Mitochondrial decay in hepatocytes from old rats: Membrane potential declines, heterogeneity and oxidants increase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 7, 1997, Pages 3064-3069

  Hagen, Tory M ^a   Yowe, David L ^a   Bartholomew, James C ^b   Wehr, Carol M ^a   Do, Katherine L ^a   Park, Jin Y ^a   Ames, Bruce N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

aging; centrifugal cell elutriation; flow cytometry; mitochondrial DNA deletions; rhodamine 123

Indexed keywords

FLUORESCEIN DERIVATIVE; MITOCHONDRIAL DNA; OXIDIZING AGENT; RHODAMINE 123; TETRAPHENYLPHOSPHONIUM;

AGING; ANIMAL CELL; ARTICLE; CELL ISOLATION; CELL SUBPOPULATION; CENTRIFUGATION; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE; GENE DELETION; LIVER CELL; LIVER MITOCHONDRION; MALE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTON MOTIVE FORCE; RAT;

AGING; ANIMALS; DNA, MITOCHONDRIAL; FLOW CYTOMETRY; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA, LIVER; OXIDANTS; OXYGEN; RATS; RATS, INBRED F344; SEQUENCE DELETION;

ANIMALIA;

EID: 0030915483     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.7.3064     Document Type: Article

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