Imbalancing the DNA base excision repair pathway in the mitochondria; Targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing

Cancer Research

Volumn 63, Issue 3, 2003, Pages 608-615

  Fishel, Melissa L ^a   Seo, Young R ^a   Smith, Martin L ^a   Kelley, Mark R ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,N6 ETHENOADENINE; 3 METHYLADENINE; ADENINE DERIVATIVE; CELL NUCLEUS DNA; DNA BASE; DNA GLYCOSYLTRANSFERASE; MANGANESE SUPEROXIDE DISMUTASE; MESYLIC ACID METHYL ESTER; MITOCHONDRIAL DNA; N METHYLPURINE DNA GLYCOSYLTRANSFERASE; UNCLASSIFIED DRUG;

ALKYLATION; APOPTOSIS; APURINIC SITE; ARTICLE; BREAST CANCER; CANCER CHEMOTHERAPY; CELL KILLING; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; EXCISION REPAIR; GENE INSERTION; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; MITOCHONDRION; MUTAGENICITY; PRIORITY JOURNAL;

ANNEXIN A5; ANTINEOPLASTIC AGENTS, ALKYLATING; APOPTOSIS; BREAST NEOPLASMS; CASPASE 3; CASPASES; CELL SURVIVAL; DNA GLYCOSYLASES; DNA REPAIR; DNA, MITOCHONDRIAL; FLUORESCEIN-5-ISOTHIOCYANATE; GENE THERAPY; HUMANS; METHYL METHANESULFONATE; MICROSCOPY, CONFOCAL; MITOCHONDRIA; N-GLYCOSYL HYDROLASES; STAINING AND LABELING; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY;

EID: 0037309710     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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