N-methyl-D-aspartate and group I metabotropic glutamate receptors are involved in the expression of ethanol-induced sensitization in mice

Behavioural Pharmacology

Volumn 17, Issue 1, 2006, Pages 1-8

  Kotlinska, Jolanta ^a   Bochenski, Marcin ^a   Danysz, Wojciech ^b  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b MERZ PHARMACEUTICALS GMBH   (Germany)

Author keywords

Ethanol; Locomotor activity; Metabotropic glutamatergic receptor antagonists; Mice; N methyl D aspartate antagonists; Sensitization

Indexed keywords

3 [(2 METHYL 4 THIAZOLYL)ETHYNYL]PYRIDINE; ACAMPROSATE; ALCOHOL; DIZOCILPINE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG EFFECT; MALE; MOUSE; NEUROTRANSMISSION; NONHUMAN; PROTEIN EXPRESSION;

ALCOHOLISM; ANIMALS; BRAIN; CYCLOPENTANES; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ETHANOL; GLUTAMIC ACID; MALE; MICE; MOTOR ACTIVITY; N-METHYLASPARTATE; PYRIDINES; QUINOLINES; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; STEREOTYPED BEHAVIOR; SYNAPTIC TRANSMISSION; TAURINE; THIAZOLES;

EID: 30344434000     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.fbp.0000181600.95405.c7     Document Type: Article

References (50)

