-
1
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
1. Sherrington R, Rogaev EI, Liang Y, et al. (1995) Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375: 754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
-
2
-
-
0029150716
-
A familial Alzheimer's disease locus on chromosome 1
-
2. Levy-Lehad E, Wijsman EM, Nemens E, et al. (1995) A familial Alzheimer's disease locus on chromosome 1. Science 269: 970-973.
-
(1995)
Science
, vol.269
, pp. 970-973
-
-
Levy-Lehad, E.1
Wijsman, E.M.2
Nemens, E.3
-
3
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
3. Levy-Lahad E, Wasco W, Poorkaj P, et al. (1995) Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269: 973-977.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
-
4
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
4. Rogaev EI, Sherrington R, Rogaeva EA, et al. (1995) Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376: 775-778.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
-
5
-
-
15844425969
-
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo
-
5. Thinakaran G, Borchelt DR, Lee MK, et al. (1996) Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron 17: 181-190.
-
(1996)
Neuron
, vol.17
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
-
6
-
-
16044365171
-
The E280a presenilin 1 alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology
-
6. Lemere CA, Lopera F, Kosik KS, et al. (1996) The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology. Nat. Med. 2: 1146-1150.
-
(1996)
Nat. Med.
, vol.2
, pp. 1146-1150
-
-
Lemere, C.A.1
Lopera, F.2
Kosik, K.S.3
-
7
-
-
12644290265
-
Evidence for phosphorylation and oligomeric assembly of presenilin 1
-
7. Seeger M, Nordstedt C, Petanceska S, et al. (1997) Evidence for phosphorylation and oligomeric assembly of presenilin 1. Proc. Natl. Acad. Sci. U.S.A. 94: 5090-5094.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 5090-5094
-
-
Seeger, M.1
Nordstedt, C.2
Petanceska, S.3
-
8
-
-
0031920383
-
Stable association of presenilin derivatives and absence of presenilin interactions with APP
-
S. Thinakaran G, Regard JB, Boulton CML, et al. (1995) Stable association of presenilin derivatives and absence of presenilin interactions with APP. Neurobiol. Dis. 4: 438-453.
-
(1995)
Neurobiol. Dis.
, vol.4
, pp. 438-453
-
-
Thinakaran, G.1
Regard, J.B.2
Boulton, C.M.L.3
-
9
-
-
0032568821
-
The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains β-catenin
-
9. Yu G, Chen F, Levesque G, et al. (1998) The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains β-catenin. J. Biol. Chem. 273: 16470-16475.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16470-16475
-
-
Yu, G.1
Chen, F.2
Levesque, G.3
-
10
-
-
0029982341
-
Widespread neuronal expression of the presenilin-1 early-onset Alzheimer's disease gene in the murine brain
-
10. Cribbs DH, Chen L-S, Bende SM, LaFerla FM. (1996) Widespread neuronal expression of the presenilin-1 early-onset Alzheimer's disease gene in the murine brain. Am. J. Pathol. 148: 1797-1806.
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 1797-1806
-
-
Cribbs, D.H.1
Chen, L.-S.2
Bende, S.M.3
LaFerla, F.M.4
-
11
-
-
10144234151
-
Identification and neuron specific expression of the S182/presenilin 1 protein in human and rodent brains
-
11. Elder GA, Tezapsidis N, Carter J, et al. (1996) Identification and neuron specific expression of the S182/presenilin 1 protein in human and rodent brains. J. Neurosci. Res. 45: 308-320.
-
(1996)
J. Neurosci. Res.
, vol.45
, pp. 308-320
-
-
Elder, G.A.1
Tezapsidis, N.2
Carter, J.3
-
12
-
-
10544229795
-
Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues
-
12. Lee MK, Slunt HH, Martin LJ, et al. (1996) Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues. J. Neurosci. 16: 7513-7525.
-
(1996)
J. Neurosci.
, vol.16
, pp. 7513-7525
-
-
Lee, M.K.1
Slunt, H.H.2
Martin, L.J.3
-
13
-
-
0029984314
-
Immunohistochemical analysis of presenilin-1 expression in the mouse brain
-
13. Moussaoui S, Czech C, Pradier L, et al. (1996) Immunohistochemical analysis of presenilin-1 expression in the mouse brain. FFBS Lett. 383: 219-222.
