-
1
-
-
33644788087
-
Dendritic cells in asthma: A function beyond sensitization
-
Sep
-
van Rijt LS, Lambrecht BN. Dendritic cells in asthma: a function beyond sensitization. Clin Exp Allergy. 2005 Sep;35(9):1125-1134
-
(2005)
Clin Exp Allergy
, vol.35
, Issue.9
-
-
Van Rijt, L.S.1
Lambrecht, B.N.2
-
2
-
-
0032968706
-
Immunologic basis of antigen-induced airway hyperresponsiveness
-
DOI 10.1146/annurev.immunol.17.1.255
-
2. Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol. 1999;17:255-281 (Pubitemid 29241125)
-
(1999)
Annual Review of Immunology
, vol.17
-
-
Wills-Karp, M.1
-
3
-
-
47949119866
-
Pathogenesis of asthma
-
Jun
-
Holgate ST. Pathogenesis of asthma. Clin Exp Allergy. 2008 Jun;38(6):872-897
-
(2008)
Clin Exp Allergy
, vol.38
, Issue.6
-
-
Holgate, S.T.1
-
4
-
-
0025285280
-
Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation
-
Mar 1
-
June CH, Fletcher MC, Ledbetter JA, Samelson LE. Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation. J Immunol. 1990 Mar 1;144(5): 1591-1599
-
(1990)
J Immunol
, vol.144
, Issue.5
-
-
June, C.H.1
Fletcher, M.C.2
Ledbetter, J.A.3
Samelson, L.E.4
-
5
-
-
0025094356
-
Inhibition of tyrosine phosphorylation prevents T-cell receptormediated signal transduction
-
Oct
-
June CH, Fletcher MC, Ledbetter JA, Schieven GL, Siegel JN, Phillips AF, Samelson LE. Inhibition of tyrosine phosphorylation prevents T-cell receptormediated signal transduction. Proc Natl Acad Sci USA. 1990 Oct;87(19):7722-7726
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, Issue.19
-
-
June, C.H.1
Fletcher, M.C.2
Ledbetter, J.A.3
Schieven, G.L.4
Siegel, J.N.5
Phillips, A.F.6
Samelson, L.E.7
-
6
-
-
0025332477
-
T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation
-
Mar 30
-
Mustehn T, Coggeshall KM, Isakov N, Altman A. T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation. Science. 1990 Mar 30;247(4950):1584-1587
-
(1990)
Science
, vol.247
, Issue.4950
-
-
Mustehn, T.1
Coggeshall, K.M.2
Isakov, N.3
Altman, A.4
-
7
-
-
0025047808
-
Tyrosine phosphorylation is an obligatory event in IL-2 secretion
-
7. Stanley JB, Gorczynski R, Huang CK, Love J, Mills GB. Tyrosine phosphorylation is an obligatory event in IL-2 secretion. J Immunol. 1990 Oct 1;145(7):2189-2198 (Pubitemid 20343384)
-
(1990)
Journal of Immunology
, vol.145
, Issue.7
-
-
Stanley, J.B.1
Gorczynski, R.2
Huang, C.-K.3
Love, J.4
Mills, G.B.5
-
8
-
-
33750299450
-
Protein tyrosine phosphatases: From genes, to function, to disease
-
Nov
-
Tonks NK. Protein tyrosine phosphatases: from genes, to function, to disease. Nat Rev Mol Cell Biol. 2006 Nov;7(11):833-846
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.11
-
-
Tonks, N.K.1
-
9
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Oct 13
-
Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 2000 Oct 13;103(2):211-225
-
(2000)
Cell
, vol.103
, Issue.2
-
-
Schlessinger, J.1
-
10
-
-
0037204953
-
A road map for those who don't know JAK-STAT
-
May 31
-
Aaronson DS, Horvath CM. A road map for those who don't know JAK-STAT. Science. 2002 May 31;296(5573):1653-1655
-
(2002)
Science
, vol.296
, Issue.5573
-
-
Aaronson, D.S.1
Horvath, C.M.2
-
11
-
-
0242659390
-
Mast cell signal transduction from the high-affinity IgE receptor
-
Dec
-
Siraganian RP. Mast cell signal transduction from the high-affinity IgE receptor. Curr Opin Immunol. 2003 Dec;15(6):639-646
-
(2003)
Curr Opin Immunol
, vol.15
, Issue.6
-
-
Siraganian, R.P.1
-
12
-
-
3042613385
-
Kinase targets and inhibitors for the treatment of airway inflammatory diseases: The next generation of drugs for severe asthma and COPD?
-
Adcock IM, Caramori G. Kinase targets and inhibitors for the treatment of airway inflammatory diseases: the next generation of drugs for severe asthma and COPD? BioDrugs. 2004;18(3):167-180
-
(2004)
BioDrugs
, vol.18
, Issue.3
-
-
Adcock, I.M.1
Caramori, G.2
-
14
-
-
0028964465
-
Cytokine signaling through nonreceptor protein tyrosine kinases
-
Apr 14
-
Taniguchi T. Cytokine signaling through nonreceptor protein tyrosine kinases. Science. 1995 Apr 14;268(5208):251-255
-
(1995)
Science
, vol.268
, Issue.5208
-
-
Taniguchi, T.1
-
15
-
-
0037382808
-
Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma
-
DOI 10.1172/JCI200316440
-
15. Kwak YG, Song CH, Yi HK, Hwang PH, Kim JS, Lee KS, Lee YC. Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma. J Clin Invest. 2003 Apr;111(7):1083-1092 (Pubitemid 36397485)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.7
-
-
Kwak, Y.-G.1
Song, C.H.2
Yi, H.K.3
Hwang, P.H.4
Kim, J.-S.5
Lee, K.S.6
Lee, Y.C.7
-
16
-
-
0037251603
-
Src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation
-
DOI 10.1172/JCI200315719
-
16. Kamata T, Yamashita M, Kimura M, Murata K, Inami M, Shimizu C, Sugaya K, Wang CR, Taniguchi M, Nakayama T. Src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation. J Clin Invest. 2003 Jan;111(1):109-119 (Pubitemid 36134854)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.1
-
-
Kamata, T.1
Yamashita, M.2
Kimura, M.3
Murata, K.4
Inami, M.5
Shimizu, C.6
Sugaya, K.7
Wang, C.-R.8
Taniguchi, M.9
Nakayama, T.10
-
17
-
-
65349166874
-
A critical role of SHP-1 in regulation of type 2 inflammation in the lung
-
May
-
Oh SY, Zheng T, Kim YK, Cohn L, Homer RJ, McKenzie AN, Zhu Z. A critical role of SHP-1 in regulation of type 2 inflammation in the lung. Am J Respir Cell Mol Biol. 2009 May;40(5):568-574
-
(2009)
Am J Respir Cell Mol Biol
, vol.40
, Issue.5
-
-
Oh, S.Y.1
Zheng, T.2
Kim, Y.K.3
Cohn, L.4
Homer, R.J.5
McKenzie, A.N.6
Zhu, Z.7
-
18
-
-
0043075805
-
Heterogeneity in the pathology and treatment of asthma
-
Aug
-
Peters SP. Heterogeneity in the pathology and treatment of asthma. Am J Med. 2003 Aug 18;115 Suppl 3A:49S-54S.
-
(2003)
Am J Med
, vol.18
, Issue.115 SUPPL.
-
-
Peters, S.P.1
-
19
-
-
0031866839
-
Alpha-1 antitrypsin up-regulates human B cell differentiation selectively into IgE- And lgG4-secreting cells
-
DOI 10.1002/(SICI)1521-4141(199806)28:06<1815::AID-IMMU1815>3.0. CO;2-5
-
19. Jeannin P, Lecoanet-Henchoz S, Delneste Y, Gauchat JF, Bonnefoy JY. Alpha-1 antitrypsin up-regulates human B cell differentiation selectively into IgE-and IgG4-secreting cells. Eur J Immunol. 1998 Jun;28(6):1815-1822 (Pubitemid 28271697)
-
(1998)
European Journal of Immunology
, vol.28
, Issue.6
-
-
Jeannin, P.1
Lecoanet-Henchoz, S.2
Delneste, Y.3
Gauchat, J.-F.4
Bonnefoy, J.-Y.5
-
20
-
-
0029931447
-
Immunoglobulin class switching
-
Apr
-
Stavnezer J. Immunoglobulin class switching. Curr Opin Immunol. 1996 Apr;8(2):199-205.
-
(1996)
Curr Opin Immunol
, vol.8
, Issue.2
-
-
Stavnezer, J.1
-
21
-
-
38849134728
-
Alveolar macrophages from allergic lungs are not committed to a pro-allergic response and can reduce airway hyperresponsiveness following ex vivo culture
-
Mar
-
Pouliot P, Spahr A, Careau E, Turmel V, Bissonnette EY. Alveolar macrophages from allergic lungs are not committed to a pro-allergic response and can reduce airway hyperresponsiveness following ex vivo culture. Clin Exp Allergy. 2008 Mar;38(3):529-538
-
(2008)
Clin Exp Allergy
, vol.38
, Issue.3
-
-
Pouliot, P.1
Spahr, A.2
Careau, E.3
Turmel, V.4
Bissonnette, E.Y.5
-
22
-
-
33646569994
-
Antigen sensitization modulates alveolar macrophage functions in an asthma model
-
DOI 10.1152/ajplung.00219.2005
-
22. Careau E, Proulx LI, Pouliot P, Spahr A, Turmel V, Bissonnette EY. Antigen sensitization modulates alveolar macrophage functions in an asthma model. Am J Physiol Lung Cell Mol Physiol. 2006 May;290(5):L871-L879. (Pubitemid 43725049)
-
(2006)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.290
, Issue.5
-
-
Careau, E.1
Proulx, L.-I.2
Pouliot, P.3
Spahr, A.4
Turmel, V.5
Bissonnette, E.Y.6
-
24
-
-
0034864617
-
Cytokine-directed therapies for asthma
-
Aug
-
Barnes PJ. Cytokine-directed therapies for asthma. J Allergy Clin Immunol. 2001 Aug;108(2 Suppl):S72-S76.
-
(2001)
J Allergy Clin Immunol
, vol.108
, Issue.2 SUPPL.
-
-
Barnes, P.J.1
-
26
-
-
0023898796
-
Late airway responses to antigen challenge in sensitized inbred rats
-
May
-
Eidelman DH, Bellofiore S, Martin JG. Late airway responses to antigen challenge in sensitized inbred rats. Am Rev Respir Dis. 1988 May;137(5):1033-1037
-
(1988)
Am Rev Respir Dis
, vol.137
, Issue.5
-
-
Eidelman, D.H.1
Bellofiore, S.2
Martin, J.G.3
-
27
-
-
0030800586
-
Gelfand EW Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography
-
Sep
-
Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, Gelfand EW Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med. 1997 Sep;156(3 Pt 1:766-75.
