메뉴 건너뛰기




Volumn 242, Issue 2, 1997, Pages 99-109

The emergence of mouse models of atherosclerosis and their relevance to clinical research

Author keywords

Atherosclerosis; Mice; Mutant strains; Transgenics

Indexed keywords

APOLIPOPROTEIN E; LOW DENSITY LIPOPROTEIN RECEPTOR;

EID: 0030842523     PISSN: 09546820     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2796.1997.00197.x     Document Type: Review
Times cited : (93)

References (99)
  • 1
    • 0029800187 scopus 로고    scopus 로고
    • Why you should support the American Heart Association
    • Breslow JL. Why you should support the American Heart Association. Circulation 1996; 94: 3016-22.
    • (1996) Circulation , vol.94 , pp. 3016-3022
    • Breslow, J.L.1
  • 2
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993; 362: 801-9.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 3
    • 0028945307 scopus 로고
    • Modified low density lipoprotein and its constituents augment cytokine-activated vascular cell adhesion molecule-1 gene expression in human vascular endothelial cells
    • Khan BV, Parthasarathy SS, Alexander RW, Medford RM. Modified low density lipoprotein and its constituents augment cytokine-activated vascular cell adhesion molecule-1 gene expression in human vascular endothelial cells. J Clin Invest 1995; 95: 1262-70.
    • (1995) J Clin Invest , vol.95 , pp. 1262-1270
    • Khan, B.V.1    Parthasarathy, S.S.2    Alexander, R.W.3    Medford, R.M.4
  • 4
    • 0029800916 scopus 로고    scopus 로고
    • Stability and instability: Two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995
    • Davies MJ. Stability and instability: two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995. Circulation 1996; 94: 2013-20.
    • (1996) Circulation , vol.94 , pp. 2013-2020
    • Davies, M.J.1
  • 5
    • 0021706377 scopus 로고
    • Progress in coronary artery disease risk-factor research. What remains to be done?
    • Crouse JR. Progress in coronary artery disease risk-factor research. What remains to be done? Clin Chem 1984; 30: 1125-7.
    • (1984) Clin Chem , vol.30 , pp. 1125-1127
    • Crouse, J.R.1
  • 6
    • 0020541176 scopus 로고
    • Cellular pathology of progressive atherosclerosis in the WHHL rabbit. An animal model of familial hypercholesterolemia
    • Buja LM, Kita T, Goldstein JL, Watanabe Y, Brown MS. Cellular pathology of progressive atherosclerosis in the WHHL rabbit. An animal model of familial hypercholesterolemia. Arteriosclerosis 1983; 3: 87-101.
    • (1983) Arteriosclerosis , vol.3 , pp. 87-101
    • Buja, L.M.1    Kita, T.2    Goldstein, J.L.3    Watanabe, Y.4    Brown, M.S.5
  • 7
    • 0028210943 scopus 로고
    • Insights into lipoprotein metabolism from studies in transgenic mice
    • Breslow JL. Insights into lipoprotein metabolism from studies in transgenic mice. Annu Rev Physiol 1994; 56: 797-810.
    • (1994) Annu Rev Physiol , vol.56 , pp. 797-810
    • Breslow, J.L.1
  • 8
    • 0014280713 scopus 로고
    • Experimental production of atherosclerosis in mice: II. Effects of atherogenic and high-fat diets on vascular changes in chronically and acutely irradiated mice
    • Vesselinovitch D, Wissler RW. Experimental production of atherosclerosis in mice: II. Effects of atherogenic and high-fat diets on vascular changes in chronically and acutely irradiated mice. J Atheroscler Res 1968; 8: 497-523.
    • (1968) J Atheroscler Res , vol.8 , pp. 497-523
    • Vesselinovitch, D.1    Wissler, R.W.2
  • 9
    • 0014279564 scopus 로고
    • Experimental production of atherosclerosis in mice: I. Effect of various synthetic diets and radiation on survival time, food consumption and body weight in mice
    • Vesselinovitch D, Wissler RW, Doull J. Experimental production of atherosclerosis in mice: I. Effect of various synthetic diets and radiation on survival time, food consumption and body weight in mice. J Atheroscler Res 1968; 8: 483-95.
    • (1968) J Atheroscler Res , vol.8 , pp. 483-495
    • Vesselinovitch, D.1    Wissler, R.W.2    Doull, J.3
  • 10
    • 0014535508 scopus 로고
    • Atheromata in an inbred strain of mice
    • Thompson JS. Atheromata in an inbred strain of mice. J Atheroscler Res 1969; 10: 113-22.
    • (1969) J Atheroscler Res , vol.10 , pp. 113-122
    • Thompson, J.S.1
  • 11
    • 0141470871 scopus 로고
    • Myocardial infarction in rats fed diets containing high fat. cholesterol, thiouracil, and sodium cholate
    • Thomas WA, Hartroft WS. Myocardial infarction in rats fed diets containing high fat. cholesterol, thiouracil, and sodium cholate. Circulation 1959; 19: 65.
    • (1959) Circulation , vol.19 , pp. 65
    • Thomas, W.A.1    Hartroft, W.S.2
  • 12
    • 0016913871 scopus 로고
    • Inbred mice and their hybrids as an animal model for atherosclerosis research
    • Roberts A, Thompson JS. Inbred mice and their hybrids as an animal model for atherosclerosis research. Adv Exp Med Biol 1976; 67: 313-27.
