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Volumn 163, Issue 1, 2003, Pages 171-180

Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity

Author keywords

[No Author keywords available]

Indexed keywords

ADULTHOOD; ALLELE; ARTICLE; CAENORHABDITIS ELEGANS; COOLING; GENE MUTATION; GENETIC SELECTION; HEAT TOLERANCE; LARVA; LARVAL STAGE; LIFESPAN; LONGEVITY; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROGENY; SEXUAL MATURITY; STARVATION; STRESS; SURVIVAL;

EID: 0037274713     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (136)

References (65)
  • 1
    • 0026475394 scopus 로고
    • The Caenorhabditis elegans unc-13 gene product is a phospholipid-dependent high-affinity phorbol ester receptor
    • AHMED, S., I. N. MARUYAMA, R. KOZMA, J. LEE, S. BRENNER et al., 1992 The Caenorhabditis elegans unc-13 gene product is a phospholipid-dependent high-affinity phorbol ester receptor. Biochem. J. 287: 995-999.
    • (1992) Biochem. J. , vol.287 , pp. 995-999
    • Ahmed, S.1    Maruyama, I.N.2    Kozma, R.3    Lee, J.4    Brenner, S.5
  • 4
    • 0034659485 scopus 로고    scopus 로고
    • daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans
    • ANTEBI, A., W. H. YEH, D. TAIT, E. M. HEDGECOCK and D. L. RIDDLE, 2000 daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans. Genes Dev. 14: 1512-1527.
    • (2000) Genes Dev. , vol.14 , pp. 1512-1527
    • Antebi, A.1    Yeh, W.H.2    Tait, D.3    Hedgecock, E.M.4    Riddle, D.L.5
  • 5
    • 0033576579 scopus 로고    scopus 로고
    • Regulation of lifespan by sensory perception in Caenorhabditis elegans
    • APFELD, J. and C. KENYON, 1999 Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature 402: 804-809.
    • (1999) Nature , vol.402 , pp. 804-809
    • Apfeld, J.1    Kenyon, C.2
  • 6
    • 0027196132 scopus 로고
    • The Caenorhabditis elegans unc-31 gene affects multiple nervous system-controlled functions
    • AWERY, L., C. I. BARGMANN and H. R. HORVITZ, 1993 The Caenorhabditis elegans unc-31 gene affects multiple nervous system-controlled functions. Genetics 134: 455-464.
    • (1993) Genetics , vol.134 , pp. 455-464
    • Awery, L.1    Bargmann, C.I.2    Horvitz, H.R.3
  • 7
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • BRENNER, S., 1974 The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 9
    • 0016766716 scopus 로고
    • The dauer larva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans
    • CASSADA, R. C., and R. L. RUSSELL, 1975 The dauer larva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans. Dev. Biol. 46: 326-342.
    • (1975) Dev. Biol. , vol.46 , pp. 326-342
    • Cassada, R.C.1    Russell, R.L.2
  • 10
    • 0029984472 scopus 로고    scopus 로고
    • Direct isolation of longevity mutants in the nematode Caenorhabditis elegans
    • DUHON, S. A., S. MURAKAMI and T. E. JOHNSON, 1996 Direct isolation of longevity mutants in the nematode Caenorhabditis elegans. Dev. Genet. 18: 144-153.
    • (1996) Dev. Genet. , vol.18 , pp. 144-153
    • Duhon, S.A.1    Murakami, S.2    Johnson, T.E.3
  • 11
    • 0035853552 scopus 로고    scopus 로고
    • Regulation of longevity and stress resistance by Sch9 in yeast
    • FABRIZIO, P., F. POZZA, S. D. PLETCHER, C. M. GENDRON and V. D. LONGO, 2001 Regulation of longevity and stress resistance by Sch9 in yeast. Science 292: 288-290.
    • (2001) Science , vol.292 , pp. 288-290
    • Fabrizio, P.1    Pozza, F.2    Pletcher, S.D.3    Gendron, C.M.4    Longo, V.D.5
  • 12
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • FINKEI, T., and N. J. HOLBROOK, 2000 Oxidants, oxidative stress and the biology of ageing. Nature 408: 239-247.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkei, T.1    Holbrook, N.J.2
  • 13
    • 0035811073 scopus 로고    scopus 로고
    • Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
    • FLURKEY, K., J. PAPACONSTANTINOU, R. A. MILLER and D. E. HARRISON, 2001 Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc. Natl. Acad. Sci. USA 98: 6736-6741.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6736-6741
    • Flurkey, K.1    Papaconstantinou, J.2    Miller, R.A.3    Harrison, D.E.4
  • 14
    • 0023831256 scopus 로고
    • A mutation in the age-1 gene in C. elegans lengthens life and reduces hermaphrodite fertility
    • FRIEDMAN, D. B., and T. E. JOHNSON, 1988 A mutation in the age-1 gene in C. elegans lengthens life and reduces hermaphrodite fertility. Genetics 118: 75-86.
    • (1988) Genetics , vol.118 , pp. 75-86
    • Friedman, D.B.1    Johnson, T.E.2
  • 15
    • 0031685525 scopus 로고    scopus 로고
    • Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans
    • GEMS, D., A. J. SUTTON, M. L. SUNDERMEYER, P. S. ALBERT, K. V. KING et al., 1998 Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 150: 129-155.
    • (1998) Genetics , vol.150 , pp. 129-155
    • Gems, D.1    Sutton, A.J.2    Sundermeyer, M.L.3    Albert, P.S.4    King, K.V.5
  • 16
    • 0035656274 scopus 로고    scopus 로고
    • A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span
    • GERISCH, B., C. WEITZEL, C. KOBER-EISERMANN, V. ROTTIERS and A. ANTEBI, 2001 A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span. Dev. Cell. 1: 841-851.
    • (2001) Dev. Cell. , vol.1 , pp. 841-851
    • Gerisch, B.1    Weitzel, C.2    Kober-Eisermann, C.3    Rottiers, V.4    Antebi, A.5
  • 17
    • 0034626747 scopus 로고    scopus 로고
    • Genetic pathways that regulate ageing in model organisms
    • GUARENTE, L., and C. KENYON, 2000 Genetic pathways that regulate ageing in model organisms, Nature 408: 255-262.
    • (2000) Nature , vol.408 , pp. 255-262
    • Guarente, L.1    Kenyon, C.2
  • 18
    • 0022358866 scopus 로고
    • Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes
    • HEDGECOCK, E. M., J. G. CULOTTI, N. THOMSON and L. A. PERKINS, 1985 Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes. Dev. Biol. 111: 158-170.
    • (1985) Dev. Biol. , vol.111 , pp. 158-170
    • Hedgecock, E.M.1    Culotti, J.G.2    Thomson, N.3    Perkins, L.A.4
  • 19
    • 0032782364 scopus 로고    scopus 로고
    • The daf-2gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
    • HONDA, Y.,and S. HONDA, 1999 The daf-2gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J. 13: 1385-1393.
    • (1999) FASEB J. , vol.13 , pp. 1385-1393
    • Honda, Y.1    Honda, S.2
  • 20
    • 0036333147 scopus 로고    scopus 로고
    • DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity
    • JIA, K., P. S. ALBERT and D. L. RIDDLE, 2002 DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity. Development 129: 221-231.
    • (2002) Development , vol.129 , pp. 221-231
    • Jia, K.1    Albert, P.S.2    Riddle, D.L.3
  • 21
    • 0033784405 scopus 로고    scopus 로고
    • Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors
    • JOHNSON, T. E., J. CYPSER, E. DE CASTRO, S. DE CASTRO, S. HENDERSON et al., 2000 Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors. Exp. Gerontol. 35: 687-694.