-
(1997)
Am J Respir Crit Care Med
, vol.156
, Issue.3 PART 1
-
-
Hamelmann, E.1
Schwarze, J.2
Takeda, K.3
Oshiba, A.4
Larsen, G.L.5
Irvin, C.G.6
-
28
-
-
4444368190
-
The use and misuse of Penh in animal models of lung disease
-
28. Bates J, Irvin C, Brusasco V, Drazen J, Fredberg J, Loring S, Eidelman D, Ludwig M, Macklem P, Martin J, Milic-Emili J, Hantos Z, Hyatt R, Lai-Fook S, Leff A, Solway J, Lutchen K, Suki B, Mitzner W, Pare P, Pride N, Sly P. The use and misuse of Penh in animal models of lung disease. Am J Respir Cell Mol Biol. 2004 Sep;31(3):373-374 (Pubitemid 39180309)
-
(2004)
American Journal of Respiratory Cell and Molecular Biology
, vol.31
, Issue.3
-
-
Bates, J.1
Irvin, C.2
Brusasco, V.3
Drazen, J.4
Fredberg, J.5
Loring, S.6
Eidelman, D.7
Ludwig, M.8
Macklem, P.9
Martin, J.10
Milic-Emili, J.11
Hantos, Z.12
Hyatt, R.13
Lai-Fook, S.14
Leff, A.15
Solway, J.16
Lutchen, K.17
Suki, B.18
Mitzner, W.19
Pare, P.20
Pride, N.21
Sly, P.22
more..
-
30
-
-
42649112362
-
Evolutionarily conserved amino acids that control TCR-MHC interaction
-
DOI 10.1146/annurev.immunol.26.021607.090421
-
30. Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol. 2008;26:171-203. (Pubitemid 351600374)
-
(2008)
Annual Review of Immunology
, vol.26
-
-
Marrack, P.1
Scott-Browne, J.P.2
Dai, S.3
Gapin, L.4
Kappler, J.W.5
-
31
-
-
0033010661
-
Genetic analysis of B cell antigen receptor signaling
-
DOI 10.1146/annurev.immunol.17.1.555
-
31. Kurosaki T. Genetic analysis of B cell antigen receptor signaling. Annu Rev Immunol. 1999;17:555-592 (Pubitemid 29241134)
-
(1999)
Annual Review of Immunology
, vol.17
-
-
Kurosaki, T.1
-
32
-
-
0030890949
-
Initiation and processing of signals from the B cell antigen receptor
-
DOI 10.1146/annurev.immunol.15.1.453
-
32. Reth M, Wienands J. Initiation and processing of signals from the B cell antigen receptor. Annu Rev Immunol. 1997;15:453-479 (Pubitemid 27169289)
-
(1997)
Annual Review of Immunology
, vol.15
-
-
Reth, M.1
Wienands, J.2
-
33
-
-
0035177431
-
Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes
-
DOI 10.1084/jem.193.1.51
-
33. Vermaelen KY, Carro-Muino I, Lambrecht BN, Pauwels RA. Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J Exp Med. 2001 Jan 1;193(1): 51-60. (Pubitemid 32060697)
-
(2001)
Journal of Experimental Medicine
, vol.193
, Issue.1
-
-
Vermaelen, K.Y.1
Carro-Muino, I.2
Lambrecht, B.N.3
Pauwels, R.A.4
-
34
-
-
0141958256
-
2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1
-
34. Hammad H, de Heer HJ, Soullie T, Hoogsteden HC, Trottein F, Lambrecht BN. Prostaglandin D2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1. J Immunol. 2003 Oct 15;171(8):3936-3940 (Pubitemid 37238665)
-
(2003)
Journal of Immunology
, vol.171
, Issue.8
-
-
Hammad, H.1
De Heer, H.J.2
Soullie, T.3
Hoogsteden, H.C.4
Trottein, F.5
Lambrecht, B.N.6
-
35
-
-
0036070857
-
Viral induction of a chronic asthma phenotype and genetic segregation from the acute response
-
DOI 10.1172/JCI200214345
-
35. Walter MJ, Morton JD, Kajiwara N, Agapov E, Holtzman MJ. Viral induction of a chronic asthma phenotype and genetic segregation from the acute response. J Clin Invest. 2002 Jul;110(2):165-175 (Pubitemid 34787353)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.2
-
-
Walter, M.J.1
Morton, J.D.2
Kajiwara, N.3
Agapov, E.4
Holtzman, M.J.5
-
36
-
-
0034307339
-
The Toll receptor family and microbial recognition
-
Oct
-
6. Medzhitov R, Janeway C, Jr. The Toll receptor family and microbial recognition. Trends Microbiol. 2000 Oct;8(10):452-456
-
(2000)
Trends Microbiol
, vol.8
, Issue.10
-
-
Medzhitov, R.1
Janeway Jr., C.2
-
37
-
-
3142720367
-
Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen
-
DOI 10.1084/jem.20040035
-
37. de Heer HJ, Hammad H, Soullie T, Hijdra D, Vos N, Willart MA, Hoogsteden HC, Lambrecht BN. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J Exp Med. 2004 Jul 5;200(1):89-98. (Pubitemid 38924731)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.1
-
-
De Heer, H.J.1
Hammad, H.2
Soullie, T.3
Hijdra, D.4
Vos, N.5
Willart, M.A.M.6
Hoogsteden, H.C.7
Lambrecht, B.N.8
-
38
-
-
42249088234
-
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
-
DOI 10.1084/jem.20071087
-
38. Kool M, Soullie T, van NM, Willart MA, Muskens F, Jung S, Hoogsteden HC, Hammad H, Lambrecht BN. Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells. J Exp Med. 2008 Apr 14;205(4):869-882 (Pubitemid 351549884)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.4
-
-
Kool, M.1
Soullie, T.2
Van Nimwegen, M.3
Willart, M.A.M.4
Muskens, F.5
Jung, S.6
Hoogsteden, H.C.7
Hammad, H.8
Lambrecht, B.N.9
-
39
-
-
56149119563
-
Cutting Edge: Alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome
-
Sep 15
-
Kool M, Petrilli V, De ST, Rolaz A, Hammad H, van NM, Bergen IM, Castillo R, Lambrecht BN, Tschopp J. Cutting Edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. J Immunol. 2008 Sep 15;181(6):3755-3759
-
(2008)
J Immunol
, vol.181
, Issue.6
-
-
Kool, M.1
Petrilli, V.2
De Rolaz A, S.T.3
Hammad, H.4
Van Bergen Im, N.M.5
Castillo, R.6
Lambrecht, B.N.7
Tschopp, J.8
-
40
-
-
7044274793
-
Aluminium compounds for use in vaccines
-
Oct
-
Lindblad EB. Aluminium compounds for use in vaccines. Immunol Cell Biol. 2004 Oct;82(5):497-505.
-
(2004)
Immunol Cell Biol
, vol.82
, Issue.5
-
-
Lindblad, E.B.1
-
41
-
-
0037121946
-
Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen
-
DOI 10.1084/jem.20021340
-
41. Eisenbarth SC, Piggott DA, Huleatt JW, Visintin I, Herrick CA, Bottomly K. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med. 2002 Dec 16;196(12):1645-1651 (Pubitemid 36026476)
-
(2002)
Journal of Experimental Medicine
, vol.196
, Issue.12
-
-
Eisenbarth, S.C.1
Piggott, D.A.2
Huleatt, J.W.3
Visintin, I.4
Herrick, C.A.5
Bottomly, K.6
-
43
-
-
0004916672
-
Immunobiology the immune system in health and disease
-
3rd ed ed. London
-
Janeway C, Travers P. Immunobiology the immune system in health and disease. 3rd ed ed. London: Current Biology; 1997.
-
(1997)
Current Biology
-
-
Janeway, C.1
Travers, P.2
-
45
-
-
0028949152
-
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
-
Mar 10
-
Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 1995 Mar 10;80(5):707-718
-
(1995)
Cell
, vol.80
, Issue.5
-
-
Kuchroo, V.K.1
Das, M.P.2
Brown, J.A.3
Ranger, A.M.4
Zamvil, S.S.5
Sobel, R.A.6
Weiner, H.L.7
Nabavi, N.8
Glimcher, L.H.9
-
46
-
-
0031569258
-
Role of Costimulators in T Cell Differentiation: Studies Using Antigen-Presenting Cells Lacking Expression of CD80 or CD86
-
46. Schweitzer AN, Borriello F, Wong RC, Abbas AK, Sharpe AH. Role of costimulators in T cell differentiation: studies using antigen-presenting cells lacking expression of CD80 or CD86.J Immunol. 1997 Mar 15;158(6):2713-2722 (Pubitemid 127470529)
-
(1997)
Journal of Immunology
, vol.158
, Issue.6
-
-
Schweitzer, A.N.1
Borriello, F.2
Wong, R.C.K.3
Abbas, A.K.4
Sharpe, A.H.5
-
47
-
-
0037103132
-
Early events of TCR signaling are distinct in human Th1 and Th2 cells
-
47. Hannier S, Bitegye C, Demotz S. Early events of TCR signaling are distinct in human Th1 and Th2 cells. J Immunol. 2002 Aug 15;169(4):1904-1911 (Pubitemid 34857653)
-
(2002)
Journal of Immunology
, vol.169
, Issue.4
-
-
Hannier, S.1
Bitegye, C.2
Demotz, S.3
-
48
-
-
0032427721
-
CD4+ T cells can induce airway hyperresponsiveness to allergen challenge in the Brown Norway rat
-
48. Mishima H, Hojo M, Watanabe A, Hamid QA, Martin JG. CD4+ T cells can induce airway hyperresponsiveness to allergen challenge in the brown norway rat. Am J Respir Crit Care Med. 1998 Dec;158(6):1863-1870 (Pubitemid 29008826)
-
(1998)
American Journal of Respiratory and Critical Care Medicine
, vol.158
, Issue.6
-
-
Mishima, H.1
Hojo, M.2
Watanabe, A.3
Hamid, Q.A.4
Martin, J.G.5
-
49
-
-
0033950301
-
Regulation of mast cell signaling through high-affinity IgE receptor by CD45 protein tyrosine phosphatase
-
Feb
-
Murakami K, Sato S, Nagasawa S, Yamashita T. Regulation of mast cell signaling through high-affinity IgE receptor by CD45 protein tyrosine phosphatase. Int Immunol. 2000 Feb;12(2):169-176
-
(2000)
Int Immunol
, vol.12
, Issue.2
-
-
Murakami, K.1
Sato, S.2
Nagasawa, S.3
Yamashita, T.4
-
50
-
-
0029846429
-
CD45 modulates phosphorylation of both autophosphorylation and negative regulatory tyrosines of Lyn in B cells
-
DOI 10.1074/jbc.271.48.30487
-
50. Yanagi S, Sugawara H, Kurosaki M, Sabe H, Yamamura H, Kurosaki T. CD45 modulates phosphorylation of both autophosphorylation and negative regulatory tyrosines of Lyn in B cells. J Biol Chem. 1996 Nov 29;271(48):30487-30492 (Pubitemid 26404055)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.48
-
-
Yanagi, S.1
Sugawara, H.2
Kurosaki, M.3
Sabe, H.4
Yamamura, H.5
Kurosaki, T.6
-
51
-
-
0023818706
-
Molecular and cellular biology of eosinophil differentiation factor (interleukin-5) and its effects on human and mouse B cells
-
Feb
-
Sanderson CJ, Campbell HD, Young IG. Molecular and cellular biology of eosinophil differentiation factor (interleukin-5) and its effects on human and mouse B cells. Immunol Rev. 1988 Feb;102:29-50.
