Phosphoinositide 3-kinases and their role in inflammation: Potential clinical targets in atherosclerosis?

Clinical Science

Volumn 116, Issue 11-12, 2009, Pages 791-804

  Fougerat, Anne ^a   Gayral, Stéphanie ^a   Malet, Nicole ^a   Briand Mesange, Fabienne ^a   Breton Douillon, Monique ^a   Laffargue, Muriel ^a  

^a INSERM   (France)

Author keywords

Atherogenesis; Immune cells; Inflammation; Phosphoinositide 3 kinase; Plaque rupture; Thrombosis

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 5 (6 QUINOXALINYLMETHYLENE) 2,4 THIAZOLIDINEDIONE; 5 [5 (4 FLUORO 2 HYDROXYPHENYL)FURFURYLIDENE] 2,4 THIAZOLIDINEDIONE; AS 604850; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; UNCLASSIFIED DRUG; WORTMANNIN;

ADAPTIVE IMMUNITY; ANTIINFLAMMATORY ACTIVITY; ATHEROGENESIS; ATHEROSCLEROSIS; CELL FUNCTION; CHOLESTEROL TRANSPORT; CYTOKINE RELEASE; DRUG TARGETING; ENZYME INHIBITION; EOSINOPHIL; HEART INFARCTION; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; INFLAMMATION; INFLAMMATORY CELL; INNATE IMMUNITY; LYMPHOCYTE FUNCTION; MAST CELL; MICROBIAL ACTIVITY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; REVIEW; STROKE; T LYMPHOCYTE; THROMBOCYTE FUNCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ATHEROSCLEROSIS; BLOOD PLATELETS; CYTOKINES; HUMANS; INFLAMMATION; LEUKOCYTES; MACROPHAGES; NEUTROPHILS; T-LYMPHOCYTES;

EID: 67649243798     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20080549     Document Type: Review

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