Amphetamine increases phosphorylation of extracellular signal-regulated kinase and transcription factors in the rat striatum via group I metabotropic glutamate receptors

Neuropsychopharmacology

Volumn 27, Issue 4, 2002, Pages 565-575

  Choe, Eun Sang ^a   Chung, Kyung Tae ^b   Mao, Limin ^a   Wang, John Q ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Calcium; CREB; Dopamine; Drugs of abuse; Elk 1; ERK; Fos

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; ALPHA METHYLSERINE O PHOSPHATE; AMIDE; AMPHETAMINE; CALCIUM ION; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DANTROLENE; ESTER; GLUTAMATE RECEPTOR ANTAGONIST; METABOTROPIC RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; N PHENYL 7 (HYDROXYIMINO)CYCLOPROPA[B]CHROMEN 1A CARBOXAMIDE; PROTEIN FOS; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME PHOSPHORYLATION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INDUCTION; RAT; RECEPTOR BLOCKING; WESTERN BLOTTING;

AMPHETAMINE; AMPHETAMINE-RELATED DISORDERS; ANIMALS; BENZOPYRANS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DANTROLENE; DNA-BINDING PROTEINS; ETS-DOMAIN PROTEIN ELK-1; EXCITATORY AMINO ACID ANTAGONISTS; IMMUNOHISTOCHEMISTRY; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE RELAXANTS, CENTRAL; NEOSTRIATUM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PHOSPHOSERINE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FOS; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 0036789802     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(02)00341-X     Document Type: Article

References (40)

