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Volumn 2, Issue 1, 2009, Pages 83-94

Group I metabotropic glutamate receptors: Involvement in drug-seeking and drug-induced plasticity

Author keywords

Addiction; Cocaine; Dependence; Ethanol; Metabotropic glutamate receptor; Motivation; Reward

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 3 [(2 METHYL 4 THIAZOLYL)ETHYNYL]PYRIDINE; ALCOHOL; CANNABINOID; COCAINE; DIZOCILPINE; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 5; MORPHINE; OPIATE; ALCOHOL DERIVATIVE; CALCIUM; METABOTROPIC GLUTAMATE RECEPTOR TYPE 1; METABOTROPIC RECEPTOR; NICOTINE; OPIATE PEPTIDE;

EID: 70449654395     PISSN: 18744672     EISSN: 18744702     Source Type: Journal    
DOI: 10.2174/1874467210902010083     Document Type: Article
Times cited : (39)

References (202)
  • 2
    • 0036715629 scopus 로고    scopus 로고
    • Drug addictions: Towards socially accepted and medically treatable diseases
    • Pouletty, P. Drug addictions: towards socially accepted and medically treatable diseases. Nat. Rev. Drug Discov. 2002, 1, 731-6.
    • (2002) Nat. Rev. Drug Discov , vol.1 , pp. 731-736
    • Pouletty, P.1
  • 3
    • 0003845462 scopus 로고    scopus 로고
    • Central Intelligence Agency, Office of Public Affairs: Washington, DC
    • Central Intelligence Agency. The World Factbook. Office of Public Affairs: Washington, DC 2008.
    • (2008) The World Factbook
  • 4
    • 0035489031 scopus 로고    scopus 로고
    • Addiction and the brain: The neurobiology of compulsion and its persistence
    • Hyman, S. E.; Malenka, R. C. Addiction and the brain: The neurobiology of compulsion and its persistence. Nat. Rev. Neurosci. 2001, 2, 695-703.
    • (2001) Nat. Rev. Neurosci , vol.2 , pp. 695-703
    • Hyman, S.E.1    Malenka, R.C.2
  • 5
    • 0030756351 scopus 로고    scopus 로고
    • Drug abuse: Hedonic homeostatic dysregulation
    • Koob, G. F.; LeMoal, M. Drug abuse: Hedonic homeostatic dysregulation. Science 1997, 278, 52-58.
    • (1997) Science , vol.278 , pp. 52-58
    • Koob, G.F.1    Lemoal, M.2
  • 6
    • 0035199891 scopus 로고    scopus 로고
    • Drug addiction, dysregulation of reward, and allostasis
    • Koob, G. F.; Le Moal, M. Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 2001, 24, 97-129.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 97-129
    • Koob, G.F.1    Le Moal, M.2
  • 7
    • 27644548739 scopus 로고    scopus 로고
    • Plasticity of reward neurocircuitry and the 'dark side' of drug addiction
    • Koob, G. F.; Le Moal, M. Plasticity of reward neurocircuitry and the 'dark side' of drug addiction. Nat. Neurosci. 2005, 8, 1442-1444.
    • (2005) Nat. Neurosci , vol.8 , pp. 1442-1444
    • Koob, G.F.1    Le Moal, M.2
  • 8
    • 0019048651 scopus 로고
    • The opponent-process theory of acquired motivation - the costs of pleasure and the benefits of pain
    • Solomon, R. L. The opponent-process theory of acquired motivation - the costs of pleasure and the benefits of pain. Am. Psychol. 1980, 35, 691-712.
    • (1980) Am. Psychol , vol.35 , pp. 691-712
    • Solomon, R.L.1
  • 9
    • 0016045280 scopus 로고
    • Opponent-process theory of motivation.1. temporal dynamics of affect
    • Solomon, R. L.; Corbit, J. D. Opponent-process theory of motivation.1. temporal dynamics of affect. Psychol. Rev. 1974, 81, 119-145.
    • (1974) Psychol. Rev , vol.81 , pp. 119-145
    • Solomon, R.L.1    Corbit, J.D.2
  • 10
    • 0035849890 scopus 로고    scopus 로고
    • Neuroadaptation: Incubation of cocaine craving after withdrawal
    • Grimm, J. W.; Hope, B. T.; Wise, R. A.; Shaham, Y. Neuroadaptation: Incubation of cocaine craving after withdrawal. Nature 2001, 412, 141-142.
    • (2001) Nature , vol.412 , pp. 141-142
    • Grimm, J.W.1    Hope, B.T.2    Wise, R.A.3    Shaham, Y.4
  • 11
    • 0027305458 scopus 로고
    • The neural basis of drug craving: An incentive-sensitization theory of addiction
    • Robinson, T. E.; Berridge, K. C. The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Res. Rev. 1993, 18, 247-291.
    • (1993) Brain Res. Rev , vol.18 , pp. 247-291
    • Robinson, T.E.1    Berridge, K.C.2
  • 13
    • 0032423613 scopus 로고    scopus 로고
    • What is the role of dopamine in reward: Hedonic impact, reward learning or incentive salience?
    • Berridge, K. C.; Robinson, T. E. What is the role of dopamine in reward: hedonic impact, reward learning or incentive salience? Brain Res. Rev. 1998, 28, 309-369.
    • (1998) Brain Res. Rev , vol.28 , pp. 309-369
    • Berridge, K.C.1    Robinson, T.E.2
  • 14
    • 0033842872 scopus 로고    scopus 로고
    • The psychology and neurobiology of addiction: An incentive-sensitization view
    • Robinson, T. E.; Berridge, K. C. The psychology and neurobiology of addiction: an incentive-sensitization view. Addiction 2000, 95, S91-S117.
    • (2000) Addiction , vol.95
    • Robinson, T.E.1    Berridge, K.C.2
  • 15
    • 0035139761 scopus 로고    scopus 로고
    • Incentive-sensitization and addiction
    • Robinson, T. E.; Berridge, K. C. Incentive-sensitization and addiction. Addiction 2001, 96, 103-114.
    • (2001) Addiction , vol.96 , pp. 103-114
    • Robinson, T.E.1    Berridge, K.C.2
  • 16
    • 0035260641 scopus 로고    scopus 로고
    • Molecular basis of long-term plasticity underlying addiction
    • Nestler, E. J. Molecular basis of long-term plasticity underlying addiction. Nat. Rev. Neurosci. 2001, 2, 119-128.
    • (2001) Nat. Rev. Neurosci , vol.2 , pp. 119-128
    • Nestler, E.J.1
  • 17
    • 0031889178 scopus 로고    scopus 로고
    • A motivational learning hypothesis of the role of mesolimbic dopamine in compulsive drug use
    • Di Chiara, G. A motivational learning hypothesis of the role of mesolimbic dopamine in compulsive drug use. J. Psychopharmacol. 1998, 12, 54-67.
    • (1998) J. Psychopharmacol , vol.12 , pp. 54-67
    • Di Chiara, G.1
  • 18
    • 0032980748 scopus 로고    scopus 로고
    • Drug addiction as dopamine-dependent associative learning disorder
    • Di Chiara, G. Drug addiction as dopamine-dependent associative learning disorder. Eur. J. Pharmacol. 1999, 375, 13-30.
    • (1999) Eur. J. Pharmacol , vol.375 , pp. 13-30
    • Di Chiara, G.1
  • 19
    • 0036881831 scopus 로고    scopus 로고
    • Limbic-striatal memory systems and drug addiction
    • Robbins, T. W.; Everitt, J. Limbic-striatal memory systems and drug addiction. Neurobiol. Learn. Mem. 2002, 78, 625-636.
    • (2002) Neurobiol. Learn. Mem , vol.78 , pp. 625-636
    • Robbins, T.W.1    Everitt, J.2
  • 20
    • 0000103011 scopus 로고
    • La fine structures des centres nerveux
    • Ramon y Cajal, S. La fine structures des centres nerveux. Proc. R. Soc. Lond. 1894, 55, 444-468.
    • (1894) Proc. R. Soc. Lond , vol.55 , pp. 444-468
    • Ramon y Cajal, S.1
  • 21
    • 36549075574 scopus 로고    scopus 로고
    • Synaptic plasticity: Multiple forms, functions, and mechanisms
    • Citri, A.; Malenka, R. C. Synaptic plasticity: Multiple forms, functions, and mechanisms. Neuropsychopharmacology 2008, 33, 18-41.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 18-41
    • Citri, A.1    Malenka, R.C.2
  • 22
    • 5344241223 scopus 로고    scopus 로고
    • An embarrassment of riches
    • LTP and LTD
    • Malenka, R. C.; Bear, M. F. LTP and LTD: An embarrassment of riches. Neuron 2004, 44, 5-21.
    • (2004) Neuron , vol.44 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 23
    • 2342539137 scopus 로고    scopus 로고
    • Learning mechanisms in addiction: Synaptic plasticity in the ventral tegmental area as a result of exposure to drugs of abuse
    • Kauer, J. A. Learning mechanisms in addiction: Synaptic plasticity in the ventral tegmental area as a result of exposure to drugs of abuse. Annu. Rev. Physiol. 2004, 66, 447-475.
    • (2004) Annu. Rev. Physiol , vol.66 , pp. 447-475
    • Kauer, J.A.1
  • 24
    • 48749121466 scopus 로고    scopus 로고
    • Long-term administration of cocaine or serotonin reuptake inhibitors results in anatomical and neurochemical changes in noradrenergic, dopaminergic, and serotonin pathways
    • Horne, M. K.; Lee, J.; Chen, F.; Lanning, K.; Tomas, D.; Lawrence, A. J. Long-term administration of cocaine or serotonin reuptake inhibitors results in anatomical and neurochemical changes in noradrenergic, dopaminergic, and serotonin pathways. J. Neurochem. 2008, 106, 1731-1744.
    • (2008) J. Neurochem , vol.106 , pp. 1731-1744
    • Horne, M.K.1    Lee, J.2    Chen, F.3    Lanning, K.4    Tomas, D.5    Lawrence, A.J.6
  • 25
    • 0035978760 scopus 로고    scopus 로고
    • Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons
    • Ungless, M. A.; Whistler, J. L.; Malenka, R. C.; Bonci, A. Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons. Nature 2001, 411, 583-587.
    • (2001) Nature , vol.411 , pp. 583-587
    • Ungless, M.A.1    Whistler, J.L.2    Malenka, R.C.3    Bonci, A.4
  • 26
    • 0030249901 scopus 로고    scopus 로고
    • Inhibition by MK-801 of morphine- induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice
    • Kim, H. S.; Jang, C. G.; Park, W. K. Inhibition by MK-801 of morphine- induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice. Pharmacol. Biochem. Behav. 1996, 55, 11-17.
    • (1996) Pharmacol. Biochem. Behav , vol.55 , pp. 11-17
    • Kim, H.S.1    Jang, C.G.2    Park, W.K.3
  • 27
    • 0027135373 scopus 로고
    • Blockade of the acquisition of cocaine self-administration by the NMDA antagonist MK-801 (Dizocilpine)
    • Schenk, S.; Valadez, A.; Worley, C. M.; McNamara, C. Blockade of the acquisition of cocaine self-administration by the NMDA antagonist MK-801 (Dizocilpine). Behav. Pharmacol. 1993, 4, 652-659.
