Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2

Journal of Neuroscience

Volumn 25, Issue 19, 2005, Pages 4823-4834

  Tang, Xiaoli ^a   Wang, Xuemin ^a,d   Gong, Xiaoming ^a,e   Tong, Ming ^a   Park, David ^b   Xia, Zhengui ^c   Mao, Zixu ^a,d  

^a RHODE ISLAND HOSPITAL   (United States)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF WASHINGTON   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WOMEN AND INFANTS HOSPITAL   (United States)

Author keywords

Caspase; Cdk5; MEF2; Neuronal apoptosis; Neurotoxicity; Transcription factor

Indexed keywords

CASPASE 3; CYCLIN DEPENDENT KINASE 5; GLUTAMIC ACID; MYOCYTE ENHANCER FACTOR 2; ROSCOVITINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RAT; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CASPASES; CELL COUNT; CELL DEATH; CELLS, CULTURED; CEREBELLUM; CHROMATIN; CYCLIN-DEPENDENT KINASE 5; DRUG INTERACTIONS; GLUTAMIC ACID; GREEN FLUORESCENT PROTEINS; LUCIFERASES; MYOGENIC REGULATORY FACTORS; NEURONS; NEUROTOXINS; OLIGOPEPTIDES; PROTEIN KINASE INHIBITORS; PURINES; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBCELLULAR FRACTIONS; TIME FACTORS; TRANSFECTION;

EID: 18644380959     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1331-05.2005     Document Type: Article

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