    • (1976) Adv Exp Med Biol , vol.67 , pp. 313-327
    • Roberts, A.1    Thompson, J.S.2
  • 13
    • 0021949347 scopus 로고
    • Lipoprotein levels in genetically selected mice with increased susceptibility to atherosclerosis
    • Breckenridge WC, Roberts A, Kuksis A. Lipoprotein levels in genetically selected mice with increased susceptibility to atherosclerosis. Arteriosclerosis 1985; 5: 256-64.
    • (1985) Arteriosclerosis , vol.5 , pp. 256-264
    • Breckenridge, W.C.1    Roberts, A.2    Kuksis, A.3
  • 14
    • 0021928002 scopus 로고
    • Effect of 3-methylcholanthrene on the development of aortic lesions in mice
    • Paigen B, Havens MB, Morrow A. Effect of 3-methylcholanthrene on the development of aortic lesions in mice. Cancer Res 1985; 45: 3850-55.
    • (1985) Cancer Res , vol.45 , pp. 3850-3855
    • Paigen, B.1    Havens, M.B.2    Morrow, A.3
  • 15
    • 0022003324 scopus 로고
    • Variation in susceptibility to atherosclerosis among inbred strains of mice
    • Paigen B, Morrow A, Brandon C, Mitchell D, Holmes P. Variation in susceptibility to atherosclerosis among inbred strains of mice. Atherosclerosis 1985; 57: 65-73.
    • (1985) Atherosclerosis , vol.57 , pp. 65-73
    • Paigen, B.1    Morrow, A.2    Brandon, C.3    Mitchell, D.4    Holmes, P.5
  • 17
    • 0026052863 scopus 로고
    • Pathology of atherosclerosis in cholesterol-fed, susceptible mice
    • Stewart-Phillips JL, Lough J. Pathology of atherosclerosis in cholesterol-fed, susceptible mice. Atherosclerosis 1991; 90: 211-18.
    • (1991) Atherosclerosis , vol.90 , pp. 211-218
    • Stewart-Phillips, J.L.1    Lough, J.2
  • 18
    • 0025820657 scopus 로고
    • Differential accumulation of intimal monocyte-macrophages relative to lipoproteins and lipofuscin corresponds to hemodynamic forces on cardiac valves in mice
    • Mehrabian M, Demer LL, Lusis AJ. Differential accumulation of intimal monocyte-macrophages relative to lipoproteins and lipofuscin corresponds to hemodynamic forces on cardiac valves in mice. Arterioscler Thromb 1991; 11: 947-57.
    • (1991) Arterioscler Thromb , vol.11 , pp. 947-957
    • Mehrabian, M.1    Demer, L.L.2    Lusis, A.J.3
  • 19
    • 0028105909 scopus 로고
    • Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification
    • Qiao JH, Xie PZ, Fishbein MC, Kreuzer J, Drake TA, Demer LL, Lusis AJ. Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification. Arterioscler Thromb 1994; 14: 1480-97.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1480-1497
    • Qiao, J.H.1    Xie, P.Z.2    Fishbein, M.C.3    Kreuzer, J.4    Drake, T.A.5    Demer, L.L.6    Lusis, A.J.7
  • 20
    • 0342855957 scopus 로고
    • Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice
    • Paigen B, Mitchell D, Reue K, Morrow A, Lusis AJ, LeBoeuf RC. Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. Proc Natl Acad Sci USA 1987; 84: 3763-7.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 3763-3767
    • Paigen, B.1    Mitchell, D.2    Reue, K.3    Morrow, A.4    Lusis, A.J.5    LeBoeuf, R.C.6
  • 22
    • 0023391441 scopus 로고
    • Genetic analysis of murine strains C57BL/6J and C3H/HeJ to confirm the map position of Ath-1, a gene determining atherosclerosis susceptibility
    • Paigen B, Albee D, Holmes PA, Mitchell D. Genetic analysis of murine strains C57BL/6J and C3H/HeJ to confirm the map position of Ath-1, a gene determining atherosclerosis susceptibility. Biochem Genetics 1987; 25: 501-11.
    • (1987) Biochem Genetics , vol.25 , pp. 501-511
    • Paigen, B.1    Albee, D.2    Holmes, P.A.3    Mitchell, D.4
  • 23
    • 0023551561 scopus 로고
    • Genetic analysis of strains C57BL/6J and BALB/cJ for Ath-1, a gene determining atherosclerosis susceptibility in mice
    • Paigen B, Mitchell D, Holmes PA, Albee D. Genetic analysis of strains C57BL/6J and BALB/cJ for Ath-1, a gene determining atherosclerosis susceptibility in mice. Biochem Genetics 1987; 25: 881-92.
    • (1987) Biochem Genetics , vol.25 , pp. 881-892
    • Paigen, B.1    Mitchell, D.2    Holmes, P.A.3    Albee, D.4
  • 24
    • 0025117691 scopus 로고
    • Phenotypic characterization of the Ath-1 gene controlling high density lipoprotein levels and susceptibility to atherosclerosis
    • LeBoeuf RC, Doolittle MH, Montcalm A, Martin DC, Reue K, Lusis AJ. Phenotypic characterization of the Ath-1 gene controlling high density lipoprotein levels and susceptibility to atherosclerosis. J Lipid Res 1990; 31: 91-101.
