burger JM, Hwangbo DS, Corby-Harris V and Promislow DE. The functional costs and benefits of dietary restriction in Drosophila. Aging Cell 6: 63-71 (2007).
    • (2007) Aging Cell , vol.6 , pp. 63-71
    • Burger, J.M.1    Hwangbo, D.S.2    Corby-Harris, V.3    Promislow, D.E.4
  • 31
    • 0028921428 scopus 로고
    • Dietary calorie restriction in the Emory mouse: Effects on lifespan, eye lens cataract prevalence and progression, levels of ascorbate, glutathione, glucose, and glycohemoglobin, tail collagen breaktime, DNA and RNA oxidation, skin integrity, fecundity and cancer
    • Taylor A, Lipman RD, Jahngen-Hodge J, Palmer V, Smith D, Padhye N, et al. Dietary calorie restriction in the Emory mouse: effects on lifespan, eye lens cataract prevalence and progression, levels of ascorbate, glutathione, glucose, and glycohemoglobin, tail collagen breaktime, DNA and RNA oxidation, skin integrity, fecundity and cancer. Mech Ageing Dev 79: 33-57 (1995).
    • (1995) Mech Ageing Dev , vol.79 , pp. 33-57
    • Taylor, A.1    Lipman, R.D.2    Jahngen-Hodge, J.3    Palmer, V.4    Smith, D.5    Padhye, N.6
  • 32
    • 0037387956 scopus 로고    scopus 로고
    • Mechanisms of increased liver tissue repair and survival in diet-restricted rats treated with equitoxic doses of thioacetamide
    • Apte UM, Limaye PB, Desaiah D, Bucci TJ, Warbritton A and Mechendale HM. Mechanisms of increased liver tissue repair and survival in diet-restricted rats treated with equitoxic doses of thioacetamide. Toxicol Sci 72: 272-282 (2003).
    • (2003) Toxicol Sci , vol.72 , pp. 272-282
    • Apte, U.M.1    Limaye, P.B.2    Desaiah, D.3    Bucci, T.J.4    Warbritton, A.5    Mechendale, H.M.6
  • 34
    • 0026638153 scopus 로고
    • Mitotic activity in mice is suppressed by energy-restriction induced torpor
    • Koizumi A, Tsukada M, Wada Y, Masuda H and Weindruch R. Mitotic activity in mice is suppressed by energy-restriction induced torpor. J Nutr 122: 1446-1453 (1992).
    • (1992) J Nutr , vol.122 , pp. 1446-1453
    • Koizumi, A.1    Tsukada, M.2    Wada, Y.3    Masuda, H.4    Weindruch, R.5
  • 35
    • 3543017385 scopus 로고    scopus 로고
    • Natural hypometabolism during hibernation and daily torpor in mammals
    • Heldmaier G, Ortmann S and Elvert R. Natural hypometabolism during hibernation and daily torpor in mammals. Resp Physiol Neurobiol 141: 317-329 (2004).
    • (2004) Resp Physiol Neurobiol , vol.141 , pp. 317-329
    • Heldmaier, G.1    Ortmann, S.2    Elvert, R.3
  • 36
    • 0032972559 scopus 로고    scopus 로고
    • Positive correlation between mammalian life span and cellular resistance to stress
    • Kapahi P, Boulton ME, Kirkwood TB. Positive correlation between mammalian life span and cellular resistance to stress. Free Radic Biol Med 26: 495-500 (1999).
    • (1999) Free Radic Biol Med , vol.26 , pp. 495-500
    • Kapahi, P.1    Boulton, M.E.2    Kirkwood, T.B.3
  • 37
    • 33846417626 scopus 로고    scopus 로고
    • Skinderived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone
    • Harper JM, Salmon AB, Leiser SF, Galecki AT and Miller RA. Skinderived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone. Aging Cell. 6: 1-13 (2007).
    • (2007) Aging Cell , vol.6 , pp. 1-13
    • Harper, J.M.1    Salmon, A.B.2    Leiser, S.F.3    Galecki, A.T.4    Miller, R.A.5
  • 38
    • 29144506279 scopus 로고    scopus 로고
    • The naked mole-rat: A new long-living model for human aging research
    • Buffenstein R. The naked mole-rat: a new long-living model for human aging research. J Gerontol A Biol Sci Med Sci 60: 1369-1377 (2005).
    • (2005) J Gerontol a Biol Sci Med Sci , vol.60 , pp. 1369-1377
    • Buffenstein, R.1
  • 39
    • 44349135548 scopus 로고    scopus 로고
    • Fibroblasts from naked mole-rats are resistant to multiple from of cell injury, but sensitive to peroxide, ultraviolet light and endoplasmic reticulum stress
    • Salmon AB, Sadighi Akha AA, Buffenstein R, Miller RA. Fibroblasts from naked mole-rats are resistant to multiple from of cell injury, but sensitive to peroxide, ultraviolet light and endoplasmic reticulum stress. J Gerontol A Biol Sci Med Sci 63: 232-241 (2008).
    • (2008) J Gerontol a Biol Sci Med Sci , vol.63 , pp. 232-241
    • Salmon, A.B.1    Sadighi Akha, A.A.2    Buffenstein, R.3    Miller, R.A.4
  • 40
    • 33845388290 scopus 로고    scopus 로고
    • Comparison of endothelial function, O2 -· and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice
    • Labinskyy N, Csiszar A, Orosz Z, Smith K, Rivera A, Buffenstein R, et al. Comparison of endothelial function, O2 -· and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice. Am J Physiol Heart Circ Physiol 291: 2698-2704 (2006).
    • (2006) Am J Physiol Heart Circ Physiol , vol.291 , pp. 2698-2704
    • Labinskyy, N.1    Csiszar, A.2    Orosz, Z.3    Smith, K.4    Rivera, A.5    Buffenstein, R.6
  • 41
    • 13944276264 scopus 로고    scopus 로고
    • Life extension in the dwarf mouse
    • Bartke A and Brown-Borg H. Life extension in the dwarf mouse. Curr Top Dev Biol 63: 189-225 (2004).
    • (2004) Curr Top Dev Biol , vol.63 , pp. 189-225
    • Bartke, A.1    Brown-Borg, H.2
  • 42
    • 0042203536 scopus 로고    scopus 로고
    • Muliplex stress resistance in cells from long-lived dwarf mice
    • Murakami S, Salmon A and Miller RA. Muliplex stress resistance in cells from long-lived dwarf mice. FASEB J 17: 1565-1566 (2003).
    • (2003) FASEB J , vol.17 , pp. 1565-1566
    • Murakami, S.1    Salmon, A.2    Miller, R.A.3
  • 44
    • 33644796631 scopus 로고    scopus 로고
    • Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced in vitro growth arrest
    • Maynard SP and Miller RA. Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced in vitro growth arrest. Aging Cell 5: 89-96 (2006).
    • (2006) Aging Cell , vol.5 , pp. 89-96
    • Maynard, S.P.1    Miller, R.A.2
  • 45
    • 21044450084 scopus 로고    scopus 로고
    • Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress
    • Salmon AB, Murakami S, Bartke A, Kopchick J, Yasumura K and Miller RA. Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. Am J Physiol Endocrinol Metab 289: 23-29 (2005).
    • (2005) Am J Physiol Endocrinol Metab , vol.289 , pp. 23-29
    • Salmon, A.B.1    Murakami, S.2    Bartke, A.3    Kopchick, J.4    Yasumura, K.5    Miller, R.A.6
  • 46
    • 33750166237 scopus 로고    scopus 로고
    • Correlated resistance to glucose deprivation and cytotoxic agents in fibroblast cell lines from long-lived pituitary dwarf mice
    • Leiser SF, Salmon AB and Miller RA. Correlated resistance to glucose deprivation and cytotoxic agents in fibroblast cell lines from long-lived pituitary dwarf mice. Mech Ageing Dev 127: 821-829 (2006).
