Distribution of amyloid deposits in the cerebral white matter of the Alzheimer's disease brain: Relationship to blood vessels

Acta Neuropathologica

Volumn 93, Issue 4, 1997, Pages 334-340

  Iwamoto, Norihiko ^a   Nishiyama, Etsuko ^a   Ohwada, Jiro ^a   Arai, Heii ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Alzheimer's disease; Amyloid deposits; Blood vessels; Cerebral white matter

Indexed keywords

AMYLOID BETA PROTEIN; FORMIC ACID;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN BLOOD VESSEL; CLINICAL ARTICLE; GRAY MATTER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; WHITE MATTER;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOIDOSIS; BRAIN; BRAIN CHEMISTRY; CEREBROVASCULAR CIRCULATION; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; STAINING AND LABELING;

EID: 0030981310     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050624     Document Type: Article

References (32)

1. Akiyama H, Yamada T, McGeer PL, Kawamata T, Tooyama I, Ishii T (1993) Columnar arrangement of β-amyloid protein deposits in the cerebral cortex of patients with Alzheimer's disease. Acta Neuropathol 85:400-403
2. Arai H, Sagi N, Noguchi I, Haga S, Ishii T, Makino Y, Kosaka K (1989) An immunohistochemical study of β-protein in Alzheimer-type dementia brains. J Neurol 236:214-217
3. Bahmanyar S, Higgins GA, Goldgabar D, Lewis DA, Morrison JH, Wilson MC, Shankar SK, Gajdusek C (1987) Localization amyloid β protein messenger RNA in brains from patients with Alzheimer's disease. Science 237:77-80
4. Behrouz N, Defossez A, Delacourte A, Mazzuca M (1990) Cortical β-amyloid. Nature 344:497
5. Behrouz N, Defossez A, Delacourte A, Mazzuca M (1991) The immunohistochemical evidence of amyloid diffuse deposits as a pathological hallmark in Alzheimer's disease. J Gerontol 46: B209-212
6. Duvernoy HM, Delmon S, Vannson JL (1981) Cortical blood vessels of the human brain. Brain Res Bull 7:519-579
7. Glenner GG, Wong CW (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120:885-890
8. Haga S, Akai K, Ishii T (1989) Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain. Acta Neuropathol 77:569-575
9. Hilbich C, Kisters-Woike B, Reed J, Masters CL, Beyreuther K (1991) Aggregation and secondary structure of synthetic amyloid βA4 peptides of Alzheimer's disease. J Mol Biol 218:149-163
10. Ikeda S, Allsop D, Glenner GG (1989) Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases. Lab Invest 60:113-122
11. Iwamoto N, Suzuki Y, Makino Y, Haga C, Kosaka K, Iizuka R (1990) Cell membrane changes in brains manifesting senile plaques: an immunohistochemical study of GM1 membranous ganglioside. Brain Res 522:152-156
12. Iwamoto N, Nishiyama E, Ohwada J, Noguchi I, Kimura M, Arai H (1995) Amyloid P component immunoreactivity in brains of Alzheimer-type dementia is reduced by formic acid pretreatment on tissue section. Neuropathology 15:64-66
13. Kang J, Lemaire H-G, Unterbech A, Salbaum JM, Masters CL, Grzeschik K-H, Multhaup G, Beyreuther K, Müller-Hill B (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell surface receptor. Nature 325:733-736
14. Kawai M, Kalaria RN, Harik SI, Perry G (1990) The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease. Am J Pathology 137:1435-1446
15. Kitamoto T, Ogomori K, Tateishi J, Prusiner SB (1987) Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids. Lab Invest 57:230-236
16. Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K (1985) Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci USA 82:4245-4249
17. Miyakawa T, Shimoji A, Kuramoto R, Higuchi Y (1982) The relationship between senile plaques and cerebral blood vessels in Alzheimer's disease and senile dementia. Virchows Arch [B] 40:121-129
18. Miyakawa T, Katsuragi S, Yamashita K, Ohuchi K (1992) Morphological study of amyloid fibrils and preamyloid deposits in the brain with Alzheimer's disease. Acta Neuropathol 83:340-346
19. Mountjoy CQ, Tomlinson BE, Gibson PH (1982) Amyloid and senile plaques and cerebral blood vessels. A semi-quantitative investigation of a possible relationship. J Neurol Sci 57:89-103
20. Pappolla MA (1989) Image analysis microspectroscopy of senile plaque capillary amyloid in Alzheimer's disease. Arch Pathol Lab Med 113:866-871
21. Pappolla MA, Omar RA, Sambamurit K, Anderson JP, Robakis NK (1992) The genesis of senile plaque. Am J Pathol 141:1151-1159
22. Scheibel AB, Duong T, Tomiyasu U (1987) Denervation microangiopathy in senile dementia, Alzheimer type. Alzheimer Dis Assoc Disord 1:19-37
23. Schultz J (1967) Cleavage at asparatic acid. In: Hirs C (ed) Methods in enzymology. Academic Press, New York, pp 255-263
24. Shoji M, Hirai S, Yamaguchi H, Harigaya Y, Kawarabayashi T (1990) Amyloid β-protein precursor accumulates in dystrophic neuntes of senile plaques in Alzheimer-type dementia. Brain Res 512:164-168
25. Siman R, Card JP, Nelson RB, Davis LG (1989) Expression of β-amyloid precursor protein in reactive astrocytes following neuronal damage. Neuron 3:275-285
26. Uchihara T, Kondo H, Akiyama H, Ikeda K (1995) White matter amyloid in Alzheimer's disease brain. Acta Neuropathol 90:51-56
27. Ulrich J (1985) Alzheimer changes in non demented patients younger than sixty-five: possible early stages of Alzheimer's disease and senile dementia of Alzheimer type. Ann Neurol 17:273-277
28. Vinters HV, Pardridge WM, Secor DL, Ishii N (1988) Immunohistochemical study of cerebral angiopathy. Am J Pathol 133:150-162
29. Wisniewski HM, Bancher C, Barcikowska M, Wen GY, Currie J (1989) Spectrum of morphological appearance of amyloid deposits in Alzheimer's disease. Acta Neuropathol 78:337-347
30. Wisniewski HM, Wegiel J, Wang KC, Lach B (1992) Ultrastructural studies of the cells forming amyloid in the cortical vessel wall in Alzheimer's disease. Acta Neuropathol 84:117-127
31. Yamaguchi H, Hirai S, Morimatsu M, Shoji M, Ihara Y (1988) A variety of cerebral amyloid deposits in the brains of the Alzheimer-type dementia demonstrated by β protein immunostaining. Acta Neuropathol 76:541-549
32. Yamaguchi H, Hirai S, Morimatsu M, Shoji M, Nakazato Y (1989) Diffuse type of senile plaques in the cerebellum of Alzheimer-type dementia demonstrated by β protein immunostain. Acta Neuropathol 77:314-319