Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration

Brain Research

Volumn 797, Issue 2, 1998, Pages 267-277

  Pei, Jin Jing ^a   Grundke Iqbal, Inge ^b   Iqbal, Khalid ^b   Bogdanovic, Nenad ^a   Winblad, Bengt ^a   Cowburn, Richard F ^a  

^a Dept of Clin Neurosci and Fam M ^*  (Sweden)

^b NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Alzheimer's disease; Cdk5; GSK 3; Hyperphosphorylated tau; MAP kinase; Neurofibrillary tangles

Indexed keywords

CYCLIN DEPENDENT KINASE; MITOGEN ACTIVATED PROTEIN KINASE;

ALZHEIMER DISEASE; ARTICLE; CELLULAR DISTRIBUTION; CEREBELLUM CORTEX; DRUG ACCUMULATION; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; MEMBRANE STABILIZATION; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; TISSUE DISTRIBUTION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CEREBRAL CORTEX; CYCLIN-DEPENDENT KINASE 5; CYCLIN-DEPENDENT KINASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; HUMANS; MALE; MIDDLE AGED; NERVE DEGENERATION; NEUROFIBRILLARY TANGLES; NEURONS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; TAU PROTEINS; TEMPORAL LOBE;

EID: 0032578024     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00296-0     Document Type: Article

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