-
(1988)
Immunol Rev
, vol.102
-
-
Sanderson, C.J.1
Campbell, H.D.2
Young, I.G.3
-
52
-
-
0028673423
-
Interleukin-5 and its receptor system: Implications in the immune system and inflammation
-
Takatsu K, Takaki S, Hitoshi Y. Interleukin-5 and its receptor system: implications in the immune system and inflammation. Adv Immunol. 1994;57:145-190
-
(1994)
Adv Immunol
, vol.57
-
-
Takatsu, K.1
Takaki, S.2
Hitoshi, Y.3
-
54
-
-
49749165001
-
The Phosphorylase b to a converting enzyme of rabbit skeletal muscle
-
Apr
-
Krebs EG, Fischer EH. The Phosphorylase b to a converting enzyme of rabbit skeletal muscle. Biochim Biophys Acta. 1956 Apr;20(1):150-157
-
(1956)
Biochim Biophys Acta
, vol.20
, Issue.1
-
-
Krebs, E.G.1
Fischer, E.H.2
-
55
-
-
0031026008
-
The protein kinases of budding yeast: Six score and more
-
Jan
-
Hunter T, Plowman GD. The protein kinases of budding yeast: six score and more. Trends Biochem Sci. 1997 Jan;22(1):18-22.
-
(1997)
Trends Biochem Sci
, vol.22
, Issue.1
-
-
Hunter, T.1
Plowman, G.D.2
-
56
-
-
28544438330
-
Role of ITAM-containing adapter proteins and their receptors in the immune system and bone
-
Dec
-
Humphrey MB, Lanier LL, Nakamura MC. Role of ITAM-containing adapter proteins and their receptors in the immune system and bone. Immunol Rev. 2005 Dec;208:50-65.
-
(2005)
Immunol Rev
, vol.208
-
-
Humphrey, M.B.1
Lanier, L.L.2
Nakamura, M.C.3
-
57
-
-
2942581416
-
Protein tyrosine phosphatases in the human genome
-
Jun 11
-
Alonso A, Sasin J, Bottini N, Friedberg I, Friedberg I, Osterman A, Godzik A, Hunter T, Dixon J, Mustelin T. Protein tyrosine phosphatases in the human genome. Cell. 2004 Jun 11;117(6):699-711.
-
(2004)
Cell
, vol.117
, Issue.6
-
-
Alonso, A.1
Sasin, J.2
Bottini, N.3
Friedberg, I.4
Friedberg, I.5
Osterman, A.6
Godzik, A.7
Hunter, T.8
Dixon, J.9
Mustelin, T.10
-
58
-
-
0037032835
-
The protein kinase complement of the human genome
-
Dec 6
-
Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. The protein kinase complement of the human genome. Science. 2002 Dec 6;298(5600): 1912-1934
-
(2002)
Science
, vol.298
, Issue.5600
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
59
-
-
0141507943
-
Corticosteroid-insensitive asthma: Molecular mechanisms
-
Sep
-
Adcock IM, Lane SJ. Corticosteroid-insensitive asthma: molecular mechanisms. J Endocrinol. 2003 Sep;178(3):347-355
-
(2003)
J Endocrinol
, vol.178
, Issue.3
-
-
Adcock, I.M.1
Lane, S.J.2
-
60
-
-
0037248247
-
Update on glucocorticoid action and resistance
-
Jan
-
Leung DY, Bloom JW. Update on glucocorticoid action and resistance. J Allergy Clin Immunol. 2003 Jan;111(1):3-22.
-
(2003)
J Allergy Clin Immunol
, vol.111
, Issue.1
-
-
Leung, D.Y.1
Bloom, J.W.2
-
61
-
-
20444445863
-
Altered protein tyrosine phosphorylation in asthmatic bronchial epithelium
-
Jun
-
Hamilton LM, Puddicombe SM, Dearman RJ, Kimber I, Sandstrom T, Wallin A, Howarth PH, Holgate ST, Wilson SJ, Davies DE. Altered protein tyrosine phosphorylation in asthmatic bronchial epithelium. Eur Respir J. 2005 Jun;25(6):978-985
-
(2005)
Eur Respir J
, vol.25
, Issue.6
-
-
Hamilton, L.M.1
Puddicombe, S.M.2
Dearman, R.J.3
Kimber, I.4
Sandstrom, T.5
Wallin, A.6
Howarth, P.H.7
Holgate, S.T.8
Wilson, S.J.9
Davies, D.E.10
-
62
-
-
64149087970
-
House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
-
Apr
-
Hammad H, Chieppa M, Perros F, Willart MA, Germain RN, Lambrecht BN. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat Med. 2009 Apr;15(4):410-416
-
(2009)
Nat Med
, vol.15
, Issue.4
-
-
Hammad, H.1
Chieppa, M.2
Perros, F.3
Willart, M.A.4
Germain, R.N.5
Lambrecht, B.N.6
-
63
-
-
0037438682
-
Antiinflammatory effects of genistein, a tyrosine kinase inhibitor, on a guinea pig model of asthma
-
DOI 10.1164/rccm.200205-420OC
-
63. Duan W, Kuo IC, Selvarajan S, Chua KY, Bay BH, Wong WS. Antiinflammatory effects of genistein, a tyrosine kinase inhibitor, on a guinea pig model of asthma. Am J Respir Crit Care Med. 2003 Jan 15;167(2):185-192 (Pubitemid 36076078)
-
(2003)
American Journal of Respiratory and Critical Care Medicine
, vol.167
, Issue.2
-
-
Duan, W.1
Kuo, I.C.2
Selvarajan, S.3
Chua, K.Y.4
Bay, B.H.5
Wong, W.S.F.6
-
64
-
-
0026570774
-
Anti-IL-5 monoclonal antibody inhibits aEergic late phase bronchial eosinophiEa in guinea pigs: A therapeutic approach
-
Jan 28
-
Chand N, Harrison JE, Rooney S, Pillar J, Jakubicki R, Nolan K, Diamantis W, Sofia RD. Anti-IL-5 monoclonal antibody inhibits aEergic late phase bronchial eosinophiEa in guinea pigs: a therapeutic approach. Eur J Pharmacol. 1992 Jan 28;211(1):121-123
-
(1992)
Eur J Pharmacol
, vol.211
, Issue.1
-
-
Chand, N.1
Harrison, J.E.2
Rooney, S.3
Pillar, J.4
Jakubicki, R.5
Nolan, K.6
Diamantis, W.7
Sofia, R.D.8
-
65
-
-
0026669245
-
Interleukin-5 modulates eosinophil accumulation in allergic guinea pig lung
-
Jul
-
Gulbenkian AR, Egan RW, Fernandez X, Jones H, Kreutner W, Kung T, Payvandi F, Sullivan L, Zurcher JA, Watnick AS. Interleukin-5 modulates eosinophil accumulation in allergic guinea pig lung. Am Rev Respir Dis. 1992 Jul;146(1):263-266
-
(1992)
Am Rev Respir Dis
, vol.146
, Issue.1
-
-
Gulbenkian, A.R.1
Egan, R.W.2
Fernandez, X.3
Jones, H.4
Kreutner, W.5
Kung, T.6
Payvandi, F.7
Sullivan, L.8
Zurcher, J.A.9
Watnick, A.S.10
-
66
-
-
0027469716
-
Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs
-
Mar
-
van Oosterhout AJ, Ladenius AR, Savelkoul HF, Van A, I, Delsman KC, Nijkamp FP. Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs. Am Rev Respir Dis. 1993 Mar;147(3):548-552
-
(1993)
Am Rev Respir Dis
, vol.147
, Issue.3
-
-
Van Oosterhout, A.J.1
Ladenius, A.R.2
Savelkoul, H.F.3
Van I, A.4
Delsman, K.C.5
Nijkamp, F.P.6
-
67
-
-
0027729739
-
Egan RW, Kreutner W Inhibitory effect of the TRFK-5 anti-IL-5 antibody in a guinea pig model of asthma
-
Dec
-
Mauser PJ, Pitman A, Witt A, Fernandez X, Zurcher J, Kung T, Jones H, Watnick AS, Egan RW, Kreutner W Inhibitory effect of the TRFK-5 anti-IL-5 antibody in a guinea pig model of asthma. Am Rev Respir Dis. 1993 Dec;148(6 Pt 1):1623-1627
-
(1993)
Am Rev Respir Dis
, vol.148
, Issue.6 PART 1
-
-
Mauser, P.J.1
Pitman, A.2
Witt, A.3
Fernandez, X.4
Zurcher, J.5
Kung, T.6
Jones, H.7
Watnick, A.S.8
-
68
-
-
0036843836
-
Characterization of YM-90709 as a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor
-
Nov
-
Morokata T, Ida K, Yamada T. Characterization of YM-90709 as a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor. Int Immunopharmacol. 2002 Nov;2(12): 1693-1702
-
(2002)
Int Immunopharmacol
, vol.2
, Issue.12
-
-
Morokata, T.1
Ida, K.2
Yamada, T.3
-
69
-
-
0033565287
-
A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation, survival, and airway eosinophilic inflammation
-
69. Adachi T, Stafford S, Sur S, Alam R. A novel Lynbinding peptide inhibitor blocks eosinophU differentiation, survival, and airway eosinophilic inflammation. J Immunol. 1999 Jul 15;163(2):939-946 (Pubitemid 29328105)
-
(1999)
Journal of Immunology
, vol.163
, Issue.2
-
-
Adachi, T.1
Stafford, S.2
Sur, S.3
Alam, R.4
-
70
-
-
22544465537
-
Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity
-
70. Beavitt SJ, Harder KW, Kemp JM, Jones J, Quilici C, Casagranda F, Lam E, Turner D, Brennan S, Sly PD, Tarlinton DM, Anderson GP, Hibbs ML. Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity. J Immunol. 2005 Aug 1;175(3): 1867-1875 (Pubitemid 41023093)
-
(2005)
Journal of Immunology
, vol.175
, Issue.3
-
-
Beavitt, S.-J.E.1
Harder, K.W.2
Kemp, J.M.3
Jones, J.4
Quilici, C.5
Casagranda, F.6
Lam, E.7
Turner, D.8
Brennan, S.9
Sly, P.D.10
Tarlinton, D.M.11
Anderson, G.P.12
Hibbs, M.L.13
-
71
-
-
0035496902
-
Transduction of a dominant negative H-Ras into human eosinophils attenuates extracellular signal-regulated kinase activation and interleukin-5-mediated cell viability
-
Oct 1
-
Hall DJ, Cui J, Bates ME, Stout BA, Koenderman L, Coffer PJ, Bertics PJ. Transduction of a dominant negative H-Ras into human eosinophils attenuates extracellular signal-regulated kinase activation and interleukin-5-mediated cell viability. Blood. 2001 Oct 1;98(7):2014-2021
-
(2001)
Blood
, vol.98
, Issue.7
-
-
Hall, D.J.1
Cui, J.2
Bates, M.E.3
Stout, B.A.4
Koenderman, L.5
Coffer, P.J.6