    • (1993) Behav. Pharmacol , vol.4 , pp. 652-659
    • Schenk, S.1    Valadez, A.2    Worley, C.M.3    McNamara, C.4
  • 28
    • 0029888897 scopus 로고    scopus 로고
    • Inhibition by MK-801 of cocaine-induced sensitization, conditioned place preference, and dopamine-receptor supersensitivity in mice
    • Kim, H. S.; Park, W. K.; Jang, C. G.; Oh, S. Inhibition by MK-801 of cocaine-induced sensitization, conditioned place preference, and dopamine-receptor supersensitivity in mice. Brain Res. Bull. 1996, 40, 201-207.
    • (1996) Brain Res. Bull , vol.40 , pp. 201-207
    • Kim, H.S.1    Park, W.K.2    Jang, C.G.3    Oh, S.4
  • 29
    • 0027362828 scopus 로고
    • Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine
    • Kalivas, P. W.; Alesdatter, J. E. Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine. J. Pharmacol. Exp. Ther. 1993, 267, 486-495.
    • (1993) J. Pharmacol. Exp. Ther , vol.267 , pp. 486-495
    • Kalivas, P.W.1    Alesdatter, J.E.2
  • 30
    • 33746069362 scopus 로고    scopus 로고
    • Relationship between development of cross-sensitization to MK-801 and delayed increases in glutamate levels in the nucleus accumbens induced by a high dose of methamphetamine
    • Ito, K.; Abekawa, T.; Koyama, T. Relationship between development of cross-sensitization to MK-801 and delayed increases in glutamate levels in the nucleus accumbens induced by a high dose of methamphetamine. Psychopharmacology 2006, 187, 293-302.
    • (2006) Psychopharmacology , vol.187 , pp. 293-302
    • Ito, K.1    Abekawa, T.2    Koyama, T.3
  • 31
    • 0022725590 scopus 로고
    • Enduring changes in brain and behavior produced by chronic amphetamine administration - a review and evaluation of animal-models of amphetamine psychosis
    • Robinson, T. E.; Becker, J. B. Enduring changes in brain and behavior produced by chronic amphetamine administration - a review and evaluation of animal-models of amphetamine psychosis. Brain Res. Rev. 1986, 11, 157-198.
    • (1986) Brain Res. Rev , vol.11 , pp. 157-198
    • Robinson, T.E.1    Becker, J.B.2
  • 32
    • 0025751604 scopus 로고
    • Dopamine transmission in the initiation and expression of drug-induced and stress-induced sensitization of motoractivity
    • Kalivas, P. W.; Stewart, J. Dopamine transmission in the initiation and expression of drug-induced and stress-induced sensitization of motoractivity. Brain Res. Rev. 1991, 16, 223-244.
    • (1991) Brain Res. Rev , vol.16 , pp. 223-244
    • Kalivas, P.W.1    Stewart, J.2
  • 33
    • 0028815346 scopus 로고
    • Evidence of a complete independence of the neurobiological substrates for the induction and expression of behavioral sensitization to amphetamine
    • Cador, M.; Bjijou, Y.; Stinus, L. Evidence of a complete independence of the neurobiological substrates for the induction and expression of behavioral sensitization to amphetamine. Neuroscience 1995, 65, 385-395.
    • (1995) Neuroscience , vol.65 , pp. 385-395
    • Cador, M.1    Bjijou, Y.2    Stinus, L.3
  • 34
    • 0023502576 scopus 로고
    • Sensitization occurs to the locomotor effects of morphine and the specific mu-opioid receptor agonist, dago, administered repeatedly to the ventral tegmental area but not to the aucleusaccumbens
    • Vezina, P.; Kalivas, P. W.; Stewart, J. Sensitization occurs to the locomotor effects of morphine and the specific mu-opioid receptor agonist, dago, administered repeatedly to the ventral tegmental area but not to the aucleusaccumbens. Brain Res. 1987, 417, 51-58.
    • (1987) Brain Res , vol.417 , pp. 51-58
    • Vezina, P.1    Kalivas, P.W.2    Stewart, J.3
  • 35
    • 35548930211 scopus 로고    scopus 로고
    • Synaptic plasticity and addiction
    • Kauer, J. A.; Malenka, R. C. Synaptic plasticity and addiction. Nat. Rev. Neurosci. 2007, 8, 844-858.
    • (2007) Nat. Rev. Neurosci , vol.8 , pp. 844-858
    • Kauer, J.A.1    Malenka, R.C.2
  • 36
    • 0025371482 scopus 로고
    • The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurons
    • Smith, A. D.; Bolam, J. P. The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurons. Trends Neurosci. 1990, 13, 259-265.
    • (1990) Trends Neurosci , vol.13 , pp. 259-265
    • Smith, A.D.1    Bolam, J.P.2
  • 37
    • 0035283646 scopus 로고    scopus 로고
    • Cocaine self-administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortex
    • Robinson, T. E.; Gorny, G.; Mitton, E.; Kolb, B. Cocaine self-administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortex. Synapse 2001, 39, 257-266.
    • (2001) Synapse , vol.39 , pp. 257-266
    • Robinson, T.E.1    Gorny, G.2    Mitton, E.3    Kolb, B.4
  • 38
    • 0032905108 scopus 로고    scopus 로고
    • Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine
    • Robinson, T. E.; Kolb, B. Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine. Eur. J. Neurosci. 1999, 11, 1598-1604.
    • (1999) Eur. J. Neurosci , vol.11 , pp. 1598-1604
    • Robinson, T.E.1    Kolb, B.2
  • 39
    • 33644748177 scopus 로고    scopus 로고
    • Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor- containing medium spiny neurons in nucleus accumbens
    • Lee, K.-W.; Kim, Y.; Kim, A. M.; Helmin, K.; Nairn, A. C.; Greengard, P. Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor- containing medium spiny neurons in nucleus accumbens. Proc. Natl. Acad. Sci. USA 2006, 103, 3399-3404.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 3399-3404
    • Lee, K.-W.1    Kim, Y.2    Kim, A.M.3    Helmin, K.4    Nairn, A.C.5    Greengard, P.6
  • 40
    • 0037724220 scopus 로고    scopus 로고
    • Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5
    • Norrholm, S. D.; Bibb, J. A.; Nestler, E. J.; Ouimet, C. C.; Taylor, J. R.; Greengard, P. Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5. Neuroscience 2003, 119, 619-619.
    • (2003) Neuroscience , vol.119 , pp. 619-619
    • Norrholm, S.D.1    Bibb, J.A.2    Nestler, E.J.3    Ouimet, C.C.4    Taylor, J.R.5    Greengard, P.6
  • 41
    • 0033566311 scopus 로고    scopus 로고
    • Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats
    • Robinson, T. E.; Kolb, B. Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats. Synapse 1999, 33, 160-162.
    • (1999) Synapse , vol.33 , pp. 160-162
    • Robinson, T.E.1    Kolb, B.2
  • 42
    • 33846345905 scopus 로고    scopus 로고
    • Chronic alcohol drinking alters neuronal dendritic spines in the brain reward center nucleus accumbens
    • Zhou, F. C.; Anthony, B.; Dunn, K. W.; Lindquist, W. B.; Xu, Z. C.; Deng, P. Chronic alcohol drinking alters neuronal dendritic spines in the brain reward center nucleus accumbens. Brain Res. 2007, 1134, 148-161.
    • (2007) Brain Res , vol.1134 , pp. 148-161
    • Zhou, F.C.1    Anthony, B.2    Dunn, K.W.3    Lindquist, W.B.4    Xu, Z.C.5    Deng, P.6
  • 43
    • 0029048034 scopus 로고
    • D1 receptors modulate glutamate transmission in the ventral tegmental area
    • Kalivas, P. W.; Duffy, P. D1 receptors modulate glutamate transmission in the ventral tegmental area. J. Neurosci. 1995, 15, 5379-5388.
    • (1995) J. Neurosci , vol.15 , pp. 5379-5388
    • Kalivas, P.W.1    Duffy, P.2
  • 44
    • 0031950670 scopus 로고    scopus 로고
    • Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area
    • Kalivas, P. W.; Duffy, P. Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area. J. Neurochem. 1998, 70, 1497-1502.
    • (1998) J. Neurochem , vol.70 , pp. 1497-1502
    • Kalivas, P.W.1    Duffy, P.2
  • 45
    • 0035783681 scopus 로고    scopus 로고
    • Alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposure
    • Hotsenpiller, G.; Giorgetti, M.; Wolf, M. E. Alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposure. Eur. J. Neurosci. 2001, 14, 1843-1855.
    • (2001) Eur. J. Neurosci , vol.14 , pp. 1843-1855
    • Hotsenpiller, G.1    Giorgetti, M.2    Wolf, M.E.3
  • 46
    • 0036945669 scopus 로고    scopus 로고
    • Extracellular glutamate levels in prefrontal cortex during the expression of associative responses to cocaine related stimuli
    • Hotsenpiller, G.; Wolf, M. E. Extracellular glutamate levels in prefrontal cortex during the expression of associative responses to cocaine related stimuli. Neuropharmacology 2002, 43, 1218-1229.
    • (2002) Neuropharmacology , vol.43 , pp. 1218-1229
    • Hotsenpiller, G.1    Wolf, M.E.2
  • 47
    • 0037693859 scopus 로고    scopus 로고
    • Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior
    • McFarland, K.; Lapish, C. C.; Kalivas, P. W. Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. J. Neurosci. 2003, 23, 3531-3537.
    • (2003) J. Neurosci , vol.23 , pp. 3531-3537
    • McFarland, K.1    Lapish, C.C.2    Kalivas, P.W.3
  • 48
    • 0037209158 scopus 로고    scopus 로고
    • Critical role for ventral tegmental glutamate in preference for a cocaine-conditioned environment
    • Harris, G. C.; Aston-Jones, G. Critical role for ventral tegmental glutamate in preference for a cocaine-conditioned environment. Neuropsychopharmacology 2003, 28, 73-76.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 73-76
    • Harris, G.C.1    Aston-Jones, G.2
  • 49
    • 0038502133 scopus 로고    scopus 로고
    • Brain circuitry and the reinstatement of cocaine-seeking behavior
    • Kalivas, P. W.; McFarland, K. Brain circuitry and the reinstatement of cocaine-seeking behavior. Psychopharmacology 2003, 168, 44-56.
    • (2003) Psychopharmacology , vol.168 , pp. 44-56
    • Kalivas, P.W.1    McFarland, K.2
  • 51
    • 17744387125 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor structure and pharmacology
    • Kew, J. N. C.; Kemp, J. A. Ionotropic and metabotropic glutamate receptor structure and pharmacology. Psychopharmacology 2005, 179, 4-29.
    • (2005) Psychopharmacology , vol.179 , pp. 4-29
    • Kew, J.N.C.1    Kemp, J.A.2
  • 52
    • 0022370635 scopus 로고
    • Glutamate stimulates inositol phosphate formation in striatal neurons
    • Sladeczek, F.; Pin, J. P.; Recasens, M.; Bockaert, J.; Weiss, S. Glutamate stimulates inositol phosphate formation in striatal neurons. Nature 1985, 317, 717-719.
    • (1985) Nature , vol.317 , pp. 717-719
    • Sladeczek, F.1    Pin, J.P.2    Recasens, M.3    Bockaert, J.4    Weiss, S.5
  • 53
    • 0023092256 scopus 로고
    • A new type of glutamate receptor linked to inositol phospholipid metabolism
    • Sugiyama, H.; Ito, I.; Hirono, C. A new type of glutamate receptor linked to inositol phospholipid metabolism. Nature 1987, 325, 531-533.
