Calpains as a target for therapy of neurodegenerative diseases: Putative role of lithium

Current Drug Metabolism

Volumn 10, Issue 5, 2009, Pages 433-447

  Camins, Antoni ^a   Crespo Biel, Natalia ^a   Junyent, Félix ^a   Verdaguer, Ester ^a   Canudas, Anna M ^a   Pallàs, Mercè ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Apoptosis; Calcium homeostasis; Calpain; Cell cycle control; Cytoskeleton; DNA damage; Kinases; Lithium; Neurodegeneration; Neurodegenerative diseases; Signal transduction; Tau kinases

Indexed keywords

ALPHA SYNUCLEIN; AMPA RECEPTOR; APOPTOSIS INDUCING FACTOR; BETA CATENIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCINEURIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALPAIN; CALPAIN 1; CALPAIN 2; CASPASE; CATHEPSIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN DEPENDENT KINASE 5; GLYCOGEN SYNTHASE KINASE 3; HUNTINGTIN; INOSITOL TRISPHOSPHATE; LITHIUM; METABOTROPIC RECEPTOR 1; MICROTUBULE ASSOCIATED PROTEIN 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN BCL 2; RYANODINE RECEPTOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SPECTRIN; TAU PROTEIN; TRANSCRIPTION FACTOR; LITHIUM DERIVATIVE; TRANQUILIZER;

APOPTOSIS; AUTOPHAGY; CALCIUM HOMEOSTASIS; CELL CYCLE REGULATION; CELL DEATH; CELL SURVIVAL; CONFORMATIONAL TRANSITION; DEGENERATIVE DISEASE; DRUG TARGETING; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; HUMAN; MODULATION; MOOD DISORDER; MUSCLE FIBER MEMBRANE; NEUROPROTECTION; NONHUMAN; PROTEIN CLEAVAGE; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; CLINICAL TRIAL; DRUG DELIVERY SYSTEM; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY;

ANIMALS; ANTIMANIC AGENTS; APOPTOSIS; CALPAIN; CLINICAL TRIALS AS TOPIC; DRUG DELIVERY SYSTEMS; HUMANS; LITHIUM COMPOUNDS; NEURODEGENERATIVE DISEASES; NEURONS;

EID: 70350752515     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920009788898028     Document Type: Review

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