Activation of m-calpain (calpain II) by epidermal growth factor is limited by protein kinase A phosphorylation of m-calpain

Molecular and Cellular Biology

Volumn 22, Issue 8, 2002, Pages 2716-2727

  Shiraha, Hidenori ^a   Glading, Angela ^a   Chou, Jeffrey ^a   Jia, Zongchao ^a   Wells, Alan ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; ALPHA CHEMOKINE; CALPAIN; CALPAIN II; CHEMOKINE RECEPTOR CXCR3; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; EPIDERMAL GROWTH FACTOR; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; MONOKINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN SUBUNIT; SERINE; THROMBOCYTE FACTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MOTILITY; CONSENSUS SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST; GENETIC ENGINEERING; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY SEQUENCE; SECOND MESSENGER;

ANIMALS; CALPAIN; CELL LINE; CELL MOVEMENT; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; HUMANS; MICE; MODELS, MOLECULAR; MUTATION; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0036207773     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.8.2716-2727.2002     Document Type: Article

References (49)

1. 2+-dependent cysteine proteinase, calpains I and II are not phosphorylated in vivo
2. EGF-induced matrix contraction is modulated by calpain
3. Changes in intracellular calpastatin localization are mediated by reversible phosphorylation
4. Enhancement of wound healing by topical treatment with epidermal growth factor
5. Calpain: A protease in search of a function?
6. FAK, paxillin, and talin
7. Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis
8. Mitogenic signaling from the EGF receptor is attenuated by a phospholipase C-γ/protein kinase C feedback mechanism
9. Interferon-inducible T cell alpha chemoattractant (I-TAC): A novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3
10. Inhibition by cAMP of Ras-dependent activation of Raf
11. FAK) cleavage and regulation by calpain
12. 3 subunit
13. 2+ requirement, and heterodimer stability in m-calpain
14. Chemokines IL-8, GROα, MCP-1, IP-10, and Mig are sequentially and differentially expressed during phase-specific infiltration of leukocyte subsets in human wound healing
15. The role of cyclic nucleotides in the cell cycle
16. Effect of adenosine 3′-5′-cyclic monophosphate on cell proliferation
17. Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway
18. Membrane-proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling
19. The chemokine repertoire of human dermal microvascular endothelial cells and its regulation by inflammatory cytokines
20. William Montagna Lecture. Cyclic nucleotides and epidermal cell proliferation
21. 2+ mobilization patterns
22. 2+-dependent protease activity and a novel mode of enzyme activation
23. 2-like domain
24. Regulation of cell migration by the calcium-dependent protease calpain
25. 2+-activated neutral protease
26. Mutations in calpain 3 associated with limb girdle muscular dystrophy: Analysis by molecular modelling and by mutation in m-calpain
27. 2+/calmodulin-dependent protein kinase II
28. Calpains: Intact and active?
29. Proteolysis of tau by calpain
30. Degradation of microtubule-associated protein 2 and brain spectrin by calpain: A comparative study
31. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
32. Regulation of the phosphorylation of calpain II and its inhibitor
33. A comparison of the intracellular distribution of mu-calpain, m-calpain, and calpastatin in proliferating human A431 cells
34. Cell migration: A physically integrated molecular process
35. Phosphorylarion by cAMP-dependent protein kinase inhibits the degradation of tau by calpain
36. Biophysical integration of effects of epidermal growth factor and fibronectin on fibroblast migration
37. 2+/calmodulin dependent protein kinase II phosphorylation site in vascular calpain II
38. Cross-talk between two cysteine protease families: Activation of caspase-12 by calpain in apoptosis
39. Boosting epidermal growth factor receptor expression by gene gun transfection stimulates epidermal growth in vivo
40. Physical and biochemical regulation of integrin release during rear detachment of migrating cells
41. Calpain activity increases in hepatocytes following addition of ATP. Demonstration by a novel fluorescent approach
42. IP-10 inhibits epidermal growth factor-induced motility by decreasing epidermal growth factor receptor-mediated calpain activity
43. Proteases, proteolysis, and apoptosis
44. Structure and physiological function of calpains
45. The structure of calpain
46. The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium
47. Epidermal growth factor alters fibroblast migration speed and directional persistence reciprocally and in a matrix-dependent manner
48. Epidermal growth factor receptor-mediated motility in fibroblasts
49. EGF receptor regulation of cell motility: EGF induces disassembly of focal adhesions independently of the motility-associated PLCγ signaling pathway