    • (1987) Nature , vol.325 , pp. 531-533
    • Sugiyama, H.1    Ito, I.2    Hirono, C.3
  • 55
    • 0026681594 scopus 로고
    • Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction
    • Abe, T.; Sugihara, H.; Nawa, H.; Shigemoto, R.; Mizuno, N.; Nakanishi, S. Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction. J. Biol. Chem. 1992, 267, 13361-13368.
    • (1992) J. Biol. Chem , vol.267 , pp. 13361-13368
    • Abe, T.1    Sugihara, H.2    Nawa, H.3    Shigemoto, R.4    Mizuno, N.5    Nakanishi, S.6
  • 57
    • 0027232329 scopus 로고
    • Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4- phosphonobutyrate
    • Nakajima, Y.; Iwakabe, H.; Akazawa, C.; Nawa, H.; Shigemoto, R.; Mizuno, N.; Nakanishi, S. Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4- phosphonobutyrate. J. Biol. Chem. 1993, 268, 11868-11873.
    • (1993) J. Biol. Chem , vol.268 , pp. 11868-11873
    • Nakajima, Y.1    Iwakabe, H.2    Akazawa, C.3    Nawa, H.4    Shigemoto, R.5    Mizuno, N.6    Nakanishi, S.7
  • 58
    • 77953756390 scopus 로고
    • Molecular characterization of a new metabotropic glutamate-receptor mGluR7 coupled to inhibitory cyclic-amp signal-transduction
    • Okamoto, N.; Hori, S.; Akazawa, C.; Hayashi, Y.; Shigemoto, R.; Mizuno, N.; Honda, Y.; Nakanishi, S. Molecular characterization of a new metabotropic glutamate-receptor mGluR7 coupled to inhibitory cyclic-amp signal-transduction. Invest. Ophth. Vis. Sci. 1994, 35, 1584-1584.
    • (1994) Invest. Ophth. Vis. Sci , vol.35 , pp. 1584-1584
    • Okamoto, N.1    Hori, S.2    Akazawa, C.3    Hayashi, Y.4    Shigemoto, R.5    Mizuno, N.6    Honda, Y.7    Nakanishi, S.8
  • 59
    • 0028968702 scopus 로고
    • A novel metabotropic glutamate-receptor expressed in the retina and olfactory-bulb
    • Duvoisin, R. M.; Zhang, C. X.; Ramonell, K. A novel metabotropic glutamate-receptor expressed in the retina and olfactory-bulb. J. Neurosci. 1995, 15, 3075-3083.
    • (1995) J. Neurosci , vol.15 , pp. 3075-3083
    • Duvoisin, R.M.1    Zhang, C.X.2    Ramonell, K.3
  • 60
    • 0026093312 scopus 로고
    • Sequence and expression of a metabotropic glutamate receptor
    • Masu, M.; Tanabe, Y.; Tsuchida, K.; Shigemoto, R.; Nakanishi, S. Sequence and expression of a metabotropic glutamate receptor. Nature 1991, 349, 760-765.
    • (1991) Nature , vol.349 , pp. 760-765
    • Masu, M.1    Tanabe, Y.2    Tsuchida, K.3    Shigemoto, R.4    Nakanishi, S.5
  • 61
    • 0030995878 scopus 로고    scopus 로고
    • Pharmacology and functions of metabotropic glutamate receptors
    • Conn, P. J.; Pin, J. P. Pharmacology and functions of metabotropic glutamate receptors. Annu. Rev. Pharmacol. Toxicol. 1997, 37, 205-237.
    • (1997) Annu. Rev. Pharmacol. Toxicol , vol.37 , pp. 205-237
    • Conn, P.J.1    Pin, J.P.2
  • 62
    • 0035914405 scopus 로고    scopus 로고
    • Heterodimerization of calcium sensing receptors with metabotropic glutamate receptors in neurons
    • Gama, L.; Wilt, S. G.; Breitwieser, G. E. Heterodimerization of calcium sensing receptors with metabotropic glutamate receptors in neurons. J. Biol. Chem. 2001, 276, 39053-39059.
    • (2001) J. Biol. Chem , vol.276 , pp. 39053-39059
    • Gama, L.1    Wilt, S.G.2    Breitwieser, G.E.3
  • 65
    • 0035894851 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor
    • Peavy, R. D.; Chang, M. S. S.; Sanders-Bush, E.; Conn, P. J. Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor. J. Neurosci. 2001, 21, 9619-9628.
    • (2001) J. Neurosci , vol.21 , pp. 9619-9628
    • Peavy, R.D.1    Chang, M.S.S.2    Sanders-Bush, E.3    Conn, P.J.4
  • 66
    • 0036799241 scopus 로고    scopus 로고
    • Activation of mGluR5 modulates GABA(A) receptor function in retinal amacrine cells
    • Hoffpauir, B. K.; Gleason, E. L. Activation of mGluR5 modulates GABA(A) receptor function in retinal amacrine cells. J. Neurophysiol. 2002, 88, 1766-1776.
    • (2002) J. Neurophysiol , vol.88 , pp. 1766-1776
    • Hoffpauir, B.K.1    Gleason, E.L.2
  • 67
    • 3843087453 scopus 로고    scopus 로고
    • A single in vivo exposure to cocaine abolishes endocannabinoid-mediated long-term depression in the nucleus accumbens
    • Fourgeaud, L.; Mato, S.; Bouchet, D.; Hemar, A.; Worley, P. F.; Manzoni, O. J. A single in vivo exposure to cocaine abolishes endocannabinoid-mediated long-term depression in the nucleus accumbens. J. Neurosci. 2004, 24, 6939-6945.
    • (2004) J. Neurosci , vol.24 , pp. 6939-6945
    • Fourgeaud, L.1    Mato, S.2    Bouchet, D.3    Hemar, A.4    Worley, P.F.5    Manzoni, O.J.6
  • 68
    • 0347722460 scopus 로고    scopus 로고
    • Exogenous and endogenous cannabinoids control synaptic transmission in mice nucleus accumbens
    • Robbe, D.; Alonso, G.; Manzoni, O. J. Exogenous and endogenous cannabinoids control synaptic transmission in mice nucleus accumbens. Ann. N. Y. Acad. Sci. 2003, 1003, 212-225.
    • (2003) Ann. N. Y. Acad. Sci , vol.1003 , pp. 212-225
    • Robbe, D.1    Alonso, G.2    Manzoni, O.J.3
  • 69
    • 33645236206 scopus 로고    scopus 로고
    • Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration
    • Grueter, B. A.; Gosnell, H. B.; Olsen, C. M.; Schramm-Sapyta, N. L.; Nekrasova, T.; Landreth, G. E.; Winder, D. G. Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration. J. Neurosci. 2006, 26, 3210-3219.
    • (2006) J. Neurosci , vol.26 , pp. 3210-3219
    • Grueter, B.A.1    Gosnell, H.B.2    Olsen, C.M.3    Schramm-Sapyta, N.L.4    Nekrasova, T.5    Landreth, G.E.6    Winder, D.G.7
  • 70
    • 0029098659 scopus 로고
    • Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
    • Kornau, H.-C.; Schenker, L. T.; Kennedy, M. B.; Seeburg, P. H. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 1995, 269, 1737-1740.
    • (1995) Science , vol.269 , pp. 1737-1740
    • Kornau, H.-C.1    Schenker, L.T.2    Kennedy, M.B.3    Seeburg, P.H.4
  • 72
    • 0033490463 scopus 로고    scopus 로고
    • G-protein-independent signaling mediated by metabotropic glutamate receptors
    • Heuss, C.; Scanziani, M.; Gahwiler, B. H.; Gerber, U. G-protein-independent signaling mediated by metabotropic glutamate receptors. Nat. Neurosci. 1999, 2, 1070-1077.
    • (1999) Nat. Neurosci , vol.2 , pp. 1070-1077
    • Heuss, C.1    Scanziani, M.2    Gahwiler, B.H.3    Gerber, U.4
  • 73
    • 0036092612 scopus 로고    scopus 로고
    • Postsynaptic induction and presynaptic expression of group 1 mGluR-dependent LTD in the hippocampal CA1 region
    • Watabe, A. M.; Carlisle, H. J.; O'Dell, T. J. Postsynaptic induction and presynaptic expression of group 1 mGluR-dependent LTD in the hippocampal CA1 region. J. Neurophysiol. 2002, 87, 1395-1403.
    • (2002) J. Neurophysiol , vol.87 , pp. 1395-1403
    • Watabe, A.M.1    Carlisle, H.J.2    O'Dell, T.J.3
  • 74
    • 0030014918 scopus 로고    scopus 로고
    • Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus
    • Lujan, R.; Nusser, Z.; Roberts, J. D. B.; Shigemoto, R.; Somogyi, P. Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus. Eur. J. Neurosci. 1996, 8, 1488-1500.
    • (1996) Eur. J. Neurosci , vol.8 , pp. 1488-1500
    • Lujan, R.1    Nusser, Z.2    Roberts, J.D.B.3    Shigemoto, R.4    Somogyi, P.5
  • 75
    • 0032509812 scopus 로고    scopus 로고
    • Localization of mGluR1a-like immunoreactivity and mGluR5-like immunoreactivity in identified populations of striatal neurons
    • Tallaksen-Greene, S. J.; Kaatz, K. W.; Romano, C.; Albin, R. L. Localization of mGluR1a-like immunoreactivity and mGluR5-like immunoreactivity in identified populations of striatal neurons. Brain Res. 1998, 780, 210-217.
    • (1998) Brain Res , vol.780 , pp. 210-217
    • Tallaksen-Greene, S.J.1    Kaatz, K.W.2    Romano, C.3    Albin, R.L.4
  • 76
    • 0035124349 scopus 로고    scopus 로고
    • Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges
    • Attucci, S.; Carla, V.; Mannaioni, G.; Moroni, F. Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges. Br. J. Pharmacol. 2001, 132, 799-806.
    • (2001) Br. J. Pharmacol , vol.132 , pp. 799-806
    • Attucci, S.1    Carla, V.2    Mannaioni, G.3    Moroni, F.4
  • 77
    • 0034332480 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
    • Awad, H.; Hubert, G. W.; Smith, Y.; Levey, A. I.; Conn, P. J. Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. J. Neurosci. 2000, 20, 7871-7879.
    • (2000) J. Neurosci , vol.20 , pp. 7871-7879
    • Awad, H.1    Hubert, G.W.2    Smith, Y.3    Levey, A.I.4    Conn, P.J.5
  • 78
    • 0032907608 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Electrophysiological properties and role in plasticity
    • Anwyl, R. Metabotropic glutamate receptors: electrophysiological properties and role in plasticity. Brain Res. Rev. 1999, 29, 83-120.
    • (1999) Brain Res. Rev , vol.29 , pp. 83-120
    • Anwyl, R.1
  • 79
    • 0035889975 scopus 로고    scopus 로고
    • Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: A potential role for Homer
    • Swanson, C. J.; Baker, D. A.; Carson, D.; Worley, P. F.; Kalivas, P. W. Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: A potential role for Homer. J. Neurosci. 2001, 21, 9043-9052.
    • (2001) J. Neurosci , vol.21 , pp. 9043-9052
    • Swanson, C.J.1    Baker, D.A.2    Carson, D.3    Worley, P.F.4    Kalivas, P.W.5
  • 81
    • 0027378595 scopus 로고
    • Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain
    • Shigemoto, R.; Nomura, S.; Ohishi, H.; Sugihara, H.; Nakanishi, S.; Mizuno, N. Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain. Neurosci. Lett. 1993, 163, 53-57.