Bertics, P.J.7
-
72
-
-
0032698075
-
Cell survival promoted by the Ras MAPK signaling pathway by transcription-dependent and -independent mechanisms
-
Nov 12
-
Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME. Cell survival promoted by the Ras MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science. 1999 Nov 12;286(5443):1358-1362
-
(1999)
Science
, vol.286
, Issue.5443
-
-
Bonni, A.1
Brunet, A.2
West, A.E.3
Datta, S.R.4
Takasu, M.A.5
Greenberg, M.E.6
-
73
-
-
0032479926
-
Lyn, Jak2, and Raf-1 kinases are critical for the antiapoptotic effect of interleukin 5, whereas only Raf-1 kinase is essential for eosinophil activation and degranulation
-
DOI 10.1084/jem.188.3.421
-
73. Pazdrak K, Olszewska-Pazdrak B, Stafford S, Garofalo RP, Alam R. Lyn, Jak2, and Raf-1 kinases are critical for the antiapoptotic effect of interleukin 5, whereas only Raf-1 kinase is essential for eosinophil activation and degranulation. J Exp Med. 1998 Aug 3;188(3):421-429 (Pubitemid 28369132)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.3
-
-
Pazdrak, K.1
Olszewska-Pazdrak, B.2
Stafford, S.3
Garofalo, R.P.4
Alam, R.5
-
74
-
-
0034595097
-
Blockade of JAK2 by tyrphostin AG-490 inhibits antigen-induced eosinophil recruitment into the mouse airways
-
Apr 2
-
Kumano K, Nakao A, Nakajima H, Miike S, Kurasawa K, Saito Y, Iwamoto I. Blockade of JAK2 by tyrphostin AG-490 inhibits antigen-induced eosinophil recruitment into the mouse airways. Biochem Biophys Res Commun. 2000 Apr 2;270(1):209-214
-
(2000)
Biochem Biophys Res Commun
, vol.270
, Issue.1
-
-
Kumano, K.1
Nakao, A.2
Nakajima, H.3
Miike, S.4
Kurasawa, K.5
Saito, Y.6
Iwamoto, I.7
-
75
-
-
0242332186
-
Prevention of organ aEograft rejection by a specific Janus kinase 3 inhibitor
-
Oct 31
-
Changehan PS, Flanagan ME, Ball DJ, Kent CR, Magnuson KS, Martin WH, Rizzuti BJ, Sawyer PS, Perry BD, Brissette WH, McCurdy SP, Kudlacz EM, Conklyn MJ, Elliott EA, Koslov ER, Fisher MB, Strelevitz TJ, Yoon K, Whipple DA, Sun J, Munchhof MJ, Doty JL, Casavant JM, Blumenkopf TA, Hines M, Brown MF, Lillie BM, Subramanyam C, Shang-Poa C, Milici AJ, Beckius GE, Moyer JD, Su C, Woodworth TG, Gaweco AS, Beals CR, Littman BH, Fisher DA, Smith JF, Zagouras P, Magna HA, Saltarelli MJ, Johnson KS, Nelms LF, Des Etages SG, Hayes LS, Kawabata TT, Finco-Kent D, Baker DL, Larson M, Si MS, Paniagua R, Higgins J, Holm B, Reitz B, Zhou YJ, Morris RE, O'Shea JJ, Borie DC. Prevention of organ aEograft rejection by a specific Janus kinase 3 inhibitor. Science. 2003 Oct 31;302(5646):875-878
-
(2003)
Science
, vol.302
, Issue.5646
-
-
Changehan, P.S.1
Flanagan, M.E.2
Ball, D.J.3
Kent, C.R.4
Magnuson, K.S.5
Martin, W.H.6
Rizzuti, B.J.7
Sawyer, P.S.8
Perry, B.D.9
Brissette, W.H.10
McCurdy, S.P.11
Kudlacz, E.M.12
Conklyn, M.J.13
Elliott, E.A.14
Koslov, E.R.15
Fisher, M.B.16
Strelevitz, T.J.17
Yoon, K.18
Whipple, D.A.19
Sun, J.20
Munchhof, M.J.21
Doty, J.L.22
Casavant, J.M.23
Blumenkopf, T.A.24
Hines, M.25
Brown, M.F.26
Lillie, B.M.27
Subramanyam, C.28
Shang-Poa, C.29
Milici, A.J.30
Beckius, G.E.31
Moyer, J.D.32
Su, C.33
Woodworth, T.G.34
Gaweco, A.S.35
Beals, C.R.36
Littman, B.H.37
Fisher, D.A.38
Smith, J.F.39
Zagouras, P.40
Magna, H.A.41
Saltarelli, M.J.42
Johnson, K.S.43
Nelms, L.F.44
Des Etages, S.G.45
Hayes, L.S.46
Kawabata, T.T.47
Finco-Kent, D.48
Baker, D.L.49
Larson, M.50
Si, M.S.51
Paniagua, R.52
Higgins, J.53
Holm, B.54
Reitz, B.55
Zhou, Y.J.56
Morris, R.E.57
O'Shea, J.J.58
Borie, D.C.59
more..
-
76
-
-
0030030916
-
IL-5 activates a 45-kilodalton mitogen-activated protein (MAP) kinase and Jak-2 tyrosine kinase in human eosinophils
-
Jan 15
-
Bates ME, Bertics PJ, Busse WW. IL-5 activates a 45-kilodalton mitogen-activated protein (MAP) kinase and Jak-2 tyrosine kinase in human eosinophils. J Immunol. 1996 Jan 15;156(2):711-718
-
(1996)
J Immunol
, vol.156
, Issue.2
-
-
Bates, M.E.1
Bertics, P.J.2
Busse, W.W.3
-
77
-
-
0029058148
-
The activation of the Jak-STAT 1 signling pathway by IL-5 in eosinophils
-
Jul 1
-
Pazdrak K, Stafford S, Alam R. The activation of the Jak-STAT 1 signling pathway by IL-5 in eosinophils. J Immunol. 1995 Jul 1;155(1):397-402.
-
(1995)
J Immunol
, vol.155
, Issue.1
-
-
Pazdrak, K.1
Stafford, S.2
Alam, R.3
-
78
-
-
0028953733
-
Interleukin-5 signaling in human eosinophils involves JAK2 tyrosine kinase and Stat1 alpha
-
Mar 15
-
van der BT, Caldenhoven E, Kanters D, Coffer P, Raaijmakers JA, Lammers JW, Koenderman L. Interleukin-5 signaling in human eosinophils involves JAK2 tyrosine kinase and Stat1 alpha. Blood. 1995 Mar 15;85(6):1442-1448
-
(1995)
Blood
, vol.85
, Issue.6
-
-
Van Der, B.T.1
Caldenhoven, E.2
Kanters, D.3
Coffer, P.4
Raaijmakers, J.A.5
Lammers, J.W.6
Koenderman, L.7
-
79
-
-
39149103052
-
The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia
-
Mar 17
-
Kudlacz E, Conklyn M, Andresen C, Whitney-Pickett C, Changelian P. The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia. Eur J Pharmacol. 2008 Mar 17;582(1-3):154-161
-
(2008)
Eur J Pharmacol
, vol.582
, Issue.1-3
-
-
Kudlacz, E.1
Conklyn, M.2
Andresen, C.3
Whitney-Pickett, C.4
Changelian, P.5
-
81
-
-
10644234866
-
A rho kinase inhibitor, Y-27632 inhibits pulmonary eosinophiUa, broncho-constriction and airways hyperresponsiveness in allergic mice
-
Henry PJ, Mann TS, Goldie RG. A rho kinase inhibitor, Y-27632 inhibits pulmonary eosinophiUa, broncho-constriction and airways hyperresponsiveness in allergic mice. Pulm Pharmacol Ther. 2005;18(1):67-74.
-
(2005)
Pulm Pharmacol Ther
, vol.18
, Issue.1
-
-
Henry, P.J.1
Mann, T.S.2
Goldie, R.G.3
-
82
-
-
33749433631
-
Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction
-
DOI 10.1186/1465-9921-7-121
-
82. Schaafsma D, Bos IS, Zuidhof AB, Zaagsma J, Meurs H. Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction. Respir Res. 2006;7:121. (Pubitemid 44509624)
-
(2006)
Respiratory Research
, vol.7
-
-
Schaafsma, D.1
Bos, I.S.T.2
Zuidhof, A.B.3
Zaagsma, J.4
Meurs, H.5
-
83
-
-
49049090820
-
The inhaled Rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation
-
Jul
-
Schaafsma D, Bos IS, Zuidhof AB, Zaagsma J, Meurs H. The inhaled Rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation. Am J Physiol Lung CeU MoI Physiol. 2008 Jul;295(1):L214-9.
-
(2008)
Am J Physiol Lung CeU MoI Physiol
, vol.295
, Issue.1
-
-
Schaafsma, D.1
Bos, I.S.2
Zuidhof, A.B.3
Zaagsma, J.4
Meurs, H.5
-
84
-
-
34047227571
-
Effects of Rho-kinase inactivation on eosinophilia and hyper-reactivity in murine airways by allergen challenges
-
Apr
-
Taki F, Kume H, Kobayashi T, Ohta H, Aratake H, Shimokata K. Effects of Rho-kinase inactivation on eosinophilia and hyper-reactivity in murine airways by allergen challenges. Clin Exp Allergy. 2007 Apr;37(4):599-607.
-
(2007)
Clin Exp Allergy
, vol.37
, Issue.4
-
-
Taki, F.1
Kume, H.2
Kobayashi, T.3
Ohta, H.4
Aratake, H.5
Shimokata, K.6
-
85
-
-
0036344340
-
Uncovering new complexities in mast cell signaling
-
Aug
-
Nadler MJ, Kinet JP. Uncovering new complexities in mast cell signaling. Nat Immunol. 2002 Aug;3(8):707-708
-
(2002)
Nat Immunol
, vol.3
, Issue.8
-
-
Nadler, M.J.1
Kinet, J.P.2
-
86
-
-
61849130484
-
The tyrosine kinase network regulating mast cell activation
-
Mar
-
Gilfillan AM, Rivera J. The tyrosine kinase network regulating mast cell activation. Immunol Rev. 2009 Mar;228(1):149-169
-
(2009)
Immunol Rev
, vol.228
, Issue.1
-
-
Gilfillan, A.M.1
Rivera, J.2
-
87
-
-
1842414894
-
Src family-selective tyrosine kinase inhibitor, PP1, inhibits both FcεRI- And Thy-1-mediated activation of rat basophilic leukemia cells
-
DOI 10.1002/eji.1830270810
-
87. Amoui M, Draber P, Draberova L. Src family- selective tyrosine kinase inhibitor, PPl, inhibits both FcepsilonRI- and Thy-1-mediated activation of rat basophilic leukemia cells. Eur J Immunol. 1997 Aug;27(8):1881-1886 (Pubitemid 27346001)
-
(1997)
European Journal of Immunology
, vol.27
, Issue.8
-
-
Amoui, M.1
Draber, P.2
Draberova, L.3
-
88
-
-
61849152775
-
Multiple roles of Lyn kinase in myeloid cell signaling and function
-
Mar
-
Scapini P, Pereira S, Zhang H, Lowell CA. Multiple roles of Lyn kinase in myeloid cell signaling and function. Immunol Rev. 2009 Mar;228(1):23-40.