-
(1996)
FFBS Lett.
, vol.383
, pp. 219-222
-
-
Moussaoui, S.1
Czech, C.2
Pradier, L.3
-
14
-
-
0030459831
-
In situ hybridization analysis of presenilin-1 mRNA in Alzheimer disease and in lesioned rat brain
-
14. Page K, Hollister R, Tanzi RE, Hyman BT. (1996) In situ hybridization analysis of presenilin-1 mRNA in Alzheimer disease and in lesioned rat brain. Proc. Natl. Acad. Sci. U.S.A. 93: 14020-14024.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 14020-14024
-
-
Page, K.1
Hollister, R.2
Tanzi, R.E.3
Hyman, B.T.4
-
15
-
-
0031017795
-
Light and electron microscopic localization of presenilin-1 in primate brain
-
15. Lah JL, Heilman CJ, Nash NR, Rees HD, Yi H, Counts SE, Levey AI. (1997) Light and electron microscopic localization of presenilin-1 in primate brain. J. Neurosci. 17: 1971-1980.
-
(1997)
J. Neurosci.
, vol.17
, pp. 1971-1980
-
-
Lah, J.L.1
Heilman, C.J.2
Nash, N.R.3
Rees, H.D.4
Yi, H.5
Counts, S.E.6
Levey, A.I.7
-
16
-
-
10544239098
-
Antibodies to presenilin proteins detect neurofibrillary tangles in Alzheimer's disease
-
16. Murphy GM Jr, Forno LS, Ellis WG, et al. (1996) Antibodies to presenilin proteins detect neurofibrillary tangles in Alzheimer's disease. Am. J. Pathol. 149: 1839-1846.
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 1839-1846
-
-
Murphy G.M., Jr.1
Forno, L.S.2
Ellis, W.G.3
-
17
-
-
0029843172
-
Widespread immunoreactivity of presenilin in neurons of normal and Alzheimer's disease brains: Double-labelling immunohistochemical study
-
17. Uchihara T, El Hachimi HK, Duyckaerts C, et al. (1996) Widespread immunoreactivity of presenilin in neurons of normal and Alzheimer's disease brains: double-labelling immunohistochemical study. Acta Neuropathol. 92: 325-330.
-
(1996)
Acta Neuropathol.
, vol.92
, pp. 325-330
-
-
Uchihara, T.1
El Hachimi, H.K.2
Duyckaerts, C.3
-
18
-
-
0342601539
-
Immunoreactivity of presenilin-1 in human, rat and mouse brain
-
18. Kim KS, Wegiel J, Sapienza V, Chen J, Hong H, Wisniewski HM. (1997) Immunoreactivity of presenilin-1 in human, rat and mouse brain. Brain Res. 757: 159-163.
-
(1997)
Brain Res.
, vol.757
, pp. 159-163
-
-
Kim, K.S.1
Wegiel, J.2
Sapienza, V.3
Chen, J.4
Hong, H.5
Wisniewski, H.M.6
-
19
-
-
0030293854
-
Protein topology of presenilin 1
-
19. Doan A, Thinakaran G, Borchelt DR, et al. (1996) Protein topology of presenilin 1. Neuron 17: 1023-1030.
-
(1996)
Neuron
, vol.17
, pp. 1023-1030
-
-
Doan, A.1
Thinakaran, G.2
Borchelt, D.R.3
-
20
-
-
13344282063
-
Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells
-
20. Kovacs DM, Fausett HJ, Page KJ, et al. (1996) Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nat. Med. 2: 224-229.
-
(1996)
Nat. Med.
, vol.2
, pp. 224-229
-
-
Kovacs, D.M.1
Fausett, H.J.2
Page, K.J.3
-
21
-
-
15444341611
-
Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins
-
21. De Strooper B, Beullens M, Contreras B, et al. (1997) Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins. J. Biol. Chem. 272: 3590-3598.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3590-3598
-
-
De Strooper, B.1
Beullens, M.2
Contreras, B.3
-
22
-
-
0030574051
-
Quantification of presenilin-1 mRNA in Alzheimer's disease brains
-
22. Johnston JA, Froelich S, Lannfelt L, Cowburn RF. (1996) Quantification of presenilin-1 mRNA in Alzheimer's disease brains. FEBS Lett. 394: 279-284.