    • (1993) Neurosci. Lett , vol.163 , pp. 53-57
    • Shigemoto, R.1    Nomura, S.2    Ohishi, H.3    Sugihara, H.4    Nakanishi, S.5    Mizuno, N.6
  • 83
    • 1442275398 scopus 로고    scopus 로고
    • Metabotropic glutamate 1 receptor distribution and occupancy in the rat brain: A quantitative autoradiographic study using H-3 R214127
    • Lavreysen, H.; Pereira, S. N.; Leysen, J. E.; Langlois, X.; Lesage, A. S. J. Metabotropic glutamate 1 receptor distribution and occupancy in the rat brain: a quantitative autoradiographic study using H-3 R214127. Neuropharmacology 2004, 46, 609-619.
    • (2004) Neuropharmacology , vol.46 , pp. 609-619
    • Lavreysen, H.1    Pereira, S.N.2    Leysen, J.E.3    Langlois, X.4    Lesage, A.S.J.5
  • 84
    • 0033028462 scopus 로고    scopus 로고
    • Group I mGlu receptor modulation of dopamine release in the rat striatum in vivo
    • Bruton, R. F.; Ge, J.; Barnes, N. M. Group I mGlu receptor modulation of dopamine release in the rat striatum in vivo. Eur. J. Pharmacol. 1999, 369, 175-181.
    • (1999) Eur. J. Pharmacol , vol.369 , pp. 175-181
    • Bruton, R.F.1    Ge, J.2    Barnes, N.M.3
  • 85
    • 33847730308 scopus 로고    scopus 로고
    • Stimulation of group I mGlu receptors in the ventrotegmental area enhances extracellular dopamine in the rat medial prefrontal cortex
    • Renoldi, G.; Calcagno, E.; Borsini, F.; Invernizzi, R. W. Stimulation of group I mGlu receptors in the ventrotegmental area enhances extracellular dopamine in the rat medial prefrontal cortex. J. Neurochem. 2007, 100, 1658-1666.
    • (2007) J. Neurochem , vol.100 , pp. 1658-1666
    • Renoldi, G.1    Calcagno, E.2    Borsini, F.3    Invernizzi, R.W.4
  • 86
    • 0035089240 scopus 로고    scopus 로고
    • Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes
    • Page, G.; Peeters, M.; Najimi, M.; Maloteaux, J. M.; Hermans, E. Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes. J. Neurochem. 2001, 76, 1282-1290.
    • (2001) J. Neurochem , vol.76 , pp. 1282-1290
    • Page, G.1    Peeters, M.2    Najimi, M.3    Maloteaux, J.M.4    Hermans, E.5
  • 88
    • 47749145709 scopus 로고    scopus 로고
    • Cocaine but not natural reward self-administration nor passive cocaine infusion produces persistent LTP in the VTA
    • Chen, B. T.; Bowers, M. S.; Martin, M.; Hopf, F. W.; Guillory, A. M.; Carelli, R. M.; Chou, J. K.; Bonci, A. Cocaine but not natural reward self-administration nor passive cocaine infusion produces persistent LTP in the VTA. Neuron 2008, 59, 288-297.
    • (2008) Neuron , vol.59 , pp. 288-297
    • Chen, B.T.1    Bowers, M.S.2    Martin, M.3    Hopf, F.W.4    Guillory, A.M.5    Carelli, R.M.6    Chou, J.K.7    Bonci, A.8
  • 89
    • 0032953647 scopus 로고    scopus 로고
    • Neuroadaptations in ionotropic and metabotropic glutamate receptor mRNA produced by cocaine treatment
    • Ghasemzadeh, M. B.; Nelson, L. C.; Lu, X.-Y.; Kalivas, P. W. Neuroadaptations in ionotropic and metabotropic glutamate receptor mRNA produced by cocaine treatment. J. Neurochem. 1999, 72, 157-165.
    • (1999) J. Neurochem , vol.72 , pp. 157-165
    • Ghasemzadeh, M.B.1    Nelson, L.C.2    Lu, X.-Y.3    Kalivas, P.W.4
  • 91
    • 33645025726 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking
    • Backstrom, P.; Hyytia, P. Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking. Neuropsychopharmacol. 2006, 31, 778-786.
    • (2006) Neuropsychopharmacol , vol.31 , pp. 778-786
    • Backstrom, P.1    Hyytia, P.2
  • 92
    • 32344445040 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationships of 3- (2-methyl-1,3-thiazol-4- yl)ethynyl pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; Search for cocaine medications
    • Iso, Y.; Grajkowska, E.; Wroblewski, J. T.; Davis, J.; Goeders, N. E.; Johnson, K. M.; Sanker, S.; Roth, B. L.; Tueckmantel, W.; Kozikowski, A. P. Synthesis and structure-activity relationships of 3- (2-methyl-1,3-thiazol-4- yl)ethynyl pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; Search for cocaine medications. J. Med. Chem. 2006, 49, 1080-1100.
    • (2006) J. Med. Chem , vol.49 , pp. 1080-1100
    • Iso, Y.1    Grajkowska, E.2    Wroblewski, J.T.3    Davis, J.4    Goeders, N.E.5    Johnson, K.M.6    Sanker, S.7    Roth, B.L.8    Tueckmantel, W.9    Kozikowski, A.P.10
  • 93
    • 14344261021 scopus 로고    scopus 로고
    • Attenuation of behavioral effects of cocaine by the metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)-pyridine in squirrel monkeys: Comparison with dizocilpine
    • Lee, B.; Platt, D. M.; Rowlett, J. K.; Adewale, A. S.; Spealman, R. D. Attenuation of behavioral effects of cocaine by the metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)-pyridine in squirrel monkeys: comparison with dizocilpine. J. Pharmacol. Exp. Ther. 2005, 312, 1232-1240.
    • (2005) J. Pharmacol. Exp. Ther , vol.312 , pp. 1232-1240
    • Lee, B.1    Platt, D.M.2    Rowlett, J.K.3    Adewale, A.S.4    Spealman, R.D.5
  • 94
    • 0141481987 scopus 로고    scopus 로고
    • Homer1 proteins and AMPA receptors modulate cocaine-induced behavioural plasticity
    • Ghasemzadeh, M. B.; Permenter, L. K.; Lake, R.; Worley, P. F.; Kalivas, P. W. Homer1 proteins and AMPA receptors modulate cocaine-induced behavioural plasticity. Eur. J. Neurosci. 2003, 18, 1645-1651.
    • (2003) Eur. J. Neurosci , vol.18 , pp. 1645-1651
    • Ghasemzadeh, M.B.1    Permenter, L.K.2    Lake, R.3    Worley, P.F.4    Kalivas, P.W.5
  • 96
    • 36349030361 scopus 로고    scopus 로고
    • Regional differences in the effects of withdrawal from repeated cocaine upon Homer and glutamate receptor expression: A two-species comparison
    • Ary, A. W.; Szumlinski, K. K. Regional differences in the effects of withdrawal from repeated cocaine upon Homer and glutamate receptor expression: A two-species comparison. Brain Res. 2007, 1184, 295-305.
    • (2007) Brain Res , vol.1184 , pp. 295-305
    • Ary, A.W.1    Szumlinski, K.K.2
  • 97
    • 8844238423 scopus 로고    scopus 로고
    • Effects of MPEP on locomotion, sensitization and conditioned reward induced by cocaine or morphine
    • Herzig, V.; Schmidt, W. J. Effects of MPEP on locomotion, sensitization and conditioned reward induced by cocaine or morphine. Neuropharmacology 2004, 47, 973-984.
    • (2004) Neuropharmacology , vol.47 , pp. 973-984
    • Herzig, V.1    Schmidt, W.J.2
  • 98
    • 0037337238 scopus 로고    scopus 로고
    • The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse
    • McGeehan, A. J.; Olive, M. F. The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse. Synapse 2003, 47, 240-242.
    • (2003) Synapse , vol.47 , pp. 240-242
    • McGeehan, A.J.1    Olive, M.F.2
  • 99
    • 33746867592 scopus 로고    scopus 로고
    • Effects of group I metabotropic glutamate receptor antagonists on the behavioral sensitization to motor effects of cocaine in rats
    • Dravolina, O. A.; Danysz, W.; Bespalov, A. Y. Effects of group I metabotropic glutamate receptor antagonists on the behavioral sensitization to motor effects of cocaine in rats. Psychopharmacology 2006, 187, 397-404.
    • (2006) Psychopharmacology , vol.187 , pp. 397-404
    • Dravolina, O.A.1    Danysz, W.2    Bespalov, A.Y.3
  • 100
    • 0345830608 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats
    • Kenny, P. J.; Paterson, N. E.; Boutrel, B.; Semenova, S.; Harrison, A.; Gasparini, F.; Koob, G. F.; Skoubis, P. D.; Markou, A. Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats. Ann. N. Y. Acad. Sci. 2003, 1003, 415-418.
    • (2003) Ann. N. Y. Acad. Sci , vol.1003 , pp. 415-418
    • Kenny, P.J.1    Paterson, N.E.2    Boutrel, B.3    Semenova, S.4    Harrison, A.5    Gasparini, F.6    Koob, G.F.7    Skoubis, P.D.8    Markou, A.9
  • 101
    • 17744383991 scopus 로고    scopus 로고
    • The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats
    • Paterson, N. E.; Markou, A. The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats. Psychopharmacology 2005, 179, 255-261.
    • (2005) Psychopharmacology , vol.179 , pp. 255-261
    • Paterson, N.E.1    Markou, A.2
  • 102
    • 17744400697 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor blockade may attenuate cocaine self- administration by decreasing brain reward function in rats
    • Kenny, P. J.; Boutrel, B.; Gasparini, F.; Koob, G. F.; Markou, A. Metabotropic glutamate 5 receptor blockade may attenuate cocaine self- administration by decreasing brain reward function in rats. Psychopharmacology 2005, 179, 247-54.
    • (2005) Psychopharmacology , vol.179 , pp. 247-254
    • Kenny, P.J.1    Boutrel, B.2    Gasparini, F.3    Koob, G.F.4    Markou, A.5
  • 103
    • 1542358742 scopus 로고    scopus 로고
    • mGluR5-dependent increases in immediate early gene expression in the rat striatum following acute administration of amphetamine
    • Parelkar, N. K.; Wang, J. Q. mGluR5-dependent increases in immediate early gene expression in the rat striatum following acute administration of amphetamine. Mol. Brain Res. 2004, 122, 151-157.
    • (2004) Mol. Brain Res , vol.122 , pp. 151-157
    • Parelkar, N.K.1    Wang, J.Q.2
  • 104
    • 0036789802 scopus 로고    scopus 로고
    • Amphetamine increases phosphorylation of extracellular signal-regulated kinase and transcription factors in the rat striatum via group I metabotropic glutamate receptors
    • Choe, E. S.; Chung, K. T.; Mao, L. M.; Wang, J. Q. Amphetamine increases phosphorylation of extracellular signal-regulated kinase and transcription factors in the rat striatum via group I metabotropic glutamate receptors. Neuropsychopharmacol. 2002, 27, 565-575.
