Crystal structure of calpain reveals the structural basis for Ca2+-dependent protease activity and a novel mode of enzyme activation

EMBO Journal

Volumn 18, Issue 24, 1999, Pages 6880-6889

  Hosfield, Christopher M ^a   Elce, John S ^a   Davies, Peter L ^a   Jia, Zongchao ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Calcium; Calpain; Cysteine proteases; Protease activation; Protease structure

Indexed keywords

CALCIUM ION; CALPAIN; PROTEINASE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; ENZYME SUBUNIT; PRIORITY JOURNAL; STEREOCHEMISTRY;

EID: 0033573028     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.24.6880     Document Type: Article

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