-
(1996)
FEBS Lett.
, vol.394
, pp. 279-284
-
-
Johnston, J.A.1
Froelich, S.2
Lannfelt, L.3
Cowburn, R.F.4
-
23
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Aβ1-42/1-40 ratio in vitro and in vivo
-
23. Borchelt DR, Thinakaran G, Eckman CB, et al. (1996) Familial Alzheimer's disease-linked presenilin 1 variants elevate Aβ1-42/1-40 ratio in vitro and in vivo. Neuron 17: 1005-1013.
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
-
24
-
-
16044366039
-
Increased amyloid β42(43) in brains of mice expressing mutant presenilin 1
-
24. Duff K, Eckman C, Zehr C, et al. (1996) Increased amyloid β42(43) in brains of mice expressing mutant presenilin 1. Nature 383: 710-713.
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
-
25
-
-
16044373524
-
Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
25. Scheuner D, Eckman C, Jensen M, et al. (1996) Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2: 864-870.
-
(1996)
Nat. Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
-
26
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfectcd cells and transgenic mice
-
26. Citron M, Westaway D, Xia W, et al. (1997) Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfectcd cells and transgenic mice. Nat. Med. 3: 67-72.
-
(1997)
Nat. Med.
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
-
27
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
27. Borchelt DR, Ratovitski T, van Lare J, et al. (1997) Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19: 939-945.
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
-
28
-
-
0031950118
-
Proteasome inhibitors prevent the degradation of familial Alzheimer's disease-linked presenilin 1 and potentiate A β 42 recovery from human cells
-
28. Marambaud P, Ancolio K, Lopez-Perez E, Checler F. (1998) Proteasome inhibitors prevent the degradation of familial Alzheimer's disease-linked presenilin 1 and potentiate A β 42 recovery from human cells. Mol. Med. 4: 147-157.
-
(1998)
Mol. Med.
, vol.4
, pp. 147-157
-
-
Marambaud, P.1
Ancolio, K.2
Lopez-Perez, E.3
Checler, F.4
-
29
-
-
0030832449
-
Different effects of Alzheimer-associated mutations of presenilin 1 on its processing
-
29. Murayama O, Honda T, Mercken M, et al. (1997) Different effects of Alzheimer-associated mutations of presenilin 1 on its processing. Neurosci. Lett. 229: 61-64.
-
(1997)
Neurosci. Lett.
, vol.229
, pp. 61-64
-
-
Murayama, O.1
Honda, T.2
Mercken, M.3
-
30
-
-
0032556859
-
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
-
30. De Strooper B, Saftig P, Craessaerts K, et al. (1998) Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature 391: 387-390.
-
(1998)
Nature
, vol.391
, pp. 387-390
-
-
De Strooper, B.1
Saftig, P.2
Craessaerts, K.3
-
31
-
-
0029899649
-
Alteration of acylphosphatase levels in familial Alzheimer's disease fibroblasis with presenilin gene mutations
-
31. Liguri G, Cecchi C, Latorraca S, Pieri A, Sorbi S, Degl'Innocenti D, Ramponi G. (1996) Alteration of acylphosphatase levels in familial Alzheimer's disease fibroblasis with presenilin gene mutations. Neurosci. Lett. 210: 153-156.
-
(1996)
Neurosci. Lett.
, vol.210
, pp. 153-156
-
-
Liguri, G.1
Cecchi, C.2
Latorraca, S.3
Pieri, A.4
Sorbi, S.5
Degl'Innocenti, D.6
Ramponi, G.7
-
32
-
-
0030891662
-
Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid β-peptide
-
32. Guo Q, Furukawa K, Sopher BL, et al. (1996) Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid β-peptide. Neuroreport 8: 379-383.