-
(2009)
Immunol Rev
, vol.228
, Issue.1
-
-
Scapini, P.1
Pereira, S.2
Zhang, H.3
Lowell, C.A.4
-
89
-
-
0036347746
-
Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
-
Aug
-
Parravicini V, Gadina M, Kovarova M, Odom S, Gonzalez-Espinosa C, Furumoto Y, Saitoh S, Samelson LE, O'Shea JJ, Rivera J. Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation. Nat Immunol. 2002 Aug;3(8):741-748
-
(2002)
Nat Immunol
, vol.3
, Issue.8
-
-
Parravicini, V.1
Gadina, M.2
Kovarova, M.3
Odom, S.4
Gonzalez-Espinosa, C.5
Furumoto, Y.6
Saitoh, S.7
Samelson, L.E.8
O'Shea, J.J.9
Rivera, J.10
-
90
-
-
2342460325
-
PI 3-kinase inhibition: A therapeutic target for respiratory disease
-
Apr
-
Finan PM, Thomas MJ. PI 3-kinase inhibition: a therapeutic target for respiratory disease. Biochem Soc Trans. 2004 Apr;32(Pt 2):378-382
-
(2004)
Biochem Soc Trans
, vol.32
, Issue.PART 2
-
-
Finan, P.M.1
Thomas, M.J.2
-
91
-
-
0030472724
-
Critical role for the tyrosine kinase Syk in signaling through the high affinity IgE receptor of mast cells
-
Dec 19
-
Costello PS, Turner M, Walters AE, Cunningham CN, Bauer PH, Downward J, Tybulewicz VL. Critical role for the tyrosine kinase Syk in signaling through the high affinity IgE receptor of mast cells. Oncogene. 1996 Dec 19;13(12):2595-2605
-
(1996)
Oncogene
, vol.13
, Issue.12
-
-
Costello, P.S.1
Turner, M.2
Walters, A.E.3
Cunningham, C.N.4
Bauer, P.H.5
Downward, J.6
Tybulewicz, V.L.7
-
92
-
-
0037020143
-
Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells
-
Oct 4
-
Paolini R, Molfetta R, Beitz LO, Zhang J, Scharenberg AM, Piccoli M, Frati L, Siraganian R, Santoni A. Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells. J Biol Chem. 2002 Oct 4;277(40):36940-36947
-
(2002)
J Biol Chem
, vol.277
, Issue.40
-
-
Paolini, R.1
Molfetta, R.2
Beitz, L.O.3
Zhang, J.4
Scharenberg, A.M.5
Piccoli, M.6
Frati, L.7
Siraganian, R.8
Santoni, A.9
-
93
-
-
30344435280
-
Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness
-
DOI 10.1164/rccm.200503-361OC
-
93. Matsubara S, Li G, Takeda K, Loader JE, Pine P, Masuda ES, Miyahara N, Miyahara S, Lucas JJ, Dakhama A, Gelfand EW Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyper-responsiveness. Am J Respir Crit Care Med. 2006 Jan 1;173(1):56-63. (Pubitemid 43069788)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.173
, Issue.1
-
-
Matsubara, S.1
Li, G.2
Takeda, K.3
Loader, J.E.4
Pine, P.5
Masuda, E.S.6
Miyahara, N.7
Miyahara, S.8
Lucas, J.J.9
Dakhama, A.10
Gelfand, E.W.11
-
94
-
-
9644287858
-
Loss of syk kinase during IgE-mediated stimulation of human basophils
-
DOI 10.1016/j.jaci.2004.08.037, PII S0091674904022924
-
94. Macglashan D, Miura K. Loss of syk kinase during IgE-mediated stimulation of human basophils. J Allergy Clin Immunol. 2004 Dec;114(6):1317-1324 (Pubitemid 39575884)
-
(2004)
Journal of Allergy and Clinical Immunology
, vol.114
, Issue.6
-
-
MacGlashan Jr., D.1
Miura, K.2
-
95
-
-
16244397342
-
An intranasal Syk-kinase inhibitor (Rl 12) improves the symptoms of seasonal aEergic rhinitis in a park environment
-
Apr
-
Meltzer EO, Berkowitz RB, Grossbard EB. An intranasal Syk-kinase inhibitor (Rl 12) improves the symptoms of seasonal aEergic rhinitis in a park environment. J Allergy Clin Immunol. 2005 Apr;115(4):791-796
-
(2005)
J Allergy Clin Immunol
, vol.115
, Issue.4
-
-
Meltzer, E.O.1
Berkowitz, R.B.2
Grossbard, E.B.3
-
96
-
-
0034176940
-
Aerosolized Syk antisense suppresses Syk expression, mediator release from macrophages, and pulmonary inflammation
-
96. Stenton GR, Kim MK, Nohara O, Chen CF, Hirji N, Wills FL, Gilchrist M, Hwang PH, Park JG, Finlay W, Jones RL, Befus AD, Schreiber AD. Aerosolized Syk antisense suppresses Syk expression, mediator release from macrophages, and pulmonary inflammation. J Immunol. 2000 Apr 1;164(7):3790-3797 (Pubitemid 30169836)
-
(2000)
Journal of Immunology
, vol.164
, Issue.7
-
-
Stenton, G.R.1
Kim, M.-K.2
Nohara, O.3
Chen, C.-F.4
Hirji, N.5
Wills, F.L.6
Gilchrist, M.7
Hwang, P.-H.8
Park, J.-G.9
Finlay, W.10
Jones, R.L.11
Befus, A.D.12
Schreiber, A.D.13
-
97
-
-
0037100457
-
Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase
-
97. Stenton GR, Ulanova M, Dery RE, Merani S, Kim MK, Gilchrist M, Puttagunta L, Musat-Marcu S, James D, Schreiber AD, Befus AD. Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase. J Immunol. 2002 Jul 15;169(2):1028-1036 (Pubitemid 34753463)
-
(2002)
Journal of Immunology
, vol.169
, Issue.2
-
-
Stenton, G.R.1
Ulanova, M.2
Dery, R.E.3
Merani, S.4
Kim, M.-K.5
Gilchrist, M.6
Puttagunta, L.7
Musat-Marcu, S.8
James, D.9
Schreiber, A.D.10
Befus, A.D.11
-
98
-
-
7244232917
-
Essential role for the p110delta phosphoinositide 3-kinase in the allergic response
-
Oct 21
-
Ali K, Bilancio A, Thomas M, Pearce W, Gilfillan AM, Tkaczyk C, Kuehn N, Gray A, Giddings J, Peskett E, Fox R, Bruce I, Walker C, Sawyer C, Okkenhaug K, Finan P, Vanhaesebroeck B. Essential role for the p110delta phosphoinositide 3-kinase in the allergic response. Nature. 2004 Oct 21;431(7011):1007-1011
-
(2004)
Nature
, vol.431
, Issue.7011
-
-
Ali, K.1
Bilancio, A.2
Thomas, M.3
Pearce, W.4
Gilfillan, A.M.5
Tkaczyk, C.6
Kuehn, N.7
Gray, A.8
Giddings, J.9
Peskett, E.10
Fox, R.11
Bruce, I.12
Walker, C.13
Sawyer, C.14
Okkenhaug, K.15
Finan, P.16
Vanhaesebroeck, B.17
-
99
-
-
42149091691
-
Isoform-specific functions of phosphoinositide 3-kinases: P110 delta but not p1 gamma promotes optimal allergic responses in vivo
-
Feb 15
-
Ali K, Camps M, Pearce WP, Ji H, Ruckle T, Kuehn N, Pasquali C, Chabert C, Rommel C, Vanhaesebroeck B. Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p1 gamma promotes optimal allergic responses in vivo. J Immunol. 2008 Feb 15;180(4):2538-2544
-
(2008)
J Immunol
, vol.180
, Issue.4
-
-
Ali, K.1
Camps, M.2
Pearce, W.P.3
Ji, H.4
Ruckle, T.5
Kuehn, N.6
Pasquali, C.7
Chabert, C.8
Rommel, C.9
Vanhaesebroeck, B.10
-
100
-
-
2942737134
-
Rac and protein kinase C-delta regulate ERKs and cytosolic phospholipase A2 in FcepsilonRI signaling to cysteinyl leukotriene synthesis in mast cells
-
Jul 1
-
Cho SH, You HJ, Woo CH, Yoo YJ, Kim JH. Rac and protein kinase C-delta regulate ERKs and cytosolic phospholipase A2 in FcepsilonRI signaling to cysteinyl leukotriene synthesis in mast cells. J Immunol. 2004 Jul 1;173(1):624-631
-
(2004)
J Immunol
, vol.173
, Issue.1
-
-
Cho, S.H.1
You, H.J.2
Woo, C.H.3
Yoo, Y.J.4
Kim, J.H.5
-
101
-
-
0036200415
-
Phosphoinositide 3-kinase gamma is an essential amphfier of mast cell function
-
Mar
-
Laffargue M, Calvez R, Finan P, Trifilieff A, Barbier M, Altruda F, Hirsch E, Wymann MP. Phosphoinositide 3-kinase gamma is an essential amphfier of mast cell function. Immunity. 2002 Mar;16(3):441-451
-
(2002)
Immunity.
, vol.16
, Issue.3
-
-
Laffargue, M.1
Calvez, R.2
Finan, P.3
Trifilieff, A.4
Barbier, M.5
Altruda, F.6
Hirsch, E.7
Wymann, M.P.8
-
102
-
-
0035209940
-
Regulation of the very late antigen -4- Mediated adhesive activity of normal and nonreleaser basophils: Roles for Src, Syk, and phosphatidylinositol 3-kinase
-
102. Andrews RP, Kepley CL, Youssef L, Wilson B S, Oliver JM. Regulation of the very late antigen-4-mediated adhesive activity of normal and nonreleaser basophils: roles for Src, Syk, and phosphatidylinositol 3-kinase. J Leukoc Biol. 2001 Nov;70(5):776-782 (Pubitemid 33127012)
-
(2001)
Journal of Leukocyte Biology
, vol.70
, Issue.5
-
-
Andrews, R.P.1
Kepley, C.L.2
Youssef, L.3
Wilson, B.S.4
Oliver, J.M.5
-
103
-
-
0030051454
-
The phosphatidylinositol 3-kinase inhibitor wortmannin blocks mast cell exocytosis but not IL-6 production
-
Mar 1
-
Marquardt DL, Alongi JL, Walker LL.The phosphatidylinositol 3-kinase inhibitor wortmannin blocks mast cell exocytosis but not IL-6 production. J Immunol. 1996 Mar 1;156(5):1942-1945
-
(1996)
J Immunol
, vol.156
, Issue.5
-
-
Marquardt, D.L.1
Alongi, J.L.2
Walker, L.L.3
-
104
-
-
0033712415
-
Treatment of allergic asthma by targeting Janus kinase 3-dependent leukotriene synthesis in mast cells with 4-(3',5'-dibromo-4'-hydroxyphenyl) amino-6,7-dimethoxyquinazoline (WHI-P97)
-
104. Malaviya R, Chen CL, Navara C, Malaviya R, Liu XP, Keenan M, Waurzyniak B, Uckun FM.Treatment of allergic asthma by targeting janus kinase 3-dependent leukotriene synthesis in mast cells with 4-(3′, 5′-dibromo-4′-hydroxyphenyl)amino-6,7-dimethoxy-quinazoline (WHI-P97). J Pharmacol Exp Ther. 2000 Dec;295(3):912-926 (Pubitemid 30951548)
-
(2000)
Journal of Pharmacology and Experimental Therapeutics
, vol.295
, Issue.3
-
-
Malaviya, R.1
Chen, C.-L.2
Navara, C.3
Malaviya, R.4
Liu, X.-P.5
Keenan, M.6
Waurzyniak, B.7
Uckun, F.M.8
-
105
-
-
0037392883
-
Positive and negative regulation of T-cell activation through kinases and phosphatases
-
Apr 1
-
Mustelin T, Tasken K. Positive and negative regulation of T-cell activation through kinases and phosphatases. Biochem J. 2003 Apr 1;371(Pt 1):15-27.