    • (1990) J Lipid Res , vol.31 , pp. 91-101
    • LeBoeuf, R.C.1    Doolittle, M.H.2    Montcalm, A.3    Martin, D.C.4    Reue, K.5    Lusis, A.J.6
  • 25
    • 0024566425 scopus 로고
    • Ath-2, a second gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice
    • Paigen B, Nesbitt MN, Mitchell D, Albee D, LeBoeuf RC. Ath-2, a second gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. Genetics 1989; 122: 163-8.
    • (1989) Genetics , vol.122 , pp. 163-168
    • Paigen, B.1    Nesbitt, M.N.2    Mitchell, D.3    Albee, D.4    LeBoeuf, R.C.5
  • 27
    • 0028618173 scopus 로고
    • Quantitative trait locus analysis of susceptibility to diet-induced atherosclerosis in recombinant inbred mice
    • Hyman RW, Frank S, Warden CH, Daluiski A, Heller R, Lusis AJ. Quantitative trait locus analysis of susceptibility to diet-induced atherosclerosis in recombinant inbred mice. Biochem Genetics 1994; 32: 397-107.
    • (1994) Biochem Genetics , vol.32 , pp. 397-1107
    • Hyman, R.W.1    Frank, S.2    Warden, C.H.3    Daluiski, A.4    Heller, R.5    Lusis, A.J.6
  • 28
    • 0027214744 scopus 로고
    • Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model
    • Warden CH, Fisler JS, Pace MJ, Svenson KL, Lusis AJ. Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model. J Clin Invest 1993; 92: 773-9.
    • (1993) J Clin Invest , vol.92 , pp. 773-779
    • Warden, C.H.1    Fisler, J.S.2    Pace, M.J.3    Svenson, K.L.4    Lusis, A.J.5
  • 29
    • 0027435969 scopus 로고
    • Involvement of the tyrosinase gene in the deposition of cardiac lipofuscin in mice. Association with aortic fatty streak development
    • Qiao JH, Welch CL, Xie PZ, Fishbein MC, Lusis AJ. Involvement of the tyrosinase gene in the deposition of cardiac lipofuscin in mice. Association with aortic fatty streak development. J Clin Invest 1993; 92: 2386-93.
    • (1993) J Clin Invest , vol.92 , pp. 2386-2393
    • Qiao, J.H.1    Welch, C.L.2    Xie, P.Z.3    Fishbein, M.C.4    Lusis, A.J.5
  • 30
    • 0027393983 scopus 로고
    • High macrophage lipoprotein lipase expression and secretion are associated in inbred murine strains with susceptibility to atherosclerosis
    • Renier G, Skamene E, DeSanctis JB, Radzioch D. High macrophage lipoprotein lipase expression and secretion are associated in inbred murine strains with susceptibility to atherosclerosis. Arterioscler Thromb 1993; 13: 190-96.
    • (1993) Arterioscler Thromb , vol.13 , pp. 190-196
    • Renier, G.1    Skamene, E.2    DeSanctis, J.B.3    Radzioch, D.4
  • 31
    • 0027233746 scopus 로고
    • Genetic control of inflammatory gene induction and NF-κ B-like transcription factor activation in response to an atherogenic diet in mice
    • Liao F, Andalibi A, deBeer FC, Fogelman AM, Lusis AJ. Genetic control of inflammatory gene induction and NF-κ B-like transcription factor activation in response to an atherogenic diet in mice. J Clin Invest 1993; 91: 2572-9.
    • (1993) J Clin Invest , vol.91 , pp. 2572-2579
    • Liao, F.1    Andalibi, A.2    DeBeer, F.C.3    Fogelman, A.M.4    Lusis, A.J.5
  • 32
    • 0028047925 scopus 로고
    • Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice
    • Liao F, Andalibi A, Qiao JH, Allayee H, Fogelman AM, Lusis AJ. Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice. J Clin Invest 1994; 94: 877-84.
    • (1994) J Clin Invest , vol.94 , pp. 877-884
    • Liao, F.1    Andalibi, A.2    Qiao, J.H.3    Allayee, H.4    Fogelman, A.M.5    Lusis, A.J.6
  • 33
    • 0028080019 scopus 로고
    • Immune-deficient mice develop typical atherosclerotic fatty streaks when fed an atherogenic diet
    • Fyfe AI, Qiao JH, Lusis AJ. Immune-deficient mice develop typical atherosclerotic fatty streaks when fed an atherogenic diet. J Clin Invest 1994; 94: 2516-20.
    • (1994) J Clin Invest , vol.94 , pp. 2516-2520
    • Fyfe, A.I.1    Qiao, J.H.2    Lusis, A.J.3
  • 34
    • 0030017111 scopus 로고    scopus 로고
    • Inhibition of atherosclerosis in CD4 T-cell-ablated and nude (nu/nu) C57BL/6 hyperlipidemic mice
    • Emeson EE, Shen ML, Bell CG, Qureshi A. Inhibition of atherosclerosis in CD4 T-cell-ablated and nude (nu/nu) C57BL/6 hyperlipidemic mice. Am J Pathol 1996; 149: 675-85.
    • (1996) Am J Pathol , vol.149 , pp. 675-685
    • Emeson, E.E.1    Shen, M.L.2    Bell, C.G.3    Qureshi, A.4
  • 35
    • 0028884797 scopus 로고
    • Chronic alcohol feeding inhibits atherogenesis in C57BL/6 hyperlipidemic mice
    • Emeson EE, Manaves V, Singer T, Tabesh M. Chronic alcohol feeding inhibits atherogenesis in C57BL/6 hyperlipidemic mice. Am J Pathol 1995; 147: 1749-58.