    • (2002) Neuropsychopharmacol , vol.27 , pp. 565-575
    • Choe, E.S.1    Chung, K.T.2    Mao, L.M.3    Wang, J.Q.4
  • 105
    • 0037063722 scopus 로고    scopus 로고
    • Regulation of transcription factor phosphorylation by metabotropic glutamate receptor-associated signaling pathways in rat striatal neurons
    • Choe, E. S.; Wang, J. Q. Regulation of transcription factor phosphorylation by metabotropic glutamate receptor-associated signaling pathways in rat striatal neurons. Neuroscience 2002, 114, 557-565.
    • (2002) Neuroscience , vol.114 , pp. 557-565
    • Choe, E.S.1    Wang, J.Q.2
  • 106
    • 4844225812 scopus 로고    scopus 로고
    • Opposite influence of MPEP, an mGluR5 antagonist, on the locomotor hyperactivity induced by PCP and amphetamine
    • Pietraszek, M.; Rogoz, Z.; Wolfarth, S.; Ossowska, K. Opposite influence of MPEP, an mGluR5 antagonist, on the locomotor hyperactivity induced by PCP and amphetamine. J. Physiol. Pharmacol., 2004, 55, 587-593.
    • (2004) J. Physiol. Pharmacol , vol.55 , pp. 587-593
    • Pietraszek, M.1    Rogoz, Z.2    Wolfarth, S.3    Ossowska, K.4
  • 107
    • 17744372482 scopus 로고    scopus 로고
    • Behavioral sensitization due to social defeat stress in mice: Antagonism at mGluR5 and NMDA receptors
    • Yap, J. J.; Covington, H. E.; Gale, M. C.; Datta, R.; Miczek, K. A. Behavioral sensitization due to social defeat stress in mice: antagonism at mGluR5 and NMDA receptors. Psychopharmacology 2005, 179, 230-239.
    • (2005) Psychopharmacology , vol.179 , pp. 230-239
    • Yap, J.J.1    Covington, H.E.2    Gale, M.C.3    Datta, R.4    Miczek, K.A.5
  • 108
    • 0035959976 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons
    • Pisani, A.; Gubellini, P.; Bonsi, P.; Conquet, F.; Picconi, B.; Centonze, D.; Bernardi, G.; Calabresi, P. Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons. Neuroscience 2001, 106, 579-587.
    • (2001) Neuroscience , vol.106 , pp. 579-587
    • Pisani, A.1    Gubellini, P.2    Bonsi, P.3    Conquet, F.4    Picconi, B.5    Centonze, D.6    Bernardi, G.7    Calabresi, P.8
  • 109
    • 0035452359 scopus 로고    scopus 로고
    • Differentially altered mGluR1 and mGluR5 mRNA expression in rat caudate nucleus and nucleus accumbens in the development and expression of behavioral sensitization to repeated amphetamine administration
    • Mao, L. M.; Wang, J. Q. Differentially altered mGluR1 and mGluR5 mRNA expression in rat caudate nucleus and nucleus accumbens in the development and expression of behavioral sensitization to repeated amphetamine administration. Synapse 2001, 41, 230-240.
    • (2001) Synapse , vol.41 , pp. 230-240
    • Mao, L.M.1    Wang, J.Q.2
  • 110
    • 0023265754 scopus 로고
    • Cocaine receptors on dopamine transporters are related to self-administration of cocaine
    • Ritz, M. C.; Lamb, R. J.; Goldberg, S. R.; Kuhar, M. J. Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 1987, 237, 1219-1223.
    • (1987) Science , vol.237 , pp. 1219-1223
    • Ritz, M.C.1    Lamb, R.J.2    Goldberg, S.R.3    Kuhar, M.J.4
  • 111
    • 0034455906 scopus 로고    scopus 로고
    • Effect of amphetamine on the expression of the metabotropic glutamate receptor 5 mRNA in developing rat brain
    • Yu, M. F.; Fu, W. M.; Yin, H. S. Effect of amphetamine on the expression of the metabotropic glutamate receptor 5 mRNA in developing rat brain. J. Mol. Neurosci. 2000, 15, 177-188.
    • (2000) J. Mol. Neurosci , vol.15 , pp. 177-188
    • Yu, M.F.1    Fu, W.M.2    Yin, H.S.3
  • 112
    • 0034813757 scopus 로고    scopus 로고
    • Amphetamine induces differential changes in the gene expression of metabotropic glutamate receptor 5 in cultured cortical and hippocampal neurons
    • Yu, M. F.; Lin, T. Y.; Ho, W. H.; Yin, H. S. Amphetamine induces differential changes in the gene expression of metabotropic glutamate receptor 5 in cultured cortical and hippocampal neurons. J. Mol. Neurosci., 2001, 17, 13-24.
    • (2001) J. Mol. Neurosci , vol.17 , pp. 13-24
    • Yu, M.F.1    Lin, T.Y.2    Ho, W.H.3    Yin, H.S.4
  • 113
    • 0242653796 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor 5 is associated with effect of amphetamine on brain neurons
    • Yu, M. F.; Lin, W. W.; Li, L. T.; Yin, H. S. Activation of metabotropic glutamate receptor 5 is associated with effect of amphetamine on brain neurons. Synapse 2003, 50, 334-344.
    • (2003) Synapse , vol.50 , pp. 334-344
    • Yu, M.F.1    Lin, W.W.2    Li, L.T.3    Yin, H.S.4
  • 114
    • 35548970758 scopus 로고    scopus 로고
    • Regulator of g-protein signaling 4 interacts with metabotropic glutamate receptor subtype 5 in rat striatum: Relevance to amphetamine Behavioral Sensitization
    • Schwendt, M.; McGinty, J. F. Regulator of g-protein signaling 4 interacts with metabotropic glutamate receptor subtype 5 in rat striatum: relevance to amphetamine Behavioral Sensitization. J. Pharmacol. Exp. Ther. 2007, 323, 650-657.
    • (2007) J. Pharmacol. Exp. Ther , vol.323 , pp. 650-657
    • Schwendt, M.1    McGinty, J.F.2
  • 115
    • 0035817763 scopus 로고    scopus 로고
    • Augmented motor activity and reduced striatal preprodynorphin mRNA induction in response to acute amphetamine administration in metabotropic glutamate receptor 1 knockout mice
    • Mao, L.; Conquet, F.; Wang, J. Q. Augmented motor activity and reduced striatal preprodynorphin mRNA induction in response to acute amphetamine administration in metabotropic glutamate receptor 1 knockout mice. Neuroscience, 2001, 106, 303-312.
    • (2001) NeuroScience , vol.106 , pp. 303-312
    • Mao, L.1    Conquet, F.2    Wang, J.Q.3
  • 116
    • 33748968301 scopus 로고    scopus 로고
    • Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: Potential insight into their antiaddictive properties
    • Lominac, K. D.; Kapasova, Z.; Hannun, R. A.; Patterson, C.; Middaugh, L. D.; Szumlinski, K. K. Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: Potential insight into their antiaddictive properties. Drug Alcohol Depend. 2006, 85, 142-156.
    • (2006) Drug Alcohol Depend , vol.85 , pp. 142-156
    • Lominac, K.D.1    Kapasova, Z.2    Hannun, R.A.3    Patterson, C.4    Middaugh, L.D.5    Szumlinski, K.K.6
  • 118
    • 0034475031 scopus 로고    scopus 로고
    • Ethanol and NMDA receptor signaling
    • Woodward, J. J. Ethanol and NMDA receptor signaling. Crit. Rev. Neurobiol. 2000, 14, 69-89.
    • (2000) Crit. Rev. Neurobiol , vol.14 , pp. 69-89
    • Woodward, J.J.1
  • 120
    • 42049098607 scopus 로고    scopus 로고
    • Accumbens Homer2 overexpression facilitates alcohol-induced neuroplasticity in C57BL/6J mice
    • Szumlinski, K. K.; Ary, A. W.; Lominac, K. D.; Klugmann, M.; Kippin, T. E. Accumbens Homer2 overexpression facilitates alcohol-induced neuroplasticity in C57BL/6J mice. Neuropsychopharmacol. 2008, 33, 1365-1378.
    • (2008) Neuropsychopharmacol , vol.33 , pp. 1365-1378
    • Szumlinski, K.K.1    Ary, A.W.2    Lominac, K.D.3    Klugmann, M.4    Kippin, T.E.5
  • 121
    • 0029831544 scopus 로고    scopus 로고
    • Chronic ethanol on mRNA levels of IP(3)R1, IP3 3-kinase and mGluR1 in mouse Purkinje neurons
    • Simonyi, A.; Zhang, J. P.; Sun, A. Y.; Sun, G. Y. Chronic ethanol on mRNA levels of IP(3)R1, IP3 3-kinase and mGluR1 in mouse Purkinje neurons. Neuroreport 1996, 7, 2115-2118.
    • (1996) Neuroreport , vol.7 , pp. 2115-2118
    • Simonyi, A.1    Zhang, J.P.2    Sun, A.Y.3    Sun, G.Y.4
  • 122
    • 4544234921 scopus 로고    scopus 로고
    • Chronic ethanol-induced subtype- and subregion-specific decrease in the mRNA expression of metabotropic glutamate receptors in rat hippocampus
    • Simonyi, A.; Christian, M. R.; Sun, A. Y.; Sun, G. Y. Chronic ethanol-induced subtype- and subregion-specific decrease in the mRNA expression of metabotropic glutamate receptors in rat hippocampus. Alcohol. Clin. Exp. Res. 2004, 28, 1419-1423.
    • (2004) Alcohol. Clin. Exp. Res , vol.28 , pp. 1419-1423
    • Simonyi, A.1    Christian, M.R.2    Sun, A.Y.3    Sun, G.Y.4
  • 124
    • 21844443847 scopus 로고    scopus 로고
    • Protein kinase C phosphorylation of the metabotropic glutamate receptor mGluR5 on serine 839 regulates Ca2+ oscillations
    • Kim, C. H.; Braud, S.; Isaac, J. T. R.; Roche, K. W. Protein kinase C phosphorylation of the metabotropic glutamate receptor mGluR5 on serine 839 regulates Ca2+ oscillations. J. Biol. Chem. 2005, 280, 25409-25415.
    • (2005) J. Biol. Chem , vol.280 , pp. 25409-25415
    • Kim, C.H.1    Braud, S.2    Isaac, J.T.R.3    Roche, K.W.4
  • 125
    • 0029113136 scopus 로고
    • Modulatory effects of acute ethanol on metabotropic glutamate responses in cultured purkinje neurons
    • Netzeband, J. G.; Gruol, D. L. Modulatory effects of acute ethanol on metabotropic glutamate responses in cultured purkinje neurons. Brain Res. 1995, 688, 105-113.
    • (1995) Brain Res , vol.688 , pp. 105-113
    • Netzeband, J.G.1    Gruol, D.L.2
  • 126
    • 0031915098 scopus 로고    scopus 로고
    • Effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus laevis oocytes
    • Minami, K.; Gereau, R. W.; Minami, M.; Heinemann, S. F.; Harris, R. A. Effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus laevis oocytes. Mol. Pharmacol. 1998, 53, 148-156.
    • (1998) Mol. Pharmacol , vol.53 , pp. 148-156
    • Minami, K.1    Gereau, R.W.2    Minami, M.3    Heinemann, S.F.4    Harris, R.A.5
  • 127
    • 0036209061 scopus 로고    scopus 로고
    • Ethanol alters glutamate but not adenosine uptake in rat astrocytes: Evidence for protein kinase C involvement
    • Othman, T.; Sinclair, C. J. D.; Haughey, N.; Geiger, J. D.; Parkinson, F. E. Ethanol alters glutamate but not adenosine uptake in rat astrocytes: Evidence for protein kinase C involvement. Neurochem. Res. 2002, 27, 289-296.