-
(2003)
Biochem J
, vol.371
, Issue.PART 1
-
-
Mustelin, T.1
Tasken, K.2
-
107
-
-
3342918498
-
The p38 MAP kinase pathway as a therapeutic target in inflammatory disease
-
Aug
-
Saklatvala J. The p38 MAP kinase pathway as a therapeutic target in inflammatory disease. Curr Opin Pharmacol. 2004 Aug;4(4):372-377
-
(2004)
Curr Opin Pharmacol
, vol.4
, Issue.4
-
-
Saklatvala, J.1
-
108
-
-
0034653460
-
Eotaxin induces degranulation and Chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases
-
Mar 15
-
Kampen GT, Stafford S, Adachi T, Jinquan T, Quan S, Grant JA, Skov PS, Poulsen LK, Alam R. Eotaxin induces degranulation and Chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases. Blood. 2000 Mar 15;95(6):1911-1917
-
(2000)
Blood
, vol.95
, Issue.6
-
-
Kampen, G.T.1
Stafford, S.2
Adachi, T.3
Jinquan, T.4
Quan, S.5
Grant, J.A.6
Skov, P.S.7
Poulsen, L.K.8
Alam, R.9
-
109
-
-
18544406054
-
SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence
-
109. Underwood DC, Osborn RR, Kötzer CJ, Adams JL, Lee JC, Webb EF, Carpenter DC, Bochnowicz S, Thomas HC, Hay DW, Griswold DE. SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence. J Pharmacol Exp Ther. 2000 Apr;293(1):281-288 (Pubitemid 30180950)
-
(2000)
Journal of Pharmacology and Experimental Therapeutics
, vol.293
, Issue.1
-
-
Underwood, D.C.1
Osborn, R.R.2
Kotzer, C.J.3
Adams, J.L.4
Lee, J.C.5
Webb, E.F.6
Carpenter, D.C.7
Bochnowicz, S.8
Thomas, H.C.9
Hay, D.W.P.10
Griswold, D.E.11
-
110
-
-
0033778848
-
Effect of the p38 kinase inhibitor, SB 203580, on allergic airway inflammation in the rat
-
110. Escott KJ, Belvisi MG, Birrell MA, Webber SE, Foster ML, Sargent CA. Effect of the p38 kinase inhibitor, SB 203580, on allergic airway inflammation in the rat. Br J Pharmacol. 2000 Sep;131(2):173-176 (Pubitemid 30768113)
-
(2000)
British Journal of Pharmacology
, vol.131
, Issue.2
-
-
Escott, K.J.1
Belvisi, M.G.2
Birrell, M.A.3
Webber, S.E.4
Foster, M.L.5
Sargent, C.A.6
-
111
-
-
0032763790
-
SB 203580, an inhibitor of p38 mitogen-activated protein kinase, enhances constitutive apoptosis of cytokine-deprived human eosinophils
-
111. Kankaanranta H, De Souza PM, Barnes PJ, Salmon M, Giembycz MA, Lindsay MA. SB 203580, an inhibitor of p38 mitogen-activated protein kinase, enhances constitutive apoptosis of cytokine-deprived human eosinophils. J Pharmacol Exp Ther. 1999 Aug;290(2):621-628 (Pubitemid 29344554)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.290
, Issue.2
-
-
Kankaanranta, H.1
De Souza, P.M.2
Barnes, P.J.3
Salmon, M.4
Giembycz, M.A.5
Lindsay, M.A.6
-
112
-
-
34447507590
-
C-Jun N-terminal kinase mediates constitutive human eosinophil apoptosis
-
DOI 10.1016/j.pupt.2006.06.004, PII S1094553906000691
-
112. Hasala H, Zhang X, Saarelainen S, Moilanen E, Kankaanranta H. c-Jun N-terminal kinase mediates constitutive human eosinophil apoptosis. Pulm Pharmacol Ther. 2007;20(5):580-587 (Pubitemid 47077650)
-
(2007)
Pulmonary Pharmacology and Therapeutics
, vol.20
, Issue.5
-
-
Hasala, H.1
Zhang, X.2
Saarelainen, S.3
Moilanen, E.4
Kankaanranta, H.5
-
113
-
-
0030776790
-
Relationship between il-4 and il-5 mrna expression and disease severity in atopic asthma
-
113. Humbert M, Corrigan CJ, Kimmitt P, Till SJ, Kay AB, Durham SR. Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma. Am J Respir Crit Care Med. 1997 Sep;156(3 Pt 1):704-708 (Pubitemid 27396404)
-
(1997)
American Journal of Respiratory and Critical Care Medicine
, vol.156
-
-
Humbert, M.1
Corrigan, C.J.2
Kimmitt, P.3
Till, S.J.4
Kay, A.B.5
Durham, S.R.6
-
114
-
-
0032711893
-
P38 mitogen-activated protein kinase regulates human T cell IL-5 synthesis
-
114. Mori A, Kaminuma O, Miyazawa K, Ogawa K, Okudaira H, Akiyama K. p38 mitogen-activated protein kinase regulates human T cell IL-5 synthesis. J Immunol. 1999 Nov 1;163(9):4763-4771 (Pubitemid 29501238)
-
(1999)
Journal of Immunology
, vol.163
, Issue.9
-
-
Mori, A.1
Kaminuma, O.2
Miyazawa, K.3
Ogawa, K.4
Okudaira, H.5
Akiyama, K.6
-
115
-
-
0035051557
-
Selective regulation of T cell IL-5 synthesis by OM-01, JTE-711 and p38 MAP kinase inhibitor: Independent control of Th2 cytokines, IL-4 and IL-5
-
Jan
-
Mori A, Okudaira H, Kobayashi N, Akiyama K. Selective regulation of T cell IL-5 synthesis by OM-01, JTE-711 and p38 MAP kinase inhibitor: independent control of Th2 cytokines, IL-4 and IL-5. Int Arch Allergy Immunol. 2001 Jan;124(1-3):172-175
-
(2001)
Int Arch Allergy Immunol
, vol.124
, Issue.1-3
-
-
Mori, A.1
Okudaira, H.2
Kobayashi, N.3
Akiyama, K.4
-
116
-
-
0037111477
-
In vivo role of p38 mitogen-activated protein kinase in mediating the anti-inflammatory effects of CpG oligodeoxynucleotide in murine asthma
-
Nov 15
-
Choudhury BK, Wild JS, Alam R, Klinman DM, Boldogh I, Dharajiya N, Mileski WJ, Sur S. In vivo role of p38 mitogen-activated protein kinase in mediating the anti-inflammatory effects of CpG oligodeoxynucleotide in murine asthma. J Immunol. 2002 Nov 15;169(10):5955-5961
-
(2002)
J Immunol
, vol.169
, Issue.10
-
-
Choudhury, B.K.1
Wild, J.S.2
Alam, R.3
Klinman, D.M.4
Boldogh, I.5
Dharajiya, N.6
Mileski, W.J.7
Sur, S.8
-
117
-
-
0742324860
-
TLR signaling pathways
-
Feb
-
Takeda K, Akira S. TLR signaling pathways. Semin Immunol. 2004 Feb;16(1):3-9.
-
(2004)
Semin Immunol
, vol.16
, Issue.1
-
-
Takeda, K.1
Akira, S.2
-
118
-
-
0033179690
-
Activation of mitogen-activated protein kinase regulates eotaxin- Induced eosinophil migration
-
118. Boehme SA, Sullivan SK, Crowe PD, Santos M, Conlon PJ, Sriramarao P, Bacon KB. Activation of mitogen-activated protein kinase regulates eotaxin-induced eosinophil migration. J Immunol. 1999 Aug 1;163(3):1611-1618 (Pubitemid 29352786)
-
(1999)
Journal of Immunology
, vol.163
, Issue.3
-
-
Boehme, S.A.1
Sullivan, S.K.2
Crowe, P.D.3
Santos, M.4
Conlon, P.J.5
Sriramarao, P.6
Bacon, K.B.7
-
119
-
-
2442712697
-
Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model
-
119. Duan W, Chan JH, Wong CH, Leung BP, Wong WS. Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model. J Immunol. 2004 Jun 1;172(11):7053-7059 (Pubitemid 38669147)
-
(2004)
Journal of Immunology
, vol.172
, Issue.11
-
-
Duan, W.1
Chan, J.H.P.2
Wong, C.H.3
Leung, B.P.4
Wong, W.S.F.5
-
120
-
-
3042557933
-
Inhibitor of p42/44 mitogen-activated protein kinase, but not p38 MAPK, attenuated antigen challenge of guinea pig airways in vitro
-
Aug
-
Chue SC, Seow CJ, Duan W, Yeo KS, Koh AH, Wong WS. Inhibitor of p42/44 mitogen-activated protein kinase, but not p38 MAPK, attenuated antigen challenge of guinea pig airways in vitro. Int Immunopharmacol. 2004 Aug;4(8):1089-1098
-
(2004)
Int Immunopharmacol
, vol.4
, Issue.8
-
-
Chue, S.C.1
Seow, C.J.2
Duan, W.3
Yeo, K.S.4
Koh, A.H.5
Wong, W.S.6
-
121
-
-
0032509479
-
Defective T cell differentiation in the absence of Jnk1
-
Dec 11
-
Dong C, Yang DD, Wysk M, Whitmarsh AJ, Davis RJ, Flavell RA. Defective T cell differentiation in the absence of Jnk1. Science. 1998 Dec 11;282(5396):2092-2095
-
(1998)
Science
, vol.282
, Issue.5396
-
-
Dong, C.1
Yang, D.D.2
Wysk, M.3
Whitmarsh, A.J.4
Davis, R.J.5
Flavell, R.A.6
-
122
-
-
0347949530
-
Allergen-induced inflammation and airway epithelial and smooth muscle cell proliferation: Role of Jun N-terminal kinase
-
DOI 10.1038/sj.bjp.0705569
-
122. Eynott PR, Nath P, Leung SY, Adcock IM, Bennett BL, Chung KF. Allergen-induced inflammation and airway epithelial and smooth muscle cell proliferation: role of Jun N-terminal kinase. Br J Pharmacol. 2003 Dec;140(8):1373-1380 (Pubitemid 38067844)
-
(2003)
British Journal of Pharmacology
, vol.140
, Issue.8
-
-
Eynott, P.R.1
Nath, P.2
Leung, S.-Y.3
Adcock, I.M.4
Bennett, B.L.5
Chung, K.F.6
-
123
-
-
14944386613
-
2-terminal kinase in allergic airway inflammation and remodelling: Effects of SP600125
-
DOI 10.1016/j.ejphar.2004.11.040, PII S001429990401266X
-
123. Nath P, Eynott P, Leung SY, Adcock IM, Bennett BL, Chung KF. Potential role of c-Jun NH2-terminal kinase in allergic airway inflammation and remodel-Eur effects of SP600125. Eur J Pharmacol. 2005 Jan 4;506(3):273-283 (Pubitemid 41071400)
-
(2005)
European Journal of Pharmacology
, vol.506
, Issue.3
-
-
Nath, P.1
Eynott, P.2
Leung, S.-Y.3
Adcock, I.M.4
Bennett, B.L.5
Kian, F.C.6
-
124
-
-
3042752921
-
Effect of an inhibitor of Jun N-terminal protein kinase, SP600125, in single allergen challenge in sensitized rats
-
Jul
-
Eynott PR, Xu L, Bennett BL, Noble A, Leung SY, Nath P, Groneberg DA, Adcock IM, Chung KF. Effect of an inhibitor of Jun N-terminal protein kinase, SP600125, in single allergen challenge in sensitized rats. Immunology. 2004 Jul;112(3):446-453
-
(2004)
Immunology
, vol.112
, Issue.3
-
-
Eynott, P.R.1
Xu, L.2
Bennett, B.L.3
Noble, A.4
Leung, S.Y.5
Nath, P.6
Groneberg, D.A.7
Adcock, I.M.8
Chung, K.F.9
-
125
-
-
23144461838
-
Inflammatory pathway analysis using a high content screening platform
-
Jun
-
Bertelsen M, Sanfridson A. Inflammatory pathway analysis using a high content screening platform. Assay Drug Dev Technol. 2005 Jun;3(3):261-271
-
(2005)
Assay Drug Dev Technol
, vol.3
, Issue.3
-
-
Bertelsen, M.1
Sanfridson, A.2
-
126
-
-
25444511529
-
Inhibitors of mitogen-activated protein kinases differentially regulate costimulated T cell cytokine production and mouse airway eosinophilia
-
Apr 15
-
Chialda L, Zhang M, Brune K, Pahl A. Inhibitors of mitogen-activated protein kinases differentially regulate costimulated T cell cytokine production and mouse airway eosinophilia. Respir Res. 2005 Apr 15;6(1):36.