-
(1996)
Neuroreport
, vol.8
, pp. 379-383
-
-
Guo, Q.1
Furukawa, K.2
Sopher, B.L.3
-
33
-
-
17744401440
-
Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm
-
33. Wong PC, Zheng H, Chen H, et al. (1997) Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm. Nature 387: 288-292.
-
(1997)
Nature
, vol.387
, pp. 288-292
-
-
Wong, P.C.1
Zheng, H.2
Chen, H.3
-
34
-
-
0030963658
-
Nerve growth factor independent reduction in choline acetyltransferase activity in PC12 cells expressing mutant presenilin-1
-
34. Pederson WA, Guo Q, Hartman BK, Mattson MP. (1997) Nerve growth factor independent reduction in choline acetyltransferase activity in PC12 cells expressing mutant presenilin-1. J. Biol. Chem. 272: 22397-22400.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22397-22400
-
-
Pederson, W.A.1
Guo, Q.2
Hartman, B.K.3
Mattson, M.P.4
-
35
-
-
10544224542
-
Participation of presenilin 2 in apoptosis: Enhanced basal activity conferred by an Alzheimer mutation
-
35. Wolozin B, Iwasaki K, Vito P, et al. (1996) Participation of presenilin 2 in apoptosis: Enhanced basal activity conferred by an Alzheimer mutation. Science 274: 1710-1713.
-
(1996)
Science
, vol.274
, pp. 1710-1713
-
-
Wolozin, B.1
Iwasaki, K.2
Vito, P.3
-
36
-
-
0029116848
-
Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene
-
36. Levitan D, Greenwald I. (1995) Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 377: 351-354.
-
(1995)
Nature
, vol.377
, pp. 351-354
-
-
Levitan, D.1
Greenwald, I.2
-
37
-
-
0030671560
-
HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling
-
37. Li X, Greenwald I. (1997) HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling. Proc. Natl. Acad. Sci. U.S.A. 94: 12204-12209.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 12204-12209
-
-
Li, X.1
Greenwald, I.2
-
38
-
-
0029906585
-
Assessment of normal and mutant presenilin function in Caenorhabditis elegans
-
38. Levitan D, Doyle TG, Brousseau D, et al. (1996) Assessment of normal and mutant presenilin function in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 93: 14940-14944.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 14940-14944
-
-
Levitan, D.1
Doyle, T.G.2
Brousseau, D.3
-
39
-
-
0031108103
-
Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing
-
39. Baumeister R, Leimer U, Zweckbronner I, Jakubek C, Grünberg J, Haass C. (1997) Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing. Genes Function 1: 149-159.
-
(1997)
Genes Function
, vol.1
, pp. 149-159
-
-
Baumeister, R.1
Leimer, U.2
Zweckbronner, I.3
Jakubek, C.4
Grünberg, J.5
Haass, C.6
-
40
-
-
0033535504
-
A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
-
40. De Strooper B, Annaert W, Cupers P, et al. (1999) A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain. Nature 398: 518-522.
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
-
41
-
-
0033535508
-
Presenilin is required for activity and nuclear access of Notch in Drosophila
-
41. Struhl G, Greenwald I. (1999) Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature 398: 522-526.
-
(1999)
Nature
, vol.398
, pp. 522-526
-
-
Struhl, G.1
Greenwald, I.2
-
42
-
-
0033535555
-
Neurogenic phenotypes and altered Notch processing in Drosophila presenilin mutants
-
42. Ye Y, Lukinova N, Fortini ME. (1999) Neurogenic phenotypes and altered Notch processing in Drosophila presenilin mutants. Nature 398: 525-529.
-
(1999)
Nature
, vol.398
, pp. 525-529
-
-
Ye, Y.1
Lukinova, N.2
Fortini, M.E.3
-
43
-
-
0029966488
-
Molecular cloning and expression of the rat homologue of presenilin-1
-
43. Takahashi H, Murayama M, Takashima A, et al. (1996) Molecular cloning and expression of the rat homologue of presenilin-1. Neurosci. Lett. 206: 113-116.
-
(1996)
Neurosci. Lett.