    • (2000) Exp. Gerontol. , vol.35 , pp. 687-694
    • Johnson, T.E.1    Cypser, J.2    De Castro, E.3    De Castro, S.4    Henderson, S.5
  • 22
    • 0034892172 scopus 로고    scopus 로고
    • Changes in gene expression associated with developmental arrest and longevity in Caenorhabditis elegans
    • JONES, S. J., D. L. RIDDLE. A. T. POUZYREV, V. E. VELCULESCU, L. HILLIER et al. 2001 Changes in gene expression associated with developmental arrest and longevity in Caenorhabditis elegans. Genome Res. 11: 1346-1352.
    • (2001) Genome Res. , vol.11 , pp. 1346-1352
    • Jones, S.J.1    Riddle, D.L.2    Pouzyrev, A.T.3    Velculescu, V.E.4    Hillier, L.5
  • 23
    • 0035917440 scopus 로고    scopus 로고
    • A conserved regulatory system for aging
    • KENYON, C., 2001 A conserved regulatory system for aging. Cell 105: 165-168.
    • (2001) Cell , vol.105 , pp. 165-168
    • Kenyon, C.1
  • 24
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • KENYON, C., J. CHANG, E. GENSCH, A. RUDNER and R. TABTIANG, 1993 A C. elegans mutant that lives twice as long as wild type. Nature 366: 461-464.
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 25
    • 0030813398 scopus 로고    scopus 로고
    • daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • KIMURA, K. D., H. A. TISSENBAUM, Y. LIU and G. RUVKUN, 1997 daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942-946.
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 26
    • 0017763799 scopus 로고
    • Aging in the nematode Caenorhabditis elegans: Major biological and environmental factors influencing life span
    • KLASS, M, R., 1977 Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span, Mech. Ageing Dev. 6: 413-429.
    • (1977) Mech. Ageing Dev. , vol.6 , pp. 413-429
    • Klass, M.R.1
  • 27
    • 0021056471 scopus 로고
    • A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results
    • KLASS, M. R., 1983 A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results. Mech. Ageing Dev. 22: 279-286.
    • (1983) Mech. Ageing Dev. , vol.22 , pp. 279-286
    • Klass, M.R.1
  • 28
    • 0032573178 scopus 로고    scopus 로고
    • The genetics of caloric restriction in Caenorhabditis elegans
    • LAKOWSKI, B., and S. HEKIMI, 1998 The genetics of caloric restriction in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 95: 13091-13096.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13091-13096
    • Lakowski, B.1    Hekimi, S.2
  • 29
    • 0027515616 scopus 로고
    • Aging and resistance to oxidative damage in Caenohabditis elegans
    • LARSEN, P. L., 1993 Aging and resistance to oxidative damage in Caenohabditis elegans. Proc. Natl. Acad. Sci. USA 90: 8905-8909.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8905-8909
    • Larsen, P.L.1
  • 30
    • 0028930267 scopus 로고
    • Genes that regulate both development and longevity in Caenorhabditis elegans
    • LARSEN, P. L., P. S. ALBERT and D. L. RIDDLE, 1995 Genes that regulate both development and longevity in Caenorhabditis elegans. Genetics 139: 1567-1583.
    • (1995) Genetics , vol.139 , pp. 1567-1583
    • Larsen, P.L.1    Albert, P.S.2    Riddle, D.L.3
  • 32
    • 0030657540 scopus 로고    scopus 로고
    • daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
    • LIN, K., J. B. DORMAN, A. RODAN and C. KENYON, 1997 daf-16: an HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278: 1319-1322.
    • (1997) Science , vol.278 , pp. 1319-1322
    • Lin, K.1    Dorman, J.B.2    Rodan, A.3    Kenyon, C.4
  • 33
    • 0032582489 scopus 로고    scopus 로고
    • Extended life-span and stress resistance in the Drosophila mutant methuselah
    • LIN, Y. J., L. SEROUDE and S. BENZER, 1998 Extended life-span and stress resistance in the Drosophila mutant methuselah. Science 282: 943-946.