-
(2005)
Respir Res
, vol.6
, Issue.1
-
-
Chialda, L.1
Zhang, M.2
Brune, K.3
Pahl, A.4
-
127
-
-
0037662016
-
Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5
-
DOI 10.1067/mai.2003.1587
-
127. Zhang X, Msc, Moilanen E, Lahti A, Hamalainen M, Giembycz MA, Barnes PJ, Lindsay MA, Kankaanranta H. Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5. J Allergy Clin Immunol. 2003 Jul;112(1):93-101. (Pubitemid 36819813)
-
(2003)
Journal of Allergy and Clinical Immunology
, vol.112
, Issue.1
-
-
Zhang, X.1
Moilanen, E.2
Lahti, A.3
Hamalainen, M.4
Giembycz, M.A.5
Barnes, P.J.6
Lindsay, M.A.7
Kankaanranta, H.8
-
128
-
-
1342292522
-
Phosphoinositide 3-kinase: Diverse roles in immune cell activation
-
DOI 10.1146/annurev.immunol.22.012703.104721
-
128. Deane JA, Fruman DA. Phosphoinositide 3-kinase: diverse roles in immune cell activation. Annu Rev Immunol. 2004;22:563-598 (Pubitemid 38680434)
-
(2004)
Annual Review of Immunology
, vol.22
-
-
Deane, J.A.1
Fruman, D.A.2
-
129
-
-
0035907389
-
2+ influx by enhancing inositol 1,4,5-trisphosphate production
-
May 18
-
2+ influx by enhancing inositol 1,4,5-trisphosphate production. J Biol Chem. 2001 May 18;276(20):17213-17220
-
(2001)
J Biol Chem
, vol.276
, Issue.20
-
-
Smith, A.J.1
Surviladze, Z.2
Gaudet, E.A.3
Backer, J.M.4
Mitchell, C.A.5
-
130
-
-
0038823621
-
Distinct phosphoinositide 3-kinases mediate mast cell degranulation in response to G-protein-coupled versus Fcepsilon RI receptors
-
Apr 4
-
Windmiller DA, Backer JM. Distinct phosphoinositide 3-kinases mediate mast cell degranulation in response to G-protein-coupled versus Fcepsilon RI receptors. J Biol Chem. 2003 Apr 4;278(14):11874-11878
-
(2003)
J Biol Chem
, vol.278
, Issue.14
-
-
Windmiller, D.A.1
Backer, J.M.2
-
131
-
-
0037387875
-
The phosphatidylinositol 3-kinase inhibitor LY294002 potently blocks K(V) currents via a direct mechanism
-
Apr
-
El-Kholy W, Macdonald PE, Lin JH, Wang J, Fox JM, Light PE, Wang Q, Tsushima RG, Wheeler MB. The phosphatidylinositol 3-kinase inhibitor LY294002 potently blocks K(V) currents via a direct mechanism. FASEB J. 2003 Apr;17(6):720-722
-
(2003)
FASEB J
, vol.17
, Issue.6
-
-
El-Kholy, W.1
Macdonald, P.E.2
Lin, J.H.3
Wang, J.4
Fox, J.M.5
Light, P.E.6
Wang, Q.7
Tsushima, R.G.8
Wheeler, M.B.9
-
132
-
-
0029996127
-
Calcium mobilization via sphingosine kinase in signaling by the Fcepsilon RI antigen receptor
-
Apr 18
-
Choi OH, Kim JH, Kinet JP. Calcium mobilization via sphingosine kinase in signaling by the Fcepsilon RI antigen receptor. Nature. 1996 Apr 18;380(6575):634-636
-
(1996)
Nature
, vol.380
, Issue.6575
-
-
Choi, O.H.1
Kim, J.H.2
Kinet, J.P.3
-
133
-
-
0037052338
-
2+ signals triggered by different phosphohpid pathways in antigen stimulation of human mast cells
-
May 10
-
2+ signals triggered by different phosphohpid pathways in antigen stimulation of human mast cells. J Biol Chem. 2002 May 10;277(19):17255-17262
-
(2002)
J Biol Chem
, vol.277
, Issue.19
-
-
Melendez, A.J.1
Khaw, A.K.2
-
134
-
-
44849137343
-
The role of sphingosine kinase in a murine model of allergic asthma
-
Mar 15
-
Lai WQ, Goh HH, Bao Z, Wong WS, Melendez AJ, Leung BP. The role of sphingosine kinase in a murine model of allergic asthma. J Immunol. 2008 Mar 15;180(6):4323-4329
-
(2008)
J Immunol
, vol.180
, Issue.6
-
-
Lai, W.Q.1
Goh, H.H.2
Bao, Z.3
Wong, W.S.4
Melendez, A.J.5
Leung, B.P.6
-
135
-
-
48949119356
-
Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model
-
Jun
-
Nishiuma T, Nishimura Y, Okada T, Kuramoto E, Kotani Y, Jahangeer S, Nakamura S. Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model. Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1085-L1093.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
, Issue.6
-
-
Nishiuma, T.1
Nishimura, Y.2
Okada, T.3
Kuramoto, E.4
Kotani, Y.5
Jahangeer, S.6
Nakamura, S.7
-
136
-
-
3342953519
-
Human eosinophil Chemotaxis and selective in vivo recruitment by sphingosine 1-phosphate
-
Jul 27
-
Roviezzo F, Del GF, Abbate G, Bucci M, D'Agostino B, Antunes E, De DG, Parente L, Rossi F, Cirino G, De PR. Human eosinophil Chemotaxis and selective in vivo recruitment by sphingosine 1-phosphate. Proc Natl Acad Sci USA. 2004 Jul 27;101(30):11170-11175
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.30
-
-
Roviezzo, F.1
Abbate G, D.G.F.2
Bucci, M.3
D'Agostino, B.4
Antunes, E.5
De, D.G.6
Parente, L.7
Rossi, F.8
Cirino, G.9
De, P.R.10
-
137
-
-
0033548157
-
Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase
-
Feb 12
-
Alemany R, Meyer zu HD, van Koppen CJ, Jakobs KH. Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase. J Biol Chem. 1999 Feb 12;274(7):3994-3999
-
(1999)
J Biol Chem
, vol.274
, Issue.7
-
-
Alemany, R.1
Meyer Zu, H.D.2
Van Koppen, C.J.3
Jakobs, K.H.4
-
138
-
-
0029027589
-
Sphingosine-1-phosphate inhibits PDGF-induced Chemotaxis of human arterial smooth muscle cells: Spatial and temporal modulation of PDGF chemotactic signal transduction
-
Jul
-
Bomfeldt KE, Graves LM, Raines EW, Igarashi Y, Wayman G, Yamamura S, Yatomi Y, Sidhu JS, Krebs EG, Hakomori S,. Sphingosine-1-phosphate inhibits PDGF-induced Chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction. J Cell Biol. 1995 Jul;130(1):193-206.
-
(1995)
J Cell Biol
, vol.130
, Issue.1
-
-
Bomfeldt, K.E.1
Graves, L.M.2
Raines, E.W.3
Igarashi, Y.4
Wayman, G.5
Yamamura, S.6
Yatomi, Y.7
Sidhu, J.S.8
Krebs, E.G.9
Hakomori, S.10
-
139
-
-
7244250149
-
Anaphylatoxin signaling in human neutroprdls. A key role for sphingosine kinase
-
Oct 22
-
Ibrahim FB, Pang SJ, Melendez AJ. Anaphylatoxin signaling in human neutroprdls. A key role for sphingosine kinase. J Biol Chem. 2004 Oct 22;279(43): 44802-44811
-
(2004)
J Biol Chem
, vol.279
, Issue.43
-
-
Ibrahim, F.B.1
Pang, S.J.2
Melendez, A.J.3
-
140
-
-
3242791547
-
2+ signals, enzyme release, cytokine production, and Chemotaxis
-
Aug l
-
2+ signals, enzyme release, cytokine production, and Chemotaxis. J Immunol. 2004 Aug l;173(3):1596-1603
-
(2004)
J Immunol
, vol.173
, Issue.3
-
-
Melendez, A.J.1
Ibrahim, F.B.2
-
141
-
-
0027371722
-
Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
-
Oct 7
-
Olivera A, Spiegel S. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature. 1993 Oct 7;365(6446):557-560
-
(1993)
Nature
, vol.365
, Issue.6446
-
-
Olivera, A.1
Spiegel, S.2
-
142
-
-
33744929865
-
Sphingosine kinase 1 regulates pro-inflammatory responses triggered by TNFα in primary human monocytes
-
DOI 10.1002/jcp.20646
-
142. Zhi L, Leung BP, Melendez AJ. Sphingosine kinase 1 regulates pro-inflammatory responses triggered by TNFalpha in primary human monocytes. J Cell Physiol. 2006 Jul;208(1):109-115 (Pubitemid 43848994)
-
(2006)
Journal of Cellular Physiology
, vol.208
, Issue.1
-
-
Zhi, L.1
Leung, B.P.2
Melendez, A.J.3
-
143
-
-
0032754544
-
Effects of inhibitors of the tyrosine kinase signaling cascade on an in vitro model of allergic airways
-
143. Wong WS, Tsang F, Li H, Ma B. Effects of inhibitors of the tyrosine kinase signaling cascade on an in vitro model of allergic airways. Asian Pac J Allergy Immunol. 1999 Sep;17(3):229-237 (Pubitemid 29512105)
-
(1999)
Asian Pacific Journal of Allergy and Immunology
, vol.17
, Issue.3
-
-
Wong, W.S.F.1
Tsang, F.2
Li, H.3
Ma, B.4
-
144
-
-
19944432162
-
Mitogen-activated protein kinases and asthma
-
Mar
-
Pelaia G, Cuda G, Vatrella A, Gallelli L, Caraglia M, Marra M, Abbruzzese A, Caputi M, Maselli R, Costanzo FS, Marsico SA. Mitogen-activated protein kinases and asthma. J Cell Physiol. 2005 Mar;202(3):642-653
-
(2005)
J Cell Physiol
, vol.202
, Issue.3
-
-
Pelaia, G.1
Cuda, G.2
Vatrella, A.3
Gallelli, L.4
Caraglia, M.5
Marra, M.6
Abbruzzese, A.7
Caputi, M.8
Maselli, R.9
Costanzo, F.S.10
Marsico, S.A.11
-
145
-
-
50249105938
-
Tailoring T-cell receptor signals by proximal negative feedback mechanisms
-
Sep
-
Acuto O, Di Bartolo V, Micheli F. Tailoring T-cell receptor signals by proximal negative feedback mechanisms. Nat Rev Immunol. 2008 Sep;8(9):699-712.
