FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies

Molecular and Cellular Biology

Volumn 19, Issue 1, 1999, Pages 216-228

  Sun, Jingtao ^a   Tower, John ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; RECOMBINASE;

ALLELE; ARTICLE; CATALYSIS; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; ENZYME INDUCTION; EPISTASIS; GENE EXPRESSION; GENE LOCATION; GENETIC ANALYSIS; LIFESPAN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENE;

DROSOPHILA MELANOGASTER;

EID: 0032908347     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.1.216     Document Type: Article

References (62)

1. Ames, B. N., M. K. Shigenaga, and T. M. Hagen. 1993. Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA 90:7915-7922.
2. Ashburner, M. 1989. Drosophila: a laboratory handbook. Cold Spring Harbor Laboratory Press. Plainview, N.Y.
3. Avraham, K. B., M. Schickler, D. Sapoznikor, R. Yarom, and Y. Groner. 1988. Down's syndrome: abnormal neuromuscular junction in tongue of transgenic mice with elevated levels of human Cu/Zn-superoxide dismutase. Cell 54:823-829.
4. Baker, G. T., M. Jacobsen, and G. Mokrynski. 1989. Aging in Drosophila, p. 511-578. In V. Crisotfalo (ed.). Cell biology handbook in aging. CRC Press, Inc., Boca Raton, Fla.
5. Bar-Peled, O., E. Korkotian, M. Segal, and Y. Groner. 1996. Constitutive overexpression of Cu/Zn superoxide dismutase exacerbates kainic acid-induced apoptosis of transgenic Cu/Zn superoxide dismutase neurons. Proc. Natl. Acad. Sci. USA 93:8530-8535.
6. Basler, K., and G. Struhl. 1994. Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature 368:208-214.
7. Bieschke, E. T., J. C. Wheeler, and J. Tower. 1998. Doxycycline-induced transgene expression during Drosophila development and aging. Mol. Gen. Genet. 258:571-579.
8. Brand, A. H., and E. L. Dormand. 1995. The GAL4 system as a tool for unravelling the mysteries of the Drosophila nervous system. Curr. Opin. Neurobiol. 5:572-578,
9. Brand, A. H., and N. Perrimon. 1993. Targeted gene expression as a means of alterine cell fates and generating dominant phenotypes. Development 118:401-415.
10. Brown, R. H. 1995. Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice. Cell 80:687-692.
11. Buck, S., R. A. Wells, S. P. Dudas, G. T. Baker, and R. Arking. 1993. Chromosomal localization and regulation of the longevity determinant genes in a selected strain of Drosophila metanogaster. Heredity 71:11-22.
12. Curtsinger, J. W. 1997. Mortal 1.0. computer software for survival data analysis, http://oldfly.cbs.umn.edu.
13. Curtsinger, J. W., H. H. Fukui, A. A. Khazaeli, A. Kirscher, S. D. Pletcher, D. E. L. Promislow, and M. Tatar. 1995. Genetic variation in aging. Annu. Rev. Genet. 29:553-575.
14. Deckert-Cruz, D. J., R. H. Tyler, J. E. Landmesser, and M. R. Rose. 1997. Allozyme differentiation in response to laboratory demographic selection of Drosophila melanogasler. Evolution 51:865-872.
15. Deng, H.-X., A. Hentati, J. A. Tainer, Z. Iqbal, A. Cayabyab, W.-Y. Hung, E. D. Getzoff, P. Hu, B. Gerzfeldt, R. P. Roos, C. Warner, G. Deng, E. Soriano, C. South, H. E. Parge, A. Ahmed, A. D. Roses, R. A. Hallewell, M. A. Pericak-Vance, and T. Siddique. 1993. Amyotrophic lateral sclerosis and structural defects in Cu,Zn Superoxide dismutase. Science 261:1047-1051.
16. Dudas, S. P., and R. Arking. 1995. A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a long-lived strain of Drosophila. J. Gerontol. Biol. Sci. 50A:B117-B127.
17. Dymecki, S. M. 1996. Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice. Proc. Natl. Acad. Sci. USA 93:6191-6196.