1. Adams DH, Hanson GR, Keefe KA (2001): Psychostimulants activate p42/44 MAPK in dorsal and ventral striatum. Soc Neurosci Abstr 27:445.2
2. Ahn Y.M., Oh S.W., Kang U.G., Park J., Kim Y.S. An N-methyl-D-aspartate antagonist, MK-801, preferentially reduces electroconvulsive shock-induced phosphorylation of p38 mitogen-activated protein kinase in the rat hippocampus. Neurosci Lett. 296:2000;101-104.
3. Alagarsamy S., Marino M.J., Rouse S.T., Gereau R.W., Heinemann S.F., Conn P.J. Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems. Nat Neurosci. 2:1999;234-240.
4. Cartmell J., Monn J.A., Schoepp D.D. The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats. J Pharmacol Exp Ther. 291:1999;161-170.
5. Cartmell J., Monn J.A., Schoepp D.D. The mGlu(2/3) receptor agonist LY379268 selectively blocks amphetamine ambulations and rearing. Eur J Pharmacol. 400:2000;221-224.
6. Choe E.S., McGinty J.F. N-Methyl-D-aspartate receptors and p38 mitogen-activated protein kinase are required for cAMP-dependent cyclase response element binding protein and Elk-1 phosphorylation in the striatum. Neuroscience. 101:2000;607-617.
7. Choe E.S., McGinty J.F. Cyclic AMP and mitogen-activated protein kinases are required for glutamate-dependent cyclic AMP response element binding protein and Elk-1 phosphorylation in the dorsal striatum in vivo. J Neurochem. 76:2001;401-412.
8. Choe E.S., Wang J.Q. Group I metabotropic glutamate receptor activation increases phosphorylation of cAMP response element-binding protein, extracellular signal-regulated kinases, and Elk-1 in rat dorsal striatum. Mol Brain Res. 94:2001;75-84.
9. Choe E.S., Wang J.Q. Regulation of transcription factor phosphorylation by metabotropic glutamate receptor-associated signaling pathways in rat striatal neurons. Neuroscience. in press:2002.
10. Dale L.B., Babwah A.V., Bhattacharya M., Kelvin D.J., Ferguson S.S. Spatial-temporal patterning of metabotropic glutamate receptor-mediated Inositol 1,4,5-triphosphate, calcium, and protein kinase C oscillations. Protein kinase C-dependent receptor phosphorylation is not required J Biol Chem. 276:2001;35900-35908.
11. Das S., Grunert M., Williams L., Vincent S.R. NMDA and D1 receptors regulate the phosphorylation of CREB and the induction of c-fos in striatal neurons in primary culture. Synapse. 25:1997;227-233.
12. Davis S., Vanhoutte P., Pages C., Caboche J., Laroche S. The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo. J Neurosci. 20:2000;4563-4572.
13. de Rooij J., Zwartkruis F.J., Verheijen M.H., Cool R.H., Nijman S.M., Wittinghofer A., Bos J.L. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature. 396:1998;474-477.
14. Del Arco A., Gonzalez-Mora J.L., Armas V.R., Mora F. Amphetamine increases the extracellular concentration of glutamate in striatum of the awake rat. involvement of high affinity transporter mechanisms Neuropharmacology. 38:1999;943-954.
15. Ferraguti F., Baldani-Guerra B., Corsi M., Nakanishi S., Corti C. Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors. Eur J Neurosci. 11:1999;2073-2082.
16. Fiore R.S., Murphy T.H., Sanghera J.S., Pelech S.L., Baraban J.M. Activation of p42 mitogen-activated protein kinase by glutamate receptor stimulation in rat primary cortical cultures. J Neurochem. 61:1993;1626-1633.
17. Hisatsune C., Umemori H., Inoue T., Michikawa T., Kohda K., Mikoshiba K., Yamamoto T. Phosphorylation-dependent regulation of N-methyl-D-aspartate receptors by calmodulin. J Biol Chem. 272:1997;20805-20810.
18. 2+ stimulation of CREB-dependent transcription and ERK nuclear translocation. Neuron. 21:1998;869-883.
19. Jiang Q., Gu Z., Zhang G., Jing G. N-methyl-D-aspartate receptor activation results in regulation of extracellular signal-regulated kinases by protein kinases and phosphatases in glutamate-induced neuronal apototic-like death. Brain Res. 887:2000;285-292.
20. Karim F., Wang C.C., Gereau R.W. Metabotropic glutamate receptor subtypes 1 and 5 are activators of extracellular signal-regulated kinase signaling required for inflammatory pain in mice. J Neurosci. 21:2001;3771-3779.
21. Kawabata S., Kohara A., Tsutsumi R., Itahana H., Hayashibe S., Yamaguchi T., Okada M. Diversity of calcium signaling by metabotropic glutamate receptors. J Biol Chem. 273:1998;17381-17385.
22. Kawasaki H., Springett G.M., Mochizuki N., Toki S., Nakaya M., Matsuda M., Housman D.E., Graybiel A.M. A family of cAMP-binding proteins that directly activate Rap1. Science. 282:1998;2275-2279.
23. Konradi C., Cole R.L., Heckers S., Hyman S.E. Amphetamine regulates gene expression in rat striatum via transcription factor CREB. J Neurosci. 14:1994;5623-5634.
24. Mao L., Wang J.Q. Protection against acute amphetamine-induced behavior by microinjection of a group II metabotropic glutamate receptor agonist into the dorsal striatum of rats. Neurosci Lett. 270:1999;103-106.
25. Mao L., Wang J.Q. Distinct inhibition of acute cocaine-stimulated motor activity following microinjection of a group III metabotropic glutamate receptor agonist into the dorsal striatum of rats. Pharmacol Biochem Behav. 67:2000;93-101.
26. Mao L., Lau Y.S., Wang J.Q. Activation of group III metabotropic glutamate receptors inhibits basal and amphetamine-stimulated dopamine release in rat dorsal striatum. an in vivo microdialysis study Eur J Pharmacol. 404:2000;289-297.
27. Nash J.F., Yamamoto B.K. Effect of D-amphetamine on the extracellular concentrations of glutamate and dopamine in iprindole-treated rats. Brain Res. 627:1993;1-8.
28. Peavy R.D., Conn P.J. Phosphorylation of mitogen-activated protein kinase in cultured rat cortical glia by stimulation of metabotropic glutamate receptors. J Neurochem. 71:1998;603-612.
29. Rawls S.M., McGinty J.F. Delta opioid receptors regulate calcium-dependent, amphetamine-evoked glutamate levels in the rat striatum. an in vivo microdialysis study Brain Res. 861:2000;296-304.
30. Roberson E.D., English J.D., Adams J.P., Selcher J.C., Kondratick C., Sweatt J.D. The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus. J Neurosci. 19:1999;4337-4348.
31. Schinkmann K.A., Kim T.A., Avraham S. Glutamate-stimulated activation of DNA synthesis via mitogen-activated protein kinase in primary astrocytes. involvement of protein kinase C and related adhesion focal tyrosine kinase J Neurochem. 74:2000;1931-1940.
32. Schnabel R., Kilpatrick I.C., Collingridge G.L. An investigation into signal transduction mechanisms involved in DHPG-induced LTD in the CA1 region of the hippocampus. Neuropharmacology. 38:1999;1585-1596.
33. Sgambato V., Pages C., Rogard M., Besson M.J., Caboche J. Extracellular signal-regulated kinase (ERK) controls immediate early gene induction on corticostriatal stimulation. J Neurosci. 18:1998;8814-8825.
34. Simpson J.N., Wang J.Q., McGinty J.F. Repeated amphetamine administration induces a prolonged augmentation of phosphorylated cyclase response element-binding protein and Fos-related antigen immunoreactivity in rat striatum. Neuroscience. 69:1995;441-457.
35. Spooren W.P., Gasparini F., Bergmann R., Kuhn R. Effects of the prototypical mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine on rotarod, locomotor activity and rotational responses in unilateral 6-OHDA-lesioned rats. Eur J Pharmacol. 406:2000;403-410.
36. Testa C.M., Standaert D.G., Young A.B., Penney J.B. Jr. Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat. J Neurosci. 14:1994;3005-3018.
37. Wang J.Q., Mao L. Sustained behavioral stimulation following selective activation of group I metabotropic glutamate receptors in rat striatum. Pharmacol Biochem Behav. 65:2000;439-447.
38. Vanhoutte P., Barnier J.V., Guibert B., Pages C., Besson M.J., Hipskind R.A., Caboche J. Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices. Mol Cell Biol. 19:1999;136-146.
39. Vincent S.R., Sebben M., Dumuis A., Bockaert J. Neurotransmitter regulation of MAP kinase signaling in striatal neurons in primary culture. Synapse. 29:1998;29-36.
40. Vossler M.R., Yao H., York R.D., Pan M.G., Rim C.S., Stork P.J. cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell. 89:1997;73-82.