, vol.206
, pp. 113-116
-
-
Takahashi, H.1
Murayama, M.2
Takashima, A.3
-
44
-
-
0030638153
-
Developmental regulation of presenilin mRNA expression parallels Notch expression
-
44. Berezovska O, Xia MQ, Page K, Wasco W, Tanzi RE, Hyman BT, (1997) Developmental regulation of presenilin mRNA expression parallels Notch expression. J. Neuropathol. Exp. Neurol. 56: 40-44.
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 40-44
-
-
Berezovska, O.1
Xia, M.Q.2
Page, K.3
Wasco, W.4
Tanzi, R.E.5
Hyman, B.T.6
-
45
-
-
0031004532
-
Developmental regulation of presenilin-1 processing in the brain suggests a role in neuronal differentiation
-
45. Hartmann H, Busciglio J, Baumann K-H, Staufenbiel M, Yankner BA. (1997) Developmental regulation of presenilin-1 processing in the brain suggests a role in neuronal differentiation. J. Biol. Chem. 272: 14505-14508.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14505-14508
-
-
Hartmann, H.1
Busciglio, J.2
Baumann, K.-H.3
Staufenbiel, M.4
Yankner, B.A.5
-
46
-
-
0030779784
-
Skeletal and CNS defects in presenilin-1-deficient mice
-
46. Shen J, Bronson RT, Chen DF, Xia W, Selkoe DJ, Tonegawa S. (1997) Skeletal and CNS defects in presenilin-1-deficient mice. Cell 89: 629-639.
-
(1997)
Cell
, vol.89
, pp. 629-639
-
-
Shen, J.1
Bronson, R.T.2
Chen, D.F.3
Xia, W.4
Selkoe, D.J.5
Tonegawa, S.6
-
47
-
-
0028989016
-
Notch 1 is required for the coordinate segmentation of somites
-
47. Conlon RA, Reaume AG, Rossant J. (1995) Notch 1 is required for the coordinate segmentation of somites. Development 121: 1533-1545.
-
(1995)
Development
, vol.121
, pp. 1533-1545
-
-
Conlon, R.A.1
Reaume, A.G.2
Rossant, J.3
-
48
-
-
0002329664
-
Rat hippocampal neurons in low density cultures
-
Banker G, Goslin K (eds). MIT Press, Cambridge
-
48. Goslin K, Banker GA. (1991) Rat hippocampal neurons in low density cultures. In: Banker G, Goslin K (eds). Culturing Nerve Cells. MIT Press, Cambridge, pp. 251-281.
-
(1991)
Culturing Nerve Cells
, pp. 251-281
-
-
Goslin, K.1
Banker, G.A.2
-
49
-
-
0030667426
-
Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors
-
49. Thinakaran G, Harris CL, Ratovitski T, et al. (1997) Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors. J. Biol. Chem. 272: 28415-28422.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28415-28422
-
-
Thinakaran, G.1
Harris, C.L.2
Ratovitski, T.3
-
50
-
-
0030854388
-
Endoproteolytic processing and stabilization of wild-type and mutant presenilin
-
50. Ratovitski T, Slunt HH, Thinakaran G, Price DL, Sisodia SS, Borchelt DR. (1997) Endoproteolytic processing and stabilization of wild-type and mutant presenilin. J. Biol. Chem. 272: 24536-24541.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24536-24541
-
-
Ratovitski, T.1
Slunt, H.H.2
Thinakaran, G.3
Price, D.L.4
Sisodia, S.S.5
Borchelt, D.R.6
-
51
-
-
0030657665
-
Cellular expression and proteolytic processing of presenilin proteins is developmentally regulated during neuronal differentiation
-
51. Capell A, Saffrich R, Olivo J-C, et al. (1997) Cellular expression and proteolytic processing of presenilin proteins is developmentally regulated during neuronal differentiation. J. Neurochem. 69: 2432-2440.
-
(1997)
J. Neurochem.
, vol.69
, pp. 2432-2440
-
-
Capell, A.1
Saffrich, R.2
Olivo, J.-C.3
-
52
-
-
0030889220
-
Presenilin proteins undergo heterogenous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue
-
52. Podlisny MB, Citron M, Amarante P, et al. (1997) Presenilin proteins undergo heterogenous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue. Neurobiol. Dis. 3: 325-337.
-
(1997)
Neurobiol. Dis.
