Essential role for the p110δ phosphoinositide 3-kinase in the allergic response

Nature

Volumn 431, Issue 7011, 2004, Pages 1007-1011

  Ali, Khaled ^a,b   Bilancio, Antonio ^a   Thomas, Matthew ^c   Pearce, Wayne ^a   Gilfillan, Alasdair M ^d   Tkaczyk, Christine ^d   Kuehn, Nicolas ^e   Gray, Alexander ^f   Giddings, June ^c   Peskett, Emma ^a   Fox, Roy ^c   Bruce, Ian ^c   Walker, Christoph ^c   Sawyer, Carol ^a,g   Okkenhaug, Klaus ^a,h   Finan, Peter ^c   Vanhaesebroeck, Bart ^a,b  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e Frimorfo   (Switzerland)

^f UNIVERSITY OF DUNDEE   (United Kingdom)

^g INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^h BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; CELL CULTURE; DRUG THERAPY; FLAMMABILITY; IMMUNOLOGY; PATHOLOGY;

CELL DIFFERENTIATION; DEGRANULATION; IMMUNOGLOBULINS;

ENZYME KINETICS;

2 MORPHOLINO 8 PHENYLCHROMONE; BETA N ACETYLHEXOSAMINIDASE; CELL PROTEIN; FC RECEPTOR; IC 87114; IMMUNOGLOBULIN E; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P110DELTA; STEM CELL FACTOR; UNCLASSIFIED DRUG; CYTOKINE; IMMUNOGLOBULIN E RECEPTOR; INTERLEUKIN 3; ISOENZYME; PIK3CD PROTEIN, MOUSE;

MEDICINE;

ALLERGY; ANAPHYLAXIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL ADHESION; CELL DIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DEGRANULATION; ENZYME ANALYSIS; GENE INACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; MAST CELL; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SECOND MESSENGER; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL COUNT; CELL MOTION; CYTOLOGY; DERMIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; ESSENTIAL GENE; GENETICS; HYPERSENSITIVITY; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANAPHYLAXIS; ANIMALS; CELL ADHESION; CELL COUNT; CELL DEGRANULATION; CELL MOVEMENT; CYTOKINES; DERMIS; GENES, ESSENTIAL; HUMANS; HYPERSENSITIVITY; INTERLEUKIN-3; ISOENZYMES; MAST CELLS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; RECEPTORS, IGE; SECOND MESSENGER SYSTEMS; STEM CELL FACTOR;

EID: 7244232917     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02991     Document Type: Article

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