    • (2002) Neurochem. Res , vol.27 , pp. 289-296
    • Othman, T.1    Sinclair, C.J.D.2    Haughey, N.3    Geiger, J.D.4    Parkinson, F.E.5
  • 128
    • 0037111866 scopus 로고    scopus 로고
    • Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice
    • Choi, D.-S.; Wang, D.; Dadgar, J.; Chang, W. S.; Messing, R. O. Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice. J. Neurosci. 2002, 22, 9905-9911.
    • (2002) J. Neurosci , vol.22 , pp. 9905-9911
    • Choi, D.-S.1    Wang, D.2    Dadgar, J.3    Chang, W.S.4    Messing, R.O.5
  • 130
  • 131
    • 37349093371 scopus 로고    scopus 로고
    • Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice
    • Sharko, A. C.; Hodge, C. W. Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice. Alcohol. Clin. Exp. Res. 2008, 32, 67-76.
    • (2008) Alcohol. Clin. Exp. Res , vol.32 , pp. 67-76
    • Sharko, A.C.1    Hodge, C.W.2
  • 132
    • 13444291828 scopus 로고    scopus 로고
    • The mGluR5 antagonist 6-methyl-2- (phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism
    • Olive, M. F.; McGeehan, A. J.; Kinder, J. R.; McMahon, T.; Hodge, C. W.; Janak, P. H.; Messing, R. O. The mGluR5 antagonist 6-methyl-2- (phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism. Mol. Pharmacol. 2005, 67, 349-355.
    • (2005) Mol. Pharmacol , vol.67 , pp. 349-355
    • Olive, M.F.1    McGeehan, A.J.2    Kinder, J.R.3    McMahon, T.4    Hodge, C.W.5    Janak, P.H.6    Messing, R.O.7
  • 133
    • 33750733892 scopus 로고    scopus 로고
    • Involvement of mGluR5 in the ethanol-induced neuropathic pain-like state in the rat
    • Miyoshi, K.; Narita, M.; Suzuki, T. Involvement of mGluR5 in the ethanol-induced neuropathic pain-like state in the rat. Neurosci. Lett. 2006, 410, 105-109.
    • (2006) Neurosci. Lett , vol.410 , pp. 105-109
    • Miyoshi, K.1    Narita, M.2    Suzuki, T.3
  • 134
    • 34147161303 scopus 로고    scopus 로고
    • mGlu5 receptor and protein kinase C implicated in the development and induction of neuropathic pain following chronic ethanol consumption
    • Miyoshi, K.; Narita, M.; Takatsu, M.; Suzuki, T. mGlu5 receptor and protein kinase C implicated in the development and induction of neuropathic pain following chronic ethanol consumption. Eur. J. Pharmacol. 2007, 562, 208-211.
    • (2007) Eur. J. Pharmacol , vol.562 , pp. 208-211
    • Miyoshi, K.1    Narita, M.2    Takatsu, M.3    Suzuki, T.4
  • 135
    • 30344434000 scopus 로고    scopus 로고
    • N-methyl-D-aspartate and group I metabotropic glutamate receptors are involved in the expression of ethanolinduced sensitization in mice
    • Kotlinska, J.; Bochenski, M.; Danysz, W. N-methyl-D-aspartate and group I metabotropic glutamate receptors are involved in the expression of ethanolinduced sensitization in mice. Behav. Pharmacol. 2006, 17, 1-8.
    • (2006) Behav. Pharmacol , vol.17 , pp. 1-8
    • Kotlinska, J.1    Bochenski, M.2    Danysz, W.3
  • 136
    • 38349105319 scopus 로고    scopus 로고
    • Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats
    • Besheer, J.; Faccidomo, S.; Grondin, J. J. M.; Hodge, C. W. Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats. Alcohol. Clin. Exp. Res. 2008, 32, 209-221.
    • (2008) Alcohol. Clin. Exp. Res , vol.32 , pp. 209-221
    • Besheer, J.1    Faccidomo, S.2    Grondin, J.J.M.3    Hodge, C.W.4
  • 137
    • 10744224826 scopus 로고    scopus 로고
    • The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors
    • Harris, B. R.; Gibson, D. A.; Prendergast, M. A.; Blanchard, J. A.; Holley, R. C.; Hart, S. R.; Scotland, R. L.; Foster, T. C.; Pedigo, N. W.; Littleton, J. M. The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors. Alcohol. Clin. Exp. Res. 2003, 27, 1724-1735.
    • (2003) Alcohol. Clin. Exp. Res , vol.27 , pp. 1724-1735
    • Harris, B.R.1    Gibson, D.A.2    Prendergast, M.A.3    Blanchard, J.A.4    Holley, R.C.5    Hart, S.R.6    Scotland, R.L.7    Foster, T.C.8    Pedigo, N.W.9    Littleton, J.M.10
  • 139
    • 0029119866 scopus 로고
    • Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum
    • Rossetti, Z. L.; Carboni, S. Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum. Eur. J. Pharmacol. 1995, 283, 177-183.
    • (1995) Eur. J. Pharmacol , vol.283 , pp. 177-183
    • Rossetti, Z.L.1    Carboni, S.2
  • 140
    • 23044516183 scopus 로고    scopus 로고
    • Neuroprotective and abstinence-promoting effects of acamprosate - Elucidating the mechanism of action
    • De Witte, P.; Littleton, J.; Parot, P.; Koob, G. Neuroprotective and abstinence-promoting effects of acamprosate - Elucidating the mechanism of action. CNS Drugs 2005, 19, 517-537.
    • (2005) CNS Drugs , vol.19 , pp. 517-537
    • de Witte, P.1    Littleton, J.2    Parot, P.3    Koob, G.4
  • 141
    • 27144492737 scopus 로고    scopus 로고
    • The metabotropic glutamate 5 receptor antagonist 3- [(2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine reduces ethanol self-administration in multiple strains of alcohol-preferring rats and regulates olfactory glutamatergic systems
    • Cowen, M. S.; Djouma, E.; Lawrence, A. J. The metabotropic glutamate 5 receptor antagonist 3- [(2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine reduces ethanol self-administration in multiple strains of alcohol-preferring rats and regulates olfactory glutamatergic systems. J. Pharmacol. Exp. Ther. 2005, 315, 1-11.
    • (2005) J. Pharmacol. Exp. Ther , vol.315 , pp. 1-11
    • Cowen, M.S.1    Djouma, E.2    Lawrence, A.J.3
  • 142
    • 27744477334 scopus 로고    scopus 로고
    • Effects of a metabotropic, mGlu5, glutamate receptor antagonist on ethanol consumption by genetic drinking rats
    • McMillen, B. A.; Crawford, M. S.; Kulers, C. M.; Williams, H. L. Effects of a metabotropic, mGlu5, glutamate receptor antagonist on ethanol consumption by genetic drinking rats. Alcohol Alcoholism 2005, 40, 494-497.
    • (2005) Alcohol Alcoholism , vol.40 , pp. 494-497
    • McMillen, B.A.1    Crawford, M.S.2    Kulers, C.M.3    Williams, H.L.4
  • 143
    • 17744365745 scopus 로고    scopus 로고
    • The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats
    • Schroeder, J. P.; Overstreet, D. H.; Hodge, C. W. The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats. Psychopharmacology 2005, 179, 262-270.
    • (2005) Psychopharmacology , vol.179 , pp. 262-270
    • Schroeder, J.P.1    Overstreet, D.H.2    Hodge, C.W.3
  • 145
    • 33845368429 scopus 로고    scopus 로고
    • Assessing appetitive and consummatory phases of ethanol self-administration in C57BL/6J mice under operant conditions: Regulation by mGlu5 receptor antagonism
    • Cowen, M. S.; Krstew, E.; Lawrence, A. J. Assessing appetitive and consummatory phases of ethanol self-administration in C57BL/6J mice under operant conditions: regulation by mGlu5 receptor antagonism. Psychopharmacology 2007, 190, 21-29.
    • (2007) Psychopharmacology , vol.190 , pp. 21-29
    • Cowen, M.S.1    Krstew, E.2    Lawrence, A.J.3
  • 147
    • 38749110355 scopus 로고    scopus 로고
    • Effects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats
    • Besheer, J.; Faccidomo, S.; Grondin, J. J. M.; Hodge, C. W. Effects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats. Alcohol 2008, 42, 13-20.
    • (2008) Alcohol , vol.42 , pp. 13-20
    • Besheer, J.1    Faccidomo, S.2    Grondin, J.J.M.3    Hodge, C.W.4
  • 148
    • 0032874391 scopus 로고    scopus 로고
    • Potentiation of NMDA and AMPA responses by the specific mGluR(5) agonist CHPG in spinal cord motoneurons
    • Ugolini, A.; Corsi, M.; Bordi, F. Potentiation of NMDA and AMPA responses by the specific mGluR(5) agonist CHPG in spinal cord motoneurons. Neuropharmacology 1999, 38, 1569-1576.
    • (1999) Neuropharmacology , vol.38 , pp. 1569-1576
    • Ugolini, A.1    Corsi, M.2    Bordi, F.3
  • 149
    • 32544453979 scopus 로고    scopus 로고
    • Long-term depression of NMDA receptor-mediated synaptic transmission is dependent on activation of metabotropic glutamate receptors and is altered to long-term potentiation by low intracellular calcium buffering
    • Harney, S. C.; Rowan, M.; Anwyl, R. Long-term depression of NMDA receptor-mediated synaptic transmission is dependent on activation of metabotropic glutamate receptors and is altered to long-term potentiation by low intracellular calcium buffering. J. Neurosci. 2006, 26, 1128-1132.
    • (2006) J. Neurosci , vol.26 , pp. 1128-1132
    • Harney, S.C.1    Rowan, M.2    Anwyl, R.3
  • 151
    • 0031981194 scopus 로고    scopus 로고
    • Chronic ethanol exposure impairs phosphorylation of CREB and CRE-binding activity in rat striatum
    • Yang, X. O.; Horn, K.; Wand, G. S. Chronic ethanol exposure impairs phosphorylation of CREB and CRE-binding activity in rat striatum. Alcohol. Clin. Exp. Res. 1998, 22, 382-390.
    • (1998) Alcohol. Clin. Exp. Res , vol.22 , pp. 382-390
    • Yang, X.O.1    Horn, K.2    Wand, G.S.3
  • 153
    • 2942650911 scopus 로고    scopus 로고
    • Functional interaction between NMDA and mGlu5 receptors: Effects on working memory, instrumental learning, motor behaviors, and dopamine release
    • Homayoun, H.; Stefani, M. R.; Adams, B. W.; Tamagan, G. D.; Moghaddam, B. Functional interaction between NMDA and mGlu5 receptors: Effects on working memory, instrumental learning, motor behaviors, and dopamine release. Neuropsychopharmacol. 2004, 29, 1259-1269.
    • (2004) Neuropsychopharmacol , vol.29 , pp. 1259-1269
    • Homayoun, H.1    Stefani, M.R.2    Adams, B.W.3    Tamagan, G.D.4    Moghaddam, B.5
  • 154
    • 0000068515 scopus 로고
    • Biphasic Action of Ethanol
    • Pohorecky, L. A. Biphasic Action of Ethanol. Biobehavioral Rev. 1977, 1, 231-240.