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.9
-
-
Acuto, O.1
Di Bartolo, V.2
Micheli, F.3
-
146
-
-
42649105767
-
Protein tyrosine phosphatases in autoimmunity
-
Vang T, Miletic AV, Arimura Y, Tautz L, Rickert RC, Mustelin T. Protein tyrosine phosphatases in autoimmunity. Annu Rev Immunol. 2008;26:29-55.
-
(2008)
Annu Rev Immunol
, vol.26
-
-
Vang, T.1
Miletic, A.V.2
Arimura, Y.3
Tautz, L.4
Rickert, R.C.5
Mustelin, T.6
-
147
-
-
33847176551
-
MAPK phosphatases-regulating the immune response
-
Mar
-
Liu Y, Shepherd EG, NeHn LD. MAPK phosphatases-regulating the immune response. Nat Rev Immunol. 2007 Mar;7(3):202-212
-
(2007)
Nat Rev Immunol
, vol.7
, Issue.3
-
-
Liu, Y.1
Shepherd, E.G.2
Nehn, L.D.3
-
148
-
-
34247881790
-
Nonreceptor protein-tyrosine phosphatases in immune cell signaling
-
DOI 10.1146/annurev.immunol.23.021704.115647
-
148. Pao LI, Badour K, Siminovitch KA, Neel BG. Nonreceptor protein-tyrosine phosphatases in immune cell signaling. Annu Rev Immunol. 2007;25:473-523. (Pubitemid 46697915)
-
(2007)
Annual Review of Immunology
, vol.25
-
-
Pao, L.I.1
Badour, K.2
Siminovitch, K.A.3
Neel, B.G.4
-
149
-
-
0027195626
-
Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene
-
Jun
-
Tsui HW, Siminovitch KA, de SL, Tsui FW. Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene. Nat Genet. 1993 Jun;4(2):124-129
-
(1993)
Nat Genet
, vol.4
, Issue.2
-
-
Tsui, H.W.1
Siminovitch, K.A.2
De, S.L.3
Tsui, F.W.4
-
150
-
-
0033794917
-
Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signahng
-
Aug
-
Zhang J, Somani AK, Siminovitch KA. Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signahng. Semin Immunol. 2000 Aug;12(4):361-378
-
(2000)
Semin Immunol
, vol.12
, Issue.4
-
-
Zhang, J.1
Somani, A.K.2
Siminovitch, K.A.3
-
151
-
-
40849136040
-
Protein tyrosine phosphatase inhibition induces anti-tumor activity: Evidence of Cdk2/p27 kipl and Cdk2/SHP-1 complex formation in human ovarian cancer cells
-
Apr 18
-
Caron D, Savard PE, Doillon CJ, Olivier M, Shink E, Lussier JG, Faure RL. Protein tyrosine phosphatase inhibition induces anti-tumor activity: evidence of Cdk2/p27 kipl and Cdk2/SHP-1 complex formation in human ovarian cancer cells. Cancer Lett. 2008 Apr 18;262(2):265-275
-
(2008)
Cancer Lett
, vol.262
, Issue.2
-
-
Caron, D.1
Savard, P.E.2
Doillon, C.J.3
Olivier, M.4
Shink, E.5
Lussier, J.G.6
Faure, R.L.7
-
152
-
-
0032577457
-
Modulation of interferon-γ/-induced macrophage activation by phosphotyrosine phosphatases inhibition: Effect on murine leishmaniasis progression
-
DOI 10.1074/jbc.273.22.13944
-
152. Olivier M, Romero-Gallo BJ, Matte C, Blanchette J, Posner BI, Tremblay MJ, Faure R. Modulation of interferon-gamma-induced macrophage activation by phosphotyrosine phosphatases inhibition. Effect on murine Leishmaniasis progression. J Biol Chem. 1998 May 29;273(22):13944-13949 (Pubitemid 28268449)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.22
-
-
Olivier, M.1
Romero-Gallo, B.-J.2
Matte, C.3
Blanchette, J.4
Posner, B.I.5
Tremblay, M.J.6
Faure, R.7
-
153
-
-
0033826015
-
Peroxovanadium-mediated protection against murine leishmaniasis: Role of the modulation of nitric oxide
-
Sep
-
Matte C, Marquis JF, Blanchette J, Gros P, Faure R, Posner BI, Olivier M. Peroxovanadium-mediated protection against murine leishmaniasis: role of the modulation of nitric oxide. Eur J Immunol. 2000 Sep;30(9):2555-2564
-
(2000)
Eur J Immunol
, vol.30
, Issue.9
-
-
Matte, C.1
Marquis, J.F.2
Blanchette, J.3
Gros, P.4
Faure, R.5
Posner, B.I.6
Olivier, M.7
-
154
-
-
63149148939
-
Protein tyrosine phosphatases regulate asthma development in a murine asthma model
-
Feb 1
-
Pouliot P, Camateros P, Radzioch D, Lambrecht BN, Olivier M. Protein tyrosine phosphatases regulate asthma development in a murine asthma model. J Immunol. 2009 Feb 1;182(3):1334-1340
-
(2009)
J Immunol
, vol.182
, Issue.3
-
-
Pouliot, P.1
Camateros, P.2
Radzioch, D.3
Lambrecht, B.N.4
Olivier, M.5
-
155
-
-
70449356958
-
The role of protein tyrosine phosphatases in the regulation of allergic asthma: Implication of TC-PTP and PTP-1B in the modulation of disease development
-
Pouliot P, Bergeron S, Marette A, Olivier M. The role of protein tyrosine phosphatases in the regulation of allergic asthma: implication of TC-PTP and PTP-1B in the modulation of disease development. Immunology. 1999;128(4)534-542
-
(1999)
Immunology
, vol.128
, Issue.4
-
-
Pouliot, P.1
Bergeron, S.2
Marette, A.3
Olivier, M.4
-
156
-
-
0037323994
-
Role of Src homology 2-containing-inositol 5′-phosphatase (SHIP) in mast cells and macrophages
-
156. Rauh MJ, Kalesnikoff J, Hughes M, Sly L, Lam V, Krystal G. Role of Src homology 2-containing-inositol 5′-phosphatase (SHIP) in mast cells and macrophages. Biochem Soc Trans. 2003 Feb;31(Pt 1):286-291 (Pubitemid 36241446)
-
(2003)
Biochemical Society Transactions
, vol.31
, Issue.1
-
-
Rauh, M.J.1
Kalesnikoff, J.2
Hughes, M.3
Sly, L.4
Lam, V.5
Krystal, G.6
-
157
-
-
0032535647
-
Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells
-
Dec 15
-
Huber M, Helgason CD, Scheid MP, Duronio V, Humphries RK, Krystal G. Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells. EMBO J. 1998 Dec 15;17(24): 7311-7319
-
(1998)
EMBO J
, vol.17
, Issue.24
-
-
Huber, M.1
Helgason, C.D.2
Scheid, M.P.3
Duronio, V.4
Humphries, R.K.5
Krystal, G.6
-
158
-
-
65549154373
-
Leishmania-induced IRAK-1 inactivation is mediated by SHP-1 interacting with an evolutionarily conserved KTIM motif
-
Abu-Dayyeh I, Shio MT, Sato S, Akira S, Cousineau B, Olivier M. Leishmania-induced IRAK-1 inactivation is mediated by SHP-1 interacting with an evolutionarily conserved KTIM motif. PLoS Negl Trop Dis. 2008;2(12):e305.
-
(2008)
PLoS Negl Trop Dis
, vol.2
, Issue.12
-
-
Abu-Dayyeh, I.1
Shio, M.T.2
Sato, S.3
Akira, S.4
Cousineau, B.5
Olivier, M.6
-
159
-
-
20444400257
-
Redox redux: Revisiting PTPs and the control of cell signaling
-
Jun 3
-
Tonks NK. Redox redux: revisiting PTPs and the control of cell signaling. Cell. 2005 Jun 3;121(5): 667-670
-
(2005)
Cell
, vol.121
, Issue.5
-
-
Tonks, N.K.1
-
160
-
-
33845929089
-
Protein flexibility and gand rigidity: A thermodynamic and kinetic study of ITAM-based ligand binding to Syk tandem SH2
-
Dec
-
de Mol NJ, Catalina MI, Dekker FJ, Fischer MJ, Heck AJ, Liskamp RM. Protein flexibility and gand rigidity: a thermodynamic and kinetic study of ITAM-based ligand binding to Syk tandem SH2. Chembiochem. 2005 Dec;6(12):2261-2270
-
(2005)
Chembiochem
, vol.6
, Issue.12
-
-
De Mol, N.J.1
Catalina, M.I.2
Dekker, F.J.3
Fischer, M.J.4
Heck, A.J.5
Liskamp, R.M.6
-
161
-
-
0034634638
-
Phosphorylation of Syk activation loop tyrosines is essential Syk function: An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody
-
DOI 10.1074/jbc.M004549200
-
161. Zhang J, Billingsley ML, Kincaid RL, Siraganian RP. Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody. J Biol Chem. 2000 Nov 10;275(45):35442-35447 (Pubitemid 30832568)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.45
-
-
Zhang, J.1
Billingsley, M.L.2
Kincaid, R.L.3
Siraganian, R.P.4
-
162
-
-
0034651636
-
Both stat5a and stat5b are required for antigen-induced eosinophil and T-cell recruitment into the tissue
-
Feb 15
-
Kagami S, Nakajima H, Kumano K, Suzuki K, Suto A, Imada K, Davey HW, Saito Y, Takatsu K, Leonard WJ, Iwamoto I. Both stat5a and stat5b are required for antigen-induced eosinophil and T-cell recruitment into the tissue. Blood. 2000 Feb 15;95(4):1370-1377
-
(2000)
Blood
, vol.95
, Issue.4
-
-
Kagami, S.1
Nakajima, H.2
Kumano, K.3
Suzuki, K.4
Suto, A.5
Imada, K.6
Davey, H.W.7
Saito, Y.8
Takatsu, K.9
Leonard, W.J.10
Iwamoto, I.11
-
163
-
-
0029913802
-
Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils
-
DOI 10.1084/jem.183.4.1407
-
163. Yousefi S, Hoessh DC, Blaser K, Mills GB, Simon HU. Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils. J Exp Med. 1996 Apr 1;183(4):1407-1414 (Pubitemid 26134284)
-
(1996)
Journal of Experimental Medicine
, vol.183
, Issue.4
-
-
Yousefi, S.1
Hoessli, D.C.2
Blaser, K.3
Mills, G.B.4
Simon, H.-U.5
-
164
-
-
0031671711
-
The mechanism of IL-5 signal transduction
-
Sep
-
Adachi T, Alam R. The mechanism of IL-5 signal transduction. Am J Physiol. 1998 Sep;275(3 Pt 1):C623-C633.
-
(1998)
Am J Physiol
, vol.275
, Issue.3 PART 1
-
-
Adachi, T.1
Alam, R.2
|