    • (1998) Science , vol.282 , pp. 943-946
    • Lin, Y.J.1    Seroude, L.2    Benzer, S.3
  • 34
    • 0036175825 scopus 로고    scopus 로고
    • Stress resistance as a determinate of C. elegans lifespan
    • LITHGOW, A., G. J., and G. A. WALKER, 2002 Stress resistance as a determinate of C. elegans lifespan. Mech. Ageing Dev. 123: 765-771.
    • (2002) Mech. Ageing Dev. , vol.123 , pp. 765-771
    • Lithgow, A.1    Walker, G.A.2
  • 35
    • 0029123058 scopus 로고
    • Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress
    • LITHGOW, G. J., T. M. WHITE, S. MELOV and T. E. JOHNSON, 1995 Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc. Natl. Acad. Sci. USA 92: 7540-7544.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7540-7544
    • Lithgow, G.J.1    White, T.M.2    Melov, S.3    Johnson, T.E.4
  • 36
    • 0030007767 scopus 로고    scopus 로고
    • Genetic analysis of the roles of daf-28 and age-1 in regulating Caenorhabditis elegans dauer formation
    • MALONE, E. A., T. INOUE and J. H, THOMAS, 1996 Genetic analysis of the roles of daf-28 and age-1 in regulating Caenorhabditis elegans dauer formation. Genetics 143: 1193-1205.
    • (1996) Genetics , vol.143 , pp. 1193-1205
    • Malone, E.A.1    Inoue, T.2    Thomas, J.H.3
  • 37
    • 0029920370 scopus 로고    scopus 로고
    • Genetic analysis of ageing: Role of oxidative damage and environmental stresses
    • MARTIN, G. M., S. N. AUSTAD and T. E. JOHNSON, 1996 Genetic analysis of ageing: role of oxidative damage and environmental stresses. Nat. Genet. 13: 25-34.
    • (1996) Nat. Genet. , vol.13 , pp. 25-34
    • Martin, G.M.1    Austad, S.N.2    Johnson, T.E.3
  • 38
    • 0026053020 scopus 로고
    • A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans
    • MARUYAMA, I. N., and S. BRENNER, 1991 A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 88: 5729-5733.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5729-5733
    • Maruyama, I.N.1    Brenner, S.2
  • 39
    • 0034284973 scopus 로고    scopus 로고
    • Extension of life-span with superoxide dismutase/catalase mimetics
    • MELOV, S., J. RAVENSCROFT, S. MALIK, M. S. GILL, D. W. WALKER et al., 2000 Extension of life-span with superoxide dismutase/catalase mimetics. Science 289: 1567-1569.
    • (2000) Science , vol.289 , pp. 1567-1569
    • Melov, S.1    Ravenscroft, J.2    Malik, S.3    Gill, M.S.4    Walker, D.W.5
  • 40
    • 0033581704 scopus 로고    scopus 로고
    • The p66shc adaptor protein controls oxidative stress response and life span in mammals
    • MIGLIACCIO, E., M. GIORGIO, S. MELE, G. PELECCI, P. REBOLDI et al., 1999 The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402: 309-313.
    • (1999) Nature , vol.402 , pp. 309-313
    • Migliaccio, E.1    Giorgio, M.2    Mele, S.3    Pelecci, G.4    Reboldi, P.5
  • 41
    • 0029768753 scopus 로고    scopus 로고
    • A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
    • MORRIS, J. Z., H. A. TISSENBAUM and G. RUVKUN, 1996 A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 382: 536-539.
    • (1996) Nature , vol.382 , pp. 536-539
    • Morris, J.Z.1    Tissenbaum, H.A.2    Ruvkun, G.3
  • 42
    • 0030014296 scopus 로고    scopus 로고
    • A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans
    • MURAKAMI, S., and T. E. JOHNSON, 1996 A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans. Genetics 143: 1207-1218.