, vol.3
, pp. 325-337
-
-
Podlisny, M.B.1
Citron, M.2
Amarante, P.3
-
53
-
-
0023905661
-
The establishment of polarity by hippocampal neurons in culture
-
53. Dotti CG, Sullivan CA, Banker GA. (1988) The establishment of polarity by hippocampal neurons in culture. J. Neurosci. 8: 1454-1468.
-
(1988)
J. Neurosci.
, vol.8
, pp. 1454-1468
-
-
Dotti, C.G.1
Sullivan, C.A.2
Banker, G.A.3
-
54
-
-
0028817907
-
The organization of the endoplasmic reticulum and the intermediate compartment in cultured rat hippocampal neurons
-
54. Krijnse-Locker J, Parton RG, Fuller SD, Griffiths G, Dotti CG. (1995) The organization of the endoplasmic reticulum and the intermediate compartment in cultured rat hippocampal neurons. Mol. Biol. Cell 6: 1315-1332.
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 1315-1332
-
-
Krijnse-Locker, J.1
Parton, R.G.2
Fuller, S.D.3
Griffiths, G.4
Dotti, C.G.5
-
57
-
-
0031968723
-
Presenilin 1 is acively degraded by the 26S proteasome
-
57. Fraser PE, Levesque G, Yu G, et al. (1998) Presenilin 1 is acively degraded by the 26S proteasome. Neurobiol. Aging 19: S19-S21.
-
(1998)
Neurobiol. Aging
, vol.19
-
-
Fraser, P.E.1
Levesque, G.2
Yu, G.3
-
58
-
-
8044231311
-
The Alzheimer's disease associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum
-
58. Walter J, Capell A, Grünberg J, et al. (1996) The Alzheimer's disease associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum. Mol. Med. 2: 673-691.
-
(1996)
Mol. Med.
, vol.2
, pp. 673-691
-
-
Walter, J.1
Capell, A.2
Grünberg, J.3
-
59
-
-
0029812077
-
Expression and analysis of presenilin 1 in a human neuronal system: Localization in cell bodies and dendrites
-
59. Cook DB, Sung JC, Golde TE, et al. (1996) Expression and analysis of presenilin 1 in a human neuronal system: Localization in cell bodies and dendrites. Proc. Natl Acad. Sci. U.S.A. 93: 9223-9228.
-
(1996)
Proc. Natl Acad. Sci. U.S.A.
, vol.93
, pp. 9223-9228
-
-
Cook, D.B.1
Sung, J.C.2
Golde, T.E.3
-
60
-
-
0030923412
-
Alzheimer's disease-associated presenilin 1 in neuronal cells: Evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment
-
60. Culvenor JG, Maher F, Evin G, et al. (1997) Alzheimer's disease-associated presenilin 1 in neuronal cells: Evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment. J. Neurosci. Res. 49: 719-731.
-
(1997)
J. Neurosci. Res.
, vol.49
, pp. 719-731
-
-
Culvenor, J.G.1
Maher, F.2
Evin, G.3
-
61
-
-
0030904751
-
Presenilin-1 interaction in the brain with a novel member of the armadillo family
-
61. Zhou J, Liyangage U, Medina M, et al. (1997) Presenilin-1 interaction in the brain with a novel member of the armadillo family. Neuroreport 8: 1489-1494.
-
(1997)
Neuroreport
, vol.8
, pp. 1489-1494
-
-
Zhou, J.1
Liyangage, U.2
Medina, M.3
-
62
-
-
0029807018
-
The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones
-
62. Uchida N, Honjo Y, Johnson KR, Wheelock MJ, Takeichi M. (1996) The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones. J. Cell Biol. 135: 767-779.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 767-779
-
-
Uchida, N.1
Honjo, Y.2
Johnson, K.R.3
Wheelock, M.J.4
Takeichi, M.5
-
63
-
-
0033026550
-
Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain
-
63. Beher D, Elle C, Underwood J, et al. (1999) Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain. J. Neurochem. 72: 1564-1573.
-
(1999)
J. Neurochem.
, vol.72
, pp. 1564-1573
-
-
Beher, D.1
Elle, C.2
Underwood, J.3
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