The DNA-damage response: New molecular insights and new approaches to cancer therapy

Biochemical Society Transactions

Volumn 37, Issue 3, 2009, Pages 483-494

  Jackson, Stephen P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Cancer; Cancer therapy; Cell cycle; DNA damage; DNA repair

Indexed keywords

ATM PROTEIN; ATR PROTEIN; AZD 2281; BRCA1 PROTEIN; BRCA2 PROTEIN; DNA DEPENDENT PROTEIN KINASE; KU 0059436; KU ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

BREAST CANCER; CANCER THERAPY; CELL CYCLE REGULATION; CLINICAL TRIAL; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DRUG INDUSTRY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; DNA DAMAGE; DNA REPAIR; HUMANS; MODELS, BIOLOGICAL; NEOPLASMS; PHTHALAZINES; PIPERAZINES; POLY(ADP-RIBOSE) POLYMERASES; SIGNAL TRANSDUCTION;

EID: 67749104769     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0370483     Document Type: Review

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