    • (2006) Mech Ageing Dev , vol.127 , pp. 821-829
    • Leiser, S.F.1    Salmon, A.B.2    Miller, R.A.3
  • 47
    • 33846417626 scopus 로고    scopus 로고
    • Skinderived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone
    • Harper JM, Salmon AB, Leiser SF, Galecki AT and Miller RA. Skinderived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone. Aging Cell 6: 1-13 (2007).
    • (2007) Aging Cell , vol.6 , pp. 1-13
    • Harper, J.M.1    Salmon, A.B.2    Leiser, S.F.3    Galecki, A.T.4    Miller, R.A.5
  • 50
    • 0037430971 scopus 로고    scopus 로고
    • Oxidative stress in cell culture: An under-appreciated problem?
    • Halliwell B. Oxidative stress in cell culture: an under-appreciated problem? FEBS Lett 540: 3-6 (2003).
    • (2003) FEBS Lett , vol.540 , pp. 3-6
    • Halliwell, B.1
  • 51
    • 4043147798 scopus 로고    scopus 로고
    • Mitochondrial superoxide: Production, biological effects, and activation of uncoupling proteins
    • Brand MD, Affourtit C, Esteves TC, Green K, Lambert AJ, Miwa S, et al. Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins. Free Radic Biol Med 37: 755-767 (2004).
    • (2004) Free Radic Biol Med , vol.37 , pp. 755-767
    • Brand, M.D.1    Affourtit, C.2    Esteves, T.C.3    Green, K.4    Lambert, A.J.5    Miwa, S.6
  • 52
    • 0024323120 scopus 로고
    • Superoxide anion radical production in different animal species
    • Sohal RS, Svensson I, Sohal BH and Brunk UT. Superoxide anion radical production in different animal species. Mech Ageing Dev 49: 129-135 (1989).
    • (1989) Mech Ageing Dev , vol.49 , pp. 129-135
    • Sohal, R.S.1    Svensson, I.2    Sohal, B.H.3    Brunk, U.T.4
  • 53
    • 0025363588 scopus 로고
    • Hydrogen peroxide production by liver mitochondria in different species
    • Sohal RS, Svensson I and Brunk UT. Hydrogen peroxide production by liver mitochondria in different species. Mech Ageing Dev 53: 209-215 (1990).
    • (1990) Mech Ageing Dev , vol.53 , pp. 209-215
    • Sohal, R.S.1    Svensson, I.2    Brunk, U.T.3
  • 54
    • 0027365312 scopus 로고
    • Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species
    • Ku H-H, Brunk UT and Sohal RS. Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. Free Radic Biol Med 15: 621-627 (1993).
    • (1993) Free Radic Biol Med , vol.15 , pp. 621-627
    • Ku, H.-H.1    Brunk, U.T.2    Sohal, R.S.3
  • 55
    • 0036829433 scopus 로고    scopus 로고
    • Rate of generation of oxidative stress-related damage and animal longevity
    • Barja G. Rate of generation of oxidative stress-related damage and animal longevity. Free Radic Biol Med 33: 1167-1172 (2002).
    • (2002) Free Radic Biol Med , vol.33 , pp. 1167-1172
    • Barja, G.1
  • 56
    • 34548617735 scopus 로고    scopus 로고
    • Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms
    • Lambert AJ, Boysen HM, Buckingham JA, Yang T, Podlutsky A, Austad SN, et al. Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms. Aging Cell 6: 607-618 (2007).
    • (2007) Aging Cell , vol.6 , pp. 607-618
    • Lambert, A.J.1    Boysen, H.M.2    Buckingham, J.A.3    Yang, T.4    Podlutsky, A.5    Austad, S.N.6
  • 57
    • 24344480299 scopus 로고    scopus 로고
    • Correlations between physiology and lifespan-two widely ignored problems with comparative studies
    • Speakman JR. Correlations between physiology and lifespan-two widely ignored problems with comparative studies. Aging Cell 4: 167-175 (2005).
    • (2005) Aging Cell , vol.4 , pp. 167-175
    • Speakman, J.R.1
  • 58
    • 0036588425 scopus 로고    scopus 로고
    • Oxygen modulates the growth of skin fibroblasts. In Vitro
    • Balin AK, Pratt L. Oxygen modulates the growth of skin fibroblasts. In Vitro Cell Dev Biol Anim 38: 305-310 (2002).
    • (2002) Cell Dev Biol Anim , vol.38 , pp. 305-310
    • Balin, A.K.1    Pratt, L.2
  • 59
    • 0032052209 scopus 로고    scopus 로고
    • Mitochondrial oxygen affinity, respiratory flux control and excess capacity of cytochrome c oxidase
    • Gnaiger E, Lassnig B, Kuznetsov A, Rieger G, Margreiter R. Mitochondrial oxygen affinity, respiratory flux control and excess capacity of cytochrome c oxidase. J Exp Biol 201: 1129-1139, (1998).
    • (1998) J Exp Biol , vol.201 , pp. 1129-1139
    • Gnaiger, E.1    Lassnig, B.2    Kuznetsov, A.3    Rieger, G.4    Margreiter, R.5
  • 60
    • 28644442428 scopus 로고    scopus 로고
    • SOD2 overexpression: Enhanced mitochondrial tolerance but absence of effect on UCP activity
    • Silva JP, Shabalina IG, Dufour E, Petrovic N, Backlund EC, Hultenby K, et al. SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity. EMBO J 24: 4061-4070 (2005).
    • (2005) EMBO J , vol.24 , pp. 4061-4070
    • Silva, J.P.1    Shabalina, I.G.2    Dufour, E.3    Petrovic, N.4    Backlund, E.C.5    Hultenby, K.6
  • 61
    • 0030915483 scopus 로고    scopus 로고
    • Mitochondrial decay in hepatocytes from old rats: Membrane potential declines, heterogeneity and oxidants increase
    • Hagen TM, Yowe DL, Bartholomew JC, Wehr CM, Do KL, Park JY, et al. Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase. Proc Natl Acad Sci USA 94: 3064-3069 (1997).
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3064-3069
    • Hagen, T.M.1    Yowe, D.L.2    Bartholomew, J.C.3    Wehr, C.M.4    Do, K.L.5    Park, J.Y.6
  • 62
    • 0032910371 scopus 로고    scopus 로고
    • The effect of aging and an oxidative stress on peroxide levels and the mitochondrial membrane potential in isolated rat hepatocytes
    • Cavazzoni M, Barogi S, Baracca A, Castelli GP and Lenaz G. The effect of aging and an oxidative stress on peroxide levels and the mitochondrial membrane potential in isolated rat hepatocytes. FEBS Lett 449: 53-56 (1999).
    • (1999) FEBS Lett , vol.449 , pp. 53-56
    • Cavazzoni, M.1    Barogi, S.2    Baracca, A.3    Castelli, G.P.4    Lenaz, G.5
  • 64
    • 0035914342 scopus 로고    scopus 로고
    • Subcellular distribution of superoxide dismutases (SOD) in rat liver
    • Okado-Matsumoto A and Fridovich I. Subcellular distribution of superoxide dismutases (SOD) in rat liver. J Biol Chem 276: 38388-38393 (2001).
    • (2001) J Biol Chem , vol.276 , pp. 38388-38393
    • Okado-Matsumoto, A.1    Fridovich, I.2
  • 65
    • 0019073929 scopus 로고
    • The metabolic fate of mitochondrial hydrogen peroxide
    • Nohl H, Jordan W. The metabolic fate of mitochondrial hydrogen peroxide. Eur J Biochem 111: 203-210 (1980).
    • (1980) Eur J Biochem , vol.111 , pp. 203-210
    • Nohl, H.1    Jordan, W.2
  • 66
    • 0034055373 scopus 로고    scopus 로고
    • Cellular and subcellular localization of catalase in the heart of transgenic mice
    • Zhou Z, Kang YJ. Cellular and subcellular localization of catalase in the heart of transgenic mice. J Histochem Cytochem 48: 585-594 (2000).
