Initiation and processing of signals from the B cell antigen receptor

Annual Review of Immunology

Volumn 15, Issue , 1997, Pages 453-479

  Reth, M ^a   Wienands, J ^a  

^a NONE

Author keywords

BCR; Ig ; Ig ; signal transduction; transducer complex

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN KINASE P60; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE;

ANTIGEN PRESENTATION; B LYMPHOCYTE ACTIVATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; EVOLUTION; HUMANS; MICE; MODELS, BIOLOGICAL; PROTEIN-TYROSINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION;

EID: 0030890949     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.immunol.15.1.453     Document Type: Review

References (17)

1. Reth M. 1992. Antigen receptors on B lymphocytes. Annu. Rev. Immunol. 10:97-121
2. Pleiman CM, D'Ambrosio D, Cambier JC. 1994. The B-cell antigen receptor complex: structure and signal transduction. Immunol. Today 15:393-99
3. Gold MR, DeFranco AL. 1994. Biochemistry of B lymphocyte activation. Adv. Immunol. 55:221-95
4. Neuberger MS, Patel KJ, Dariavach P, Nelms K, Peaker CJ, Williams GT. 1993. The mouse B-cell antigen receptor: definition and assembly of the core receptor of the five immunoglobulin isotypes. Immunol. Rev. 132:147-61
5. Williams GT, Dariavach P, Venkitaraman AR, Gilmore DJ, Neuberger MS. 1993. Membrane immunoglobulin without sheath or anchor. Mol. Immunol. 30:1427-32
6. Weiser P, Riesterer C, Reth M. 1994. The internalization of the IgG2a antigen receptor does not require the association with Ig-α and Ig-β but the activation of protein tyrosine kinases does. Eur. J. Immunol. 24:665-71
7. Gong S, Nussenzweig MC. 1996. Regulation of an early developmental check-point in the B cell pathway by Igβ. Science 272:411-14
8. Torres RM, Flaswinkel H, Reth M, Rajewsky K. 1996. Aberrant B cell development and immune response in mice with a compromised BCR complex. Science 272:1804-8
9. Reth M. 1989. Antigen receptor tail clue. Nature 338:383
10. Cambier JC. 1995. New nomenclature for the Reth motif (or ARH1/TAM/ ARAM/YXXL) [letter]. Immunol. Today 16:110
11. Wienands J, Freuler F, Baumann G. 1995. Tyrosine-phosphorylated forms of Ig-β CD22, TCR-ζ and HOSS are major ligands for tandem SH2 domains of Syk. Int. Iinmunol. 7:1701-8
12. Flaswinkel H, Reth M. 1994. Dual role of the tyrosine activation motif of the Ig-α protein during signal transduction via the B cell antigen receptor. EMBO J. 13:83-89
13. Sanchez M, Misulovin Z, Burkhardt AL, Mahajan S, Costa T, Bolen JB, Nussenzweig M. 1993. Signal transduction by immunoglobulin is mediated through Ig-α and Ig-β. J. Exp. Med. 178:1049-
14. Law DA, Chan VWF, Datta SK, DeFranco A. 1993. B-cell antigen receptors motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn. Curr. Biol. 3:645-57
15. Taddie JA, Hurley TR, Hardwick BS, Sefton BM. 1994. Activation of B- and T-cells by the cytoplasmic domains of the B-cell antigen receptor proteins Ig-α and Ig-β. J. Biol. Chem. 269:13,529-35
16. Wienands J, Larbolette O, Reth M. 1996. Evidence for a preformed transducer complex organized by the B cell antigen receptor. Proc. Natl. Acad. Sci. USA 93:7865-70
17. Gold MR, Matsuuchi L, Kelly RB, DeFranco AL. 1991. Tyrosine phosphorylation of components of the B-cell antigen receptors following receptor crosslinking. Proc. Natl. Acad. Sci. USA 88:3436-40