    • (1995) Am J Pathol , vol.147 , pp. 1749-1758
    • Emeson, E.E.1    Manaves, V.2    Singer, T.3    Tabesh, M.4
  • 36
    • 0028946497 scopus 로고
    • N-[2-[N'-pentyl-(6, 6-dimethyl - 2.4 - heptadiynyl)amino]ethyl] - (2-methyl - 1 - nap - thylthio) acetamide (FY- 087). A new acyl coenzyme a: Cholesterol acyltransferase (ACAT) inhibitor of diet-induced atherosclerosis formation in mice
    • Nagata Y, Yonemoto M, Iwasawa Y, Shimizu-Nagumo A, Hattori H, Sawazaki Y, Kamei T. N-[2-[N'-pentyl-(6, 6-dimethyl - 2.4 - heptadiynyl)amino]ethyl] - (2-methyl - 1 - nap - thylthio) acetamide (FY- 087). A new acyl coenzyme a: cholesterol acyltransferase (ACAT) inhibitor of diet-induced atherosclerosis formation in mice. Biochem Pharmacol 1995; 49: 643-51.
    • (1995) Biochem Pharmacol , vol.49 , pp. 643-651
    • Nagata, Y.1    Yonemoto, M.2    Iwasawa, Y.3    Shimizu-Nagumo, A.4    Hattori, H.5    Sawazaki, Y.6    Kamei, T.7
  • 37
    • 0029912398 scopus 로고    scopus 로고
    • Increased atherosclerosis in streptozotocin-induced diabetic mice
    • Kunjathoor VV, Wilson DL, LeBoeuf RC. Increased atherosclerosis in streptozotocin-induced diabetic mice. J Clin Invest 1996; 97: 1767-73.
    • (1996) J Clin Invest , vol.97 , pp. 1767-1773
    • Kunjathoor, V.V.1    Wilson, D.L.2    LeBoeuf, R.C.3
  • 38
    • 0028958053 scopus 로고
    • The effect of population density on the development of experimental atherosclerosis in female mice
    • Lin AH, Castle CK, Melchior GW, Marotti KR. The effect of population density on the development of experimental atherosclerosis in female mice. Atherosclerosis 1995; 115: 85-8.
    • (1995) Atherosclerosis , vol.115 , pp. 85-88
    • Lin, A.H.1    Castle, C.K.2    Melchior, G.W.3    Marotti, K.R.4
  • 39
    • 0026725757 scopus 로고
    • Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
    • Plump AS, Smith JD, Hayek T, Aalto-Setala K, Walsh A, Verstuyft JG, et al. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 1992; 71: 343-53.
    • (1992) Cell , vol.71 , pp. 343-353
    • Plump, A.S.1    Smith, J.D.2    Hayek, T.3    Aalto-Setala, K.4    Walsh, A.5    Verstuyft, J.G.6
  • 40
    • 0026592806 scopus 로고
    • Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
    • Zhang SH, Reddick RL, Piedrahita JA, Maeda N. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 1992; 258: 468-71.
    • (1992) Science , vol.258 , pp. 468-471
    • Zhang, S.H.1    Reddick, R.L.2    Piedrahita, J.A.3    Maeda, N.4
  • 41
    • 0027958084 scopus 로고
    • ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree
    • Nakashima Y, Plump AS, Raines EW, Breslow JL, Ross R. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb 1994; 14: 133-40.
    • (1994) Arterioscler Thromb , vol.14 , pp. 133-140
    • Nakashima, Y.1    Plump, A.S.2    Raines, E.W.3    Breslow, J.L.4    Ross, R.5
  • 42
    • 0029134887 scopus 로고
    • Apolipoprotein E and the apolipoprotein E-deficient mouse
    • Plump AS, Breslow JL. Apolipoprotein E and the apolipoprotein E-deficient mouse. Annu Rev Nutr 1995; 15: 495-518.
    • (1995) Annu Rev Nutr , vol.15 , pp. 495-518
    • Plump, A.S.1    Breslow, J.L.2
  • 43
    • 0027976942 scopus 로고
    • Atherosclerosis in mice lacking apoE. Evaluation of lesional development and progression
    • Reddick RL, Zhang SH, Maeda N. Atherosclerosis in mice lacking apoE. Evaluation of lesional development and progression. Arterioscler Thromb 1994; 14: 141-7.
    • (1994) Arterioscler Thromb , vol.14 , pp. 141-147
    • Reddick, R.L.1    Zhang, S.H.2    Maeda, N.3
  • 44
    • 0029818059 scopus 로고    scopus 로고
    • Lymphocyte populations in atherosclerotic lesions of apoE -/-and LDL receptor -/- Mice. Decreasing density with disease progression
    • Roselaar SE, Kakkanathu PX, Daugherty A. Lymphocyte populations in atherosclerotic lesions of apoE -/-and LDL receptor -/- mice. Decreasing density with disease progression. Arterioscler Thromb Vasc Biol 1996; 16: 1013-18.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1013-1018
    • Roselaar, S.E.1    Kakkanathu, P.X.2    Daugherty, A.3
  • 45
    • 0029079926 scopus 로고
    • Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E
    • Smith JD, Trogan E, Ginsberg M, Grigaux C, Tian J, Miyata M. Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E. Proc Natl Acad Sci USA 1995; 92: 8264-8.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8264-8268
    • Smith, J.D.1    Trogan, E.2    Ginsberg, M.3    Grigaux, C.4    Tian, J.5    Miyata, M.6
  • 46
    • 0030017028 scopus 로고    scopus 로고
    • Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apolipoprotein-E-deficient mice
    • Zhou X, Stemme S, Hansson GK. Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apolipoprotein-E-deficient mice. Am J Pathol 1996; 149: 359-66.
