Cocaine self-administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortex

Synapse

Volumn 39, Issue 3, 2001, Pages 257-266

  Robinson, Terry E ^a,c   Gorny, Grazyna ^b   Mitton, Elizabeth ^a   Kolb, Bryan ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF LETHBRIDGE   (Canada)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Golgi; Neuronal morphology; Plasticity; Prefrontal cortex; Sensitization

Indexed keywords

COCAINE;

ADDICTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DECISION MAKING; DENDRITE; DENDRITIC SPINE; DRUG SELF ADMINISTRATION; GOLGI STAIN; MALE; NEOCORTEX; NERVE; NEUROPATHOLOGY; NONHUMAN; NUCLEUS ACCUMBENS; PARIETAL LOBE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

ANIMALS; COCAINE; DENDRITES; DOPAMINE UPTAKE INHIBITORS; MALE; NEOCORTEX; NUCLEUS ACCUMBENS; OCCIPITAL LOBE; PARIETAL LOBE; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0035283646     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2396(20010301)39:3<257::AID-SYN1007>3.0.CO;2-1     Document Type: Article

References (82)

1. Long-term potentiation and spatial training are both associated with the generation of new excitatory synapses
2. Striatal acetylcholine release correlates with behavioral sensitization in rats withdrawn from chronic amphetamine
3. Event-related potential evidence for frontal cortex effects of chronic cocaine dependence
4. The neuropsychiatry of chronic cocaine abuse
5. The influence of environment on the induction of sensitization to the psychomotor activating effects of intravenous cocaine in rats is dose-dependent
6. Intravenous drug self-administration techniques in animals
7. Time-dependent effects of repeated amphetamine treatment on norepinephrine in the hypothalamus and hippocampus assessed with in vivo microdialysis
8. Rewarding actions of phencyclidine and related drugs in nucleus accumbens shell and frontal cortex
9. Lateralized effects of monocular training on dendritic branching in adult split-brain rats
10. Alterations in excitatory amino acid-mediated regulation of midbrain dopaminergic neurones induced by chronic psychostimulant administration and stress: Relevance to behavioral sensitization and drug addiction
11. Environmental effects on cortical dendritic fields. I. Rearing in the dark
12. Differential rearing alters spine density on medium-sized spiny neurons in the rat corpus striatum: Evidence for association of morphological plasticity with early response gene expression
13. Increased density of multiple-head dendritic spines on medium-sized spiny neurons of the striatum in rats reared in a complex environment
14. Signalled versus unsignalled intravenous amphetamine: Large differences in the acute psychomotor response and sensitization
15. Reinstatement of drug-seeking behavior following long-term extinction of cocaine and heroin self-administration: Possible role of behavioral sensitization
16. Drug-induced reinstatement of heroin- and cocaine-seeking behaviour following long-term extinction is associated with expression of behavioural sensitization
17. Dopaminergic mechanisms mediating the incentive to seek cocaine and heroin following long-term withdrawal of IV drug selfadministration
18. Cocaine self-administration increases the incentive motivational properties of the drug in rats
19. Rat brain neurotransmitter turnover rates altered during withdrawal from chronic cocaine administration
20. Response-dependent versus response-independent presentation of cocaine: Differences in the lethal effects of the drug
21. Nomenclature and classification of drug- and alcohol-related problems: A WHO memorandum
22. Perforated synapses on double-headed dendritic spines: A possible structural substrate of synaptic plasticity
23. A method for vibratome sectioning of Golgi-Cox stained whole rat brain
24. Dopamine synaptic complex with pyramidal neurons in primate cerebral cortex
25. The anatomy of dopamine in monkey and human prefrontal cortex
26. Morphological changes in the nervous system arising from behavioral experience: What is the evidence that they are involved in learning and memory?
27. Functional anatomy of the ventral, limbic system-innervated striatum
28. Dendritic spines: Cellular specializations imparting both stability and flexibility to synaptic function
29. Preexposure sensitizes rats to the rewarding effects of cocaine
30. Plasticity of the dendritic spine
31. Current concepts of addiction
32. Impulsivity resulting from frontostriatal dysfunction in drug abuse: Implications for the control of behavior by reward-related stimuli
33. Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity
34. Blockade of "reverse tolerance" to cocaine and amphetamine by MK-801
35. Models of relative reinforcing efficacy of drugs and their predictive utility
36. The function of dendritic spines: Devices subserving biochemical rather than electrical compartmentalization
37. Age, experience and the changing brain
38. Cellular and molecular mechanisms of drug dependence
39. Repeated exposures intensify rather than diminish the rewarding effects of amphetamine, morphine, and cocaine
40. Self-administration of cocaine increases the release of acetylcholine to a greater extent than response-independent cocaine in the nucleus accumbens of rats
41. Animal models of drug craving
42. Pre-exposure of rats to amphetamine sensitizes self-administration of this drug under a progressive ratio schedule
43. Microcircuits in the nucleus accumbens' shell and core involved in cognition and reward
44. An increase in dendritic spine density on hippocampal CA1 pyramidal cells following spatial learning in adult rats suggests the formation of new synapses
45. Spatial training in a complex environment and isolation alter the spine distribution differently in rat CA1 pyramidal cells
46. Drug addiction: A model for the molecular basis of neural plasticity
47. Serotonin and dopamine sensitization in the nucleus accumbens, ventral tegmental area, and dorsal raphe nucleus following repeated cocaine administration
48. Factors that predict individual vulnerability to amphetamine self- administration
49. A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants
50. Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis
51. The neural basis of drug craving: An incentive-sensitization theory of addiction
52. Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by previous experience with amphetamine
53. Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine
54. Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats
55. Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: Evidence for monoaminergic mechanisms
56. Branching of active dendritic spines as a mechanism for controlling synaptic efficacy
57. Sensitization and tolerance in psycho-stimulant self-administration
58. Stimulant-induced psychosis: An evaluation of animal models
59. In the rat medial nucleus accumbens, hippocampal and catecholaminergic terminals converge on spiny neurons and are in apposition to each other
60. Chronic (-)deprenyl administration alters dendritic morphology of layer III pyramidal neurons in the prefrontal cortex of adult Bonnett monkeys
61. The dendritic spine: A multifunctional integrative unit
62. Sensitization to the conditioned rewarding effects of cocaine: Pharmacological and temporal characteristics
63. The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurons
64. Behavioral contingencies determine changes in drug-induced transmitter turnover
65. Double bouquet cells
66. Critical assessment of the involvement of perforations, spinules, and spine branching in hippocampal synapse formation
67. Morphological changes associated with stages of memory formation in the chick following passive avoidance training
68. Convergence of hippocampal and dopaminergic input onto identified neurons in the nucleus accumbens of the rat
69. Dendritic spine changes in rat dentate granule cells associated with long-term potentiation
70. Long-term potentiation is associated with new excitatory spine synapses on rat dentate granule cells
71. Cytoskeletal dynamics in dendritic spines: Direct modulation by glutamate receptors?
72. Dopaminergic mechanisms mediating the long-term expression of locomotor sensitization following pre-exposure to morphine or amphetamine
73. Changes in brain glucose metabolism in cocaine dependence and withdrawal
74. Long-term frontal brain metabolic changes in cocaine abusers
75. Long-term intravenous infusions
76. Neuroadaptations involved in amphetamine and cocaine addiction
77. Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine
78. The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants