Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions

Neurotoxicity Research

Volumn 10, Issue 1, 2006, Pages 43-56

  Obrenovich, Mark E ^a   Smith, Mark A ^a   Siedlak, Sandra L ^a   Chen, Shu G ^a   Torre, Jack C ^a   Perry, George ^a   Aliev, Gjumrakch ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer disease; G protein coupled receptor kinase 2; GRK2; Mitochondrial damage; Neurodegeneration; Oxidative stress; Vascular hypoperfusion

Indexed keywords

ADRBK1 PROTEIN, HUMAN; BETA ADRENERGIC RECEPTOR KINASE; BIOLOGICAL MARKER;

AGED; ALZHEIMER DISEASE; ANIMAL; ARTICLE; BRAIN; CASE CONTROL STUDY; CEREBRAL ARTERY DISEASE; COMPARATIVE STUDY; DISEASE MODEL; FEMALE; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOELECTRON MICROSCOPY; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; MITOCHONDRION; PATHOLOGY; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; BIOLOGICAL MARKERS; BRAIN; CASE-CONTROL STUDIES; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICROSCOPY, IMMUNOELECTRON; MIDDLE AGED; MITOCHONDRIA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33750617659     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03033333     Document Type: Article

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