    • (1996) Am J Pathol , vol.149 , pp. 359-366
    • Zhou, X.1    Stemme, S.2    Hansson, G.K.3
  • 47
    • 0028198105 scopus 로고
    • ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum
    • Palinski W, Ord VA, Plump AS, Breslow JL, Steinberg D, Witztum JL. ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum. Arterioscler Thromb 1994; 14: 605-16.
    • (1994) Arterioscler Thromb , vol.14 , pp. 605-616
    • Palinski, W.1    Ord, V.A.2    Plump, A.S.3    Breslow, J.L.4    Steinberg, D.5    Witztum, J.L.6
  • 48
    • 0028862192 scopus 로고
    • Quantitation of atherosclerosis in murine models: Correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice
    • Tangirala RK, Rubin EM, Palinski W. Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice. J Lipid Res 1995; 16: 2320-28.
    • (1995) J Lipid Res , vol.16 , pp. 2320-2328
    • Tangirala, R.K.1    Rubin, E.M.2    Palinski, W.3
  • 49
    • 0016817465 scopus 로고
    • Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan. Hawaii and California: Introduction
    • Syme SL, Marmot MG, Kagan A, Kato H, Rhoads G. Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan. Hawaii and California: introduction. Am J Epidemiol 1975; 102: 477-80.
    • (1975) Am J Epidemiol , vol.102 , pp. 477-480
    • Syme, S.L.1    Marmot, M.G.2    Kagan, A.3    Kato, H.4    Rhoads, G.5
  • 50
    • 0026013009 scopus 로고
    • Effects of recombinant human macrophage colony-stimulating factor on plasma cholesterol levels
    • Stoudemire JB, Garnick MB. Effects of recombinant human macrophage colony-stimulating factor on plasma cholesterol levels. Blood 1991; 77: 750-55.
    • (1991) Blood , vol.77 , pp. 750-755
    • Stoudemire, J.B.1    Garnick, M.B.2
  • 51
    • 0024327718 scopus 로고
    • Serum cholesterol-lowering activity of human monocytic colony-stimulating factor
    • Motoyoshi K, Takaku E. Serum cholesterol-lowering activity of human monocytic colony-stimulating factor. Lancet 1989; 2: 326-7.
    • (1989) Lancet , vol.2 , pp. 326-327
    • Motoyoshi, K.1    Takaku, E.2
  • 52
    • 0028177462 scopus 로고
    • Recombinant human macrophage colony-stimulating factor reduces plasma cholesterol and carrageenan granuloma foam cell formation in Watanabe heritable hyperlipidemic rabbits
    • Schaub RG, Bree MP, Hayes LL, Rudd MA, Rabbani L, Loscalzo J, Clinton SK. Recombinant human macrophage colony-stimulating factor reduces plasma cholesterol and carrageenan granuloma foam cell formation in Watanabe heritable hyperlipidemic rabbits. Arterioscler Thromb 1994; 14: 70-76.
    • (1994) Arterioscler Thromb , vol.14 , pp. 70-76
    • Schaub, R.G.1    Bree, M.P.2    Hayes, L.L.3    Rudd, M.A.4    Rabbani, L.5    Loscalzo, J.6    Clinton, S.K.7
  • 53
    • 0031001972 scopus 로고    scopus 로고
    • T and B lymphocytes play a minor role in atheroscleritic plaque formation in the apolipoprotein E-deficient mouse
    • Dansky HM, Charlton SA, McGee Harper M, Smith JD. T and B lymphocytes play a minor role in atheroscleritic plaque formation in the apolipoprotein E-deficient mouse. Proc Natl Acad Sci USA 1997; 94: 4642-6.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4642-4646
    • Dansky, H.M.1    Charlton, S.A.2    McGee Harper, M.3    Smith, J.D.4
  • 54
    • 0028167663 scopus 로고
    • Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice
    • Paszty C, Maeda N, Verstuyft J, Rubin KM. Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. J Clin Invest 1994; 94: 899-903.
    • (1994) J Clin Invest , vol.94 , pp. 899-903
    • Paszty, C.1    Maeda, N.2    Verstuyft, J.3    Rubin, K.M.4
  • 55
    • 0028025262 scopus 로고
    • Human apolipoprotein A-1 gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse
    • Plump AS, Scott CJ, Breslow JL. Human apolipoprotein A-1 gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse. Proc Natl Acad Sci U S A 1994; 91: 9607-11.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 9607-9611
    • Plump, A.S.1    Scott, C.J.2    Breslow, J.L.3
  • 60
    • 0029091281 scopus 로고
    • Apolipoprotein E deficiency in mice: Gene replacement and prevention of atherosclerosis using adenovirus vectors
    • Kashyap VS, Santamarina-Fojo S, Brown DR, Parrott CL. Applebaum-Bowden D, Meyn S et al. Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors. J Clin Invest 1995; 96: 1612-20.