    • (2000) J Histochem Cytochem , vol.48 , pp. 585-594
    • Zhou, Z.1    Kang, Y.J.2
  • 67
    • 0037438730 scopus 로고    scopus 로고
    • Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells
    • Imai H and Nakagawa Y. Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells. Free Radic Biol Med 34: 145-169 (2003).
    • (2003) Free Radic Biol Med , vol.34 , pp. 145-169
    • Imai, H.1    Nakagawa, Y.2
  • 68
    • 37249016870 scopus 로고    scopus 로고
    • A measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans
    • Yang W, Li J and Hekimi S. A measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans. Genetics 177: 2063-2074 (2007).
    • (2007) Genetics , vol.177 , pp. 2063-2074
    • Yang, W.1    Li, J.2    Hekimi, S.3
  • 69
    • 34447528668 scopus 로고    scopus 로고
    • Type 5 adnylyl cyclase disruption increases longevity and protects against stress
    • Yan L, Vatner DE, O'Connor JP, Ivessa A, Chen W, Hirotani S, et al. Type 5 adnylyl cyclase disruption increases longevity and protects against stress. Cell 130: 247-258 (2007).
    • (2007) Cell , vol.130 , pp. 247-258
    • Yan, L.1    Vatner, D.E.2    O'Connor, J.P.3    Ivessa, A.4    Chen, W.5    Hirotani, S.6
  • 70
    • 25144510360 scopus 로고    scopus 로고
    • Antioxidants do not explain the disparate longevity between mice and the longestliving rodent, the naked mole-rat
    • Andziak B, O'Connor TP and Buffenstein R. Antioxidants do not explain the disparate longevity between mice and the longestliving rodent, the naked mole-rat. Mech Ageing Dev 126: 1206-1212 (2005).
    • (2005) Mech Ageing Dev , vol.126 , pp. 1206-1212
    • Andziak, B.1    O'Connor, T.P.2    Buffenstein, R.3
  • 71
    • 37349000601 scopus 로고    scopus 로고
    • Correlation of mitochondrial superoxide dismutase and DNA polymerase beta in mammalian dermal fibroblasts with species maximal lifespan
    • Brown MF and Stuart JA. Correlation of mitochondrial superoxide dismutase and DNA polymerase beta in mammalian dermal fibroblasts with species maximal lifespan. Mech Ageing Dev 128: 696-705 (2007).
    • (2007) Mech Ageing Dev , vol.128 , pp. 696-705
    • Brown, M.F.1    Stuart, J.A.2
  • 72
    • 4644360633 scopus 로고    scopus 로고
    • Oxidants, antioxidants and the ischemic brain
    • Warner DS, Sheng H and Batinic-Haberle I. Oxidants, antioxidants and the ischemic brain. J Exp Biol 207: 3221-3231 (2004).
    • (2004) J Exp Biol , vol.207 , pp. 3221-3231
    • Warner, D.S.1    Sheng, H.2    Batinic-Haberle, I.3
  • 73
    • 25144478337 scopus 로고    scopus 로고
    • Biochemical dysfunction in heart mitochondria exposed to ischaemia and reperfusion
    • Solaini G and Harris DA. Biochemical dysfunction in heart mitochondria exposed to ischaemia and reperfusion. Biochem J 390: 377-394 (2005).
    • (2005) Biochem J , vol.390 , pp. 377-394
    • Solaini, G.1    Harris, D.A.2
  • 74
    • 38349053821 scopus 로고    scopus 로고
    • Molecular mechanisms of oxidative stress resistance induced by resveratrol: Specific and progressive induction of MnSOD
    • Robb EL, Page MM, Wiens BE, Stuart JA. Molecular mechanisms of oxidative stress resistance induced by resveratrol: Specific and progressive induction of MnSOD. Biochem Biophys Res Commun 367: 406-412 (2008).
    • (2008) Biochem Biophys Res Commun , vol.367 , pp. 406-412
    • Robb, E.L.1    Page, M.M.2    Wiens, B.E.3    Stuart, J.A.4
  • 76
    • 0029838063 scopus 로고    scopus 로고
    • Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice
    • Lebovitz RM, Zhang H, Vogel H, Cartwright Jr J, Dionne L, Lu N, et al. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proc Natl Sci Acad USA 93: 9782-9787 (1996).
    • (1996) Proc Natl Sci Acad USA , vol.93 , pp. 9782-9787
    • Lebovitz, R.M.1    Zhang, H.2    Vogel, H.3    Cartwright, J.4    Dionne, L.5    Lu, N.6
  • 77
    • 0032782364 scopus 로고    scopus 로고
    • The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
    • Honda Y and Honda S. The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J 13: 1385-1393 (1999).
    • (1999) FASEB J , vol.13 , pp. 1385-1393
    • Honda, Y.1    Honda, S.2
  • 78
    • 0042092531 scopus 로고    scopus 로고
    • Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
    • Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, et al. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424: 277-283 (2003).
    • (2003) Nature , vol.424 , pp. 277-283
    • Murphy, C.T.1    McCarroll, S.A.2    Bargmann, C.I.3    Fraser, A.4    Kamath, R.S.5    Ahringer, J.6
  • 79
    • 0030667197 scopus 로고    scopus 로고
    • Cloning, expression, and characterization of two manganese superoxide dismutases from Caenorhabditis elegans
    • Hunter T, Bannister WH and Hunter GJ. Cloning, expression, and characterization of two manganese superoxide dismutases from Caenorhabditis elegans. J Biol Chem 272: 28652-28659 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 28652-28659
    • Hunter, T.1    Bannister, W.H.2    Hunter, G.J.3
  • 80
    • 0030606605 scopus 로고    scopus 로고
    • Cloning, sequencing and mapping of a manganese superoxide dismutase gene of the nematode Caenorhabditis elegans
    • Suzuki N, Inokuma TK, Yasuda K and Ishii N. Cloning, sequencing and mapping of a manganese superoxide dismutase gene of the nematode Caenorhabditis elegans. DNA Res 3: 171-174 (1996).
    • (1996) DNA Res , vol.3 , pp. 171-174
    • Suzuki, N.1    Inokuma, T.K.2    Yasuda, K.3    Ishii, N.4
  • 81
    • 43649105922 scopus 로고    scopus 로고
    • Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like control in Caenorhabditis elegans
    • Honda Y, Tanaka M and Honda S. Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like control in Caenorhabditis elegans. Exp Gerontol 43: 520-529 (2008).
    • (2008) Exp Gerontol , vol.43 , pp. 520-529
    • Honda, Y.1    Tanaka, M.2    Honda, S.3
  • 82
    • 0035989388 scopus 로고    scopus 로고
    • Induced overexpression of mitochondrial Mn-superoxide dismutase extends the lifespan of adult Drosophila melanogaster
    • Sun J, Folk D, Bradley TJ and Tower J. Induced overexpression of mitochondrial Mn-superoxide dismutase extends the lifespan of adult Drosophila melanogaster. Genetics 161: 661-672 (2002).
    • (2002) Genetics , vol.161 , pp. 661-672
    • Sun, J.1    Folk, D.2    Bradley, T.J.3    Tower, J.4
  • 83
    • 0032908347 scopus 로고    scopus 로고
    • FLP recombinase-mediated induction of Cu/Znsuperoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies
    • Sun J and Tower J. FLP recombinase-mediated induction of Cu/Znsuperoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies. Mol Cell Biol 19: 216-228, (1999).
    • (1999) Mol Cell Biol , vol.19 , pp. 216-228
    • Sun, J.1    Tower, J.2
  • 84
    • 0035851122 scopus 로고    scopus 로고
    • A fraction of yeast CuZn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria
    • Sturtz LA, Diekert K, Jensen LT, Lill R and Culotta VC. A fraction of yeast CuZn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. J Biol Chem 276: 38084-38089 (2001).
    • (2001) J Biol Chem , vol.276 , pp. 38084-38089
    • Sturtz, L.A.1    Diekert, K.2    Jensen, L.T.3    Lill, R.4    Culotta, V.C.5
  • 85
    • 0036509487 scopus 로고    scopus 로고
    • Association of CuZn-type superoxide dismutase with mitochondria and peroxisomes
    • Kira Y, Sato EF and Inoue M. Association of CuZn-type superoxide dismutase with mitochondria and peroxisomes. Arch Biochem Biophys 399: 96-102 (2002).