18. Golic, K. G., and S. Lindquist. 1989. The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome. Cell 59:499-509.
19. Gossen, M., S. Freundlieb, G. Bender, G. Muller, W. Hillen, and H. Bujard. 1995. Transcriptional activation by tetracyclines in mammalian cells. Science 268:1769-1776.
20. Griswold, C. M., A. L. Matthews, K. E. Bewley, and J. W. Mahaffey. 1993. Molecular characterization of rescue of acatalesemic mutants of Drosophila melanogtister. Genetics 134:731-788.
21. Kaiser, M., M. Gasser, R. Ackermann, and S. C. Stearns. 1997. P element inserts in transgenic flies: a cautionary tale. Heredity 78:1-11.
22. Khazaeli, A. A., M. Tatar, S. D. Pletcher, and J. W. Curtsinger. 1997. Heat-induced longevity extension in Drosophila. I. Heat treatment, mortality, and thermotolerance. J. Gerontol. Biol. Sci. 52A:B48-B52.
23. Kistner, A., M. Gossen, F. Zimmermann, J. Jerecic, C. Ullmer, H. Lubbert, and H. Bujard. 1996. Doxycycline-mcdiated quantitative and tissue-specific control of gene expression in transgenic mice. Proc. Natl. Acad. Sci. USA 93:10933-10938.
24. Kostyuk, V. A., and A. I. Potapovich. 1989. Superoxide-driven oxidation of quercetin and a simple sensitive assay for determination of superoxide dismutase. Biochem. Int. 19:1117-1124.
25. Lee, E. T. 1992. Statistical methods for survival data analysis. John Wiley & Sons, Inc., New York, N.Y.
26. Leffelaar, D., and T. Grigliatti. 1984. Age-dependent behavior loss in adult Drosophila melanogaster. Dev. Genet. 4:211-220.
27. Lindsley, D. L., and G. G. Zimm. 1992. The genome of Drosophila melanogaster. Academic Press. Inc., San Diego, Calif.
28. Luck, H. 1965. Catalase assay, p. 885-894. In H. Bergmeyer (ed.), Methods of enzymatic analysis. Academic Press. Inc., New York, N.Y.
29. Luckinbill, L. S., R. Arking, M. Clare, W. Cirocco, and S. Buck. 1984. Selection for delayed senescence in Drosophila melanogaster. Evolution 38: 996-1003.
30. Mackay, W. J., and G. C. Bewley. 1989. The genetics of catalase in Drosophila melanogaster. Isolation and characterization of acatalasemic mutants. Genetics 122:643-652.
31. Miller, R. G. 1981. Survival analysis. John Wiley & Sons, Inc., New York, N.Y.
32. Miquel, J., P. R. Lundgren, and R. Binnard. 1972. Negative geotaxis and mating behavior in control and gamma-irradiated Drosophila. Drosophila Inform. Serv. 48:48-62.
33. Orr, E. C., G. C. Bewley, and W. C. Orr. 1990. cDNA and deduced amino acid sequence of Drosophila catalase. Nucleic Acids Res. 18:3663.
34. Orr, W., and R. S. Sohal. 1994. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263: 1128-1130.
35. Orr, W. C., and R. J. Sohal. 1993. Effects of Cu-Zn Superoxide dismutase overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster. Arch. Biochem. Biophys. 301:34-40.
36. Orr, W. C., and R. S. Sohal. 1992. The effects of catalase gene overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster. Arch. Biochem. Biophys. 297:35-41.
37. Parkes, T. L., A. J. Elia, D. Dickson, A. J. Hilliker, J. P. Phillips, and G. L. Boulianne. 1998. Extension of Drosophila lifespan by overexpression of human SODI in motorneurons. Nat. Genet. 19:171-174.
38. Partridge, L., and N. H. Barton. 1993. Optimality, mutation and the evolution of aging. Nature 362:305-311.
39. Partridge, L., and K. Fowler. 1992 Direct and correlated responses to selection on age at reproduction in Drosophila melanogaster. Evolution 46: 76-91.
40. Phillips, J. P., S. D. Campbell, D. Michaud, M. Charbonneau, and A. J. Hilliker. 1989. Null mutation of copper/zinc Superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity. Proc. Nail. Acad. Sci. USA 86:2761-2765.