    • (1995) J Clin Invest , vol.96 , pp. 1612-1620
    • Kashyap, V.S.1    Santamarina-Fojo, S.2    Brown, D.R.3    Parrott, C.L.4    Applebaum-Bowden, D.5    Meyn, S.6
  • 61
    • 0029618108 scopus 로고
    • Cytochrome P450 1A. 1. promoter as a genetic switch for the regulatable and physiological expression of a plasma protein in transgenic mice
    • Smith JD, Wong E, Ginsberg M. Cytochrome P450 1A. 1. promoter as a genetic switch for the regulatable and physiological expression of a plasma protein in transgenic mice. Proc Natl Acad Sci USA 1930; 1995: 92: 11926-30.
    • (1930) Proc Natl Acad Sci USA , vol.92 , pp. 11926-11930
    • Smith, J.D.1    Wong, E.2    Ginsberg, M.3
  • 62
    • 0024529337 scopus 로고
    • Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis
    • Kraft HG, Menzel HJ, Hoppichler F, Vogel W, Utermann G. Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis. J Clin Invest 1989; 83: 137-42.
    • (1989) J Clin Invest , vol.83 , pp. 137-142
    • Kraft, H.G.1    Menzel, H.J.2    Hoppichler, F.3    Vogel, W.4    Utermann, G.5
  • 63
    • 0025878638 scopus 로고
    • Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation
    • Linton MF, Gish R, Hubl ST, Butler E, Esquivel C, Bry WI, et al. Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation. J Clin Invest 1991; 88: 270-81.
    • (1991) J Clin Invest , vol.88 , pp. 270-281
    • Linton, M.F.1    Gish, R.2    Hubl, S.T.3    Butler, E.4    Esquivel, C.5    Bry, W.I.6
  • 64
    • 0024299370 scopus 로고
    • Apolipoprotein E. cholesterol transport protein with expanding role in cell biology
    • Mahley RW. Apolipoprotein E. cholesterol transport protein with expanding role in cell biology. Science 1988; 240: 622-30.
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 65
    • 0028944150 scopus 로고
    • Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation
    • Linton MF, Atkinson JB, Fazio S. Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation. Science 1995; 267: 1034-7.
    • (1995) Science , vol.267 , pp. 1034-1037
    • Linton, M.F.1    Atkinson, J.B.2    Fazio, S.3
  • 66
    • 0029081525 scopus 로고
    • Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation
    • Boisvert WA, Spangenberg J, Curtiss LK. Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation. J Clin Invest 1995; 96: 1118-24.
    • (1995) J Clin Invest , vol.96 , pp. 1118-1124
    • Boisvert, W.A.1    Spangenberg, J.2    Curtiss, L.K.3
  • 68
    • 0023769963 scopus 로고
    • Atherosclerosis and apoprotein E. An enigmatic relationship
    • Getz GS, Mazzone T, Soltys P, Bates SR. Atherosclerosis and apoprotein E. An enigmatic relationship. Arch Pathol Lab Med 1988; 112: 1048-55.
    • (1988) Arch Pathol Lab Med , vol.112 , pp. 1048-1055
    • Getz, G.S.1    Mazzone, T.2    Soltys, P.3    Bates, S.R.4
  • 69
    • 0029804198 scopus 로고    scopus 로고
    • Cyclic AMP induces apolipoprotein E binding activity and promotes cholesterol efflux from a macrophage cell line to apolipoprotein acceptors
    • Smith JD, Miyata M, Ginsberg M, Grigaux C, Shmookler E, Plump AS. Cyclic AMP induces apolipoprotein E binding activity and promotes cholesterol efflux from a macrophage cell line to apolipoprotein acceptors. J Biol Chem 1996; 271: 30647-55.
    • (1996) J Biol Chem , vol.271 , pp. 30647-30655
    • Smith, J.D.1    Miyata, M.2    Ginsberg, M.3    Grigaux, C.4    Shmookler, E.5    Plump, A.S.6
  • 70
    • 0030480126 scopus 로고    scopus 로고
    • Apolipoprotein-mediated removal of cellular cholesterol and phospholipids
    • Oram JF, Yokoyama S. Apolipoprotein-mediated removal of cellular cholesterol and phospholipids. J Lipid Res 1996; 37: 2473-91.
    • (1996) J Lipid Res , vol.37 , pp. 2473-2491
    • Oram, J.F.1    Yokoyama, S.2
  • 71
    • 0028883354 scopus 로고
    • Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice
    • Bellosta S, Mahley RW, Sanan DA, Murata J, Newland DL, Taylor JM, Pitas RE. Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice. J Clin Invest 1995; 96: 2170-79.
    • (1995) J Clin Invest , vol.96 , pp. 2170-2179
    • Bellosta, S.1    Mahley, R.W.2    Sanan, D.A.3    Murata, J.4    Newland, D.L.5    Taylor, J.M.6    Pitas, R.E.7
  • 72
    • 0030011282 scopus 로고    scopus 로고
    • Accelerated atheromatous lesions in mouse hearts transplanted to apolipoprotein-E-deficient recipients
    • Russell PS, Chase CM, Colvin RB. Accelerated atheromatous lesions in mouse hearts transplanted to apolipoprotein-E-deficient recipients. Am J Pathol 1996; 149: 91-9.
    • (1996) Am J Pathol , vol.149 , pp. 91-99
    • Russell, P.S.1    Chase, C.M.2    Colvin, R.B.3
  • 73
    • 0027258140 scopus 로고
    • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
    • Ishibashi S, Brown MS, Goldstein JL, Gerard RD, Hammer RE, Herz J. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J Clin Invest 1993; 92: 883-93.