    • (2002) Arch Biochem Biophys , vol.399 , pp. 96-102
    • Kira, Y.1    Sato, E.F.2    Inoue, M.3
  • 86
    • 33947629136 scopus 로고    scopus 로고
    • Superoxide dismutase activities in long-lived Drosophila melanogaster females: Chico1 genotypes and dietary dilution
    • Kabil H, Partridge L, Harshman LG. Superoxide dismutase activities in long-lived Drosophila melanogaster females: chico1 genotypes and dietary dilution. Biogerontology 8: 201-208 (2007).
    • (2007) Biogerontology , vol.8 , pp. 201-208
    • Kabil, H.1    Partridge, L.2    Harshman, L.G.3
  • 87
    • 0023130150 scopus 로고
    • Assaying for superoxide dismutase activity: Some large consequences of minor changes in conditions
    • Beyer WF Jr. and Fridovich I. Assaying for superoxide dismutase activity: Some large consequences of minor changes in conditions. Anal Biochem 161: 559-566 (1987).
    • (1987) Anal Biochem , vol.161 , pp. 559-566
    • Beyer Jr., W.F.1    Fridovich, I.2
  • 88
    • 0024402834 scopus 로고
    • An assay for superoxide dismutase activity in mammalian tissue homogenates
    • Spitz DR and Oberley LW. An assay for superoxide dismutase activity in mammalian tissue homogenates. Anal Biochem 179: 8-18 (1989).
    • (1989) Anal Biochem , vol.179 , pp. 8-18
    • Spitz, D.R.1    Oberley, L.W.2
  • 89
    • 0028827252 scopus 로고
    • Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
    • Li Y, Huang T-T, Carlson EJ, Melov S, Ursell PC, Olson JL, et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 11: 376-381 (1995).
    • (1995) Nat Genet , vol.11 , pp. 376-381
    • Li, Y.1    Huang, T.-T.2    Carlson, E.J.3    Melov, S.4    Ursell, P.C.5    Olson, J.L.6
  • 90
    • 12144288373 scopus 로고    scopus 로고
    • Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
    • Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, et al. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol Genomics 16: 29-37 (2003).
    • (2003) Physiol Genomics , vol.16 , pp. 29-37
    • van Remmen, H.1    Ikeno, Y.2    Hamilton, M.3    Pahlavani, M.4    Wolf, N.5    Thorpe, S.R.6
  • 91
    • 0032561328 scopus 로고    scopus 로고
    • Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice
    • Williams MD, Van Remmen H, Conrad CC, Huang T-T, Epstein CJ and Richardson A. Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice. J Biol Chem 273: 28510-28515 (1998).
    • (1998) J Biol Chem , vol.273 , pp. 28510-28515
    • Williams, M.D.1    van Remmen, H.2    Conrad, C.C.3    Huang, T.-T.4    Epstein, C.J.5    Richardson, A.6
  • 93
    • 33749234188 scopus 로고    scopus 로고
    • A new paradigm: Manganese superoxide dismutase influences the production of H2O2 in cells and thereby their biological state
    • Buettner GR, Ng CF, Wang M, Rodgers VG, Schafer FQ. A new paradigm: manganese superoxide dismutase influences the production of H2O2 in cells and thereby their biological state. Free Radic Biol Med 8: 1338-1350 (2006).
    • (2006) Free Radic Biol Med , vol.8 , pp. 1338-1350
    • Buettner, G.R.1    Ng, C.F.2    Wang, M.3    Rodgers, V.G.4    Schafer, F.Q.5
  • 95
    • 34948853679 scopus 로고    scopus 로고
    • Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis
    • Ran Q, Liang H, Ikeno Y, Qi W, Prolla TA, Roberts LJ 2nd, et al. Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis, J. Gerontol 62: 932-942 (2007).
    • (2007) J. Gerontol , vol.62 , pp. 932-942
    • Ran, Q.1    Liang, H.2    Ikeno, Y.3    Qi, W.4    Prolla, T.A.5    Roberts 2nd, L.J.6
  • 96
    • 21144434217 scopus 로고    scopus 로고
    • Extension of murine life span by overexpression of catalase targeted to mitochondria
    • Schriner SE, Linford NJ, Martin GM, Treuting P, Ogburn CE, Emond M, et al. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 308: 1909-1911 (2005).
    • (2005) Science , vol.308 , pp. 1909-1911
    • Schriner, S.E.1    Linford, N.J.2    Martin, G.M.3    Treuting, P.4    Ogburn, C.E.5    Emond, M.6
  • 97
    • 0032504657 scopus 로고    scopus 로고
    • Role of mitochondria in oxidative stress and ageing
    • Lenaz G. Role of mitochondria in oxidative stress and ageing. Biochim Biophys Acta 1366: 53-67 (1998).
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 53-67
    • Lenaz, G.1
  • 98
    • 0025864512 scopus 로고
    • An integrated theory of aging as the result of mitochondrial-DNA mutation in differentiated cells
    • Miquel J. An integrated theory of aging as the result of mitochondrial-DNA mutation in differentiated cells. Arch Gerontol Geriatr 12: 99-117 (1991).
    • (1991) Arch Gerontol Geriatr , vol.12 , pp. 99-117
    • Miquel, J.1
  • 99
    • 0037305921 scopus 로고    scopus 로고
    • Oxygen consumption rates and oxygen concentration in nolt-4 cells and their mtDNA depleted (rho0) mutants
    • Shen J, Khan N, Lewis LD, Armand R, Grinberg O, Demidenko E, et al. Oxygen consumption rates and oxygen concentration in nolt-4 cells and their mtDNA depleted (rho0) mutants. Biophys J 84: 1291-1298 (2003).
    • (2003) Biophys J , vol.84 , pp. 1291-1298
    • Shen, J.1    Khan, N.2    Lewis, L.D.3    Armand, R.4    Grinberg, O.5    Demidenko, E.6
  • 100
    • 0036935437 scopus 로고    scopus 로고
    • Maintenance of mitochondrial DNA integrity: Repair and degradation
    • Kang H and Hamaski N. Maintenance of mitochondrial DNA integrity: repair and degradation. Curr Genet 4: 311-322 (2002).
    • (2002) Curr Genet , vol.4 , pp. 311-322
    • Kang, H.1    Hamaski, N.2
  • 102
    • 0014690248 scopus 로고
    • Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat
    • Gross HJ, Getz GS and Rabinowitz M. Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat. J Biol Chem 244: 1552-1562 (1969).
    • (1969) J Biol Chem , vol.244 , pp. 1552-1562
    • Gross, H.J.1    Getz, G.S.2    Rabinowitz, M.3
  • 104
    • 4444339833 scopus 로고    scopus 로고
    • Oxidative DNA damage and diseases: Induction, repair and significance
    • Evans MD, Dizdaroglu M and Cooke MS. Oxidative DNA damage and diseases: induction, repair and significance. Mutat Res 567: 1-61 (2004).
    • (2004) Mutat Res , vol.567 , pp. 1-61
    • Evans, M.D.1    Dizdaroglu, M.2    Cooke, M.S.3
  • 105
    • 0033972463 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals
    • Barja G and Herrero A. Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals. FASEB J 14: 312-318 (2000).
    • (2000) FASEB J , vol.14 , pp. 312-318
    • Barja, G.1    Herrero, A.2
  • 107
    • 1042278890 scopus 로고    scopus 로고
    • Are we sure we know how to measure 8-oxo-7,8-dihydroguanine in DNA from human cells?
    • Collins AR, Cadet J, Möller L, Poulsen HE, Viña J. Are we sure we know how to measure 8-oxo-7,8-dihydroguanine in DNA from human cells? Arch Biochem Biophys 423: 57-65 (2004).
