메뉴 건너뛰기




Volumn 5, Issue 3-4, 2008, Pages 126-132

Pathophysiology of neuronal energy crisis in Alzheimer's disease

Author keywords

Aging; Alzheimer's disease; Brain hypoperfusion; Critically attained threshold of cerebral hypoperfusion; Neuroimaging; Neuronal energy metabolism; Vascular risk factors

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; PROTEIN; REACTIVE OXYGEN METABOLITE; TAU PROTEIN;

EID: 40449117446     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000113681     Document Type: Conference Paper
Times cited : (114)

References (39)
  • 1
    • 33748925547 scopus 로고    scopus 로고
    • Impact of heart disease and stroke on Alzheimer's disease
    • de la Torre JC: Impact of heart disease and stroke on Alzheimer's disease. Neurol Res 2006;28:577-679.
    • (2006) Neurol Res , vol.28 , pp. 577-679
    • de la Torre, J.C.1
  • 3
    • 0029022511 scopus 로고
    • Correlates between NMR spectroscopy, diffusion weighted imaging and CA1 morphometry following chronic brain ischemia
    • de la Torre JC, Fortin T, Saunders J: Correlates between NMR spectroscopy, diffusion weighted imaging and CA1 morphometry following chronic brain ischemia. J Neurosci Res 1995;41:238-245.
    • (1995) J Neurosci Res , vol.41 , pp. 238-245
    • de la Torre, J.C.1    Fortin, T.2    Saunders, J.3
  • 4
    • 0027314240 scopus 로고
    • Can disturbed brain microcirculation cause Alzheimer's disease?
    • de la Torre JC, Mussivand T: Can disturbed brain microcirculation cause Alzheimer's disease? Neurol Res 1993;15:146-153.
    • (1993) Neurol Res , vol.15 , pp. 146-153
    • de la Torre, J.C.1    Mussivand, T.2
  • 5
    • 0034603520 scopus 로고    scopus 로고
    • Vascular risk factors for Alzheimer's disease: An epidemiologic perspective
    • Breteler MM: Vascular risk factors for Alzheimer's disease: an epidemiologic perspective. Neurobiol Aging 2000;21:153-160.
    • (2000) Neurobiol Aging , vol.21 , pp. 153-160
    • Breteler, M.M.1
  • 6
    • 33748203710 scopus 로고    scopus 로고
    • Rethinking the dementia diagnoses in a population-based study: What is Alzheimer's disease and what is vascular dementia? A study from the Kungsholmen project
    • Aguero-Torres H, Kivipelto M, von Strauss E: Rethinking the dementia diagnoses in a population-based study: what is Alzheimer's disease and what is vascular dementia? A study from the Kungsholmen project. Dement Geriatr Cogn Disord 2006;22:244-249.
    • (2006) Dement Geriatr Cogn Disord , vol.22 , pp. 244-249
    • Aguero-Torres, H.1    Kivipelto, M.2    von Strauss, E.3
  • 7
    • 33748951914 scopus 로고    scopus 로고
    • Regional cerebral blood flow reductions, heart failure and Alzheimer's disease
    • Alves TC, Busatto GF: Regional cerebral blood flow reductions, heart failure and Alzheimer's disease. Neurol Res 2006;28:579-587.
    • (2006) Neurol Res , vol.28 , pp. 579-587
    • Alves, T.C.1    Busatto, G.F.2
  • 8
    • 0042388002 scopus 로고    scopus 로고
    • Cerebral hypoperfusion induces cortical watershed microinfarcts which may further aggravate cognitive decline in Alzheimer's disease
    • Miklossy J: Cerebral hypoperfusion induces cortical watershed microinfarcts which may further aggravate cognitive decline in Alzheimer's disease. Neurol Res 2003;25:605-610.
    • (2003) Neurol Res , vol.25 , pp. 605-610
    • Miklossy, J.1
  • 9
    • 27844479696 scopus 로고    scopus 로고
    • Blood pressure, white matter lesions and medial temporal lobe atrophy: Closing the gap between vascular pathology and Alzheimer's disease?
    • Korf ES, Scheltens P, Barkhof F, de Leeuw FE: Blood pressure, white matter lesions and medial temporal lobe atrophy: closing the gap between vascular pathology and Alzheimer's disease? Dement Geriatr Cogn Disord 2005;20:331-337.
    • (2005) Dement Geriatr Cogn Disord , vol.20 , pp. 331-337
    • Korf, E.S.1    Scheltens, P.2    Barkhof, F.3    de Leeuw, F.E.4
  • 11
    • 20444383813 scopus 로고    scopus 로고
    • Cerebral hypoperfusion and clinical onset of dementia: The Rotterdam study
    • Ruitenberg A, den Heiker T, Bakker SL: Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam study. Ann Neurol 2005;57:789-794.
    • (2005) Ann Neurol , vol.57 , pp. 789-794
    • Ruitenberg, A.1    den Heiker, T.2    Bakker, S.L.3
  • 12
    • 3042730018 scopus 로고    scopus 로고
    • Alzheimer's disease is a vasocognopathy: A new term to describe its nature
    • de la Torre JC: Alzheimer's disease is a vasocognopathy: a new term to describe its nature. Neurol Res 2004;26:517-524.
    • (2004) Neurol Res , vol.26 , pp. 517-524
    • de la Torre, J.C.1
  • 13
    • 0027453765 scopus 로고
    • Untreated blood pressure level is inversely related to cognitive functioning: The Framingham Study
    • Elias MF, Wolf PA, D'Agostino RB, Cobb J, White LR: Untreated blood pressure level is inversely related to cognitive functioning: the Framingham Study. Am J Epidemiol 1993;138:353-364.
    • (1993) Am J Epidemiol , vol.138 , pp. 353-364
    • Elias, M.F.1    Wolf, P.A.2    D'Agostino, R.B.3    Cobb, J.4    White, L.R.5
  • 14
    • 2542626089 scopus 로고    scopus 로고
    • Dementia after stroke: The Framingham Study
    • Ivan CS, Seshadri S, Beiser A: Dementia after stroke: the Framingham Study. Stroke 2004;35:1264-1268.
    • (2004) Stroke , vol.35 , pp. 1264-1268
    • Ivan, C.S.1    Seshadri, S.2    Beiser, A.3
  • 15
    • 0034064133 scopus 로고    scopus 로고
    • Critically attained threshold of cerebral hypoperfusion: The CATCH hypothesis of Alzheimer's pathogenesis
    • de la Torre JC: Critically attained threshold of cerebral hypoperfusion: the CATCH hypothesis of Alzheimer's pathogenesis. Neurobiol Aging 2000;903:424-436.
    • (2000) Neurobiol Aging , vol.903 , pp. 424-436
    • de la Torre, J.C.1
  • 17
    • 28044458281 scopus 로고    scopus 로고
    • Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: Possible early events in Alzheimer's disease pathogenesis
    • Velliquette RA, O'Connor T, Vassar R: Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis. J Neurosci 2005;25:10874-10883.
    • (2005) J Neurosci , vol.25 , pp. 10874-10883
    • Velliquette, R.A.1    O'Connor, T.2    Vassar, R.3
  • 20
    • 0036218738 scopus 로고    scopus 로고
    • Alzheimer's disease as a vascular disorder: Nosological evidence
    • de la Torre JC: Alzheimer's disease as a vascular disorder: nosological evidence. Stroke 2002;33:1152-1162.
    • (2002) Stroke , vol.33 , pp. 1152-1162
    • de la Torre, J.C.1
  • 21
    • 1242331823 scopus 로고    scopus 로고
    • Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma and dialectics
    • de la Torre JC: Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma and dialectics. Lancet Neurol 2004;3:184-190.
    • (2004) Lancet Neurol , vol.3 , pp. 184-190
    • de la Torre, J.C.1
  • 24
    • 0033772113 scopus 로고    scopus 로고
    • Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
    • Wolozin B, Kellman W, Ruosseau P, Celesia G, Siegel G: Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Arch Neurol 2000;57:1439-1443.
    • (2000) Arch Neurol , vol.57 , pp. 1439-1443
    • Wolozin, B.1    Kellman, W.2    Ruosseau, P.3    Celesia, G.4    Siegel, G.5
  • 26
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • Laufs U, La Fata V, Plutzky J, Liao JK: Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation 1998;97:1129-1135.
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    La Fata, V.2    Plutzky, J.3    Liao, J.K.4
  • 27
    • 0032555154 scopus 로고    scopus 로고
    • Stroke protection by 3-hydroxy-3- methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
    • Endres M, Laufs U, Huang Z: Stroke protection by 3-hydroxy-3- methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc Natl Acad Sci USA 1998;95:8880-8885.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8880-8885
    • Endres, M.1    Laufs, U.2    Huang, Z.3
  • 28
    • 0036331059 scopus 로고    scopus 로고
    • Mechanisms of dysfunction of the nitric oxide pathway in vascular diseases
    • Maxwell AJ: Mechanisms of dysfunction of the nitric oxide pathway in vascular diseases. Nitric Oxide 2002;6:101-124.
    • (2002) Nitric Oxide , vol.6 , pp. 101-124
    • Maxwell, A.J.1
  • 29
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
    • Grundy SM, Cleeman JI, Daniels SR, Donato KA: Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005;112:2735-2752.
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3    Donato, K.A.4
  • 32
    • 0036714559 scopus 로고    scopus 로고
    • Incidence of dementia after ischemic stroke: Results of a longitudinal study
    • Desmond DW, Moroney JT, Sano M, Stern Y: Incidence of dementia after ischemic stroke: results of a longitudinal study. Stroke 2002;33:2261-2262.
    • (2002) Stroke , vol.33 , pp. 2261-2262
    • Desmond, D.W.1    Moroney, J.T.2    Sano, M.3    Stern, Y.4
  • 33
    • 0028020651 scopus 로고
    • Risk of dementia after stroke in a hospitalized cohort: Results of a longitudinal study
    • Tatemichi TK, Paik M, Bagiella E, Desmond DW, Stern Y: Risk of dementia after stroke in a hospitalized cohort: results of a longitudinal study. Neurology 1994;44:1885-1891.
    • (1994) Neurology , vol.44 , pp. 1885-1891
    • Tatemichi, T.K.1    Paik, M.2    Bagiella, E.3    Desmond, D.W.4    Stern, Y.5
  • 34
    • 0026055665 scopus 로고
    • Cerebral blood flow and metabolism studies in multi-infarct dementia
    • Brown WD, Frackowiak RSJ: Cerebral blood flow and metabolism studies in multi-infarct dementia. Alzheimer Dis Assoc Disord 1991;5:131-143.
    • (1991) Alzheimer Dis Assoc Disord , vol.5 , pp. 131-143
    • Brown, W.D.1    Frackowiak, R.S.J.2
  • 38
    • 13844298168 scopus 로고    scopus 로고
    • Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: Initial experience
    • Johnson NA, Jahng GH, Weiner MW, Miller BL, Chui HC, Jagust WJ, Gorno-Tempini ML, Schuff N: Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: initial experience. Radiology 2005;234:851-859.
    • (2005) Radiology , vol.234 , pp. 851-859
    • Johnson, N.A.1    Jahng, G.H.2    Weiner, M.W.3    Miller, B.L.4    Chui, H.C.5    Jagust, W.J.6    Gorno-Tempini, M.L.7    Schuff, N.8
  • 39
    • 0034788712 scopus 로고    scopus 로고
    • Application of positron emission tomography for evaluation of metabolism and blood flow in human brain: Normal development, aging, dementia, and stroke
    • Silverman DH, Phelps ME: Application of positron emission tomography for evaluation of metabolism and blood flow in human brain: normal development, aging, dementia, and stroke. Mol Genet Metab 2001;74:128-138.
    • (2001) Mol Genet Metab , vol.74 , pp. 128-138
    • Silverman, D.H.1    Phelps, M.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.