    • (1993) J Clin Invest , vol.92 , pp. 883-893
    • Ishibashi, S.1    Brown, M.S.2    Goldstein, J.L.3    Gerard, R.D.4    Hammer, R.E.5    Herz, J.6
  • 74
    • 0028345073 scopus 로고
    • Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice
    • Ishibashi S, Goldstein JL, Brown MS, Herz J, Burns DK. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. J Clin Invest 1994; 93: 1885-93.
    • (1994) J Clin Invest , vol.93 , pp. 1885-1893
    • Ishibashi, S.1    Goldstein, J.L.2    Brown, M.S.3    Herz, J.4    Burns, D.K.5
  • 76
    • 0027251885 scopus 로고
    • Low density lipoprotein receptor internalizes low density and very low density lipoproteins that are bound to heparan sulfate proteoglycans via lipoprotein lipase
    • Mulder M, Lombardi P, Jansen H, van Berkel TJ, Frants RR, Havekes LM. Low density lipoprotein receptor internalizes low density and very low density lipoproteins that are bound to heparan sulfate proteoglycans via lipoprotein lipase. J Biol Chem 1993; 268: 9369-75.
    • (1993) J Biol Chem , vol.268 , pp. 9369-9375
    • Mulder, M.1    Lombardi, P.2    Jansen, H.3    Van Berkel, T.J.4    Frants, R.R.5    Havekes, L.M.6
  • 77
    • 0030002205 scopus 로고    scopus 로고
    • Suppression of diet-induced atherosclerosis in low density lipoprotein receptor knockout mice overexpressing lipoprotein lipase
    • Shimada M, Ishibashi S, Inaba T, Yagyu H, Harada K, Osuga JI et al. Suppression of diet-induced atherosclerosis in low density lipoprotein receptor knockout mice overexpressing lipoprotein lipase. Pror Natl Acad Sci U S A 1996; 93: 7242-6.
    • (1996) Pror Natl Acad Sci U S A , vol.93 , pp. 7242-7246
    • Shimada, M.1    Ishibashi, S.2    Inaba, T.3    Yagyu, H.4    Harada, K.5    Osuga, J.I.6
  • 78
    • 0028240649 scopus 로고
    • Atherosclerosis in mice: Getting to the heart of a polygenic disorder
    • Rubin EM, Smith DJ. Atherosclerosis in mice: getting to the heart of a polygenic disorder. Trends Genet 1994; 10: 199-203.
    • (1994) Trends Genet , vol.10 , pp. 199-203
    • Rubin, E.M.1    Smith, D.J.2
  • 79
    • 0025902231 scopus 로고
    • Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI
    • Rubin EM, Krauss RM, Spangler EA, Verstuyft JG, Clift SM. Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI. Nature 1991; 353: 265-7.
    • (1991) Nature , vol.353 , pp. 265-267
    • Rubin, E.M.1    Krauss, R.M.2    Spangler, E.A.3    Verstuyft, J.G.4    Clift, S.M.5
  • 81
    • 0028280609 scopus 로고
    • The properties of HDL in genetically engineered mice
    • Schultz JR, Rubin EM. The properties of HDL in genetically engineered mice. Curr Opin Lipidol 1994; 5: 126-37.
    • (1994) Curr Opin Lipidol , vol.5 , pp. 126-137
    • Schultz, J.R.1    Rubin, E.M.2
  • 82
    • 0027373567 scopus 로고
    • Protein composition determines the anti-atherogenic properties of HDL in transgenic mice
    • Schultz JR, Verstuyft JG, Gong EL, Nichols AV, Rubin EM. Protein composition determines the anti-atherogenic properties of HDL in transgenic mice. Nature 1993; 365: 762-4.
    • (1993) Nature , vol.365 , pp. 762-764
    • Schultz, J.R.1    Verstuyft, J.G.2    Gong, E.L.3    Nichols, A.V.4    Rubin, E.M.5
  • 84
    • 0028832488 scopus 로고
    • Relative contributions of apolipoprotein(a) and apolipoprotein-B to the development of fatty lesions in the proximal aorta of mice
    • Mancini FP, Newland DL, Mooser V, Murata J, Marcovina S, Young SG et al. Relative contributions of apolipoprotein(a) and apolipoprotein-B to the development of fatty lesions in the proximal aorta of mice. Arterioscler Thromb Vasc Biol 1995; 15: 1911-16.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1911-1916
    • Mancini, F.P.1    Newland, D.L.2    Mooser, V.3    Murata, J.4    Marcovina, S.5    Young, S.G.6
  • 86
    • 0028596350 scopus 로고
    • Human apolipoprotein A-I prevents atherosclerosis associated with apolipoprotein(a) in transgenic mice
    • Liu AC, Lawn RM, Verstuyft JG, Rubin EM. Human apolipoprotein A-I prevents atherosclerosis associated with apolipoprotein(a) in transgenic mice. J Lipid Res 1994; 35: 2263-7.
    • (1994) J Lipid Res , vol.35 , pp. 2263-2267
    • Liu, A.C.1    Lawn, R.M.2    Verstuyft, J.G.3    Rubin, E.M.4
  • 87
    • 0028960478 scopus 로고
    • Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet
    • Purcell-Huynh DA, Farese RV Jr, Johnson DF, Flynn LM, Pierotti V, Newland DL et al. Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet. J Clin Invest 1995; 95: 2246-57.