1. Aniksztejn L, Bregestovski P, Ben-Ari Y (1991). Selective activation of quisqualate metabotropic receptor potentiates NMDA but not AMPA responses. Eur J Pharmacol 205:327-328.
2. Attucci S, Carla V, Mannaioni G, Moroni F (2001). Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges. Br J Pharmacol 132:799-806.
3. Awad H, Hubert GW, Smith Y, Levey AI, Conn PJ (2000). Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. J Neurosci 20:7871-7879.
4. Biala G, Kotlinska J (1999). Blockade of the acquisition of ethanol-induced conditioned place preference by N-methyl-D-aspartate receptor antagonists. Alcohol Alcoholism 34:175-182.
5. Bienkowski P, Koros E, Kostowski W, Danysz W (1999). Effects of N-methyl-D-aspartate receptor antagonists on reinforced and nonreinforced responding for ethanol in rats. Alcohol 18:131-137.
6. Blitzer RD, Gil O, Landau EM (1990). Long-term potentiation in rat hippocampus is inhibited by low concentrations of ethanol. Brain Res 537:203-208.
7. Broadbent J, Weitemier AZ (1999). Dizocilpine (MK-801) prevents the development of sensitization to ethanol in DBA/2J mice. Alcohol Alcohol 34:283-288.
8. Broadbent J, Kampmueller KM, Koonse SA (2003). Expression of behavioral sensitization to ethanol by DBA/2J mice: the role of NMDA and non-NMDA glutamate receptors. Psychopharmacology (Berl) 167:225-234.
9. Busse CS, Brodkin J, Tattersall D, Anderson JJ, Warren N, Tehrani L, et al. (2004). The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety. Neuropsychopharmacology 29:1971-1979.
10. Camarini R, Frussa-Filho R, Monteiro MG, Calil HM (2000). MK-801 blocks the development of behavioral sensitization to ethanol. Alcohol Clin Exp Res 24:285-290.
11. Danysz W, Dyr W, Jankowska E, Glazewski S, Kostowski W (1992). The involvement of NMDA receptors in acute and chronic effects of ethanol. Alcohol Clin Exp Res 16:499-504.
12. De Vries TJ, Schoffelmeer AN, Binnekade R, Mulder AH, Vanderschuren LJ (1998). Drug-induced reinstatemant of heroin- and cocain-seeking behavior following long-term extinction is associated with expression of behavioral sensitization. Eur J Neurosci 10:3565-3571.
13. Doherty AJ, Palmer MJ, Bortolotto ZA, Hargreaves A, Kingston AE, Ornstein PL, et al. (2000). A novel, competitive mGlu(5) receptor antagonist (LY344545) blocks DHPG-induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices. Br J Pharmacol 131:239-244.
14. Fish EW, DeBold JF, Miczek KA (2002). Repeated alcohol: behavioral sensitization and alcohol-heightened aggression in mice. Psychopharmacology 160:39-48.
15. Fitzjohn SM, Irving AJ, Palmer MJ, Harvey J, Lodge D, Collingridge GL (1996). Activation of group I mGluRs potentiates NMDA responses in rat hippocampal slices. Neurosci Lett 203:211-213.
16. Gonzales RA, Job MO, Doyon WM (2004). The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacol Ther 103:121-146.
17. Harris BR, Prendergast MA, Gibson DA, Rogers DT, Blanchard JA, Holley RC, et al. (2002). Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors. Alcohol Clin Exp Res 26:1779-1793.
18. Harvey J, Collingridge GL (1993). Signal transduction pathways involved in the acute potentiation of NMDA responses by 1S,3R-ACPD in rat hippocampal slices. Br J Pharmacol 109:1085-1090.
19. Heidbreder CA, Hagan JJ (2005). Novel pharmacotherapeutic approaches for the treatment of drug addiction and craving. Curr Opin Pharmacol 5:107-118.
20. Hodge CW, Cox AA (1998). The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions. Psychopharmacology (Berlin) 139:95-107.
21. Hunt WA, Lands WEM (1992). A role for behavioral sensitization in uncontrolled ethanol intake. Alcohol 9:327-328.
22. Kalivas PW (1995). Interactions between dopamine and excitatory amino acids in behavioral sensitization to psychostimulants. Drug Alcohol Depend 37:95-100.
23. Kalivas PW, Stewart J (1991). Dopamine transmission in the initiation and expression of drugs and stress induced sensitization. Brain Res Rev 16:223-224.
24. Kenny PJ, Markou A (2004). The ups and downs of addiction: role of metabotropic glutamate receptors. Trends Pharmacol Sci 25:265-272.
25. Koob GF, Roberts AJ, Schulteis G, Parsons LH, Heyser CJ, Hyytia P, et al. (1998). Neurocircuitry targets in ethanol reward and dependence. Alcohol Clin Exp Res 22:3-9.
26. Kotlinska J, Biala G, Rafalski P, Bochenski M, Danysz W (2004) Effect of neramexane on ethanol dependence and reinforcement. Eur J Pharmacol 503:95-98.
27. Krystal JH, Tabakoff B (2002). Ethanol abuse, dependence, and withdrawal: neurobiology and clinical implications. In: Davis KL, Charney DS, Coyle JT, Nemeroff C, editors. Psychopharmacology: a fifth generation of progress. Philadelphia: Lippincott Williams & Wilkins. pp. 1425-1443.
28. Krystal JH, Petrakis IL, Mason G, Trevisan L, D'Sousa DC (2003). N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability. Pharmacol Ther 99:79-94.
29. Lesage ASJ, Bischoff F, Van Beijsterveldt L, Meert T, Steckler T, Ashton D (2002). Novel, centrally active mGluR1 antagonists: in vitro and in vivo pharmacology. Neuropharmacology 43:295.
30. Lessov CN, Phillips TJ (1998). Duration of sensitization to the locomotor stimulant effects of ethanol in mice. Psychopharmacology (Berlin) 135:374-382.
31. Lhuintre JP, Daoust M, Moore ND, Chretien P, Saligaut C, Tran G, et al. (1985). Ability of calcium bis acetyl homotaurine, a GABA agonist, to prevent relapse in weaned alcoholics. Lancet 4:1014-1016.
32. Lhuintre JP, Moore N, Tran G, Steru L, Langrenon S, Daoust M, et al. (1990). Acamprosate appears to decrease alcohol intake in weaned alcoholics. Alcohol Alcohol 25:613-622.
33. Littleton J (1995). Acamprosate in alcohol dependence: how does it work? Addiction 90:1179-1188.
34. Newlin DB, Thomson JB (1991). Chronic tolerance and sensitization to alcohol in sons of alcoholics. Alcohol Clin Exp Res 15:399-405.
35. Ninan I, Kulkarni SK (1998). 5-HT2A receptor antagonists block MK-801-induced stereotypy and hyperlocomotion. Eur J Pharmacol 358:111-116.
36. Olive MF, Nannini MA, Ou CJ, Koenig HN, Hodge CW (2002). Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. Eur J Pharmacol 437:55-61.
37. Parsons CG, Danysz W, Quack G (1998). Glutamate in CNS disorders as a target for drug development: an update. Drug News Perspect 11:523-579.
38. Parsons CG, Danysz W, Bartmann A, Spielmanns P, Frankiewicz T, Hesselink M, et al. (1999). Amino-alkyl-cyclohexanes are novel uncompetitive NMDA receptor antagonists with strong voltage-dependency and fast blocking kinetics: in vitro and in vivo characterization. Neuropharmacology 38:85-108.
39. Phillips TJ, Dickinson S, Burkhart-Kasch S (1994). Behavioral sensitization to drug stimulant effects in C57BL/6J and DBA/2J inbred mice. Behav Neurosci 108:789-809.
40. Rammes G, Mahal B, Putzke J, Parsons C, Spielmanns P, Pestel E, et al. (2001). The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801. Neuropharmacology 40:749-760.
41. Rassnick S, Pulvirenti L, Koob GF (1992). Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens. Psychopharmacology (Berlin) 109:92-98.
42. Robinson TE, Berridge KC (1993). The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Rev 18:247-291.
43. Robinson TE, Berridge KC (2000). The psychology and neurobiology of addiction: an incentive-sensitization view. Addiction 95 (Suppl 2):91-117.
44. Sass H, Soyka M, Mann K, Zieglgansberger W (1996). Relapse prevention by acamprosate. Results from a placebo-controlled study on alcohol dependence. Arch Gen Psychiatry 53:673-680.
45. Schroeder JP, Overstreet DH, Hodge CW (2005). The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats. Psychopharmacology (Berlin) 179:262-270.
46. Shelton KL, Balster RL (1997). Effects of gamma-aminobutyric acid agonists and N-methyl-D-aspartate antagonists on a multiple schedule of ethanol and saccharin self-administration in rats. J Pharmacol Exp Ther 280:1250-1260.
47. Thomas LS, Jane DE, Gasparini F, Croucher MJ (2001). Glutamate release inhibiting properties of the novel mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP): complementary in vitro and in vivo evidence. Neuropharmacology 41:523-527.
48. Vanderschuren LJ, Kalivas PW (2000). Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacology 151:99-120.
49. Wang JQ, McGinty JF (1996). Intrastriatal injection of the metabotropic glutamate receptor antagonist MCPG attenuates acute amphetamine-stimulated neuropeptide mRNA expression in rat striatum. Neurosci Lett 218:13-16.
50. Wolf ME (1998). The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants. Prog Neurobiol 54:679-720.