    • (1977) Biobehavioral Rev , vol.1 , pp. 231-240
    • Pohorecky, L.A.1
  • 156
    • 15444362811 scopus 로고    scopus 로고
    • Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha 1-containing receptors in the discriminative stimulus effects of ethanol
    • Besheer, J.; Hodge, C. W. Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha 1-containing receptors in the discriminative stimulus effects of ethanol. Neuropsychopharmacol. 2005, 30, 747-757.
    • (2005) Neuropsychopharmacol , vol.30 , pp. 747-757
    • Besheer, J.1    Hodge, C.W.2
  • 157
    • 0034626632 scopus 로고    scopus 로고
    • The mGlu(5) receptor agonist CHPG stimulates striatal glutamate release: Possible involvement of A(2A) receptors
    • Pintor, A.; Pezzola, A.; Reggio, R.; Quarta, D.; Popoli, P. The mGlu(5) receptor agonist CHPG stimulates striatal glutamate release: possible involvement of A(2A) receptors. Neuroreport 2000, 11, 3611-3614.
    • (2000) Neuroreport , vol.11 , pp. 3611-3614
    • Pintor, A.1    Pezzola, A.2    Reggio, R.3    Quarta, D.4    Popoli, P.5
  • 159
    • 13244264871 scopus 로고    scopus 로고
    • Colocalization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum
    • Rodrigues, R. J.; Alfaro, T. M.; Rebola, N.; Oliveira, C. R.; Cunha, R. A. Colocalization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum. J. Neurochem. 2005, 92, 433-441.
    • (2005) J. Neurochem , vol.92 , pp. 433-441
    • Rodrigues, R.J.1    Alfaro, T.M.2    Rebola, N.3    Oliveira, C.R.4    Cunha, R.A.5
  • 160
    • 27744450594 scopus 로고    scopus 로고
    • Interactions between metabotropic glutamate 5 and adenosine A(2A) receptors in normal and parkinsonian mice
    • Kachroo, A.; Orlando, L. R.; Grandy, D. K.; Chen, J. F.; Young, A. B.; Schwarzschild, M. A. Interactions between metabotropic glutamate 5 and adenosine A(2A) receptors in normal and parkinsonian mice. J. Neurosci. 2005, 25, 10414-10419.
    • (2005) J. Neurosci , vol.25 , pp. 10414-10419
    • Kachroo, A.1    Orlando, L.R.2    Grandy, D.K.3    Chen, J.F.4    Young, A.B.5    Schwarzschild, M.A.6
  • 161
    • 3242765264 scopus 로고    scopus 로고
    • Simultaneous blockade of adenosine A(2A) and metabotropic glutamate mGlu(5) receptors increase their efficacy in reversing parkinsonian deficits in rats
    • Coccurello, R.; Breysse, N.; Amalric, M. Simultaneous blockade of adenosine A(2A) and metabotropic glutamate mGlu(5) receptors increase their efficacy in reversing parkinsonian deficits in rats. Neuropsychopharmacol. 2004, 29, 1451-1461.
    • (2004) Neuropsychopharmacol , vol.29 , pp. 1451-1461
    • Coccurello, R.1    Breysse, N.2    Amalric, M.3
  • 162
    • 4544339812 scopus 로고    scopus 로고
    • Ethanol operant self-administration in rats is regulated by adenosine A(2) receptors
    • Arolfo, M. P.; Yao, L.; Gordon, A. S.; Diamond, I.; Janak, P. H. Ethanol operant self-administration in rats is regulated by adenosine A(2) receptors. Alcohol. Clin. Exp. Res. 2004, 28, 1308-1316.
    • (2004) Alcohol. Clin. Exp. Res , vol.28 , pp. 1308-1316
    • Arolfo, M.P.1    Yao, L.2    Gordon, A.S.3    Diamond, I.4    Janak, P.H.5
  • 163
    • 38949186761 scopus 로고    scopus 로고
    • Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats
    • Adams, C. L.; Cowen, M. S.; Short, J. L.; Lawrence, A. J. Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats. Int. J. Neuropsychopharmacol. 2008, 11, 229-241.
    • (2008) Int. J. Neuropsychopharmacol , vol.11 , pp. 229-241
    • Adams, C.L.1    Cowen, M.S.2    Short, J.L.3    Lawrence, A.J.4
  • 164
    • 17144428515 scopus 로고    scopus 로고
    • Regulation of Homer and group I metabotropic glutamate receptors by nicotine
    • Kane, J. K.; Hwang, Y.; Konu, O.; Loughlin, S. E.; Leslie, F. M.; Li, M. D. Regulation of Homer and group I metabotropic glutamate receptors by nicotine. Eur. J. Neurosci. 2005, 21, 1145-1154.
    • (2005) Eur. J. Neurosci , vol.21 , pp. 1145-1154
    • Kane, J.K.1    Hwang, Y.2    Konu, O.3    Loughlin, S.E.4    Leslie, F.M.5    Li, M.D.6
  • 165
    • 0036181180 scopus 로고    scopus 로고
    • Nicotine potentiation of brain stimulation reward reversed by DH beta E and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats
    • Harrison, A. A.; Gasparini, F.; Markou, A. Nicotine potentiation of brain stimulation reward reversed by DH beta E and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats. Psychopharmacology 2002, 160, 56-66.
    • (2002) Psychopharmacology , vol.160 , pp. 56-66
    • Harrison, A.A.1    Gasparini, F.2    Markou, A.3
  • 166
    • 33845676294 scopus 로고    scopus 로고
    • Nicotinic receptor-mediated enhancement of long-term potentiation involves activation of metabotropic glutamate receptors and ryanodine-sensitive calcium stores in the dentate gyrus
    • Welsby, P.; Rowan, M.; Anwyl, R. Nicotinic receptor-mediated enhancement of long-term potentiation involves activation of metabotropic glutamate receptors and ryanodine-sensitive calcium stores in the dentate gyrus. Eur. J. Neurosci. 2006, 24, 3109-3118.
    • (2006) Eur. J. Neurosci , vol.24 , pp. 3109-3118
    • Welsby, P.1    Rowan, M.2    Anwyl, R.3
  • 167
    • 29244446775 scopus 로고    scopus 로고
    • Nicotine has a permissive role on the activation of metabotropic glutamate 5 receptors coexisting with nicotinic receptors on rat hippocampal noradrenergic nerve terminals
    • Parodi, M.; Patti, L.; Grilli, M.; Raiteri, M.; Marchi, M. Nicotine has a permissive role on the activation of metabotropic glutamate 5 receptors coexisting with nicotinic receptors on rat hippocampal noradrenergic nerve terminals. Neurochem. Int. 2006, 48, 138-143.
    • (2006) Neurochem. Int , vol.48 , pp. 138-143
    • Parodi, M.1    Patti, L.2    Grilli, M.3    Raiteri, M.4    Marchi, M.5
  • 168
    • 33845283874 scopus 로고    scopus 로고
    • Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats
    • Liechti, M. E.; Markou, A. Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats. Eur. J. Pharmacol. 2007, 554, 164-174.
    • (2007) Eur. J. Pharmacol , vol.554 , pp. 164-174
    • Liechti, M.E.1    Markou, A.2
  • 169
    • 0038240644 scopus 로고    scopus 로고
    • The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice
    • Paterson, N. E.; Semenova, S.; Gasparini, F.; Markou, A. The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice. Psychopharmacology 2003, 167, 257-264.
    • (2003) Psychopharmacology , vol.167 , pp. 257-264
    • Paterson, N.E.1    Semenova, S.2    Gasparini, F.3    Markou, A.4
  • 170
    • 19244387486 scopus 로고    scopus 로고
    • Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking
    • Tessari, M.; Pilla, M.; Andreoli, M.; Hutcheson, D. M.; Heidbreder, C. A. Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking. Eur. J. Pharmacol. 2004, 499, 121-133.
    • (2004) Eur. J. Pharmacol , vol.499 , pp. 121-133
    • Tessari, M.1    Pilla, M.2    Andreoli, M.3    Hutcheson, D.M.4    Heidbreder, C.A.5
  • 171
    • 23644451337 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats
    • Bespalov, A. Y.; Dravolina, O. A.; Sukhanov, I.; Zakharova, E.; Blokhina, E.; Zvartau, E.; Danysz, W.; van Heeke, G.; Markou, A. Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats. Neuropharmacology 2005, 49, 167-178.
    • (2005) Neuropharmacology , vol.49 , pp. 167-178
    • Bespalov, A.Y.1    Dravolina, O.A.2    Sukhanov, I.3    Zakharova, E.4    Blokhina, E.5    Zvartau, E.6    Danysz, W.7    van Heeke, G.8    Markou, A.9
  • 172
    • 33846292496 scopus 로고    scopus 로고
    • mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats
    • Dravolina, O. A.; Zakharova, E. S.; Shekunova, E. V.; Zvartau, E. E.; Danysz, W.; Bespalov, A. Y. mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats. Neuropharmacology 2007, 52, 263-269.
    • (2007) Neuropharmacology , vol.52 , pp. 263-269
    • Dravolina, O.A.1    Zakharova, E.S.2    Shekunova, E.V.3    Zvartau, E.E.4    Danysz, W.5    Bespalov, A.Y.6
  • 173
    • 27844469793 scopus 로고    scopus 로고
    • The motivational component of with- drawal in opiate addiction: Role of associative learning and aversive memory in opiate addiction from a behavioral, anatomical and functional perspective
    • Frenois, F.; Le Moine, C.; Cador, M. The motivational component of with- drawal in opiate addiction: Role of associative learning and aversive memory in opiate addiction from a behavioral, anatomical and functional perspective. Rev. Neurosci. 2005, 16, 255-276.
    • (2005) Rev. Neurosci , vol.16 , pp. 255-276
    • Frenois, F.1    Le Moine, C.2    Cador, M.3
  • 174
    • 13444263521 scopus 로고    scopus 로고
    • The mGlu5 receptor antagonists MPEP and MTEP attenuate behavioral signs of morphine with- drawal and morphine-withdrawal-induced activation of locus coeruleus neurons in rats
    • Rasmussen, K.; Martin, H.; Berger, J. E.; Seager, M. A. The mGlu5 receptor antagonists MPEP and MTEP attenuate behavioral signs of morphine with- drawal and morphine-withdrawal-induced activation of locus coeruleus neurons in rats. Neuropharmacology 2005, 48, 173-180.
    • (2005) Neuropharmacology , vol.48 , pp. 173-180
    • Rasmussen, K.1    Martin, H.2    Berger, J.E.3    Seager, M.A.4
  • 175
    • 33847331564 scopus 로고    scopus 로고
    • Comparison of the effects of mGluR1 and mGluR5 antagonists on the expression of behavioral sensitization to the locomotor effect of morphine and the morphine withdrawal jumping in mice
    • Kotlinska, J.; Bochenski, M. Comparison of the effects of mGluR1 and mGluR5 antagonists on the expression of behavioral sensitization to the locomotor effect of morphine and the morphine withdrawal jumping in mice. Eur. J. Pharmacol. 2007, 558, 113-118.
    • (2007) Eur. J. Pharmacol , vol.558 , pp. 113-118
    • Kotlinska, J.1    Bochenski, M.2
  • 176
    • 34249320549 scopus 로고    scopus 로고
    • Role of spinal metabotropic glutamate receptor subtype 5 in the development of tolerance to morphine-induced antinociception in rat
    • Xu, T.; Jiang, W.; Du, D. P.; Xu, Y. M.; Hu, Q.; Shen, Q. Role of spinal metabotropic glutamate receptor subtype 5 in the development of tolerance to morphine-induced antinociception in rat. Neurosci. Lett. 2007, 420, 155-159.
