Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite

Journal of Neurochemistry

Volumn 82, Issue 1, 2002, Pages 181-191

  Zhang, Xiaopeng ^a   Chen, Jun ^a,b   Graham, Steven H ^a,b   Du, Lina ^a   Kochanek, Patrick M ^a   Draviam, Romesh ^a   Guo, Fengli ^a   Nathaniel, Paula D ^a   Szabó, Csaba ^c   Watkins, Simon C ^a   Clark, Robert S B ^a,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c INOTEK CORPORATION   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Apoptosis; Brain injury; Controlled cortical impact; DNA damage; Programmed cell death

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE; DNA FRAGMENT; PEROXYNITRITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; EUCHROMATIN; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; MITOCHONDRIAL RESPIRATION; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BLOTTING, WESTERN; BRAIN CHEMISTRY; BRAIN INJURIES; CELL NUCLEUS; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DNA FRAGMENTATION; FLAVOPROTEINS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MICROSCOPY, IMMUNOELECTRON; NEURONS; PEROXYNITROUS ACID; RATS; RATS, SPRAGUE-DAWLEY; SUBCELLULAR FRACTIONS;

ANIMALIA;

EID: 20244364788     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00975.x     Document Type: Article

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