    • (2004) Arch Biochem Biophys , vol.423 , pp. 57-65
    • Collins, A.R.1    Cadet, J.2    Möller, L.3    Poulsen, H.E.4    Viña, J.5
  • 108
    • 0023811053 scopus 로고
    • Normal oxidative damage to mitochondrial and nuclear DNA is extensive
    • Richter C, Park JW and Ames BN. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc Natl Acad Sci USA 85: 6465-6467 (1988).
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6465-6467
    • Richter, C.1    Park, J.W.2    Ames, B.N.3
  • 109
    • 0000825475 scopus 로고
    • The absence of pyrimidine dimer repair mechanism in mammalian mitochondria
    • Clayton DA, Doda JN and Friedberg EC. The absence of pyrimidine dimer repair mechanism in mammalian mitochondria. Proc Natl Acad Sci USA 71: 2777-2778 (1974).
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 2777-2778
    • Clayton, D.A.1    Doda, J.N.2    Friedberg, E.C.3
  • 110
  • 112
    • 0027438888 scopus 로고
    • Repair of oxidative damage within the mitochondrial DNA of RINr 38 cells
    • Driggers WJ, LeDoux SP and Wilson GL. Repair of oxidative damage within the mitochondrial DNA of RINr 38 cells. J Biol Chem 268: 220242-22045 (1993).
    • (1993) J Biol Chem , vol.268 , pp. 42-45
    • Driggers, W.J.1    Ledoux, S.P.2    Wilson, G.L.3
  • 113
    • 0022373294 scopus 로고
    • Purification of nuclear and mitochondrial uracil-DNA glycosylase from rat liver. Identification of two distinct subcellular forms
    • Domena JD and Mosbaugh DW. Purification of nuclear and mitochondrial uracil-DNA glycosylase from rat liver. Identification of two distinct subcellular forms. Biochemistry 24: 7320-7328 (1985).
    • (1985) Biochemistry , vol.24 , pp. 7320-7328
    • Domena, J.D.1    Mosbaugh, D.W.2
  • 114
    • 0028980982 scopus 로고
    • Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of enzyme in mitochondria
    • Kang D, Nishida J, Iyama A, Nakabeppu Y, Furuichi M, Fujiwara T, et al. Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of enzyme in mitochondria. J Biol Chem 270: 14659-14665 (1995).
    • (1995) J Biol Chem , vol.270 , pp. 14659-14665
    • Kang, D.1    Nishida, J.2    Iyama, A.3    Nakabeppu, Y.4    Furuichi, M.5    Fujiwara, T.6
  • 115
    • 18444385675 scopus 로고    scopus 로고
    • Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols
    • Takao M, Kanno S, Shiromoto T, Hasegawa R, Ide H, Ikeda S, et al. Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols. EMBO J 21: 3486-3493 (2002).
    • (2002) EMBO J , vol.21 , pp. 3486-3493
    • Takao, M.1    Kanno, S.2    Shiromoto, T.3    Hasegawa, R.4    Ide, H.5    Ikeda, S.6
  • 116
    • 0036904660 scopus 로고    scopus 로고
    • Rat MYH, a glycosylase for repair of oxidative damaged DNA has brain-specific isoforms that localize to neuronal mitochondria
    • Englander EW, Hu Z, Sharma A, Lee HM, Wu ZH and Greeley GH. Rat MYH, a glycosylase for repair of oxidative damaged DNA has brain-specific isoforms that localize to neuronal mitochondria. J Neurochem 83: 1471-1480 (2002).
    • (2002) J Neurochem , vol.83 , pp. 1471-1480
    • Englander, E.W.1    Hu, Z.2    Sharma, A.3    Lee, H.M.4    Wu, Z.H.5    Greeley, G.H.6
  • 117
    • 0035878869 scopus 로고    scopus 로고
    • Repiar of 8-oxodeoxyguanosine lesions in mitochondrial DNA depends on the oxoguanine DNA glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial DNA of OGG-1 defective mice
    • de Souza-Pinto NC, Eide L, Hogue BA, Thybo T, Stevnsner T, Seeberg E, et al. Repiar of 8-oxodeoxyguanosine lesions in mitochondrial DNA depends on the oxoguanine DNA glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial DNA of OGG-1 defective mice. Cancer Res 61: 5378-5381 (2001).
    • (2001) Cancer Res , vol.61 , pp. 5378-5381
    • de Souza-Pinto, N.C.1    Eide, L.2    Hogue, B.A.3    Thybo, T.4    Stevnsner, T.5    Seeberg, E.6
  • 118
    • 0033539610 scopus 로고    scopus 로고
    • Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
    • Klungland A, Rosewell I, Hollenbach S, Larsen E, Daly G, Epe B, et al. Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc Natl Acad Sci USA 96: 13300-13305 (1999).
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13300-13305
    • Klungland, A.1    Rosewell, I.2    Hollenbach, S.3    Larsen, E.4    Daly, G.5    Epe, B.6
  • 119
    • 13844266312 scopus 로고    scopus 로고
    • No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA
    • Stuart JA, Bourque BM, de Souza-Pinto NC and Bohr VA. No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA. Free Radic Biol Med 38: 737-745 (2005).
    • (2005) Free Radic Biol Med , vol.38 , pp. 737-745
    • Stuart, J.A.1    Bourque, B.M.2    de Souza-Pinto, N.C.3    Bohr, V.A.4
  • 120
    • 0033568311 scopus 로고    scopus 로고
    • Single-nucleotide patch base excision repair of uracil by mitochondrial protein extracts
    • Stierum RH, Dianov GL and Bohr VA. Single-nucleotide patch base excision repair of uracil by mitochondrial protein extracts. Nucleic Acids Res 27: 3712-3719 (1999).
    • (1999) Nucleic Acids Res , vol.27 , pp. 3712-3719
    • Stierum, R.H.1    Dianov, G.L.2    Bohr, V.A.3
  • 121
    • 3042766227 scopus 로고    scopus 로고
    • Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase
    • Endres M, Biniszkiewicz D, Sobol RW, Harms C, Ahmadi M, Lipski A, et al. Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. J Clin Invest 113: 1711-1721 (2004).
    • (2004) J Clin Invest , vol.113 , pp. 1711-1721
    • Endres, M.1    Biniszkiewicz, D.2    Sobol, R.W.3    Harms, C.4    Ahmadi, M.5    Lipski, A.6
  • 122
    • 34247173885 scopus 로고    scopus 로고
    • Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress
    • Akbari M, Otterlei M, Pena-Diaz J and Krokan HE. Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress. Neuroscience 145: 1201-1212 (2007).
    • (2007) Neuroscience , vol.145 , pp. 1201-1212
    • Akbari, M.1    Otterlei, M.2    Pena-Diaz, J.3    Krokan, H.E.4
  • 123
    • 40649109989 scopus 로고    scopus 로고
    • Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis
    • Akbari M, Visnes T, Krokan HE and Otterlei M. Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis. DNA Repair 7: 605-616 (2008).
    • (2008) DNA Repair , vol.7 , pp. 605-616
    • Akbari, M.1    Visnes, T.2    Krokan, H.E.3    Otterlei, M.4
  • 124
    • 13644261745 scopus 로고    scopus 로고
    • Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic
    • Kachhap S and Singh KK. Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic. Mol Cancer 1: 3-32 (2004).
    • (2004) Mol Cancer , vol.1 , pp. 3-32
    • Kachhap, S.1    Singh, K.K.2
  • 125
    • 34147137976 scopus 로고    scopus 로고
    • Folate deprivation promotes mitochondrial oxidative decay: DNA large deletions, cytochrome c oxidase dysfunction, membrane depolarization and superoxide overproduction in rat liver
    • Chang CM, Yu CC, Lu HT, Chou YF, Huang RF. Folate deprivation promotes mitochondrial oxidative decay: DNA large deletions, cytochrome c oxidase dysfunction, membrane depolarization and superoxide overproduction in rat liver. Br J Nutr 97: 855-863 (2007).
    • (2007) Br J Nutr , vol.97 , pp. 855-863
    • Chang, C.M.1    Yu, C.C.2    Lu, H.T.3    Chou, Y.F.4    Huang, R.F.5
  • 126
    • 0034535899 scopus 로고    scopus 로고
    • Enhanced mitochondrial DNA repair and cellular survival after oxidative stress by targeting the human 8-oxoguanine glycosylase repair enzyme to mitochondria
    • Dobson AW, Xu Y, Kelley MR, LeDoux SP and Wilson GL. Enhanced mitochondrial DNA repair and cellular survival after oxidative stress by targeting the human 8-oxoguanine glycosylase repair enzyme to mitochondria. J Biol Chem 275: 37518-37523 (2000).
    • (2000) J Biol Chem , vol.275 , pp. 37518-37523
    • Dobson, A.W.1    Xu, Y.2    Kelley, M.R.3    Ledoux, S.P.4    Wilson, G.L.5
  • 127
    • 45949093288 scopus 로고    scopus 로고
    • Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from 2-methoxyestradiol-inducedmitochondria- depenedent apoptosis
    • Chatterjee A, Chang X, Nagpal JK, Chang S, Upadhyay S, Califano J, et al. Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from 2-methoxyestradiol-inducedmitochondria- depenedent apoptosis. Oncogene 27: 3710-3720 (2008).
    • (2008) Oncogene , vol.27 , pp. 3710-3720
    • Chatterjee, A.1    Chang, X.2    Nagpal, J.K.3    Chang, S.4    Upadhyay, S.5    Califano, J.6
  • 128
    • 0038458979 scopus 로고    scopus 로고
    • Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadioneinduced oxidative stress
    • Druzhyna NM, Hollensworth SB, Kelley MR, Wilson SP and LeDoux SP. Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadioneinduced oxidative stress. Glia 42: 370-378 (2003).
    • (2003) Glia , vol.42 , pp. 370-378
    • Druzhyna, N.M.1    Hollensworth, S.B.2    Kelley, M.R.3    Wilson, S.P.4    Ledoux, S.P.5
  • 129
    • 20444430445 scopus 로고    scopus 로고
    • Cytokines induce nitric oxide-mediated mtDNA damage and apoptosis in oligodendrocytes. Protective role of targeting 8- oxoguanine glycosylase to mitochondria
    • Druzhyna NM, Musiyenko SL, Wilson GL and LeDoux SP. Cytokines induce nitric oxide-mediated mtDNA damage and apoptosis in oligodendrocytes. Protective role of targeting 8- oxoguanine glycosylase to mitochondria. J Biol Chem 280: 21673-21679 (2005).
    • (2005) J Biol Chem , vol.280 , pp. 21673-21679
    • Druzhyna, N.M.1    Musiyenko, S.L.2    Wilson, G.L.3    Ledoux, S.P.4
  • 130
    • 0037309710 scopus 로고    scopus 로고
    • Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methypurine DNA glycosylase in mitochondria leads to enhanced cell killing
    • Fishel ML, Seo YR, Smith ML and Kelley MR. Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methypurine DNA glycosylase in mitochondria leads to enhanced cell killing. Cancer Res 63: 608-615 (2003).
    • (2003) Cancer Res , vol.63 , pp. 608-615
    • Fishel, M.L.1    Seo, Y.R.2    Smith, M.L.3    Kelley, M.R.4
  • 131
    • 34548100492 scopus 로고    scopus 로고
    • Targeting human 8-oxoguanine DNA glycosylase (hOGG1) to mitochondria enhances cisplatin cytotoxicity in hepatoma cells
    • Zhang H, Mizumachi T, Carcel-Trullols J, Li L, Naito A, Spencer HJ, et al. Targeting human 8-oxoguanine DNA glycosylase (hOGG1) to mitochondria enhances cisplatin cytotoxicity in hepatoma cells. Carcinogenesis 28: 1629-1637 (2007).
    • (2007) Carcinogenesis , vol.28 , pp. 1629-1637
    • Zhang, H.1    Mizumachi, T.2    Carcel-Trullols, J.3    Li, L.4    Naito, A.5    Spencer, H.J.6
  • 132
    • 27844501168 scopus 로고    scopus 로고
    • Molecular and biological roles of Ape1 protein in mammalian base excision repair
    • Demple B and Sung J-K. Molecular and biological roles of Ape1 protein in mammalian base excision repair. DNA Repair 4: 1442-1449 (2005).
    • (2005) DNA Repair , vol.4 , pp. 1442-1449
    • Demple, B.1    Sung, J.-K.2
  • 134
    • 0036837079 scopus 로고    scopus 로고
    • H(2)O(2) induces translocation of APE/Ref-1 to mitochondria in the Raji B-cell line
    • Frossi B, Tell G, Spessotto P, Colomabtti A, Vitale G and Pucillo C. H(2)O(2) induces translocation of APE/Ref-1 to mitochondria in the Raji B-cell line. J Cell Physiol 193: 180-186 (2002).
    • (2002) J Cell Physiol , vol.193 , pp. 180-186
    • Frossi, B.1    Tell, G.2    Spessotto, P.3    Colomabtti, A.4    Vitale, G.5    Pucillo, C.6
  • 135
    • 33645928711 scopus 로고    scopus 로고
    • Identification and characterization of mitochondrial abasic (AP)- endonuclease in mammalian cells
    • Chattopadhyay R, Wiederhold L, Szczesny B, Boldogh I, Hazra TK, et al. Identification and characterization of mitochondrial abasic (AP)- endonuclease in mammalian cells. Nucleic Acids Res 34: 2060-2076 (2006).
    • (2006) Nucleic Acids Res , vol.34 , pp. 2060-2076
    • Chattopadhyay, R.1    Wiederhold, L.2    Szczesny, B.3    Boldogh, I.4    Hazra, T.K.5
  • 136
    • 0029829265 scopus 로고    scopus 로고
    • The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice
    • Xanthoudakis S, Smeyne RJ, Wallace JD and Curran T. The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice. Proc Natl Acad Sci USA 93: 8919-8923 (1996).
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8919-8923
    • Xanthoudakis, S.1    Smeyne, R.J.2    Wallace, J.D.3    Curran, T.4
  • 138
    • 0035879043 scopus 로고    scopus 로고
    • Heterozygosity for the Mouse Apex Gene Results in Phenotypes Associated with Oxidative Stress
    • Miera LB, Devaraj S, Kisby GE, Burns DK, Daniel RL, Hammer RE, et al. Heterozygosity for the Mouse Apex Gene Results in Phenotypes Associated with Oxidative Stress. Cancer Res 61: 5553-5557 (2001).
    • (2001) Cancer Res , vol.61 , pp. 5553-5557
    • Miera, L.B.1    Devaraj, S.2    Kisby, G.E.3    Burns, D.K.4    Daniel, R.L.5    Hammer, R.E.6
  • 139
    • 0030933193 scopus 로고    scopus 로고
    • Expressinon of yeast but not human apurinic/apyrimidinic endonuclease renders Chinese hamster cells more resistant to DNA damaging agents
    • Tomicici M, Eschbach E and Kaina B. Expressinon of yeast but not human apurinic/apyrimidinic endonuclease renders Chinese hamster cells more resistant to DNA damaging agents. Mutat Res 383: 155-165 (1997).
    • (1997) Mutat Res , vol.383 , pp. 155-165
    • Tomicici, M.1    Eschbach, E.2    Kaina, B.3
  • 140
    • 34250163244 scopus 로고    scopus 로고
    • Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress
    • Ho R, Rachek LI, Xu Y, Kelley MR, LeDoux SP and Wilson GL. Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress. J Neurochem 102: 13-24 (2007).
    • (2007) J Neurochem , vol.102 , pp. 13-24
    • Ho, R.1    Rachek, L.I.2    Xu, Y.3    Kelley, M.R.4    Ledoux, S.P.5    Wilson, G.L.6
  • 143
    • 33644635644 scopus 로고    scopus 로고
    • DNA polymerase 􀀁 in mitochondrial DNA replication DNA replication and repair
    • Graziewicz MA, Longley MJ and Copeland WC. DNA polymerase 􀀁 in mitochondrial DNA replication DNA replication and repair. Chem Rev 106: 383-405 (2006).