    • (1996) Genetics , vol.143 , pp. 1207-1218
    • Murakami, S.1    Johnson, T.E.2
  • 43
    • 0031939721 scopus 로고    scopus 로고
    • Functional properties of the unc-64 gene encoding a Caenorhabditis elegans syntaxin
    • OGAWA, H., S. HARADA, T. SASSA, H. YAMAMOTO and R. HOSONO, 1998 Functional properties of the unc-64 gene encoding a Caenorhabditis elegans syntaxin. J. Biol. Chem. 273: 2192-2198.
    • (1998) J. Biol. Chem. , vol.273 , pp. 2192-2198
    • Ogawa, H.1    Harada, S.2    Sassa, T.3    Yamamoto, H.4    Hosono, R.5
  • 44
    • 0030659557 scopus 로고    scopus 로고
    • The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • OGG, S., S. PARADIS, S. GOTTLIEB, G. I. PATTERSON, L. LEE et al., 1997 The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389: 994-999.
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1    Paradis, S.2    Gottlieb, S.3    Patterson, G.I.4    Lee, L.5
  • 45
    • 0033151613 scopus 로고    scopus 로고
    • A PDKI homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
    • PARADIS, S., M. AILION, A. TOKER, J. H. THOMAS and G. RUVKUN, 1999 A PDKI homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans. Genes Dev. 13: 1438-1452.
    • (1999) Genes Dev. , vol.13 , pp. 1438-1452
    • Paradis, S.1    Ailion, M.2    Toker, A.3    Thomas, J.H.4    Ruvkun, G.5
  • 46
    • 0035868890 scopus 로고    scopus 로고
    • Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family
    • PIERCE, S. B., M. COSTA, R. WISOTZKEY, S. DEVADHAR, S. A. HOMBURGER et al., 2001 Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. Genes Dev. 15: 672-686.
    • (2001) Genes Dev. , vol.15 , pp. 672-686
    • Pierce, S.B.1    Costa, M.2    Wisotzkey, R.3    Devadhar, S.4    Homburger, S.A.5
  • 47
    • 10544256181 scopus 로고    scopus 로고
    • Control of C. elegans larval development by neuronal expression of a TGF-beta homolog
    • REN, P., C. S. LIM, R. JOHNSON, P. S. ALBERT, D. PILGRIM et al., 1996 Control of C. elegans larval development by neuronal expression of a TGF-beta homolog. Science 274: 1389-1391.
    • (1996) Science , vol.274 , pp. 1389-1391
    • Ren, P.1    Lim, C.S.2    Johnson, R.3    Albert, P.S.4    Pilgrim, D.5
  • 48
    • 0033349884 scopus 로고    scopus 로고
    • UNC-13 is required for synaptic vesicle fusion in C. elegans
    • RICHMOND, J. E., W. S. DAVIS and E. M. JORGENSEN, 1999 UNC-13 is required for synaptic vesicle fusion in C. elegans. Nat. Neurosci. 2: 959-964.
    • (1999) Nat. Neurosci. , vol.2 , pp. 959-964
    • Richmond, J.E.1    Davis, W.S.2    Jorgensen, E.M.3
  • 49
    • 0001104583 scopus 로고    scopus 로고
    • Genetic and enviromental regulation of dauer larva development
    • edited by D. L. Riddle, T. Blumenthal, B. J. Meyer and J. R. Priess. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • RIDDLE, D. L., and P. S. ALBERT, 1997 Genetic and enviromental regulation of dauer larva development, pp. 739-768 in C. elegans II, edited by D. L. RIDDLE, T. BLUMENTHAL, B. J. MEYER and J. R. PRIESS. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1997) C. elegans II , pp. 739-768
    • Riddle, D.L.1    Albert, P.S.2
  • 50
    • 0019496482 scopus 로고
    • Interacting genes in nematode dauer larva formation
    • RIDDLE, D. L., M. M. SWANSON and P. S. ALBERT, 1981 Interacting genes in nematode dauer larva formation. Nature 290: 668-671.