    • (1995) J Clin Invest , vol.95 , pp. 2246-2257
    • Purcell-Huynh, D.A.1    Farese Jr., R.V.2    Johnson, D.F.3    Flynn, L.M.4    Pierotti, V.5    Newland, D.L.6
  • 88
    • 0028125108 scopus 로고
    • Effect of human apoE4 on the clearance of chylomicron-like lipid emulsions and atherogenesis in transgenic mice
    • Mortimer BC, Redgrave TG, Spangler EA, Verstuyft JG, Rubin EM. Effect of human apoE4 on the clearance of chylomicron-like lipid emulsions and atherogenesis in transgenic mice. Arterioscler Thromb 1994; 14: 1542-52.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1542-1552
    • Mortimer, B.C.1    Redgrave, T.G.2    Spangler, E.A.3    Verstuyft, J.G.4    Rubin, E.M.5
  • 89
    • 0028890170 scopus 로고
    • Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall
    • Shimano H, Ohsuga J, Shimada M, Namba Y, Gotoda T, Harada K et al. Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall. J Clin Invest 1995; 95: 469-76.
    • (1995) J Clin Invest , vol.95 , pp. 469-476
    • Shimano, H.1    Ohsuga, J.2    Shimada, M.3    Namba, Y.4    Gotoda, T.5    Harada, K.6
  • 90
    • 0028105142 scopus 로고
    • Susceptibility to diet-induced atherosclerosis in transgenic mice expressing a dysfunctional human apolipoprotein E (Arg 112. Cys142)
    • Fazio S, Sanan DA, Lee YL, Ji ZS, Mahley RW, Rall SC Jr. Susceptibility to diet-induced atherosclerosis in transgenic mice expressing a dysfunctional human apolipoprotein E (Arg 112. Cys142). Arterioscler Thromb 1994; 14: 1873-9.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1873-1879
    • Fazio, S.1    Sanan, D.A.2    Lee, Y.L.3    Ji, Z.S.4    Mahley, R.W.5    Rall Jr., S.C.6
  • 92
    • 0026531139 scopus 로고
    • Overexpression of apolipoprotein E in transgenic mice: Marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia
    • Shimano H, Yamada N, Katsuki M, Shimada M, Gotoda T, Harada K et al. Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia. Proc Natl Acad Sci U S A 1992; 89: 1750-54.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 1750-1754
    • Shimano, H.1    Yamada, N.2    Katsuki, M.3    Shimada, M.4    Gotoda, T.5    Harada, K.6
  • 93
    • 0027325516 scopus 로고
    • Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein
    • Marotti KR, Castle CK, Boyle TP, Lin AH, Murray RW, Melchior GW. Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein. Nature 1993; 364: 73-5.
    • (1993) Nature , vol.364 , pp. 73-75
    • Marotti, K.R.1    Castle, C.K.2    Boyle, T.P.3    Lin, A.H.4    Murray, R.W.5    Melchior, G.W.6
  • 94
    • 0028784246 scopus 로고
    • Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene
    • Hayek T, Masucci-Magoulas L, Jiang X, Walsh A, Rubin E, Breslow JL, Tall AR. Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene. J Clin Invest 1995; 96: 2071-4.
    • (1995) J Clin Invest , vol.96 , pp. 2071-2074
    • Hayek, T.1    Masucci-Magoulas, L.2    Jiang, X.3    Walsh, A.4    Rubin, E.5    Breslow, J.L.6    Tall, A.R.7
  • 95
    • 0028305225 scopus 로고
    • Human hepatic triglyceride lipase expression reduces high density lipoprotein and aortic cholesterol in cholesterol-fed transgenic mice
    • Busch SJ, Barnhart RL, Martin GA, Fitzgerald MC, Yates MT, Mao SJ et al. Human hepatic triglyceride lipase expression reduces high density lipoprotein and aortic cholesterol in cholesterol-fed transgenic mice. J Biol Chem 1994; 269: 16376-82.
    • (1994) J Biol Chem , vol.269 , pp. 16376-16382
    • Busch, S.J.1    Barnhart, R.L.2    Martin, G.A.3    Fitzgerald, M.C.4    Yates, M.T.5    Mao, S.J.6
  • 96
    • 0027330901 scopus 로고
    • Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice
    • Li H, Reddick RL, Maeda N. Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice. Arterioscler Thromb 1993; 13: 1814-21.
    • (1993) Arterioscler Thromb , vol.13 , pp. 1814-1821
    • Li, H.1    Reddick, R.L.2    Maeda, N.3
  • 97
    • 0028146233 scopus 로고
    • Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption
    • Zhang SH, Reddick RL, Burkey B, Maeda N. Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption. J Clin Invest 1994; 94: 937-45.
    • (1994) J Clin Invest , vol.94 , pp. 937-945
    • Zhang, S.H.1    Reddick, R.L.2    Burkey, B.3    Maeda, N.4
  • 99
    • 0029955427 scopus 로고    scopus 로고
    • Accelerated atherosclerosis in mice lacking tumor necrosis factor receptor p55
    • Schreyer SA, Peschon JJ, LeBoeuf RC. Accelerated atherosclerosis in mice lacking tumor necrosis factor receptor p55 J Biol Chem 1996; 271: 26174-8.
    • (1996) J Biol Chem , vol.271 , pp. 26174-26178
    • Schreyer, S.A.1    Peschon, J.J.2    LeBoeuf, R.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.