Effects of mGlu1 and mGlu5 metabotropic glutamate antagonists to reverse morphine tolerance in mice

European Journal of Pharmacology

Volumn 492, Issue 2-3, 2004, Pages 137-142

  Smith, Forrest L ^a   Smith, Paul A ^a   Dewey, William L ^a   Javed, Ruby R ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

(Mouse); Analgesia; Metabotrobic glutamate receptors; Opioid tolerance; Phosphatidylinositol cascade

Indexed keywords

1 AMINO 1,5 INDANDICARBOXYLIC ACID; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 7 (HYDROXYIMINO)CYCLOPROPA[B]CHROMEN 1A CARBOXYLATE ETHYL ESTER; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; MORPHINE SULFATE; UNCLASSIFIED DRUG; 1-AMINOINDAN-1,5-DICARBOXYLIC ACID; 6 METHYL 2 (PHENYLETHYNYL)PYRIDINE; 6-METHYL-2-(PHENYLETHYNYL)PYRIDINE; INDAN DERIVATIVE; METABOTROPIC GLUTAMATE RECEPTOR TYPE 1; MORPHINE; NARCOTIC ANALGESIC AGENT; PYRIDINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; LATENT PERIOD; MALE; MORPHINE TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR SENSITIVITY; WITHDRAWAL REFLEX; ANIMAL; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG TOLERANCE; PAIN ASSESSMENT; TAIL;

ANALGESICS, OPIOID; ANIMALS; DRUG TOLERANCE; INDANS; MALE; MICE; MORPHINE; PAIN MEASUREMENT; PYRIDINES; RECEPTORS, METABOTROPIC GLUTAMATE; TAIL;

EID: 2642520288     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.03.055     Document Type: Article

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