    • (1981) Nature , vol.290 , pp. 668-671
    • Riddle, D.L.1    Swanson, M.M.2    Albert, P.S.3
  • 51
    • 0022037074 scopus 로고
    • Mutagenesis in Caenorhabditis elegans. II. A spectrum of mutational events induced with 1500 r of gamma-radiation
    • ROSENBLUTH, R. E., C. CUDDEFORD and D. L. BAILLIE, 1985 Mutagenesis in Caenorhabditis elegans. II. A spectrum of mutational events induced with 1500 r of gamma-radiation. Genetics 109: 493-511.
    • (1985) Genetics , vol.109 , pp. 493-511
    • Rosenbluth, R.E.1    Cuddeford, C.2    Baillie, D.L.3
  • 52
    • 0031869652 scopus 로고    scopus 로고
    • The Caenorhabditis elegans unc-64 locus encodes a syntaxin that interacts genetically with synaptobrevin
    • SAIFEE, O., L. WEI, and M. L. NONET, 1998 The Caenorhabditis elegans unc-64 locus encodes a syntaxin that interacts genetically with synaptobrevin. Mol. Biol. Cell 9: 1235-1252.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 1235-1252
    • Saifee, O.1    Wei, L.2    Nonet, M.L.3
  • 53
    • 0033912987 scopus 로고    scopus 로고
    • Using stress resistance to isolate novel longevity mutations in Caenorhabditis elegans
    • SAMPAYO, J. N.,N. L. JENKlNS and G. J. LITHGOW, 2000 Using stress resistance to isolate novel longevity mutations in Caenorhabditis elegans. Ann. NY Acad. Sci. 908: 324-326.
    • (2000) Ann. NY Acad. Sci. , vol.908 , pp. 324-326
    • Sampayo, J.N.1    Jenklns, N.L.2    Lithgow, G.J.3
  • 54
    • 0033564050 scopus 로고    scopus 로고
    • Regulation of the UNC-18-Caenorhabditis elegans syntaxin complex by UNC-13
    • SASSA, T., S. HARADA, H. OGAWA, J. B. RAND, I. N. MARUYAMA et al., 1999 Regulation of the UNC-18-Caenorhabditis elegans syntaxin complex by UNC-13. J. Neurosci. 19: 4772-4777.
    • (1999) J. Neurosci. , vol.19 , pp. 4772-4777
    • Sassa, T.1    Harada, S.2    Ogawa, H.3    Rand, J.B.4    Maruyama, I.N.5
  • 55
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • SOHAL, R. S., and R. WEINDRUCH, 1996 Oxidative stress, caloric restriction, and aging. Science 273: 59-63.
    • (1996) Science , vol.273 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2
  • 56
    • 0028896987 scopus 로고
    • Mutations affecting the chemosensory neurons of Caenorhabditis elegans
    • STARICH, T. A., R. K. HERMAN, C. K. KARI, W. H. YEH, W. S. SCHACKWITZ et al., 1995 Mutations affecting the chemosensory neurons of Caenorhabditis elegans. Genetics 139: 171-188.
    • (1995) Genetics , vol.139 , pp. 171-188
    • Starich, T.A.1    Herman, R.K.2    Kari, C.K.3    Yeh, W.H.4    Schackwitz, W.S.5
  • 57
    • 0016067224 scopus 로고
    • The DNA of Caenorhabditis elegans
    • SULSTON, J. E., and S. BRENNER, 1974 The DNA of Caenorhabditis elegans. Genetics 77: 95-104.
    • (1974) Genetics , vol.77 , pp. 95-104
    • Sulston, J.E.1    Brenner, S.2
  • 58
    • 0035815445 scopus 로고    scopus 로고
    • A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
    • TATAR, M., A. KOPELMAN, D. EPSTEIN, M. P. Tu, C. M. YIN et al., 2001 A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 292: 107-110.