41. Reveillaud, I., A. Niedzwiecki, K. G. Bensch, and J. E. Fleming. 1991. Expression of bovine superoxide dismutase in Drosophila melanogaster augments resistance to oxidative stress. Mol. Cell. Biol. 11:632-640.
42. Rose, M. R. 1984. Laboratory evolution of postponed senescence in Drosophila melanogaster. Evolution 38:1004-1010.
43. Rosen, D. R., T. Siddique, D. Patterson, D. A. Figlewicz, P. Sapp, A. Hentati, D. Donaldson, J. Goto, J. P. O'Reagan, H.-X. Deng, Z. Rahmani, A. Krizus, D. McKenna-Yasek, A. Cayabyab, S. M. Gaston, R. Berger, R. E. Tanzi, J. J. Halperin, B. Herzfeldt, R. Van den Bergh, W.-Y. Hung, T. Bird, G. Deng, D. W. Mulder, C. Smyth, N. G. Liang, E. Soriano, M. A. Pericak-Vance, J. Haines, G. A. Rouleau, J. S. Gusella, H. R. Horvitz, and R. H. Brown, Jr. 1993. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362:59-62.
44. Rubin, G. M., and A, C. Spradling. 1982. Genetic transformation of Drosophila with transposable element vectors. Science 218:348-353.
45. Seto, N. O. L., S. Hayashi, and G. M. Tener. 1990. Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life span. Proc. Natl. Acad. Sci. USA 87:4270-4274.
46. Simon, J. A., and J. T. Lis. 1987. A germline transformation analysis reveals flexibility in the organization of heat shock consensus elements. Nucleic Acids Res. 15:2971-2988.
47. Simon, J. A., C. A. Sutton, R. B. Lobeil, R. L. Glaser, and J. T. Lis. 1985. Determinants of heat shock-induced chromosome puffing. Cell 40:805-817.
48. Sokal, R. R., and F. J. Rohlf. 1981. Biometry, 2nd ed. W. H. Freeman & Co., New York, N.Y.
49. Stadtman, E. R. 1992. Protein oxidation and aging. Science 257:1220-1224.
50. Slavery, B. E., J. P. Phillips, and A. J. Hilliker. 1990. Phenotypic consequences of copper/zinc superoxide dismutase overexpression in Drosophila melanogaster. Genome 33:867-872.
51. Stearns, S. C., and M. Kaiser. 1993. The effects of enhanced expression of elongation factor EF1-α on lifespan in Drosophila melanogaster. Genetica 91:167-182.
52. Stearns, S. C., M. Kaiser, and E. Hillesheim. 1993. Effects on fitness components of enhanced expression of elongation factor EF-1α in Drosophila melanogaster. I. The contrasting approaches of molecular and population biologists. Am. Nat. 142:961-993.
53. Strong, R., M. B. Mattamal, and A. C. Andorn. 1993. Free radicals, the aging brain, and age-related neurodegenerative disorders, p. 223-246. In B. P. Yu (ed.), Free radicals in aging. CRC Press. Inc., Boca Raton, Fla.
54. Struhl, G., and K. Basler. 1993. Organizing activity of wingless protein in Drosophila. Cell 72:527-540.
55. Tatar, M. Transgenes in the analysis of lifespan and fitness. Am. Nat., in press.
56. Tatar, M., A. A. Khazaeli, and J. W. Curtsinger. 1997. Chaperoning extended life. Nature 390:30.
57. Thummel, C. S., and V. Pirotta. 1992. New pCaSpeR P element vectors. Drosophila Inform. Serv. 71:150.
58. Tower, J. 1996. Aging mechanisms in fruit flies. Bioessays 18:799-807.
59. Trout, W. E., and W. D. Kaplan. 1970. A relation between longevity, metabolic rate, and activity in Shaker mutants of Drosophila melanogaster. Exp. Gerontol. 5:83-92.
60. Tyler, R. H., H. Brar, M. Singh, A. Latorre, J. L. Graves, L. D. Mueller, M. R. Rose, and F. J. Avala. 1993. The effect of superoxide dismutase alleles on aging in Drosophila. Genetica 91:143-150.
61. Wheeler, J. C., E. T. Bieschke, and J. Tower. 1995. Muscle-specific expression of Drosophila hsp70 in response to aging and oxidative stress. Proc. Natl. Acad. Sci. USA 92:10408-10412.
62. Yu, B. P. 1993. Oxidative damage by free radicals and lipid peroxidation in aging, p. 57-88. In B. P. Yu (ed.), Free radicals in aging. CRC Press. Inc., Boca Raton, Fla.