    • (2007) Neurosci. Lett , vol.420 , pp. 155-159
    • Xu, T.1    Jiang, W.2    Du, D.P.3    Xu, Y.M.4    Hu, Q.5    Shen, Q.6
  • 177
    • 24144487021 scopus 로고    scopus 로고
    • Involvement of spinal metabotropic glutamate receptor 5 in the development of tolerance to morphine-induced antinociception
    • Narita, M.; Suzuki, M.; Niikura, K.; Nakamura, A.; Miyatake, M.; Aoki, T.; Yajima, Y.; Suzuki, T. Involvement of spinal metabotropic glutamate receptor 5 in the development of tolerance to morphine-induced antinociception. J. Neurochem. 2005, 94, 1297-1305.
    • (2005) J. Neurochem , vol.94 , pp. 1297-1305
    • Narita, M.1    Suzuki, M.2    Niikura, K.3    Nakamura, A.4    Miyatake, M.5    Aoki, T.6    Yajima, Y.7    Suzuki, T.8
  • 178
    • 0036951025 scopus 로고    scopus 로고
    • Morphine conditioned reward is inhibited by MPEP, the mGluR5 antagonist
    • Popik, P.; Wrobel, M. Morphine conditioned reward is inhibited by MPEP, the mGluR5 antagonist. Neuropharmacology 2002, 43, 1210-1217.
    • (2002) Neuropharmacology , vol.43 , pp. 1210-1217
    • Popik, P.1    Wrobel, M.2
  • 179
    • 33748062344 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP
    • Lea, P. M.; Faden, A. I. Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP. CNS Drug Rev. 2006, 12, 149-166.
    • (2006) CNS Drug Rev , vol.12 , pp. 149-166
    • Lea, P.M.1    Faden, A.I.2
  • 180
    • 4644335722 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 localized in the limbic forebrain is critical for the development of morphine-induced rewarding effect in mice
    • Aoki, T.; Narita, M.; Shibasaki, M.; Suzuki, T. Metabotropic glutamate receptor 5 localized in the limbic forebrain is critical for the development of morphine-induced rewarding effect in mice. Eur. J. Neurosci. 2004, 20, 1633-1638.
    • (2004) Eur. J. Neurosci , vol.20 , pp. 1633-1638
    • Aoki, T.1    Narita, M.2    Shibasaki, M.3    Suzuki, T.4
  • 181
    • 35948936012 scopus 로고    scopus 로고
    • Effect of 2-methyl-6- (phenyl ethynyl) pyridine on intravenous self-administration of ketamine and heroin in the rat
    • Van der Kam, E. L.; De Vry, J.; Tzschentke, T. M. Effect of 2-methyl-6- (phenyl ethynyl) pyridine on intravenous self-administration of ketamine and heroin in the rat. Behav. Pharmacol. 2007, 18, 717-724.
    • (2007) Behav. Pharmacol , vol.18 , pp. 717-724
    • van der Kam, E.L.1    de Vry, J.2    Tzschentke, T.M.3
  • 182
    • 0025325535 scopus 로고
    • Structure of a Cannabinoid Receptor and Functional Expression of the Cloned cDNA
    • Matsuda, L. A.; Lolait, S. J.; Brownstein, M. J.; Young, A. C.; Bonner, T. I. Structure of a Cannabinoid Receptor and Functional Expression of the Cloned cDNA. Nature 1990, 346, 561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 184
    • 27544452741 scopus 로고    scopus 로고
    • Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors
    • Jung, K. M.; Mangieri, R.; Stapleton, C.; Kim, J.; Fegley, D.; Wallace, M.; Mackie, K.; Piomelli, D. Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. Mol. Pharmacol. 2005, 68, 1196-1202.
    • (2005) Mol. Pharmacol , vol.68 , pp. 1196-1202
    • Jung, K.M.1    Mangieri, R.2    Stapleton, C.3    Kim, J.4    Fegley, D.5    Wallace, M.6    Mackie, K.7    Piomelli, D.8
  • 186
    • 0037062421 scopus 로고    scopus 로고
    • Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens
    • Robbe, D.; Kopf, M.; Remaury, A.; Bockaert, J.; Manzoni, O. J. Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens. Proc. Natl. Acad. Sci. USA 2002, 99, 8384-8388.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 8384-8388
    • Robbe, D.1    Kopf, M.2    Remaury, A.3    Bockaert, J.4    Manzoni, O.J.5
  • 190
    • 0036892012 scopus 로고    scopus 로고
    • Group-I metabotropic glutamate receptors, mG1u1a and mG1u5a, couple to extracellular signal-regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways
    • Thandi, S.; Blank, J. L.; Challiss, R. A. J. Group-I metabotropic glutamate receptors, mG1u1a and mG1u5a, couple to extracellular signal-regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways. J. Neurochem. 2002, 83, 1139-1153.
    • (2002) J. Neurochem , vol.83 , pp. 1139-1153
    • Thandi, S.1    Blank, J.L.2    Challiss, R.A.J.3
  • 191
    • 0029795629 scopus 로고    scopus 로고
    • Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors
    • Kawabata, S.; Tsutsumi, R.; Kohara, A.; Yamaguchi, T.; Nakanishi, S.; Okada, M. Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors. Nature 1996, 383, 89-92.
    • (1996) Nature , vol.383 , pp. 89-92
    • Kawabata, S.1    Tsutsumi, R.2    Kohara, A.3    Yamaguchi, T.4    Nakanishi, S.5    Okada, M.6
  • 192
    • 2642520288 scopus 로고    scopus 로고
    • Effects of mGlu(1) and mGlu(5) metabotropic glutamate antagonists to reverse morphine tolerance in mice
    • Smith, F. L.; Smith, P. A.; Dewey, W. L.; Javed, R. R. Effects of mGlu(1) and mGlu(5) metabotropic glutamate antagonists to reverse morphine tolerance in mice. Eur. J. Pharmacol. 2004, 492, 137-142.
    • (2004) Eur. J. Pharmacol , vol.492 , pp. 137-142
    • Smith, F.L.1    Smith, P.A.2    Dewey, W.L.3    Javed, R.R.4
  • 193
    • 0037402026 scopus 로고    scopus 로고
    • Blockade of the locomotor stimulant effects of amphetamine by group I, group II, and group III metabotropic glutamate receptor ligands in the rat nucleus accumbens: Possible interactions with dopamine receptors
    • David, H. N.; Abraini, J. H. Blockade of the locomotor stimulant effects of amphetamine by group I, group II, and group III metabotropic glutamate receptor ligands in the rat nucleus accumbens: possible interactions with dopamine receptors. Neuropharmacology 2003, 44, 717-727.
    • (2003) Neuropharmacology , vol.44 , pp. 717-727
    • David, H.N.1    Abraini, J.H.2
  • 194
    • 3142737454 scopus 로고    scopus 로고
    • Effect of the mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine (MPEP) on the acute locomotor stimulant properties of cocaine, D-amphetamine, and the dopamine reuptake inhibitor GBR12909 in mice
    • McGeehan, A. J.; Janak, P. H.; Olive, M. F. Effect of the mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine (MPEP) on the acute locomotor stimulant properties of cocaine, D-amphetamine, and the dopamine reuptake inhibitor GBR12909 in mice. Psychopharmacology 2004, 174, 266-273.
    • (2004) Psychopharmacology , vol.174 , pp. 266-273
    • McGeehan, A.J.1    Janak, P.H.2    Olive, M.F.3
  • 195
    • 5344232797 scopus 로고    scopus 로고
    • Memory and addiction: Shared neural circuitry and molecular mechanisms
    • Kelley, A. E. Memory and addiction: shared neural circuitry and molecular mechanisms. Neuron 2004, 44, 161-179.
    • (2004) Neuron , vol.44 , pp. 161-179
    • Kelley, A.E.1
  • 196
    • 0030954048 scopus 로고    scopus 로고
    • Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP
    • Lu, Y.-M.; Jia, Z.; Janus, C.; Henderson, J. T.; Gerlai, R.; Wojtowicz, J. M.; Roder, J. C. Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. J. Neurosci. 1997, 17, 5196-5205.
    • (1997) J. Neurosci , vol.17 , pp. 5196-5205
    • Lu, Y.-M.1    Jia, Z.2    Janus, C.3    Henderson, J.T.4    Gerlai, R.5    Wojtowicz, J.M.6    Roder, J.C.7
  • 197
    • 0034820627 scopus 로고    scopus 로고
    • Gene targeting reveals a role for the glutamate receptors mGluR5 and GluR2 in learning and memory
    • Jia, Z. P.; Lu, Y. M.; Agopyan, N.; Roder, J. Gene targeting reveals a role for the glutamate receptors mGluR5 and GluR2 in learning and memory. Physiol. Behav. 2001, 73, 793-802.
    • (2001) Physiol. Behav , vol.73 , pp. 793-802
    • Jia, Z.P.1    Lu, Y.M.2    Agopyan, N.3    Roder, J.4
  • 198
    • 0035996371 scopus 로고    scopus 로고
    • Inhibition of mGluR5 blocks hippocampal UP in vivo and spatial leaming in rats
    • Balschun, D.; Wetzel, W. Inhibition of mGluR5 blocks hippocampal UP in vivo and spatial leaming in rats. Pharmacol. Biochem. Behav. 2002, 73, 375-380.
    • (2002) Pharmacol. Biochem. Behav , vol.73 , pp. 375-380
    • Balschun, D.1    Wetzel, W.2
  • 199
    • 26844466906 scopus 로고    scopus 로고
    • The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity
    • Manahan-Vaughan, D.; Braunewell, K. H. The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity. Cereb. Cortex 2005, 15, 1703-1713.
    • (2005) Cereb. Cortex , vol.15 , pp. 1703-1713
    • Manahan-Vaughan, D.1    Braunewell, K.H.2
  • 200
    • 34250349668 scopus 로고    scopus 로고
    • The role of metabotropic glutamate receptors in drug reward, motivation and dependence
    • Markou, A. The role of metabotropic glutamate receptors in drug reward, motivation and dependence. Drug News Perspect. 2007, 20, 103-108.
    • (2007) Drug News Perspect , vol.20 , pp. 103-108
    • Markou, A.1
  • 201
    • 2442672865 scopus 로고    scopus 로고
    • Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: Comparison between cocaine and a potent conventional reinforcer
    • Baptista, M. A. S.; Martin-Fardon, R.; Weiss, F. Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: Comparison between cocaine and a potent conventional reinforcer. J. Neurosci. 2004, 24, 4723-4727.
    • (2004) J. Neurosci , vol.24 , pp. 4723-4727
    • Baptista, M.A.S.1    Martin-Fardon, R.2    Weiss, F.3
  • 202
    • 21344434071 scopus 로고    scopus 로고
    • The novel mGluR(2/3) agonist LY379268 attenuates cue-induced reinstatement of heroin seeking
    • Bossert, J. M.; Busch, R. F.; Gray, S. M. The novel mGluR(2/3) agonist LY379268 attenuates cue-induced reinstatement of heroin seeking. Neuroreport 2005, 16, 1013-1016.
    • (2005) Neuroreport , vol.16 , pp. 1013-1016
    • Bossert, J.M.1    Busch, R.F.2    Gray, S.M.3


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