    • (2001) Science , vol.292 , pp. 107-110
    • Tatar, M.1    Kopelman, A.2    Epstein, D.3    Tu, M.P.4    Yin, C.M.5
  • 59
    • 0028803718 scopus 로고
    • The gerontogenes age-1 and daf-2 determine metabolic rate potential in aging Caenorhabditis elegans
    • VANFLETEREN, J. R., and A. DE VREESE, 1995 The gerontogenes age-1 and daf-2 determine metabolic rate potential in aging Caenorhabditis elegans. FASEB J. 9: 1355-1361.
    • (1995) FASEB J. , vol.9 , pp. 1355-1361
    • Vanfleteren, J.R.1    De Vreese, A.2
  • 60
    • 0033613204 scopus 로고    scopus 로고
    • Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate
    • VAN VOORHIES, W. A., and S. WARD, 1999 Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate. Proc. Natl. Acad. Sci. USA 96: 11399-11403.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11399-11403
    • Van Voorhies, W.A.1    Ward, S.2
  • 61
    • 0031784011 scopus 로고    scopus 로고
    • A relationship between thermotolerance and longevity in Caenorhabditis elegans
    • WALKER, G. A., D. W. WALKER and G. J. LITHGOW, 1998 A relationship between thermotolerance and longevity in Caenorhabditis elegans. J. Invest. Dermatol. Symp. Proc. 3: 6-10.
    • (1998) J. Invest. Dermatol. Symp. Proc. , vol.3 , pp. 6-10
    • Walker, G.A.1    Walker, D.W.2    Lithgow, G.J.3
  • 62
    • 0346668317 scopus 로고    scopus 로고
    • Insulin receptor substrate and p55 orthologous adaptor proteins function in the C. elegans daf-2/insulin-like signaling pathway
    • WOLKOW, C. A., M. J. MUÑOZ, D. L. RIDDLE and G. RUVKUN, 2002 Insulin receptor substrate and p55 orthologous adaptor proteins function in the C. elegans daf-2/insulin-like signaling pathway. J. Biol. Chem. 277: 49591-49597.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49591-49597
    • Wolkow, C.A.1    Muñoz, M.J.2    Riddle, D.L.3    Ruvkun, G.4
  • 63
    • 0032936317 scopus 로고    scopus 로고
    • Characterization of a life-extending mutation in age-2, a new aging gene in Caenorhabditis elegans
    • YANG, Y., and D. L. WILSON, 1999 Characterization of a life-extending mutation in age-2, a new aging gene in Caenorhabditis elegans. J. Gerontol. A Biol. Sci. Med. Sci. 54: B137-B142.
    • (1999) J. Gerontol. A Biol. Sci. Med. Sci. , vol.54
    • Yang, Y.1    Wilson, D.L.2
  • 64
    • 0033979686 scopus 로고    scopus 로고
    • Isolating aging mutants: A novel method yields three strains of the nematode Caenorhabditis elegans with extended life spans
    • YANG, Y., and D. L. WILSON, 2000 Isolating aging mutants: a novel method yields three strains of the nematode Caenorhabditis elegans with extended life spans. Mech. Ageing Dev. 113: 101-116.
    • (2000) Mech. Ageing Dev. , vol.113 , pp. 101-116
    • Yang, Y.1    Wilson, D.L.2
  • 65
    • 0034731521 scopus 로고    scopus 로고
    • Munc-18 associates with syntaxin and serves as a negative regulator of exocytosis in the pancreatic beta-cell
    • ZHANG, W., A. EFANOV, S. N. YANG, G. FRIED, S. KOLARE et al., 2000 Munc-18 associates with syntaxin and serves as a negative regulator of exocytosis in the pancreatic beta-cell. J. Biol. Chem. 275: 41521-41527.
    • (2000) J. Biol. Chem. , vol.275 , pp. 41521-41527
    • Zhang, W.1    Efanov, A.2    Yang, S.N.3    Fried, G.4    Kolare, S.5


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