Involvement of spinal metabotropic glutamate receptor 5 in the development of tolerance to morphine-induced antinociception

Journal of Neurochemistry

Volumn 94, Issue 5, 2005, Pages 1297-1305

  Narita, Minoru ^a   Suzuki, Masami ^a   Narita, Michiko ^a   Niikura, Keiichi ^a   Nakamura, Atsushi ^a   Miyatake, Mayumi ^a   Aoki, Takeshi ^a   Yajima, Yoshinori ^a   Suzuki, Tsutomu ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Antinociception; Metabotropic glutamate receptor 5; Morphine; Spinal cord; Synaptic plasticity; Tolerance

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 3,5 DIHYDROPHENYLGLYCINE; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR ANTAGONIST; MORPHINE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; ASTROCYTE; BINDING ASSAY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG REEXPOSURE; DRUG SELECTIVITY; DRUG TOLERANCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; LONG TERM EXPOSURE; MALE; MOUSE; NERVE CELL CULTURE; NERVE CELL EXCITABILITY; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RECEPTOR DENSITY; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL; SYNAPTIC TRANSMISSION; TISSUE DISTRIBUTION;

ANALGESICS, OPIOID; ANIMALS; CALCIUM; COCULTURE TECHNIQUES; DRUG TOLERANCE; EXCITATORY AMINO ACID ANTAGONISTS; INTRACELLULAR MEMBRANES; MALE; METHOXYHYDROXYPHENYLGLYCOL; MICE; MICE, INBRED ICR; MORPHINE; NEUROGLIA; NEURONS; NOCICEPTORS; OSMOLAR CONCENTRATION; PYRIDINES; RECEPTORS, METABOTROPIC GLUTAMATE; SPINAL CORD;

EID: 24144487021     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03296.x     Document Type: Article

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