    • (2006) Chem Rev , vol.106 , pp. 383-405
    • Graziewicz, M.A.1    Longley, M.J.2    Copeland, W.C.3
  • 145
    • 22344456832 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations, oxidative stress and apoptosis in mammalian aging
    • Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, Wohlgemuth S, et al. Mitochondrial DNA mutations, oxidative stress and apoptosis in mammalian aging. Science 309: 481-484 (2005).
    • (2005) Science , vol.309 , pp. 481-484
    • Kujoth, G.C.1    Hiona, A.2    Pugh, T.D.3    Someya, S.4    Panzer, K.5    Wohlgemuth, S.6
  • 146
  • 147
    • 0034667349 scopus 로고    scopus 로고
    • Construction of transgenic mice with tissuespecific acceleration of mitochondrial DNA mutagenesis
    • Zhang D, Mott JL, Chang SW, Denniger G, Feng Z and Zassenhaus HP. Construction of transgenic mice with tissuespecific acceleration of mitochondrial DNA mutagenesis. Genomics 69: 151-161 (2000).
    • (2000) Genomics , vol.69 , pp. 151-161
    • Zhang, D.1    Mott, J.L.2    Chang, S.W.3    Denniger, G.4    Feng, Z.5    Zassenhaus, H.P.6
  • 148
    • 0037214525 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy
    • Zhang D, Mott JL, Farrar P, Ryerse JS, Chang S-W, Stevens M, et al. Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy. Cardiovasc Res 57: 147-157 (2003).
    • (2003) Cardiovasc Res , vol.57 , pp. 147-157
    • Zhang, D.1    Mott, J.L.2    Farrar, P.3    Ryerse, J.S.4    Chang, S.-W.5    Stevens, M.6
  • 149
    • 18744416025 scopus 로고    scopus 로고
    • Quantification of random genetic mutations
    • Bielas JH and Loeb LA. Quantification of random genetic mutations. Nat Methods 2: 285-290 (2005).
    • (2005) Nat Methods , vol.2 , pp. 285-290
    • Bielas, J.H.1    Loeb, L.A.2
  • 152
    • 17744393686 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human disease
    • Taylor RW and Turnbull DW. Mitochondrial DNA mutations in human disease. Nat Rev Genet 6: 389-401 (2005).
    • (2005) Nat Rev Genet , vol.6 , pp. 389-401
    • Taylor, R.W.1    Turnbull, D.W.2
  • 153
    • 0032030309 scopus 로고    scopus 로고
    • Mutations in mitochondrial DNA accumulate differentially in three different tissues during aging
    • Liu VW, Zhang C and Nagley P. Mutations in mitochondrial DNA accumulate differentially in three different tissues during aging. Nucleic Acids Res 26: 1268-1275 (1998).
    • (1998) Nucleic Acids Res , vol.26 , pp. 1268-1275
    • Liu, V.W.1    Zhang, C.2    Nagley, P.3
  • 154
    • 0028349234 scopus 로고
    • Differential accumulations of 4,977bp deletion in mitochondrial DNA of various tissues in human ageing
    • Lee HC, Pang CY, Hsu HS and Wei YH. Differential accumulations of 4,977bp deletion in mitochondrial DNA of various tissues in human ageing. Biochim Biophys Acta 1226: 37-43 (1994).
    • (1994) Biochim Biophys Acta , vol.1226 , pp. 37-43
    • Lee, H.C.1    Pang, C.Y.2    Hsu, H.S.3    Wei, Y.H.4
  • 155
    • 0035371185 scopus 로고    scopus 로고
    • Age-related mitochondrial genotypic and phenotypic alterations in human skeletal muscle
    • Pesce V, Cormio A, Fracasso F, Vecchiet J, Felzani G, Lezza AM, et al. Age-related mitochondrial genotypic and phenotypic alterations in human skeletal muscle. Free Radic Biol Med 30: 1223-1233 (2001).
    • (2001) Free Radic Biol Med , vol.30 , pp. 1223-1233
    • Pesce, V.1    Cormio, A.2    Fracasso, F.3    Vecchiet, J.4    Felzani, G.5    Lezza, A.M.6
  • 156
    • 29144486726 scopus 로고    scopus 로고
    • Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice
    • Tyynismaa H, Mjosund KP, Wanrooij S, Lappalainen I, Ylikallio E, Jalank A, et al. Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice. Proc Natl Acad Sci USA 102: 17687-17692 (2005).
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 17687-17692
    • Tyynismaa, H.1    Mjosund, K.P.2    Wanrooij, S.3    Lappalainen, I.4    Ylikallio, E.5    Jalank, A.6
  • 159
    • 33646375711 scopus 로고    scopus 로고
    • High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
    • Bender A, Krishnan KJ, Morris CM, Taylor GA, Reeve AK, Perry RH, et al. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat Genet 38: 515-517 (2006).
    • (2006) Nat Genet , vol.38 , pp. 515-517
    • Bender, A.1    Krishnan, K.J.2    Morris, C.M.3    Taylor, G.A.4    Reeve, A.K.5    Perry, R.H.6
  • 160
    • 33646351299 scopus 로고    scopus 로고
    • Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
    • Kraytsberg Y, Kudryavtseva E, McKee AC, Geula C, Kowall NW and Khrapko K. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat Genet 38: 518-520 (2006).
    • (2006) Nat Genet , vol.38 , pp. 518-520
    • Kraytsberg, Y.1    Kudryavtseva, E.2    McKee, A.C.3    Geula, C.4    Kowall, N.W.5    Khrapko, K.6
  • 162
    • 0028140454 scopus 로고
    • Distribution of wild-type and common deletion forms of mtDNA in normal and respiration-deficient muscle fibers from patients with mitochondrial myopathy
    • Sciacco M, Bonilla E, Schon EA, DiMauro S and Moraes CT. Distribution of wild-type and common deletion forms of mtDNA in normal and respiration-deficient muscle fibers from patients with mitochondrial myopathy. Hum Mol Genet 3:13-19 (1994).
    • (1994) Hum Mol Genet , vol.3 , pp. 13-19
    • Sciacco, M.1    Bonilla, E.2    Schon, E.A.3    Dimauro, S.4    Moraes, C.T.5
  • 165
    • 10744219959 scopus 로고    scopus 로고
    • Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure
    • Chimenti C, Kajstura J, Torella D, Urbanek K, Heleniak H, Colussi C, et al. Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure. Circ Res 93: 604-613 (2003).
    • (2003) Circ Res , vol.93 , pp. 604-613
    • Chimenti, C.1    Kajstura, J.2    Torella, D.3    Urbanek, K.4    Heleniak, H.5    Colussi, C.6
  • 167
  • 168
    • 38349114089 scopus 로고    scopus 로고
    • Denervation and the aging of skeletal muscle
    • Carlson BM. Denervation and the aging of skeletal muscle. Basic Appl Myol 14: 135-139 (2004).
    • (2004) Basic Appl Myol , vol.14 , pp. 135-139
    • Carlson, B.M.1
  • 169
    • 0024262833 scopus 로고
    • Effects of age on the number and histochemical properties of muscle fibers and motoneurons in the rat extensor digitorum longus muscle
    • Ishihara A and Araki H. Effects of age on the number and histochemical properties of muscle fibers and motoneurons in the rat extensor digitorum longus muscle. Mech Ageing Dev 45: 213-221 (1988).
    • (1988) Mech Ageing Dev , vol.45 , pp. 213-221
    • Ishihara, A.1    Araki, H.2
  • 170
    • 0033396991 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases
    • Mattson MP, Pedersen WA, Duan W, Culmsee C and Camandola S. Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases. Ann NY Acad Sci 893: 154-175 (1999).
    • (1999) Ann NY Acad Sci , vol.893 , pp. 154-175
    • Mattson, M.P.1    Pedersen, W.A.2    Duan, W.3    Culmsee, C.4    Camandola, S.5
  • 171
    • 22144499238 scopus 로고    scopus 로고
    • Caloric restriction reduces cell loss and maintains estrogen receptor-alpha immunoreactivity in the pre-optic hypothalamus of female B6D2F1 mice
    • Yaghmaie F, Saeed O, Garan SA, Freitag W, Timiras PS and Sternberg H. Caloric restriction reduces cell loss and maintains estrogen receptor-alpha immunoreactivity in the pre-optic hypothalamus of female B6D2F1 mice. Neuro Endocrinol Lett 26: 197-203 (2005).
    • (2005) Neuro Endocrinol Lett , vol.26 , pp. 197-203
    • Yaghmaie, F.1    Saeed, O.2    Garan, S.A.3    Freitag, W.4    Timiras, P.S.5    Sternberg, H.6
  • 172
    • 0034603991 scopus 로고    scopus 로고
    • Caloric restriction prevents oxidative damage induced by the carcinogen clofibrate in mouse liver
    • Qu B, Halliwell B, Ong CN, Lee BL and Li Q-T. Caloric restriction prevents oxidative damage induced by the carcinogen clofibrate in mouse liver. FEBS Lett 473: 85-88 (2000).
    • (2000) FEBS Lett , vol.473 , pp. 85-88
    • Qu, B.1    Halliwell, B.2    Ong, C.N.3    Lee, B.L.4    Li, Q.-T.5
  • 173
    • 0031844017 scopus 로고    scopus 로고
    • Response of lens epithelial cells to hydrogen peroxide stress and the protective effect of caloric restriction
    • Li Y, Yan Q, Pendergrass WR and Wolf NS. Response of lens epithelial cells to hydrogen peroxide stress and the protective effect of caloric restriction. Exp Cell Res 239: 254-63 (1998).
    • (1998) Exp Cell Res , vol.239 , pp. 254-263
    • Li, Y.1    Yan, Q.2    Pendergrass, W.R.3    Wolf, N.S.4
  • 174
    • 0030793931 scopus 로고    scopus 로고
    • Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon
    • Herrero A and Barja G. Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon. Mech Ageing Dev 98: 95-111 (1997).
    • (1997) Mech Ageing Dev , vol.98 , pp. 95-111
    • Herrero, A.1    Barja, G.2
  • 175
    • 0032525349 scopus 로고    scopus 로고
    • H2O2 production of heart mitochondria and aging rate are slower in canaries and parakeets than in mice: Sites of free radical generation and mechanisms involved
    • Herrero A and Barja G. H2O2 production of heart mitochondria and aging rate are slower in canaries and parakeets than in mice: sites of free radical generation and mechanisms involved. Mech Ageing Dev 103: 133-146 (1998).
    • (1998) Mech Ageing Dev , vol.103 , pp. 133-146
    • Herrero, A.1    Barja, G.2
  • 176
    • 0034751958 scopus 로고    scopus 로고
    • Effect of short-term caloric restriction on H2O2 production and oxidative DNA damage in rat liver mitochondria and location of the free radical source
    • Gredilla R, Barja G and Lopez-Torres M. Effect of short-term caloric restriction on H2O2 production and oxidative DNA damage in rat liver mitochondria and location of the free radical source. J Bioenerg Biomembr 33: 279-287 (2001).
    • (2001) J Bioenerg Biomembr , vol.33 , pp. 279-287
    • Gredilla, R.1    Barja, G.2    Lopez-Torres, M.3
  • 177
    • 33845635647 scopus 로고    scopus 로고
    • Carbohydrate restriction does not change mitochondrial free radical generation and oxidative DNA damage
    • Sanz A, Gomez J, Caro P and Barja G. Carbohydrate restriction does not change mitochondrial free radical generation and oxidative DNA damage. J Bioenerg Biomembr 38: 327-333 (2006).
    • (2006) J Bioenerg Biomembr , vol.38 , pp. 327-333
    • Sanz, A.1    Gomez, J.2    Caro, P.3    Barja, G.4
  • 178
    • 33745970444 scopus 로고    scopus 로고
    • Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins
    • Sanz A, Caro P, Ayala V, Portero-Otin M, Pamplona R and Barja G. Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins. FASEB J 20: 1064-1073 (2006).
    • (2006) FASEB J , vol.20 , pp. 1064-1073
    • Sanz, A.1    Caro, P.2    Ayala, V.3    Portero-Otin, M.4    Pamplona, R.5    Barja, G.6
  • 179
    • 0942276492 scopus 로고    scopus 로고
    • Short-term CR decreases cardiac mitochondrial oxidant production but increases carbonyl content
    • Judge S, Judge A, Grune T and Leeuwenburgh C. Short-term CR decreases cardiac mitochondrial oxidant production but increases carbonyl content. Am J Physiol Regul Integr Comp Physiol 286: R254-R259 (2004).
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Judge, S.1    Judge, A.2    Grune, T.3    Leeuwenburgh, C.4
  • 180
    • 34548418947 scopus 로고    scopus 로고
    • Effect of 8.5% and 25% caloric restriction on mitochondrial free radical production and oxidative stress in rat liver
    • Gomez J, Caro P, Naudi A, Portero-Otin M, Pamplona R and Barja G. Effect of 8.5% and 25% caloric restriction on mitochondrial free radical production and oxidative stress in rat liver. Biogerontology 8: 555-566 (2007).
    • (2007) Biogerontology , vol.8 , pp. 555-566
    • Gomez, J.1    Caro, P.2    Naudi, A.3    Portero-Otin, M.4    Pamplona, R.5    Barja, G.6
  • 181
    • 36249022195 scopus 로고    scopus 로고
    • Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity
    • Csiszar A, Labinskyy N, Zhao X, Hu F, Serpillon S, Huang Z, et al. Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity. Aging Cell 6: 783-97 (2007).
    • (2007) Aging Cell , vol.6 , pp. 783-797
    • Csiszar, A.1    Labinskyy, N.2    Zhao, X.3    Hu, F.4    Serpillon, S.5    Huang, Z.6
  • 182
    • 0027442218 scopus 로고
    • Biochemical correlates of longevity in two closely related rodent species
    • Sohal RS, Ku H-H and Agarwal S. Biochemical correlates of longevity in two closely related rodent species. Biochem Biophys Res Commun 196: 7-11 (1993).
    • (1993) Biochem Biophys Res Commun , vol.196 , pp. 7-11
    • Sohal, R.S.1    Ku, H.-H.2    Agarwal, S.3
  • 183
    • 0029147191 scopus 로고
    • Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies
    • Sohal RS, Sohal BH and Orr WC. Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies. Free Radic Biol Med 19: 499-504 (1995).
    • (1995) Free Radic Biol Med , vol.19 , pp. 499-504
    • Sohal, R.S.1    Sohal, B.H.2    Orr, W.C.3
  • 184
    • 43249123912 scopus 로고    scopus 로고
    • Forty percent and eighty percent methionine restriction decrease mitochondrial ROS generation and oxidative stress in rat liver
    • Caro P, Gomez J, Lopez-Torres M, Sanchez I, Naudí A, Jove M, et al. Forty percent and eighty percent methionine restriction decrease mitochondrial ROS generation and oxidative stress in rat liver. Biogerontology 9: 183-196 (2008).
    • (2008) Biogerontology , vol.9 , pp. 183-196
    • Caro, P.1    Gomez, J.2    Lopez-Torres, M.3    Sanchez, I.4    Naudí, A.5    Jove, M.6
  • 185
    • 17144402990 scopus 로고    scopus 로고
    • Lack of effect of caloric restriction on bioenergetics and reactive oxygen species production in intact rat heptocytes
    • Lambert AJ and Merry BJ. Lack of effect of caloric restriction on bioenergetics and reactive oxygen species production in intact rat heptocytes. J Gerontol A Biol Sci Med Sci 60: 175-180 (2005).
    • (2005) J Gerontol a Biol Sci Med Sci , vol.60 , pp. 175-180
    • Lambert, A.J.1    Merry, B.J.2


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