Chronic lithium treatment antagonizes glutamate-induced decrease of phosphorylated CREB in neurons via reducing protein phosphatase 1 and increasing MEK activities

Neuroscience

Volumn 116, Issue 2, 2003, Pages 425-435

  Kopnisky, K L ^a   Chalecka Franaszek, E ^a   Gonzalez Zulueta, M ^b   Chuang, D M ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b AGY Therapeutics Inc   (United States)

Author keywords

Cerebellar granule cells; CREB; Glutamate; Lithium; NMDA; Protein phosphatase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUTAMIC ACID; LITHIUM; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHOPROTEIN PHOSPHATASE 1; SERINE;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL CULTURE; CEREBELLUM; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 0037474056     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00573-0     Document Type: Article

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